Page last updated: 2024-08-22

angiotensin ii and valsartan

angiotensin ii has been researched along with valsartan in 282 studies

Research

Studies (282)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	49 (17.38)	18.2507
2000's	159 (56.38)	29.6817
2010's	60 (21.28)	24.3611
2020's	14 (4.96)	2.80

Authors

Authors	Studies
Anzini, M; Cappelli, A; De Benedetti, PG; Ferrari, F; Gallelli, A; Giorgi, G; Makovec, F; Mennuni, L; Menziani, MC; Pericot Mohr Gl, Gl; Rizzo, M; Vomero, S	1
Anzini, M; Cappelli, A; Caselli, G; Ferrari, F; Gallelli, A; Giordani, A; Giorgi, G; Giuliani, G; Makovec, F; Mennuni, L; Mohr, Gl; Nannicini, C; Peris, W; Valenti, S; Vomero, S	1
Cohen, T; de Gasparo, M; Howald, H; Müller, P; Racine-Poon, A; Sioufi, A	1
Cumin, F; Kelly, M; Samani, NJ; Wood, JM	1
Lüscher, TF; Tschudi, MR	1
Argiolas, L; Marano, G	1
Levens, NR; Schnell, CR; Wood, JM	1
de Gasparo, M; Whitebread, S	1
Allegrini, P; Baum, HP; Cumin, F; de Gasparo, M; Drexler, H; Kästner, S; Laurent, D; Studer, R; Whitebread, S; Zierhut, W	1
Bodin, F; Cardoni, O; Corea, L; Fogari, R; Innocenti, P; Meilenbrock, S; Porcellati, C; Provvidenza, M; Sullivan, J	1
Angeli, P; Bodin, F; Fogari, R; Heath, R; Hereng, C; Holwerda, NJ; Oddou-Stock, P; Porcellati, C	1
Biollaz, J; Brunner, HR; Buclin, T; Csajka, C	1
Hirschhorn, W; Lloyd, P; Morgan, JM; Ortiz, M; Palmisano, M; Piraino, A; Prasad, PP; Spencer, S	1
Millar, AB; Thickett, DR	1
Hayashi, N; Inukai, T; Kometani, M; Nakao, K; Yamamoto, S	1
Hayashi, N; Kometani, M; Nakao, K; Yamamoto, S	1
Endlich, K; Steinhausen, M	1
Bindschedler, M; de Gasparo, M; Degen, P; Flesch, G; Preiswerk, G	1
Allen, TJ; Cao, Z; Cooper, ME; Hulthen, UL; Youssef, S	1
Black, HR; Graff, A; Levine, J; Mallows, S; Ruff, D; Shi, Y; Shute, D; Stoltz, R	1
de Gasparo, M; Flesch, G; Gasparini, M; Howald, H; Müller, P	1
Czendlik, CH; Howald, H; Preiswerk, G; Sioufi, A	1
de Gasparo, M; Fenoy, FJ; García-Salom, M; Madrid, MI; Tornel, J	2
Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR	1
Julius, S; Mann, J	1
Dubey, RK; Flammer, J; Lüscher, TF	1
Kullberg, BJ; Netea, MG; Peeters, AC; Thien, T; van der Meer, JW	1
Harder, S; Kenedi, P; Rietbrock, N; Schmidt, A; Thürmann, PA	1
Ivleva, AIa	1
Bünten, B; Grabensee, B; Németh, R; Plum, J	1
Benz, JR; Black, HR; Fitzsimmons, S; Graff, A; Reed, A; Shi, Y	1
Clair, MJ; de Gasparo, M; Hebbar, L; Hendrick, JW; Houck, WV; Kribbs, SB; Krombach, RS; Mukherjee, R; Rios, G; Spinale, FG; Whitebread, S	1
McInnes, GT	1
Thürmann, PA	2
Mann, JF	1
Brunner, HR; Burnier, M; Maillard, M; Mazzolai, L; Nussberger, J; Rossat, J	1
Leary, AC; Lim, PO; MacDonald, TM; McMahon, AD; Shiels, P	1
Chiang, YT; Gatlin, M; Glazer, R; Pool, JL	1
Zakirova, AN; Zakirova, NE	1
Kirk, JK	1
Balaev, VV; Drozdova, GA; Frolov, VA; Mustiatsa, VF; Rieger, P	1
Balaev, VV; Drozdova, GA; Frolov, VA; Mustiatsa, VF	1
Lippert, TH; Mueck, AO; Seeger, H	1
Cohn, JN	2
Gottdiener, JS	1
Kaplan, NM	1
Bohlender, J; Dietz, R; Haass, M; Höhnel, K; Luft, FC; Scheuermann, M; Thibault, G; Willenbrock, R	1
Belz, GG; Butzer, R; Kober, S; Mang, C; Mutschler, E	1
van Veldhuisen, DJ; Voors, AA	1
Coca, A; Giner, V	1
Califf, RM; Cohn, JN	1
Pfeffer, MA	1
Brunner, HR; Burnier, M; Centeno, C; Daven, V; Maillard, MP; Mazzolai, L; Nussberger, J	1
Cukon, S; Ennezat, PV; Hammer, A; Infeld, J; Jorde, UP; Le Jemtel, TH; Lisker, J; Sonnenblick, EH; Suryadevara, V	1
Bonarjee, VV; Dickstein, K	1
Benedict, C; Bunt, AM; Conlin, PR; Ribeiro, AB; Saito, I; Spence, JD; Williams, B	1
Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR	1
DelGrande, D; Shetty, SS	1
Breu, V; Dechend, R; Fiebeler, A; Ganten, D; Gulba, D; Haller, H; Luft, FC; Luther, T; Mackman, N; Mervaala, EM; Müller, DN; Park, JK; Schmidt, F; Schneider, W; Theuer, J	1
Laverty, R; Ledingham, JM	1
Birkenhäger, WH; de Leeuw, PW	1
Carey, RM; Siragy, HM	1
Blanc, J; Elghozi, JL; Lambert, G	1
Clair, MJ; de Gasparo, M; Hendrick, JW; King, MK; Mandel, J; McElmurray, JH; Mukherjee, R; New, RB; Sampson, AC; Spinale, FG	1
Cooper, ME; Gilbert, RE; Huang, XR; Johnson, RJ; Lai, KN; Lan, HY; Wu, LL; Yang, N; Yu, XQ	1
Califf, R; Edwards, S; Gallo, P; Henis, M; Leizorovicz, A; Maggioni, AP; McMurray, J; Neuhart, E; Pfeffer, MA; Rouleau, JL; Sellers, MA; Van De Werf, F; Velazquez, E	1
Burkhardt, R; Geiger, H; Gossmann, J; Haak, T; Harder, S; Klinkhardt, U; Lenz, T; Scheuermann, EH; Sedlmeyer, A	1
Cao, Z; Casley, D; Cooper, ME; Cox, A; Dean, R; Forbes, JM; Gilbert, RE; Kelly, DJ; Martinello, P	1
Andersen, SE; Pedersen, ST	1
Kano, H; Kohno, M; Minami, M; Mizushige, K; Nozaki, S; Ohmori, K; Yasunari, K; Yoshikawa, J	1
Sandmann, S; Unger, T; Yu, M	1
Burnier, M	1
Cheng, ZJ; Fiebeler, A; Ganten, D; Ganten, U; Lapatto, R; Luft, FC; Mervaala, EM; Müller, DN; Nurminen, K; Tikkanen, I; Vapaatalo, H	1
Bieringer, M; Breu, V; Dechend, R; Fiebeler, A; Haller, H; Luft, FC; Müller, DN; Park, JK; Schmidt, F; Shagdarsuren, E	1
Arnaboldi, L; Calvio, AM; Corsini, A; de Gasparo, M; Mussoni, L; Parolari, A; Sironi, L; Tremoli, E	1
Vidt, DG	1
Ramahi, TM	1
Hauner, H; Lee, YM; Skurk, T	1
Miller, AB; Srivastava, P	1
Benachi, A; Daikha-Dahmane, F; Gubler, MC; Laurent, N; Martinovic, J	1
Cao, H; Ke, YS; Yang, T	1
Kolina, IB; Neverov, NI; Shilov, EM; Shvetsov, MIu; Stavrovskaia, EV; Zakharova, EV	1
Alba, F; de Gasparo, M; Hermoso, F; Martínez, JM; Prieto, I; Ramírez, M; Ramírez, MJ; Vargas, F	1
Lewis, W; Stebbins, CL; Warren, JH; Wraa, CE	1
Shimoni, Y	1
Akishita, M; Chen, R; de Gasparo, M; Horiuchi, M; Iwai, M; Li, Z; Nakagami, H; Suzuki, J; Wu, L	1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA	1
Hasegawa, T; Kuno, A; Miki, T; Miura, T; Nishino, Y; Shimamoto, K; Tsuchida, A	1
Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Nussberger, J; Würzner, G	1
Daneshtalab, N; Jamali, F; Lewanczuk, RZ	1
Lippert, C; Mueck, AO; Seeger, H; Wallwiener, D	1
Bertram, D; Coote, JH	1
Rahman, AR; Rasool, AH; Rehman, A	1
Feely, J; Mahmud, A	1
Carey, RM; De Gasparo, M; El-Kersh, MA; Siragy, HM; Webb, RL	1
Corvol, P; Plouin, PF	1
Benigni, A; Donadoni, C; Fassi, A; Gagliardini, E; Lepre, MS; Remuzzi, A; Remuzzi, G; Sangalli, F	1
Andersson, OK; Elmfeldt, D; Friberg, PR; Fridman, KU; Wysocki, M	1
Ito, S; Kanmatsuse, K; Komatsu, K; Sved, AF; Tsukamoto, K	1
Anand, I; Cohn, JN; Gottlieb, SO; Latini, R; Maggioni, AP; Tognoni, G	1
Greenberg, BH	1
Inagaki, K; Iwanaga, Y; Kihara, Y; Mochly-Rosen, D; Onozawa, Y; Sarai, N; Takenaka, H	1
Fujita, T; Goto, A; Hara, C; Horita, S; Kunimi, M; Seki, G; Sugaya, T; Taniguchi, S; Uwatoko, S; Yamada, H; Zheng, Y	1
Amedeo Modesti, P; Bertolozzi, I; Boddi, M; Cecioni, I; Coppo, M; Formigli, L; Perna, AM; Polidori, G; Serneri, GG; Vanni, S; Zecchi-Orlandini, S	1
Edvinsson, L; Malmsjö, M; Pantev, E; Stenman, E; Wackenfors, A	1
Calvillo, L; De Angelis, N; Fiordaliso, F; Funicello, M; Gobbi, M; Latini, R; Masson, S; Mennini, T	1
Campbell, DJ	1
Alba, F; Banegas, I; de Gasparo, M; Hermoso, F; Prieto, I; Ramírez, M; Segarra, AB; Vargas, F	1
Hiratsuka, M; Ito, S; Kanmatsuse, K; Komatsu, K; Sved, AF; Tsukamoto, K	1
Komajda, M	1
Boonstra, PW; Buikema, H; Lübeck, RH; van Buiten, A; van Gilst, WH; van Veldhuisen, DJ; Voors, AA; Wagenaar, LJ	1
Ke, YS; Tao, YY; Yang, H; Yu, GH	1
Alhenc-Gelas, F; Chollet, C; Doucet, A; Helou, CM; Imbert-Teboul, M; Marchetti, J; Rajerison, R	1
Ito, S; Kanmatsuse, K; Katsunuma, N; Tsukamoto, K	1
Düsing, R; Gohlke, P; Lottermoser, K; Unger, T; Vetter, H	1
Bessard, G; Caron, F; Cracowski, JL; Hakim, A; Hoffmann, P; Sessa, C; Stanke-Labesque, F	1
Wilensky, RL	1
Abe, Y; Fukui, T; Hitomi, H; Kimura, S; Kiyomoto, H; Kobori, H; Kohno, M; Nishiyama, A; Rahman, M; Shokoji, T; Yao, L; Zhang, GX	1
Barki-Harrington, L; Luttrell, LM; Rockman, HA	1
Dominiak, P; Häuser, W	1
Arregui, B; Fenoy, FJ; López, B; Salom, MG; Valero, F	1
Bayraktutan, U	1
Bayraktutan, U; Ulker, S	1
Düsing, R; Lottermoser, K; Ulrich-Merzenich, G; Vetter, H	1
Imanishi, S; Kurata, Y; Matsuda, H; Sato, R; Shibamoto, T	1
Fujita, T; Goto, A; Hirata, Y; Nagai, R; Nishimatsu, H; Oba, S; Omata, M; Satonaka, H; Suzuki, E; Takeda, R	1
Bedigian, MP; Lu, L; Robinson, AD; Sun, Y; Weber, KT; Zhang, J	1
Doi, M; Kobayashi, S; Kohno, M; Matsuzaki, M; Oda, T; Ohkusa, T; Okuda, S; Tokuhisa, T; Yamamoto, T; Yano, M	1
Düsing, R	1
Düsing, R; Gohlke, P; Hertfelder, HJ; Lottermoser, K; Vetter, H	1
Azizi, M; Bissery, A; Lamarre-Cliche, M; Ménard, J	1
Anzai, T; Hashimoto, K; Himeno, H; Imai, K; Kawana, M; Kitakaze, M; Koretsune, Y; Maruyama, S; Masaoka, Y; Matsubara, H; Matsuoka, T; Miyao, Y; Miyatake, K; Miyauchi, T; Nakamura, Y; Nomura, F; Okamoto, H; Ozono, K; Sekiya, M; Shinohara, H; Shintani, U; Shiraki, T; Takaoka, H; Tsutamoto, T; Yasumura, Y; Yokoya, K; Yokoyama, H	1
Isaka, N; Ito, M; Kaibuchi, K; Kongo, M; Kureishi, Y; Moriki, N; Nakakuki, T; Nakano, T; Okamoto, R; Seko, T	1
Bandinelli, M; Boddi, M; Cecioni, I; Chiavarelli, M; Coppo, M; Lisi, GF; Modesti, PA; Neri Serneri, GG; Papa, ML; Toscano, T	1
Li, Q; Liu, L; Xiao, J; Xu, Z; Zhao, S	1
Angeli, F; Verdecchia, P	1
Luft, FC	1
Awad, AS; Carey, RM; Siragy, HM; Webb, RL	2
Chen, R; Hata, R; Horiuchi, M; Ide, A; Iwai, M; Liu, HW; Okamoto, S; Sakanaka, M; Shiuchi, T	1
Bahtyiar, G; Blendea, MC; Ferrario, CM; Jacobs, D; Kumar, P; McFarlane, SI; Ogrin, C; Sha, Q; Sowers, JR; Stas, S; Stump, CS	1
Abadir, P; Carey, RM; Siragy, HM; Xue, C	1
Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL	1
Azizi, M; Bissery, A; Bura-Rivière, A; Camisasca, RP; Guyenne, TT; Ménard, J; Vaidyanathan, S	1
He, Y; Savoia, C; Touyz, RM; Yao, G	1
Xie, XW; Zhao, P	1
Chen, JZ; Wang, XX; Yuan, H	1
Colson, P; Foëx, P; Guillon, G; Ryckwaert, F	1
Inoguchi, T; Kobayashi, K; Maeda, Y; Nakayama, M; Nawata, H; Sasaki, S; Sawada, F; Sonoda, N; Sonta, T; Sumimoto, H; Tsubouchi, H	1
Devine, AB; Dixon, LJ; El-Sherbeeny, NA; Hughes, SM; Leahey, WJ; McVeigh, GE; Plumb, RD	1
Chen, R; Horiuchi, M; Ide, A; Iwai, M; Li, Z; Min, LJ; Mogi, M; Okumura, M; Shiuchi, T; Suzuki, J; Tsuda, M	1
Chappell, MC; Ferrario, CM; Gallagher, PE; Tallant, EA	1
Arbolishvili, GN; Baklanova, NA; Belenkov, IuN; Mareev, VIu; Nasonova, SN; Skvortsov, AA; Sychev, AV	1
Huang, ZY; Li, S; Liu, Z; Zhu, JH	1
Braszko, JJ	1
Akutsu, H; Iwa, Y; Kizawa, H; Kondoh, R; Nagane, Y; Terayama, Y; Tohgi, H; Utsugisawa, K	1
Mitchell, A; Philipp, T; Rushentsova, U; Siffert, W; Wenzel, RR	1
Hirata, Y; Hirono, Y; Sugiyama, T; Tateno, T; Tsuchiya, K; Yoshimoto, T	1
Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Tsukuda, K	1
Baker, KM; Kumar, R	1
Baklanova, NA; Belenkov, IuN; Mareev, VIu; Masenko, VP; Nasonova, SN; Orlova, IaA; Skvortsov, AA; Sychev, AV	1
Akasaka, T; Imanishi, T; Kobayashi, K	1
Khan, F; Kumagai, N; Mahmood, J; Morioka, T; Oite, T; Okada, S	1
Akasaka, T; Goto, M; Imanishi, T; Kobayashi, K; Kuroi, A; Mochizuki, S; Yoshida, K	1
Dzau, VJ; Matsushita, K; Okamoto, Y; Pratt, RE; Wu, Y	1
Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Nahmias, C; Tomochika, H; Tsukuda, K	1
Zoccali, C	1
Bae, KS; Cho, JY; Chung, JY; Hong, KS; Jang, IJ; Lee, KH; Lim, HS; Oh, DS; Shin, SG; Yu, KS	1
Savoia, C; Schiffrin, EL; Touyz, RM; Volpe, M	1
Luan, B; Song, L	1
Cai, Y; Chen, FP; Gong, LK; Li, XH; Liu, LL; Qi, XM; Ren, J; Wang, H; Wu, XF; Xiao, Y; Zhang, L	1
Gaskin, FS; Kamada, K; Korthuis, RJ; Yusof, M	1
Chen, S; Huang, H; Li, R; Liu, P; Tang, F; Wang, P; Zhang, H	1
Cooper, SA; Ferrario, C; Govindarajan, G; Habibi, J; Hayden, MR; Karuparthi, PR; Link, D; Ma, L; Qazi, M; Sowers, JR; Stump, C; Wei, Y; Whaley-Connell, A	1
Azuma, J; Dosaka, N; Iekushi, K; Katsuragi, N; Koibuchi, N; Morishita, R; Nagao, K; Ogihara, T; Sanada, F; Taniyama, Y	1
Jones, MR; Laragh, JH; Sealey, JE	1
Murakami, M; Nakagiri, A; Sunamoto, M	1
Fujita, T; Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K	1
Azuma, K; Hashimoto, T; Ishigami, T; Lopez-Ilasaca, M; Masuda, S; Matsuda, M; Sakai, M; Shigenaga, A; Tamura, K; Tanaka, Y; Tsurumi-Ikeya, Y; Umemura, S; Wakui, H	1
Han, Q; Lei, J; Liao, YD; Wang, ZH; Xu, H; Zhang, YY	1
Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Shintaku, H; Tokutomi, Y; Yamamoto, E; Yamashita, T	1
Bissessor, N; White, H	1
Victor, RG	1
Lin, CS; Pan, CH; Wen, CH	1
Akizuki, O; Inayoshi, A; Kitayama, T; Kusaka, H; Matsubara, M; Sasaki, K; Shirakura, S; Yao, K	1
Jin, D; Kimura, M; Kirimura, K; Miyazaki, M; Sakonjo, H; Takai, S; Tanaka, K	1
Liu, Y; Meng, QH; Wang, L; Zhu, S	1
Clark, SE; Ferrario, CM; Ibdah, JA; Morris, EM; Sowers, JR; Thyfault, JP; Uptergrove, GM; Wei, Y; Whaley-Connell, AT	1
Imamura, Y; Ishida, S; Kurihara, T; Nagai, N; Noda, K; Oike, Y; Okano, H; Ozawa, Y; Shinoda, K; Tsubota, K	1
He, XX; Liang, QS; Zhan, CY; Zhou, DX	1
Koide, N; Miyashita, Y; Murano, T; Saiki, A; Shirai, K; Watanabe, F	1
Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E	1
Hashimoto, K; Horino, T; Inoue, K; Iwasaki, Y; Kagawa, T; Matsumoto, R; Morita, T; Taguchi, T; Takao, T; Terada, Y	1
Abadir, PM; Abdel-Rahman, EM; Siragy, HM	1
Lu, J; Sun, L; Yu, XJ; Zang, WJ; Zhang, CH	1
Aoki, M; Fujiwara, Y; Makino, H; Miyake, T; Morishita, R; Nishimura, M; Shiraya, S; Yamakawa, S	1
Haider, DG; Jungbauer, A; Kapiotis, S; Mueller, M; Storka, A; Vojtassakova, E; Wolzt, M	1
Furuno, M; Higaki, J; Horiuchi, M; Inaba, S; Iwai, M; Kanno, H; Mogi, M; Okayama, H; Senba, I; Tomono, Y	1
Aoyama, I; Bomsztyk, K; Komers, R; Koopmeiners, JS; Naito, M; Schnaper, HW; Shenoy, A	1
Clark, SE; Ferrario, CM; Ibdah, JA; Li, W; Sowers, JR; Thyfault, JP; Uptergrove, GM; Wei, Y; Whaley-Connell, AT	1
Akiyoshi, Y; Miyamoto, S; Morishima, M; Ono, K; Wang, Y	1
Dong, YF; Fukuda, M; Kaneko, T; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakagata, N; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Yamamoto, E	1
Ikeda, H; Jin, D; Miyazaki, M; Sakonjo, H; Takai, S	1
Wang, Q; Wu, G; Zhao, W	1
Huang, J; Siragy, HM	1
Biala, A; Eriksson, O; Finckenberg, P; Kaheinen, P; Lapatto, R; Lempiäinen, J; Louhelainen, M; Luft, FC; Martonen, E; Mattila, I; Merasto, S; Mervaala, E; Muller, DN; Oresic, M	1
Chen, X; Chen, ZG; Cheng, B; Gu, YF; Liu, HW; Liu, WZ; Wu, HJ	1
Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J	1
Biggi, A; Cabassi, A; De Iaco, G; Iori, M; Magnani, G; Montanari, A; Musiari, L; Novarini, A; Pelà, GM; Pelloni, I; Pinelli, S	1
Lin, S; Peng, W; Tang, R; Veeraragoo, P; Wu, R; Zhou, Q	1
Carretero, OA; Liao, TD; Liu, TS; Peng, H; Reudelhuber, TL; Shesely, EG; Xu, J; Yang, JJ; Yang, XP	1
Cooley, C; Kalra, A; Palaniswamy, C; Zanotti-Cavazzoni, SL	1
Bengel, FM; Bravo, PE; Dannals, RF; Fukushima, K; Higuchi, T; Javadi, MS; Lautamäki, R; Mathews, WB; Szabo, Z; Xia, J	1
Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T	1
Guan, QG; Pang, XF; Sun, DM; Xie, LN; Zeng, DY; Zhang, HS	1
Horiuchi, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Ohshima, K; Sakata, A; Tsukuda, K	1
Chen, ZY; Huang, Y; Lau, CW; Leung, FP; Tian, XY; Wong, WT; Yao, X; Yung, LH; Yung, LM	1
Hirooka, Y; Hoka, S; Ito, K; Kishi, T; Nakagaki, T; Sunagawa, K	1
Gong, J; Guo, X; Liao, H; Zhang, W	1
Chen, HY; Chen, LF; Fang, Q; Wang, W; Xu, Z; Yan, XW	1
Aono, J; Higaki, J; Horiuchi, M; Inoue, K; Iwai, M; Nagai, T; Nishimura, K; Ogimoto, A; Okayama, H; Suzuki, J	1
Durik, M; Roks, AJ; Sevá Pessôa, B	1
Fan, YY; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Mori, H; Nakano, D; Nishiyama, A	1
Benge, CD; Muldowney, JA	1
Ahmad, S; Brosnihan, KB; Ferrario, CM; Gomez, RA; Groban, L; Kato, J; Kitamura, K; Lopez, ML; Moniwa, N; Nagata, S; Simington, SW; Varagic, J; VonCannon, JL; Wang, H	1
Cheng, J; Li, C; Li, PY; Mao, L; Wen, J; Yang, Y; Yue, XL	1
Chiga, M; Iwamoto, T; Kita, S; Lin, SH; Mori, T; Oi, K; Rai, T; Sasaki, S; Sohara, E; Susa, K; Takahashi, D; Uchida, S; Yang, SS; Zeniya, M	1
Baker, KM; Chandel, N; Kumar, R; Seqqat, R; Thomas, CM; Yong, QC	1
Chen, MY; Cheng, KS; Hong, YH; Hsieh, WY; Ko, L; Kuan, TC; Liao, YC; Lin, CS; Wu, CL; Yen, CY	1
Chen, H; Hu, X; Jiang, Z; Li, J; Liu, X; Steinhoff, G; Wang, L; Xu, Y; Yu, H; Zhang, Z	1
Born, J; Derad, I; Lehnert, H; Marshall, L; Nitschke, M; Sayk, F	1
Bruder-Nascimento, T; Callera, GE; Cau, SB; Chinnasamy, P; Riascos-Bernal, DF; Sibinga, NE; Tostes, RC; Touyz, RM	1
Chen, Q; Fang, Y; Li, S; Lv, S; Tian, X; Zhou, H	1
Bai, X; Chen, X; Jin, B; Li, X; Shan, H; Yu, K; Zhang, S; Zhao, X	1
Hasan, AU; Hashimoto, T; Ishihara, N; Ishihara, Y; Kamitori, K; Kohno, M; Noma, T; Ohmori, K; Tokuda, M; Yamaguchi, F	1
Chen, G; He, QY; Pan, SF; Pan, SQ; Shen, C; Zhang, XM	1
Dong, W; Gong, G; Lin, X; Wang, X; Yang, B; Yang, Y; Yuan, B	1
Bell, PD; Bissler, JJ; Bunni, M; Dillon, J; Dixon, BP; Hellmann, AR; Ramkumar, T; Reichert, RJ; Sampson, JR; Siroky, BJ; Tsuchihashi, Z; Yin, H	1
Guo, T; Hao, P; Kong, J; Li, D; Meng, X; Yang, J; Zhang, C; Zhang, K; Zhang, M; Zhang, Y	1
Dimitriadis, F; Higashi, Y; Nakamura, K; Nemoto, T; Saito, M; Shimizu, S; Shimizu, T; Taniuchi, K; Ueba, T; Yanagita, T; Yawata, T	1
Flavahan, NA; Flavahan, S; Leung, SW; Vanhoutte, PM; Xu, A; Zhao, Y	1
Chang, JP; Chang, TH; Chen, MC; Ho, WC; Hsiao, CC; Hsu, SD; Huang, HD; Liu, WH; Wang, FS	1
Jo, CH; Simoni, J; Wesson, DE	1
Bathgate-Siryk, A; Dabul, S; Jafferjee, M; Koch, WJ; Lymperopoulos, A; McDonald, P; Sturchler, E; Valero, TR	1
Chai, M; Dong, Z; Ji, Q; Lin, Y; Liu, Y; Lu, Q; Meng, K; Wu, B; Yu, K; Zeng, Q; Zhang, J; Zhou, Y	1
Chen, J; Hu, YJ; Peng, DF; Tang, SY	1
Sui, X; Wang, D; Wei, H	1
Bai, HY; Chisaka, T; Higaki, A; Horiuchi, M; Iwanami, J; Kan-No, H; Kukida, M; Mogi, M; Nakaoka, H; Shan, BS; Tsukuda, K; Wang, XL; Yamauchi, T	1
Cheng, WP; Shyu, KG; Wang, BW	1
Chen, Z; Hu, W; Li, Y; Shen, Y; Xie, C	1
Fan, F; Li, S; Nie, W; Yan, H; Zhu, J; Zhu, W	1
Chen, S; Levi, M; Li, C; Lin, Y; Luo, R; Wang, F; Wang, W; Yang, T; Zheng, P	1
Lei, S; Lyu, C; Shao, Y; Wang, Q; Wu, C; Yuan, Q	1
Chen, X; Deng, Y; Ding, D; Hu, X; Liao, Y; Pan, Y; Qiu, Z; Song, X; Wang, M; Wang, S; Wu, H; Yang, S; Zhang, H; Zhou, Y; Zhou, Z	1
Adi-Bessalem, S; Laraba-Djebari, F; Sifi, A	1
Chen, X; Gao, X; Lu, G; Luo, C; Luo, J; Peng, L; Zuo, Z	1
Gao, J; Goodchild, TT; Kapusta, DR; Lefer, DJ; Li, Z; Polhemus, DJ; Scarborough, AL; Smart, FW; Trivedi, RK; Varner, KJ; Xia, H	1
Dalman, RL; Iida, Y; Miyata, M; Xu, B; Xuan, H	1
Gu, X; Li, Y; Wang, S; Yao, Y; Yu, B; Zhang, Q; Zhang, X; Zhang, Y	1
Agelis, G; Androutsou, ME; Antonopoulos, M; Apostolopoulos, V; Matsoukas, J; Michalatou, M; Mikkelsen, K; Qaradakhi, T; Vlahakos, DV; Zulli, A	1
Chen, XM; Huang, MJ; Li, P; Su, TY; Wang, Y; Wei, RB; Yang, Y	1
Gao, X; He, L; Sun, YH; Tian, HP; Xu, DL; Yi, YF	1
Danhof, M; Giraudel, J; Mochel, JP; Peyrou, M; Rigel, DF; Teng, CH	1
Abdo, M; Hassan, WA; Makary, S; Tawfik, MK	1
Fan, GC; Li, H; Liang, L; Peng, T; Qu, L; Yuan, W; Zhang, L	1
Deng, CY; Guo, HM; Li, X; Liu, FZ; Liu, Y; Rao, F; Wang, ZY; Wei, W; Wu, SL; Xue, YM; Yang, H; Zhang, MZ	1
Cai, SY; Fu, YL; Lin, Q; Peng, FH; Tao, L; Wang, Q; Zheng, NZ	1
Barbato, E; Bellis, A; Di Gioia, G; Mauro, C; Morisco, C; Sorriento, D; Trimarco, B	1
Huang, J; Niu, G; Wang, F; Yang, J; Zhou, M; Zhu, Z	1
Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Melton, L; Mirabito Colafella, KM; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I	1
Gu, R; Hu, X; Lenahan, C; Li, B; Li, S; Liu, J; Qu, H; Si, W; Tian, T; Wang, L; Wang, Q; Zuo, G	1
Elena Hernandez-Campos, M; Flores-Monroy, J; Lezama-Martinez, D; Martinez-Aguilar, L; Valencia-Hernandez, I	1
Li, CY; Li, SN; Xi, H; Zhang, JR; Zhao, L; Zhou, L	1
Keshawy, MM; Makary, S; Tawfik, MK	1
Alfadda, AA; Alsalman, N; Bazighifan, A; Gul, R	1
Li, D; Liu, Q; Xie, Y; Yan, J	1
Cai, Z; Fang, L; He, B; Huo, H; Jiang, Y; Liang, F; Liang, M; Pan, C; Shen, L; Shen, Y; Wang, J; Wang, Z	1
Clahsen-van Groningen, MC; Cruz-López, EO; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Kasper, A; Nioi, P; Poglitsch, M; Ren, L; Rooney, T; Uijl, E; van Veghel, R; Zlatev, I	1
Cho, N; Fukasawa, K; Ikeda, H; Kagiyama, K; Kamimura, H; Maeda, S; Matsumoto, S; Miyata, A; Suemizu, H; Uehara, S	1

Reviews

30 review(s) available for angiotensin ii and valsartan

Article	Year
Pharmacokinetic-pharmacodynamic profile of angiotensin II receptor antagonists. Clinical pharmacokinetics, 1997, Volume: 32, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Humans; Imidazoles; Losartan; Renin; Tetrazoles; Valine; Valsartan	1997
[New prospects in the treatment of arterial hypertension. Antagonist of angiotensin II valsartan (diovan)]. Terapevticheskii arkhiv, 1998, Volume: 70, Issue:9 Topics: Angiotensin II; Antihypertensive Agents; Humans; Hypertension; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan	1998
Angiotensin II antagonism in clinical practice: experience with valsartan. Journal of cardiovascular pharmacology, 1999, Volume: 33 Suppl 1 Topics: Age Factors; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Drug Synergism; Humans; Kidney Diseases; Racial Groups; Sex Factors; Tetrazoles; Valine; Valsartan	1999
Valsartan and the kidney: present and future. Journal of cardiovascular pharmacology, 1999, Volume: 33 Suppl 1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Humans; Hypertension; Kidney Diseases; Renal Insufficiency; Tetrazoles; Valine; Valsartan	1999
Angiotensin-II receptor antagonists: their place in therapy. American family physician, 1999, Volume: 59, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan	1999
Angiotensin II receptor antagonists in the treatment of hypertension. American family physician, 1999, Sep-15, Volume: 60, Issue:4 Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan	1999
[Antihypertensive advantages of angiotensin II AT1 receptor antagonism]. Revista espanola de cardiologia, 1999, Volume: 52 Suppl 3 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Heart Diseases; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	1999
Cardiac protection: evolving role of angiotensin receptor blockers. American heart journal, 2000, Volume: 139, Issue:1 Pt 2 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Therapy, Combination; Heart Failure; Hemodynamics; Humans; Middle Aged; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2000
Enhancing cardiac protection after myocardial infarction: rationale for newer clinical trials of angiotensin receptor blockers. American heart journal, 2000, Volume: 139, Issue:1 Pt 2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Myocardial Infarction; Prognosis; Receptors, Angiotensin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Valine; Valsartan; Ventricular Function, Left	2000
[Use of angiotensin II receptor blockaders in heart failure]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Mar-10, Volume: 120, Issue:7 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Heart Failure; Humans; Irbesartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2000
Angiotensin II antagonists for hypertension: are there differences in efficacy? American journal of hypertension, 2000, Volume: 13, Issue:4 Pt 1 Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2000
[Use of angiotensin-II-antagonists in hypertension]. Nederlands tijdschrift voor geneeskunde, 2000, Jul-15, Volume: 144, Issue:29 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Hypertension; Losartan; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2000
Prospective trials of angiotensin receptor blockers: beyond blood pressure control. Current hypertension reports, 2000, Volume: 2, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Hypertension; Losartan; Myocardial Infarction; Tetrazoles; Valine; Valsartan	2000
Angiotensin II type 1 receptor blockers. Circulation, 2001, Feb-13, Volume: 103, Issue:6 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Drug Design; Humans; Irbesartan; Losartan; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles; Valine; Valsartan	2001
Valsartan: a novel angiotensin type 1 receptor antagonist. Expert opinion on pharmacotherapy, 2000, Volume: 1, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications. Postgraduate medicine, 2001, Volume: 109, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan	2001
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. Cardiology clinics, 2001, Volume: 19, Issue:2 Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart Failure; Humans; Hypertension; Losartan; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan	2001
[Angiotensin II receptor blockers: current status and future prospects]. Drugs, 2002, Volume: 62 Spec No 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Drug Therapy, Combination; Heart Diseases; Humans; Hypertension; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2002
Renin-angiotensin system inhibition: how much is too much of a good thing? Internal medicine journal, 2002, Volume: 32, Issue:12 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Therapy, Combination; Humans; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2002
Angiotensin-receptor blockers: revival of the systemic prevention of restenosis? Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:1 Topics: Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Clinical Trials as Topic; Coronary Restenosis; Humans; Receptors, Angiotensin; Stents; Tetrazoles; Valine; Valsartan	2003
Assessment of the optimal daily dose of valsartan in patients with hypertension, heart failure, or both. Clinical therapeutics, 2004, Volume: 26, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Heart Failure; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2004
Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism? Kidney international, 2006, Volume: 70, Issue:12 Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Biomarkers; Calcium; Calcium Channel Blockers; Humans; Kidney Failure, Chronic; Risk Factors; Tetrazoles; Valine; Valsartan	2006
Rationale for angiotensin II receptor blocker therapy in chronic heart failure. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:2 Suppl Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Chronic Disease; Heart Failure; Humans; Long-Term Care; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2000
Valsartan in the treatment of heart failure or left ventricular dysfunction after myocardial infarction. Vascular health and risk management, 2007, Volume: 3, Issue:4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Drug Therapy, Combination; Heart Failure; Humans; Myocardial Infarction; Renin-Angiotensin System; Tetrazoles; Treatment Outcome; Valine; Valsartan; Ventricular Dysfunction, Left	2007
Pathophysiology of target-organ disease: does angiotensin II remain the key? Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:11 Suppl 4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Disease Progression; Humans; Hypertension; Losartan; Myocardial Infarction; Renin; Renin-Angiotensin System; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan	2007
Valsartan-induced angioedema in a patient on angiotensin-converting enzyme inhibitor for years: case report and literature review. American journal of therapeutics, 2012, Volume: 19, Issue:6 Topics: Aged, 80 and over; Angioedema; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hypertension; Tetrazoles; Time Factors; Valine; Valsartan	2012
The renin-angiotensin system, bone marrow and progenitor cells. Clinical science (London, England : 1979), 2012, Aug-01, Volume: 123, Issue:4 Topics: Adipogenesis; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone Marrow; Erythropoiesis; Hematopoiesis; Humans; Kidney; Mesenchymal Stem Cells; Metabolic Syndrome; Myocytes, Cardiac; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stem Cells; Tetrazoles; Valine; Valsartan	2012
The pharmacokinetics and pharmacodynamics of valsartan in the post-myocardial infarction population. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan	2012
Pathogenic and Therapeutic Significance of Angiotensin II Type I Receptor in Abdominal Aortic Aneurysms. Current drug targets, 2018, Volume: 19, Issue:11 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Aneurysm, Abdominal; Aortic Rupture; Clinical Trials as Topic; Disease Models, Animal; Disease Progression; Humans; Receptor, Angiotensin, Type 1; Telmisartan; Valsartan	2018
The Rationale of Neprilysin Inhibition in Prevention of Myocardial Ischemia-Reperfusion Injury during ST-Elevation Myocardial Infarction. Cells, 2020, 09-21, Volume: 9, Issue:9 Topics: Adrenomedullin; Aminobutyrates; Angiotensin II; Animals; Apelin; Atrial Natriuretic Factor; Biphenyl Compounds; Bradykinin; Cardiotonic Agents; Drug Combinations; Gene Expression Regulation; Humans; Mice; Myocardial Reperfusion Injury; Neprilysin; ST Elevation Myocardial Infarction; Substance P; Survival Analysis; Tetrazoles; Valsartan; Ventricular Remodeling	2020

Trials

44 trial(s) available for angiotensin ii and valsartan

Article	Year
Angiotensin II receptor blockade with single doses of valsartan in healthy, normotensive subjects. European journal of clinical pharmacology, 1994, Volume: 47, Issue:3 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Heart Rate; Humans; Male; Placebos; Renin; Reproducibility of Results; Systole; Tetrazoles; Valine; Valsartan	1994
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3 Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan	1996
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy and safety compared with placebo and enalapril. Journal of hypertension, 1996, Volume: 14, Issue:9 Topics: Adult; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan	1996
The effect of valsartan on the angiotensin II pressor response in healthy normotensive male subjects. Clinical pharmacology and therapeutics, 1997, Volume: 61, Issue:1 Topics: Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Humans; Linear Models; Male; Receptors, Angiotensin; Reference Values; Tetrazoles; Time Factors; Valine; Valsartan	1997
Pharmacokinetic and pharmacodynamic interaction of single oral doses of valsartan and furosemide. European journal of clinical pharmacology, 1997, Volume: 52, Issue:5 Topics: Administration, Oral; Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Blood Pressure; Cross-Over Studies; Diuretics; Drug Synergism; Furosemide; Humans; Male; Middle Aged; Renin; Tetrazoles; Valine; Valsartan	1997
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: efficacy, tolerability and safety compared to an angiotensin-converting enzyme inhibitor, lisinopril. Journal of human hypertension, 1997, Volume: 11, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Lisinopril; Male; Middle Aged; Safety; Tetrazoles; Treatment Outcome; Valine; Valsartan	1997
Pharmacokinetics and pharmacodynamic effects of the angiotensin II antagonist valsartan at steady state in healthy, normotensive subjects. European journal of clinical pharmacology, 1997, Volume: 52, Issue:6 Topics: Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Blood Pressure; Cross-Over Studies; Double-Blind Method; Half-Life; Heart Rate; Humans; Male; Metabolic Clearance Rate; Middle Aged; Tetrazoles; Valine; Valsartan	1997
Pharmacokinetic and pharmacodynamic interaction of single doses of valsartan and atenolol. European journal of clinical pharmacology, 1997, Volume: 52, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Atenolol; Blood Pressure; Cross-Over Studies; Drug Interactions; Exercise; Half-Life; Heart Rate; Humans; Male; Metabolic Clearance Rate; Renin; Tetrazoles; Valine; Valsartan	1997
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design. Blood pressure, 1998, Volume: 7, Issue:3 Topics: Aged; Amlodipine; Angiotensin II; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan	1998
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension. Circulation, 1998, Nov-10, Volume: 98, Issue:19 Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Echocardiography; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Tetrazoles; Treatment Outcome; Valine; Valsartan	1998
Effects of the angiotensin II antagonist valsartan on blood pressure, proteinuria, and renal hemodynamics in patients with chronic renal failure and hypertension. Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:12 Topics: Aged; Albuminuria; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Creatinine; Dextrans; Double-Blind Method; Erythrocyte Count; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Inulin; Kidney Failure, Chronic; Kidney Glomerulus; Male; Middle Aged; Molecular Weight; p-Aminohippuric Acid; Particle Size; Potassium; Prospective Studies; Proteinuria; Renal Circulation; Tetrazoles; Valine; Valsartan	1998
Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with monotherapy. Journal of human hypertension, 1998, Volume: 12, Issue:12 Topics: Adult; Angiotensin II; Antihypertensive Agents; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Headache; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan	1998
Angiotensin II antagonism and the heart: valsartan in left ventricular hypertrophy. Journal of cardiovascular pharmacology, 1999, Volume: 33 Suppl 1 Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertrophy, Left Ventricular; Male; Middle Aged; Tetrazoles; Valine; Valsartan	1999
Angiotensin II receptor blockade in normotensive subjects: A direct comparison of three AT1 receptor antagonists. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:3 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Irbesartan; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Valine; Valsartan	1999
Angiotensin II receptor subtype I antagonism and diastolic cardiac filling in man. British journal of clinical pharmacology, 1999, Volume: 47, Issue:3 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Cardiovascular Agents; Cross-Over Studies; Diastole; Double-Blind Method; Echocardiography; Heart Failure; Hemodynamics; Humans; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	1999
Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. Journal of human hypertension, 1999, Volume: 13, Issue:4 Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Posture; Renin; Tetrazoles; Treatment Outcome; Valine; Valsartan	1999
[Diovan efficacy and tolerance in mild and moderate hypertension]. Terapevticheskii arkhiv, 1999, Volume: 71, Issue:4 Topics: Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Safety; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan	1999
Influence of the angiotensin II antagonist valsartan on left ventricular hypertrophy in patients with essential hypertension. Circulation, 1999, Aug-10, Volume: 100, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Diuretics; Drug Interactions; Heart Ventricles; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Organ Size; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Research Design; Tetrazoles; Valine; Valsartan	1999
Time course and extent of angiotensin II antagonism after irbesartan, losartan, and valsartan in humans assessed by angiotensin II dose response and radioligand receptor assay. Clinical pharmacology and therapeutics, 1999, Volume: 66, Issue:4 Topics: Adult; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Losartan; Male; Radioligand Assay; Reference Values; Tetrazoles; Time Factors; Valine; Valsartan	1999
Assessment of angiotensin II receptor blockade in humans using a standardized angiotensin II receptor-binding assay. American journal of hypertension, 1999, Volume: 12, Issue:12 Pt 1-2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	1999
Effect of angiotensin II infusion with and without angiotensin II type 1 receptor blockade on nitric oxide metabolism and endothelin in human beings: a placebo-controlled study in healthy volunteers. Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:5 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Endothelins; Humans; Infusions, Intravenous; Male; Nitric Oxide; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	2000
Central and peripheral effects of angiotensin II on the cardiovascular response to exercise. Journal of cardiovascular pharmacology, 2001, Volume: 38, Issue:5 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Blood Pressure; Enalapril; Epinephrine; Exercise; Female; Heart Rate; Humans; Male; Norepinephrine; Receptor, Angiotensin, Type 1; Stroke Volume; Tetrazoles; Valine; Valsartan; Vascular Resistance	2001
Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing. Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:1 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2002
Effect of angiotensin II on pulse wave velocity in humans is mediated through angiotensin II type 1 (AT(1)) receptors. Journal of human hypertension, 2002, Volume: 16, Issue:4 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Flow Velocity; Carotid Arteries; Cross-Over Studies; Double-Blind Method; Femoral Artery; Hemodynamics; Humans; Male; Pulse; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reference Values; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2002
Reduction in arterial stiffness with angiotensin II antagonist is comparable with and additive to ACE inhibition. American journal of hypertension, 2002, Volume: 15, Issue:4 Pt 1 Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Pressure; Captopril; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan	2002
Influence of AT1 receptor blockade on blood pressure, renal haemodynamics and hormonal responses to intravenous angiotensin II infusion in hypertensive patients. Blood pressure, 2002, Volume: 11, Issue:4 Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Circulation; Renin; Tetrazoles; Valine; Valsartan	2002
Effects of valsartan with or without benazepril on blood pressure, angiotensin II, and endoxin in patients with essential hypertension. Acta pharmacologica Sinica, 2003, Volume: 24, Issue:4 Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardenolides; Digoxin; Female; Humans; Hypertension; Male; Middle Aged; Saponins; Tetrazoles; Valine; Valsartan	2003
Differential effect of acute angiotensin II type 1 receptor blockade on the vascular and adrenal response to exogenous angiotensin II in humans. American journal of hypertension, 2003, Volume: 16, Issue:6 Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Endothelins; Heart Rate; Humans; Hydrocortisone; Injections, Intravenous; Interleukin-6; Male; Renin; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan; Vasoconstrictor Agents	2003
[Effects of angiotensin II on inflammation mediators in healthy subjects]. Deutsche medizinische Wochenschrift (1946), 2003, Nov-21, Volume: 128, Issue:47 Topics: Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cytokines; Humans; Inflammation Mediators; Interleukin-6; Male; Renin-Angiotensin System; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan; Vascular Cell Adhesion Molecule-1	2003
Effect of the angiotensin II antagonist valsartan on sexual function in hypertensive men. Blood pressure. Supplement, 2003, Volume: 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents; Blood Pressure; Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Orgasm; Patient Satisfaction; Penile Erection; Sexual Behavior; Surveys and Questionnaires; Tetrazoles; Valine; Valsartan	2003
Integrating drug pharmacokinetics for phenotyping individual renin response to angiotensin II blockade in humans. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Diet, Sodium-Restricted; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Furosemide; Genetic Variation; Humans; Juxtaglomerular Apparatus; Male; Renin; Renin-Angiotensin System; Reproducibility of Results; Tetrazoles; Valine; Valsartan	2004
Rationale for the use of combination angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker therapy in heart failure. Circulation journal : official journal of the Japanese Circulation Society, 2004, Volume: 68, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Drug Synergism; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Failure; Heart Function Tests; Humans; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Receptors, Angiotensin; Renin; Tetrazoles; Valine; Valsartan	2004
Cardiac angiotensin II participates in coronary microvessel inflammation of unstable angina and strengthens the immunomediated component. Circulation research, 2004, Jun-25, Volume: 94, Issue:12 Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Chymases; Combined Modality Therapy; Coronary Angiography; Coronary Artery Bypass; Coronary Circulation; Cytokines; Female; Gene Expression Profiling; Humans; Male; Microcirculation; Middle Aged; Mitral Valve Stenosis; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Preoperative Care; Ramipril; Renin-Angiotensin System; RNA, Messenger; Serine Endopeptidases; Tetrazoles; Valine; Valsartan; Vasculitis	2004
Simvastatin reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension. Clinica chimica acta; international journal of clinical chemistry, 2004, Volume: 344, Issue:1-2 Topics: Aged; Angiotensin II; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan	2004
Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Aldosterone; Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Drug Synergism; Feedback, Physiological; Fumarates; Humans; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2004
[Combined therapy with quinapril, an ACE inhibitor, and valsartan, a type 1 angiotensin II receptors blocker, for moderate chronic cardiac failure may raise the degree of neurohormonal block and improve 24-h heart rate variability compared to the effect o Terapevticheskii arkhiv, 2005, Volume: 77, Issue:8 Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chronic Disease; Drug Therapy, Combination; Electrocardiography, Ambulatory; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Norepinephrine; Quinapril; Renin; Tetrahydroisoquinolines; Tetrazoles; Valine; Valsartan	2005
The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: influence of the G-protein beta3 subunit (GNB3) C825T polymorphism. Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:3 Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin-1; Genotype; Heterotrimeric GTP-Binding Proteins; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Norepinephrine; Polymorphism, Genetic; Regional Blood Flow; Skin; Tetrazoles; Valine; Valsartan; Vasoconstriction; Vasoconstrictor Agents	2006
[Effects of long term therapy with angiotensin converting enzyme inhibitor quinapril, antagonist of receptors to angiotensin II valsartan, and combination of quinapril and valsartan in patients with moderate chronic heart failure. Main results of the SADK Kardiologiia, 2006, Volume: 46, Issue:7 Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiac Output, Low; Chronic Disease; Drug Therapy, Combination; Exercise Tolerance; Female; Heart Rate; Humans; Male; Middle Aged; Norepinephrine; Quinapril; Tetrahydroisoquinolines; Tetrazoles; Treatment Outcome; Valine; Valsartan; Ventricular Remodeling	2006
Angiotensin II type 1 receptor 1166A/C polymorphism in association with blood pressure response to exogenous angiotensin II. European journal of clinical pharmacology, 2007, Volume: 63, Issue:1 Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Female; Gene Frequency; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2007
Angiotensin type 2 receptor in resistance arteries of type 2 diabetic hypertensive patients. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Atenolol; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan; Vascular Resistance; Vasodilation	2007
Effects of angiotensin receptor blockers on ambulatory plasma Renin activity in healthy, normal subjects during unrestricted sodium intake. American journal of hypertension, 2007, Volume: 20, Issue:8 Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Olmesartan Medoxomil; Prognosis; Radioimmunoassay; Reference Values; Renin; Renin-Angiotensin System; Single-Blind Method; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan	2007
Transforming growth factor-beta1 is associated with kidney damage in patients with essential hypertension: renoprotective effect of ACE inhibitor and/or angiotensin II receptor blocker. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:9 Topics: Administration, Inhalation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan	2008
Contribution of bradykinin B2 receptors to the inhibition by valsartan of systemic and renal effects of exogenous angiotensin II in salt-repleted humans. The Journal of pharmacology and experimental therapeutics, 2010, Sep-01, Volume: 334, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Female; Glomerular Filtration Rate; Humans; Indicators and Reagents; Inulin; Kidney; Male; p-Aminohippuric Acid; Receptor, Bradykinin B2; Renal Circulation; Sodium; Tetrazoles; Valine; Valsartan	2010
Intranasal angiotensin II in humans reduces blood pressure when angiotensin II type 1 receptors are blocked. Hypertension (Dallas, Tex. : 1979), 2014, Volume: 63, Issue:4 Topics: Administration, Intranasal; Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Humans; Hydrocortisone; Male; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2014

Other Studies

208 other study(ies) available for angiotensin ii and valsartan

Article	Year
Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure. Journal of medicinal chemistry, 2004, May-06, Volume: 47, Issue:10 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitive; Computer Simulation; Crystallography, X-Ray; Drug Design; Imidazoles; In Vitro Techniques; Isometric Contraction; Ligands; Liver; Male; Models, Molecular; Molecular Structure; Muscle, Smooth, Vascular; Purines; Pyridines; Quinolines; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Structure-Activity Relationship; Tetrazoles	2004
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems. Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Bridged Bicyclo Compounds, Heterocyclic; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Drug Design; Humans; Intestinal Mucosa; Male; Models, Molecular; Molecular Structure; Pyrazoles; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Stereoisomerism; Structure-Activity Relationship	2008
Expression of components of the RAS during prolonged blockade at different levels in primates. The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antibodies, Monoclonal; Benzazepines; Blood Pressure; Callithrix; Female; Kidney; Liver; Male; Oligopeptides; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Time Factors; Valine; Valsartan	1994
Characterization of contractile endothelin and angiotensin receptors in human resistance arteries: evidence for two endothelin and one angiotensin receptor. Biochemical and biophysical research communications, 1994, Oct-28, Volume: 204, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Azepines; Benzazepines; Bosentan; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indoles; Mammary Arteries; Muscle Contraction; Plasmids; Receptors, Angiotensin; Receptors, Endothelin; Sulfonamides; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Viper Venoms	1994
Postjunctional regulation by angiotensin II of alpha 1-adrenoceptor-mediated pressor responses in the rat. European journal of pharmacology, 1994, Aug-11, Volume: 261, Issue:1-2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Heart Rate; Imidazoles; Male; Neuromuscular Junction; Nitroprusside; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sympathectomy; Synaptic Transmission; Tetrazoles; Valine; Valsartan	1994
Kidney is an important target for the antihypertensive action of an angiotensin II receptor antagonist in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:6 Pt 2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Infusions, Intravenous; Injections; Kidney; Male; Rats; Rats, Inbred SHR; Renin; Tetrazoles; Valine; Valsartan	1993
Binding of valsartan to mammalian angiotensin AT1 receptors. Regulatory peptides, 1995, Nov-10, Volume: 59, Issue:3 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding Sites; Binding, Competitive; Biphenyl Compounds; Callithrix; Cell Membrane; Dogs; Humans; Imidazoles; Liver; Losartan; Molecular Structure; Muscle, Smooth, Vascular; Protein Binding; Rats; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	1995
Left ventricular wall stress and sarcoplasmic reticulum Ca(2+)-ATPase gene expression in renal hypertensive rats: dose-dependent effects of ACE inhibition and AT1-receptor blockade. Cardiovascular research, 1996, Volume: 31, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzazepines; Blotting, Northern; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Heart Ventricles; Hypertension, Renal; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Rats; Rats, Inbred WKY; Sarcoplasmic Reticulum; Tetrazoles; Valine; Valsartan	1996
Drug-induced antisynthetase syndrome. Postgraduate medical journal, 1997, Volume: 73, Issue:857 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Anti-Inflammatory Agents; Arthritis; Autoantibodies; Autoimmune Diseases; Cytoskeleton; Humans; Male; Prednisolone; Pulmonary Fibrosis; Raynaud Disease; Skin Diseases; Syndrome; Tetrazoles; Valine; Valsartan	1997
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models. Arzneimittel-Forschung, 1997, Volume: 47, Issue:5 Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dogs; Enalapril; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Valine; Valsartan	1997
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 3rd communication: hemodynamic effects of valsartan in rats and dogs. Arzneimittel-Forschung, 1997, Volume: 47, Issue:5 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Circulation; Blood Pressure; Bradykinin; Cardiac Output; Dogs; Enalapril; Female; Heart Rate; Hemodynamics; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Tetrazoles; Valine; Valsartan; Vascular Resistance	1997
Role of kinins and angiotensin II in the vasodilating action of angiotensin converting enzyme inhibition in rat renal vessels. Journal of hypertension, 1997, Volume: 15, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Female; Isoquinolines; Kidney; Kinins; Quinapril; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin-Angiotensin System; Tetrahydroisoquinolines; Tetrazoles; Valine; Valsartan; Vasodilation	1997
Role of angiotensin II and bradykinin in experimental diabetic nephropathy. Functional and structural studies. Diabetes, 1997, Volume: 46, Issue:10 Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney; Kidney Glomerulus; Male; Organ Size; Ramipril; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan	1997
Interactions between nitric oxide and angiotensin II on renal cortical and papillary blood flow. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:5 Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Imidazoles; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rats; Rats, Wistar; Regional Blood Flow; Tetrazoles; Valine; Valsartan	1997
Effect of interactions between nitric oxide and angiotensin II on pressure diuresis and natriuresis. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Diuresis; Glomerular Filtration Rate; Imidazoles; Kidney; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pressure; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Renal Circulation; Tetrazoles; Valine; Valsartan	1997
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade. Pharmacology, 1997, Volume: 55, Issue:5 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	1997
Angiotensin II and insulin induce growth of ciliary artery smooth muscle: effects of AT1/AT2 antagonists. Investigative ophthalmology & visual science, 1998, Volume: 39, Issue:11 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Ciliary Arteries; DNA; DNA Replication; Dose-Response Relationship, Drug; Drug Combinations; Insulin; Muscle, Smooth, Vascular; Oligopeptides; Swine; Tetrazoles; Valine; Valsartan	1998
The effect of renin-angiotensin system inhibitors on pro- and anti-inflammatory cytokine production. Immunology, 1998, Volume: 94, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cytokines; Humans; Hypertension; Interleukin-1; Interleukin-6; Lipopolysaccharides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan	1998
AT1 angiotensin II receptor inhibition in pacing-induced heart failure: effects on left ventricular performance and regional blood flow patterns. Journal of cardiac failure, 1998, Volume: 4, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; Exercise Test; Heart Failure; Hemodynamics; Male; Regional Blood Flow; Swine; Tetrazoles; Valine; Valsartan; Vascular Resistance; Ventricular Function, Left	1998
[Myocardial hypertrophy in rabbits with vasorenal arterial hypertension during pharmacological blockade of formation of angiotensin II and its interaction with specific receptors]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Myocardium; Rabbits; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	1999
[Morphofunctional characteristics of myocardial hypertrophy in rabbits with vasorenal arterial hypertension during pharmacological blockade of angiotensin II]. Doklady Akademii nauk, 1999, Volume: 366, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Heart Ventricles; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Organ Size; Rabbits; Tetrazoles; Valine; Valsartan	1999
Valsartan inhibits angiotensin II-stimulated proliferation of smooth muscle cells from human coronary artery. International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:7 Topics: Angiotensin II; Antihypertensive Agents; Arteriosclerosis; Cell Count; Cell Division; Cells, Cultured; Coronary Vessels; Female; Humans; Muscle, Smooth, Vascular; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	1999
Improving outcomes in congestive heart failure: Val-HeFT. Valsartan in Heart Failure Trial. Cardiology, 1999, Volume: 91 Suppl 1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Quality of Life; Tetrazoles; Valine; Valsartan	1999
Angiotensin inhibition and atrial natriuretic peptide release after acute volume expansion in rats with aortocaval shunt. Cardiovascular research, 1999, Volume: 42, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blood Volume; Cyclic GMP; Diuresis; Heart Failure; Male; Myocardium; Ramipril; Rats; Rats, Wistar; Renin-Angiotensin System; Statistics, Nonparametric; Tetrazoles; Valine; Valsartan	1999
Blockade of the renin angiotensin system in heart failure: the potential place of angiotensin II receptor blockers. European heart journal, 2000, Volume: 21, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Heart Failure; Humans; Losartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2000
Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic heart failure. Circulation, 2000, Feb-29, Volume: 101, Issue:8 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Female; Fosinopril; Heart Failure; Humans; Lisinopril; Male; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Treatment Failure; Valine; Valsartan	2000
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation. Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan	2000
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	2000
Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy. The American journal of pathology, 2000, Volume: 157, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Coagulation Factors; Blood Pressure; Cell Line; CHO Cells; Coronary Disease; Coronary Vessels; Cricetinae; Extracellular Matrix Proteins; Heart Ventricles; Humans; Inflammation; Integrin alpha4beta1; Integrins; NF-kappa B; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Lymphocyte Homing; RNA, Messenger; Tetrazoles; Thromboplastin; Transcription Factor AP-1; Valine; Valsartan; Vascular Resistance	2000
Basilar artery remodelling in the genetically hypertensive rat: effects of nitric oxide synthase inhibition and treatment with valsartan and enalapril. Clinical and experimental pharmacology & physiology, 2000, Volume: 27, Issue:8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Basilar Artery; Blood Pressure; Brain; Enalapril; Enzyme Inhibitors; Hypertension; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Stroke; Tetrazoles; Valine; Valsartan; Ventricular Function, Left	2000
[Activation of the renin-angiotensin system and blood pressure variability in rats]. Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:8 Topics: Adrenergic beta-Agonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Catecholamines; Catheters, Indwelling; Femoral Artery; Fourier Analysis; Heart Rate; Infusions, Intravenous; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tachycardia; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2000
Effects of combined angiotensin II and endothelin receptor blockade with developing heart failure: effects on left ventricular performance. Circulation, 2000, Sep-19, Volume: 102, Issue:12 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bosentan; Cardiac Pacing, Artificial; Combined Modality Therapy; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Myocardial Contraction; Norepinephrine; Receptor, Endothelin A; Renin; Sulfonamides; Swine; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left	2000
Osteopontin expression in progressive renal injury in remnant kidney: role of angiotensin II. Kidney international, 2000, Volume: 58, Issue:4 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Disease Models, Animal; Gene Expression; In Situ Hybridization; Kidney; Macrophages; Male; Nephrectomy; Nephritis, Interstitial; Osteopontin; Ramipril; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan	2000
Valsartan in acute myocardial infarction trial (VALIANT): rationale and design. American heart journal, 2000, Volume: 140, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cause of Death; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Humans; Multicenter Studies as Topic; Myocardial Infarction; Odds Ratio; Patient Selection; Proportional Hazards Models; Randomized Controlled Trials as Topic; Research Design; Sample Size; Tetrazoles; Valine; Valsartan	2000
Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis. Kidney international, 2000, Volume: 58, Issue:6 Topics: Age Factors; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Autoradiography; Blood Pressure; Cell Division; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; In Situ Nick-End Labeling; Iodine Radioisotopes; Kidney; Male; Oligopeptides; Organ Size; Osteopontin; Proliferating Cell Nuclear Antigen; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan	2000
[Creatively revised quotation on sale arguments concerning Diovan (valsartan]. Ugeskrift for laeger, 2000, Nov-20, Volume: 162, Issue:47 Topics: Advertising; Angiotensin II; Antihypertensive Agents; Diuretics; Drug Information Services; Humans; Tetrazoles; Valine; Valsartan	2000
Effects of valsartan on angiotensin II-induced migration of human coronary artery smooth muscle cells. Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Arteries; Cell Count; Cell Movement; Cells, Cultured; Coronary Vessels; Humans; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	2000
Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor. British journal of pharmacology, 2001, Volume: 132, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium-Binding Proteins; Calpain; Disease Models, Animal; Gene Expression Regulation; Heart; Heart Rate; Imidazoles; Male; Myocardial Infarction; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription, Genetic; Valine; Valsartan	2001
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation	2001
Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2 Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Cardiovascular Diseases; Fibroblast Growth Factor 2; Heart; Immunohistochemistry; Mineralocorticoid Receptor Antagonists; NF-kappa B; Organ Size; Platelet-Derived Growth Factor; Rats; Receptors, Mineralocorticoid; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tetrazoles; Transcription Factor AP-1; Transforming Growth Factor beta; Valine; Valsartan	2001
Effect of valsartan on angiotensin II-induced plasminogen activator inhibitor-1 biosynthesis in arterial smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Cells, Cultured; Fibrinolysis; Humans; Mammary Arteries; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Tissue Plasminogen Activator; Umbilical Arteries; Valine; Valsartan	2001
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor? Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3 Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2001
Angiotensin II and its metabolites stimulate PAI-1 protein release from human adipocytes in primary culture. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:5 Topics: Adipose Tissue; Adolescent; Adult; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Female; Humans; Middle Aged; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2001
Fetal toxic effects and angiotensin-II-receptor antagonists. Lancet (London, England), 2001, Jul-21, Volume: 358, Issue:9277 Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Female; Humans; Hypertension; Losartan; Pregnancy; Pregnancy Complications, Cardiovascular; Tetrazoles; Valine; Valsartan	2001
Effect of combination of valsartan with benazepril on blood pressure and left ventricular hypertrophy in SHR. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:11 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Drug Therapy, Combination; Hypertension; Hypertrophy, Left Ventricular; Male; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan	2000
[Effects of pathogenetic therapy on blood cholesterol in patients with glomerulonephritis]. Terapevticheskii arkhiv, 2001, Volume: 73, Issue:6 Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anticholesteremic Agents; Antihypertensive Agents; Azathioprine; Captopril; Cholesterol; Creatinine; Cyclophosphamide; Data Interpretation, Statistical; Enalapril; Female; Glomerulonephritis; Humans; Immunosuppressive Agents; Lovastatin; Male; Nephrotic Syndrome; Prednisolone; Retrospective Studies; Tetrazoles; Time Factors; Valine; Valsartan	2001
Effect of valsartan on angiotensin II- and vasopressin-degrading activities in the kidney of normotensive and hypertensive rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2001, Volume: 33, Issue:9 Topics: Aminopeptidases; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Cystinyl Aminopeptidase; Drinking; Glutamyl Aminopeptidase; Hypertension, Renovascular; Kidney; Male; Placebos; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan	2001
Inhibition of the formation or action of angiotensin II reverses attenuated K+ currents in type 1 and type 2 diabetes. The Journal of physiology, 2001, Nov-15, Volume: 537, Issue:Pt 1 Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Carrier Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Electric Conductivity; Isoquinolines; Mutation; Potassium Channels; Quinapril; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Angiotensin, Type 2; Receptors, Cell Surface; Receptors, Leptin; Saralasin; Tetrahydroisoquinolines; Tetrazoles; Valine; Valsartan	2001
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury. Circulation, 2001, Nov-27, Volume: 104, Issue:22 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cell Division; Chemokine CCL2; Femoral Artery; Inflammation; Interleukin-1; Interleukin-6; Leukocyte Common Antigens; Leukocytes; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima; Valine; Valsartan	2001
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan. Journal of hypertension, 2001, Volume: 19, Issue:12 Topics: Acrylates; Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dihydropyridines; Dose-Response Relationship, Drug; Imidazoles; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Thiophenes; Valine; Valsartan	2001
Blockade of angiotensin II type 1 receptors suppressed free radical production and preserved coronary endothelial function in the rabbit heart after myocardial infarction. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:1 Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Endothelium, Vascular; Enzyme Inhibitors; Free Radicals; Hemodynamics; In Vitro Techniques; Lipid Peroxides; Male; Myocardial Infarction; Myocardium; Nitroprusside; omega-N-Methylarginine; Oxygen; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Tiopronin; Valine; Valsartan; Vasodilator Agents; Ventricular Remodeling	2002
High-performance liquid chromatographic analysis of angiotensin II receptor antagonist valsartan using a liquid extraction method. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002, Jan-25, Volume: 766, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Chromatography, High Pressure Liquid; Humans; Receptors, Angiotensin; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence; Tetrazoles; Valine; Valsartan	2002
Valsartan and candesartan can inhibit deteriorating effects of angiotensin II on coronary endothelial function. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2001, Volume: 2, Issue:2 Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagenases; Coronary Vessels; Endothelins; Endothelium, Vascular; Enzyme Precursors; Humans; Male; Matrix Metalloproteinase 1; Plasminogen Activator Inhibitor 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2001
Inhibitory effects of angiotensin II on barosensitive rostral ventrolateral medulla neurons of the rat. Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:12 Topics: Adrenergic alpha-Agonists; Anesthesia; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Glutamic Acid; Imidazoles; Medulla Oblongata; Neurons; Phenylephrine; Pressoreceptors; Pyridines; Rats; Rats, Wistar; Tetrazoles; Time Factors; Valine; Valsartan; Vasoconstrictor Agents	2001
Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP. Journal of hypertension, 2002, Volume: 20, Issue:6 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Female; Imidazoles; Injections, Intravenous; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2002
Effect of angiotensin II antagonism on the regression of kidney disease in the rat. Kidney international, 2002, Volume: 62, Issue:3 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Collagen Type III; Disease Progression; Kidney Diseases; Kidney Glomerulus; Lisinopril; Macrophages; Male; Monocytes; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Tetrazoles; Valine; Valsartan	2002
Ventrolateral medulla AT1 receptors support blood pressure in hypertensive rats. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain Stem; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hypertension; Injections; Kynurenic Acid; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2002
Effects of valsartan on morbidity and mortality in patients with heart failure not receiving angiotensin-converting enzyme inhibitors. Journal of the American College of Cardiology, 2002, Oct-16, Volume: 40, Issue:8 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Female; Heart Failure; Humans; Male; Middle Aged; Quality of Life; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2002
Angiotensin receptor blockers in heart failure: a work in progress. Journal of the American College of Cardiology, 2002, Oct-16, Volume: 40, Issue:8 Topics: Angiotensin II; Heart Failure; Humans; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2002
Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta. Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:10 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Progression; Echocardiography; Enzyme Activation; Heart Failure; Hypertension; Male; Myocardium; Organ Size; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Inbred Dahl; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Function, Left	2002
Biphasic regulation of Na+-HCO3- cotransporter by angiotensin II type 1A receptor. Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Bicarbonates; Calcium; Dose-Response Relationship, Drug; Enzyme Activators; Fluorescent Dyes; Imidazoles; In Vitro Techniques; Intracellular Fluid; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Sodium-Bicarbonate Symporters; Tetrazoles; Valine; Valsartan	2002
Release of preformed Ang II from myocytes mediates angiotensinogen and ET-1 gene overexpression in vivo via AT1 receptor. Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aortic Valve Stenosis; Cardiac Catheterization; Cytoplasm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart; Insulin-Like Growth Factor I; Microscopy, Confocal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stress, Mechanical; Swine; Systole; Tetrazoles; Valine; Valsartan	2002
Comparison of the antagonistic effects of different angiotensin II receptor blockers in human coronary arteries. European journal of heart failure, 2002, Volume: 4, Issue:6 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Base Sequence; Benzimidazoles; Biphenyl Compounds; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Losartan; Male; Middle Aged; Molecular Sequence Data; Probability; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstriction	2002
Appraisal of the role of angiotensin II and aldosterone in ventricular myocyte apoptosis in adult normotensive rat. Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:12 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Down-Regulation; Heart Ventricles; Male; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2002
Aminopeptidase activity in renovascular hypertension. Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1 Topics: Aminopeptidases; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Down-Regulation; Heart Atria; Heart Ventricles; Hypertension; Hypertension, Renovascular; Lung; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan	2003
Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3 Pt 2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Male; Medulla Oblongata; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sodium Chloride; Tetrazoles; Valine; Valsartan	2003
Are angiotensin II receptor antagonists indicated in chronic heart failure? Heart failure monitor, 2002, Volume: 2, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2002
Functional antagonism of different angiotensin II type I receptor blockers in human arteries. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Losartan; Mammary Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2002
Angiotensin receptor subtypes in thin and muscular juxtamedullary efferent arterioles of rat kidney. American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Calcium; Gene Expression Regulation; Juxtaglomerular Apparatus; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Valine; Valsartan	2003
Enhanced angiotensin-mediated responses in the nucleus tractus solitarii of spontaneously hypertensive rats. Brain research bulletin, 2003, May-15, Volume: 60, Issue:3 Topics: Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Glutamic Acid; Heart Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Solitary Nucleus; Species Specificity; Tetrazoles; Valine; Valsartan	2003
Functional comparison of the antagonistic properties of some Angiotensin II type 1 receptor blockers on the contraction elicited by Angiotensin II and thromboxane A2 on human saphenous veins. Journal of cardiovascular pharmacology, 2003, Volume: 42, Issue:1 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Drug Antagonism; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Thromboxane A2, Prostaglandin H2; Saphenous Vein; Tetrazoles; Valine; Valsartan	2003
Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Creatinine; Cyclic N-Oxides; Cyclosporine; Hypertension; Immunosuppressive Agents; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan	2003
Dual inhibition of beta-adrenergic and angiotensin II receptors by a single antagonist: a functional role for receptor-receptor interaction in vivo. Circulation, 2003, Sep-30, Volume: 108, Issue:13 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cell Line; Cells, Cultured; COS Cells; Female; Heart Rate; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Macromolecular Substances; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Propranolol; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, beta; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Valine; Valsartan	2003
[Dosage equivalents of AT1-receptor antagonists available in Germany]. Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44 Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan	2003
Role of superoxide in modulating the renal effects of angiotensin II. Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:6 Topics: Acetophenones; Angiotensin II; Animals; Cyclic N-Oxides; Electrodes; Enzyme Inhibitors; Free Radical Scavengers; Kidney; Kidney Cortex; Male; NADPH Oxidases; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sodium; Spin Labels; Superoxides; Tetrazoles; Valine; Valsartan	2003
Effects of angiotensin II on nitric oxide generation in growing and resting rat aortic endothelial cells. Journal of hypertension, 2003, Volume: 21, Issue:11 Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcimycin; Cell Division; Cells, Cultured; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Ionophores; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation	2003
Effects of angiotensin II on nitric oxide generation in proliferating and quiescent rat coronary microvascular endothelial cells. Hypertension research : official journal of the Japanese Society of Hypertension, 2003, Volume: 26, Issue:9 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Calcimycin; Coronary Vessels; Endothelial Cells; Imidazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Valine; Valsartan	2003
Effects of angiotensin II on sustained outward currents in rat ventricular myocytes. Pflugers Archiv : European journal of physiology, 2004, Volume: 448, Issue:1 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Angiotensin II; Animals; Antihypertensive Agents; Calcium Channel Agonists; Heart Ventricles; Inhibitory Concentration 50; Male; Muscle Cells; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2004
Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation. Circulation research, 2004, Mar-19, Volume: 94, Issue:5 Topics: Angiotensin II; Animals; Calcineurin; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomyopathy, Hypertrophic; Cells, Cultured; Chemokine CCL2; Cyclosporine; Femoral Artery; Gene Expression Regulation; Humans; Hyperplasia; Imidazoles; Macrophages; MAP Kinase Kinase 6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Pyridines; Rats; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Tetrazoles; Transcription, Genetic; Tunica Intima; Valine; Valsartan; Vasculitis	2004
Tissue angiotensin II in the regulation of inflammatory and fibrogenic components of repair in the rat heart. The Journal of laboratory and clinical medicine, 2004, Volume: 143, Issue:1 Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Heart; In Situ Hybridization; Infusions, Parenteral; Male; Myocardium; Nephrectomy; NF-kappa B; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan	2004
Valsartan restores sarcoplasmic reticulum function with no appreciable effect on resting cardiac function in pacing-induced heart failure. Circulation, 2004, Feb-24, Volume: 109, Issue:7 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium Signaling; Calcium-Transporting ATPases; Cardiac Pacing, Artificial; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dobutamine; Dogs; Drug Evaluation, Preclinical; Heart Failure; Myocardial Contraction; Norepinephrine; Phosphorylation; Protein Processing, Post-Translational; Receptors, Adrenergic, beta; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Tachycardia, Ventricular; Tacrolimus Binding Proteins; Tetrazoles; Valine; Valsartan; Ventricular Remodeling	2004
Short-term effects of exogenous angiotensin II on plasma fibrinolytic balance in normal subjects. Clinical and experimental hypertension (New York, N.Y. : 1993), 2004, Volume: 26, Issue:1 Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Circadian Rhythm; Diastole; Dose-Response Relationship, Drug; Fibrinolysis; Fibrinolytic Agents; Germany; Heart Rate; Humans; Hydrocortisone; Male; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Reference Values; Renin; Renin-Angiotensin System; Serine Proteinase Inhibitors; Systole; Tetrazoles; Time Factors; Tissue Plasminogen Activator; Valine; Valsartan; Vasoconstrictor Agents	2004
RhoA activation in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2004, Volume: 27, Issue:4 Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Cells, Cultured; Cyclic AMP; Cyclic GMP; Hypertension; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Stroke; Tetrazoles; Valine; Valsartan	2004
Cardiac angiotensin is upregulated in the hearts of unstable angina patients. Circulation research, 2004, Jun-25, Volume: 94, Issue:12 Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Electrocardiography; Humans; Male; Middle Aged; Models, Cardiovascular; Myocardium; Ramipril; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2004
Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade. Journal of hypertension, 2004, Volume: 22, Issue:8 Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Extracellular Fluid; Kidney; Losartan; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan	2004
Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation. Circulation, 2004, Aug-17, Volume: 110, Issue:7 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Receptor, Angiotensin, Type 2; Superoxides; Tetrazoles; Valine; Valsartan	2004
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression. American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:2 Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan	2005
Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Consciousness; Depression, Chemical; Female; Imidazoles; Injections; Juxtaglomerular Apparatus; Kidney Cortex; Kidney Tubules; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium, Dietary; Systole; Tetrazoles; Valine; Valsartan	2005
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II. Circulation research, 2004, Dec-10, Volume: 95, Issue:12 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan	2004
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells: role of angiotensin II. Circulation research, 2005, Feb-04, Volume: 96, Issue:2 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cells, Cultured; DNA Replication; Gene Expression Regulation; Homeostasis; Humans; Ion Channels; Ion Transport; Magnesium; Membrane Proteins; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Small Interfering; Tetrazoles; Transfection; TRPM Cation Channels; Valine; Valsartan	2005
[The experimental study of captopril and valsartan on the preventing and treatment of diabetic retinopathy in diabetic mice]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2004, Volume: 40, Issue:11 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Male; Mice; Random Allocation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A	2004
[Effects of angiotensin II on peripheral blood endothelial progenitor cells]. Zhonghua nei ke za zhi, 2005, Volume: 44, Issue:1 Topics: Angiotensin II; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Neovascularization, Physiologic; Stem Cells; Tetrazoles; Valine; Valsartan	2005
Cumulative effects of AT1 and AT2 receptor blockade on ischaemia-reperfusion recovery in rat hearts. Pharmacological research, 2005, Volume: 51, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recovery of Function; Tetrazoles; Valine; Valsartan; Ventricular Function, Left	2005
Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. American journal of hypertension, 2005, Volume: 18, Issue:4 Pt 1 Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Extracellular Fluid; Kidney; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Thromboxane B2; Valine; Valsartan	2005
Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist. Biochemical and biophysical research communications, 2005, Jul-15, Volume: 332, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Body Weight; Deoxyguanosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Islets of Langerhans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Tetrazoles; Time Factors; Valine; Valsartan	2005
NAD(P)H-dependent superoxide production in platelets: the role of angiotensin II and protein kinase C. Clinical biochemistry, 2005, Volume: 38, Issue:7 Topics: Aged; Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Benzophenanthridines; Blood Platelets; Female; Humans; Hypertension; Male; Membrane Glycoproteins; Middle Aged; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Phenanthridines; Protein Kinase C; Superoxides; Tetradecanoylphorbol Acetate; Tetrazoles; Valine; Valsartan	2005
Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null mice. Circulation, 2005, Sep-13, Volume: 112, Issue:11 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Gene Deletion; Imidazoles; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	2005
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. American journal of physiology. Cell physiology, 2006, Volume: 290, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Astrocytes; Carboxypeptidases; Cells, Cultured; Cerebellum; Female; Gene Expression Regulation; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2006
[Effects of angiotensin II on extracellular signal-regulated protein kinases signaling pathway in cultured vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats]. Sheng li xue bao : [Acta physiologica Sinica], 2005, Oct-25, Volume: 57, Issue:5 Topics: Angiotensin II; Animals; Cells, Cultured; Dual Specificity Phosphatase 1; Extracellular Signal-Regulated MAP Kinases; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Tetrazoles; Valine; Valsartan	2005
Valsartan abolishes most of the memory-improving effects of intracerebroventricular angiotensin II in rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2005, Volume: 27, Issue:8 Topics: Angiotensin II; Animals; Antihypertensive Agents; Avoidance Learning; Behavior, Animal; Conditioning, Operant; Drinking; Injections, Intraventricular; Male; Maze Learning; Memory; Motor Activity; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2005
Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets. Thrombosis and haemostasis, 2005, Volume: 94, Issue:5 Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Female; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Phosphorylation; Platelet Aggregation; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2005
Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-kappaB-dependent pathway in rat preadipocytes. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:4 Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cell Differentiation; Chemokine CCL2; Humans; Male; NF-kappa B; Nitriles; Obesity; Promoter Regions, Genetic; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Tetrazoles; Thiocarbamates; Transcription, Genetic; Valine; Valsartan	2006
Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:1 Topics: Angiotensin II; Animals; Brain Ischemia; Cell Differentiation; Cells, Cultured; Cognition; Mice; Mice, Inbred C57BL; Neurons; Receptor, Angiotensin, Type 2; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Tetrazoles; Transcriptional Activation; Ubiquitin-Conjugating Enzymes; Valine; Valsartan	2006
Intracellular angiotensin II induces cell proliferation independent of AT1 receptor. American journal of physiology. Cell physiology, 2006, Volume: 291, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cattle; Cell Proliferation; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Rats; Receptor, Angiotensin, Type 1; Tetrazoles; Transfection; Valine; Valsartan	2006
Endothelial progenitor cell differentiation and senescence in an angiotensin II-infusion rat model. Hypertension research : official journal of the Japanese Society of Hypertension, 2006, Volume: 29, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cellular Senescence; Endothelium, Vascular; Hydralazine; Male; Rats; Rats, Wistar; Stem Cells; Telomerase; Tetrazoles; Valine; Valsartan; Vasodilator Agents	2006
Local delivery of angiotensin receptor blocker into the kidney ameliorates progression of experimental glomerulonephritis. Kidney international, 2006, Volume: 70, Issue:9 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Progression; Drug Implants; Female; Gene Expression Regulation; Glomerulonephritis; Isoantibodies; Kidney Glomerulus; Microcirculation; Nephrectomy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2006
Effects of angiotensin II on NO bioavailability evaluated using a catheter-type NO sensor. Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Catheterization; Cyclic N-Oxides; Disease Models, Animal; Hydralazine; Male; Nitric Oxide; Oxidants; Oxidative Stress; Rabbits; Spin Labels; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilator Agents	2006
Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes. Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:6 Topics: Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensins; Cell Differentiation; Gene Expression; Humans; Imidazoles; Mesenchymal Stem Cells; Pyridines; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2006
Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1. Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:2 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Carrier Proteins; Cell Differentiation; Cell Nucleus; Cells, Cultured; DNA Repair; Imidazoles; Inhibitor of Differentiation Protein 1; Ligases; Mice; Nerve Tissue Proteins; Neurites; Neurons; Oligopeptides; Protein Phosphatase 1; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Signal Transduction; Synapses; Tetrazoles; Transcriptional Activation; Tumor Suppressor Proteins; Valine; Valsartan; Vanadates	2007
[Effect of valsatan on hepatocyte growth factor in the airways of asthmatic rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2006, Volume: 8, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Asthma; Bronchi; Hepatocyte Growth Factor; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan	2006
Early lung injury contributes to lung fibrosis via AT1 receptor in rats. Acta pharmacologica Sinica, 2007, Volume: 28, Issue:2 Topics: Angiotensin II; Animals; Apoptosis; Collagen; Lipid Peroxidation; Male; Peptidyl-Dipeptidase A; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Valine; Valsartan	2007
Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide. American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:6 Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Cell Adhesion; Chymases; Disease Models, Animal; Endothelial Cells; Imidazoles; Intestines; Ischemia; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; NADPH Oxidases; Pyridines; Pyrimidinones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Calcitonin Gene-Related Peptide; Reperfusion Injury; Tetrazoles; Valine; Valsartan; Venules	2007
Contribution of different Nox homologues to cardiac remodeling in two-kidney two-clip renovascular hypertensive rats: effect of valsartan. Pharmacological research, 2007, Volume: 55, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Renovascular; Ligation; Male; Malondialdehyde; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Renal Artery; Superoxides; Tetrazoles; Valine; Valsartan; Ventricular Function, Left; Ventricular Remodeling	2007
Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat. American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Cyclic N-Oxides; Lipid Peroxidation; Male; Mitochondria, Heart; NADPH Oxidases; Oxidative Stress; Protein Subunits; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Renin; Spin Labels; Tetrazoles; Valine; Valsartan; Ventricular Remodeling	2007
Novel mechanisms of valsartan on the treatment of acute myocardial infarction through inhibition of the antiadhesion molecule periostin. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:6 Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Cell Adhesion Molecules; Cell Communication; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Random Allocation; Rats; Rats, Inbred Lew; Rats, Wistar; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Remodeling	2007
Angiotensin AT1 receptor blockers suppress ischemia/reperfusion-induced gastric injury in rats. Inflammopharmacology, 2007, Volume: 15, Issue:4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Capillary Permeability; Gastric Mucosa; Hydrogen Peroxide; Losartan; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tetrazoles; Valine; Valsartan	2007
Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence. Cardiovascular research, 2007, Dec-01, Volume: 76, Issue:3 Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Oxidative Stress; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Renin-Angiotensin System; RNA, Small Interfering; Spironolactone; Tetrazoles; Tumor Suppressor Protein p53; Valine; Valsartan	2007
Novel regulatory effect of angiotensin II type 1 receptor-interacting molecule on vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Fluorescence Resonance Energy Transfer; Gene Transfer Techniques; Immunoprecipitation; Muscle, Smooth, Vascular; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Small Interfering; Signal Transduction; Tetrazoles; Transcription, Genetic; Valine; Valsartan	2007
[Expression of angiotensin II type 1 receptor in cervical squamous cell carcinoma and its clinical significance]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2007, Volume: 29, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cervix Uteri; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lymphatic Metastasis; Neoplasm Staging; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Valine; Valsartan; Vascular Endothelial Growth Factor A	2007
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure. Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:12 Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation	2007
Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes. Experimental physiology, 2008, Volume: 93, Issue:5 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Cells, Cultured; DNA; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indicators and Reagents; Matrix Metalloproteinases; Myocytes, Cardiac; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazoles; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic; Valine; Valsartan	2008
Blockade of T-type voltage-dependent Ca2+ channels by benidipine, a dihydropyridine calcium channel blocker, inhibits aldosterone production in human adrenocortical cell line NCI-H295R. European journal of pharmacology, 2008, Apr-28, Volume: 584, Issue:2-3 Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cell Line; Cytochrome P-450 CYP11B2; Dihydropyridines; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Membrane Potentials; Patch-Clamp Techniques; Potassium Chloride; RNA, Messenger; Steroid 11-beta-Hydroxylase; Tetrazoles; Valine; Valsartan	2008
Inhibition of vascular angiotensin-converting enzyme by telmisartan via the peroxisome proliferator-activated receptor gamma agonistic property in rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:12 Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carotid Arteries; Disease Models, Animal; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents	2007
Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats. Journal of hepatology, 2008, Volume: 49, Issue:3 Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Antioxidants; Apoptosis; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan	2008
Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina. Diabetes, 2008, Volume: 57, Issue:8 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Cell Line; Diabetes Mellitus, Experimental; Extracellular Signal-Regulated MAP Kinases; Immunoblotting; Mice; Mice, Inbred C57BL; Neurons; Oncogene Protein v-akt; Phosphorylation; Receptor, Angiotensin, Type 1; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Synaptophysin; Telmisartan; Tetrazoles; Ubiquitination; Valine; Valsartan	2008
[Changes of c-fos, c-jun mRNA expressions in cardiomyocyte hypertrophy induced by angiotensin II and effects of tanshinone II A]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:8 Topics: Abietanes; Angiotensin II; Animals; Cardiomegaly; Gene Expression Regulation; Genes, fos; Genes, jun; Myocytes, Cardiac; Phenanthrenes; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Valine; Valsartan	2008
Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system. Metabolism: clinical and experimental, 2008, Volume: 57, Issue:8 Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Azo Compounds; Blotting, Western; Cell Differentiation; Lipoprotein Lipase; Mice; Microscopy, Phase-Contrast; Pioglitazone; PPAR gamma; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thiazolidinediones; Valine; Valsartan	2008
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation. Stroke, 2008, Volume: 39, Issue:11 Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan	2008
Effects of angiotensin II type 1 receptor blocker on albumin-induced cell damage in human renal proximal tubular epithelial cells. American journal of nephrology, 2009, Volume: 29, Issue:2 Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylglucosaminidase; Albumins; Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cells, Cultured; Deoxyguanosine; Dose-Response Relationship, Drug; Humans; Imidazoles; Kidney Tubules, Proximal; NADPH Oxidases; Oxidative Stress; Tetrazoles; Valine; Valsartan	2009
Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors. American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:5 Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; Insulin; Kidney; Male; Microdialysis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan	2008
Ameliorative effect of Captopril and Valsartan on an animal model of diabetic cardiomyopathy. Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:11 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2008
Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan. International journal of molecular medicine, 2008, Volume: 22, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neutrophil Infiltration; NF-kappa B; Pancreatic Elastase; Rats; Rats, Wistar; Tetrazoles; Ultrasonography; Valine; Valsartan	2008
Angiotensin inhibition stimulates PPARgamma and the release of visfatin. European journal of clinical investigation, 2008, Volume: 38, Issue:11 Topics: Adipocytes; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Benzoates; Blotting, Western; Endothelial Cells; Humans; Intra-Abdominal Fat; Lisinopril; Muscle, Skeletal; Nicotinamide Phosphoribosyltransferase; PPAR gamma; Receptor, IGF Type 1; Rosiglitazone; Telmisartan; Tetrazoles; Thiazolidinediones; Umbilical Veins; Valine; Valsartan	2008
Exaggeration of focal cerebral ischemia in transgenic mice carrying human Renin and human angiotensinogen genes. Stroke, 2009, Volume: 40, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Brain Chemistry; Brain Ischemia; Capillaries; Cerebrovascular Circulation; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Transgenic; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles; Valine; Valsartan	2009
High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin. American journal of nephrology, 2009, Volume: 30, Issue:2 Topics: Angiotensin II; Gene Expression Regulation; Glucose; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Inflammation; Kidney; Mesangial Cells; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Tetrazoles; Valine; Valsartan	2009
Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats. The American journal of pathology, 2009, Volume: 174, Issue:4 Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blotting, Western; Cyclic N-Oxides; DNA, Mitochondrial; Fatty Acids; Fatty Liver; Gene Expression; Immunohistochemistry; Male; Microscopy, Electron, Transmission; Mitochondria; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reverse Transcriptase Polymerase Chain Reaction; Spin Labels; Tetrazoles; Valine; Valsartan	2009
Telmisartan, an angiotensin II type 1 receptor antagonist, attenuates T-type Ca2+ channel expression in neonatal rat cardiomyocytes. European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3 Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Benzoates; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; F-Box Proteins; Flavonoids; Gene Expression Regulation; Heart Rate; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Telmisartan; Tetrazoles; Time Factors; Valine; Valsartan; Zebrafish Proteins	2009
Aliskiren enhances the protective effects of valsartan against cardiovascular and renal injury in endothelial nitric oxide synthase-deficient mice. Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:3 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Diseases; Cardiovascular System; Drug Synergism; Drug Therapy, Combination; Fumarates; Gene Expression; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Superoxides; Tetrazoles; Tunica Intima; Valine; Valsartan	2009
Significance of angiotensin II receptor blockers with high affinity to angiotensin II type 1 receptors for vascular protection in rats. Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:10 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Arteries; Hypertension; Imidazoles; Immunohistochemistry; In Vitro Techniques; Male; Muscle Relaxation; NADPH Oxidases; Peptidyl-Dipeptidase A; Protective Agents; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Tetrazoles; Valine; Valsartan; Vascular Diseases	2009
Valsartan inhibits NPC cell line CNE-2 proliferation and invasion and promotes its sensitivity to radiation. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2009, Volume: 18, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Apoptosis; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Cobalt Radioisotopes; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gamma Rays; Humans; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Radiation Tolerance; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Tumor Cells, Cultured; Valine; Valsartan; Vascular Endothelial Growth Factor A	2009
Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression. Endocrinology, 2009, Volume: 150, Issue:12 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Glucose; Interleukin-1beta; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Prorenin Receptor; Rats; Receptors, Cell Surface; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tetrazoles; Time Factors; Transcription Factor RelA; Valine; Valsartan	2009
Metabolomics in angiotensin II-induced cardiac hypertrophy. Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:2 Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Cardiomegaly; Disease Models, Animal; Fatty Acids; Female; Humans; Hypoxanthine; Linoleic Acids; Male; Metabolomics; Mitochondria, Heart; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sirtuin 1; Survival Rate; Tetrazoles; Valine; Valsartan	2010
[The effect of angiotensin II on phosphoinositide-3 kinase/Akt cascade in cultured fibroblasts derived from patients with hypertrophic scars]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2010, Volume: 26, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; Imidazoles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles; Valine; Valsartan	2010
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity. Pharmacogenetics and genomics, 2010, Volume: 20, Issue:6 Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan	2010
Role of Fosinopril and Valsartan on Klotho Gene Expression Induced by Angiotensin II in Rat Renal Tubular Epithelial Cells. Kidney & blood pressure research, 2010, Volume: 33, Issue:3 Topics: Angiotensin II; Animals; Cell Line; Epithelial Cells; Fosinopril; Gene Expression Regulation; Glucuronidase; Kidney Tubules; Klotho Proteins; Rats; Tetrazoles; Valine; Valsartan	2010
Local angiotensin II aggravates cardiac remodeling in hypertension. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen; Desoxycorticosterone; Dinoprost; Disease Models, Animal; Heart Rate; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan	2010
Radionuclide imaging of angiotensin II type 1 receptor upregulation after myocardial ischemia-reperfusion injury. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:12 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoradiography; Enalapril; Feasibility Studies; Male; Myocardial Reperfusion Injury; Myocardium; Positron-Emission Tomography; Pyridines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tissue Distribution; Valine; Valsartan	2010
Effects of an N-type calcium antagonist on angiotensin II-renin feedback. American journal of nephrology, 2011, Volume: 33, Issue:2 Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan	2011
[Effect of valsartan on vasoconstriction induced by the chronic injury of the adventitia in the rat collared carotid artery]. Zhonghua xin xue guan bing za zhi, 2011, Volume: 39, Issue:1 Topics: Angiotensin II; Animals; Carotid Arteries; Connective Tissue; Male; Oxidative Stress; Rats; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan; Vasoconstriction	2011
Angiotensin II and aldosterone-induced neuronal damage in neurons through an astrocyte-dependent mechanism. Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:6 Topics: Aldosterone; Angiotensin II; Animals; Astrocytes; Cells, Cultured; DNA Damage; Eplerenone; Ganglia, Spinal; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Valine; Valsartan	2011
Inhibition of renin-angiotensin system reverses endothelial dysfunction and oxidative stress in estrogen deficient rats. PloS one, 2011, Mar-29, Volume: 6, Issue:3 Topics: Acetylcholine; Angiotensin II; Animals; Enalapril; Endothelium, Vascular; Estrogens; Female; Free Radical Scavengers; NADPH Oxidases; Nitric Oxide; Ovariectomy; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation	2011
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan	2011
Valsartan inhibits angiotensin II-induced proliferation of vascular smooth muscle cells via regulating the expression of mitofusin 2. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2012, Volume: 32, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Cells, Cultured; Drug Interactions; Gene Expression Regulation; GTP Phosphohydrolases; Male; MAP Kinase Signaling System; Membrane Proteins; Mitochondrial Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan	2012
Valsartan and telmisartan abrogate angiotensin II-induced downregulation of ABCA1 expression via AT1 receptor, rather than AT2 receptor or PPARγ activation. Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6 Topics: Angiotensin II; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Benzoates; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Down-Regulation; Humans; Macrophages; Monocytes; PPAR gamma; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Telmisartan; Tetrazoles; Valine; Valsartan	2012
Deletion of the angiotensin II type 1a receptor prevents atherosclerotic plaque rupture in apolipoprotein E-/- mice. Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; CD36 Antigens; Disease Models, Animal; Disease Progression; Focal Adhesion Kinase 1; Gene Deletion; JNK Mitogen-Activated Protein Kinases; Lipids; Lipoproteins, LDL; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Rupture, Spontaneous; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan	2012
Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan. Journal of pharmacological sciences, 2012, Volume: 119, Issue:2 Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Fumarates; Kidney; Male; Mice; Mice, Inbred C57BL; Renin; RNA, Messenger; Tetrazoles; Valine; Valsartan	2012
Hemodynamic and hormonal changes to dual renin-angiotensin system inhibition in experimental hypertension. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:2 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Fumarates; Heart Rate; Hemodynamics; Hypertension; Kidney; Male; Rats; Renin; Renin-Angiotensin System; Telemetry; Tetrazoles; Valine; Valsartan	2013
[Angiotensin II activates large-conductance Ca(2+)-activated potassium channels in human mesenteric artery smooth muscle cells]. Sheng li xue bao : [Acta physiologica Sinica], 2013, Feb-25, Volume: 65, Issue:1 Topics: Angiotensin II; Humans; Large-Conductance Calcium-Activated Potassium Channels; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan; Vasodilation	2013
Dietary salt intake regulates WNK3-SPAK-NKCC1 phosphorylation cascade in mouse aorta through angiotensin II. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 62, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Mesenteric Arteries; Mice; Mice, Knockout; Phosphorylation; Protein Serine-Threonine Kinases; Sodium, Dietary; Solute Carrier Family 12, Member 2; Tetrazoles; Valine; Valsartan	2013
Angiotensin type 1a receptor-deficient mice develop diabetes-induced cardiac dysfunction, which is prevented by renin-angiotensin system inhibitors. Cardiovascular diabetology, 2013, Nov-12, Volume: 12 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fumarates; Kallikreins; Kininogens; Kinins; Mice; Mice, Knockout; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Ultrasonography; Valine; Valsartan	2013
Angiotensin II downregulates ACE2-mediated enhancement of MMP-2 activity in human cardiofibroblasts. Biochemistry and cell biology = Biochimie et biologie cellulaire, 2013, Volume: 91, Issue:6 Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Fibroblasts; Gene Expression Regulation; Genetic Vectors; Humans; Lentivirus; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; Primary Cell Culture; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents	2013
Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair. PloS one, 2013, Volume: 8, Issue:12 Topics: Angiotensin II; Animals; Apoptosis; Bone Marrow Cells; Cell Transplantation; Coculture Techniques; Echocardiography; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Leukocytes, Mononuclear; Male; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stem Cell Transplantation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A	2013
Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. Journal of molecular and cellular cardiology, 2014, Volume: 66 Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cadherins; Cell Movement; Cells, Cultured; Flavonoids; Gene Expression Regulation; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Oxidation-Reduction; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tetrazoles; Valine; Valsartan	2014
Opiorphin increases blood pressure of conscious rats through renin-angiotensin system (RAS). Peptides, 2014, Volume: 55 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypotension; Hypoxia; Male; Oligopeptides; Rats, Wistar; Renin-Angiotensin System; Salivary Proteins and Peptides; Tetrazoles; Valine; Valsartan	2014
Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity. Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:6 Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blotting, Western; Cells, Cultured; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Immunoenzyme Techniques; Male; Phosphorylation; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Valine; Valsartan	2014
Valsartan ameliorates the constitutive adipokine expression pattern in mature adipocytes: a role for inverse agonism of the angiotensin II type 1 receptor in obesity. Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:7 Topics: 3T3-L1 Cells; Active Transport, Cell Nucleus; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Chlorocebus aethiops; COS Cells; Drug Inverse Agonism; Interleukin-6; Mice; NF-kappa B; Obesity; PPAR gamma; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan	2014
Puerarin inhibits angiotensin II-induced cardiac hypertrophy via the redox-sensitive ERK1/2, p38 and NF-κB pathways. Acta pharmacologica Sinica, 2014, Volume: 35, Issue:4 Topics: Administration, Oral; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertrophy, Left Ventricular; Isoflavones; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Ultrasonography; Valine; Valsartan; Ventricular Remodeling	2014
Humid heat exposure induced oxidative stress and apoptosis in cardiomyocytes through the angiotensin II signaling pathway. Heart and vessels, 2015, Volume: 30, Issue:3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Apoptosis; Disease Models, Animal; Female; Heat Stress Disorders; HEK293 Cells; Hot Temperature; Humans; Humidity; Male; Mice, Inbred C57BL; Myocytes, Cardiac; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Time Factors; Valsartan	2015
Evidence for pericyte origin of TSC-associated renal angiomyolipomas and implications for angiotensin receptor inhibition therapy. American journal of physiology. Renal physiology, 2014, Sep-01, Volume: 307, Issue:5 Topics: Angiomyolipoma; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium; Cell Line, Tumor; Cell Proliferation; Humans; In Vitro Techniques; Kidney; Kidney Neoplasms; Pericytes; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Tuberous Sclerosis; Valine; Valsartan	2014
Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade. Kidney international, 2015, Volume: 87, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Male; Mesangial Cells; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Valsartan; Vascular Endothelial Growth Factor A	2015
Angiotensin II acting on brain AT1 receptors induces adrenaline secretion and pressor responses in the rat. Scientific reports, 2014, Nov-28, Volume: 4 Topics: Adrenal Medulla; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Epinephrine; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan	2014
Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling. American journal of physiology. Heart and circulatory physiology, 2015, Feb-15, Volume: 308, Issue:4 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Endothelium, Vascular; Hydrazines; Hypertension; Indoles; Losartan; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasodilation	2015
Unraveling regulatory mechanisms of atrial remodeling of mitral regurgitation pigs by gene expression profiling analysis: role of type I angiotensin II receptor antagonist. Translational research : the journal of laboratory and clinical medicine, 2015, Volume: 165, Issue:5 Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Remodeling; Down-Regulation; Female; Gene Expression Profiling; Heart Atria; Humans; Male; Middle Aged; Mitral Valve Insufficiency; Renin-Angiotensin System; Swine; Swine, Miniature; Tetrazoles; Translational Research, Biomedical; Up-Regulation; Valine; Valsartan	2015
Angiotensin II-mediated GFR decline in subtotal nephrectomy is due to acid retention associated with reduced GFR. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2015, Volume: 30, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney; Male; Microdialysis; Nephrectomy; Protons; Rats; Rats, Wistar; Sodium Bicarbonate; Tetrazoles; Valine; Valsartan	2015
Suppression of adrenal βarrestin1-dependent aldosterone production by ARBs: head-to-head comparison. Scientific reports, 2015, Jan-29, Volume: 5 Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arrestins; Benzimidazoles; beta-Arrestins; Biphenyl Compounds; CHO Cells; Cricetinae; Cricetulus; GTP-Binding Proteins; Humans; Phosphoproteins; Rats; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation; Valine; Valsartan; Zona Glomerulosa	2015
Valsartan Attenuates Atherosclerosis via Upregulating the Th2 Immune Response in Prolonged Angiotensin II-Treated ApoE(-/-) Mice. Molecular medicine (Cambridge, Mass.), 2015, Feb-09, Volume: 21 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Monoclonal; Apolipoproteins E; Atherosclerosis; Blood Pressure; Body Weight; Disease Models, Animal; Inflammation; Interleukin-5; Lipids; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; T-Lymphocyte Subsets; Th2 Cells; Valsartan	2015
Protective effects of valsartan and benazepril combined with atorvastatin on cardiorenal syndrome in rats. European review for medical and pharmacological sciences, 2015, Volume: 19, Issue:5 Topics: Angiotensin II; Animals; Atorvastatin; Benzazepines; C-Reactive Protein; Cardio-Renal Syndrome; Case-Control Studies; Drug Synergism; Heptanoic Acids; Lipids; Male; Natriuretic Peptide, Brain; Proteinuria; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan	2015
Novel mechanism of cardiac protection by valsartan: synergetic roles of TGF-β1 and HIF-1α in Ang II-mediated fibrosis after myocardial infarction. Journal of cellular and molecular medicine, 2015, Volume: 19, Issue:8 Topics: Angiotensin II; Animals; Blood Vessels; Cardiotonic Agents; Collagen; Fibrosis; Heart Function Tests; Hemodynamics; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Ultrasonography; Valsartan	2015
Pre-treatment with LCZ696, an orally active angiotensin receptor neprilysin inhibitor, prevents ischemic brain damage. European journal of pharmacology, 2015, Sep-05, Volume: 762 Topics: Administration, Oral; Aminobutyrates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Brain; Cerebrovascular Circulation; Drug Combinations; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Neprilysin; Oxidative Stress; Protease Inhibitors; Renin; Sodium; Tetrazoles; Valsartan; Water	2015
Angiotensin II Downregulates MicroRNA-145 to Regulate Kruppel-like Factor 4 and Myocardin Expression in Human Coronary Arterial Smooth Muscle Cells under High Glucose Conditions. Molecular medicine (Cambridge, Mass.), 2015, Jul-14, Volume: 21 Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Coronary Vessels; Gene Expression Regulation; Glucose; Humans; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Rats; Trans-Activators; Tunica Media; Valsartan	2015
Angiotensin II promotes an osteoblast-like phenotype in porcine aortic valve myofibroblasts. Aging clinical and experimental research, 2016, Volume: 28, Issue:2 Topics: Actins; Alkaline Phosphatase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Valve; Bone Morphogenetic Protein 2; Calcinosis; Cell Transdifferentiation; Cells, Cultured; Myofibroblasts; Osteoblasts; Phenotype; Swine; Valsartan; Wnt Signaling Pathway	2016
Angiotensin II Promotes Atherogenesis through upregulating the Expression of Connexin 43 in Dendritic Cells. Cellular and molecular biology (Noisy-le-Grand, France), 2015, Jul-31, Volume: 61, Issue:3 Topics: Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; CD40 Antigens; Cells, Cultured; Connexin 43; Dendritic Cells; Immunohistochemistry; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Smooth Muscle; Up-Regulation; Valsartan	2015
Intrarenal renin-angiotensin system mediates fatty acid-induced ER stress in the kidney. American journal of physiology. Renal physiology, 2016, Mar-01, Volume: 310, Issue:5 Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Blood Glucose; Cell Line; Cell Survival; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fumarates; Gene Expression Regulation; Heat-Shock Proteins; Humans; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice, Inbred C57BL; Palmitic Acid; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Transcription Factor CHOP; Tunicamycin; Unfolded Protein Response; Valsartan	2016
[Valsartan inhibits angiotensin II-Notch signaling of mesangial cells induced by high glucose]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2016, Volume: 32, Issue:1 Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibronectins; Glucose; Mesangial Cells; Rats; Receptor, Notch1; Signal Transduction; Time Factors; Transforming Growth Factor beta; Valsartan	2016
ATRQβ-001 vaccine prevents atherosclerosis in apolipoprotein E-null mice. Journal of hypertension, 2016, Volume: 34, Issue:3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies, Neutralizing; Aorta; Apolipoproteins E; Apoptosis; Atherosclerosis; Chemokine CCL2; Coronary Vessels; Endothelial Cells; Humans; Macrophages; Male; Mice; Mice, Knockout; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Scavenger Receptors, Class E; Vaccines; Valsartan; Vasoconstrictor Agents	2016
Role of angiotensin II and angiotensin type-1 receptor in scorpion venom-induced cardiac and aortic tissue inflammation. Experimental and molecular pathology, 2017, Volume: 102, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Catalase; Creatine Kinase, MB Form; Cytokines; Eosinophils; Glutathione; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred Strains; Myocardium; Neutrophils; Oxidation-Reduction; Oxidative Stress; Receptor, Angiotensin, Type 1; Scorpion Venoms; Valsartan	2017
Hydrochlorothiazide modulates ischemic heart failure-induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats. Cardiovascular therapeutics, 2017, Volume: 35, Issue:2 Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Diuretics; Fibroblasts; Fibrosis; Furosemide; Heart Failure; Heart Ventricles; Hydrochlorothiazide; Male; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Recovery of Function; Signal Transduction; Smad2 Protein; Stroke Volume; Transforming Growth Factor beta1; Valsartan; Ventricular Function, Left; Ventricular Remodeling	2017
Renal Sympathetic Denervation Protects the Failing Heart Via Inhibition of Neprilysin Activity in the Kidney. Journal of the American College of Cardiology, 2017, Oct-24, Volume: 70, Issue:17 Topics: Aminobutyrates; Angiotensin II; Animals; Biphenyl Compounds; Bisoprolol; Blood Pressure; Drug Combinations; Echocardiography; Heart Failure; Kidney; Myocardium; Neprilysin; Nitrites; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin; Reperfusion Injury; Sympathectomy; Tetrazoles; Valsartan; Ventricular Function, Left	2017
Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:1 Topics: Angiotensin II; Animals; Cell Line; Down-Regulation; Humans; Imidazoles; Liver X Receptors; Macrophages; Matrix Metalloproteinase 9; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Pyridines; RAW 264.7 Cells; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Signal Transduction; Valsartan	2018
Transdermal Delivery of AT1 Receptor Antagonists Reduce Blood Pressure and Reveal a Vasodilatory Effect on Kidney Blood Vessels. Current molecular pharmacology, 2018, Volume: 11, Issue:3 Topics: Administration, Cutaneous; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blood Vessels; Humans; Kidney; Losartan; Male; Oligopeptides; Rabbits; Rats, Wistar; Receptor, Angiotensin, Type 1; Reproducibility of Results; Skin Absorption; Valsartan; Vasodilation	2018
Valsartan Alleviates Insulin Resistance in Skeletal Muscle of Chronic Renal Failure Rats. Medical science monitor : international medical journal of experimental and clinical research, 2018, Apr-21, Volume: 24 Topics: Angiotensin II; Animals; Cell Line; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kidney Failure, Chronic; Male; Muscle, Skeletal; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Valsartan	2018
Single-Stranded DNA-Binding Protein 1 Abrogates Cardiac Fibroblast Proliferation and Collagen Expression Induced by Angiotensin II. International heart journal, 2018, Nov-28, Volume: 59, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Cell Proliferation; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; DNA-Binding Proteins; Fibrillar Collagens; Fibrosis; Heart; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Myocardium; Myofibroblasts; Tumor Suppressor Protein p53; Valsartan; Vasoconstrictor Agents	2018
Sacubitril/valsartan (LCZ696) significantly reduces aldosterone and increases cGMP circulating levels in a canine model of RAAS activation. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Feb-01, Volume: 128 Topics: Aldosterone; Aminobutyrates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cross-Over Studies; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Heart Failure; Humans; Male; Natriuretic Peptides; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles; Valsartan	2019
Angiotensin blockade attenuates diabetic nephropathy in hypogonadal adult male rats. Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:8 Topics: Angiotensin II; Angiotensins; Animals; Collagen Type IV; Diabetic Nephropathies; Estradiol; Follicle Stimulating Hormone; Glycated Hemoglobin; Hypogonadism; Kidney; Letrozole; Luteinizing Hormone; Male; NF-kappa B; Organ Size; Oxidative Stress; Rats; Signal Transduction; Testosterone; Transforming Growth Factor beta1; Valsartan	2019
Administration of losartan preserves cardiomyocyte size and prevents myocardial dysfunction in tail-suspended mice by inhibiting p47 Journal of translational medicine, 2019, 08-22, Volume: 17, Issue:1 Topics: Angiotensin II; Animals; Apelin; Apelin Receptors; ATPases Associated with Diverse Cellular Activities; Blood Pressure; Cell Size; Diastole; DNA Helicases; Enzyme Activation; Hindlimb Suspension; Losartan; Male; Mice; Muscle Proteins; Myocardium; Myocytes, Cardiac; Organ Size; Oxidative Stress; Phosphorylation; Tripartite Motif Proteins; Ubiquitin-Protein Ligases; Valsartan	2019
High hydrostatic pressure induces atrial electrical remodeling through angiotensin upregulation mediating FAK/Src pathway activation. Journal of molecular and cellular cardiology, 2020, Volume: 140 Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Atrial Appendage; Atrial Fibrillation; Atrial Remodeling; Cell Line, Tumor; Focal Adhesion Kinase 1; Humans; Hydrostatic Pressure; Mice; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; src-Family Kinases; Up-Regulation; Valsartan	2020
GJA1-20k attenuates Ang II-induced pathological cardiac hypertrophy by regulating gap junction formation and mitochondrial function. Acta pharmacologica Sinica, 2021, Volume: 42, Issue:4 Topics: Angiotensin II; Animals; Cardiomegaly; Connexin 43; Down-Regulation; Gap Junctions; Janus Kinase 2; Male; Membrane Potential, Mitochondrial; Mitochondria; Myocardium; Organelle Biogenesis; Rats, Inbred WKY; Reactive Oxygen Species; Signal Transduction; Tyrphostins; Valsartan	2021
Marein ameliorates Ang II/hypoxia-induced abnormal glucolipid metabolism by modulating the HIF-1α/PPARα/γ pathway in H9c2 cells. Drug development research, 2021, Volume: 82, Issue:4 Topics: Angiotensin II; Animals; Biomarkers; Cell Hypoxia; Cell Line; Chalcones; Coreopsis; Glucose; Hypoxia-Inducible Factor 1, alpha Subunit; Lipid Metabolism; Molecular Structure; Myocytes, Cardiac; PPAR alpha; Valsartan	2021
No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension. Clinical science (London, England : 1979), 2021, 01-29, Volume: 135, Issue:2 Topics: Angiotensin II; Angiotensinogen; Animals; Brain; Brain Stem; Desoxycorticosterone Acetate; Hypertension; Male; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Valsartan	2021
AT1R/GSK-3 Oxidative medicine and cellular longevity, 2020, Volume: 2020 Topics: Angiotensin II; Animals; Apoptosis; Blood Glucose; Cerebral Infarction; Flow Cytometry; Glycogen Synthase Kinase 3 beta; Hypoxia-Ischemia, Brain; In Vitro Techniques; Indoles; Maleimides; Neurons; Oxygen; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazolium Salts; TOR Serine-Threonine Kinases; Valsartan	2020
Time-Dependent Effects of Individual and Combined Treatments With Nebivolol, Lisinopril, and Valsartan on Blood Pressure and Vascular Reactivity to Angiotensin II and Norepinephrine. Journal of cardiovascular pharmacology and therapeutics, 2021, Volume: 26, Issue:5 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Hypertension; Lisinopril; Male; Nebivolol; Norepinephrine; Rats, Inbred SHR; Rats, Wistar; Time; Valsartan; Vascular Resistance; Vasoconstrictor Agents	2021
Sacubitril/Valsartan Decreases Atrial Fibrillation Susceptibility by Inhibiting Angiotensin II-Induced Atrial Fibrosis Through p-Smad2/3, p-JNK, and p-p38 Signaling Pathways. Journal of cardiovascular translational research, 2022, Volume: 15, Issue:1 Topics: Aminobutyrates; Angiotensin II; Animals; Atrial Fibrillation; Biphenyl Compounds; Fibrosis; Rats; Signal Transduction; Valsartan	2022
Blocking angiotensin 2 receptor attenuates diabetic nephropathy via mitigating ANGPTL2/TL4/NF-κB expression. Molecular biology reports, 2021, Volume: 48, Issue:9 Topics: Angiopoietin-Like Protein 2; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Gene Expression; Kidney; Male; NF-kappa B; Protective Agents; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; RNA, Messenger; Streptozocin; Toll-Like Receptor 4; Treatment Outcome; Valsartan	2021
Comparative beneficial effects of nebivolol and nebivolol/valsartan combination against mitochondrial dysfunction in angiotensin II-induced pathology in H9c2 cardiomyoblasts. The Journal of pharmacy and pharmacology, 2021, Oct-07, Volume: 73, Issue:11 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Cell Culture Techniques; Drug Combinations; Heart; Hypertension; Inflammation; Mechanistic Target of Rapamycin Complex 1; Mitochondria; Myoblasts, Cardiac; Myocardium; Nebivolol; Organelle Biogenesis; Oxidative Stress; Rats; Reactive Oxygen Species; Valsartan	2021
Effect of Yiqi Huayu Pinggan Zishen Formula Combined with Valsartan in the Treatment of Hypertension and Its Effect on MMP-9, Ang II, and MCP-1. Computational and mathematical methods in medicine, 2022, Volume: 2022 Topics: Angiotensin II; Antihypertensive Agents; Chemokine CCL2; Drugs, Chinese Herbal; Humans; Hypertension; Matrix Metalloproteinase 9; Syndrome; Valsartan	2022
Angiotensin II Promotes White Adipose Tissue Browning and Lipolysis in Mice. Oxidative medicine and cellular longevity, 2022, Volume: 2022 Topics: Adipose Tissue, Brown; Adipose Tissue, White; AMP-Activated Protein Kinases; Angiotensin II; Animals; Cholesterol, HDL; Cholesterol, LDL; Lipolysis; Male; Mice; Mice, Inbred C57BL; Triglycerides; Valsartan	2022
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes. British journal of pharmacology, 2023, Volume: 180, Issue:1 Topics: Albuminuria; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Humans; Hypertension; Kidney Diseases; Liver; Rats; Renin; Renin-Angiotensin System; RNA, Small Interfering; Valsartan	2023
Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets. Xenobiotica; the fate of foreign compounds in biological systems, 2022, Volume: 52, Issue:6 Topics: Angiotensin II; Animals; Antihypertensive Agents; Callithrix; Dogs; Humans; Macaca fascicularis; Pharmaceutical Preparations; Rats; Retrospective Studies; Valsartan	2022