Page last updated: 2024-08-22

angiotensin ii and pitavastatin

angiotensin ii has been researched along with pitavastatin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Hatta, T; Irie, H; Kameyama, H; Kusaba, T; Kuwahara, N; Matsubara, H; Narumiya, H; Sasaki, S; Takeda, K; Tamagaki, K1
Arimoto, T; Konta, T; Koyama, Y; Kubota, I; Niizeki, T; Shishido, T; Takahashi, H; Takeishi, Y1
Inoguchi, T; Kobayashi, K; Nakayama, M; Nawata, H; Sasaki, S; Sato, N; Sonoda, N; Tsubouchi, H; Yu, HY1
Ayajiki, K; Kashiwagi, A; Masada, M; Nishio, Y; Okamura, T; Shinozaki, K; Yoshida, Y1
Aihara, K; Akaike, M; Azuma, H; Ikeda, Y; Ise, T; Ishikawa, K; Iwase, T; Matsumoto, T; Sumitomo, Y; Yagi, S; Yoshida, S1
Fukumoto, Y; Rashid, M; Seto, M; Shimokawa, H; Tawara, S; Yano, K1
Aihara, K; Akaike, M; Ikeda, Y; Ishikawa, K; Iwase, T; Matsumoto, T; Sata, M; Soeki, T; Sumitomo-Ueda, Y; Yagi, S; Yoshida, S1
Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL1
Hu, W; Jiang, WB1
Egashira, K; Katsuki, S; Koga, JI; Matoba, T; Nakano, K; Nakashiro, S; Tsutsui, H; Umezu, R1

Trials

2 trial(s) available for angiotensin ii and pitavastatin

ArticleYear
Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Angiotensin II; Animals; Atorvastatin; Cells, Cultured; Cross-Over Studies; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Leukocytes; Male; Pravastatin; Pyrroles; Quinolines; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction

2009
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection

2013

Other Studies

8 other study(ies) available for angiotensin ii and pitavastatin

ArticleYear
HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells.
    Cardiovascular research, 2004, Nov-01, Volume: 64, Issue:2

    Topics: Amides; Analysis of Variance; Angiotensin II; Atorvastatin; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Glucuronidase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Tubules; Klotho Proteins; Membrane Proteins; Pyridines; Pyrroles; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; rhoA GTP-Binding Protein; RNA, Messenger

2004
Pitavastatin inhibits cardiac hypertrophy in a rat model of progressive renal injury.
    Journal of cardiovascular pharmacology, 2005, Volume: 46, Issue:4

    Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Kidney; Male; Myocytes, Cardiac; Nephrectomy; Phosphorylation; Quinolines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents

2005
Statin attenuates high glucose-induced and angiotensin II-induced MAP kinase activity through inhibition of NAD(P)H oxidase activity in cultured mesangial cells.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:5

    Topics: Angiotensin II; Cells, Cultured; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Glucose; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mesangial Cells; Mitogen-Activated Protein Kinases; NADPH Oxidases; Naphthalenes; Onium Compounds; Oxidative Stress; Quinolines; Sensitivity and Specificity; Structure-Activity Relationship

2005
Pitavastatin restores vascular dysfunction in insulin-resistant state by inhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxide synthase-dependent superoxide production.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:3

    Topics: Angiotensin II; Animals; Aorta; Blotting, Western; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation; GTP Cyclohydrolase; Insulin Resistance; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Quinolines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Superoxides

2007
Pitavastatin, an HMG-CoA reductase inhibitor, exerts eNOS-independent protective actions against angiotensin II induced cardiovascular remodeling and renal insufficiency.
    Circulation research, 2008, Jan-04, Volume: 102, Issue:1

    Topics: Angiotensin II; Animals; Cardiotonic Agents; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Oxidative Stress; Quinolines; Renal Insufficiency; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ventricular Remodeling

2008
Endothelial nitric oxide synthase-independent protective action of statin against angiotensin II-induced atrial remodeling via reduced oxidant injury.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:4

    Topics: Analysis of Variance; Angiotensin II; Animals; Antioxidants; Atrial Fibrillation; Blood Pressure; Blotting, Western; Cardiomegaly; Cyclic N-Oxides; Echocardiography; Fibrosis; Heart Atria; Heart Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide Synthase Type III; Oxidative Stress; Quinolines; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Smad2 Protein; Smad3 Protein; Spin Labels; Transforming Growth Factor beta1

2010
Pitavastatin-attenuated cardiac dysfunction in mice with dilated cardiomyopathy via regulation of myocardial calcium handling proteins.
    Acta pharmaceutica (Zagreb, Croatia), 2014, Volume: 64, Issue:1

    Topics: Angiotensin II; Animals; Calcium; Cardiomyopathy, Dilated; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Myocardium; Natriuretic Peptide, Brain; Peptide Fragments; Protein Kinase C beta; Quinolines; Random Allocation; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases

2014
Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apoe
    Journal of atherosclerosis and thrombosis, 2022, Jan-01, Volume: 29, Issue:1

    Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Chemokine CCL2; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Monocytes; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines

2022