Compounds > antibiotic g 418
Page last updated: 2024-09-03

antibiotic g 418 and paromomycin

antibiotic g 418 has been researched along with paromomycin in 14 studies

Compound Research Comparison

Studies
(antibiotic g 418)		Trials
(antibiotic g 418)		Recent Studies (post-2010)
(antibiotic g 418)		Studies
(paromomycin)		Trials
(paromomycin)		Recent Studies (post-2010) (paromomycin)
51501021,42290292

Protein Interaction Comparison

ProteinTaxonomyantibiotic g 418 (IC50)paromomycin (IC50)
30S ribosomal protein S6Escherichia coli K-120.0355
30S ribosomal protein S7Escherichia coli K-120.0355
50S ribosomal protein L15Escherichia coli K-120.0355
50S ribosomal protein L10Escherichia coli K-120.0355
50S ribosomal protein L11Escherichia coli K-120.0355
50S ribosomal protein L7/L12Escherichia coli K-120.0355
50S ribosomal protein L19Escherichia coli K-120.0355
50S ribosomal protein L1Escherichia coli K-120.0355
50S ribosomal protein L20Escherichia coli K-120.0355
50S ribosomal protein L27Escherichia coli K-120.0355
50S ribosomal protein L28Escherichia coli K-120.0355
50S ribosomal protein L29Escherichia coli K-120.0355
50S ribosomal protein L31Escherichia coli K-120.0355
50S ribosomal protein L31 type BEscherichia coli K-120.0355
50S ribosomal protein L32Escherichia coli K-120.0355
50S ribosomal protein L33Escherichia coli K-120.0355
50S ribosomal protein L34Escherichia coli K-120.0355
50S ribosomal protein L35Escherichia coli K-120.0355
50S ribosomal protein L36Escherichia coli K-120.0355
30S ribosomal protein S10Escherichia coli K-120.0355
30S ribosomal protein S11Escherichia coli K-120.0355
30S ribosomal protein S12Escherichia coli K-120.0355
30S ribosomal protein S13Escherichia coli K-120.0355
30S ribosomal protein S16Escherichia coli K-120.0355
30S ribosomal protein S18Escherichia coli K-120.0355
30S ribosomal protein S19Escherichia coli K-120.0355
30S ribosomal protein S20Escherichia coli K-120.0355
30S ribosomal protein S2Escherichia coli K-120.0355
30S ribosomal protein S3Escherichia coli K-120.0355
30S ribosomal protein S4Escherichia coli K-120.0355
30S ribosomal protein S5Escherichia coli K-120.0355
30S ribosomal protein S8Escherichia coli K-120.0355
30S ribosomal protein S9Escherichia coli K-120.0355
50S ribosomal protein L13Escherichia coli K-120.0355
50S ribosomal protein L14Escherichia coli K-120.0355
50S ribosomal protein L16Escherichia coli K-120.0355
50S ribosomal protein L23Escherichia coli K-120.0355
30S ribosomal protein S15Escherichia coli K-120.0355
50S ribosomal protein L17Escherichia coli K-120.0355
50S ribosomal protein L21Escherichia coli K-120.0355
50S ribosomal protein L30Escherichia coli K-120.0355
50S ribosomal protein L6Escherichia coli K-120.0355
30S ribosomal protein S14Escherichia coli K-120.0355
30S ribosomal protein S17Escherichia coli K-120.0355
30S ribosomal protein S1Escherichia coli K-120.0355
50S ribosomal protein L18Escherichia coli K-120.0355
50S ribosomal protein L2Escherichia coli K-120.0355
50S ribosomal protein L3Escherichia coli K-120.0355
50S ribosomal protein L24Escherichia coli K-120.0355
50S ribosomal protein L4Escherichia coli K-120.0355
50S ribosomal protein L22Escherichia coli K-120.0355
50S ribosomal protein L5Escherichia coli K-120.0355
30S ribosomal protein S21Escherichia coli K-120.0355
50S ribosomal protein L25Escherichia coli K-120.0355
50S ribosomal protein L36 2Escherichia coli K-120.0355

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's3 (21.43)18.2507
2000's6 (42.86)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McCammon, JA; Tor, Y; Trylska, J; Yang, G1
Inaoka, T; Ochi, K; Okamoto, S; Wang, G1
Aboul-ela, F; Allam, K; Bodoor, K; Boisdore, M; Boyapati, V; Gopu, V; Miller, J; Treleaven, WD; Weldeghiorghis, T1
Martinelli, SD; Sheikh, A1
Burke, JF; Mogg, AE1
Crouzet, M; Grant, CM; Izgu, F; Tuite, MF1
Buchanan, JH; Sidhu, J; Stevens, A1
Buchanan, JH; Sidhu, J1
Wang, AL; Wang, CC; Yu, DC1
Balakrishnan, R; Griffiths, JK; Tzipori, S; Widmer, G1
Bedwell, DM; Keeling, K; Manuvakhova, M1
Chun, HH; Du, L; Gamo, KM; Gatti, RA; Lai, CH; Mitui, M; Nahas, SA1
Barbieri, CM; Kaul, M; Pilch, DS1
Baba, F; Kanazawa, H; Koganei, M; Kondo, J1

Other Studies

14 other study(ies) available for antibiotic g 418 and paromomycin

ArticleYear
Binding of aminoglycosidic antibiotics to the oligonucleotide A-site model and 30S ribosomal subunit: Poisson-Boltzmann model, thermal denaturation, and fluorescence studies.
    Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18

    Topics: Aminoglycosides; Anti-Bacterial Agents; Binding Sites; Fluorescence; Nucleic Acid Denaturation; Oligonucleotides; Ribosomes; RNA, Ribosomal, 16S; Static Electricity; Thermodynamics

2006
A novel insertion mutation in Streptomyces coelicolor ribosomal S12 protein results in paromomycin resistance and antibiotic overproduction.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Amino Acid Substitution; Anti-Bacterial Agents; Cell-Free System; DNA, Bacterial; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Glycine; Green Fluorescent Proteins; Microbial Sensitivity Tests; Molecular Structure; Mutagenesis, Insertional; Paromomycin; Protein Biosynthesis; Ribosomal Proteins; RNA, Bacterial; Sequence Analysis, DNA; Streptomyces coelicolor

2009
Design and implementation of an ribonucleic acid (RNA) directed fragment library.
    Journal of medicinal chemistry, 2009, Jun-25, Volume: 52, Issue:12

    Topics: Binding Sites; Chemistry, Physical; Databases, Factual; Drug Design; Ligands; Magnetic Resonance Spectroscopy; Molecular Weight; Organic Chemicals; Quality Control; RNA; Small Molecule Libraries

2009
Hygromycin- and paromomycin-resistant mutants of Aspergillus nidulans alter translational fidelity.
    Current genetics, 1991, Volume: 20, Issue:3

    Topics: Aspergillus nidulans; Drug Resistance, Microbial; Genes, Fungal; Gentamicins; Hygromycin B; Mutation; Paromomycin; Phenotype; Protein Biosynthesis

1991
Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromomycin.
    Nucleic acids research, 1985, Sep-11, Volume: 13, Issue:17

    Topics: Acetyltransferases; Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Chlorocebus aethiops; DNA Restriction Enzymes; Gentamicins; Kidney; Kinetics; Mutation; Paromomycin; Plasmids; Suppression, Genetic; Transfection

1985
The allosuppressor gene SAL4 encodes a protein important for maintaining translational fidelity in Saccharomyces cerevisiae.
    Current genetics, 1988, Volume: 14, Issue:6

    Topics: Anti-Bacterial Agents; Blotting, Northern; Blotting, Southern; Cycloheximide; DNA Probes; DNA, Fungal; Fungal Proteins; Genes, Fungal; Gentamicins; Hygromycin B; Nucleic Acid Hybridization; Paromomycin; Phenotype; Protein Biosynthesis; Restriction Mapping; RNA, Fungal; Saccharomyces cerevisiae; Suppression, Genetic

1988
Aminoglycoside antibiotic treatment of human fibroblasts: intracellular accumulation, molecular changes and the loss of ribosomal accuracy.
    European journal of cell biology, 1987, Volume: 43, Issue:1

    Topics: Anti-Bacterial Agents; Biological Transport; Cell Line; Endocytosis; Fibroblasts; Gentamicins; Humans; Kinetics; Paromomycin; Proteins; Ribosomes

1987
Autofluorescence and ageing: changes in ribosome accuracy and lysosome [corrected] function.
    Mechanisms of ageing and development, 1986, Nov-14, Volume: 36, Issue:3

    Topics: Aging; Anti-Bacterial Agents; Cell Line; Feedback; Fluorescence; Gentamicins; Humans; Lysosomes; Mitosis; Paromomycin; Ribosomes; Streptomycin

1986
Stable coexpression of a drug-resistance gene and a heterologous gene in an ancient parasitic protozoan Giardia lamblia.
    Molecular and biochemical parasitology, 1996, Dec-02, Volume: 83, Issue:1

    Topics: Amebicides; Animals; Anti-Bacterial Agents; Cloning, Molecular; Drug Resistance; Gene Expression; Genes, Protozoan; Genes, Reporter; Genetic Vectors; Gentamicins; Giardia lamblia; Giardiavirus; Kanamycin Kinase; Luciferases; Paromomycin; Phosphotransferases (Alcohol Group Acceptor); Transformation, Genetic

1996
Paromomycin and geneticin inhibit intracellular Cryptosporidium parvum without trafficking through the host cell cytoplasm: implications for drug delivery.
    Infection and immunity, 1998, Volume: 66, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Caco-2 Cells; Cattle; Cell Division; Cell Line; Cell Line, Transformed; Coccidiostats; Cryptosporidium parvum; Cytoplasm; Gentamicins; Humans; Kanamycin Kinase; Paromomycin; Protein Biosynthesis; Tritium

1998
Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system.
    RNA (New York, N.Y.), 2000, Volume: 6, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Cinnamates; Codon, Terminator; Dose-Response Relationship, Drug; Escherichia coli; Genes, Reporter; Gentamicins; Humans; Hygromycin B; Kanamycin; Neomycin; Paromomycin; Plasmids; Protein Biosynthesis; Rabbits; Reticulocytes; Ribosomes; RNA, Messenger; Sisomicin; Streptomycin; Tobramycin

2000
Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Nov-02, Volume: 101, Issue:44

    Topics: Aminoglycosides; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Base Sequence; Cell Cycle Proteins; Cell Line; Codon, Nonsense; DNA; DNA-Binding Proteins; Gentamicins; Humans; In Vitro Techniques; Paromomycin; Point Mutation; Protein Serine-Threonine Kinases; Radiation Tolerance; Tobramycin; Tumor Suppressor Proteins

2004
Defining the basis for the specificity of aminoglycoside-rRNA recognition: a comparative study of drug binding to the A sites of Escherichia coli and human rRNA.
    Journal of molecular biology, 2005, Feb-11, Volume: 346, Issue:1

    Topics: Aminoglycosides; Base Sequence; Binding Sites; Calorimetry; Escherichia coli; Gentamicins; Humans; Hydrogen-Ion Concentration; Models, Molecular; Nucleic Acid Conformation; Paromomycin; Protein Structure, Tertiary; Protons; RNA, Ribosomal; Spectrometry, Fluorescence; Static Electricity; Substrate Specificity; Temperature; Thermodynamics; Time Factors; Titrimetry

2005
A structural basis for the antibiotic resistance conferred by an N1-methylation of A1408 in 16S rRNA.
    Nucleic acids research, 2017, Dec-01, Volume: 45, Issue:21

    Topics: Adenosine; Aminoglycosides; Binding Sites; Drug Resistance, Bacterial; Gentamicins; Methylation; Models, Molecular; Mutation; Paromomycin; RNA, Bacterial; RNA, Ribosomal, 16S

2017