Compounds > angiotensin ii
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angiotensin ii and pd 98059

angiotensin ii has been researched along with pd 98059 in 110 studies

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (17.27)18.2507
2000's74 (67.27)29.6817
2010's17 (15.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Giasson, E; Meloche, S; Servant, MJ1
Abraham, ST; Baker, KM; Bhat, GJ1
Gould, GW; Plevin, R; Robinson, CJ; Scott, PH1
Boarder, MR; Morton, C; Ng, LL; Wilkie, N1
Lu, D; Raizada, MK; Vinson, GP; Yang, H1
Baker, KM; Bhat, GJ1
Lu, D; Raizada, MK; Yang, H1
Aikawa, R; Komuro, I; Kudoh, S; Nagai, R; Uozumi, H; Yamazaki, T; Yazaki, Y; Zou, Y1
Florian, JA; Monroe, KM; Watts, SW1
Anand-Srivastava, MB; Ge, C1
Akishita, M; Daviet, L; Dzau, VJ; Horiuchi, M; Ito, M; Lehtonen, JY1
Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Law, RE; Xi, XP1
Deng, LY; He, G; Schiffrin, EL; Touyz, RM1
El Mabrouk, M; He, G; Schiffrin, EL; Touyz, RM; Wu, XH1
Marsh, JD; Ritchie, RH; Schiebinger, RJ1
Hamaguchi, A; Iwao, H; Izumi, Y; Kim, S; Yamanaka, S; Zhan, Y1
Asselin, C; Gallo-Payet, N; Gendron, L; Laflamme, L; Payet, MD; Rivard, N1
Grohé, C; Löbbert, K; Stimpel, M; van Eickels, M; Vetter, H1
Lei, J; Medve, I; Neugarten, J; Silbiger, SR1
Bouillier, H; Dagher, G; Miserey, S; Perret, C; Renaud, JF; Safar, M; Samain, E1
Akimoto, K; Hattori, Y; Kasai, K1
Hannken, T; Schroeder, R; Stahl, RAK; Wolf, G; Zahner, G1
Chatziantoniou, C; Dussaule, JC; Fakhouri, F; Tharaux, PL1
Benter, IF; Estes, A; Gaber, L; Karzoun, NA; Khandekar, Z; Malik, KU; Muthalif, MM; Parmentier, JH; Saeed, AE1
Eskildsen-Helmond, YE; Fiebeler, A; Henrion, D; Levy, BI; Matrougui, K; Mulvany, MJ; Tedgui, A1
Funakoshi, Y; Ichiki, T; Iino, N; Ito, K; Takeda, K; Takeshita, A; Tokunou, T1
Ding, B; Huang, SL; Li, YX; Zhang, SQ1
Diep, Q; El Mabrouk, M; He, G; Mardigyan, V; Schiffrin, EL; Touyz, RM1
Fujii, S; Ichiki, T; Iino, N; Kitabatake, A; Shimokawa, H; Takeda, K; Takeshita, A; Tokunou, T1
Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T1
Bobrovskaya, L; Dunkley, PR; Leal, RB; Odell, A1
Garcha, RS; Hughes, AD; Sever, PS1
Chen, H; Li, D; Mehta, JL1
Goodchild, AK; Pilowsky, PM; Seyedabadi, M1
Ertl, G; Jacobs, M; Scheuren, N; Schorb, W1
Christoffersen, T; Hege Thoresen, G; Nilssen, LS; Sandnes, D1
Funakoshi, Y; Ichiki, T; Iino, N; Takeda, K; Takeshita, A; Tokuno, T1
Fan, YP; Puri, RN; Rattan, S2
Chen, X; Deschepper, C; He, G; Neves, MF; Park, JB; Schiffrin, EL; Touyz, RM; Virdis, A1
Freeman, EJ; Silfani, TN1
Block, ER; Li, YD; Patel, JM1
Baker, KM; Booz, GW; Day, JN1
Isozumi, K; Nakashima, Y; Okazaki, M; Tamura, K; Tamura, M; Tasaki, H1
de Champlain, J; El Midaoui, A; Laplante, MA; Wu, R1
Shukla, SD; Weng, YI1
Clark, BJ; Dawson, KL; Feltzer, RE; Hudson, EA; Li, J1
Chayama, K; Ishida, M; Ishida, T; Kambe, M; Miho, N; Miyagawa, K; Nakashima, H; Oshima, T; Yoshizumi, M1
Capuano, V; Coulombe, A; Deroubaix, E; Ferron, L; Renaud, JF; Ruchon, Y1
Chen, HC; Feener, EP1
Akioka, K; Ichijo, H; Iwao, H; Izumi, Y; Kim, S; Matsumoto, R; Nakamura, Y; Omura, T; Sudo, T; Takeuchi, K; Yoshikawa, J; Yoshiyama, M1
Ago, T; Iida, M; Iwase, M; Kitazono, T; Nakamura, U; Ueta, M; Wakisaka, M; Yoshinari, M1
Hama, K; Hanatsuka, K; Kita, H; Mashima, H; Ohashi, A; Ohnishi, H; Satoh, Y; Sugano, K; Tamada, K; Ueda, N; Yasuda, H1
Fukuda, K; Ita, M; Kato, T; Miyoshi, S; Murata, M; Ogawa, S; Takahashi, E; Tanabe, T1
Garnovskaya, MN; Grewal, JS; Mukhin, YV; Raymond, JR; Tholanikunnel, BG; Ullian, ME; Vlasova, TM1
Drexler, H; Fuchs, M; Grote, K; Hilfiker, A; Hilfiker-Kleiner, D; Kaminska, A; Kaminski, K; Kiian, I; Klein, G; Podewski, E; Wollert, KC1
Daigle, C; Dao, HH; Girardot, D; Martens, FM; Moreau, P; Touyz, RM1
Cheng, LJ; Huang, HC; Liang, Y1
Ingelfinger, JR; Moini, B; Zhang, SL1
Bounoua, F; Corry, DB; Eggena, P; Eslami, P; Nyby, MD; Tuck, ML1
Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL1
Lefebvre, A; LeHoux, JG1
Bird, IM; Chen, DB; Magness, RR; Wen, Y; Zheng, J1
Akioka, K; Enomoto, S; Ichijo, H; Iwao, H; Izumi, Y; Kim, S; Kusuyama, T; Matsumoto, R; Motojima, M; Nishiya, D; Omura, T; Takeuchi, K; Yoshikawa, J; Yoshiyama, M1
Hatano, Y; Mizumoto, K; Ogawa, K; Tokinaga, Y; Yu, J1
Corvol, P; Hus-Citharel, A; Iturrioz, X; Llorens-Cortes, C; Marchetti, J1
Hinson, JP; McNeill, H; Vinson, GP; Whitworth, E1
Hayashi, K; Iwamoto, K; Kizawa, Y; Koike, K; Murakami, H; Ohsawa, M; Ohuchi, N; Taniguchi, Y1
Block, ER; Lu, J; Patel, JM; Zhang, J1
Kawamoto, T; Kita, T; Nakashima, Y; Tanaka, M; Togi, K; Yamauchi, R; Yoshida, Y1
Hirase, T; Inoue, T; Node, K; Wang, D1
Anand-Srivastava, MB; Hashim, S; Li, Y2
Im, CN; Seo, JS; Zheng, Y1
Bell, RM; Clark, JE; Hearse, DJ; Shattock, MJ1
Marsigliante, S; Muscella, A; Romano, S; Storelli, C1
Griffin, AJ; Gupta, M; Kumbar, DH; Muangmingsuk, S; Ocampo, C; VanBergen, A1
Goalstone, ML; Sharma, G1
Boyd, R; Chapman, A; Ding, L; Wang, HD1
Agrawal, DK; Cheng, G; Gangahar, DM; Jia, G; Mitra, AK1
Castejon, AM; Chiarello, R; Clark, MA; Delaney, J; Kandalam, U; Villar, D1
Bae, YM; Kim, B; Lee, CK; Lee, HM; Lee, KY; Lee, SH; Lee, YL; Lim, J; Park, PJ; Park, TK; Roh, HY; Won, KJ1
Andresen, BT; Escano, CS; Gutweiler, AA; Keever, LB1
Ahn, HY; Chae, YJ; Ha, TS; Hescheler, J; Kim, CH; Sachinidis, A1
Felder, RB; Wei, SG; Weiss, RM; Yu, Y; Zhang, ZH1
Hirafuji, M; Iizuka, K; Kawaguchi, H; Machida, T1
Ferrario, CM; Gallagher, PE; Tallant, EA2
Jing, L; Kou, JJ; Li, S; Li, WM; Song, J; Zhou, LJ1
Ishida, K; Kamata, K; Kobayashi, T; Matsumoto, T; Nakayama, N1
Akiyoshi, Y; Miyamoto, S; Morishima, M; Ono, K; Wang, Y1
Han, M; He, M; Shu, YN; Wen, JK; Zheng, B1
Cheng, PW; Cheng, WH; Ho, WY; Hsiao, M; Lu, PJ; Tseng, CJ; Tung, CS1
Dominici, FP; Fernández, BE; Giani, JF; Höcht, C; Mayer, MA; Muñoz, MC; Puyó, AM; Silberman, EA; Taira, CA1
Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B1
Clark, MA; Nguyen, C; Tran, H1
Fu, GX; Gao, PJ; Jin, X; Li, XD; Zhu, DL1
Snyder, R; Thekkumkara, T1
Chen, P; Tee, WT; Than, A1
Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K1
Ge, J; Gong, H; Guan, A; Jia, J; Li, B; Niu, Y; Qian, S; Ye, Y; Zhang, G; Zou, Y1
Kong, XQ; Wang, T; Wang, WH1
Chiu, CZ; Shyu, KG; Wang, BW1
Deng, Y; Guo, XL; Liu, HG; Liu, K; Shang, J; Xu, YJ1
Lin, YQ; Luo, NS; Mai, J; Qiu, Q; Wang, JF; Wen, ZZ; YangXin, C; Zhang, HF1
Bruder-Nascimento, T; Callera, GE; Cau, SB; Chinnasamy, P; Riascos-Bernal, DF; Sibinga, NE; Tostes, RC; Touyz, RM1
Chen, C; Du, J; Li, HH; Meng, Y; Tian, C1
Bai, T; Chi, L; Guo, R; Hu, X; Tian, H; Zeng, H; Zhang, L; Zhang, W; Zhang, Y1
Cai, W; Cai, X; Gao, F; Huang, D; Lan, J; Shi, G; Xu, H; Zhang, Y; Zheng, F; Zhong, S1

Other Studies

110 other study(ies) available for angiotensin ii and pd 98059

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells.
    The Journal of biological chemistry, 1996, Jul-05, Volume: 271, Issue:27

    Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Growth Substances; Insulin; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Phosphorylation; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Rats; Sirolimus; Substrate Specificity; Tetradecanoylphorbol Acetate; Thrombin

1996
Angiotensin II interferes with interleukin 6-induced Stat3 signaling by a pathway involving mitogen-activated protein kinase kinase 1.
    The Journal of biological chemistry, 1996, Sep-13, Volume: 271, Issue:37

    Topics: Angiotensin II; Animals; Basic-Leucine Zipper Transcription Factors; Cells, Cultured; Cricetinae; DNA-Binding Proteins; Drosophila Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flavonoids; Interleukin-6; Leucine Zippers; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; STAT3 Transcription Factor; Tetradecanoylphorbol Acetate; Trans-Activators; Transcription Factors

1996
Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells.
    The Biochemical journal, 1996, Sep-01, Volume: 318 ( Pt 2)

    Topics: Angiotensin II; Animals; Aorta; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Line; Cells, Cultured; Colforsin; DNA; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Trachea

1996
Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II. A role for phospholipase D.
    The Journal of biological chemistry, 1996, Dec-13, Volume: 271, Issue:50

    Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phospholipase D; Protein-Tyrosine Kinases; Rats; Thymidine

1996
Involvement of MAP kinase in angiotensin II-induced phosphorylation and intracellular targeting of neuronal AT1 receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Mar-01, Volume: 17, Issue:5

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Biological Transport; Biphenyl Compounds; Brain Stem; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Hypothalamus; Imidazoles; Losartan; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phosphorylation; Plant Proteins; Protein Processing, Post-Translational; Rats; Rats, Inbred WKY; Signal Transduction; Tetrazoles

1997
Angiotensin II stimulates rapid serine phosphorylation of transcription factor Stat3.
    Molecular and cellular biochemistry, 1997, Volume: 170, Issue:1-2

    Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; CHO Cells; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Flavonoids; Kinetics; Mitogen-Activated Protein Kinase Kinases; Myocardium; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Angiotensin; Recombinant Proteins; Serine; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transfection

1997
Angiotensin II-induced phosphorylation of the AT1 receptor from rat brain neurons.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:3 Pt 1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Animals, Newborn; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Neurons; Phosphorylation; Precipitin Tests; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin

1997
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
    Circulation research, 1998, Mar-09, Volume: 82, Issue:4

    Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cytoplasm; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Guanidines; Hydrogen-Ion Concentration; Ion Channels; MAP Kinase Kinase 1; Mechanoreceptors; Mitogen-Activated Protein Kinase Kinases; Muscle Proteins; Peptides, Cyclic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Tetrazoles

1998
Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: Angiotensin II; Animals; Aorta; Enzyme Activation; Flavonoids; Genistein; In Vitro Techniques; Male; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Nitriles; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tyrphostins; Vasoconstriction

1998
Involvement of phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways in AII-mediated enhanced expression of Gi proteins in vascular smooth muscle cells.
    Biochemical and biophysical research communications, 1998, Oct-20, Volume: 251, Issue:2

    Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dactinomycin; Embryo, Mammalian; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gi-Go; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Protein Biosynthesis; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Transcription, Genetic; Wortmannin

1998
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:1

    Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Culture Media; DNA; Female; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; Losartan; Mice; Mice, Knockout; Muscle Development; Muscle, Smooth, Vascular; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Binding; Pyridines; Receptors, Angiotensin; Vanadates

1999
Central role of the MAPK pathway in ang II-mediated DNA synthesis and migration in rat vascular smooth muscle cells.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:1

    Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; DNA; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction

1999
Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries.
    Circulation, 1999, Jan-26, Volume: 99, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Calcium; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Flavonoids; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Receptors, Angiotensin; Tyrosine; Tyrphostins; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

1999
Mitogen-activated protein/extracellular signal-regulated kinase inhibition attenuates angiotensin II-mediated signaling and contraction in spontaneously hypertensive rat vascular smooth muscle cells.
    Circulation research, 1999, Mar-19, Volume: 84, Issue:5

    Topics: Angiotensin II; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Hydrogen-Ion Concentration; Hypertension; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents

1999
Bradykinin-stimulated protein synthesis by myocytes is dependent on the MAP kinase pathway and p70(S6K).
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Angiotensin II; Animals; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus

1999
Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hypertension; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Phosphorylation; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Transcription Factor AP-1; Transforming Growth Factor beta

1999
Signals from the AT2 (angiotensin type 2) receptor of angiotensin II inhibit p21ras and activate MAPK (mitogen-activated protein kinase) to induce morphological neuronal differentiation in NG108-15 cells.
    Molecular endocrinology (Baltimore, Md.), 1999, Volume: 13, Issue:9

    Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression; Mutation; Neurites; Neurons; Phosphoproteins; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins p21(ras); Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Transfection; Tumor Cells, Cultured

1999
Angiotensin converting enzyme inhibitors block mitogenic signalling pathways in rat cardiac fibroblasts.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 359, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Flavonoids; Heart; Immunoblotting; Isoquinolines; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; STAT3 Transcription Factor; Tetrahydroisoquinolines; Tetrazoles; Time Factors; Trans-Activators

1999
Estradiol suppresses mesangial cell type I collagen synthesis via activation of the MAP kinase cascade.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Angiotensin II; Animals; Cell Nucleus; Cells, Cultured; Collagen; Enzyme Inhibitors; Estradiol; Flavonoids; Gene Expression Regulation; Glomerular Mesangium; Kinetics; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Transcription Factor AP-1

1999
Extracellular signal-regulated kinase pathway is involved in basic fibroblast growth factor effect on angiotensin II-induced Ca(2+) transient in vascular smooth muscle cell from Wistar-Kyoto and spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 1

    Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cell Size; DNA; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Hypertension; In Vitro Techniques; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin

2000
The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II.
    Biochemical and biophysical research communications, 2000, Jul-14, Volume: 273, Issue:3

    Topics: Angiotensin II; Animals; Enzyme Inhibitors; Flavonoids; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Thiazoles; Transcription Factor AP-1

2000
Reactive oxygen species stimulate p44/42 mitogen-activated protein kinase and induce p27(Kip1): role in angiotensin II-mediated hypertrophy of proximal tubular cells.
    Journal of the American Society of Nephrology : JASN, 2000, Volume: 11, Issue:8

    Topics: Angiotensin II; Animals; Cell Cycle Proteins; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Inhibitors; Flavonoids; Hydrogen Peroxide; Hypertrophy; Kidney Tubules, Proximal; LLC-PK1 Cells; Mice; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Phosphorylation; Reactive Oxygen Species; Swine; Tumor Suppressor Proteins

2000
Angiotensin II activates collagen I gene through a mechanism involving the MAP/ER kinase pathway.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Collagen; Decorin; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix Proteins; Flavonoids; Gene Expression Regulation, Enzymologic; Genes, fos; Genetic Markers; Humans; Imidazoles; Kidney; Luciferases; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proteoglycans; Proto-Oncogene Mas; Pyridines; Tetrazoles; Transcriptional Activation; Transforming Growth Factor beta

2000
Angiotensin II-induced hypertension: contribution of Ras GTPase/Mitogen-activated protein kinase and cytochrome P450 metabolites.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Alkyl and Aryl Transferases; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Enzyme Inhibitors; Flavonoids; Hypertension; Kidney; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mixed Function Oxygenases; ras Proteins; Rats; Rats, Sprague-Dawley; Triazoles

2000
Angiotensin II stimulates extracellular signal-regulated kinase activity in intact pressurized rat mesenteric resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myography; Phenylephrine; Phosphorylation; Potassium; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Vascular Resistance; Vasoconstriction

2000
Reactive oxygen species-mediated homologous downregulation of angiotensin II type 1 receptor mRNA by angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antioxidants; Binding, Competitive; Cells, Cultured; Down-Regulation; Enzyme Activation; Flavonoids; Gene Expression Regulation; Hydrogen Peroxide; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transfection

2001
Effect of PKC-zeta mediating Ang II-stimulated activation of CCDPK on rat cardiac fibroblast proliferation.
    Acta pharmacologica Sinica, 2000, Volume: 21, Issue:2

    Topics: Angiotensin II; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Epidermal Growth Factor; Fibroblasts; Flavonoids; Isoenzymes; Mitogen-Activated Protein Kinase Kinases; Myocardium; Protein Kinase C; Rats; Tetradecanoylphorbol Acetate

2000
Differential activation of extracellular signal-regulated protein kinase 1/2 and p38 mitogen activated-protein kinase by AT1 receptors in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats.
    Journal of hypertension, 2001, Volume: 19, Issue:3 Pt 2

    Topics: Angiotensin II; Animals; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hypertension; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; RNA, Messenger; Vasoconstrictor Agents

2001
Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression.
    Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:5

    Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; RNA Processing, Post-Transcriptional; RNA, Messenger; Up-Regulation

2001
Mildly oxidized low-density lipoprotein acts synergistically with angiotensin II in inducing vascular smooth muscle cell proliferation.
    Journal of hypertension, 2001, Volume: 19, Issue:6

    Topics: Acetylcysteine; Aldehydes; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Benzimidazoles; Biphenyl Compounds; Cardiovascular Diseases; Cell Division; Cells, Cultured; DNA; Drug Synergism; Flavonoids; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Muscle, Smooth, Vascular; Probucol; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Tyrphostins

2001
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
    Journal of neurochemistry, 2001, Volume: 78, Issue:3

    Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase

2001
Mechanism of action of angiotensin II in human isolated subcutaneous resistance arteries.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: Amlodipine; Angiotensin II; Arteries; Benzimidazoles; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Flavonoids; Genistein; Humans; In Vitro Techniques; Nickel; Norepinephrine; Potassium; Ryanodine; Skin; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

2001
Angiotensin II via activation of type 1 receptor upregulates expression of endoglin in human coronary artery endothelial cells.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antigens, CD; Cells, Cultured; Coronary Vessels; Endoglin; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Humans; Losartan; Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation; Vascular Cell Adhesion Molecule-1

2001
Differential role of kinases in brain stem of hypertensive and normotensive rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:5

    Topics: Androstadienes; Angiotensin II; Animals; Apnea; Blood Pressure; Brain Stem; Enzyme Inhibitors; Flavonoids; Glutamic Acid; Hypertension; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstrictor Agents; Wortmannin

2001
Cyclooxygenase-2 in myocardium stimulation by angiotensin-II in cultured cardiac fibroblasts and role at acute myocardial infarction.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:1

    Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Egg Proteins; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Imidazoles; Immunoblotting; Immunoenzyme Techniques; Immunohistochemistry; Isoenzymes; Lactones; Macrophages; Membrane Glycoproteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Myocardium; Necrosis; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Sulfones; Time Factors; Vimentin; Zona Pellucida Glycoproteins

2002
Differential role of MAP kinases in stimulation of hepatocyte growth by EGF and G-protein-coupled receptor agonists.
    Biochemical and biophysical research communications, 2002, Mar-01, Volume: 291, Issue:3

    Topics: Angiotensin II; Animals; Cell Division; Dinoprost; DNA; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocytes; Heterotrimeric GTP-Binding Proteins; Imidazoles; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Vasopressins

2002
Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells.
    The Journal of biological chemistry, 2002, May-24, Volume: 277, Issue:21

    Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Flavonoids; Imidazoles; Muscle, Smooth, Vascular; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Transcription, Genetic

2002
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
    Life sciences, 2002, Mar-22, Volume: 70, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins

2002
Inhibition of mitogen-activated protein/extracellular signal-regulated kinase improves endothelial function and attenuates Ang II-induced contractility of mesenteric resistance arteries from spontaneously hypertensive rats.
    Journal of hypertension, 2002, Volume: 20, Issue:6

    Topics: Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Hypertension; Mesenteric Arteries; Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2002
Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.
    Archives of biochemistry and biophysics, 2002, Jun-01, Volume: 402, Issue:1

    Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Cells, Cultured; Chromones; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Male; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Rats, Sprague-Dawley

2002
Role of pp60(c-src) and p(44/42) MAPK in ANG II-induced contraction of rat tonic gastrointestinal smooth muscles.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:2

    Topics: Angiotensin II; Animals; Antibodies; Benzoquinones; Calmodulin-Binding Proteins; Digestive System; Digestive System Physiological Phenomena; Enzyme Inhibitors; Female; Flavonoids; Genistein; In Vitro Techniques; Lactams, Macrocyclic; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth; p120 GTPase Activating Protein; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; Tyrosine

2002
Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.
    American journal of physiology. Lung cellular and molecular physiology, 2002, Volume: 283, Issue:4

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Angiotensin II; Animals; Anti-Bacterial Agents; Cell Division; Cells, Cultured; Endothelium; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Swine; Wortmannin

2002
Angiotensin II effects on STAT3 phosphorylation in cardiomyocytes: evidence for Erk-dependent Tyr705 dephosphorylation.
    Basic research in cardiology, 2003, Volume: 98, Issue:1

    Topics: Angiotensin II; Animals; Animals, Newborn; DNA-Binding Proteins; Flavonoids; Interleukin-6; Leukemia Inhibitory Factor; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Phosphotyrosine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Vanadates

2003
Urotensin II-induced activation of extracellular signal-regulated kinase in cultured vascular smooth muscle cells: involvement of cell adhesion-mediated integrin signaling.
    Life sciences, 2003, Jan-17, Volume: 72, Issue:9

    Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Flavonoids; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Urotensins

2003
NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.
    Journal of hypertension, 2003, Volume: 21, Issue:5

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Vasoconstrictor Agents

2003
Effects of chronic ethanol treatment on the angiotensin II-mediated p42/p44 mitogen-activated protein kinase and phosphorylase a activation in rat hepatocytes.
    Alcohol (Fayetteville, N.Y.), 2003, Volume: 29, Issue:2

    Topics: Angiotensin II; Animals; Calcium; Cell Separation; Central Nervous System Depressants; Enzyme Activation; Enzyme Inhibitors; Ethanol; Flavonoids; Hepatocytes; Immunoblotting; Male; Mitogen-Activated Protein Kinase 1; Phosphorylase a; Rats; Rats, Sprague-Dawley; Signal Transduction

2003
Janus kinase 2 and calcium are required for angiotensin II-dependent activation of steroidogenic acute regulatory protein transcription in H295R human adrenocortical cells.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Adrenal Cortex; Angiotensin II; Calcium; Cell Line; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Genes, Reporter; Humans; Immunoblotting; Janus Kinase 2; Luciferases; Phosphoproteins; Progesterone; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Radioimmunoassay; RNA, Messenger; Signal Transduction; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrphostins

2003
Mnk1 is required for angiotensin II-induced protein synthesis in vascular smooth muscle cells.
    Circulation research, 2003, Dec-12, Volume: 93, Issue:12

    Topics: Angiotensin II; Aniline Compounds; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Flavonoids; Imidazoles; Immunoblotting; Male; Muscle, Smooth, Vascular; Mutation; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Purines; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction

2003
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
    Circulation research, 2003, Dec-12, Volume: 93, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; Calcium Channels, T-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Constriction, Pathologic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Gene Expression; Losartan; Male; Membrane Potentials; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nickel; Nitriles; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Sulfonamides

2003
MEK1,2 response element mediates angiotensin II-stimulated plasminogen activator inhibitor-1 promoter activation.
    Blood, 2004, Apr-01, Volume: 103, Issue:7

    Topics: Adenoviridae; Angiotensin II; Base Sequence; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genetic Vectors; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase Kinases; Plasmids; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Transcription Factors

2004
Involvement of apoptosis signal-regulating kinase-1 on angiotensin II-induced monocyte chemoattractant protein-1 expression.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:2

    Topics: Adenoviridae; Angiotensin II; Animals; Animals, Newborn; Cells, Cultured; Chemokine CCL2; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Heart Ventricles; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle Cells; Mutation; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Transduction, Genetic

2004
PPARgamma ligands attenuate mesangial contractile dysfunction in high glucose.
    Kidney international, 2004, Volume: 65, Issue:3

    Topics: Actins; Angiotensin II; Animals; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; DNA, Antisense; Enzyme Inhibitors; Flavonoids; Gene Expression; Glomerular Mesangium; Glucose; Hypoglycemic Agents; Indomethacin; Ligands; Pioglitazone; Prostaglandin D2; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors; Vasoconstrictor Agents

2004
Angiotensin II stimulates DNA synthesis of rat pancreatic stellate cells by activating ERK through EGF receptor transactivation.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; DNA; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Losartan; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Pancreas; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Thymidine; Transcriptional Activation; Tritium

2004
Leukemia inhibitory factor activates cardiac L-Type Ca2+ channels via phosphorylation of serine 1829 in the rabbit Cav1.2 subunit.
    Circulation research, 2004, May-14, Volume: 94, Issue:9

    Topics: Amino Acid Substitution; Angiotensin II; Animals; Animals, Newborn; Aorta; Calcium; Calcium Channels, L-Type; Cell Line; Cells, Cultured; Consensus Sequence; Flavonoids; Humans; Interleukin-6; Kidney; Leukemia Inhibitory Factor; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Protein Structure, Tertiary; Rabbits; Rats; Rats, Wistar; Recombinant Proteins; Sequence Deletion; Species Specificity; Transfection

2004
Mitogen-induced rapid phosphorylation of serine 795 of the retinoblastoma gene product in vascular smooth muscle cells involves ERK activation.
    The Journal of biological chemistry, 2004, Jun-04, Volume: 279, Issue:23

    Topics: Androstadienes; Angiotensin II; Animals; Aorta; Blotting, Western; Cell Membrane; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Immunoblotting; Mitogen-Activated Protein Kinases; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Rats; Retinoblastoma Protein; Serine; Serotonin; Time Factors; Wortmannin

2004
Regulation of proangiogenic factor CCN1 in cardiac muscle: impact of ischemia, pressure overload, and neurohumoral activation.
    Circulation, 2004, May-11, Volume: 109, Issue:18

    Topics: Alkaloids; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Benzophenanthridines; Cell Movement; Cells, Cultured; Cysteine-Rich Protein 61; Flavonoids; Gene Expression Regulation; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Interleukin-6; Leukemia Inhibitory Factor; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Myocytes, Smooth Muscle; Naphthalenes; Neovascularization, Physiologic; Norepinephrine; Paracrine Communication; Phenanthridines; Phenylephrine; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Messenger; Stress, Mechanical; Telmisartan; Tumor Necrosis Factor-alpha

2004
Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo.
    BMC cardiovascular disorders, 2004, May-10, Volume: 4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Flavonoids; Irbesartan; Leucine; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Tetrazoles

2004
[Transforming growth factor beta 1 modulates connective tissue growth factor expression via Smad2 signaling pathway in podocyte in vitro].
    Zhonghua yi xue za zhi, 2004, Apr-02, Volume: 84, Issue:7

    Topics: Angiotensin II; Blotting, Western; Cells, Cultured; Connective Tissue Growth Factor; DNA-Binding Proteins; Flavonoids; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1

2004
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
    Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:6

    Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation

2004
Insulin stimulates endogenous angiotensin II production via a mitogen-activated protein kinase pathway in vascular smooth muscle cells.
    Journal of hypertension, 2004, Volume: 22, Issue:9

    Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta; Cell Division; Cells, Cultured; Cytosol; Enzyme Inhibitors; Flavonoids; Hypoglycemic Agents; Immunohistochemistry; Insulin; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger

2004
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
    Circulation research, 2004, Dec-10, Volume: 95, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan

2004
On the control of the hCYP11B2 gene expressing cytochrome P450 aldosterone synthase.
    Endocrine research, 2004, Volume: 30, Issue:4

    Topics: Angiotensin II; Cell Line, Tumor; Cytochrome P-450 CYP11B2; Flavonoids; Gene Expression Regulation; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

2004
Angiotensin II elevates nitric oxide synthase 3 expression and nitric oxide production via a mitogen-activated protein kinase cascade in ovine fetoplacental artery endothelial cells.
    Biology of reproduction, 2005, Volume: 72, Issue:6

    Topics: Angiotensin II; Animals; Arteries; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Fetus; Flavonoids; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Placenta; Pregnancy; Sheep, Domestic

2005
Role of c-Jun NH2-terminal kinase in G-protein-coupled receptor agonist-induced cardiac plasminogen activator inhibitor-1 expression.
    Journal of molecular and cellular cardiology, 2005, Volume: 38, Issue:4

    Topics: Angiotensin II; Animals; Fibroblasts; Flavonoids; Gene Expression Regulation; Heart Ventricles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; Mutation; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Plasminogen Activator Inhibitor 1; Protein Kinase Inhibitors; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger

2005
The inhibitory effects of sevoflurane on angiotensin II- induced, p44/42 mitogen-activated protein kinase-mediated contraction of rat aortic smooth muscle.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Anesthetics, Inhalation; Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Dose-Response Relationship, Drug; Flavonoids; In Vitro Techniques; Isometric Contraction; Male; Methyl Ethers; Mitogen-Activated Protein Kinase 3; Muscle Contraction; Muscle, Smooth, Vascular; Phosphorylation; Rats; Sevoflurane; Vasoconstrictor Agents

2005
Tyrosine kinase and mitogen-activated protein kinase/extracellularly regulated kinase differentially regulate intracellular calcium concentration responses to angiotensin II/III and bradykinin in rat cortical thick ascending limb.
    Endocrinology, 2006, Volume: 147, Issue:1

    Topics: Angiotensin II; Angiotensin III; Animals; Bradykinin; Calcium; Cerebral Cortex; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Kinetics; Male; Mitogen-Activated Protein Kinase 1; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley

2006
Distribution of extracellular signal-regulated protein kinases 1 and 2 in the rat adrenal and their activation by angiotensin II.
    The Journal of endocrinology, 2005, Volume: 187, Issue:1

    Topics: Adrenal Glands; Angiotensin II; Animals; Cell Division; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Immunoblotting; Immunohistochemistry; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Radioimmunoassay; Rats; Rats, Wistar; Staining and Labeling; Time Factors

2005
Inhibition of angiotensin II- and endothelin-1-stimulated proliferation by selective MEK inhibitor in cultured rabbit gingival fibroblastsdagger.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:6

    Topics: Angiotensin II; Animals; Blotting, Western; Butadienes; Cell Proliferation; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; MAP Kinase Kinase Kinases; Nitriles; Peptides, Cyclic; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Saralasin

2005
Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells.
    Molecular and cellular biochemistry, 2005, Volume: 275, Issue:1-2

    Topics: Angiotensin II; Animals; Carrier Proteins; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Swine

2005
Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes.
    International journal of molecular medicine, 2006, Volume: 18, Issue:1

    Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Carrier Proteins; Cells, Cultured; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression; Homer Scaffolding Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Protein Isoforms; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors

2006
Atorvastatin inhibits angiotensin II-induced T-type Ca2+ channel expression in endothelial cells.
    Biochemical and biophysical research communications, 2006, Aug-25, Volume: 347, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Benzimidazoles; Biphenyl Compounds; Calcium Channels, T-Type; Cells, Cultured; Endothelial Cells; Flavonoids; Gene Expression; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Microscopy, Fluorescence; Pyrroles; ras Proteins; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tetrazoles; Vasoconstrictor Agents

2006
Small cytoplasmic domain peptides of natriuretic peptide receptor-C attenuate cell proliferation through Gialpha protein/MAP kinase/PI3-kinase/AKT pathways.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:6

    Topics: Amino Acid Sequence; Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Cell Line; Cell Proliferation; Endothelin-1; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Receptors, Atrial Natriuretic Factor; Signal Transduction; Vasoconstrictor Agents; Wortmannin

2006
Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqalpha/MAP kinase signaling pathways.
    Cardiovascular research, 2006, Dec-01, Volume: 72, Issue:3

    Topics: Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blotting, Western; Cell Line; Cell Proliferation; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Flavonoids; GTP-Binding Protein alpha Subunits, Gq-G11; Leucine; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Stimulation, Chemical; Wortmannin

2006
Inhibitory effect of Hsp70 on angiotensin II-induced vascular smooth muscle cell hypertrophy.
    Experimental & molecular medicine, 2006, Oct-31, Volume: 38, Issue:5

    Topics: Angiotensin II; Animals; Aorta; Cell Cycle Proteins; Cells, Cultured; Dual Specificity Phosphatase 1; Enzyme Stability; Flavonoids; HSP70 Heat-Shock Proteins; Hypertrophy; Immediate-Early Proteins; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; RNA, Small Interfering

2006
Reperfusion kinase phosphorylation is essential but not sufficient in the mediation of pharmacological preconditioning: Characterisation in the bi-phasic profile of early and late protection.
    Cardiovascular research, 2007, Jan-01, Volume: 73, Issue:1

    Topics: Androstadienes; Angiotensin II; Animals; Blotting, Western; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Inbred C57BL; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oncogene Protein v-akt; Perfusion; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Time Factors; Wortmannin

2007
Angiotensin II does not stimulate proliferation of rat thyroid PC Cl3 cell line.
    The Journal of endocrinology, 2006, Volume: 191, Issue:3

    Topics: Angiotensin II; Animals; Cell Line; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Indoles; Insulin; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Rats; RNA Interference; Signal Transduction; Thyroid Gland

2006
Adapter molecule DOC-2 is differentially expressed in pressure and volume overload hypertrophy and inhibits collagen synthesis in cardiac fibroblasts.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Cardiomegaly; Cells, Cultured; Collagen; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gene Expression; Ligation; Myocytes, Cardiac; Phorbol Esters; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Transfection; Ventricular Remodeling

2007
Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells.
    Biochemical and biophysical research communications, 2007, Mar-23, Volume: 354, Issue:4

    Topics: Androstadienes; Angiotensin II; Animals; Enzyme Activation; Flavonoids; Insulin; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 7; Muscle, Smooth, Vascular; Myogenic Regulatory Factors; Phosphorylation; Rats; Wortmannin

2007
ERK activation contributes to regulation of spontaneous contractile tone via superoxide anion in isolated rat aorta of angiotensin II-induced hypertension.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 292, Issue:6

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Butadienes; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Flavonoids; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Superoxides; Vasoconstriction

2007
Angiotensin II and IGF-1 regulate connexin43 expression via ERK and p38 signaling pathways in vascular smooth muscle cells of coronary artery bypass conduits.
    The Journal of surgical research, 2007, Volume: 142, Issue:1

    Topics: Aged; Angiotensin II; Cell Proliferation; Cells, Cultured; Connexin 43; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Pyridines; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents

2007
Regulation of c-fos, c-jun and c-myc gene expression by angiotensin II in primary cultured rat astrocytes: role of ERK1/2 MAP kinases.
    Neurochemical research, 2008, Volume: 33, Issue:3

    Topics: Actins; Angiotensin II; Animals; Astrocytes; Brain Stem; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, myc; Mitogen-Activated Protein Kinases; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger

2008
p38 mitogen-activated protein kinase contributes to angiotensin II-stimulated migration of rat aortic smooth muscle cells.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:1

    Topics: Actins; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Syk Kinase; Vasoconstrictor Agents

2007
Angiotensin II activates extracellular signal-regulated kinase independently of receptor tyrosine kinases in renal smooth muscle cells: implications for blood pressure regulation.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 324, Issue:1

    Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Kidney; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Quinazolines; Rats; Rats, Inbred WKY; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Tyrphostins; Vasoconstrictor Agents

2008
Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK pathways.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:6

    Topics: Angiotensin II; Catechin; Cell Membrane; Endothelial Cells; Enzyme Activation; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Umbilical Veins; Vascular Cell Adhesion Molecule-1

2007
Angiotensin II-triggered p44/42 mitogen-activated protein kinase mediates sympathetic excitation in heart failure rats.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 52, Issue:2

    Topics: Acute Disease; Analysis of Variance; Angiotensin II; Animals; Chronic Disease; Disease Models, Animal; Flavonoids; Fluorescent Antibody Technique; Heart Failure; Hemodynamics; Immunohistochemistry; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction; Sympathetic Nervous System

2008
Pulsatile mechanical pressure promotes Angiotensin-converting enzyme expression in aortic smooth muscle cells.
    Cardiovascular drugs and therapy, 2008, Volume: 22, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Aorta; Atmospheric Pressure; Benzimidazoles; Biphenyl Compounds; Captopril; Cell Line; Cell Proliferation; Colorimetry; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical; Tetrazoles; Time Factors

2008
MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides.
    American journal of physiology. Cell physiology, 2008, Volume: 295, Issue:5

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cells, Cultured; Flavonoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Okadaic Acid; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Vanadates

2008
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
    Alcoholism, clinical and experimental research, 2008, Volume: 32, Issue:11

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Disease Models, Animal; Flavonoids; Irbesartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling

2008
Regulation of ACE2 in cardiac myocytes and fibroblasts.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 295, Issue:6

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Atrial Natriuretic Factor; Butadienes; Cells, Cultured; Endothelin-1; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Heart Ventricles; Losartan; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Nitriles; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction

2008
Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Butadienes; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Male; MAP Kinase Kinase Kinases; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitriles; Nitroarginine; Nitroprusside; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Vasoconstriction; Vasodilation

2009
Telmisartan, an angiotensin II type 1 receptor antagonist, attenuates T-type Ca2+ channel expression in neonatal rat cardiomyocytes.
    European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3

    Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Benzoates; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; F-Box Proteins; Flavonoids; Gene Expression Regulation; Heart Rate; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Telmisartan; Tetrazoles; Time Factors; Valine; Valsartan; Zebrafish Proteins

2009
Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells.
    Journal of biochemistry, 2009, Volume: 146, Issue:5

    Topics: Angiotensin II; Animals; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Kruppel-Like Transcription Factors; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley

2009
Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.
    Circulation research, 2010, Mar-05, Volume: 106, Issue:4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Activation; Flavonoids; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Signal Transduction; Solitary Nucleus; Spin Labels; Time Factors

2010
Centrally administered insulin potentiates the pressor response to angiotensin II.
    Regulatory peptides, 2010, Aug-09, Volume: 163, Issue:1-3

    Topics: Angiotensin II; Animals; Blood Pressure; Flavonoids; Insulin; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley

2010
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:1

    Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells

2011
Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.
    Neuropeptides, 2011, Volume: 45, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Flavonoids; Imidazoles; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley

2011
Expression and function of osteopontin in vascular adventitial fibroblasts and pathological vascular remodeling.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Aldosterone; Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cells, Cultured; Connective Tissue; Fibroblasts; Flavonoids; Gene Expression; Immunohistochemistry; Male; Mitogen-Activated Protein Kinases; Oligodeoxyribonucleotides, Antisense; Osteopontin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factor AP-1; Vasoconstrictor Agents

2011
13-cis-Retinoic acid specific down-regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells.
    Journal of molecular endocrinology, 2012, Volume: 48, Issue:2

    Topics: Angiotensin II; Animals; Antioxidants; Aorta; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gene Expression Regulation; Glucose; Insulin; Isotretinoin; Liver; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Receptor, Angiotensin, Type 1; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Signal Transduction

2012
Apelin secretion and expression of apelin receptors in 3T3-L1 adipocytes are differentially regulated by angiotensin type 1 and type 2 receptors.
    Molecular and cellular endocrinology, 2012, Apr-04, Volume: 351, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Animals; Apelin; Apelin Receptors; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Flavonoids; Gene Expression Regulation; Imidazoles; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthyridines; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled

2012
Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
    Pharmacological research, 2012, Volume: 66, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Flavonoids; Losartan; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phosphorylation; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents

2012
AngiotensinII preconditioning promotes angiogenesis in vitro via ERKs phosphorylation.
    Journal of biomedicine & biotechnology, 2012, Volume: 2012

    Topics: Analysis of Variance; Angiogenesis Inducing Agents; Angiotensin II; Animals; Cells, Cultured; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Male; Myocardium; Neovascularization, Physiologic; Phosphorylation; Protective Agents; Rats; Rats, Wistar

2012
[Effects of Ac-SDKP on angiotensin II-induced collagen synthesis in vascular adventitial fibroblasts].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013, Volume: 29, Issue:2

    Topics: Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Collagen Type III; Fibroblasts; Flavonoids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Oligopeptides; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1

2013
Effects of cyclic stretch on the molecular regulation of myocardin in rat aortic vascular smooth muscle cells.
    Journal of biomedical science, 2013, Jul-15, Volume: 20

    Topics: Angiotensin II; Animals; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Promoter Regions, Genetic; Rats; Signal Transduction; Stress, Mechanical; Trans-Activators

2013
ERK signaling mediates enhanced angiotensin II-induced rat aortic constriction following chronic intermittent hypoxia.
    Chinese medical journal, 2013, Volume: 126, Issue:17

    Topics: Angiotensin II; Animals; Aorta; Flavonoids; Hypoxia; Male; MAP Kinase Signaling System; Phosphorylation; Rats; Rats, Wistar; Vasoconstriction

2013
Angiotensin II-derived reactive oxygen species promote angiogenesis in human late endothelial progenitor cells through heme oxygenase-1 via ERK1/2 and AKT/PI3K pathways.
    Inflammation, 2014, Volume: 37, Issue:3

    Topics: Angiotensin II; Antioxidants; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Endothelial Progenitor Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Heme Oxygenase-1; Humans; Morpholines; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering

2014
Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation.
    Journal of molecular and cellular cardiology, 2014, Volume: 66

    Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cadherins; Cell Movement; Cells, Cultured; Flavonoids; Gene Expression Regulation; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; Oxidation-Reduction; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Tetrazoles; Valine; Valsartan

2014
Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 35, Issue:2

    Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation

2015
Adipokine CTRP6 improves PPARγ activation to alleviate angiotensin II-induced hypertension and vascular endothelial dysfunction in spontaneously hypertensive rats.
    Biochemical and biophysical research communications, 2017, Jan-22, Volume: 482, Issue:4

    Topics: Adipokines; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Cell Separation; Coronary Vessels; Endothelium, Vascular; Flavonoids; Flow Cytometry; Gene Silencing; Hypertension; Male; Mitogen-Activated Protein Kinase 3; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Small Interfering; Signal Transduction

2017
Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway.
    IUBMB life, 2019, Volume: 71, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Butadienes; Cell Survival; Cycloheximide; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; Nitriles; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha

2019