Page last updated: 2024-08-22

angiotensin ii and thiophenes

angiotensin ii has been researched along with thiophenes in 91 studies

Research

Studies (91)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.20)	18.7374
1990's	34 (37.36)	18.2507
2000's	37 (40.66)	29.6817
2010's	10 (10.99)	24.3611
2020's	8 (8.79)	2.80

Authors

Authors	Studies
Van Nueten, JM	1
Aiyar, N; Edwards, RM; Ezekiel, M; Griffin, E; Keenan, RM; Ohlstein, EH; Ruffolo, RR; Weidley, EF; Weinstock, J	1
Brooks, DP; DePalma, PD; Ruffolo, RR	1
Brooks, DP; Edwards, RM; Gellai, M; Jugus, J; Ohlstein, EH; Ruffolo, RR; Sulpizio, A; Vickery, L; Weinstock, J	1
Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J	1
Barthelmebs, M; Decker, N; Imbs, JL; Krieger, JP; Rochat, C; Stephan, D	1
Laubie, M; Mennecier, P; Verbeuren, TJ	1
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Gleason, JG; Hempel, J; Hill, DT; Keenan, RM; Samanen, J; Weinstock, J	1
Ackerman, NR; Galbraith, W; Gans, KR; Haber, SB; Hewes, WE; Kerr, JS; Roman, RJ; Schmidt, WK; Smith, C	1
Kobinger, W	1
Ciccocioppo, R; Cirillo, R; Massi, M; Polidori, C; Pompei, P	2
Aiyar, N; Baker, E; Brooks, DP; Edwards, RM; Fredrickson, TA; Gellai, M; Ohlstein, EH; Vickery-Clark, L; Weidley, EF; Weinstock, J	1
Brooks, DP; Contino, LC; Edwards, RM; Gowan, C; Short, BG; Trizna, W	1
Arleth, AJ; Ohlstein, EH; Storer, BL; Sung, CP	1
Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, DM; Moore, GJ; Smith, JR; Wahhab, A	1
Brooks, DP; DePalma, PD; Fredrickson, TA; Ruffolo, RR; Spielman, WS	1
Aiyar, N; Edwards, R; Griffin, E; Nambi, P; Samanen, J; Weinstock, J	1
Finkelstein, JA; Franz, RG; Gaitanopoulos, DE; Girard, GR; Hill, DT; Keenan, RM; Morgan, TM; Peishoff, CE; Samanen, JM; Weinstock, J	1
Edwards, RM; Stack, EJ; Trizna, W; Weinstock, J	1
Catalioto, RM; Criscuoli, M; Giachetti, A; Porchia, R; Renzetti, AR; Subissi, A	1
Brunner, HR; Capone, P; Del Re, G; Noël, B; Nussberger, J	1
De'Oliveira, JM; Fisher, ND; Hollenberg, NK; Price, DA	1
Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR	1
Boike, SC; Boyle, DA; Carr, AM; Ilson, BE; Jorkasky, DK; Lundberg, DE; Martin, DE; Tenero, DM	1
Cyronak, MJ; Knox, S; Lundberg, DE; Person, CR	1
Mayeux, PR; Zhang, C	1
Chung, O; Csikós, T; Unger, T	1
Diamond, JA; Gharavi, A; Henzlova, MJ; Machac, J; Phillips, RA; Roychoudhury, D; Travis, A	1
Argenziano, L; Trimarco, B	1
Gavras, H; Gavras, I	1
Levine, B	1
Gradman, AH; Gray, J; Maggiacomo, F; Punzi, H; White, WB	1
Brooks, DP; Gandhi, M; Meyer, TW	1
Shusterman, NH	1
Brooks, DP; Ohlstein, EH; Ruffolo, RR	1
DelGrande, D; Shetty, SS	1
Hollenberg, NK; Laffel, LM; Lansang, MC; Osei, SY; Price, DA	1
Acharya, A; Lei, J; Neugarten, J; Silbiger, S	1
Chikhladze, NM	1
Vidt, DG	1
Ramahi, TM	1
Dargie, HJ; Farmer, R; McDonagh, TA; McMurray, JJ; Morton, JJ; Murdoch, DR	1
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD	1
Guimarães, S; Loio, A; Moura, D; Pinheiro, H; Tavares, P	1
Bahner, U; Elsner, D; Jandeleit-Dahm, K; Kirst, I; Muders, F; Palkovits, M	1
Giatas, N; Golic Grdadolnik, S; Iliodromitis, EK; Keivish, T; Kremastinos, DT; Matsoukas, J; Mavromoustakos, T; Mutule, I; Polevaya, L; Roumelioti, P; Vlahakos, DV; Zoumboulakis, P	1
Sica, DA	1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA	1
Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP; Verdouw, PD	1
McInnes, GT	1
Grove, KL; Smith, MS; Speth, RC	1
Grdadolnik, SG; Matsoukas, J; Mavromoustakos, T; Zoumpoulakis, P	1
Al'-Iazidi, MA; Barsukov, AV; Konev, AV; Kulikov, AN; Shustov, SB	1
Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA	1
Nebieridze, DV; Oganov, RG	1
Krovat, EM; Langer, T	1
Frank, H; Heusser, K; Schmieder, RE; Schobel, HP; Vitkowsky, J	1
Bernardino, JI; Bueso, TS; Jiménez, RT; López, MA; Puig, JG	1
Schieffer, B; Schmidt, B	1
Heusser, K; Raasch, W; Schmieder, RE; Schobel, HP; Vitkovsky, J	1
Heusser, K; Schmieder, RE; Schobel, HP; Vitkovsky, J	1
Dominiak, P; Häuser, W	1
Balt, JC; Belterman, CN; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA	1
Rupp, H	1
Anderson, K; Angermann, CE; Barone, FC; Behr, TM; Berova, M; Coatney, RW; Sackner-Bernstein, JD; Willette, RN	1
Chen, Y; Currie, RW; Ross, BM	1
Campbell, DJ; Esler, MD; Krum, H	1
Chai, W; Danser, AH; Duncker, DJ; Schalekamp, MA; van Kats, JP	1
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K	1
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M	1
Jin, D; Miyazaki, M; Ohzu, M; Takai, S; Tanaka, K	1
Fan, YY; Fujisawa, Y; Hase, N; Hitomi, H; Kiyomoto, H; Kobori, H; Kohno, M; Matsuura, J; Nakano, D; Nishiyama, A; Urata, H	1
Alterman, M; Gallo-Payet, N; Guimond, MO; Hallberg, A; Wallinder, C	1
Cardoso, VN; Faraco, AA; Fernandes, RS; Fernandes, SO; Ferreira, AJ; Foureaux, G; Franca, JR; Fulgêncio, GO; Menezes, GB; Nogueira, BS; Nogueira, JC; Oliveira, GP; Raizada, MK	1
Chen, C; Du, J; Li, HH; Meng, Y; Tian, C	1
Heeba, GH; Mahmoud, ME; Morsy, MA	1
Dessy, C; Duarte, J; Gómez-Gúzman, M; Jiménez, R; León-Gómez, E; Pérez-Vizcaíno, F; Rath, G; Rodríguez-Gómez, I; Romero, M; Sánchez, M; Tamargo, J; Toral, M; Zarzuelo, MJ	1
de Leeuw, PW; Houben, AJ; Kroon, AA; van Twist, DJ	1
Carey, RM; Gildea, JJ; Howell, NL; Keller, SR; Kemp, BA; Padia, SH	1
Claassen, JA; Heerschap, A; Kiliaan, AJ; Roelofs, M; van der Lugt, R; Wiesmann, M	1
Hallberg, A; Hallberg, M; Sävmarker, J	1
Caballero-George, C; Digman, MA; Gratton, E; Planes, N; Vanderheyden, PPML	1
Gaikwad, AB; Sharma, N	1
Heng, CKM; Liao, W; Mei, D; Tan, WSD; Wong, WSF	1
Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G	1
Chan, JSD; Chang, SY; Chenier, I; El-Mortada, MA; Ingelfinger, JR; Liao, MC; Lo, CS; Miyata, KN; Peng, J; Yamashita, M; Zhang, SL; Zhao, XP	1
Bai, HY; Gu, HB; Li, H; Shan, BS; Zhou, X	1
Chiong, M; Hernandez-Fuentes, C; Lavandero, S; Lopez-Crisosto, C; Martinez-Bilbao, J; Norambuena-Soto, I; Parra, V	1
Chan, CCMY; Gan, PXL; Heng, CKM; Liao, W; Mei, D; Tran, QTN; Wong, WSF	1
Berto-Junior, C; Guimarães-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Teixeira-Alves, LR	1

Reviews

12 review(s) available for angiotensin ii and thiophenes

Article	Year
Rudolf Buchheim lecture. Drugs as tools in research on adrenoceptors. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:2 Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Guanidines; Heart Rate; Humans; Imidazoles; Methoxamine; Oxymetazoline; Phenylacetates; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Thiophenes; Xylazine; Yohimbine	1986
Angiotensin II receptor pharmacology and AT1-receptor blockers. Journal of human hypertension, 1999, Volume: 13 Suppl 1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes	1999
Safety and efficacy of eprosartan, a new angiotensin II receptor blocker. American heart journal, 1999, Volume: 138, Issue:3 Pt 2 Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Drug Interactions; Humans; Hypertension; Imidazoles; Thiophenes	1999
Pharmacology of eprosartan, an angiotensin II receptor antagonist: exploring hypotheses from clinical data. American heart journal, 1999, Volume: 138, Issue:3 Pt 2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Disease Models, Animal; Humans; Hypertension; Imidazoles; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes	1999
[Prospects for pharmacological effects on renin-angiotensin and sympathetic nervous systems in patients with arterial hypertension]. Terapevticheskii arkhiv, 2000, Volume: 72, Issue:12 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes	2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications. Postgraduate medicine, 2001, Volume: 109, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan	2001
Pharmacology and clinical efficacy of angiotensin receptor blockers. American journal of hypertension, 2001, Volume: 14, Issue:7 Pt 2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes; Treatment Outcome	2001
Angiotensin II antagonists in systolic blood pressure control. Hospital medicine (London, England : 1998), 2001, Volume: 62, Issue:12 Topics: Acrylates; Angiotensin II; Antihypertensive Agents; Blood Pressure; Delivery of Health Care; Humans; Hypertension; Imidazoles; Renin-Angiotensin System; Systole; Thiophenes	2001
Clinical profile of eprosartan. Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:6 Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Humans; Imidazoles; Renin-Angiotensin System; Thiophenes; Treatment Outcome	2002
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites. Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2	2003
Angiotensin Peptides as AT2 Receptor Agonists. Current protein & peptide science, 2017, Volume: 18, Issue:8 Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Gene Expression; Humans; Hypertension; Inflammation; Kinetics; Peptides; Peptidomimetics; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Sulfonamides; Thiophenes	2017
Angiotensin-(1-9) in hypertension. Biochemical pharmacology, 2022, Volume: 203 Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Imidazoles; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sulfonamides; Thiophenes	2022

Trials

13 trial(s) available for angiotensin ii and thiophenes

Article	Year
Clinical and hormonal effects of the new angiotensin II receptor antagonist LRB081. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:2 Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Catecholamines; Double-Blind Method; Hormones; Humans; Male; Pyrimidinones; Regional Blood Flow; Renin; Thiophenes	1996
Effect of ranitidine on the pharmacokinetics of orally administered eprosartan, an angiotensin II antagonist, in healthy male volunteers. The Annals of pharmacotherapy, 1998, Volume: 32, Issue:3 Topics: Acrylates; Administration, Oral; Adult; Angiotensin II; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Histamine H2 Antagonists; Humans; Imidazoles; Male; Ranitidine; Thiophenes	1998
Effect of long-term eprosartan versus enalapril antihypertensive therapy on left ventricular mass and coronary flow reserve in stage I-II hypertension. Eprosartan Study Group. Current medical research and opinion, 1999, Volume: 15, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Circulation; Double-Blind Method; Enalapril; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Thiophenes	1999
Effect of eprosartan and enalapril in the treatment of elderly hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group. Current medical research and opinion, 1999, Volume: 15, Issue:1 Topics: Acrylates; Age Factors; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Thiophenes	1999
Effects of eprosartan versus enalapril in hypertensive patients on the renin-angiotensin-aldosterone system and safety parameters: results from a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group. Current medical research and opinion, 1999, Volume: 15, Issue:1 Topics: Acrylates; Adult; Aged; Aged, 80 and over; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Consumer Product Safety; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin; Thiophenes	1999
Effect of eprosartan and enalapril in the treatment of black hypertensive patients: subgroup analysis of a 26-week, double-blind, multicentre study. Eprosartan Multinational Study Group. Current medical research and opinion, 1999, Volume: 15, Issue:1 Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Consumer Product Safety; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Thiophenes	1999
Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Eprosartan Study Group. Clinical therapeutics, 1999, Volume: 21, Issue:3 Topics: Acrylates; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Placebos; Prospective Studies; Sex Factors; Thiophenes	1999
ADEPT: Addition of the AT1 receptor antagonist eprosartan to ACE inhibitor therapy in chronic heart failure trial: hemodynamic and neurohormonal effects. American heart journal, 2001, Volume: 141, Issue:5 Topics: Acrylates; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial Natriuretic Factor; Biomarkers; Catheterization, Swan-Ganz; Double-Blind Method; Drug Therapy, Combination; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Prognosis; Prospective Studies; Radionuclide Ventriculography; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Safety; Thiophenes	2001
[Metabolic effects of angiotensin-II receptor blockers]. Kardiologiia, 2002, Volume: 42, Issue:3 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cholesterol; Endothelium, Vascular; Fibrin; Humans; Hypertension; Imidazoles; Male; Receptors, Angiotensin; Thiophenes	2002
Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress. Kidney international, 2003, Volume: 63, Issue:2 Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endocrine Glands; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Imidazoles; Lower Body Negative Pressure; Male; Renal Circulation; Severity of Illness Index; Thiophenes	2003
Elevation of sympathetic activity by eprosartan in young male subjects. American journal of hypertension, 2003, Volume: 16, Issue:8 Topics: Acrylates; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Cross-Over Studies; Double-Blind Method; Electrocardiography; Heart Rate; Humans; Imidazoles; Lower Body Negative Pressure; Male; Muscle, Skeletal; Norepinephrine; Prospective Studies; Stress, Psychological; Sympathetic Nervous System; Thiophenes	2003
AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain. Autonomic neuroscience : basic & clinical, 2003, Aug-29, Volume: 107, Issue:1 Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Baroreflex; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Imidazoles; Male; Prospective Studies; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thiophenes	2003
Losartan increases bradykinin levels in hypertensive humans. Circulation, 2005, Jan-25, Volume: 111, Issue:3 Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes	2005

Other Studies

66 other study(ies) available for angiotensin ii and thiophenes

Article	Year
Antagonism of arachidonic acid hydroperoxide on isolated gastrointestinal tissues as a measure of the inhibition of prostaglandin biosynthesis. Advances in prostaglandin and thromboxane research, 1976, Volume: 1 Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Biological Assay; Bradykinin; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Peroxides; Phenylbutazone; Phenylpropionates; Prostaglandin Antagonists; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Serotonin Antagonists; Thiophenes	1976
Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Calcium; Consciousness; Humans; Imidazoles; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Inbred Strains; Thiophenes; Vasoconstriction	1992
Effect of captopril and the nonpeptide angiotensin II antagonists, SK&F 108566 and EXP3174, on renal function in dogs with a renal artery stenosis. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Acrylates; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Imidazoles; Inulin; Kidney; Losartan; Regional Blood Flow; Renal Artery Obstruction; Tetrazoles; Thiophenes	1992
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Decerebrate State; Enalapril; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Spinal Cord; Tetrazoles; Thiophenes	1992
Characterization of renal angiotensin II receptors using subtype selective antagonists. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes	1992
Effect of tertatolol and of its metabolites and structural analogues in isolated perfused rat kidney vasculature. Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Aorta, Thoracic; Benzazepines; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Renal Circulation; Serotonin; Thiophenes; Vasoconstrictor Agents	1990
5-Hydroxytryptamine-induced vasodilatation in the isolated perfused rat kidney: are endothelial 5-HT1A receptors involved? European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelium, Vascular; Kidney; Male; Nitroglycerin; Papaverine; Piperazines; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Thiophenes; Vasodilation	1991
1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Dogs; Imidazoles; In Vitro Techniques; Indicators and Reagents; Kidney; Molecular Conformation; Molecular Structure; Muscle, Smooth, Vascular; Rabbits; Rats; Receptors, Angiotensin; Structure-Activity Relationship; Thiophenes; Vasoconstriction	1991
Anti-inflammatory and safety profile of DuP 697, a novel orally effective prostaglandin synthesis inhibitor. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1 Topics: Administration, Oral; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Digestive System; Prostaglandins; Rats; Rats, Inbred Strains; Renal Circulation; Thiophenes	1990
The selective angiotensin AT1 receptor antagonist LR-B/081 potently inhibits drinking induced by central injection of angiotensin II in rats. European journal of pharmacology, 1995, Apr-24, Volume: 277, Issue:2-3 Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Drinking; Eating; Imidazoles; Injections, Intraventricular; Lethal Dose 50; Losartan; Male; Milk; Pyrimidinones; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles; Thiophenes	1995
Pharmacology of a potent long-acting imidazole-5-acrylic acid angiotensin AT1 receptor antagonist. European journal of pharmacology, 1995, Sep-05, Volume: 283, Issue:1-3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Binding, Competitive; Calcium; Cattle; Dogs; Dose-Response Relationship, Drug; Humans; Male; Muscle, Smooth, Vascular; Naphthalenes; Rabbits; Rats; Rats, Sprague-Dawley; Thiophenes; Time Factors	1995
SB 203220: a novel angiotensin II receptor antagonist and renoprotective agent. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Captopril; Disease Models, Animal; Kidney Failure, Chronic; Male; Naphthalenes; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes	1995
Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Endothelins; Glycopeptides; Imidazoles; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Thiophenes	1994
Imidazole based non-peptide angiotensin II receptor antagonists. Investigation of the effect of the orientation of the imidazole ring on biological activity. Arzneimittel-Forschung, 1993, Volume: 43, Issue:11 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Losartan; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetrazoles; Thiophenes; Uterine Contraction	1993
Nonpeptide angiotensin II receptor antagonists: potential advantages over ACE inhibitors. Proceedings of the Western Pharmacology Society, 1993, Volume: 36 Topics: Acrylates; Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cough; Dogs; Enalapril; Female; Glomerular Filtration Rate; Imidazoles; Male; Renal Circulation; Thiophenes	1993
Characterization of bovine ovary angiotensin II receptors using subtype-selective antagonists. Pharmacology, 1993, Volume: 46, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cattle; Female; Imidazoles; In Vitro Techniques; Oligopeptides; Ovary; Pyridines; Receptors, Angiotensin; Thiophenes	1993
Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids. Journal of medicinal chemistry, 1993, Jun-25, Volume: 36, Issue:13 Topics: Acrylates; Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; In Vitro Techniques; Models, Molecular; Molecular Sequence Data; Rabbits; Rats; Structure-Activity Relationship; Thiophenes	1993
Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Hydrogen-Ion Concentration; Imidazoles; Kidney; Kinetics; Losartan; Male; Microvilli; Naphthalenes; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Uric Acid	1996
Angiotensin II-induced responses in vascular smooth muscle cells: inhibition by non-peptide receptor antagonists. European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Cells, Cultured; Dinoprostone; DNA; Epoprostenol; Imidazoles; Inositol 1,4,5-Trisphosphate; Leucine; Losartan; Male; Muscle, Smooth, Vascular; Protein Biosynthesis; Pyridines; Pyrimidinones; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Thymidine	1995
Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats. European journal of pharmacology, 1996, Jul-04, Volume: 307, Issue:3 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Carbachol; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Nicotinic Acids; Pyrimidinones; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes	1996
Renal hemodynamic response to an angiotensin II antagonist, eprosartan, in healthy men. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:2 Pt 1 Topics: Acrylates; Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Diet, Sodium-Restricted; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Natriuresis; Reference Values; Renal Circulation; Renin; Thiophenes	1997
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade. Pharmacology, 1997, Volume: 55, Issue:5 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	1997
Determination of SK&F 108566 (Teveten) in human plasma by reversed-phase high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications, 1998, Apr-10, Volume: 707, Issue:1-2 Topics: Acrylates; Angiotensin II; Calibration; Chromatography, High Pressure Liquid; Humans; Imidazoles; Indicators and Reagents; Quality Control; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Thiophenes	1998
Angiotensin II signaling activities the NO-cGMP pathway in rat proximal tubules. Life sciences, 1998, Volume: 63, Issue:4 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cyclic GMP; Imidazoles; Kidney Tubules, Proximal; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Signal Transduction; Thiophenes	1998
Effects of eprosartan on glomerular injury in rats with reduced renal mass. Pharmacology, 1999, Volume: 59, Issue:2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Drug Evaluation, Preclinical; Glomerulosclerosis, Focal Segmental; Imidazoles; Male; Nephrectomy; Proteinuria; Rats; Thiophenes; Vasoconstrictor Agents	1999
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	2000
Effect of angiotensin II antagonist eprosartan on hyperglycemia-induced activation of intrarenal renin-angiotensin system in healthy humans. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:1 Topics: Acrylates; Adult; Angiotensin II; Diabetic Nephropathies; Glomerular Filtration Rate; Hemodynamics; Humans; Hyperglycemia; Imidazoles; Kidney; Male; Middle Aged; Renal Circulation; Renin; Renin-Angiotensin System; Thiophenes	2000
Selective estrogen receptor modulators suppress mesangial cell collagen synthesis. American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:2 Topics: Angiotensin II; Animals; Cell Line, Transformed; Collagen; Endothelin-1; Estrogen Receptor beta; Estrogens; Glomerular Mesangium; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Pyrrolidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Transcription Factor AP-1; Transcription, Genetic; Transforming Growth Factor beta; Up-Regulation	2000
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor? Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3 Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2001
Subcellular localization of angiotensin II in kidney and adrenal. Journal of hypertension, 2001, Volume: 19, Issue:3 Pt 2 Topics: Acrylates; Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Imidazoles; Kidney; Male; Subcellular Fractions; Swine; Thiophenes; Tissue Distribution	2001
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:5 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Ventricles; Imidazoles; Losartan; Male; Presynaptic Terminals; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Angiotensin; Thiophenes; Vasoconstrictor Agents; Ventricular Function	2001
Central inhibition of AT1receptors by eprosartan--in vitro autoradiography in the brain. Pharmacological research, 2001, Volume: 43, Issue:3 Topics: Acrylates; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Blood Pressure; Blood-Brain Barrier; Body Weight; Brain; Heart Rate; Imidazoles; Male; Radiography; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Thiophenes	2001
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:6 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Biochemistry; Biphenyl Compounds; Drug Design; Imidazoles; Irbesartan; Losartan; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peptides, Cyclic; Rabbits; Structure-Activity Relationship; Tetrazoles; Thiophenes	2001
Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan. Journal of hypertension, 2001, Volume: 19, Issue:12 Topics: Acrylates; Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dihydropyridines; Dose-Response Relationship, Drug; Imidazoles; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Thiophenes; Valine; Valsartan	2001
Intrarenal angiotensin II: interstitial and cellular levels and site of production. Kidney international, 2001, Volume: 60, Issue:6 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Imidazoles; Kidney; Swine; Thiophenes; Tissue Distribution	2001
Brain angiotensinergic mediation of enhanced water consumption in lactating rats. American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 282, Issue:3 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Atropine; Brain; Carbachol; Drinking; Female; Imidazoles; Injections, Intraventricular; Lactation; Muscarinic Agonists; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reference Values; Thiophenes	2002
Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist. Journal of pharmaceutical and biomedical analysis, 2002, Apr-01, Volume: 28, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Imidazoles; Models, Molecular; Molecular Conformation; Monte Carlo Method; Nuclear Magnetic Resonance, Biomolecular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Thermodynamics; Thiophenes	2002
[Significance of pharmacological blockade of angiotensin II type I receptors for correction of abnormal 24-hour blood pressure profile depending on its variability in patients with arterial hypertension stage II]. Terapevticheskii arkhiv, 2002, Volume: 74, Issue:2 Topics: Acrylates; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Imidazoles; Male; Receptor, Angiotensin, Type 1; Thiophenes	2002
Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery. Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Rabbits; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Presynaptic; Tetrazoles; Thiophenes	2002
Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification. Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5 Topics: Acrylates; Algorithms; Angiotensin II; Biphenyl Compounds; Databases, Factual; Imidazoles; Lactones; Losartan; Models, Molecular; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfones; Tetrazoles; Thiophenes	2003
[Dosage equivalents of AT1-receptor antagonists available in Germany]. Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44 Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan	2003
Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Electric Stimulation; Heart Failure; Imidazoles; In Vitro Techniques; Male; Osmolar Concentration; Rabbits; Sympathetic Nervous System; Thiophenes	2003
Re: Heusser et al: elevation of sympathetic activity by eprosartan in young male subjects. American journal of hypertension, 2004, Volume: 17, Issue:3 Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Catecholamines; Heart Rate; Humans; Imidazoles; Male; Muscle, Skeletal; Norepinephrine; Stress, Psychological; Sympathetic Nervous System; Thiophenes	2004
Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease. Journal of hypertension, 2004, Volume: 22, Issue:3 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Chemokine CCL2; Down-Regulation; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Immunohistochemistry; Macrophages; Myocardial Contraction; Myocardium; Rats; Rats, Inbred SHR; RNA, Messenger; Thiophenes; Ultrasonography; Vasculitis	2004
Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta. Cell stress & chaperones, 2004, Volume: 9, Issue:1 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Blotting, Western; Electrophoretic Mobility Shift Assay; Heat-Shock Response; Hot Temperature; HSP70 Heat-Shock Proteins; Hydralazine; Hypertension; Imidazoles; Inflammation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; NF-kappa B p50 Subunit; Norepinephrine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Thiophenes; Transcription Factor RelA	2004
Adrenal angiotensin: origin and site of generation. American journal of hypertension, 2005, Volume: 18, Issue:8 Topics: Acrylates; Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Female; Imidazoles; Infusions, Intra-Arterial; Iodine Radioisotopes; Male; Models, Biological; Renin-Angiotensin System; Swine; Thiophenes	2005
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy? Journal of hypertension, 2005, Volume: 23, Issue:10 Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome	2005
Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging. Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:3 Topics: Acrylates; Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Anilides; Arginine; Benzimidazoles; Benzoates; Cells, Cultured; Cellular Senescence; Down-Regulation; Endothelium, Vascular; Humans; Imidazoles; Nitric Oxide; Oxidative Stress; PPAR gamma; Receptor, Angiotensin, Type 1; Signal Transduction; Telmisartan; Thiophenes; Up-Regulation	2008
Chymase inhibition provides pancreatic islet protection in hamsters with streptozotocin-induced diabetes. Journal of pharmacological sciences, 2009, Volume: 110, Issue:4 Topics: Angiotensin II; Animals; Blood Glucose; Chymases; Cricetinae; Diabetes Mellitus, Experimental; Islets of Langerhans; Male; Malondialdehyde; Peptidyl-Dipeptidase A; Streptozocin; Sulfonamides; Thiophenes; Time Factors	2009
Contribution of chymase-dependent angiotensin II formation to the progression of tubulointerstitial fibrosis in obstructed kidneys in hamsters. Journal of pharmacological sciences, 2009, Volume: 111, Issue:1 Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blood Urea Nitrogen; Butyrates; Chymases; Collagen Type I; Cricetinae; Disease Progression; Imidazoles; Kidney; Male; Mesocricetus; Nephritis, Interstitial; Organ Size; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Transforming Growth Factor beta; Ureteral Obstruction	2009
Comparative functional properties of two structurally similar selective nonpeptide drug-like ligands for the angiotensin II type-2 (AT(2)) receptor. Effects on neurite outgrowth in NG108-15 cells. European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Imidazoles; Indoles; Ligands; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurites; Pyridines; rap1 GTP-Binding Proteins; Rats; Receptor, Angiotensin, Type 2; Sulfonamides; Thiazolidinediones; Thiophenes	2013
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2. Investigative ophthalmology & visual science, 2013, Jun-21, Volume: 54, Issue:6 Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular	2013
Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:2 Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation	2015
Ameliorative effect of eprosartan on high-fat diet/streptozotocin-induced early diabetic nephropathy in rats. European journal of pharmacology, 2015, Mar-05, Volume: 750 Topics: Acrylates; Angiotensin II; Animals; Blood Glucose; Catalase; Cholesterol; Collagen Type IV; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation, Enzymologic; Glutathione; Imidazoles; Kidney; Male; Malondialdehyde; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Rats; Rats, Wistar; RNA, Messenger; Streptozocin; Thiophenes; Transforming Growth Factor beta1; Triglycerides	2015
Vascular and Central Activation of Peroxisome Proliferator-Activated Receptor-β Attenuates Angiotensin II-Induced Hypertension: Role of RGS-5. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 358, Issue:1 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Mesenteric Arteries; Mice, Inbred C57BL; Norepinephrine; PPAR-beta; RGS Proteins; Sulfones; Thiazoles; Thiophenes; Vascular Resistance; Vasoconstriction	2016
Acute eprosartan-induced intrarenal vasodilation in hypertensive humans is not influenced by dietary sodium intake or angiotensin II co-infusion. Journal of hypertension, 2016, Volume: 34, Issue:8 Topics: Acrylates; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Essential Hypertension; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Artery; Renal Circulation; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thiophenes; Vasodilation	2016
AT2 Receptor Activation Prevents Sodium Retention and Reduces Blood Pressure in Angiotensin II-Dependent Hypertension. Circulation research, 2016, Aug-05, Volume: 119, Issue:4 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Female; Hypertension; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium; Sulfonamides; Thiophenes	2016
Angiotensin II, hypertension and angiotensin II receptor antagonism: Roles in the behavioural and brain pathology of a mouse model of Alzheimer's disease. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017, Volume: 37, Issue:7 Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Blood Pressure; Brain; Cerebrovascular Circulation; Disease Models, Animal; Hypertension; Imidazoles; Maze Learning; Mice, Transgenic; Spatial Learning; Thiophenes	2017
Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT Biochimica et biophysica acta. General subjects, 2019, Volume: 1863, Issue:5 Topics: Angiotensin II; Animals; Binding Sites; CHO Cells; Cricetulus; Endothelin-1; Fluorescence Resonance Energy Transfer; Humans; Isoxazoles; Ligands; Losartan; Peptides, Cyclic; Protein Aggregates; Receptor, Endothelin A; Thiophenes	2019
Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction. Environmental toxicology and pharmacology, 2020, Volume: 80 Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diminazene; Imidazoles; Ischemia; Kidney; Liver; Male; Myocardium; Oxidative Stress; Peptide Fragments; Peroxidase; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes	2020
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD. Pharmacological research, 2020, Volume: 161 Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Female; Imidazoles; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice, Inbred BALB C; Neutrophils; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Smoke; Sulfonamides; Thiophenes; Tobacco Products	2020
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension. International journal of molecular sciences, 2021, Dec-20, Volume: 22, Issue:24 Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase	2021
Angiotensin II type-2-receptor stimulation ameliorates focal and segmental glomerulosclerosis in mice. Clinical science (London, England : 1979), 2022, 05-27, Volume: 136, Issue:10 Topics: Angiotensin II; Animals; Cathepsin L; Glomerulosclerosis, Focal Segmental; Imidazoles; Kidney Diseases; Male; Mice; Mice, Knockout; Podocytes; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes	2022
AT2 Receptor Stimulation Inhibits Vascular Smooth Muscle Cell Senescence Induced by Angiotensin II and Hyperglycemia. American journal of hypertension, 2022, 10-03, Volume: 35, Issue:10 Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Cellular Senescence; Glucose; Hyperglycemia; Imidazoles; Male; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 2; Sirolimus; Sulfonamides; Superoxides; Thiophenes	2022
Angiotensin II type-2 receptor activation in alveolar macrophages mediates protection against cigarette smoke-induced chronic obstructive pulmonary disease. Pharmacological research, 2022, Volume: 184 Topics: Angiotensin II; Animals; Cigarette Smoking; Imidazoles; Inflammation; Macrophages, Alveolar; Mice; Mitogen-Activated Protein Kinase Phosphatases; NF-kappa B; Nicotiana; Pulmonary Disease, Chronic Obstructive; Receptor, Angiotensin, Type 2; Sirtuin 1; Sulfonamides; Thiophenes	2022
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes. Cell biochemistry and biophysics, 2022, Volume: 80, Issue:4 Topics: Acrylates; Anemia, Sickle Cell; Angiotensin II; Annexin A5; Erythrocytes; Hemoglobin, Sickle; Humans; Imidazoles; Losartan; Phosphatidylserines; Polymerization; Receptor, Angiotensin, Type 1; Thiophenes	2022