anticodon has been researched along with spiroiminodihydantoin* in 1 studies
1 other study(ies) available for anticodon and spiroiminodihydantoin
Article | Year |
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Guanosine in a single stranded region of anticodon stem-loop tRNA models is prone to oxidatively generated damage resulting in dehydroguanidinohydantoin and spiroiminodihydantoin lesions.
Oxidation of RNA hairpin models corresponding to anticodon stem-loop (ASL) of transfer RNA led to RNA damage consisting solely of a unique loop guanine oxidation. Manganese porphyrin/oxone treatment of RNA resulted in dehydroguanidinohydantoin (DGh; major) and/or spiroiminodihydantoin (Sp) lesions. Ribose damage was not observed. This two-electron transfer oxidation reaction allowed the identification of guanine oxidation products for further study of RNA species carrying a unique lesion at a single G to investigate their biological impact. Topics: Anticodon; Guanidines; Guanosine; Hydantoins; Models, Chemical; Oxidation-Reduction; Ribose; RNA, Transfer; Spiro Compounds | 2015 |