antimycin has been researched along with balsalazide* in 1 studies
1 other study(ies) available for antimycin and balsalazide
| Article | Year |
|---|---|
Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
We report here an extensive structure-activity relationship study of balsalazide, which was previously identified in a high-throughput screening as an inhibitor of Sirt5. To get a closer understanding why this compound is able to inhibit Sirt5, we initially performed docking experiments comparing the binding mode of a succinylated peptide as the natural substrate and balsalazide with Sirt5 in the presence of NAD Topics: Drug Design; Histone Deacetylase Inhibitors; Mesalamine; Molecular Docking Simulation; Phenylhydrazines; Protein Conformation; Salicylic Acid; Sirtuins; Structure-Activity Relationship | 2020 |