antalarmin has been researched along with r 121919 in 11 studies
| Studies (antalarmin) | Trials (antalarmin) | Recent Studies (post-2010) (antalarmin) | Studies (r 121919) | Trials (r 121919) | Recent Studies (post-2010) (r 121919) |
|---|---|---|---|---|---|
| 181 | 0 | 76 | 83 | 4 | 32 |
| Protein | Taxonomy | antalarmin (IC50) | r 121919 (IC50) |
|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Homo sapiens (human) | 0.0321 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (72.73) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bozigian, H; Chen, TK; Dyck, B; Grigoriadis, DE; Gross, RS; Guo, Z; Haddach, M; Marinkovic, D; McCarthy, JR; Moorjani, M; Regan, CF; Saunders, J; Schwaebe, MK; Szabo, T; Williams, JP; Zhang, X | 1 |
| Chen, TK; Crowe, PD; Dyck, B; Grey, J; Grigoriadis, DE; Gross, RS; Guo, Z; Haddach, M; Kiankarimi, M; Lanier, M; Li, BF; Luo, Z; McCarthy, JR; Moorjani, M; Saunders, J; Sullivan, R; Tellew, JE; Williams, JP; Zamani-Kord, S; Zhang, X | 1 |
| Carey, GJ; Gold, LH; Nielsen, DM | 1 |
| Houshyar, H; Hsin, LW; Jutkiewicz, EM; Rice, KC; Wood, SK; Woods, JH | 1 |
| Ganesh, A; Grigoriadis, DE; Hale, L; Kiddoo, DA; Leiser, SC; Valentino, RJ; Zderic, S | 1 |
| Fischbach, PS; Rice, KC; Savit, AZ; Verhoeven, RE; Wood, SK; Woods, JH | 1 |
| Funk, CK; Koob, GF; Lee, MJ; Rice, KC; Zorrilla, EP | 1 |
| Cottone, P; Koob, GF; Lee, MJ; Rice, KC; Sabino, V; Steardo, L; Zorrilla, EP | 1 |
| Justice, NJ; Lee, AR; Rice, KC; Rissman, RA; Sawchenko, PE; Staup, MA; Vale, W | 1 |
| Akhtar, S; Csernansky, JG; Dong, H; Li, F; Meltzer, HY; Montalvo-Ortiz, J; Rice, KC; Shi, J; Tucker, C; Wang, S; Zeng, Z | 1 |
| Csernansky, J; Dong, H; Gallardo, C; Hong, E; Keegan, JM; Montalvo-Ortiz, J; Rice, KC; Wang, B | 1 |
11 other study(ies) available for antalarmin and r 121919
| Article | Year |
|---|---|
Potent, orally active corticotropin-releasing factor receptor-1 antagonists containing a tricyclic pyrrolopyridine or pyrazolopyridine core.
Topics: Acenaphthenes; Adrenocorticotropic Hormone; Animals; Biological Availability; Blood-Brain Barrier; Cells, Cultured; Cyclic AMP; Heterocyclic Compounds, 3-Ring; Humans; In Vitro Techniques; Male; Mice; Pituitary Gland; Pyrazoles; Pyridines; Pyrroles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Structure-Activity Relationship | 2005 |
Design and synthesis of tricyclic imidazo[4,5-b]pyridin-2-ones as corticotropin-releasing factor-1 antagonists.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Animals; Blood-Brain Barrier; CHO Cells; Corticotropin-Releasing Hormone; Cricetinae; Cricetulus; Cyclic AMP; Drug Design; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Injections, Intravenous; Male; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stereoisomerism; Structure-Activity Relationship | 2005 |
Antidepressant-like activity of corticotropin-releasing factor type-1 receptor antagonists in mice.
Topics: Animals; Antidepressive Agents; Clorgyline; Desipramine; Dose-Response Relationship, Drug; Fluoxetine; Hindlimb Suspension; Male; Mice; Morpholines; Motor Activity; Paroxetine; Pyrazoles; Pyrimidines; Pyrroles; Reboxetine; Receptors, Corticotropin-Releasing Hormone; Selegiline; Swimming; Tranylcypromine; Triazines | 2004 |
The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919, in the forced swim test and on swim-induced increases in adrenocorticotropin in rats.
Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Psychological; Swimming; Triazoles | 2005 |
Impact of state of arousal and stress neuropeptides on urodynamic function in freely moving rats.
Topics: Animals; Arousal; Corticotropin-Releasing Hormone; Electroencephalography; Hormone Antagonists; Injections, Spinal; Male; Movement; Neuropeptides; Peptide Fragments; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Sleep; Urocortins; Urodynamics; Wakefulness | 2006 |
Facilitation of cardiac vagal activity by CRF-R1 antagonists during swim stress in rats.
Topics: Animals; Bradycardia; Cholinergic Antagonists; Corticotropin-Releasing Hormone; Death, Sudden, Cardiac; Disease Models, Animal; Exercise Tolerance; Fatigue; Heart Rate; Hypothalamo-Hypophyseal System; Hypothermia, Induced; Male; Mifepristone; Peptide Fragments; Psychomotor Agitation; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Swimming; Vagus Nerve; Vagus Nerve Diseases | 2006 |
Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats.
Topics: Alcoholism; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Operant; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Hormone Antagonists; Male; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Self Administration; Triazines | 2007 |
Dissociation between opioid and CRF1 antagonist sensitive drinking in Sardinian alcohol-preferring rats.
Topics: Alcohol Drinking; Animals; Behavior, Addictive; Central Nervous System Agents; Drinking; Ethanol; Male; Naltrexone; Narcotic Antagonists; Pyrimidines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Corticotropin-Releasing Hormone; Reinforcement, Psychology; Self Administration; Stress, Psychological; Triazines | 2006 |
Corticotropin-releasing factor receptor-dependent effects of repeated stress on tau phosphorylation, solubility, and aggregation.
Topics: Animals; Blotting, Western; Dentate Gyrus; Detergents; Female; Fluorescent Antibody Technique; Green Fluorescent Proteins; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Immunoelectron; Neurons; Phosphorylation; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Solubility; Stress, Psychological; tau Proteins | 2012 |
Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Hippocampus; Male; Memory; Mice; Mice, Transgenic; Neurons; Plaque, Amyloid; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Signal Transduction | 2014 |
Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats.
Topics: Age Factors; Animals; Anxiety; Behavior; Behavior, Animal; Corticotropin-Releasing Hormone; Depression; Disease Models, Animal; Female; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Synapses | 2018 |