anordiol has been researched along with acetazolamide in 1 studies
*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]
*Acetazolamide: One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) [MeSH]
| Studies (anordiol) | Trials (anordiol) | Recent Studies (post-2010) (anordiol) | Studies (acetazolamide) | Trials (acetazolamide) | Recent Studies (post-2010) (acetazolamide) |
|---|---|---|---|---|---|
| 23 | 0 | 1 | 7,604 | 495 | 1,521 |
| Protein | Taxonomy | anordiol (IC50) | acetazolamide (IC50) |
|---|---|---|---|
| Chain A, Class Iii Chitinase Chia1 | Aspergillus fumigatus A1163 | 164 | |
| Carbonic anhydrase 12 | Homo sapiens (human) | 0.3178 | |
| Renin | Homo sapiens (human) | 8.2 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 2.3173 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 1.2619 | |
| Carbonic anhydrase 2 | Bos taurus (cattle) | 0.7 | |
| Carbonic anhydrase 3 | Homo sapiens (human) | 1.95 | |
| Cathepsin B | Bos taurus (cattle) | 0.02 | |
| Steryl-sulfatase | Homo sapiens (human) | 0.025 | |
| Carbonic anhydrase 4 | Homo sapiens (human) | 0.1216 | |
| Carbonic anhydrase 6 | Homo sapiens (human) | 0.2925 | |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | 0.1763 | |
| Carbonic anhydrase 7 | Homo sapiens (human) | 1.1737 | |
| Carbonic anhydrase 9 | Homo sapiens (human) | 0.464 | |
| Renin | Macaca mulatta (Rhesus monkey) | 8.2 | |
| Carbonic anhydrase 13 | Homo sapiens (human) | 0.23 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.07 | |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | 0.77 | |
| Carbonic anhydrase 14 | Homo sapiens (human) | 0.183 | |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | 0.23 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, T; Li, XJ; Ma, B; Mu, SM; Xiang, Y; Yu, HM | 1 |
1 other study(ies) available for anordiol and acetazolamide
| Article | Year |
|---|---|
Effects of acetazolamide and anordiol on osmotic water permeability in AQP1-cRNA injected Xenopus oocyte.
Topics: Acetazolamide; Animals; Aquaporin 1; Aquaporins; Carbonic Anhydrase Inhibitors; Cell Membrane Permeability; Female; Norandrostanes; Oocytes; Osmosis; RNA, Complementary; Xenopus laevis | 2004 |