angiotensin ii has been researched along with wortmannin in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (9.30) | 18.2507 |
| 2000's | 36 (83.72) | 29.6817 |
| 2010's | 2 (4.65) | 24.3611 |
| 2020's | 1 (2.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Balla, T; Catt, KJ; Nakanishi, S | 1 |
| Earp, HS; Graves, LM; Li, X; Yu, H | 1 |
| Kawahara, Y; Okuda, M; Takahashi, T; Takeshita, A; Ueno, H; Yokoyama, M | 1 |
| Anand-Srivastava, MB; Ge, C | 1 |
| Baba, A; Hashimoto, H; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
| Draeger, A; Houssa, B; Ohanian, J; Ohanian, V; van Blitterswijk , WJ; Walker, AJ | 1 |
| Egan, BM; Greene, EL; Lu, G; Zhang, D | 1 |
| de Zeeuw, D; Filipeanu, CM; Henning, RH; Nelemans, A | 1 |
| Guillemot, L; Levy, A; Raymondjean, M; Rothhut, B | 1 |
| Goodchild, AK; Pilowsky, PM; Seyedabadi, M | 1 |
| Kuwahara, M | 1 |
| Balla, T; Baukal, AJ; Bor, M; Catt, KJ; Gaborik, Z; Hunyady, L; Lodge, R; Olivares-Reyes, JA; Szaszak, M | 1 |
| Griendling, KK; Rocic, P; Seshiah, PN; Taniyama, Y; Valppu, L; Weber, DS | 1 |
| Block, ER; Li, YD; Patel, JM | 1 |
| Andresen, BT; Jackson, EK; Linnoila, JJ; Romero, GG | 1 |
| Cohen, RA; Hou, X; Jiang, B; Pimentel, DR; Xu, S | 1 |
| Garnovskaya, MN; Grewal, JS; Mukhin, YV; Raymond, JR; Tholanikunnel, BG; Ullian, ME; Vlasova, TM | 1 |
| Isenovic, ER; Jamali, N; Meng, Y; Milivojevic, N; Sowers, JR | 1 |
| Barbot, C; Bondeva, T; Henaff, M; Le Blanc, C; Macrez, N; Mironneau, C; Wetzker, R | 1 |
| Chester, AH; Hafizi, S; Proud, CG; Wang, X; Yacoub, MH | 1 |
| Christoffersen, T; Dajani, O; Nilssen, LS; Sandnes, D | 1 |
| Cho, H; Ho, WK; Lee, D; Lee, SH | 1 |
| Marsigliante, S; Muscella, A; Storelli, C | 1 |
| Caruso-Neves, C; Guggino, WB; Kwon, SH | 1 |
| Anand-Srivastava, MB; Hashim, S; Li, Y | 2 |
| Alvarez, SE; Ayub, MJ; Ciuffo, GM; Villarreal, RS | 1 |
| Bell, RM; Clark, JE; Hearse, DJ; Shattock, MJ | 1 |
| Goalstone, ML; Sharma, G | 1 |
| Ahmed, RA; Cao, WM; Imachi, H; Ishida, T; Kosaka, H; Li, J; Matsumoto, K; Murao, K; Nishiuchi, T; Unterman, TG; Wong, NC; Yu, X | 1 |
| Dominici, FP; Giani, JF; Gironacci, MM; Muñoz, MC; Peña, C; Turyn, D | 1 |
| Nakamura, J | 1 |
| Bae, YS; Catt, KJ; Choi, H; Hunyady, L; Leto, TL; Rhee, SG | 1 |
| Balla, A; Balla, T; Kim, YJ; Knight, Z; Shokat, KM; Szentpetery, Z; Varnai, P | 1 |
| Albert, AP; Large, WA; Saleh, SN | 1 |
| Banach, K; Hofgaard, JP; Holstein-Rathlou, NH; Jørgensen, HK; Mollerup, S; Nielsen, MS; Olesen, SP | 1 |
| Catt, KJ; Chen, H; Li, B; Yin, X | 1 |
| González, I; Jiménez, E; Montiel, M; Pérez de la Blanca, E; Salas, J; Urso, L | 1 |
| Carraro-Lacroix, LR; Girardi, AC; Malnic, G | 1 |
| Castillo, C; Castillo, EF; López, RM; Pérez, T | 1 |
| Ciarimboli, G; Guckel, D; Pavenstädt, H; Schlatter, E | 1 |
| Miao, FA; Xu, JG; Zhang, GH; Zhang, Y | 1 |
43 other study(ies) available for angiotensin ii and wortmannin
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Inhibition of agonist-stimulated inositol 1,4,5-trisphosphate production and calcium signaling by the myosin light chain kinase inhibitor, wortmannin.
Topics: Alkaloids; Androstadienes; Angiotensin II; Animals; Azepines; Calcium; Carbazoles; Cattle; Cells, Cultured; Chromones; Cytoplasm; Epoxy Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Inositol 1,4,5-Trisphosphate; Ionomycin; Kinetics; Myosin-Light-Chain Kinase; Signal Transduction; Time Factors; Wortmannin; Zona Glomerulosa | 1994 |
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells.
Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver; Mitogen-Activated Protein Kinases; Models, Biological; Polyenes; Protein Kinases; Rats; Recombinant Proteins; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin | 1997 |
Angiotensin II stimulates mitogen-activated protein kinases and protein synthesis by a Ras-independent pathway in vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Muscle, Smooth, Vascular; Protein Biosynthesis; Protein-Tyrosine Kinases; ras Proteins; Rats; Vasoconstrictor Agents; Wortmannin | 1997 |
Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in AII-mediated enhanced expression of Gi proteins in vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dactinomycin; Embryo, Mammalian; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Transcription, Genetic; Wortmannin | 1998 |
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Bradykinin; Bucladesine; Cerebral Cortex; Chelating Agents; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Paxillin; Pertussis Toxin; Phosphoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Diacylglycerol kinase theta is translocated and phosphoinositide 3-kinase-dependently activated by noradrenaline but not angiotensin II in intact small arteries.
Topics: Androstadienes; Angiotensin II; Animals; Arteries; Arterioles; Cell Membrane; Cells, Cultured; Cytosol; Diacylglycerol Kinase; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Female; Immunohistochemistry; In Vitro Techniques; Muscle, Smooth, Vascular; Norepinephrine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Wortmannin | 2001 |
Signaling events mediating the additive effects of oleic acid and angiotensin II on vascular smooth muscle cell migration.
Topics: Acetylcysteine; Analysis of Variance; Androstadienes; Angiotensin II; Animals; Cell Movement; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Indoles; Maleimides; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oleic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Signal Transduction; Wortmannin | 2001 |
Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Cell Count; Cell Division; Dose-Response Relationship, Drug; Imidazoles; Liposomes; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Pyridines; Thymidine; Wortmannin | 2001 |
Angiotensin II-induced transcriptional activation of the cyclin D1 gene is mediated by Egr-1 in CHO-AT(1A) cells.
Topics: Androstadienes; Angiotensin II; Animals; Binding Sites; Butadienes; Cell Line; Cell Nucleus; CHO Cells; Cricetinae; Cyclin D1; DNA Mutational Analysis; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Genes, Dominant; Humans; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mutagenesis, Site-Directed; Nitriles; Phosphatidylinositol 3-Kinases; Promoter Regions, Genetic; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Transcription Factors; Transcriptional Activation; Transfection; Tyrosine; Up-Regulation; Wortmannin | 2001 |
Differential role of kinases in brain stem of hypertensive and normotensive rats.
Topics: Androstadienes; Angiotensin II; Animals; Apnea; Blood Pressure; Brain Stem; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Wortmannin | 2001 |
Involvement of Rho and tyrosine kinase in angiotensin II-induced actin reorganization in mesothelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Actins; ADP Ribose Transferases; Androstadienes; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Botulinum Toxins; Cell Line; Enzyme Inhibitors; Epithelial Cells; Genistein; Indoles; Maleimides; Microscopy, Confocal; Pertussis Toxin; Protein Kinase C; Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; rho GTP-Binding Proteins; Time Factors; Virulence Factors, Bordetella; Wortmannin | 2002 |
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor.
Topics: Androstadienes; Angiotensin II; Biomarkers; Cell Line; Cells, Cultured; Chromones; Clathrin-Coated Vesicles; Cytoplasmic Vesicles; Endocytosis; Endosomes; Humans; Morpholines; Phosphatidylinositol 3-Kinases; rab4 GTP-Binding Proteins; rab5 GTP-Binding Proteins; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Recombinant Fusion Proteins; Transferrin; Wortmannin | 2002 |
Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators.
Topics: Androstadienes; Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Hydrogen Peroxide; Indoles; Male; Maleimides; Morpholines; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyrimidines; rac GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; src-Family Kinases; Time Factors; Wortmannin | 2002 |
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Angiotensin II; Animals; Anti-Bacterial Agents; Cell Division; Cells, Cultured; Endothelium; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Swine; Wortmannin | 2002 |
Role of EGFR transactivation in angiotensin II signaling to extracellular regulated kinase in preglomerular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Enzyme Inhibitors; ErbB Receptors; Kidney Glomerulus; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth; Phospholipase D; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Wortmannin | 2003 |
Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK.
Topics: Adenoviridae; Androstadienes; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Inflammation; Interleukin-1; Isoenzymes; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Vascular Cell Adhesion Molecule-1; Wortmannin | 2004 |
Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation.
Topics: Androstadienes; Angiotensin II; Animals; Aorta; Blotting, Western; Cell Membrane; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Immunoblotting; Mitogen-Activated Protein Kinases; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Rats; Retinoblastoma Protein; Serine; Serotonin; Time Factors; Wortmannin | 2004 |
Ang II attenuates IGF-1-stimulated Na+, K(+)-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Cells, Cultured; Enzyme Inhibitors; Insulin-Like Growth Factor I; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Wortmannin | 2004 |
Regulation of vascular L-type Ca2+ channels by phosphatidylinositol 3,4,5-trisphosphate.
Topics: Androstadienes; Angiotensin II; Animals; Barium; Calcium; Calcium Channels, L-Type; Calmodulin-Binding Proteins; Cells, Cultured; Class Ib Phosphatidylinositol 3-Kinase; Cytosol; Dihydropyridines; Enzyme Inhibitors; Ion Channel Gating; Ion Transport; Isoenzymes; Lipid Metabolism; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Neurogranin; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Portal Vein; Protein Processing, Post-Translational; Rats; Rats, Wistar; Recombinant Fusion Proteins; Substrate Specificity; Transfection; Wortmannin | 2004 |
ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Angiotensin II; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Chromones; Coronary Vessels; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Humans; Immunosuppressive Agents; Morpholines; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Sustained diacylglycerol accumulation resulting from prolonged G protein-coupled receptor agonist-induced phosphoinositide breakdown in hepatocytes.
Topics: 1-Butanol; Androstadienes; Angiotensin II; Animals; Cells, Cultured; Diglycerides; Dinoprost; Enzyme Activation; Hepatocytes; Male; Norepinephrine; Oxytocics; Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipase D; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Type C Phospholipases; Vasoconstrictor Agents; Vasopressins; Wortmannin | 2005 |
Receptor-induced depletion of phosphatidylinositol 4,5-bisphosphate inhibits inwardly rectifying K+ channels in a receptor-specific manner.
Topics: Acetylcholine; Androstadienes; Angiotensin II; Animals; Bradykinin; Dinoprost; Endothelin-1; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gq-G11; In Vitro Techniques; Mice; Myocytes, Cardiac; Naphthalenes; Patch-Clamp Techniques; Phenylephrine; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Inwardly Rectifying; Wortmannin | 2005 |
Atypical PKC-zeta and PKC-iota mediate opposing effects on MCF-7 Na+/K+ATPase activity.
Topics: Androstadienes; Angiotensin II; Animals; Blotting, Western; Breast Neoplasms; Cattle; Cell Line, Tumor; Chromones; Culture Media, Serum-Free; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Kinetics; Maleimides; Morpholines; Oligodeoxyribonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Wortmannin | 2005 |
Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation.
Topics: Albumins; Androstadienes; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Fractionation; Cell Line; Chromones; Endocytosis; Imidazoles; Kidney Tubules, Proximal; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 2; Staurosporine; Sus scrofa; Wortmannin | 2005 |
Small cytoplasmic domain peptides of natriuretic peptide receptor-C attenuate cell proliferation through Gialpha protein/MAP kinase/PI3-kinase/AKT pathways.
Topics: Amino Acid Sequence; Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Cell Line; Cell Proliferation; Endothelin-1; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Receptors, Atrial Natriuretic Factor; Signal Transduction; Vasoconstrictor Agents; Wortmannin | 2006 |
Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes.
Topics: Androstadienes; Angiotensin II; Animals; Cell Membrane; Genistein; Insulin; Insulin Receptor Substrate Proteins; Liver; Male; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Tyrosine; Vasoconstrictor Agents; Wortmannin | 2006 |
Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqalpha/MAP kinase signaling pathways.
Topics: Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blotting, Western; Cell Line; Cell Proliferation; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Flavonoids; GTP-Binding Protein alpha Subunits, Gq-G11; Leucine; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Stimulation, Chemical; Wortmannin | 2006 |
Reperfusion kinase phosphorylation is essential but not sufficient in the mediation of pharmacological preconditioning: Characterisation in the bi-phasic profile of early and late protection.
Topics: Androstadienes; Angiotensin II; Animals; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oncogene Protein v-akt; Perfusion; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Time Factors; Wortmannin | 2007 |
Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Enzyme Activation; Flavonoids; Insulin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Muscle, Smooth, Vascular; Myogenic Regulatory Factors; Phosphorylation; Rats; Wortmannin | 2007 |
Regulation of scavenger receptor class BI gene expression by angiotensin II in vascular endothelial cells.
Topics: Androstadienes; Angiotensin II; Cells, Cultured; Chromones; Down-Regulation; Endothelium, Vascular; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Imidazoles; Morpholines; Nitric Oxide Synthase; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class B; Tetrazoles; Wortmannin | 2007 |
Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.
Topics: Androstadienes; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Insulin; Insulin Receptor Substrate Proteins; Janus Kinase 2; Losartan; Male; Myocardium; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Tyrphostins; Wortmannin | 2007 |
Protein kinase C-dependent antilipolysis by insulin in rat adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Androstadienes; Angiotensin II; Animals; Carbazoles; Carcinogens; Dobutamine; Enzyme Activation; Enzyme Inhibitors; Glycerol; Imidazoles; Indoles; Insulin; Isoenzymes; Lipolysis; Male; Maleimides; Protein Kinase C; Rats; Receptor, Insulin; Tetradecanoylphorbol Acetate; Wortmannin | 2007 |
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Androstadienes; Angiotensin II; Animals; Cell Line; CHO Cells; Chromones; Cricetinae; Cricetulus; Gene Expression; Humans; Indoles; Maleimides; Membrane Glycoproteins; Morpholines; Mutation; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Kinase C; Pyrazoles; Pyrimidines; Quinazolines; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tyrphostins; Wortmannin | 2008 |
Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha.
Topics: 1-Phosphatidylinositol 4-Kinase; Androstadienes; Angiotensin II; Calcium Signaling; Carrier Proteins; Cell Line; Cell Membrane; Hormones; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipase C delta; Protein Kinase Inhibitors; Protein Structure, Tertiary; Protein Transport; Recombinant Fusion Proteins; RNA Interference; Saccharomyces cerevisiae Proteins; Wortmannin | 2008 |
Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5-bisphosphate in mesenteric artery myocytes.
Topics: Androstadienes; Angiotensin II; Animals; Antibodies; Cells, Cultured; Chromones; Diglycerides; Electrophysiology; Mesenteric Arteries; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 4,5-Diphosphate; Rabbits; TRPC Cation Channels; Vasoconstrictor Agents; Wortmannin | 2008 |
Phosphatidylinositol-bisphosphate regulates intercellular coupling in cardiac myocytes.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Arachidonic Acid; Calcium; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Gap Junctions; GTP-Binding Protein alpha Subunits, Gq-G11; Myocardial Contraction; Myocytes, Cardiac; Norepinephrine; Phosphatidylinositol Phosphates; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta-1; Signal Transduction; Time Factors; Wortmannin | 2008 |
Differential signaling pathways in angiotensin II- and epidermal growth factor-stimulated hepatic C9 cells.
Topics: Androstadienes; Angiotensin II; Base Sequence; Calcium; Cell Line; Cholesterol; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epidermal Growth Factor; Filipin; Humans; Liver; Morpholines; Nystatin; Phosphorylation; RNA, Small Interfering; Signal Transduction; Wortmannin | 2008 |
Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells.
Topics: Androstadienes; Angiotensin II; Anthracenes; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Kinase 1; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Morpholines; Oligonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Umbilical Veins; Wortmannin | 2009 |
Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells.
Topics: Ammonium Chloride; Androstadienes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Buffers; Cell Line, Transformed; Cell Membrane; Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression; Genistein; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Losartan; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Protein-Tyrosine Kinases; Pyridines; Rats; Time Factors; Up-Regulation; Vacuolar Proton-Translocating ATPases; Wortmannin | 2009 |
Effects induced by inhibitors of the phosphatidylinositol 3-kinase/Akt and nitric oxide synthase/guanylyl cyclase pathways on the isometric contraction in rat aorta: a comparative study.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Chromones; Endothelium, Vascular; Guanylate Cyclase; Isometric Contraction; Male; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Phenylephrine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Potassium; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin | 2011 |
Regulation of organic cation transport in isolated mouse proximal tubules involves complex changes in protein trafficking and substrate affinity.
Topics: Androstadienes; Angiotensin II; Animals; Basement Membrane; Calmodulin; Cimetidine; Colchicine; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Fluorescent Dyes; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred C57BL; Organic Cation Transport Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein Transport; Pyridinium Compounds; Signal Transduction; Substrate Specificity; Tubulin Modulators; Wortmannin | 2012 |
Angiotensin II enhances the proliferation of Natural Killer/T-cell lymphoma cells via activating PI3K/Akt signaling pathway.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Heterocyclic Compounds, 3-Ring; Humans; Losartan; Lymph Nodes; Lymphoma, Extranodal NK-T-Cell; Male; Middle Aged; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Signal Transduction; Wortmannin; Xenograft Model Antitumor Assays | 2020 |