angiotensin ii has been researched along with spironolactone in 212 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (50.94) | 18.7374 |
| 1990's | 14 (6.60) | 18.2507 |
| 2000's | 62 (29.25) | 29.6817 |
| 2010's | 26 (12.26) | 24.3611 |
| 2020's | 2 (0.94) | 2.80 |
| Authors | Studies |
|---|---|
| Dean, HG; Lee, MR; Rylett, P | 1 |
| Liddle, GW | 1 |
| Sparks, JC; Susic, D | 2 |
| Rössler, R | 1 |
| Vetter, H; Vetter, W | 1 |
| Aguilera, G; Catt, KJ | 1 |
| Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Kay, AW; Lever, AF; Owen, K; Peart, WS; Robertson, JI | 1 |
| Bartter, FC; Lake, CR; Mitchell, JR; Pool, JL; Rollins, DE; Taylor, AA | 1 |
| Espiner, EA; Mansfield, H; Miles, K | 1 |
| Beckerhoff, R; Furrer, J; Nussberger, J; Siegenthaler, W; Vetter, W | 1 |
| Friedman, A; Johnston, CI; Suthers, MB; Walter, NM | 1 |
| Hara, A; Kawai, C; Komuro, T; Matsunaga, M; Ogino, K; Park, C; Saito, N; Yamamoto, J | 1 |
| Abe, K; Chiba, S; Goto, T; Haruyama, T; Hiwatari, M; Imai, Y; Itoh, T; Omata, K; Otsuka, Y; Sakurai, Y; Sato, K; Sato, M; Yasujima, M; Yoshinaga, K | 1 |
| Ceresa, F | 1 |
| Miyamori, I; Morimoto, S; Saito, Y; Uchida, K; Yamamoto, I | 1 |
| Albano, V; Bellanca, L; Latteri, S; Palazzoadriano, M; Valdes, L | 1 |
| Coleman, TG; Cowley, AW; DeClue, JW; Guyton, AC; McCaa, RE; Norman, RA | 1 |
| Gachályi, B; Káldor, A | 1 |
| Barbour, GL; Day, JO | 1 |
| Erbler, HC | 2 |
| Bergman, B; Kågedal, B; Karlberg, BE; Tegler, L; Tolagen, K | 1 |
| Barrett, JC; Eggena, P; Sambhi, MP; Thananopavarn, C; Tuck, M; Wiedeman, CE | 1 |
| Anderson, GH; Dalakos, TG; Elias, A; Streeten, DH; Tomycz, N | 1 |
| Espiner, EA; Hughes, H; Nicholls, MG; Rogers, T | 1 |
| Abshagen, U; L'age, M; Oelkers, W; Rennekamp, H; Schöneshöfer, M; Spörl, S | 1 |
| Brown, RS; Solomon, RJ | 1 |
| Donker, AJ; Hackeng, WH; Meuwissen, SG; van Vliet, AA | 1 |
| de Caro, G; Epstein, AN; Gentili, L; Massi, M; Pompei, P | 1 |
| Brilla, CG; Weber, KT | 1 |
| Baron, A; Fregly, MJ; Riesselmann, A | 1 |
| Fregly, MJ; Gault, TR; Sumners, C | 1 |
| Jahn, HA; Schohn, DC | 1 |
| Brody, MJ; Janiak, P | 1 |
| Fregly, MJ; Sumners, C | 1 |
| Epstein, AN; Massi, M | 1 |
| Capron, MH; Delarue, C; Leboulenger, F; Netchitailo, P; Perroteau, I; Vaudry, H | 2 |
| Churchill, MC; Churchill, PC; Malvin, RL | 1 |
| Epstein, AN; Nicolaïdis, S; Sakai, RR | 1 |
| Douglas, JG | 1 |
| Drury, PL | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Fraser, R; Kremer, D; Lebel, M; Lever, AF; Morton, JJ; Robertson, JI; Schalekamp, MA; Tree, M; Wilson, A | 1 |
| Brown, JJ; Lever, AF; Robertson, JI | 1 |
| Hänze, S; Pierach, CA; Stark, G | 1 |
| Jahn, H; Kuntzmann, F; Kurtz, T; Réville, P; Stahl, J | 2 |
| Cohen, LA; Farber, L | 1 |
| Arboit, JM; Greenberg, AJ; New, MI; Worthen, HG | 1 |
| Beilin, LJ; Crane, M; Nelson, DH; Schiffman, N | 1 |
| Bános, C; Borbély, L; Radó, JP; Takó, J | 1 |
| Colton, T; Lubbe, WF; Winer, BM | 1 |
| Avenhaus, H; Koczorek, KR | 1 |
| Brackett, NC; Koppel, M; Nixon, WP; Randall, RE | 1 |
| Reimold, EW | 1 |
| Dale, SL; Kahn, PC; Melby, JC; Spark, RF | 1 |
| Allner, R; Dürr, F; Held, H; Kaufmann, W; Meurer, KA; Nieth, H; Schürholz, J; Steiner, B; Streicher, E | 1 |
| Blanton, JH; Coker, AS; Hardin, JG | 1 |
| Hori, S; Masumura, S; Ono, K | 1 |
| Hori, S; Masumura, S; Ono, K; Sato, Y | 1 |
| Goodman, AD; Hartroft, PM; Vagnucci, AH | 1 |
| Crout, JR; Jose, A; Kaplan, NM | 1 |
| Bodin, G; Gillot, F; Rival, JM | 1 |
| Duffy, PA; Frawley, TF; Gonzalez, Y; McGiff, JC; Muzzarelli, RE; Pierce, CE | 1 |
| Bailey, JD; Balis, JU; Hartroft, P; Lynch, MJ; Sutherland, LE | 1 |
| Brown, JJ; Cost, WS; Desmit, EM; Fraser, R; Lever, AF; Robertson, JI | 1 |
| Arant, BS; Brackett, NC; Still, WJ; Young, RB | 1 |
| Dale, SL; Melby, JC; Wilson, TE | 1 |
| Bartter, FC; Delea, CS; Simopoulos, AP | 1 |
| Alexits, K; Káldor, A; Kállay, K; Sebestyén, K | 2 |
| Muller, AF; Scholer, D; Vallotton, MB | 1 |
| Altamura, B; Chiantera, A; De Salvia, F; L'Abbate, N; Lostorto, A; Musti, M | 1 |
| Mendlowitz, M; Naftchi, NE | 1 |
| Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Haywood, E; Lever, AF; Robertson, JI | 1 |
| Spark, RF | 1 |
| Fendler, JP; Legrand, JC; Menard, J; Meyer, P; Milliez, P; Safar, M; Vaysse, J; Weil, B | 1 |
| Fukuchi, S; Nakajima, K; Takenouchi, T | 1 |
| Gantt, C; Grossman, A; Ramanathan, K | 1 |
| Gabrilove, JL; Krakoff, LR; Modlinger, RS; Nicolis, GL | 1 |
| Laidlaw, JC | 1 |
| Horton, R | 1 |
| Endo, J; Kawaguchi, Y; Kono, T; Sakai, T; Yoshimi, T | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Kremer, D; Lever, AF; Robertson, JI | 1 |
| Armstrong, FB; Leach, BE; Muirhead, EE | 1 |
| Alexandre, JM; Corvol, P; Ménard, J; Milliez, P | 1 |
| Fichman, MP; Horton, R; Michelakis, AM | 1 |
| Kuntz, E | 1 |
| Momose, G; Nakada, T; Shigematsu, H; Tateno, Y; Yoshida, T | 1 |
| Speller, PJ; Streeten, DH | 1 |
| Branche, G; Chiles, B; Garnier, C; Kilcoyne, MM; Soland, T; Thomson, GE; Williams, M | 1 |
| Kilcoyne, MM | 1 |
| Blair-West, JR; Ganong, WF; Reid, IA | 1 |
| Alberti, GM; Limal, JM; Postel-Vinay, MC; Rappaport, R; Ricour, C; Royer, P | 1 |
| Hepp, KD | 1 |
| Wisgerhof, M | 1 |
| Chabert, P; Gaillard, RC; Riondel, AM; Vallotton, MB | 1 |
| Gaillard, R; Guelpa-Decorzant, C; Riondel, AM; Vallotton, MB | 1 |
| Ikeda, F; Imura, H; Kono, T; Oseko, F; Tanimura, H | 1 |
| Capron, MH; Delarue, C; Jegou, S; Kusmierek, MC; Leboulenger, F; Leroux, P; Netchitailo, P; Perroteau, I; Tonon, MC; Vaudry, H | 1 |
| Favrod-Coune, CA; Gaillard, RC; Muller, AF; Riondel, AM; Vallotton, MB | 1 |
| Delarue, C; Deraedt, R; Leboulenger, F; Netchitailo, P; Perroteau, I; Philibert, D; Vaudry, H | 1 |
| Chatterjee, TK; Das, S; Ganguly, A; Ghosh, JJ | 1 |
| Cumming, AM; Fraser, R; Leckie, B; Mason, P; Millar, JA; Robertson, JI | 1 |
| Cammarata, PS; Fretland, DJ | 1 |
| Bönner, G; Helber, A; Hummerich, W; Kaufmann, W; Konrads, A; Meurer, KA; Wambach, G | 1 |
| Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C | 1 |
| Abe, K; Arakawa, K; Asano, T; Kawasaki, T; Okumura, M; Sasaki, H | 1 |
| Atkinson, AB; Brown, JJ; Davies, DL; Lever, AF; Robertson, JI | 1 |
| Carpenter, RG; Grossman, SP; Stamoutsos, BA | 1 |
| de Jong, PE; Donker, AJ; Doorenbos, H; Erkelens, DW; van der Hem, GK; van der Wall, E | 1 |
| Fraser, R; Hettiarachchi, J; Morton, JJ; Ramsay, LE | 1 |
| Appay, MD; Bariety, J; Heudes, D; Hinglais, N; Michel, JB; Nicoletti, A; Philippe, M; Sassy-Prigent, C | 1 |
| Mantero, F | 1 |
| Katori, M; Kuribayashi, Y; Majima, M; Mizogami, S; Oh-ishi, S | 1 |
| Campbell, SE; Ratajska, A; Sun, Y; Weber, KT | 1 |
| Brilla, CG; Matsubara, LS; Weber, KT | 1 |
| Hughes, RL; Pilchak, DM; Tordoff, MG | 1 |
| Greene, EL; Hostetter, TH; Kren, S | 1 |
| Igarashi, Y; Kubota, A; Nakagawa, Y; Nasuda, K; Natsume, H; Ogawa, H; Takeuchi, H; Toya, K | 1 |
| Farquharson, CA; Struthers, AD | 1 |
| Puddefoot, JR; Vinson, GP; Xiao, F | 1 |
| Delcayre, C; Desopper, C; Escoubet, B; Heymes, C; Oubénaïssa, A; Robert, V; Silvestre, JS; Swynghedauw, B | 1 |
| Brown, NJ; Donnert, E; Fogo, AB; Freeman, M; Ma, L; Nakamura, I; Nakamura, S; Vaughan, DE | 1 |
| Adler, GK; Kifor, I; Ochoa-Maya, MR; Rennke, HG; Rocha, R; Stier, CT; Williams, GH | 1 |
| Demura, M; Mabuchi, H; Miyamori, I; Takeda, Y; Yoneda, T | 1 |
| Henger, A; Hulter, HN; Krapf, R; Riesen, WF; Tutt, P | 1 |
| Bieringer, M; Breu, V; Dechend, R; Fiebeler, A; Haller, H; Luft, FC; Müller, DN; Park, JK; Schmidt, F; Shagdarsuren, E | 1 |
| Miller, AB; Srivastava, P | 1 |
| Harada, E; Harada, M; Ito, T; Kuwahara, K; Mizuno, Y; Nakagawa, M; Nakagawa, O; Nakamura, S; Nakao, K; Nakayama, M; Ogawa, H; Saito, Y; Shimasaki, Y; Yasue, H; Yoshimura, M | 1 |
| Epstein, M | 1 |
| Greenberg, B | 1 |
| Andreuzzi, B; Gronda, E; Mangiavacchi, M; Municinò, A | 1 |
| Adler, GK; Martinez, DV; Matsumura, M; Ochoa-Maya, M; Oestreicher, E; Rocha, R; Roubsanthisuk, W; Williams, GH | 1 |
| González-Juanatey, JR; Mazón Ramos, P | 1 |
| Imaki, T; Naruse, M; Sato, A; Takagi, S; Takano, K; Tanabe, A; Tsuchiya, K | 1 |
| Amiri, F; Neves, MF; Schiffrin, EL; Touyz, RM; Viel, E; Virdis, A | 1 |
| Ahn, S; Duprez, D; Galanti, L; Gurné, O; Ketelslegers, JM; Robert, A; Rousseau, MF; Van Mieghem, W | 1 |
| Gould, PA; Kaye, DM | 1 |
| Delyani, J; Martin-Berger, CL; McMahon, E; Rocha, R; Scherrer, R; Yang, P | 1 |
| Neves, MF; Schiffrin, EL; Virdis, A | 1 |
| Ageloff, S; Beutler, KT; Brooks, HL; Fenton, RA; Knepper, MA; Masilamani, S; Nielsen, J; Packer, RK; Turban, S | 1 |
| HORKY, K; KUECHEL, O; PAZOUREK, M | 1 |
| DiBianco, R | 1 |
| Adler, GK; Jonasson, L; Martinez-Vasquez, D; Mukasa, K; Oestreicher, EM; Roubsanthisuk, W; Stone, JR | 1 |
| Hishida, A; Yasuda, H; Yonemura, K | 1 |
| MacDonald, TM; Struthers, AD | 1 |
| Black, HR | 1 |
| Hara, Y; Imaki, T; Naruse, M; Nishikawa, T; Sato, A; Takano, K; Tanabe, A; Tsuchiya, K | 1 |
| Aviram, M; Coleman, R; Hamoud, S; Hayek, T; Kaplan, M; Keidar, S; Pavlotzky, E | 1 |
| Akino, M; Denhardt, D; Jia, N; Kitabatake, A; Kon, S; Liu, L; Matsui, Y; Morimoto, J; Okamoto, H; Onozuka, H; Rittling, SR; Uede, T | 1 |
| Dechend, R; Fiebeler, A; Haller, H; Lindschau, C; Luft, FC; Mazak, I; Muller, DN; Park, JK; Pilz, B; Shagdarsuren, E; Viedt, C | 1 |
| Miyamori, I | 1 |
| Dzau, VJ; McMurray, JJ; Pfeffer, MA; Swedberg, K | 1 |
| Cassis, LA; Daugherty, A; Helton, MJ; Howatt, DA; King, VL | 1 |
| Jaffe, IZ; Mendelsohn, ME | 1 |
| Caballero, R; Delpón, E; Gómez, R; Núñez, L; Tamargo, J | 1 |
| Arulmani, U; Chai, W; Danser, AH; Garrelds, IM; Lamers, JM; Schoemaker, RG | 1 |
| Boomsma, F; Lok, DJ; Plokker, HW; van de Wal, RM; van der Horst, FA; van Gilst, WH; van Veldhuisen, DJ; Voors, AA | 1 |
| Amiri, F; Diep, QN; Neves, MF; Schiffrin, EL; Virdis, A | 1 |
| Hyjek, E; Jaggi, JS; McDevitt, MR; Scheinberg, DA; Seshan, SV; Sgouros, G | 1 |
| Bayorh, MA; Eatman, D; Mann, G; Walton, M | 1 |
| Kim, YH; Klein, JD; Murrell, BP; Sands, JM; Tucker, S | 1 |
| Fukushima Kusano, K; Hisamatsu, K; Ishihara, K; Kajiya, M; Miura, A; Miura, D; Miura, R; Morita, H; Nagase, S; Nakamura, K; Ohe, T | 1 |
| Date, T; Kawai, M; Mochizuki, S; Seki, S; Shimizu, M; Taniguchi, I; Taniguchi, M; Yoshida, S | 1 |
| Hori, M; Mano, T; Masuyama, T; Miwa, T; Nishio, M; Nonaka, Y; Ohta, M; Ohtani, T; Okamoto, M; Sakata, Y; Takeda, Y; Yamamoto, K; Yoshida, J | 1 |
| Brown, NJ; Gainer, JV; Luther, JM; Morrow, JD; Murphey, LJ; Vaughan, DE; Yu, C | 1 |
| de Resende, MM; Greene, AS; Kriegel, AJ | 1 |
| Fujita, T; Goto, A; Kobayashi, N; Matsuoka, H; Onozato, ML; Tojo, A | 1 |
| Bao, Y; Jia, R; Yuan, J | 1 |
| Hiroe, M; Imanaka-Yoshida, K; Inada, H; Nishioka, T; Onishi, K; Suzuki, M; Takakura, N; Yoshida, T | 1 |
| Fujita, T; Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Sakata, A; Tsukuda, K | 1 |
| Graciano, ML; Mitchell, KD; Mullins, JJ; Ortiz, RM | 1 |
| Brandes, RP | 1 |
| Fujita, T; Kaneko, T; Matsui, H; Ogura, S; Shimosawa, T; Takenaka, K; Uetake, Y; Wang, H; Yatomi, Y | 1 |
| De Mello, WC; Gerena, Y | 2 |
| Abe, K; Nakao, K; Nakayama, M; Ogawa, H; Saito, Y; Sugiyama, S; Sumida, H; Yamamuro, M; Yasue, H; Yoshimura, M | 1 |
| Brown, NJ; Fogo, AB; Fowler, SM; Kwak, ES; Lea, WB; Luther, JM; Ma, J; Wang, Z | 1 |
| Aoka, Y; Hagiwara, N; Kasanuki, H; Kawana, M; Nagashima, H; Sakurabayashi-Kitade, S | 1 |
| Berden, JH; Kramer, AB; Navis, G; Rops, AL; van den Hoven, MJ; van der Vlag, J; van Goor, H; Waanders, F | 1 |
| Homma, I; Iigaya, K; Kobayashi, Y; Minoura, Y; Onimaru, H | 1 |
| Kinouchi, T; Kitazato, KT; Nagahiro, S; Satomi, J; Shimada, K; Tada, Y; Tamura, T; Yagi, K | 1 |
| Isobe, A; Kimura, T; Li, B; Sakata, M; Takeda, T; Tsuiji, K; Wakabayashi, A; Yaegashi, N | 1 |
| Ahmad, M; Ahmadi, S; Huang, BS; Leenen, FH; White, RA | 1 |
| Edwards, NC; Ferro, CJ; Hammer, F; Hughes, BA; Steeds, RP; Stewart, PM; Townend, JN | 1 |
| Horiuchi, M; Iwanami, J; Jing, F; Min, LJ; Mogi, M; Ohshima, K; Sakata, A; Tsukuda, K | 1 |
| Briones, AM; Callera, GE; He, Y; Montezano, AC; Nguyen Dinh Cat, A; Touyz, RM; Yogi, A | 1 |
| Deguchi, K; Hitomi, H; Kitada, K; Kobori, H; Lei, B; Masaki, T; Minamino, T; Mori, H; Nakano, D; Nishiyama, A | 1 |
| Cai, Y; Jia, LX; Qi, YF; Tang, CS; Wang, X; Wu, SY; Xiao, CS; Yu, YR | 1 |
| Ayuzawa, N; Fujita, T; Ishizawa, K; Kawarazaki, W; Nagase, M; Takeuchi, M; Ueda, K; Yoshida, S | 1 |
| Hamada, J; Kobara, M; Nakata, T; Noda, K; Shiraishi, T; Tanaka, T; Toba, H; Wang, J; Yoshifuji, Y | 1 |
| Ashek, A; Bailey, MA; Bellamy, CO; Flatman, PW; Harmar, AJ; Kenyon, CJ; Menzies, RI; Mullins, JJ; Mullins, LJ | 1 |
| Brown, NJ; Cohen, SE; Fogo, AB; Kim, HS; Luo, P; Luther, JM; Wang, Z | 1 |
| Axelsson, J; Oberg, CM; Rippe, A; Rippe, B | 1 |
| Brem, AS | 1 |
| Jensen, JM; Larsen, T; Lauridsen, TG; Matthesen, SK; Pedersen, EB; Vase, H | 1 |
| Bertorello, AM; Grant, R; Hagaman, JR; Hathaway, CM; Hiller, S; Kakoki, M; Kayashima, Y; Kim, HS; Li, F; Mamenko, M; Matsuki, K; Pochynyuk, OM; Smithies, O; Tomita, H; Xu, L; Zaika, OL | 1 |
| Gabor, A; Leenen, FH | 1 |
| Ahmad, M; Huang, BS; Leenen, FH; White, RA | 1 |
| Gai, L; Xie, Y; Yan, M | 1 |
| Adler, GK; Brown, JM; Garg, R; Garza, AE; Luther, JM; Pojoga, LH; Ruan, DT; Vaidya, A; Williams, GH; Williams, JS | 1 |
| Pilz, S; Tomaschitz, A | 1 |
| Amann, K; Brand, S; Mandel, P; Schupp, N; Zimnol, A | 1 |
| Adler, GK; Khalil, RA; Opsasnick, LA; Pojoga, LH; Reslan, OM; Siddiqui, WT; Williams, GH; Yao, TM | 1 |
| Conte, D; Minas, JN; Nishiyama, A; Ortiz, RM; Thorwald, MA; Vázquez-Medina, JP | 1 |
| Arroyo, JP; Castañeda-Bueno, M; Gamba, G; Lifton, RP; Puthumana, J; Rinehart, J; Rojas-Vega, L; Shibata, S; Yarborough, O; Zhang, J | 1 |
| Gao, X; Li, J; Li, Q; Lu, G; Xiao, Y; Xie, D; Zhai, Y; Zhang, J | 1 |
| Antonelli, J; Bruce, A; Dhaliwal, K; Edwards, C; Finlayson, K; Gaughan, E; Husain, F; Kerai, S; Li, F; Malhotra, V; Mills, B; Moore, A; Pandey, NB; Quinn, TM; Saxena, KN; Shankar-Hari, M; Singh, V; Wadhwa, B | 1 |
| Alcalai, R; Arad, M; Guetta, T; Hochhauser, E; Kornowski, R; Ofek, E; Petrover, Z; Seidman, CE; Seidman, J; Yadin, D | 1 |
15 review(s) available for angiotensin ii and spironolactone
| Article | Year |
|---|---|
Disorders of mineralocorticoid activity.
Topics: 18-Hydroxycorticosterone; Adenoma; Adrenal Glands; Adult; Aldosterone; Angiotensin II; Blood Specimen Collection; Brain Neoplasms; Circadian Rhythm; Dexamethasone; Diagnosis, Differential; Evoked Potentials; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Intestinal Mucosa; Mineralocorticoids; Models, Biological; Posture; Radionuclide Imaging; Renin; Spironolactone; Tomography, X-Ray Computed; Ultrasonography | 1985 |
Aldosterone: review of its physiology and diagnostic aspects of primary aldosteronism.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Desoxycorticosterone; Humans; Hyperaldosteronism; Hyperplasia; Hypertension; Hypokalemia; Potassium; Radiography; Renin; Sodium; Spironolactone | 1973 |
[Renin-angiotensin-aldosterone system in essential hypertension].
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Male; Middle Aged; Renin; Spironolactone | 1973 |
[Hepatogenous (secondary) aldosteronism (author's transl)].
Topics: Aldosterone; Angiotensin II; Chronic Disease; Esophageal and Gastric Varices; Hepatitis; Hepatitis A; Humans; Hyperaldosteronism; Liver Diseases; Liver Function Tests; Portacaval Shunt, Surgical; Renin; Spironolactone; Water; Water-Electrolyte Balance | 1974 |
Heart failure drugs: what's new?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Drug Therapy, Combination; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Receptors, Angiotensin; Spironolactone | 2000 |
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart Failure; Humans; Hypertension; Losartan; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan | 2001 |
Aldosterone as a determinant of cardiovascular and renal dysfunction.
Topics: Aldosterone; Angiotensin II; Animals; Cardiovascular Diseases; Endothelium, Vascular; Fibrosis; Humans; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Nitric Oxide; Potassium; Randomized Controlled Trials as Topic; Sodium; Spironolactone | 2001 |
[Arrhythmia risk stratification in patients with heart failure according to drug treatment and its effects].
Topics: Adrenergic beta-Antagonists; Amiodarone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Death, Sudden, Cardiac; Diuretics; Heart Failure; Humans; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Pacemaker, Artificial; Prognosis; Randomized Controlled Trials as Topic; Risk; Risk Assessment; Spironolactone; Vasodilator Agents | 2001 |
Clinical treatment regimens for chronic heart failure: a review.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; Diuretics; Heart Failure; Humans; Hydralazine; Isosorbide Dinitrate; Pacemaker, Artificial; Spironolactone; Vasodilator Agents | 2002 |
Update on therapy for heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Heart Failure; Humans; Spironolactone | 2003 |
Review of aldosterone- and angiotensin II-induced target organ damage and prevention.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Endothelium, Vascular; Eplerenone; Humans; Kidney; Mineralocorticoid Receptor Antagonists; Myocardium; Spironolactone | 2004 |
Evolving role of aldosterone blockers alone and in combination with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in hypertension management: a review of mechanistic and clinical data.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Eplerenone; Humans; Hypertension; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone | 2004 |
[Involvement of Aldosterone and mineralocorticoid receptor in pathogenesis of cardiovascular diseases].
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Angiotensin II; Cardiovascular Diseases; Fibrosis; Humans; Hydrocortisone; Mineralocorticoid Receptor Antagonists; Myocardium; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone | 2004 |
Which inhibitor of the renin-angiotensin system should be used in chronic heart failure and acute myocardial infarction?
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Heart Failure; Humans; Hypotension; Mineralocorticoid Receptor Antagonists; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Spironolactone; Ventricular Dysfunction, Left | 2004 |
Angiotensin II, angiotensin II antagonists and spironolactone and their modulation of cardiac repolarization.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Humans; Myocardial Contraction; Receptor, Angiotensin, Type 2; Spironolactone | 2005 |
16 trial(s) available for angiotensin ii and spironolactone
| Article | Year |
|---|---|
Renin-aldosterone profiling in hypertension.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Clinical Trials as Topic; Diagnosis, Differential; Diuretics; Dopamine beta-Hydroxylase; Humans; Hyperaldosteronism; Hypertension; Norepinephrine; Propranolol; Renin; Sodium Chloride Symporter Inhibitors; Spironolactone; Triamterene | 1977 |
Response of blood pressure and the renin-angiotensin-aldosterone axis to hypotensive therapy: comparison of propranolol with spironolactone.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Propranolol; Renin; Spironolactone | 1977 |
[Spironolactone-induced changes of the renin-angiotensin-aldosterone system and blood pressure lowering in essential hypertension].
Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Humans; Hypertension; Renin; Spironolactone | 1977 |
A comparison between spironolactone and hydrochlorothiazide with and without alpha-methyldopa in the treatment of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone | 1978 |
Controlled treatment of primary hypertension with propranolol and spironolactone. A crossover study with special reference to initial plasma renin activity.
Topics: Adult; Aldosterone; Angiotensin II; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Posture; Potassium; Propranolol; Renin; Sodium; Spironolactone | 1976 |
Antihypertensive actions of diuretics. Comparative study of an aldosterone antagonist and a thiazide, alone and together.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure Determination; Blood Volume Determination; Clinical Trials as Topic; Humans; Hydrochlorothiazide; Hypertension; Norepinephrine; Placebos; Potassium; Spironolactone | 1968 |
18-Hydroxy-deoxycorticosterone in human hypertension.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Blood Pressure; Catheterization; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Dexamethasone; Humans; Hypertension; Liver Extracts; Mass Spectrometry; Mineralocorticoids; Radioisotope Dilution Technique; Renin; Sodium; Spironolactone; Tritium | 1971 |
Effect of spironolactone on aldosterone regulation in man.
Topics: Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Corticosterone; Humans; Hydrocortisone; Male; Potassium; Renin; Sodium; Spironolactone | 1980 |
Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure.
Topics: Aged; Angiotensin I; Angiotensin II; Chronic Disease; Cross-Over Studies; Diuretics; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Spironolactone; Vasodilation | 2000 |
Beneficial neurohormonal profile of spironolactone in severe congestive heart failure: results from the RALES neurohormonal substudy.
Topics: Aged; Aged, 80 and over; Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Treatment Outcome | 2002 |
Effects of spironolactone during an angiotensin II receptor blocker treatment on the left ventricular mass reduction in hypertensive patients with concentric left ventricular hypertrophy.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Female; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Tetrazoles; Ventricular Remodeling | 2006 |
Angiotensin II induces interleukin-6 in humans through a mineralocorticoid receptor-dependent mechanism.
Topics: Adult; Aldosterone; Angiotensin II; Cross-Over Studies; Diet, Sodium-Restricted; Double-Blind Method; Female; Humans; Hydroxycorticosteroids; Infusions, Intravenous; Interleukin-6; Male; Mineralocorticoid Receptor Antagonists; Oxidative Stress; Receptors, Mineralocorticoid; Spironolactone | 2006 |
The effect of spironolactone upon corticosteroid hormone metabolism in patients with early stage chronic kidney disease.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Female; Humans; Hydrocortisone; Kidney Failure, Chronic; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Renal Insufficiency, Chronic; Renin; Spironolactone; Tetrahydrocortisol | 2010 |
Effect of amiloride and spironolactone on renal tubular function and central blood pressure in patients with arterial hypertension during baseline conditions and after furosemide: a double-blinded, randomized, placebo-controlled crossover trial.
Topics: Aged; Aldosterone; Amiloride; Angiotensin II; Aquaporin 2; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Epithelial Sodium Channels; Female; Furosemide; Humans; Hypertension; Kidney Tubules; Male; Middle Aged; Potassium; Pulse Wave Analysis; Renin; Sodium; Spironolactone | 2013 |
Human interventions to characterize novel relationships between the renin-angiotensin-aldosterone system and parathyroid hormone.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Captopril; Diuretics; Dose-Response Relationship, Drug; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Parathyroid Glands; Parathyroid Hormone; Renin-Angiotensin System; Spironolactone; Vasoconstrictor Agents; Vitamin D | 2014 |
Phase 2 randomised placebo-controlled trial of spironolactone and dexamethasone versus dexamethasone in COVID-19 hospitalised patients in Delhi.
Topics: Aldosterone; Angiotensin II; COVID-19; COVID-19 Drug Treatment; Dexamethasone; Humans; Randomized Controlled Trials as Topic; SARS-CoV-2; Spironolactone; Treatment Outcome; von Willebrand Factor | 2023 |
181 other study(ies) available for angiotensin ii and spironolactone
| Article | Year |
|---|---|
Brain tyrosine hydroxylase activity and systolic blood pressure in rats treated with either deoxycorticosterone and salt or angiotensin.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Desoxycorticosterone; Male; Rats; Sodium Chloride; Spironolactone; Time Factors; Tyrosine 3-Monooxygenase | 1976 |
The Distinguished Lecture. Is hypertension essential?
Topics: Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Dehydroepiandrosterone; Humans; Hypertension; Hypertension, Renal; Mineralocorticoids; Natriuresis; Norepinephrine; Patient Compliance; Phenoxybenzamine; Renal Artery Obstruction; Renin; Saralasin; Spironolactone | 1975 |
Differentiation of nephrotensin from the renin angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies; Atropine; Biological Assay; Blood Pressure; Carbon Tetrachloride Poisoning; Hypertension, Renal; Kidney Diseases; Male; Mercury; Nephrectomy; Norepinephrine; Pentolinium Tartrate; Peptides; Rats; Renin; Spironolactone; Teprotide; Vasoconstrictor Agents | 1975 |
[Plasma-aldosterone and renin activity in Bartter's syndrome (author's transl)].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Bartter Syndrome; Dexamethasone; Glucocorticoids; Humans; Hyperaldosteronism; Male; Potassium; Renin; Sodium; Spironolactone; Time Factors | 1975 |
Control of plasma aldosterone in a patient with Conn's syndrome before and during spironolactone medication.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Female; Humans; Hydrocortisone; Hyperaldosteronism; Middle Aged; Renin; Secretory Rate; Spironolactone | 1975 |
Loci of action of regulators of aldosterone biosynthesis in isolated glomerulosa cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide; Angiotensin II; Animals; Corticosterone; Desoxycorticosterone; Dogs; In Vitro Techniques; Potassium; Progesterone; Rats; Spironolactone | 1979 |
Results of adrenal surgery in patients with hypertension, aldosterone excess, and low plasma renin concentration.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Aged; Angiotensin II; Blood Pressure; Carbon Dioxide; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone; Urea | 1975 |
Pathophysiological studies on hypertension induced in rats by kidney extract and salt.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Volume; Body Fluids; Hexamethonium Compounds; Hypertension; Kidney; Male; Nephrectomy; Norepinephrine; Rats; Renin; Sodium Chloride; Spironolactone; Tissue Extracts; Water-Electrolyte Balance | 1979 |
The role of renal prostaglandin E and kallikrein in pathogenesis of essential hypertension.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Furosemide; Humans; Hypertension; Indomethacin; Kallikreins; Kidney; Male; Middle Aged; Posture; Potassium; Prostaglandins E; Renin; Sodium; Spironolactone | 1979 |
[Therapy of primary hyperaldosteronism].
Topics: Adrenalectomy; Aldosterone; Androgen Antagonists; Angiotensin II; Estrogen Antagonists; Female; Humans; Hyperaldosteronism; Male; Renin; Spironolactone | 1979 |
[Physiopathological study of low renin essential hypertension].
Topics: Adult; Angiotensin II; Blood Pressure; Humans; Hyperaldosteronism; Hypertension; Middle Aged; Renin; Spironolactone | 1977 |
Drug-induced variations of the renin-angiotensin-aldosterone system in rats. I. Diuretics.
Topics: Aldosterone; Angiotensin II; Animals; Diuresis; Diuretics; Male; Potassium; Rats; Renin; Sodium; Spironolactone; Triamterene | 1977 |
Subpressor angiotensin infusion, renal sodium handling, and salt-induced hypertension in the dog.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Furosemide; Hypertension; Infusions, Parenteral; Natriuresis; Renin; Sodium Chloride; Spironolactone; Time Factors | 1978 |
Effect of clonidine (Haemiton) on plasma renin level and angiotensin sensitivity in man.
Topics: Adult; Angiotensin II; Blood Pressure; Clonidine; Female; Humans; Male; Middle Aged; Renin; Spironolactone | 1978 |
Asymptomatic Bartter's syndrome.
Topics: Angiotensin II; Bartter Syndrome; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypokalemia; Indomethacin; Kidney; Kidney Concentrating Ability; Magnesium; Male; Middle Aged; Potassium; Sodium; Spironolactone | 1978 |
Effect of spironolactone and its main metabolite canrenone on the renin-angiotensin-aldosterone-system during long-term treatment in rats.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Animals; Canrenone; Dose-Response Relationship, Drug; Male; Pregnadienes; Rats; Renin; Spironolactone; Time Factors; Water-Electrolyte Balance | 1979 |
A circulating renin activator in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Contraceptives, Oral; Diuretics; Enzyme Activation; Functional Laterality; Haplorhini; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kinetics; Renal Artery Obstruction; Renin; Sodium; Spironolactone | 1975 |
Diuretic therapy and response of essential hypertension to saralasin.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Saralasin; Spironolactone; Stimulation, Chemical | 1977 |
Effect of potassium-sparing diuretics on the renin-angiotensin-aldosterone system and potassium retention in heart failure.
Topics: Adult; Aged; Aldosterone; Amiloride; Angiotensin II; Digoxin; Female; Furosemide; Heart Failure; Humans; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone; Urea | 1976 |
[Endogenous steroid balance under treatment with spironolactone].
Topics: Aldosterone; Angiotensin II; Humans; Male; Renin; Spironolactone | 1976 |
Bartter's syndrome. New insights into pathogenesis and treatment.
Topics: Adult; Aldosterone; Angiotensin II; Bartter Syndrome; Blood Volume; Female; Humans; Hyperaldosteronism; Kidney; Kidney Concentrating Ability; Potassium Chloride; Pressoreceptors; Propranolol; Renin; Sodium; Spironolactone | 1975 |
Efficacy of low-dose captopril in addition to furosemide and spironolactone in patients with decompensated liver disease during blunted diuresis.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Captopril; Creatinine; Cyclic GMP; Diuresis; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Furosemide; Humans; Kidney; Liver; Liver Cirrhosis; Male; Middle Aged; Renal Dialysis; Renin; Sodium; Spironolactone | 1992 |
Central tachykinin injection potently suppresses the need-free salt intake of the female rat.
Topics: Aldosterone; Angiotensin II; Animals; Captopril; Down-Regulation; Drinking; Eating; Eledoisin; Female; Injections, Intraperitoneal; Injections, Intraventricular; Kassinin; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Sodium, Dietary; Spironolactone; Sucrose; Tachykinins | 1992 |
Reactive and reparative myocardial fibrosis in arterial hypertension in the rat.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen; Disease Models, Animal; Fibrosis; Hypertension, Renovascular; Male; Myocardium; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Spironolactone | 1992 |
Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Clonidine; Cold Temperature; Drinking; Drug Therapy, Combination; Eating; Epinephrine; Hypertension; Kidney; Male; Norepinephrine; Organ Size; Rats; Rats, Inbred Strains; Renin; Spironolactone; Time Factors; Urination | 1991 |
Potentiation of angiotensin II-induced drinking by glucocorticoids is a specific glucocorticoid type II receptor (GR)-mediated event.
Topics: Androstanols; Angiotensin II; Animals; Carbachol; Cerebral Ventricles; Dexamethasone; Dose-Response Relationship, Drug; Drinking Behavior; Drug Synergism; Injections, Intraventricular; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Reference Values; Spironolactone; Time Factors | 1991 |
Effects of a potassium-sparing/thiazide diuretic combination on cardiovascular reactivity to vasopressor agents.
Topics: Angiotensin II; Anuria; Benzothiadiazines; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Combinations; Female; Heart Atria; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Norepinephrine; Potassium; Pulmonary Wedge Pressure; Renal Dialysis; Sodium Chloride Symporter Inhibitors; Spironolactone; Sulfonamides; Vasoconstrictor Agents | 1990 |
Central interactions between aldosterone and vasopressin on cardiovascular system.
Topics: Aldosterone; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Carbachol; Cardiovascular System; Drug Interactions; Heart Rate; Male; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Vasopressins | 1988 |
Modulation of angiotensin II binding sites in neuronal cultures by mineralocorticoids.
Topics: Aldosterone; Angiotensin II; Animals; Astrocytes; Brain Stem; Cells, Cultured; Corticosterone; Cycloheximide; Desoxycorticosterone; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Hypothalamus; Mineralocorticoids; Neurons; Progesterone; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Spironolactone; Testosterone | 1989 |
The apparent dependence of salt appetite in the pigeon on endogenous angiotensin II.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Appetite; Captopril; Columbidae; Drinking; Male; Receptors, Angiotensin; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium; Sodium Chloride; Spironolactone | 1987 |
Relative inhibitory potency of five mineralocorticoid antagonists on aldosterone biosynthesis in vitro.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Pregnenes; Ranidae; Spironolactone; Structure-Activity Relationship; Veratrum Alkaloids | 1985 |
Lack of renal effects of DOCA, ACTH, spironolactone, and angiotensin II in Squalus acanthias.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Animals; Desoxycorticosterone; Diuresis; Dogfish; Female; Glomerular Filtration Rate; Sharks; Spironolactone; Water-Electrolyte Balance | 1985 |
Salt appetite is suppressed by interference with angiotensin II and aldosterone.
Topics: Aldosterone; Angiotensin II; Animals; Appetite; Captopril; Cerebral Ventricles; Insulin; Male; Natriuresis; Rats; Rats, Inbred Strains; Sodium Chloride; Spironolactone | 1986 |
Corticosteroids decrease glomerular angiotensin receptors.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Animals; Hemodynamics; Kidney Glomerulus; Male; Natriuresis; Potassium; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sodium; Spironolactone | 1987 |
Sodium and the renin-angiotensin system in essential hypertension and mineralocorticoid excess.
Topics: Adolescent; Adult; Angiotensin II; Blood Pressure; Desoxycorticosterone; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mineralocorticoids; Renin; Sodium; Spironolactone | 1974 |
Renin in diabetes insipidus.
Topics: Angiotensin II; Diabetes Insipidus; Diuresis; Furosemide; Humans; Infusions, Parenteral; Renin; Spironolactone; Thiazines | 1965 |
[Bartter syndrome. Vascular angiotensin II resistance with juxtaglomerular cellular hyperplasia and hyperaldosteronism].
Topics: Adult; Angiotensin II; Humans; Hyperaldosteronism; Hyperplasia; Hypokalemia; Kidney Diseases; Potassium; Spironolactone | 1965 |
[Suppression by spirolactones of the natriuretic effect of angiotensin peculiar to certain cirrhotics].
Topics: Angiotensin II; Humans; Liver Cirrhosis; Natriuresis; Spironolactone | 1965 |
The specific cleavage of tyrosyl-peptide bonds by electrolytic oxidation.
Topics: Angiotensin II; Chemical Phenomena; Chemistry; Electrolysis; Glycine; Insulin; Ketones; Peptides; Spironolactone; Tyrosine | 1966 |
Normotensive secondary hyperaldosteronism.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Child, Preschool; Diet Therapy; Dwarfism; Female; Humans; Hyperaldosteronism; Hypokalemia; Juxtaglomerular Apparatus; Kidney Function Tests; Male; Norepinephrine; Potassium; Renin; Sodium; Spironolactone | 1966 |
Hypokalaemic alkalosis and hyperplasia of the juxtaglomerular apparatus without hypertension or oedema.
Topics: Adolescent; Alkalosis; Angiotensin II; Blood Pressure; Extracellular Space; Humans; Hyperaldosteronism; Hyperplasia; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Male; Potassium; Renin; Sodium; Spironolactone | 1967 |
Effects of furosemide uring antidiuresis and antinatriuresis induced by angiotensin.
Topics: Angiotensin II; Diuresis; Furosemide; Glomerular Filtration Rate; Humans; Iodine Isotopes; Kidney; Liver Cirrhosis; Natriuresis; Potassium; Sodium; Spironolactone; Water-Electrolyte Balance | 1967 |
[The influence of aldosterone and aldosterone antagonists on the pressor effect of synthetic Angiotensin II in primary chronic adrenal cortex insufficiency (M. Addison)].
Topics: Addison Disease; Adult; Aldosterone; Angiotensin II; Blood Pressure; Glucocorticoids; Humans; Male; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Progesterone; Spironolactone; Vasomotor System | 1966 |
Hyperplasia of the juxtaglomerular complex with secondary aldosteronism without hypertension (Bartter's syndrome).
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Ammonium Chloride; Angiotensin II; Bicarbonates; Body Height; Body Weight; Catecholamines; Child; Chlorides; Diet; Female; Glucose Tolerance Test; Humans; Hyperaldosteronism; Hyperplasia; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Function Tests; Metyrapone; Microscopy, Electron; Muscles; Norepinephrine; Pituitary-Adrenal Function Tests; Potassium; Renin; Serum Albumin; Sodium; Spironolactone; Triamterene; Water-Electrolyte Balance | 1968 |
[Angiotensin and saluretics in nephrogenic diabetes insipidus of early infancy].
Topics: Angiotensin II; Body Temperature; Chlorthalidone; Diabetes Insipidus; Electrolytes; Female; Furosemide; Humans; Hydrochlorothiazide; Hypernatremia; Infant, Newborn; Kidney; Kidney Tubules; Sodium; Spironolactone; Sweat | 1967 |
Activation of aldosterone secretion in primary aldosteronism.
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Glucocorticoids; Humans; Hyperaldosteronism; Pituitary-Adrenal Function Tests; Renin; Spironolactone | 1969 |
[Differential diagnosis of the Bartter syndrome].
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Biopsy; Chymosin; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Hypokalemia; Kidney; Sodium; Spironolactone | 1968 |
Medical grand rounds from the University of Alabama Medical Center.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Renin; Spironolactone | 1969 |
[Inhibition of natriuretic effect of angiotensin by spirolactones and salidiuretics in cirrhosis and arterial hypertension].
Topics: Angiotensin II; Chlorthalidone; Creatinine; Depression, Chemical; Diet, Sodium-Restricted; Glomerular Filtration Rate; Humans; Hypertension; Inulin; Kidney Tubules; Liver Cirrhosis; Natriuresis; Norepinephrine; Potassium; Spironolactone; Water | 1969 |
Effect of aldosterone on angiotensin-induced glycosuria.
Topics: Aldosterone; Angiotensin II; Animals; Glycosuria; Hyperglycemia; Injections, Intravenous; Rabbits; Renin; Spironolactone; Time Factors; Urine | 1969 |
Mechanism of angiotensin-induce glycosuria.
Topics: Aldosterone; Angiotensin II; Animals; Blood Glucose; Epinephrine; Glycosuria; Hyperglycemia; Injections, Intravenous; Mouth; Rabbits; Spironolactone; Time Factors; Urine | 1969 |
Pathogenesis of Bartter's syndrome.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Albumins; Aldosterone; Alkalosis; Angiotensin II; Aniline Compounds; Anticonvulsants; Child; Dexamethasone; Female; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney; Norepinephrine; Potassium; Potassium Chloride; Pyridones; Renin; Secretory Rate; Sodium; Spironolactone | 1969 |
Suppressed plasma renin activity in essential hypertension. Roles of plasma volume, blood pressure, and sympathetic nervous system.
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Catecholamines; Diet; Epinephrine; Extracellular Space; Female; Guanethidine; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Posture; Potassium; Renin; Sodium; Spironolactone; Sympathetic Nervous System | 1970 |
[Chronic idiopathic hypokalemia with hyperkaliuria in a very young infant. (Bioclinical and histological study)].
Topics: Aldosterone; Alkalosis; Angiotensin II; Calcium; Chlorides; Diet, Sodium-Restricted; Growth Disorders; Humans; Hypokalemia; Infant; Kidney; Kidney Function Tests; Lipids; Male; Potassium; Potassium Chloride; Sodium; Spironolactone | 1969 |
Interrelationships of renin and aldosterone in a patient with hypoaldosteronism.
Topics: Adrenal Insufficiency; Aged; Aldosterone; Angiotensin II; Diet; Diet, Sodium-Restricted; Female; Humans; Renin; Sodium Chloride; Spironolactone | 1970 |
Bartter's syndrome. A report of four cases, including three in one sibship, with comparative histologic evaluation of the juxtaglomerular apparatuses and glomeruli.
Topics: Alkalosis; Angiotensin II; Blood Pressure; Carbon Dioxide; Cerebrospinal Fluid Proteins; Electrolytes; Female; Glycosuria; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Infant; Infant, Newborn; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Glomerulus; Magnesium; Male; Microscopy; Microscopy, Electron; Phosphorus; Proteinuria; Specific Gravity; Spironolactone | 1970 |
An unusual type of hypokalaemic alkalosis with a disturbance of renin and aldosterone.
Topics: Adolescent; Adrenal Cortex Hormones; Albumins; Aldosterone; Alkalosis; Angiotensin II; Creatinine; Diet, Sodium-Restricted; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Kidney Diseases; Male; Potassium; Renin; Spironolactone; Triamterene | 1970 |
Case studies of siblings with juxtaglomerular hyperplasia and secondary aldosteronism associated with severe azotemia and renal rickets--Bartter's syndrome or disease?
Topics: Aldosterone; Alkalosis; Angiotensin II; Bone Diseases; Child; Child, Preschool; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Kidney Glomerulus; Male; Spironolactone; Triamterene; Valine | 1970 |
Neurodegenerative disorders and hyperaldosteronism.
Topics: Adolescent; Aldosterone; Angiotensin II; Birth Weight; Blood Pressure; Body Weight; Bundle-Branch Block; Central Nervous System Diseases; Cerebrospinal Fluid Proteins; Child; Electrocardiography; Electroencephalography; Electromyography; Eye Diseases; Female; Humans; Hyperaldosteronism; Intelligence; Leukoencephalitis, Acute Hemorrhagic; Magnesium; Male; Nerve Degeneration; Potassium; Retinal Diseases; Retinal Pigments; Sodium; Spironolactone | 1971 |
[The effect of alpha methyldopa and spironolactone on angiotensin sensitivity in man].
Topics: Adult; Angiotensin II; Blood Pressure; Depression, Chemical; Drug Synergism; Female; Humans; Hypertension; Male; Methyldopa; Middle Aged; Renin; Spironolactone; Stimulation, Chemical | 1972 |
[The renin-angiotensin-aldosterone system. Disorders and methods of clinical research].
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Aldosterone; Angiotensin II; Dexamethasone; Electrolytes; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Methods; Mineralocorticoids; Pituitary-Adrenal Function Tests; Radioimmunoassay; Renin; Spironolactone | 1970 |
[Urinary excretion of aldosterone in experimental saturnism].
Topics: Aldosterone; Angiotensin II; Animals; Lead Poisoning; Rabbits; Renin; Spironolactone | 1971 |
Drug modification of digital vascular reactivity to vasoactive substances.
Topics: Aldosterone; Angiotensin II; Benzothiadiazines; Blood Pressure; Dihydroxyphenylalanine; Fingers; Guanethidine; Humans; Hypertension; Hypertension, Renal; Norepinephrine; Prednisone; Raynaud Disease; Regional Blood Flow; Sodium Chloride; Spironolactone; Tyramine; Vasoconstrictor Agents; Vasodilator Agents | 1969 |
Comparison of surgery and prolonged spironolactone therapy in patients with hypertension, aldosterone excess, and low plasma renin.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Blood Volume; Body Weight; Extracellular Space; Female; Humans; Hyperaldosteronism; Hypertension; Male; Middle Aged; Postoperative Care; Potassium; Renin; Sodium; Spironolactone; Urea | 1972 |
Low renin hypertension and the adrenal cortex.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Blood Pressure; Corticosterone; Desoxycorticosterone; Diuresis; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hypertension; Hypokalemia; Indoles; Male; Pyridines; Renin; Secretory Rate; Spironolactone; Sulfonic Acids | 1972 |
[Physiopathologic bases of diagnosis and treatment of primary hyperaldosteronism].
Topics: Aged; Angiotensin II; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone | 1970 |
Stimulation of aldosterone production in vitro and its inhibition by spironolactone.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Butyrates; Chromatography, Gas; Chromatography, Thin Layer; Cyclic AMP; Esters; In Vitro Techniques; Lactones; Male; Mineralocorticoid Receptor Antagonists; Oxidation-Reduction; Potassium; Rats; Rats, Inbred Strains; Spironolactone | 1972 |
[Plasma aldosterone levels in primary aldosteronism. 1. Renin-angiotensin system and aldosterone].
Topics: Aldosterone; Angiotensin II; Enzyme Activation; Furosemide; Humans; Hydrochlorothiazide; Hyperaldosteronism; Posture; Renin; Spironolactone | 1973 |
Six year follow-up of a child with Bartter syndrome.
Topics: Aldosterone; Alkalosis; Angiotensin II; Biopsy; Blood Pressure; Child, Preschool; Diet Therapy; Female; Follow-Up Studies; Growth Disorders; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney Concentrating Ability; Kidney Diseases; Norepinephrine; Potassium; Renin; Secretory Rate; Sodium Chloride; Spironolactone; Syndrome; Vasopressins | 1973 |
Some observations on the pathogenesis of Bartter's syndrome.
Topics: Adult; Aldosterone; Alkalosis; Angiotensin II; Blood Volume; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hyperplasia; Hypertrophy; Hypokalemia; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Male; Potassium; Propranolol; Renin; Spironolactone | 1973 |
Editorial: New knowledge of benign essential hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Ethnicity; Humans; Hypertension; Propranolol; Renin; Spironolactone | 1973 |
Spironolactone and amiloride in the treatment of low renin hyperaldosteronism and related syndromes.
Topics: Adrenocortical Hyperfunction; Amiloride; Angiotensin II; Body Water; Corticosterone; Diuretics; Extracellular Space; Humans; Hyperaldosteronism; Hypertension; Plasma Volume; Potassium; Pyrazines; Renin; Secretory Rate; Sodium; Spironolactone; Urea | 1973 |
Angiotensin-salt hypertension.
Topics: Angiotensin II; Animals; Body Fluids; Body Weight; Diet, Sodium-Restricted; Hypertension; Kidney Medulla; Rats; Sodium Chloride; Spironolactone; Transplantation, Homologous | 1973 |
[How to advance antihypertensive therapy].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Humans; Hypertension; Methyldopa; Middle Aged; Mineralocorticoid Receptor Antagonists; Prostaglandins; Renin; Spironolactone; Time Factors | 1974 |
Regulation of aldosterone in the syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Topics: Adrenocorticotropic Hormone; Adult; Aged; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Hormones, Ectopic; Humans; Hydrocortisone; Male; Middle Aged; Natriuresis; Potassium; Radioimmunoassay; Renin; Sodium; Spironolactone; Syndrome; Vasopressins; Water Deprivation | 1974 |
Effect of alpha-methyldopa and of spironolactone on angiotensin responsiveness in man.
Topics: Angiotensin II; Blood Pressure; Humans; Methyldopa; Renin; Spironolactone | 1972 |
Renin-angiotensin-aldosterone system of a woman with Bartter's syndrome: Juxtaglomerular cell hyperplasia without hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Hypokalemia; Juxtaglomerular Apparatus; Kidney Diseases; Potassium; Potassium Chloride; Radioisotope Renography; Renin; Sodium; Sodium Chloride; Spironolactone; Syndrome | 1974 |
The renin-angiotensin system of uninephrectomized rats under diuretic treatment.
Topics: Angiotensin II; Animals; Blood Pressure; Diuretics; Furosemide; Glomerular Filtration Rate; Kidney; Male; Nephrectomy; Rats; Renin; Spironolactone; Triamterene | 1974 |
The role of mineralocorticoids in the pathogenesis of hypokalemic periodic paralysis.
Topics: Adult; Aldosterone; Angiotensin II; Desoxycorticosterone; Humans; Hydrocortisone; Hyperaldosteronism; Hypokalemia; Male; Metyrapone; Mineralocorticoids; Paralysis; Periodicity; Sodium; Spironolactone | 1974 |
Characteristics of hypertension in the black population.
Topics: Adult; Angiotensin II; Animals; Black or African American; Cardiomegaly; Cerebrovascular Disorders; Chlorthalidone; Coronary Disease; Drug Therapy, Combination; Female; Guanethidine; Heart Ventricles; Humans; Hydralazine; Hypertension; Male; Methyldopa; Middle Aged; New York City; Rabbits; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
Adolescent hypertension. II. Characteristics and response to treatment.
Topics: Adolescent; Adult; Angiotensin II; Black or African American; Female; Humans; Hydralazine; Hypertension; Kidney; Latin America; Male; Mass Screening; Methyldopa; New York City; Propranolol; Radioimmunoassay; Renin; Sodium; Spironolactone | 1974 |
Stimulation of angiotensinogen release by hemodilution in the dog.
Topics: Angiotensin II; Animals; Blood Proteins; Dextrans; Dogs; Exchange Transfusion, Whole Blood; Glucocorticoids; Male; Renin; Spironolactone | 1974 |
Pseudohypoaldosteronism: persistence of hyperaldosteronism and evidence for renal tubular and intestinal responsiveness to endogenous aldosterone.
Topics: Aldosterone; Angiotensin II; Child; Colon; Creatinine; Feces; Humans; Hydrocortisone; Hyperaldosteronism; Intestinal Mucosa; Kidney Function Tests; Kidney Tubules; Male; Potassium; Radioimmunoassay; Renin; Sodium; Spironolactone; Tritium | 1974 |
[Letter: Effect of diuretics in diabetes insipidus].
Topics: Angiotensin II; Benzothiadiazines; Diabetes Insipidus; Diuresis; Diuretics; Ethacrynic Acid; Furosemide; Humans; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1974 |
In vitro responses of aldosterone-producing adenomas to angiotensin II and ACTH after treatment with spironolactone before adrenalectomy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Combined Modality Therapy; Humans; Hyperaldosteronism; In Vitro Techniques; Potassium; Spironolactone; Time Factors | 1984 |
Effect of spironolactone administration on plasma and urinary aldosterone in man and the rat.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Humans; Hydrocortisone; Male; Rats; Renin; Species Specificity; Spironolactone | 1980 |
Normotensive primary aldosteronism: report of a case.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Angiotensin II; Angiotensin III; Blood Pressure; Dexamethasone; Electrolytes; Humans; Hyperaldosteronism; Male; Norepinephrine; Radionuclide Imaging; Renin; Spironolactone | 1981 |
Effect of aldosterone antagonists on mineralocorticoid synthesis in vitro. Inhibition of aldosterone production by prorenoate-K.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; In Vitro Techniques; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal Function Tests; Rana ridibunda; Spironolactone | 1982 |
[Direct action of mineralocorticoid antagonists on biosynthesis of aldosterone: comparative activities of several new compounds].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Pregnenes; Ranidae; Receptors, Mineralocorticoid; Receptors, Steroid; Spironolactone; Veratrum Alkaloids | 1983 |
Aldosterone escape to chronic ACTH administration in man.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Angiotensin II; Diet, Sodium-Restricted; Humans; Hydrocortisone; Male; Renin; Renin-Angiotensin System; Sodium; Spironolactone; Triamterene | 1983 |
The effect of the antimineralocorticoid RU 28318 on aldosterone biosynthesis in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Kinetics; Rana ridibunda; Spironolactone; Time Factors | 1984 |
Role of adrenal steroids on electroacupuncture analgesia and on antagonising potency of naloxone.
Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Angiotensin II; Animals; Captopril; Desoxycorticosterone; Dexamethasone; Electric Stimulation Therapy; Male; Mineralocorticoids; Naloxone; Rats; Spironolactone; Time Factors; Transcutaneous Electric Nerve Stimulation | 1984 |
Metabolic effects of high dose amiloride and spironolactone: a comparative study in normal subjects.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Dose-Response Relationship, Drug; Endocrine Glands; Humans; Male; Metabolism; Mineralocorticoids; Potassium; Pyrazines; Renin; Sodium; Spironolactone; Time Factors | 1984 |
Relation of rates of excretion of urinary prostaglandin E metabolites to administration of angiotensin, aldosterone, and spironolactone in vivo.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Animals; Hypertension; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Spironolactone | 1984 |
Characterization of a group of essential hypertensives with impaired regulation of aldosterone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Angiotensin II; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Potassium; Renin; Sodium; Spironolactone | 1982 |
Angiotensin II, plasma renin and sodium depletion as determinants of blood pressure response to saralasin in essential hypertension.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hypertension; Hyponatremia; Infusions, Parenteral; Male; Metolazone; Middle Aged; Renin; Saralasin; Sodium; Spironolactone | 1980 |
Bartter's syndrome: effect of indomethacin on prostaglandins, urinary kallikrein, renin-angiotensin-aldosterone system, and the response to angiotensin II antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Aldosterone; Aminoglutethimide; Angiotensin II; Aspirin; Bartter Syndrome; Blood Pressure; Diet, Sodium-Restricted; Female; Humans; Hyperaldosteronism; Indomethacin; Kallikreins; Male; Middle Aged; Prostaglandins E; Renin; Spironolactone | 1980 |
Combined captopril and spironolactone treatment in Conn's syndrome with renal impairment and refractory hypertension.
Topics: Adult; Angiotensin II; Captopril; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hypertension; Kidney Failure, Chronic; Male; Proline; Sodium; Spironolactone | 1981 |
Role of angiotensin-II in the polydipsia of diabetes insipidus in the Brattleboro rat.
Topics: Angiotensin II; Animals; Captopril; Diabetes Insipidus; Drinking; Furosemide; Male; Quinine; Rats; Rats, Inbred Strains; Spironolactone | 1981 |
Effect of indomethacin in two siblings with a renin-dependent hypertension, hyperaldosteronism and hypokalemia.
Topics: Adolescent; Adult; Angiotensin II; Drug Therapy, Combination; Female; Humans; Hyperaldosteronism; Hypertension; Hypokalemia; Indomethacin; Male; Propranolol; Prostaglandins; Renin; Saralasin; Spironolactone; Syndrome | 1980 |
Amiloride, spironolactone, and potassium chloride in thiazide-treated hypertensive patients.
Topics: Adult; Aldosterone; Amiloride; Angiotensin II; Bendroflumethiazide; Bicarbonates; Blood Pressure; Diuretics; Female; Humans; Hypertension; Hypokalemia; Male; Middle Aged; Placebos; Potassium; Potassium Chloride; Pyrazines; Sodium; Sodium Chloride Symporter Inhibitors; Spironolactone | 1980 |
Left ventricular fibrosis in renovascular hypertensive rats. Effect of losartan and spironolactone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biochemical Phenomena; Biochemistry; Biphenyl Compounds; Cardiomyopathies; Collagen; Endomyocardial Fibrosis; Fibrosis; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Microscopy, Polarization; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Spironolactone; Tetrazoles | 1995 |
Aldosterone regulation in primary aldosteronism.
Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Humans; Hyperaldosteronism; Spironolactone | 1994 |
Hypertension induced by a nonpressor dose of angiotensin II in kininogen-deficient rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Kininogens; Kinins; Male; Molecular Weight; Rats; Sodium; Spironolactone | 1994 |
Angiotensin II associated cardiac myocyte necrosis: role of adrenal catecholamines.
Topics: Adrenal Medulla; Adrenalectomy; Angiotensin II; Animals; Catecholamines; Cell Death; Fibronectins; Heart; Male; Microscopy, Fluorescence; Myocardium; Rats; Rats, Sprague-Dawley; Spironolactone | 1994 |
Antifibrotic effects of spironolactone in preventing myocardial fibrosis in systemic arterial hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Cardiomyopathies; Fibrosis; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Spironolactone | 1993 |
Independence of salt intake induced by calcium deprivation from the renin-angiotensin-aldosterone system.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Calcium; Diet; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Sodium; Sodium Chloride; Sodium, Dietary; Spironolactone | 1993 |
Role of aldosterone in the remnant kidney model in the rat.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Disease Models, Animal; Enalapril; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Mineralocorticoid Receptor Antagonists; Nephrectomy; Organ Size; Rats; Rats, Sprague-Dawley; Spironolactone; Tetrazoles | 1996 |
Long-term follow-up of a girl with the neonatal form of Bartter's syndrome.
Topics: Angiotensin I; Angiotensin II; Bartter Syndrome; Female; Follow-Up Studies; Growth; Humans; Indomethacin; Infant; Potassium; Spironolactone | 1997 |
Aldosterone mediates angiotensin II-stimulated rat vascular smooth muscle cell proliferation.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Cell Division; Cells, Cultured; Cytochrome P-450 CYP11B2; Drug Synergism; Losartan; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spironolactone; Stimulation, Chemical | 2000 |
Different regulation of cardiac and renal corticosteroid receptors in aldosterone-salt treated rats: effect of hypertension and glucocorticoids.
Topics: Adrenalectomy; Age Factors; Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blotting, Western; Collagen; Glucocorticoids; Heart; Hypertension; Kidney; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Steroid; RNA, Complementary; Sodium Chloride; Spironolactone; Time Factors | 2000 |
Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blotting, Northern; Creatinine; Disease Progression; Fibrosis; Gene Expression; Glomerulosclerosis, Focal Segmental; In Situ Hybridization; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone | 2000 |
Aldosterone: a mediator of myocardial necrosis and renal arteriopathy.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Blood Pressure; Cardiomyopathies; Enzyme Inhibitors; Eplerenone; Hormone Antagonists; Kidney; Male; Myocardium; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Renal Artery; Renin; Sodium Chloride; Spironolactone; Vascular Diseases | 2000 |
Cardiac aldosterone production in genetically hypertensive rats.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Corticosterone; Cytochrome P-450 CYP11B2; Heart Ventricles; Hypertension; In Vitro Techniques; Mineralocorticoid Receptor Antagonists; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; RNA, Messenger; Spironolactone | 2000 |
Acid-base and endocrine effects of aldosterone and angiotensin II inhibition in metabolic acidosis in human patients.
Topics: Acid-Base Equilibrium; Acidosis; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Chronic Disease; Electrolytes; Female; Humans; Hydrocortisone; Losartan; Male; Nitrogen; Spironolactone | 2000 |
Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Cardiovascular Diseases; Fibroblast Growth Factor 2; Heart; Immunohistochemistry; Mineralocorticoid Receptor Antagonists; NF-kappa B; Organ Size; Platelet-Derived Growth Factor; Rats; Receptors, Mineralocorticoid; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tetrazoles; Transcription Factor AP-1; Transforming Growth Factor beta; Valine; Valsartan | 2001 |
Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Calibration; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Heart Ventricles; Lung; Mineralocorticoid Receptor Antagonists; Myocardium; Peptidyl-Dipeptidase A; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Up-Regulation | 2001 |
Treatment of heart failure: state of the art and prospectives.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cardiomegaly; Drug Therapy; Endothelins; Heart Failure; Humans; Norepinephrine; Review Literature as Topic; Spironolactone; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left | 2001 |
Cardiac damage prevention by eplerenone: comparison with low sodium diet or potassium loading.
Topics: Aldosterone; Angiotensin II; Animals; Diet, Sodium-Restricted; Disease Models, Animal; Eplerenone; Heart Diseases; Male; Mineralocorticoid Receptor Antagonists; NG-Nitroarginine Methyl Ester; Potassium; Rats; Rats, Wistar; Spironolactone | 2002 |
[Aldosterone blockade in heart failure. So much for so little].
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Clinical Trials as Topic; Coronary Circulation; Diuretics; Heart Failure; Hemodynamics; Humans; Microcirculation; Mineralocorticoid Receptor Antagonists; Placebos; Rats; Rats, Inbred WKY; Spironolactone | 2002 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertension; Imidazoles; Male; Natriuretic Peptide, Brain; Prodrugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Spironolactone; Stroke; Tetrazoles; Time Factors | 2002 |
Spironolactone improves angiotensin-induced vascular changes and oxidative stress.
Topics: Aldosterone; Angiotensin II; Animals; Arteries; Blood Pressure; Culture Techniques; Endothelium, Vascular; Heart; Male; Mesenteric Arteries; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin; Spironolactone; Superoxides; Thiobarbituric Acid Reactive Substances; Vascular Resistance | 2002 |
Selective aldosterone blockade prevents angiotensin II/salt-induced vascular inflammation in the rat heart.
Topics: Adrenalectomy; Aldosterone; Angiotensin II; Animals; Body Weight; Coronary Disease; Coronary Vessels; Corticosterone; Cyclooxygenase 2; Diuresis; Drinking; Eating; Eplerenone; Heart; Hypertension; Isoenzymes; Macrophages; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Necrosis; Organ Size; Osteopontin; Potassium; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Renin; Sialoglycoproteins; Sodium; Sodium Chloride; Spironolactone; Vasculitis | 2002 |
Resistance artery mechanics and composition in angiotensin II-infused rats: effects of aldosterone antagonism.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Collagen; Hydralazine; Male; Mesenteric Arteries; Microscopy, Confocal; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Renin; Spironolactone; Vascular Resistance; Vasodilator Agents | 2003 |
Long-term regulation of ENaC expression in kidney by angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzothiadiazines; Bicarbonates; Biphenyl Compounds; Diuretics; Epithelial Sodium Channels; Gene Expression Regulation; Immunoblotting; Infusion Pumps; Injections, Subcutaneous; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Distal; Male; Mineralocorticoid Receptor Antagonists; Potassium; Protein Subunits; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Channels; Sodium Chloride Symporter Inhibitors; Sodium Chloride Symporters; Sodium Chloride, Dietary; Spironolactone; Symporters; Tetrazoles; Time Factors | 2003 |
[DIURETIC THERAPY OF THE ASCITIC FORM OF LIVER CIRRHOSIS WITH ANGIOTENSIN II AND THE MECHANISM OF ITS ACTION].
Topics: Angiotensin II; Angiotensins; Ascites; Diuresis; Diuretics; Drug Therapy; Humans; Kidney Glomerulus; Liver Cirrhosis; Spironolactone | 1964 |
Aldosterone and not plasminogen activator inhibitor-1 is a critical mediator of early angiotensin II/NG-nitro-L-arginine methyl ester-induced myocardial injury.
Topics: Aldosterone; Angiotensin II; Animals; Cardiovascular Diseases; Coronary Artery Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Myocardium; NG-Nitroarginine Methyl Ester; Plasminogen Activator Inhibitor 1; Proteinuria; Sodium, Dietary; Spironolactone | 2003 |
Distinct responses of membranoproliferative glomerulonephritis-related proteinuria to spironolactone with and without angiotensin II blockade.
Topics: Angiotensin II; Diuretics; Glomerulonephritis, Membranoproliferative; Humans; Proteinuria; Spironolactone | 2003 |
Aldosterone antagonist facilitates the cardioprotective effects of angiotensin receptor blockers in hypertensive rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Cardiomegaly; Cardiotonic Agents; Collagen Type I; Collagen Type III; Drug Synergism; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Spironolactone; Tetrazoles | 2004 |
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Diseases; Apolipoproteins E; Arteriosclerosis; Cell Line; Enzyme Induction; Eplerenone; Hormone Antagonists; Humans; Lipid Peroxidation; Lipoproteins, LDL; Losartan; Macrophages, Peritoneal; Membrane Proteins; Mice; Mice, Knockout; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Phosphoproteins; Protein Transport; Ramipril; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; RNA, Messenger; Spironolactone; Superoxides | 2004 |
Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Apoptosis; Blood Pressure; Cardiomegaly; Cell Size; Eplerenone; Fibrosis; Heart Rate; Hypertrophy, Left Ventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; Osteopontin; Reverse Transcriptase Polymerase Chain Reaction; Sialoglycoproteins; Spironolactone; Ultrasonography; Ventricular Remodeling | 2004 |
Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Cells, Cultured; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Male; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spironolactone | 2004 |
Aldosterone does not mediate angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.
Topics: Aldosterone; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol; Diuretics; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mineralocorticoid Receptor Antagonists; Organ Size; Spironolactone | 2005 |
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adenoviridae; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aorta; Cell Line, Transformed; Coronary Vessels; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; Humans; Hydrocortisone; Losartan; Mammary Tumor Virus, Mouse; Models, Biological; Muscle, Smooth, Vascular; Myocardial Ischemia; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Spironolactone; Transcription, Genetic; Transduction, Genetic | 2005 |
Genomic and nongenomic effects of aldosterone in the rat heart: why is spironolactone cardioprotective?
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Cardiotonic Agents; Cells, Cultured; Collagen; Coronary Circulation; DNA; Fibroblasts; Heart; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Spironolactone; Thymidine; Vasoconstrictor Agents; Ventricular Function, Left | 2005 |
Determinants of increased angiotensin II levels in severe chronic heart failure patients despite ACE inhibition.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Feedback, Physiological; Female; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Spironolactone | 2006 |
Role of aldosterone in angiotensin II-induced cardiac and aortic inflammation, fibrosis, and hypertrophy.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Collagen; Ectodysplasins; Fibrosis; Heart; Hypertension; Hypertrophy; Macrophages; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Myocarditis; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Spironolactone; Transcription Factor AP-1; Tumor Necrosis Factors; Vascular Cell Adhesion Molecule-1 | 2005 |
Mitigation of radiation nephropathy after internal alpha-particle irradiation of kidneys.
Topics: Actinium; Alpha Particles; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Urea Nitrogen; Captopril; Female; Imidazoles; Kidney; Kidney Tubules; Mice; Mice, Inbred BALB C; Mineralocorticoid Receptor Antagonists; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents; Random Allocation; Spironolactone; Tetrazoles | 2006 |
Effects of enalapril, tempol, and eplerenone on salt-induced hypertension in dahl salt-sensitive rats.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enalapril; Eplerenone; Epoprostenol; Hypertension; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Inbred Dahl; Sodium Chloride; Spin Labels; Spironolactone; Treatment Outcome | 2006 |
Urea transporter UT-A1 and aquaporin-2 proteins decrease in response to angiotensin II or norepinephrine-induced acute hypertension.
Topics: Acute Disease; Aldosterone; Angiotensin II; Animals; Aquaporin 2; Blood Pressure; Drinking; Hypertension, Renal; Male; Membrane Transport Proteins; Mineralocorticoid Receptor Antagonists; Norepinephrine; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1; Spironolactone; Thirst; Urea; Urea Transporters; Vasoconstrictor Agents; Water | 2006 |
Anti-inflammatory effect of spironolactone on human peripheral blood mononuclear cells.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Chemokine CCL2; Dose-Response Relationship, Drug; Female; Humans; Leukocytes, Mononuclear; Male; Mineralocorticoid Receptor Antagonists; Spironolactone; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker.
Topics: Aldosterone; Angiotensin II; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP11B2; Diastole; Eplerenone; Heart Failure; Heart Ventricles; Male; Mass Spectrometry; Mineralocorticoid Receptor Antagonists; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Steroids; Stroke Volume; Ventricular Function, Left | 2007 |
Combined effects of low-dose spironolactone and captopril therapy in a rat model of genetic hypertrophic cardiomyopathy.
Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Congenic; Atrial Natriuretic Factor; Blood Pressure; Captopril; Cardiomyopathy, Hypertrophic; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Echocardiography; Injections, Subcutaneous; Myocardium; Organ Size; Random Allocation; Rats; Rats, Inbred Strains; Spironolactone; Ventricular Function, Left; Weight Loss | 2006 |
Dual blockade of aldosterone and angiotensin II additively suppresses TGF-beta and NADPH oxidase in the hypertensive kidney.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; Drug Synergism; Eplerenone; Hypertension; Indoles; Kidney; Male; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Sodium-Potassium-Exchanging ATPase; Spironolactone; Superoxide Dismutase; Transforming Growth Factor beta | 2007 |
Aldosterone up-regulates production of plasminogen activator inhibitor-1 by renal mesangial cells.
Topics: Acetylcysteine; Aldosterone; Angiotensin II; Animals; Antibodies; Cells, Cultured; Dose-Response Relationship, Drug; Mesangial Cells; Neutralization Tests; Plasminogen Activator Inhibitor 1; Rats; Reactive Oxygen Species; RNA, Messenger; Spironolactone; Time Factors; Transforming Growth Factor beta1; Up-Regulation | 2007 |
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation.
Topics: Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Body Weight; Cytokines; Disease Models, Animal; Eplerenone; Female; Fibroblasts; Fibrosis; Hypertension; Immunohistochemistry; In Situ Hybridization; Inflammation Mediators; Intercellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred BALB C; Mineralocorticoid Receptor Antagonists; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; Spironolactone; Tenascin; Up-Regulation; Vasoconstrictor Agents | 2007 |
Cross-talk between aldosterone and angiotensin II in vascular smooth muscle cell senescence.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Male; Muscle, Smooth, Vascular; Oxidative Stress; Proto-Oncogene Proteins p21(ras); Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Renin-Angiotensin System; RNA, Small Interfering; Spironolactone; Tetrazoles; Tumor Suppressor Protein p53; Valine; Valsartan | 2007 |
Aldosterone receptor antagonism alleviates proteinuria, but not malignant hypertension, in Cyp1a1-Ren2 transgenic rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cytochrome P-450 CYP1A1; Hematocrit; Hypertension, Malignant; Kidney; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Organ Size; Proteinuria; Rats; Renin; Sodium; Spironolactone | 2007 |
Avoiding vicious circles: mineralocorticoid receptor antagonism prevents vascular oxidative stress early after myocardial infarction.
Topics: Aldosterone; Angiotensin II; Animals; Endothelium, Vascular; Eplerenone; Humans; Mice; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Oxidative Stress; Rats; Signal Transduction; Spironolactone | 2007 |
Paradoxical mineralocorticoid receptor activation and left ventricular diastolic dysfunction under high oxidative stress conditions.
Topics: Angiotensin II; Animals; Antioxidants; Cyclic N-Oxides; Diastole; Disease Models, Animal; Eplerenone; Male; Mineralocorticoid Receptor Antagonists; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spin Labels; Spironolactone; Vasoconstrictor Agents; Ventricular Dysfunction, Left | 2008 |
Eplerenone inhibits the intracrine and extracellular actions of angiotensin II on the inward calcium current in the failing heart. On the presence of an intracrine renin angiotensin aldosterone system.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium Signaling; Cardiomyopathies; Cricetinae; Eplerenone; Heart Failure; Mineralocorticoid Receptor Antagonists; Models, Cardiovascular; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin-Angiotensin System; Spironolactone | 2008 |
Aldosterone, but not angiotensin II, reduces angiotensin converting enzyme 2 gene expression levels in cultured neonatal rat cardiomyocytes.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Cells, Cultured; Down-Regulation; Eplerenone; Mineralocorticoid Receptor Antagonists; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Time Factors | 2008 |
Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt.
Topics: Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fibrosis; Heart Diseases; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Rats; Sodium Chloride, Dietary; Spironolactone | 2009 |
Aldosterone blockade by Spironolactone improves the hypertensive vascular hypertrophy and remodeling in angiotensin II overproducing transgenic mice.
Topics: Aldosterone; Angiotensin II; Animals; Female; Hyperplasia; Hypertension; Hypertrophy; Male; Mice; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; Osteopontin; Renin-Angiotensin System; Spironolactone; Tunica Intima | 2009 |
Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Base Sequence; Cell Line; DNA Primers; Doxorubicin; Gene Expression Regulation, Enzymologic; Glucuronidase; Kidney Diseases; Kidney Glomerulus; Male; Podocytes; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Spironolactone | 2009 |
Electrophysiological responses of sympathetic preganglionic neurons to ANG II and aldosterone.
Topics: Aldosterone; Anesthetics, Local; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autonomic Fibers, Preganglionic; Benzimidazoles; Biphenyl Compounds; Eplerenone; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Male; Mineralocorticoid Receptor Antagonists; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Spironolactone; Synaptic Transmission; Tetrazoles; Tetrodotoxin; Time Factors | 2009 |
Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Cerebral Arteries; Chemokine CCL2; Eplerenone; Female; Gene Expression; Hypertension, Renal; Immunohistochemistry; Intracranial Aneurysm; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Ovariectomy; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tyrosine | 2009 |
Aldosterone stimulates the proliferation of uterine leiomyoma cells.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cell Line, Tumor; Female; Gene Expression; Leiomyoma; Rats; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Spironolactone; Up-Regulation; Uterine Neoplasms | 2010 |
Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-"ouabain" pathway.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brain; Cardenolides; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fadrozole; Heart Rate; Hypothalamus; Imidazoles; Immunoglobulin Fab Fragments; Immunohistochemistry; Infusion Pumps, Implantable; Infusions, Parenteral; Infusions, Subcutaneous; Male; Mineralocorticoid Receptor Antagonists; Neural Pathways; Neurons; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Wistar; Renin-Angiotensin System; Saponins; Spironolactone; Subfornical Organ; Telemetry; Time Factors | 2010 |
Further studies on the effects of intracrine and extracellular angiotensin II on the regulation of heart cell volume. On the influence of aldosterone and spironolactone.
Topics: Aldosterone; Angiotensin II; Animals; Cell Size; Cells, Cultured; Cricetinae; Flow Cytometry; Membrane Transport Proteins; Myocytes, Cardiac; Spironolactone | 2010 |
Angiotensin II and aldosterone-induced neuronal damage in neurons through an astrocyte-dependent mechanism.
Topics: Aldosterone; Angiotensin II; Animals; Astrocytes; Cells, Cultured; DNA Damage; Eplerenone; Ganglia, Spinal; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Valine; Valsartan | 2011 |
Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.
Topics: 3T3-L1 Cells; Adipocytes; Aldosterone; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Corticosterone; Culture Media, Conditioned; Eplerenone; Fadrozole; Fibronectins; Hormone Antagonists; Mice; Mice, Inbred C57BL; Mifepristone; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Spironolactone | 2011 |
Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Topics: Actins; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cellular Senescence; Eplerenone; Genes, p16; Genes, p53; Hydralazine; Hypertension; Imidazoles; Kidney; Mice; Mice, Inbred C57BL; p21-Activated Kinases; Sirtuin 1; Sodium Chloride; Spironolactone; Tetrazoles | 2012 |
Endogenous aldosterone is involved in vascular calcification in rat.
Topics: Aldosterone; Alkaline Phosphatase; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Captopril; Cholecalciferol; Collagen; Fibrosis; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Nicotine; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Vascular Calcification | 2012 |
Angiotensin II- and salt-induced kidney injury through Rac1-mediated mineralocorticoid receptor activation.
Topics: Acute Kidney Injury; Adrenalectomy; Aldosterone; Analysis of Variance; Angiotensin II; Animals; Blotting, Western; Disease Models, Animal; Eplerenone; Immunohistochemistry; Male; Mice; Mice, Inbred Strains; rac1 GTP-Binding Protein; Random Allocation; Real-Time Polymerase Chain Reaction; Receptors, Mineralocorticoid; Signal Transduction; Sodium Chloride, Dietary; Spironolactone; Statistics, Nonparametric | 2012 |
Additive amelioration of oxidative stress and cardiac function by combined mineralocorticoid and angiotensin receptor blockers in postinfarct failing hearts.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cells, Cultured; Disease Models, Animal; Drug Therapy, Combination; Heart Failure; Hemodynamics; Imidazoles; Lipid Peroxidation; Male; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; NADPH Oxidases; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone; Tetrazoles; Ventricular Function, Left | 2012 |
Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cytochrome P-450 CYP1A1; Hydrochlorothiazide; Hypertension; Kidney Tubules, Distal; Losartan; Male; Microvessels; Natriuresis; Rats; Rats, Transgenic; Renin; Sodium Chloride Symporters; Spironolactone | 2012 |
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Biomarkers; Blood Pressure; Cytochrome P-450 CYP11B2; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Heart Diseases; Inflammation; Kidney Diseases; Kidney Glomerulus; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Myocardium; Receptors, Mineralocorticoid; Renin-Angiotensin System; Sodium Chloride, Dietary; Spironolactone; Time Factors; Vascular Diseases | 2012 |
Rapid, dynamic changes in glomerular permeability to macromolecules during systemic angiotensin II (ANG II) infusion in rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Ficoll; Glomerular Filtration Rate; Infusions, Intravenous; Kidney Glomerulus; Male; Mineralocorticoid Receptor Antagonists; Nimodipine; Permeability; Rats; Rats, Wistar; Spironolactone; Tetrazoles; Vasodilator Agents | 2012 |
Targeting activated mineralocorticoid receptor: Occam's razor revisited.
Topics: Aldosterone; Angiotensin II; Animals; Heart Diseases; Kidney Diseases; Mineralocorticoid Receptor Antagonists; Receptors, Mineralocorticoid; Spironolactone; Vascular Diseases | 2012 |
Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1.
Topics: Aldosterone; Amiloride; Angiotensin II; Animals; Blood Pressure; DNA Primers; Gene Expression Regulation; Glomerular Filtration Rate; Hyperaldosteronism; Mice; Mice, Inbred C57BL; Natriuresis; Polymerase Chain Reaction; Renin; Sodium-Potassium-Exchanging ATPase; Spironolactone; Transforming Growth Factor beta1; Urinalysis | 2013 |
Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Eplerenone; Glutamic Acid; Heart Rate; Hypertension; Infusions, Intravenous; Infusions, Intraventricular; Kynurenic Acid; Male; Mineralocorticoid Receptor Antagonists; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Glutamate; Receptors, Mineralocorticoid; Signal Transduction; Spironolactone; Tetrazoles | 2013 |
Role of brain corticosterone and aldosterone in central angiotensin II-induced hypertension.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Brain; Corticosterone; Cytochrome P-450 CYP11B2; Dose-Response Relationship, Drug; Eplerenone; Fadrozole; Heart Rate; Hypertension; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Spironolactone | 2013 |
[Effect of angiotensin II and aldosterone on the proliferation of cardiac fibroblasts in rats].
Topics: Aldosterone; Angiotensin II; Animals; Cell Proliferation; Collagen; Fibroblasts; Losartan; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone | 2013 |
Interplay between sodium and calcium regulatory hormones: a clinically relevant research field.
Topics: Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Parathyroid Hormone; Renin-Angiotensin System; Spironolactone | 2014 |
Oxidative DNA damage in kidneys and heart of hypertensive mice is prevented by blocking angiotensin II and aldosterone receptors.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Deoxyguanosine; DNA Damage; DNA Repair; Enzyme Activation; Eplerenone; Guanosine; Heart; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Spin Labels; Spironolactone; Tetrazoles | 2014 |
Cooperative Role of Mineralocorticoid Receptor and Caveolin-1 in Regulating the Vascular Response to Low Nitric Oxide-High Angiotensin II-Induced Cardiovascular Injury.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Cardiovascular System; Caveolin 1; Cyclic GMP; Eplerenone; Heart Injuries; Male; Mice; Mineralocorticoid Receptor Antagonists; Models, Molecular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nucleic Acid Conformation; Receptors, Mineralocorticoid; Renin-Angiotensin System; Signal Transduction; Spironolactone; Vasoconstriction; Vasodilation | 2015 |
Angiotensin and mineralocorticoid receptor antagonism attenuates cardiac oxidative stress in angiotensin II-infused rats.
Topics: Adrenal Glands; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Diseases; Hypertension; Lipid Peroxidation; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardium; Oxidative Stress; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction; Spironolactone; Time Factors; Tyrosine | 2015 |
Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.
Topics: Angiotensin II; Animals; Blood Volume; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Electrolytes; Furosemide; HEK293 Cells; Humans; Kidney Tubules, Distal; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mutation; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pseudohypoaldosteronism; Recombinant Proteins; Spironolactone; Water-Electrolyte Balance | 2017 |
Spironolactone suppresses aldosterone-induced Kv1.5 expression by attenuating mineralocorticoid receptor-Nox1/2/4-mediated ROS generation in neonatal rat atrial myocytes.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Heart Atria; Kv1.5 Potassium Channel; Myocytes, Cardiac; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; Pyrazoles; Pyrazolones; Pyridines; Pyridones; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Mineralocorticoid; Spironolactone | 2019 |
Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy.
Topics: Angiotensin II; Animals; Cardiomegaly; Fibrosis; Genetic Therapy; Glycogen Storage Disease Type IIb; Heart Failure; Humans; Mice; Ramipril; Reactive Oxygen Species; Spironolactone | 2023 |