Page last updated: 2024-09-03

antibiotic g 418 and ptc 124

antibiotic g 418 has been researched along with ptc 124 in 8 studies

Compound Research Comparison

Studies
(antibiotic g 418)
Trials
(antibiotic g 418)
Recent Studies (post-2010)
(antibiotic g 418)
Studies
(ptc 124)
Trials
(ptc 124)
Recent Studies (post-2010) (ptc 124)
515010219117157

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (87.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Baldassano, S; Di Leonardo, A; Lentini, L; Melfi, R; Pace, A; Pibiri, I; Ricco Galluzzo, P; Tutone, M1
Braverman, NE; Di Pietro, E; Dranchak, PK; Hacia, JG; Oesch, N; Snowden, A; Steinberg, SJ1
Christodoulou, J; Ho, G; Reichardt, J1
Gartner, U; McElroy, SP; McLean, WH; Nomura, T; Torrie, LS; Warbrick, E; Wood, G1
DiGiovanna, JJ; Gatti, RA; Khan, SG; Kraemer, KH; Kuschal, C1
Beekman, JM; de Winter-de Groot, KM; Dekkers, JF; Janssens, HM; Kruisselbrink, E; van der Ent, CK; Vijftigschild, LA; Vonk, AM; Zomer-van Ommen, DD1
Carr, AF; Cheetham, ME; Chen, LL; Coffey, PJ; da Cruz, L; J K Smart, M; Moore, AT; Muthiah, MN; Nommiste, B; Powner, MB; R Lane, A; Ramsden, CM; Webster, AR1
Gao, H; Liu, X; Qiu, C; Zhang, B; Zhang, Y1

Other Studies

8 other study(ies) available for antibiotic g 418 and ptc 124

ArticleYear
Rescuing the CFTR protein function: Introducing 1,3,4-oxadiazoles as translational readthrough inducing drugs.
    European journal of medicinal chemistry, 2018, Nov-05, Volume: 159

    Topics: Cell Survival; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Oxadiazoles; RNA, Messenger; Structure-Activity Relationship

2018
Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:5

    Topics: Alleles; Animals; CHO Cells; Chondrodysplasia Punctata, Rhizomelic; Codon, Nonsense; Cricetinae; Cricetulus; Female; Fibroblasts; Gentamicins; Humans; Lipid Metabolism; Membrane Proteins; Oxadiazoles; Peroxisomal Biogenesis Factor 2; Peroxisomal Disorders; Peroxisomal Targeting Signal 2 Receptor; Plasmalogens; Receptors, Cytoplasmic and Nuclear

2011
In vitro read-through of phenylalanine hydroxylase (PAH) nonsense mutations using aminoglycosides: a potential therapy for phenylketonuria.
    Journal of inherited metabolic disease, 2013, Volume: 36, Issue:6

    Topics: Aminoglycosides; Animals; Chlorocebus aethiops; Codon, Nonsense; COS Cells; Drug Evaluation, Preclinical; Genetic Therapy; Gentamicins; HEK293 Cells; Humans; Oxadiazoles; Phenylalanine Hydroxylase; Phenylketonurias

2013
A lack of premature termination codon read-through efficacy of PTC124 (Ataluren) in a diverse array of reporter assays.
    PLoS biology, 2013, Volume: 11, Issue:6

    Topics: Animals; beta-Galactosidase; Biological Assay; Cell Line; Codon, Nonsense; Collagen Type VII; Genes, Reporter; Gentamicins; Humans; Luciferases, Firefly; Oxadiazoles; Transfection

2013
Repair of UV photolesions in xeroderma pigmentosum group C cells induced by translational readthrough of premature termination codons.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Nov-26, Volume: 110, Issue:48

    Topics: Codon, Nonsense; DNA Primers; DNA Repair; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorescent Antibody Technique; Gentamicins; Humans; Immunoblotting; Luciferases; Oxadiazoles; Real-Time Polymerase Chain Reaction; RNA Stability; Skin Neoplasms; Xeroderma Pigmentosum

2013
Limited premature termination codon suppression by read-through agents in cystic fibrosis intestinal organoids.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016, Volume: 15, Issue:2

    Topics: Cells, Cultured; Coccidiostats; Codon, Nonsense; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Gentamicins; Humans; Organoids; Oxadiazoles; RNA

2016
Rescue of the MERTK phagocytic defect in a human iPSC disease model using translational read-through inducing drugs.
    Scientific reports, 2017, 03-03, Volume: 7, Issue:1

    Topics: Adult; c-Mer Tyrosine Kinase; Gentamicins; Humans; Induced Pluripotent Stem Cells; Male; Oxadiazoles; Peptide Chain Elongation, Translational; Phagocytosis; Photoreceptor Cells; Retinal Pigment Epithelium; Retinitis Pigmentosa

2017
Nonsense suppression induced readthrough of a novel PAX6 mutation in patient-derived cells of congenital aniridia.
    Molecular genetics & genomic medicine, 2020, Volume: 8, Issue:5

    Topics: Adult; Aniridia; Cells, Cultured; Child; Female; Gentamicins; Haploinsufficiency; Heterozygote; Humans; INDEL Mutation; Male; Middle Aged; Nonsense Mediated mRNA Decay; Oxadiazoles; PAX6 Transcription Factor; Pedigree

2020