anpirtoline has been researched along with piperidines in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 6 (19.35) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldberg, SR; Nickel, B; Shannon, HE; Swedberg, MD | 1 |
| Barnes, NM; Costall, B; Gozlan, H; Hamon, M; Kelly, ME; Metzenauer, P; Murphy, DA; Naylor, RJ | 1 |
| Göthert, M; Gozlan, H; Hamon, M; Nickel, B; Schlicker, E; Szelenyi, I; Werner, U | 1 |
| Barann, M; Bönisch, H; Göthert, M; Gozlan, H; Hamon, M; Laguzzi, R; Metzenauer, P; Nickel, B; Szelenyi, I | 1 |
| Friedel, I; Hummel, C; Hummel, T; Kobal, G; Pauli, E | 1 |
| O'Neill, MF; Parameswaran, T | 1 |
| Cook, DF; Wirtshafter, D | 1 |
| Hezký, P; Krejcí, I; Proska, J; Rádl, S | 3 |
| Ahlenius, S; Hillegaart, V | 1 |
| Bourin, M; Redrobe, JP | 1 |
| Hezky, P; Königová, O; Kovárová, L; Krejcí, I; Proska, J; Rádl, S; Vosátka, V | 1 |
| Dulawa, SC; Geyer, MA; Gross, C; Hen, R; Stark, KL | 1 |
| Hejnová, L; Hezky, P; Krejcí, I; Proska, J; Rádl, S | 1 |
| Ahlenius, S; Kaur, P | 1 |
| Conway, MW; O'Neill, MF | 1 |
| Jähkel, M; Oehler, J; Rilke, O; Will, K | 1 |
| de Almeida, RM; Miczek, KA | 2 |
| De Almeida, RM; De Bold, JF; Fish, EW; Miczek, KA | 1 |
| Ahlander-Lüttgen, M; Madjid, N; Ogren, SO; Sandin, J; Schött, PA | 1 |
| Diksic, M; Nakai, A; Nguyen, KQ; Tohyama, Y; Watanabe, A | 1 |
| Bourin, M; Chenu, F; David, DJ; Gardier, AM; Le Maître, E; Leroux-Nicollet, I | 1 |
| Chen, L; Li, X; Salinas, GD | 1 |
| Che, CT; Huang, Z; Ip, SP; Mao, QQ; Xian, YF | 1 |
| Beaulieu, JM; Chen, L; Gamble, KL; Li, F; Li, X; Paul, J; Sampson, K; Woodgett, JR; Yang, S; Zhou, W | 1 |
| Aldegunde, M; Ceballos, FC; Mancebo, MJ; Pérez-Maceira, J | 1 |
| Bézard, E; Björklund, A; Carta, M; Li, Q; Muñoz, A; Pioli, EY; Porras, G; Tronci, E | 1 |
| Aldegunde, M; Mancebo, MJ; Pérez Maceira, JJ | 1 |
| Bracha, S; Chappell, PE; Goodall, CP; Marley, K; Stang, B; Viall, AK | 1 |
1 review(s) available for anpirtoline and piperidines
| Article | Year |
|---|---|
Social and neural determinants of aggressive behavior: pharmacotherapeutic targets at serotonin, dopamine and gamma-aminobutyric acid systems.
Topics: Adaptation, Psychological; Aggression; Animals; Brain; Dopamine; Ethanol; gamma-Aminobutyric Acid; Gonadal Steroid Hormones; Humans; Oxazolidinones; Piperidines; Pregnanolone; Pyridines; Receptors, Dopamine; Receptors, GABA; Receptors, Serotonin; Reinforcement Schedule; Serotonin; Serotonin Receptor Agonists; Social Environment; Tryptamines | 2002 |
1 trial(s) available for anpirtoline and piperidines
| Article | Year |
|---|---|
A comparison of the antinociceptive effects of imipramine, tramadol and anpirtoline.
Topics: Administration, Oral; Adult; Analgesia; Analgesics; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Evoked Potentials, Somatosensory; Female; Humans; Imipramine; Male; Piperidines; Pyridines; Tramadol | 1994 |
29 other study(ies) available for anpirtoline and piperidines
| Article | Year |
|---|---|
D-16949 (anpirtoline): a novel serotonergic (5-HT1B) psychotherapeutic agent assessed by its discriminative effects in the rat.
Topics: Animals; Antidepressive Agents; Dextroamphetamine; Discrimination Learning; Male; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred F344; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1992 |
Anxiolytic-like actions of anpirtoline in a mouse light-dark aversion paradigm.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Brain; Cell Membrane; Cerebral Cortex; Corpus Striatum; Darkness; Exploratory Behavior; Hippocampus; Light; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperidines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin | 1992 |
Anpirtoline, a novel, highly potent 5-HT1B receptor agonist with antinociceptive/antidepressant-like actions in rodents.
Topics: Adenylyl Cyclase Inhibitors; Analgesics; Animals; Antidepressive Agents; Brain Chemistry; Electric Stimulation; Female; In Vitro Techniques; Male; Mice; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Social Behavior; Social Isolation; Swine | 1992 |
5-HT3 receptor antagonism by anpirtoline, a mixed 5-HT1 receptor agonist/5-HT3 receptor antagonist.
Topics: Animals; Antidepressive Agents; Antiemetics; Brain Neoplasms; Cisplatin; Entorhinal Cortex; In Vitro Techniques; Male; Mice; Neuroblastoma; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Reflex; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swine; Tumor Cells, Cultured | 1995 |
RU24969-induced behavioural syndrome requires activation of both 5HT1A and 5HT1B receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Indoles; Male; Motor Activity; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 1997 |
Serotonin-1B agonists induce compartmentally organized striatal Fos expression in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Corpus Striatum; Immunohistochemistry; Indoles; Male; Nerve Tissue Proteins; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Analgetically active substances derived from structures of anpirtoline and epibatidine.
Topics: Analgesics, Non-Narcotic; Animals; Bridged Bicyclo Compounds, Heterocyclic; Drug Design; Mice; Molecular Conformation; Piperidines; Pyridines; Structure-Activity Relationship; Thermodynamics | 1998 |
Facilitation and inhibition of male rat ejaculatory behaviour by the respective 5-HT1A and 5-HT1B receptor agonists 8-OH-DPAT and anpirtoline, as evidenced by use of the corresponding new and selective receptor antagonists NAD-299 and NAS-181.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Benzopyrans; Ejaculation; Female; Male; Morpholines; Pindolol; Piperidines; Propanolamines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Time Factors | 1998 |
Synthesis and analgesic activity of some deaza derivatives of anpirtoline.
Topics: Analgesics, Non-Narcotic; Animals; Escape Reaction; Hippocampus; In Vitro Techniques; Male; Mice; Pain Measurement; Piperidines; Pyridines; Radioligand Assay; Rats; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1999 |
Evidence of the activity of lithium on 5-HT1B receptors in the mouse forced swimming test: comparison with carbamazepine and sodium valproate.
Topics: Animals; Antimanic Agents; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Lithium; Mice; Motor Activity; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin Receptor Agonists; Swimming; Valproic Acid | 1999 |
Synthesis and analgesic activity of some condensed analogs of anpirtoline.
Topics: Analgesics; Animals; Male; Mice; Piperidines; Pyridines; Rats | 1999 |
Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Female; Habituation, Psychophysiologic; Indoles; Mice; Mice, Knockout; Neural Inhibition; Piperazines; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Serotonin Receptor Agonists | 2000 |
Synthesis and analgesic activity of some side-chain modified anpirtoline derivatives.
Topics: Analgesics; Animals; Binding, Competitive; Brain; Male; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Pain Measurement; Piperidines; Protein Binding; Pyridines; Pyrrolidines; Rats; Receptors, Serotonin | 2000 |
Non-serotonergic potentiation by (-)-pindolol of DOI-induced forward locomotion in rats: possible involvement of beta-adrenoceptors?.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Betaxolol; Biogenic Monoamines; Dihydroxyphenylalanine; Drug Synergism; Indophenol; Male; Motor Activity; Pindolol; Piperazines; Piperidines; Propanolamines; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reserpine; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Synthesis and analgesic activity of some quinazoline analogs of anpirtoline.
Topics: Aminopyridines; Analgesics; Animals; Hot Temperature; Male; Mice; Mice, Inbred Strains; Molecular Structure; Pain; Piperidines; Pyridines; Quinazolines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Structure-Activity Relationship; Tramadol | 2000 |
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Indoles; Mice; Mice, Inbred Strains; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 2001 |
Behavioral and neurochemical effects of anpirtoline and citalopram in isolated and group housed mice.
Topics: Aggression; Animals; Citalopram; Dopamine; Housing, Animal; Male; Mice; Piperidines; Pyridines; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Social Behavior; Social Isolation | 2001 |
Oral drug self-administration in the home cage of mice: alcohol-heightened aggression and inhibition by the 5-HT1B agonist anpirtoline.
Topics: Aggression; Alcohol Drinking; Animals; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Receptor Agonists | 2001 |
Aggression escalated by social instigation or by discontinuation of reinforcement ("frustration") in mice: inhibition by anpirtoline: a 5-HT1B receptor agonist.
Topics: Aggression; Animals; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Extinction, Psychological; Frustration; Male; Mice; Mice, Inbred Strains; Neural Inhibition; Neurons; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reinforcement, Psychology; Serotonin; Serotonin Receptor Agonists; Social Behavior; Synaptic Transmission | 2002 |
Analysis of the role of the 5-HT1B receptor in spatial and aversive learning in the rat.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzopyrans; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Escape Reaction; Male; Maze Learning; Morpholines; Motor Activity; Muscarinic Antagonists; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Retention, Psychology; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Space Perception; Swimming | 2003 |
Effects of anpirtoline on regional serotonin synthesis in the rat brain: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Dose-Response Relationship, Drug; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 2006 |
Serotonin1B heteroreceptor activation induces an antidepressant-like effect in mice with an alteration of the serotonergic system.
Topics: 5,7-Dihydroxytryptamine; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Citalopram; Dopamine; Male; Mice; Oxadiazoles; Piperazines; Piperidines; Pyridines; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2008 |
Regulation of serotonin 1B receptor by glycogen synthase kinase-3.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Benzazepines; Cell Line; CHO Cells; Cholera Toxin; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Glycogen Synthase Kinase 3; Humans; Indoles; Male; Maleimides; Mice; Mice, Inbred BALB C; Oxadiazoles; Oximes; Piperidines; Piperidones; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, Serotonin, 5-HT1B; Roscovitine; Serotonin; Spiro Compounds | 2009 |
Role of 5-HT(1A) and 5-HT(1B) receptors in the antidepressant-like effect of piperine in the forced swim test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Aminopyridines; Animals; Antidepressive Agents; Benzodioxoles; Data Interpretation, Statistical; Male; Methiothepin; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Swimming | 2011 |
The effects of glycogen synthase kinase-3beta in serotonin neurons.
Topics: Analysis of Variance; Animals; Brain; Chromatography, High Pressure Liquid; Cyclic AMP; Fluorescent Antibody Technique; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Mice; Mice, Knockout; Motor Activity; Piperidines; Pyridines; Raphe Nuclei; Receptor, Serotonin, 5-HT1B; Serotonergic Neurons; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2012 |
Hypothalamic neuropeptide Y (NPY) gene expression is not affected by central serotonin in the rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Dexfenfluramine; Feeding Behavior; Gene Expression Regulation; Hypothalamus; Injections, Intraperitoneal; Neuropeptide Y; Oncorhynchus mykiss; Piperidines; Pyridines; RNA, Messenger; Serotonin | 2013 |
Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia.
Topics: Animals; Antiparkinson Agents; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Parkinsonian Disorders; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists | 2013 |
The involvement of 5-HT-like receptors in the regulation of food intake in rainbow trout (Oncorhynchus mykiss).
Topics: Animals; Eating; Oncorhynchus mykiss; Piperidines; Pyridines; Receptors, Serotonin; Serotonin Receptor Agonists | 2014 |
Antagonism of serotonin receptor 1B decreases viability and promotes apoptosis in the COS canine osteosarcoma cell line.
Topics: Animals; Apoptosis; Cell Survival; Cyclic AMP Response Element-Binding Protein; Dog Diseases; Dogs; Extracellular Signal-Regulated MAP Kinases; Osteosarcoma; Piperidines; Piperidones; Pyridines; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Signal Transduction; Spiro Compounds; Taurine; Thiadiazines | 2016 |