antibiotic-1233a and mevalonolactone

antibiotic-1233a has been researched along with mevalonolactone* in 1 studies

Other Studies

1 other study(ies) available for antibiotic-1233a and mevalonolactone

Article	Year
Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase. The Journal of antibiotics, 1992, Volume: 45, Issue:7 Simple and efficient syntheses of 1233A analogs were developed and the inhibitory activity of the analogs against hydroxymethylglutaryl coenzyme A (HMG-CoA) synthase was determined. Study of the structure-activity relationships revealed that not only the geometry in beta-lactone moiety but also the length of the carbon side chain is important for inhibitory activity against HMG-CoA synthase. Topics: Animals; Fatty Acids, Unsaturated; Hydroxymethylglutaryl-CoA Synthase; Lactones; Mevalonic Acid; Microbial Sensitivity Tests; Vero Cells	1992

Article

Year

Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase.

The Journal of antibiotics, 1992, Volume: 45, Issue:7

Simple and efficient syntheses of 1233A analogs were developed and the inhibitory activity of the analogs against hydroxymethylglutaryl coenzyme A (HMG-CoA) synthase was determined. Study of the structure-activity relationships revealed that not only the geometry in beta-lactone moiety but also the length of the carbon side chain is important for inhibitory activity against HMG-CoA synthase.

Topics: Animals; Fatty Acids, Unsaturated; Hydroxymethylglutaryl-CoA Synthase; Lactones; Mevalonic Acid; Microbial Sensitivity Tests; Vero Cells

1992