Page last updated: 2024-08-22

angiotensin ii and sirolimus

angiotensin ii has been researched along with sirolimus in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (21.62)	18.2507
2000's	9 (24.32)	29.6817
2010's	10 (27.03)	24.3611
2020's	10 (27.03)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Giasson, E; Meloche, S	1
Izumo, S; Sadoshima, J	1
Djurhuus, JC; Golbaekdal, K; Nielsen, CB; Pedersen, EB	1
Komuro, I; Kudoh, S; Takano, H; Yamazaki, T; Yazaki, Y; Zou, Y	1
Giasson, E; Meloche, S; Servant, MJ	1
Earp, HS; Graves, LM; Li, X; Yu, H	1
Anand-Srivastava, MB; Ge, C	1
Marsh, JD; Ritchie, RH; Schiebinger, RJ	1
Brautigan, D; Everett, AD; Nairn, AC; Stoops, TD	1
Block, ER; Li, YD; Patel, JM	1
Ahonen, J; Finckenberg, P; Ganten, D; Inkinen, K; Louhelainen, M; Luft, F; Merasto, S; Mervaala, E; Müller, D; Vapaatalo, H	1
Daigle, C; Dao, HH; Girardot, D; Martens, FM; Moreau, P; Touyz, RM	1
Chester, AH; Hafizi, S; Proud, CG; Wang, X; Yacoub, MH	1
Chiu, T; Rozengurt, E; Santiskulvong, C	1
Block, ER; Lu, J; Patel, JM; Zhang, J	1
Kisfalvi, K; Rey, O; Rozengurt, E; Sinnett-Smith, J; Young, SH	1
Bieri, M; Farkas, A; Ligeti, N; Marti, HP; Meier, B; Mohacsi, P; Oroszlán, M	1
Brailoiu, E; Brailoiu, GC; Deliu, E; Motoc, D; Tica, AA	1
Jang, HJ; Kim, JA; Martinez-Lemus, LA; Sowers, JR	1
Golledge, J; Jose, RJ; Körner, H; Moran, CS; Moxon, JV; Norman, PE; Roomberg, A; Rush, C	1
Axelsson, J; Rippe, A; Rippe, B	1
Bae, SS; Ha, JM; Jin, SY; Kim, YW; Lee, HS; Shin, HK; Song, SH; Yun, SJ	1
Alfadda, AA; Gul, R; Luck, C; Lum-Naihe, K; Mahmood, A; Pulakat, L; Speth, RC	1
Cao, S; Fan, J; Li, H; Mao, H; Peng, X; Wang, Y; Xiong, L; Yu, X; Zhuang, S	1
Chen, S; Du, XL; Li, FF; Shang, XK	1
Betz, MJ; Beuschlein, F; Burkard, T; Cavelti-Weder, C; Donath, MY; Hall, MN; Hepprich, M; Kratschmar, DV; Meienberg, F; Odermatt, A; Reincke, M; Seelig, E; Swierczynska, MM; Trinh, B	1
Chen, W; Gao, G; Liu, J; Luo, H; Wang, C; Yan, M; Yang, P	1
Aoki, H; Fukumoto, Y; Furusho, A; Hashimoto, Y; Hayashi-Hori, M; Hirakata, S; Ito, S; Majima, R; Matsukuma, M; Nishida, N; Ohno-Urabe, S	1
Chen, JW; Jiang, Y; Liu, D; Murao, K; Sun, WP; Wang, LH; Xue, R; Zhang, GX	1
Chen, L; Geng, Q; Jiang, W; Li, N; Wang, B; Wang, W; Xiong, R	1
Gan, W; He, T; Li, S; Qu, G; Shi, H; Wen, X; Zhang, A; Zhao, Y	1
Baskaran, R; Chen, RJ; Day, CH; Ho, TJ; Huang, CY; Kuo, WW; Lin, JY; Lin, MY; Lin, YM; Padma, VV	1
Bai, HY; Gu, HB; Li, H; Shan, BS; Zhou, X	1
Hu, G; Huang, D; Li, G; Li, N; Li, PL; Ritter, JK; Yuan, X; Zou, Y	1
Han, C; Hu, L; Huang, R; Huang, Y; Li, J; Lin, H; Ooi, K; Qian, X; Ren, X; Xia, C; Zhang, S	1
Ali, Y; Gomez-Sanchez, CE; Gomez-Sanchez, EP	1

Trials

1 trial(s) available for angiotensin ii and sirolimus

Article	Year
Treatment of Primary Aldosteronism With mTORC1 Inhibitors. The Journal of clinical endocrinology and metabolism, 2019, 10-01, Volume: 104, Issue:10 Topics: Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Everolimus; Female; Hemodynamics; Humans; Hyperaldosteronism; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Pilot Projects; Proof of Concept Study; Renin; Sirolimus	2019

Article

Year

Treatment of Primary Aldosteronism With mTORC1 Inhibitors.

The Journal of clinical endocrinology and metabolism, 2019, 10-01, Volume: 104, Issue:10

Topics: Adult; Aldosterone; Angiotensin II; Animals; Blood Pressure; Everolimus; Female; Hemodynamics; Humans; Hyperaldosteronism; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, 129 Strain; Mice, Inbred BALB C; Mice, Inbred C57BL; Middle Aged; Pilot Projects; Proof of Concept Study; Renin; Sirolimus

2019

Other Studies

36 other study(ies) available for angiotensin ii and sirolimus

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells. The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine	1995
Rapamycin selectively inhibits angiotensin II-induced increase in protein synthesis in cardiac myocytes in vitro. Potential role of 70-kD S6 kinase in angiotensin II-induced cardiac hypertrophy. Circulation research, 1995, Volume: 77, Issue:6 Topics: Analysis of Variance; Angiotensin II; Animals; Anti-Bacterial Agents; Cardiomegaly; Cells, Cultured; Enzyme Activation; Genes, fos; Immunoblotting; Muscle Proteins; Myocardium; Phenotype; Phosphorylation; Polyenes; Precipitin Tests; Protein Biosynthesis; Protein Serine-Threonine Kinases; Radioimmunoassay; Rats; Sirolimus; Staining and Labeling	1995
Effects of rapamycin on renal hemodynamics, water and sodium excretion, and plasma levels of angiotensin II, aldosterone, atrial natriuretic peptide, and vasopressin in pigs. Transplantation, 1994, Dec-15, Volume: 58, Issue:11 Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Heart Rate; Hemodynamics; Immunosuppressive Agents; Kidney; Lithium; Natriuresis; Polyenes; Renal Circulation; Sirolimus; Swine; Vasopressins	1994
Activation of p70 S6 protein kinase is necessary for angiotensin II-induced hypertrophy in neonatal rat cardiac myocytes. FEBS letters, 1996, Feb-05, Volume: 379, Issue:3 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Cells, Cultured; Enzyme Activation; Gene Expression; Genes, fos; Immunosuppressive Agents; Myocardium; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus	1996
Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27 Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Growth Substances; Insulin; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Phosphorylation; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; Sirolimus; Substrate Specificity; Tetradecanoylphorbol Acetate; Thrombin	1996
Protein kinase C and protein kinase A inhibit calcium-dependent but not stress-dependent c-Jun N-terminal kinase activation in rat liver epithelial cells. The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23 Topics: 1-Methyl-3-isobutylxanthine; Androstadienes; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Epithelium; Humans; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver; Mitogen-Activated Protein Kinases; Models, Biological; Polyenes; Protein Kinases; Rats; Recombinant Proteins; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Thapsigargin; Wortmannin	1997
Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in AII-mediated enhanced expression of Gi proteins in vascular smooth muscle cells. Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2 Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dactinomycin; Embryo, Mammalian; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Transcription, Genetic; Wortmannin	1998
Bradykinin-stimulated protein synthesis by myocytes is dependent on the MAP kinase pathway and p70(S6K). The American journal of physiology, 1999, Volume: 276, Issue:4 Topics: Angiotensin II; Animals; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus	1999
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:1 Topics: Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Morpholines; Myocardium; Peptide Elongation Factor 2; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sirolimus	2001
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation. American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:4 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Angiotensin II; Animals; Anti-Bacterial Agents; Cell Division; Cells, Cultured; Endothelium; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Swine; Wortmannin	2002
Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. The American journal of pathology, 2003, Volume: 163, Issue:1 Topics: Angiotensin II; Animals; Blood Pressure; Calcineurin; Collagen Type I; Collagen Type III; Connective Tissue Growth Factor; Cyclosporine; Everolimus; Gene Expression Regulation; Heart; Humans; Immediate-Early Proteins; Immunosuppressive Agents; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Kidney; Male; Organisms, Genetically Modified; Rats; Rats, Sprague-Dawley; Renin; Sirolimus; Transforming Growth Factor beta; Transforming Growth Factor beta1	2003
Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo. BMC cardiovascular disorders, 2004, May-10, Volume: 4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Flavonoids; Irbesartan; Leucine; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Tetrazoles	2004
ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells. American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Angiotensin II; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Chromones; Coronary Vessels; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Humans; Immunosuppressive Agents; Morpholines; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin	2004
EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway. American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 288, Issue:2 Topics: Angiotensin II; Animals; Cell Line; Cell Proliferation; DNA; ErbB Receptors; Gene Silencing; Intestinal Mucosa; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Transcriptional Activation	2005
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells. Molecular and cellular biochemistry, 2005, Volume: 275, Issue:1-2 Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Swine	2005
Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway. Endocrinology, 2007, Volume: 148, Issue:7 Topics: Angiotensin II; Blotting, Western; Bombesin; Bradykinin; Calcium Signaling; Cell Line, Tumor; Dose-Response Relationship, Drug; Humans; Hydrolysis; Inositol 1,4,5-Trisphosphate; Insulin; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Microscopy, Fluorescence; Myristoylated Alanine-Rich C Kinase Substrate; Neurotensin; Pancreatic Neoplasms; Phosphatidylinositol 4,5-Diphosphate; Phosphorylation; Protein Kinases; Receptors, G-Protein-Coupled; Sirolimus; TOR Serine-Threonine Kinases; Vasopressins	2007
Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway. Transplant immunology, 2010, Volume: 23, Issue:3 Topics: Albumins; Angiotensin II; Cell Line; Down-Regulation; Drug Therapy, Combination; Endocytosis; Epithelial Cells; Everolimus; Humans; Immunosuppressive Agents; Kidney Tubules, Proximal; Losartan; Low Density Lipoprotein Receptor-Related Protein-2; Ramipril; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Signal Transduction; Sirolimus	2010
Intracellular angiotensin II activates rat myometrium. American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:3 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arsenicals; Autophagy; Brefeldin A; Calcium Signaling; Carbolines; Cells, Cultured; Egtazic Acid; Endocytosis; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Estrenes; Female; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Lysosomes; Macrocyclic Compounds; Macrolides; Models, Biological; Myometrium; NADP; Oxazoles; Piperazines; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ryanodine; Saralasin; Signal Transduction; Sirolimus; Type C Phospholipases; Uterus	2011
Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation. American journal of physiology. Endocrinology and metabolism, 2012, Jan-15, Volume: 302, Issue:2 Topics: Angiotensin II; Animals; Cattle; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Insulin; Insulin Receptor Substrate Proteins; Male; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Vasodilation	2012
Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes. Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:4 Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Movement; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Everolimus; Flow Cytometry; Infusion Pumps, Implantable; Infusions, Subcutaneous; Interferon-gamma; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Protein Kinase Inhibitors; Receptor, Macrophage Colony-Stimulating Factor; Receptors, CCR2; Sirolimus; TOR Serine-Threonine Kinases	2013
mTOR inhibition with temsirolimus causes acute increases in glomerular permeability, but inhibits the dynamic permeability actions of puromycin aminonucleoside. American journal of physiology. Renal physiology, 2015, May-15, Volume: 308, Issue:10 Topics: Angiotensin II; Animals; Cell Membrane Permeability; Cyclic N-Oxides; Glomerular Filtration Rate; Kidney Glomerulus; Male; Models, Animal; Puromycin Aminonucleoside; Rats; Rats, Wistar; Sirolimus; Spin Labels; Time Factors; TOR Serine-Threonine Kinases	2015
Platelet-derived growth factor regulates vascular smooth muscle phenotype via mammalian target of rapamycin complex 1. Biochemical and biophysical research communications, 2015, Aug-14, Volume: 464, Issue:1 Topics: Angiotensin II; Animals; Aorta; Carrier Proteins; Cell Movement; Cell Proliferation; HEK293 Cells; Humans; Intracellular Signaling Peptides and Proteins; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphoproteins; Platelet-Derived Growth Factor; Primary Cell Culture; Rapamycin-Insensitive Companion of mTOR Protein; Rats; Rats, Sprague-Dawley; Regulatory-Associated Protein of mTOR; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases	2015
Regulation of cardiac miR-208a, an inducer of obesity, by rapamycin and nebivolol. Obesity (Silver Spring, Md.), 2015, Volume: 23, Issue:11 Topics: Angiotensin II; Animals; Cells, Cultured; Gene Expression Regulation; Male; Mediator Complex; Mice; MicroRNAs; Myocytes, Cardiac; Nebivolol; Obesity; Rats; Rats, Zucker; Signal Transduction; Sirolimus; Weight Gain	2015
Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis. Autophagy, 2016, Volume: 12, Issue:9 Topics: Angiotensin II; Animals; Autophagy; Autophagy-Related Protein 5; Cell Cycle; Cell Cycle Checkpoints; Cell Division; Collagen Type I; Epithelial Cells; Fibrosis; G2 Phase; Gene Deletion; Humans; Kidney; Kidney Diseases; Kidney Tubules; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Signal Transduction; Sirolimus	2016
Rapamycin Treatment Attenuates Angiotensin II -induced Abdominal Aortic Aneurysm Formation via VSMC Phenotypic Modulation and Down-regulation of ERK1/2 Activity. Current medical science, 2018, Volume: 38, Issue:1 Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Cells, Cultured; Down-Regulation; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Sirolimus	2018
Rapamycin regulates the balance between cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling. International journal of molecular medicine, 2020, Volume: 45, Issue:1 Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Cell Line; Echocardiography; Endoplasmic Reticulum Stress; Fluorescent Antibody Technique; Heart Failure; Male; Myocytes, Cardiac; Rats; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases	2020
Therapeutic Effect of Rapamycin on Aortic Dissection in Mice. International journal of molecular sciences, 2020, May-08, Volume: 21, Issue:9 Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Cell Cycle Checkpoints; Cell Line; Disease Models, Animal; Gefitinib; Gene Expression Regulation; Gene Ontology; Gene Regulatory Networks; Male; Mice; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; STAT3 Transcription Factor; TOR Serine-Threonine Kinases	2020
Autophagy contributes to angiotensin II induced dysfunction of HUVECs. Clinical and experimental hypertension (New York, N.Y. : 1993), 2021, Jul-04, Volume: 43, Issue:5 Topics: Acetophenones; Adenine; Angiotensin II; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; Benzimidazoles; Biphenyl Compounds; Decanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxy Acids; Models, Biological; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Signal Transduction; Sirolimus; Tetrazoles; Time Factors	2021
STING protects against cardiac dysfunction and remodelling by blocking autophagy. Cell communication and signaling : CCS, 2021, 11-08, Volume: 19, Issue:1 Topics: Angiotensin II; Animals; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Heart Failure; Humans; Membrane Proteins; Mice; Myocytes, Cardiac; Protective Agents; Signal Transduction; Sirolimus	2021
Rapamycin attenuated podocyte apoptosis via upregulation of nestin in Ang II-induced podocyte injury. Molecular biology reports, 2022, Volume: 49, Issue:3 Topics: Angiotensin II; Animals; Apoptosis; Nestin; Podocytes; Sirolimus; Up-Regulation	2022
Low-dose rapamycin prevents Ang-II-induced toxicity in Leydig cells and testicular dysfunction in hypertensive SHR model. Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:9 Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Female; Humans; Hydroxysteroid Dehydrogenases; Hypertension; Leydig Cells; Male; NF-E2-Related Factor 2; Phosphatidylinositol 3-Kinases; Rats; Rats, Inbred SHR; Sirolimus; Superoxides	2022
AT2 Receptor Stimulation Inhibits Vascular Smooth Muscle Cell Senescence Induced by Angiotensin II and Hyperglycemia. American journal of hypertension, 2022, 10-03, Volume: 35, Issue:10 Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Cellular Senescence; Glucose; Hyperglycemia; Imidazoles; Male; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 2; Sirolimus; Sulfonamides; Superoxides; Thiophenes	2022
Renomedullary exosomes produce antihypertensive effects in reversible two-kidney one-clip renovascular hypertensive mice. Biochemical pharmacology, 2022, Volume: 204 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuretics; Exosomes; Hypertension; Kidney; Lipids; Male; Mice; Natriuretic Agents; Sirolimus	2022
Inhibition of cGAS in Paraventricular Nucleus Attenuates Hypertensive Heart Injury Via Regulating Microglial Autophagy. Molecular neurobiology, 2022, Volume: 59, Issue:11 Topics: Angiotensin II; Animals; Autophagy; DNA, Mitochondrial; Heart Diseases; Heart Injuries; Hypertension; Mice; Microglia; Nucleotidyltransferases; Paraventricular Hypothalamic Nucleus; Sirolimus	2022
Mammalian Target of Rapamycin Inhibition Decreases Angiotensin II-Induced Steroidogenesis in HAC15 Human Adrenocortical Carcinoma Cells. Endocrinology, 2022, 11-14, Volume: 164, Issue:1 Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Humans; Hydrocortisone; RNA, Guide, Kinetoplastida; Sirolimus; TOR Serine-Threonine Kinases	2022