Page last updated: 2024-09-05

anidulafungin and cyclosporine

anidulafungin has been researched along with cyclosporine in 4 studies

Compound Research Comparison

Studies (anidulafungin)	Trials (anidulafungin)	Recent Studies (post-2010) (anidulafungin)	Studies (cyclosporine)	Trials (cyclosporine)	Recent Studies (post-2010) (cyclosporine)
568	33	331	377	2	170
568	33	331	30,547	3,802	6,558

Protein Interaction Comparison

Protein	Taxonomy	cyclosporine (IC50)
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	0.6315
Bile salt export pump	Rattus norvegicus (Norway rat)	0.6
Bile salt export pump	Homo sapiens (human)	3.5
Interleukin-2	Mus musculus (house mouse)	0.005
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	0.7
ATP-dependent translocase ABCB1	Homo sapiens (human)	1.6792
Cytochrome P450 3A4	Homo sapiens (human)	3.734
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	5.82
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A5	Homo sapiens (human)	2.06
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	4.8
Substance-K receptor	Homo sapiens (human)	4.139
Peptidyl-prolyl cis-trans isomerase B	Homo sapiens (human)	0.0088
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A7	Homo sapiens (human)	2.06
Cytochrome P450 2C19	Homo sapiens (human)	7
Multidrug resistance-associated protein 1	Homo sapiens (human)	3.5082
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Peptidyl-prolyl cis-trans isomerase A	Homo sapiens (human)	0.0252
Peptidyl-prolyl cis-trans isomerase FKBP4	Homo sapiens (human)	0.016
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens (human)	0.183
Peptidyl-prolyl cis-trans isomerase D	Homo sapiens (human)	0.0036
Sodium/bile acid cotransporter	Homo sapiens (human)	1
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.455
Cytochrome P450 3A43	Homo sapiens (human)	2.06
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Mus musculus (house mouse)	0.57
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	4.3
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	0.95

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (50.00)	29.6817
2010's	1 (25.00)	24.3611
2020's	1 (25.00)	2.80

Authors

Authors	Studies
Lombardo, F; Obach, RS; Waters, NJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Byun, SY; Choi, I; Jeon, S; Kim, S; Ko, M; Lee, J; Park, S; Shum, D	1
Dowell, JA; Henkel, T; Krause, D; Stogniew, M; Weston, IE	1

Reviews

1 review(s) available for anidulafungin and cyclosporine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for anidulafungin and cyclosporine

Article	Year
Assessment of the safety and pharmacokinetics of anidulafungin when administered with cyclosporine. Journal of clinical pharmacology, 2005, Volume: 45, Issue:2 Topics: Administration, Oral; Anidulafungin; Antifungal Agents; Area Under Curve; Biological Availability; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Echinocandins; Female; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Microsomes, Liver; Peptides, Cyclic; Time Factors; Tritium	2005

Article

Year

Assessment of the safety and pharmacokinetics of anidulafungin when administered with cyclosporine.

Journal of clinical pharmacology, 2005, Volume: 45, Issue:2

Topics: Administration, Oral; Anidulafungin; Antifungal Agents; Area Under Curve; Biological Availability; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Echinocandins; Female; Humans; Injections, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Microsomes, Liver; Peptides, Cyclic; Time Factors; Tritium

2005

Other Studies

2 other study(ies) available for anidulafungin and cyclosporine

Article	Year
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs. Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7 Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells	2020

Article

Year

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.

Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008

Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs.

Antimicrobial agents and chemotherapy, 2020, 06-23, Volume: 64, Issue:7

Topics: Animals; Anti-Inflammatory Agents; Antiviral Agents; Betacoronavirus; Cell Line; Chlorocebus aethiops; Coronavirus Infections; COVID-19; Drug Evaluation, Preclinical; Drug Repositioning; Humans; Niclosamide; Pandemics; Pneumonia, Viral; Pregnenediones; SARS-CoV-2; Vero Cells

2020