Page last updated: 2024-09-03

anhydroecgonine methyl ester and cocaine

anhydroecgonine methyl ester has been researched along with cocaine in 48 studies

Compound Research Comparison

Studies
(anhydroecgonine methyl ester)
Trials
(anhydroecgonine methyl ester)
Recent Studies (post-2010)
(anhydroecgonine methyl ester)
Studies
(cocaine)
Trials
(cocaine)
Recent Studies (post-2010) (cocaine)
5201332,4611,0969,400

Protein Interaction Comparison

ProteinTaxonomyanhydroecgonine methyl ester (IC50)cocaine (IC50)
Amyloid-beta precursor proteinHomo sapiens (human)0.338
Fatty acid-binding protein, heartHomo sapiens (human)0.367
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0855
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0855
DRattus norvegicus (Norway rat)5.7544
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)5.7544
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)5.7544
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.2861
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.4321
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0855
Sodium-dependent serotonin transporterHomo sapiens (human)0.5442
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.8885
Sodium-dependent dopamine transporter Homo sapiens (human)0.3796
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)5.541
Sodium-dependent dopamine transporterMus musculus (house mouse)0.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)1.05
TransporterRattus norvegicus (Norway rat)3.2277

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's14 (29.17)18.2507
2000's19 (39.58)29.6817
2010's14 (29.17)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
de Zeeuw, RA; Ensing, JG; Racamy, C1
Chen, LC; Graefe, JF; Willetts, J; Wood, RW1
Chen, LC; Graefe, JF; Shojaie, J; Willetts, J; Wood, RW1
el-Fawal, HA; Wood, RW1
Cone, EJ; Darwin, WD; Hillsgrove, M1
Fang, CP; Graefe, JF; Shojaie, J; Wood, RW1
Cirimele, V; Kintz, P; Mangin, P; Sengler, C2
Chen, LC; Fang, CP; Graefe, JF; Shojaie, J; Willetts, J; Wood, RW1
Huang, L; Ishiguro, Y; Morgan, JP; Woolf, JH2
Morgan, JP; Xiao, YF1
McWhorter, LK; Paul, BD; Smith, ML1
Fandiño, AS; Kauert, G; Toennes, SW1
Bourland, JA; Hatab, MM; Hayes, EF; Kelly, RC; Sweeney, SA1
Kwong, TC; Plessinger, MA; Scheidweiler, KB; Shojaie, J; Wood, RW2
Cai, J; Ke, Q; Morgan, JP; Xiao, YF; Yang, Y1
Hodge, GD; Paul, BD; Shimomura, ET1
Andrews, AR; de Jager, LS1
Cai, J; Ke, Q; Liao, H; Morgan, JP; Xiao, YF; Yang, Y1
Fandiño, AS; Karas, M; Kauert, G; Toennes, SW1
Fandiño, AS; Kauert, GF; Toennes, SW1
Fortner, N; Johnson, BD; Liberty, HJ; Randolph, D1
Fandiño, AS; Hesse, FJ; Kauert, GF; Toennes, SW1
Bosy, T; Huestis, MA; Jacobs, AJ; Lalani, S; Paul, BD1
Bouchonnet, S; Cognard, E; Rudaz, S; Staub, C1
Callery, PS; Kraner, JC; Myers, AL; Williams, HE1
Kintz, P; Ragoucy-Sengler, C1
Hoelzle, C; Sachs, H; Scheufler, F; Thieme, D; Uhl, M1
Barnes, AJ; Brunet, BR; Huestis, MA; Mura, P; Scheidweiler, KB1
Chasin, AA; da Costa, JL; Tavares, MF; Tonin, FG; Zanolli, LA1
Bjergum, MW; Crow, FW; Langman, LJ; Williamson, CL1
Esposito, EX; Hopfinger, AJ; Shen, MY; Su, BH; Tseng, YJ1
García-Repetto, R; Giménez, MP; Martinez, MC; Soria, ML1
Abdalla, FM; Afeche, SC; Camarini, R; Carrettiero, DC; Dati, LM; de Carvalho, ND; Fukuda, S; Garcia, RC; Levada-Pires, AC; Marcourakis, T; Moura, S; Negrini-Neto, O; Sandoval, MR; Torres, LH; Yonamine, M1
Drummer, OH; Pilgrim, JL; Woodford, N1
Alvarez, JC; Bourgogne, E; Chéron, G; Miramont, S1
Dulaurent, S; Gaulier, JM; Imbert, L; Lachâtre, G; Mercerolle, M; Morichon, J1
Abdalla, FM; Afeche, SC; Camarini, R; Conn, PJ; da Costa, JL; da Silva, MA; Dati, LM; Garcia, RC; Gorjão, R; Marcourakis, T; Niswender, CM; Sandoval, MR; Torres, LH; Udo, MS; Yonamine, M1
Araújo, AM; de Melo Rodrigues, LC; Gomes, EF; Lebarch, EC; Lipaus, IFS; Martins, CW; Mendonça, JB; Nakamura-Palacios, EM; Pelição, FS1
Atkinson, S; Bailey, MJ; Costa, C; de Puit, M; Ismail, M; Palitsin, V; Webb, R1
Chen, J; Cheng, C; Oueslati, R; Wu, J1
Andreuccetti, G; Berg, T; Gjerde, H; Leyton, V; Takitane, J; Vindenes, V1
Aranguren, M; Gorlelo, JC; Krumbiegel, F; Nagel, A; Poliansky, N; Pragst, F; Rubio, NC; Thurmann, D; Zytowski, E1
Cela, R; Da Silva, KM; Estévez-Danta, A; González-Mariño, I; Quintana, JB; Rodil, R; Sodré, FF1
Gambier, N; Van Elsue, N; Warling, J; Yegles, M1
da Silva, MAA; Dal'Jovem, LF; de Oliveira Duro, S; de Souza Prates, S; Faião-Flores, F; Garcia, RCT; Marcourakis, T; Maria-Engler, SS; Udo, MSB1

Other Studies

48 other study(ies) available for anhydroecgonine methyl ester and cocaine

ArticleYear
A rapid gas chromatographic method for the fingerprinting of illicit cocaine samples.
    Journal of forensic sciences, 1992, Volume: 37, Issue:2

    Topics: Bridged Bicyclo Compounds; Chromatography, Gas; Cocaine; Cyclobutanes; Illicit Drugs; Time Factors

1992
Effects of methylecgonidine on acetylcholine-induced bronchoconstriction and indicators of lung injury in guinea pigs.
    Life sciences, 1995, Volume: 57, Issue:15

    Topics: Acetylcholine; Animals; Bronchoconstriction; Cocaine; Guinea Pigs; Injections, Subcutaneous; Lung Injury; Male; Respiration

1995
Pulmonary effects of the cocaine pyrolysis product, methylecgonidine, in guinea pigs.
    Life sciences, 1995, Volume: 56, Issue:1

    Topics: Animals; Bronchoconstriction; Cocaine; Guinea Pigs; Hot Temperature; Male

1995
Airway smooth muscle relaxant effects of the cocaine pyrolysis product, methylecgonidine.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Acetylcholine; Animals; Bronchodilator Agents; Carbachol; Chickens; Cocaine; Guinea Pigs; Histamine; Hot Temperature; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Trachea

1995
Simultaneous measurement of cocaine, cocaethylene, their metabolites, and "crack" pyrolysis products by gas chromatography-mass spectrometry.
    Clinical chemistry, 1994, Volume: 40, Issue:7 Pt 1

    Topics: Administration, Intranasal; Body Fluids; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Injections, Intravenous; Kinetics; Male; Saliva; Sensitivity and Specificity; Smoking; Substance-Related Disorders

1994
Methylecgonidine coats the crack particle.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 53, Issue:1

    Topics: Administration, Inhalation; Aerosols; Cocaine; Crack Cocaine; Hot Temperature; Particle Size

1996
Testing human hair and urine for anhydroecgonine methyl ester, a pyrolysis product of cocaine.
    Journal of analytical toxicology, 1995, Volume: 19, Issue:6

    Topics: Cocaine; Dopamine Uptake Inhibitors; Gas Chromatography-Mass Spectrometry; Hair; Humans; Illicit Drugs; Indicators and Reagents; Trimethylsilyl Compounds

1995
Generation of stable test atmospheres of cocaine base and its pyrolyzate, methylecgonidine, and demonstration of their biological activity.
    Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:2

    Topics: Administration, Inhalation; Aerosols; Animals; Atmosphere Exposure Chambers; Cocaine; Crack Cocaine; Hemodynamics; Male; Narcotics; Particle Size; Saimiri; Syringes

1996
Evidence of crack use by anhydroecgonine methylester identification.
    Human & experimental toxicology, 1997, Volume: 16, Issue:2

    Topics: Cocaine; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Narcotics; Substance Abuse Detection; Sweat

1997
Effect of cocaine and methylecgonidine on intracellular Ca2+ and myocardial contraction in cardiac myocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:2 Pt 2

    Topics: Actin Cytoskeleton; Animals; Calcium; Cell Separation; Cocaine; Ferrets; Intracellular Membranes; Myocardial Contraction; Myocardium; Narcotics; Receptors, Muscarinic

1997
Negative inotropic effect of methylecgonidine, a major product of cocaine base pyrolysis, on ferret and human myocardium.
    Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:3

    Topics: Adjuvants, Anesthesia; Anesthetics, Local; Animals; Atropine; Cocaine; Cyclic AMP; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Ferrets; Humans; Lidocaine; Male; Myocardial Contraction; Nitric Oxide Synthase; Papillary Muscles

1997
Cocaine blockade of the acetylcholine-activated muscarinic K+ channel in ferret cardiac myocytes.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:1

    Topics: Acetylcholine; Action Potentials; Animals; Cocaine; Ferrets; Heart; Male; Potassium Channel Blockers; Receptors, Muscarinic

1998
Electron ionization mass fragmentometric detection of urinary ecgonidine, a hydrolytic product of methylecgonidine, as an indicator of smoking cocaine.
    Journal of mass spectrometry : JMS, 1999, Volume: 34, Issue:6

    Topics: Cocaine; Cocaine-Related Disorders; Gas Chromatography-Mass Spectrometry; Humans; Hydrolysis; Indicators and Reagents; Substance Abuse Detection

1999
Gas chromatographic-mass spectrometric detection of anhydroecgonine methyl ester (methylecgonidine) in human serum as evidence of recent smoking of crack.
    Journal of chromatography. B, Biomedical sciences and applications, 1999, Nov-26, Volume: 735, Issue:1

    Topics: Acetamides; Artifacts; Cocaine; Crack Cocaine; Fluoroacetates; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Organosilicon Compounds; Reference Values; Sensitivity and Specificity; Smoking

1999
Quantitation of cocaine, benzoylecgonine, cocaethylene, methylecgonine, and norcocaine in human hair by positive ion chemical ionization (PICI) gas chromatography-tandem mass spectrometry.
    Journal of analytical toxicology, 2000, Volume: 24, Issue:7

    Topics: Biotransformation; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Gas Chromatography-Mass Spectrometry; Hair; Humans; Reproducibility of Results; Substance Abuse Detection

2000
Stability of methylecgonidine and ecgonidine in sheep plasma in vitro.
    Clinical chemistry, 2000, Volume: 46, Issue:11

    Topics: Animals; Biomarkers; Cocaine; Drug Stability; Gas Chromatography-Mass Spectrometry; Sheep; Substance Abuse Detection

2000
Evidence for cocaine and methylecgonidine stimulation of M(2) muscarinic receptors in cultured human embryonic lung cells.
    British journal of pharmacology, 2001, Volume: 132, Issue:2

    Topics: Blotting, Western; Carbachol; Cells, Cultured; Cocaine; Cyclic AMP; Cyclic GMP; Dopamine Uptake Inhibitors; Enzyme Induction; Humans; Lung; Muscarinic Agonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Precipitin Tests; Receptor, Muscarinic M2; Receptors, Muscarinic

2001
Examination of postmortem fluids and tissues for the presence of methylecgonidine, ecgonidine, cocaine, and benzoylecgonine using solid-phase extraction and gas chromatography-mass spectrometry.
    Clinical chemistry, 2001, Volume: 47, Issue:6

    Topics: Body Fluids; Cocaine; Gas Chromatography-Mass Spectrometry; Humans; Postmortem Changes

2001
Preliminary studies of a fast screening method for cocaine and cocaine metabolites in urine using hollow fibre membrane solvent microextraction (HFMSME).
    The Analyst, 2001, Volume: 126, Issue:8

    Topics: Adult; Chromatography, Gas; Cocaine; Half-Life; Humans; Microchemistry; Substance Abuse Detection

2001
Enhancement of nitric oxide production by methylecgonidine in cultured neonatal rat cardiomyocytes.
    British journal of pharmacology, 2002, Volume: 135, Issue:1

    Topics: Animals; Animals, Newborn; Blotting, Western; Carbachol; Cells, Cultured; Cholinergic Agonists; Cocaine; Cyclic AMP; Cyclic GMP; Enzyme Induction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Receptors, Muscarinic; Signal Transduction; Transfection

2002
Identification of anhydroecgonine methyl ester N-oxide, a new metabolite of anhydroecgonine methyl ester, using electrospray mass spectrometry.
    Journal of mass spectrometry : JMS, 2002, Volume: 37, Issue:5

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cocaine; Crack Cocaine; Heroin; Humans; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Rats; Smoking; Spectrometry, Mass, Electrospray Ionization

2002
Studies on hydrolytic and oxidative metabolic pathways of anhydroecgonine methyl ester (methylecgonidine) using microsomal preparations from rat organs.
    Chemical research in toxicology, 2002, Volume: 15, Issue:12

    Topics: Animals; Brain; Catalysis; Cocaine; Gas Chromatography-Mass Spectrometry; Hydrolysis; Isocitrate Dehydrogenase; Kidney; Lung; Male; Microsomes; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Tissue Distribution

2002
Detecting crack and other cocaine use with fastpatches.
    Addiction biology, 2003, Volume: 8, Issue:2

    Topics: Administration, Cutaneous; Adult; Cocaine; Cocaine-Related Disorders; Crack Cocaine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Substance Abuse Detection; Sweat; Time Factors

2003
Artifact production in the assay of anhydroecgonine methyl ester in serum using gas chromatography-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003, Jul-25, Volume: 792, Issue:2

    Topics: Artifacts; Calibration; Cocaine; Gas Chromatography-Mass Spectrometry; Sensitivity and Specificity

2003
Pharmacokinetics and pharmacodynamics of methylecgonidine, a crack cocaine pyrolyzate.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:3

    Topics: Animals; Atropine Derivatives; Blood Pressure; Cocaine; Crack Cocaine; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Half-Life; Heart Rate; Hemodynamics; Indicators and Reagents; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Sheep

2003
Concentration profiles of cocaine, pyrolytic methyl ecgonidine and thirteen metabolites in human blood and urine: determination by gas chromatography-mass spectrometry.
    Biomedical chromatography : BMC, 2005, Volume: 19, Issue:9

    Topics: Cocaine; Gas Chromatography-Mass Spectrometry; Humans

2005
Analysis of cocaine and three of its metabolites in hair by gas chromatography-mass spectrometry using ion-trap detection for CI/MS/MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Nov-05, Volume: 826, Issue:1-2

    Topics: Adolescent; Adult; Calibration; Cocaine; Female; Gas Chromatography-Mass Spectrometry; Hair; Humans; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity

2005
Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim.
    Journal of forensic sciences, 2005, Volume: 50, Issue:6

    Topics: Adult; Alcoholism; Central Nervous System Depressants; Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Drug Overdose; Ethanol; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry

2005
Detection of smoked cocaine marker (anhydroecgonine methylester) in nails.
    Journal of analytical toxicology, 2005, Volume: 29, Issue:7

    Topics: Adult; Biomarkers; Cocaine; Crack Cocaine; Forensic Medicine; Gas Chromatography-Mass Spectrometry; Humans; Male; Nails; Narcotics; Smoking; Substance Abuse Detection

2005
Application of discriminant analysis to differentiate between incorporation of cocaine and its congeners into hair and contamination.
    Forensic science international, 2008, Mar-21, Volume: 176, Issue:1

    Topics: Cocaine; Discriminant Analysis; Dopamine Uptake Inhibitors; Drug Contamination; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Humans; Substance Abuse Detection

2008
Development and validation of a solid-phase extraction gas chromatography-mass spectrometry method for the simultaneous quantification of methadone, heroin, cocaine and metabolites in sweat.
    Analytical and bioanalytical chemistry, 2008, Volume: 392, Issue:1-2

    Topics: Cocaine; Codeine; Gas Chromatography-Mass Spectrometry; Heroin; Humans; Methadone; Morphine Derivatives; Solid Phase Extraction; Sweat

2008
Simple method for determination of cocaine and main metabolites in urine by CE coupled to MS.
    Electrophoresis, 2009, Volume: 30, Issue:12

    Topics: Cocaine; Electrophoresis, Capillary; Humans; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity

2009
Sensitive method for detection of cocaine and associated analytes by liquid chromatography-tandem mass spectrometry in urine.
    Journal of analytical toxicology, 2009, Volume: 33, Issue:8

    Topics: Chromatography, High Pressure Liquid; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Ethanol; Gas Chromatography-Mass Spectrometry; Humans; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry

2009
In silico binary classification QSAR models based on 4D-fingerprints and MOE descriptors for prediction of hERG blockage.
    Journal of chemical information and modeling, 2010, Jul-26, Volume: 50, Issue:7

    Topics: Carbolines; Cardiotoxins; Chemistry, Pharmaceutical; Cocaine; Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Molecular Structure; Nicotine; Quantitative Structure-Activity Relationship; Software

2010
A fatally mistaken fruit juice drink: an unordinary way of cocaine intoxication.
    Journal of forensic and legal medicine, 2010, Volume: 17, Issue:8

    Topics: Adult; Beverages; Citrus sinensis; Cocaine; Commerce; Crime; Forensic Pathology; Forensic Toxicology; Humans; Internet; Liver; Male; Myocardium; Narcotics; Vitreous Body

2010
Neurotoxicity of anhydroecgonine methyl ester, a crack cocaine pyrolysis product.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 128, Issue:1

    Topics: Animals; Cells, Cultured; Cocaine; Female; Hippocampus; Immunohistochemistry; Pregnancy; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Wistar; Tritium

2012
Cocaine in sudden and unexpected death: a review of 49 post-mortem cases.
    Forensic science international, 2013, Apr-10, Volume: 227, Issue:1-3

    Topics: Adolescent; Adult; Aged; Amphetamines; Analgesics, Opioid; Australia; Benzodiazepines; Cause of Death; Central Nervous System Depressants; Cocaine; Death, Sudden; Ethanol; Fatty Liver; Female; Forensic Pathology; Forensic Toxicology; Heart Diseases; Hepatitis C; Humans; Male; Middle Aged; Narcotics; Young Adult

2013
[Passive cocaine inhalation by a 25-month-old child].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2013, Volume: 20, Issue:6

    Topics: Bacterial Infections; Child, Preschool; Cocaine; Developmental Disabilities; Diagnosis, Differential; Female; Hair; Humans; Psychomotor Disorders; Seizures, Febrile; Time Factors

2013
Development and validation of a single LC-MS/MS assay following SPE for simultaneous hair analysis of amphetamines, opiates, cocaine and metabolites.
    Forensic science international, 2014, Volume: 234

    Topics: Amphetamines; Analgesics, Opioid; Chromatography, Liquid; Cocaine; Forensic Toxicology; Hair; Humans; Limit of Detection; Male; Narcotics; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry

2014
M1 and M3 muscarinic receptors may play a role in the neurotoxicity of anhydroecgonine methyl ester, a cocaine pyrolysis product.
    Scientific reports, 2015, Dec-02, Volume: 5

    Topics: Animals; Apoptosis; CHO Cells; Cocaine; Cricetinae; Cricetulus; DNA Fragmentation; Female; Hippocampus; Neurotoxicity Syndromes; Neurotoxins; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Time Factors

2015
Anhydroecgonine Methyl Ester (AEME), a Product of Cocaine Pyrolysis, Impairs Spatial Working Memory and Induces Striatal Oxidative Stress in Rats.
    Neurotoxicity research, 2018, Volume: 34, Issue:4

    Topics: Animals; Cocaine; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Memory Disorders; Memory, Short-Term; Oxidative Stress; Prefrontal Cortex; Rats, Wistar; Spatial Memory

2018
Rapid, Secure Drug Testing Using Fingerprint Development and Paper Spray Mass Spectrometry.
    Clinical chemistry, 2017, Volume: 63, Issue:11

    Topics: Cocaine; Dermatoglyphics; Humans; Limit of Detection; Mass Spectrometry; Paper; Saliva; Substance Abuse Detection; Sweat

2017
Highly sensitive and specific on-site detection of serum cocaine by a low cost aptasensor.
    Biosensors & bioelectronics, 2018, Jun-15, Volume: 108

    Topics: Aptamers, Nucleotide; Biosensing Techniques; Buffers; Cocaine; Electrochemical Techniques; Electrodes; Endopeptidase K; Gold; Humans; Immobilized Nucleic Acids; Kinetics; Limit of Detection; Time Factors

2018
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS.
    Forensic science international, 2018, Volume: 289

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Cocaine; Crack Cocaine; Humans; Illicit Drugs; Liquid-Liquid Extraction; Mass Spectrometry; Reproducibility of Results; Substance Abuse Detection

2018
Discrimination between chewing of coca leaves or drinking of coca tea and smoking of "paco" (coca paste) by hair analysis. A preliminary study of possibilities and limitations.
    Forensic science international, 2019, Volume: 297

    Topics: Acetone; Adolescent; Adult; Biomarkers; Coca; Cocaine; Cocaine-Related Disorders; Female; Hair; Humans; Male; Mastication; Middle Aged; Plant Leaves; Pyrrolidines; Smoking; Substance Abuse Detection; Tea; Young Adult

2019
Profiling cocaine residues and pyrolytic products in wastewater by mixed-mode liquid chromatography-tandem mass spectrometry.
    Drug testing and analysis, 2019, Volume: 11, Issue:7

    Topics: Brazil; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Reverse-Phase; Cocaine; Drug Residues; Illicit Drugs; Levamisole; Pyrolysis; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2019
AEME production in cocaine positive hair after thermal hair treatment.
    Forensic science international, 2019, Volume: 302

    Topics: Biomarkers; Cocaine; Cocaine-Related Disorders; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Hair; Hair Preparations; Humans; In Vitro Techniques; Narcotics; Substance Abuse Detection

2019
Anhydroecgonine methyl ester, a cocaine pyrolysis product, contributes to cocaine-induced rat primary hippocampal neuronal death in a synergistic and time-dependent manner.
    Archives of toxicology, 2021, Volume: 95, Issue:5

    Topics: Animals; Cocaine; Gas Chromatography-Mass Spectrometry; Hippocampus; Neurons; Neurotoxicity Syndromes; Pyrolysis; Rats

2021