Page last updated: 2024-09-05

anidulafungin and cancidas

anidulafungin has been researched along with cancidas in 41 studies

Compound Research Comparison

Studies
(anidulafungin)
Trials
(anidulafungin)
Recent Studies (post-2010)
(anidulafungin)
Studies
(cancidas)
Trials
(cancidas)
Recent Studies (post-2010) (cancidas)
56833331117124

Protein Interaction Comparison

ProteinTaxonomyanidulafungin (IC50)cancidas (IC50)
1,3-beta-D-glucan synthase catalytic subunit Candida albicans0.0002
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)6

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's31 (75.61)29.6817
2010's9 (21.95)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Jacobsen, MD; Odds, FC; Whyte, JA1
Bocanegra, R; Graybill, JR; Molina, D; Najvar, LK; Olivo, M; Wiederhold, NP1
Garcia-Effron, G; Hsu, MJ; Kahn, JN; Marr, KA; Park, S; Perlin, DS1
Balashov, S; Delmas, G; Garcia-Effron, G; Paderu, P; Park, S; Perlin, DS1
Albert, N; Chamilos, G; Kontoyiannis, DP; Lewis, RE1
Garcia-Effron, G; Park, S; Perlin, DS; Rocha, EM1
Odabasi, Z; Ostrosky-Zeichner, L; Paetznick, V; Rex, JH1
Antachopoulos, C; Meletiadis, J; Roilides, E; Sein, T; Walsh, TJ1
Chatzimoschou, A; Dalakiouridou, M; Diza-Mataftsi, E; Katragkou, A; Roilides, E; Simitsopoulou, M; Tsantali, C1
Alastruey-Izquierdo, A; Almirante, B; Cuenca-Estrella, M; Gomez-Lopez, A; Pahissa, A; Rodriguez, D; Rodriguez-Tudela, JL1
Chapman, SW; Cleary, JD; Garcia-Effron, G; Perlin, DS1
Jacobson, MJ; Nguyen, G; Patel, R; Piper, KE; Steckelberg, JM1
Lombardo, F; Obach, RS; Waters, NJ1
Edlind, TD; Garcia-Effron, G; Katiyar, SK; Park, S; Perlin, DS1
Damle, B; Dowell, J; Stogniew, M1
Chu, CC; Hsueh, PR; Ruan, SY1
Alastruey-Izquierdo, A; Castelli, MV; Cuenca-Estrella, M; Cuesta, I; Mellado, E; Monzon, A; Rodriguez-Tudela, JL1
Lewis, JS; Patterson, TF; Thompson, GR; Vallor, AC; Villareal, NC; Wiederhold, NP1
Garcia-Effron, G; Grabinski, JL; Lee, SA; Perlin, DS; Wiederhold, NP1
Garcia-Effron, G; Kontoyiannis, DP; Lewis, RE; Perlin, DS1
Garcia-Effron, G; Park, S; Perlin, DS1
Alspaugh, JA; Fortwendel, JR; Juvvadi, PR; Perfect, BZ; Perfect, JR; Pinchai, N; Steinbach, WJ1
Alastruey-Izquierdo, A; Cuenca-Estrella, M; Lass-Flörl, C; Perkhofer, S; Rodriguez-Tudela, JL1
Arendrup, MC; Bruun, B; Buzina, W; Garcia-Effron, G; Jensen, HE; Lass-Flörl, C; Lundin, C; Mortensen, KL; Perlin, DS; Reiter, N1
Dimopoulos, G; Falagas, ME; Velegraki, A1
Buitrago, MJ; Cuenca-Estrella, M; Gomez-Lopez, A; Mellado, E; Monzon, A; Rodriguez-Tudela, JL1
Jacobson, MJ; Patel, R; Piper, KE; Steckelberg, JM; Steckelberg, KE1
Cantón, E; Espinel-Ingroff, A; Gobernado, M; Pemán, J; Valentín, A1
Cleary, JD; Garcia-Effron, G; Lee, S; Park, S; Perlin, DS1
Chittick, P; Delashmitt, B; Evans, J; Palavecino, EL; Peacock, JE1
Guarro, J; Mariné, M; Pastor, FJ; Pontón, J; Quindós, G; Sahand, IH1
Canton, E; Espinel-Ingroff, A; Martín-Mazuelo, E; Peman, J1
Badali, H; De Hoog, GS; Illnait-Zaragozi, MT; Meis, JF; Najafzadeh, MJ1
Cantón, E; del Castillo, L; Espinel-Ingroff, A; Pemán, J1
Bonilla, H; Chua, DJ; DiPersio, J; Garcia-Effron, G; Ghannoum, M; Perlin, DS; Tomada, JR1
Bakker-Woudenberg, IA; Fahal, AH; van Belkum, A; van de Sande, WW1
Castanheira, M; Diekema, DJ; Jones, RN; Messer, SA; Pfaller, MA; Woosley, LN1
Andes, D; Bohrmuller, J; Diekema, DJ; Lepak, A; Marchillo, K; Pfaller, MA1
Alastruey-Izquierdo, A; Cuenca-Estrella, M; Cuesta, I; Rodriguez-Tudela, JL; Walther, G1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Liu, W; Wang, S; Yuan, L1

Reviews

2 review(s) available for anidulafungin and cancidas

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent Progress in the Discovery of Antifungal Agents Targeting the Cell Wall.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Antifungal Agents; Cell Wall; Drug Discovery; Fungi; GPI-Linked Proteins; Humans; Mannans; Mycoses; Triterpenes

2020

Other Studies

39 other study(ies) available for anidulafungin and cancidas

ArticleYear
Candida albicans and Candida dubliniensis respond differently to echinocandin antifungal agents in vitro.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Anidulafungin; Antifungal Agents; Candida; Candida albicans; Caspofungin; Echinocandins; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Peptides, Cyclic

2007
In vivo efficacy of anidulafungin and caspofungin against Candida glabrata and association with in vitro potency in the presence of sera.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Anidulafungin; Animals; Antifungal Agents; Candida glabrata; Candidiasis; Caspofungin; Echinocandins; Lipopeptides; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Peptides, Cyclic; Serum

2007
Acquired echinocandin resistance in a Candida krusei isolate due to modification of glucan synthase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5

    Topics: Amino Acid Sequence; Anidulafungin; Antifungal Agents; Candida; Caspofungin; Drug Resistance, Fungal; Echinocandins; Glucosyltransferases; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Molecular Sequence Data; Peptides, Cyclic; Protein Subunits

2007
Serum differentially alters the antifungal properties of echinocandin drugs.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Anidulafungin; Animals; Antifungal Agents; Aspergillus fumigatus; Candida albicans; Caspofungin; Drug Interactions; Drug Resistance, Fungal; Echinocandins; Glucosyltransferases; Humans; Lipopeptides; Lipoproteins; Micafungin; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Peptides, Cyclic; Serum

2007
Paradoxical effect of Echinocandins across Candida species in vitro: evidence for echinocandin-specific and candida species-related differences.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Antifungal Agents; Candida; Candidiasis; Culture Media; Fungemia; Humans; Microbial Sensitivity Tests; Neoplasms; Peptides, Cyclic; Species Specificity

2007
A Ser678Pro substitution in Fks1p confers resistance to echinocandin drugs in Aspergillus fumigatus.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Amino Acid Sequence; Amino Acid Substitution; Aspergillus fumigatus; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Glucosyltransferases; Molecular Sequence Data; Proline; Sequence Homology, Amino Acid; Serine

2007
Effects of serum on in vitro susceptibility testing of echinocandins.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Anidulafungin; Aspergillus; Candida; Caspofungin; Echinocandins; Humans; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Protein Binding; Serum

2007
Comparative in vitro pharmacodynamics of caspofungin, micafungin, and anidulafungin against germinated and nongerminated Aspergillus conidia.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Anidulafungin; Antifungal Agents; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Caspofungin; Echinocandins; Humans; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Spores, Fungal

2008
Differential activities of newer antifungal agents against Candida albicans and Candida parapsilosis biofilms.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:1

    Topics: Antifungal Agents; Azoles; Biofilms; Candida; Candida albicans; Echinocandins; Humans; Microbial Sensitivity Tests

2008
Prevalence and susceptibility profile of Candida metapsilosis and Candida orthopsilosis: results from population-based surveillance of candidemia in Spain.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: Antifungal Agents; Candida; Candidiasis; Fungemia; Humans; Microbial Sensitivity Tests; Population Surveillance; Prevalence; Spain; Species Specificity

2008
Reduced Candida glabrata susceptibility secondary to an FKS1 mutation developed during candidemia treatment.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Aged; Antifungal Agents; Candida glabrata; Candidiasis; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fatal Outcome; Female; Fungal Proteins; Fungemia; Glucosyltransferases; Humans; Lipopeptides; Membrane Proteins; Microbial Sensitivity Tests; Mutation

2008
In vitro activity of anidulafungin against Candida albicans biofilms.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6

    Topics: Anidulafungin; Antifungal Agents; Biofilms; Candida albicans; Candidiasis; Drug Resistance, Fungal; Echinocandins; Humans; Microbial Sensitivity Tests

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
A naturally occurring proline-to-alanine amino acid change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis accounts for reduced echinocandin susceptibility.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Base Sequence; Candida; Candidiasis; DNA Primers; DNA, Fungal; Drug Resistance, Fungal; Echinocandins; Enzyme Inhibitors; Fungal Proteins; Gene Expression; Genes, Fungal; Glucosyltransferases; Humans; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Species Specificity

2008
Pharmacokinetics and tissue distribution of anidulafungin in rats.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:7

    Topics: Anidulafungin; Animals; Antifungal Agents; Autoradiography; Candidiasis; Carbon Radioisotopes; Echinocandins; Humans; Infusions, Intravenous; Kidney; Liver; Lung; Male; Rats; Rats, Inbred F344; Spleen; Tissue Distribution

2008
In vitro susceptibilities of invasive isolates of Candida species: rapid increase in rates of fluconazole susceptible-dose dependent Candida glabrata isolates.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Anidulafungin; Antifungal Agents; Candida; Candida glabrata; Caspofungin; Echinocandins; Fluconazole; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole

2008
Susceptibility testing and molecular classification of Paecilomyces spp.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8

    Topics: Amphotericin B; Antifungal Agents; DNA, Fungal; DNA, Ribosomal; Echinocandins; Itraconazole; Microbial Sensitivity Tests; Paecilomyces; Phylogeny

2008
Development of caspofungin resistance following prolonged therapy for invasive candidiasis secondary to Candida glabrata infection.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Adult; Amino Acid Substitution; Antifungal Agents; Base Sequence; Candida glabrata; Candidiasis; Caspofungin; DNA Primers; DNA, Fungal; Drug Resistance, Fungal; Echinocandins; Genes, Fungal; Glucosyltransferases; Humans; Lipopeptides

2008
Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Anidulafungin; Antifungal Agents; Base Sequence; Candida albicans; Candidiasis; Caspofungin; DNA Mutational Analysis; DNA, Fungal; Drug Resistance, Fungal; Echinocandins; Genes, Fungal; Glucosyltransferases; Humans; Lipopeptides; Micafungin; Point Mutation

2008
Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:11

    Topics: Aged; Aged, 80 and over; Antifungal Agents; Candida tropicalis; Candidiasis; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fungemia; Hematologic Neoplasms; Humans; Lipopeptides; Male; Middle Aged

2008
Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1

    Topics: Anidulafungin; Candida albicans; Caspofungin; Echinocandins; Fungal Proteins; Glucosyltransferases; Lipopeptides; Micafungin; Microbial Sensitivity Tests

2009
Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Aminoglycosides; Antifungal Agents; Aspergillus fumigatus; beta-Glucans; Calcineurin; Caspofungin; Cell Wall; Chitin; Echinocandins; Fluorescent Dyes; Fungal Proteins; Genes, Fungal; Genes, ras; Lipopeptides; Microbial Sensitivity Tests; Microscopy, Fluorescence; Mutation; Signal Transduction

2009
In vitro activities of various antifungal drugs against Aspergillus terreus: Global assessment using the methodology of the European committee on antimicrobial susceptibility testing.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2

    Topics: Antifungal Agents; Aspergillosis; Aspergillus; DNA, Fungal; Humans; Microbial Sensitivity Tests; Soil Microbiology

2009
Breakthrough Aspergillus fumigatus and Candida albicans double infection during caspofungin treatment: laboratory characteristics and implication for susceptibility testing.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Candida albicans; Candidiasis; Caspofungin; Colony Count, Microbial; Echinocandins; Humans; Immunohistochemistry; Injections, Intraperitoneal; Lipopeptides; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Polymerase Chain Reaction

2009
A 10-year survey of antifungal susceptibility of candidemia isolates from intensive care unit patients in Greece.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:3

    Topics: Antifungal Agents; Candida; Candidiasis; Data Collection; Disease Susceptibility; Greece; Humans; Intensive Care Units; Microbial Sensitivity Tests; Retrospective Studies

2009
Activity profile in vitro of micafungin against Spanish clinical isolates of common and emerging species of yeasts and molds.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:5

    Topics: Acremonium; Antifungal Agents; Aspergillus; Candida; Drug Resistance, Fungal; Echinocandins; Fungi; Humans; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Mycoses; Penicillium; Scedosporium; Spain

2009
In vitro activity of micafungin against planktonic and sessile Candida albicans isolates.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:6

    Topics: Antifungal Agents; Biofilms; Candida albicans; Echinocandins; Humans; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Plankton

2009
In vitro activities of echinocandins against Candida krusei determined by three methods: MIC and minimal fungicidal concentration measurements and time-kill studies.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Anidulafungin; Antifungal Agents; Candida; Caspofungin; Echinocandins; Lipopeptides; Micafungin; Microbial Sensitivity Tests

2009
Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Antifungal Agents; Candida glabrata; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Glucosyltransferases; Reverse Transcriptase Polymerase Chain Reaction

2009
Case of fatal Blastoschizomyces capitatus infection occurring in a patient receiving empiric micafungin therapy.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Aged; Antifungal Agents; Echinocandins; Fatal Outcome; Geotrichosis; Geotrichum; Humans; Lipopeptides; Male; Micafungin; Microbial Sensitivity Tests; Neutropenia

2009
Paradoxical growth of Candida dubliniensis does not preclude in vivo response to echinocandin therapy.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Anidulafungin; Animals; Antifungal Agents; Candida; Candidiasis; Caspofungin; Echinocandins; Lipopeptides; Male; Micafungin; Mice

2009
Comparison of anidulafungin MICs determined by the clinical and laboratory standards institute broth microdilution method (M27-A3 document) and Etest for Candida species isolates.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:3

    Topics: Anidulafungin; Antifungal Agents; Candida; Caspofungin; Drug Resistance, Fungal; Echinocandins; Humans; Lipopeptides; Microbial Sensitivity Tests; Reference Standards

2010
In vitro activities of eight antifungal drugs against 55 clinical isolates of Fonsecaea spp.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4

    Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Ascomycota; Caspofungin; Chromoblastomycosis; Drug Resistance, Fungal; Echinocandins; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Lipopeptides; Microbial Sensitivity Tests; Nitriles; Pyridines; Pyrimidines; Triazoles; Voriconazole

2010
In vitro fungicidal activities of echinocandins against Candida metapsilosis, C. orthopsilosis, and C. parapsilosis evaluated by time-kill studies.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Anidulafungin; Antifungal Agents; Candida; Caspofungin; Echinocandins; In Vitro Techniques; Lipopeptides; Micafungin; Microbial Sensitivity Tests; Microbiological Techniques; Time Factors

2010
Novel FKS mutations associated with echinocandin resistance in Candida species.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5

    Topics: Adult; Antifungal Agents; Candida glabrata; Candida tropicalis; Candidiasis; Drug Resistance, Fungal; Echinocandins; Female; Glucosyltransferases; Humans; Male; Middle Aged; Mutation

2010
Madurella mycetomatis is not susceptible to the echinocandin class of antifungal agents.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Anidulafungin; Antifungal Agents; Aspergillus fumigatus; Caspofungin; Drug Resistance, Fungal; Echinocandins; Humans; In Vitro Techniques; Lipopeptides; Madurella; Micafungin; Microbial Sensitivity Tests; Mycetoma

2010
Low prevalence of fks1 hot spot 1 mutations in a worldwide collection of Candida strains.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Base Sequence; Candida; Candida albicans; Candida glabrata; Candidiasis; DNA, Fungal; Drug Resistance, Fungal; Echinocandins; Fungal Proteins; Genes, Fungal; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Sequence Homology, Amino Acid; Species Specificity

2010
In vivo comparison of the pharmacodynamic targets for echinocandin drugs against Candida species.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:6

    Topics: Anidulafungin; Animals; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candidiasis; Caspofungin; Echinocandins; Female; Kidney; Lipopeptides; Micafungin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Protein Binding; Species Specificity

2010
Antifungal susceptibility profile of human-pathogenic species of Lichtheimia.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Humans; Microbial Sensitivity Tests; Mucorales; Pyrimidines; Triazoles; Voriconazole

2010