angiotensin ii has been researched along with pd 123319 in 645 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 240 (37.21) | 18.2507 |
| 2000's | 279 (43.26) | 29.6817 |
| 2010's | 121 (18.76) | 24.3611 |
| 2020's | 5 (0.78) | 2.80 |
| Authors | Studies |
|---|---|
| Blankley, CJ; Chucholowski, A; Connolly, CJ; Himmelsbach, RJ; Hodges, JC; Klutchko, SR; Neergaard, SJ; Quin, J; Sebastian, A; Van Nieuwenhze, MS | 1 |
| De León, H; Garcia, R | 1 |
| Bird, IM; Magness, RR; Mason, JI; Rainey, WE | 1 |
| Chaki, S; Inagami, T | 1 |
| Achard, JM; Gardin, JP; Houillier, P; Lazar, G; Paillard, M; Poggioli, J | 1 |
| Boswell, F; Dornan, ES; Kelly, M; Lyall, F; McQueen, J | 1 |
| Damon, TH; Douglas, JG; Ernsberger, P; Zhou, J | 1 |
| Garcia, R; Gauquelin, G | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; Widdop, RE | 2 |
| Hong, JS; Hudson, PM; Mar, EC; McMillian, MK; Suh, HH | 1 |
| Kang, J; Posner, P; Sumners, C | 1 |
| Näveri, L; Saavedra, JM; Strömberg, C | 4 |
| Bjork, FA; Hodges, JC; Keiser, JA; Taylor, DG | 1 |
| Boulay, G; Escher, E; Guillemette, G; Luong, TT; Servant, G | 1 |
| Crews, FT; Gyurko, R; Kimura, B; Kurian, P; Phillips, MI | 1 |
| Byrd, EW; Carr, BR; Rainey, WE; Sinnokrot, RA | 1 |
| Bardhan, S; Inagami, T; Kambayashi, Y; Shirai, H; Takahasi, K | 1 |
| Kawahara, Y; Nakayama, I; Okuda, M; Tsuda, T; Yokoyama, M | 1 |
| Giasson, E; Meloche, S | 1 |
| Auch-Schwelk, W; Duske, E; Fleck, E; Hess, B; Hildebrandt, AG; Klein, U; Regitz-Zagrosek, V; Steffen, C | 1 |
| Smith, RD | 1 |
| Garrison, EA; Kadowitz, PJ; Osei, SY; Santiago, JA | 1 |
| Hoshijima, M; Kawahara, Y; Nakayama, I; Okuda, M; Yokoyama, M | 1 |
| Sim, MK; Yuan, HT | 1 |
| de Gasparo, M; Levens, NR | 1 |
| Ikeda, M; Kohno, M; Takeda, T | 1 |
| Ben, A; Cox, SL; Story, DF; Ziogas, J | 1 |
| Madsen, KM; Tisher, CC; Tojo, A | 1 |
| Agnati, LF; Fior, DR; Fuxe, K; Hedlund, PB; Narváez, JA; Yang, SN | 1 |
| Garcia, NH; Garvin, JL | 1 |
| Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD | 1 |
| Miyazaki, H; Murakami, K; Naruse, M; Ohnishi, J; Ozawa, Y; Sugimoto, M; Tanaka, M; Usuki, S | 1 |
| Lantelme, P; Liu, KL; Lo, M; Sassard, J | 1 |
| Cai, G; Gurdal, H; Johnson, MD; Seasholtz, TM | 1 |
| Eguchi, S; Hirata, Y; Kanno, K; Kano, H | 1 |
| Burns, KD; Harris, RC; Inagami, T | 1 |
| Bennett, T; Gardiner, SM; Widdop, RE | 1 |
| Brown, KD; Corps, AN; Hadfield, KM; Smith, RD; Vaughan, TJ | 1 |
| Cumin, F; De Gasparo, M; Levens, N; Macari, D; Whitebread, S | 1 |
| Douglas, JG; Dulin, NO; Ernsberger, P; Suciu, DJ | 1 |
| Chiu, AT; Keiser, J; Madison, AB; Nishimura, H; Patton, CM; Walker, OE | 1 |
| Fleck, E; Hildebrandt, A; Neuss, M; Regitz-Zagrosek, V | 1 |
| Imanaka, T; Mineo, C; Shimizu, H; Takada, K; Takano, T | 1 |
| Argiolas, L; Marano, G | 1 |
| Cheng, DY; Dent, EL; DeWitt, BJ; Kadowitz, PJ; Nossaman, BD | 1 |
| Haberl, RL | 1 |
| Catalioto, RM; Criscuoli, M; Mizrahi, J; Renzetti, AR; Subissi, A | 1 |
| Diamant, D; Ingelfinger, JR; Lopez, JJ; Lorell, BH; Schunkert, H; Tang, SS; Weinberg, EO | 1 |
| Blake, DR; Knock, GA; Polak, JM; Suzuki, T; Walsh, DA; Wharton, J | 1 |
| Adler-Graschinsky, E; Enero, MA; Gironacci, MM; Peña, C | 1 |
| Li, BH; Rowland, NE; Rozelle, AK; Smith, GC | 1 |
| Komorowski, J; Kunert-Radek, J; Pawlikowski, M; Stepień, H | 1 |
| Cierco, M; Israel, A | 1 |
| Becú-Villalobos, D; Díaz-Torga, GS; Lacau-Mengido, IM; Libertun, C; Thyssen, SM | 1 |
| Becú-Villalobos, D; Díaz-Torga, GS; Libertun, C | 1 |
| Linas, SL; Schelling, JR | 1 |
| Hogarty, DC; Phillips, MI; Tran, DN | 1 |
| Maita, ME; Mento, PF; Vernace, MA; Wilkes, BM | 1 |
| Grupp, LA; Harding, S | 1 |
| Honda, K; Iida-Kubota, E; Yazawa, H | 1 |
| Bottari, S; De Gasparo, M; Levens, N; Macari, D; Whitebread, S | 1 |
| Arendshorst, WJ; Chatziantoniou, C | 1 |
| Hayashi, K; Saruta, T; Suzuki, H | 1 |
| Cooney, AS; Fitzsimons, JT | 1 |
| Tanabe, N; Tsujimoto, G; Ueno, A | 1 |
| Bottari, SP; Brechler, V; de Gasparo, M; Jones, PW; Levens, NR | 1 |
| Endoh, M; Ishihata, A | 1 |
| Ferguson, AV; Li, Z | 1 |
| Cook, MD; Cook, VI; Kimura, B; Phillips, MI; Wilcox, CS | 1 |
| Naftolin, F; Nemeth, G; Pepperell, JR; Yamada, Y | 1 |
| Hollenberg, MD; Laniyonu, A; Saifeddine, M; Yang, SG | 1 |
| Fregly, MJ; Rowland, NE | 1 |
| Porter, JP; Toney, GM | 2 |
| Douglas, JG; Ernsberger, P; Hopfer, U; Ke, FC; Madhun, ZT; Zhou, J | 1 |
| Dudley, DT; Summerfelt, RM | 1 |
| Bossé, R; Boulay, G; Escher, E; Guillemette, G; Servant, G; Zhou, LM | 1 |
| Chou, L; Reid, IA; Wong, J | 1 |
| Feolde, E; Frelin, C; Vigne, P | 1 |
| Perrone, MH; Scheuer, DA | 1 |
| Carey, RM; Siragy, HM | 3 |
| Akimoto, Y; Aoki, H; Hirano, H; Karube, M; Koyama, N; Nagai, A; Nakamura, Y; Oda, T; Yoshimura, Y | 1 |
| Gorczynska, E; Handelsman, DJ; Spaliviero, J | 1 |
| Chua, BH; Chua, CC; Hamdy, RC | 3 |
| Daemen, MJ; Fingerle, J; van Kleef, EM | 1 |
| Brochu, M; Forcier, I; St-Louis, J | 1 |
| Aldred, GP; Chai, SY; MacGregor, DP; Mendelsohn, FA; Moeller, I | 1 |
| Rabkin, SW | 1 |
| Gelband, CH; Martens, JR; Posner, P; Sumners, C; Wang, D | 2 |
| Benessiano, J; Caputo, L; Duriez, M; Henrion, D; Heymes, C; Levy, BI; Poitevin, P; Samuel, JL | 1 |
| Mendelsohn, FA; Moeller, I; Reed, G; Small, DH | 1 |
| Kageyama, Y; Matsumoto, A; Murakami, M; Naitoh, M; Saruta, T; Suzuki, H; Tsujimoto, G | 1 |
| Galaverna, O; Liénard, F; Martial, FP; Meile, MJ; Mousseau, MC; Nicolaïdis, S; Thornton, SN | 1 |
| Kobayashi, T; Kuji, N; Miyazaki, T; Oda, T; Sueoka, K; Tanaka, M; Yoshimura, Y | 1 |
| Harris, PJ; Hiranyachattada, S | 1 |
| Benhaïm, A; Féral, C; Leymarie, P | 1 |
| Cox, SL; Story, DF; Ziogas, J | 2 |
| Georgiev, VP; Kambourova, TS; Lazarova, MB | 1 |
| Breault, L; Gallo-Payet, N; Lehoux, JG | 2 |
| Grochal, M; Kulig, A; Kunert-Radek, J; Mucha, S; Pawllkowski, M; Stepień, H; Zieliński, K | 1 |
| Berrino, L; D'Amico, M; di Filippo, C; Rossi, F | 1 |
| Alcorn, D; Dean, R; MacGregor, D; Mendelsohn, FA; Zhuo, J | 1 |
| Saward, L; Zahradka, P | 1 |
| Hagiwara, H; Hirose, S; Hiruma, Y; Inoue, A | 1 |
| Forster, C; le Tran, Y | 1 |
| Arendshorst, WJ; Chatziantoniou, C; Kurtz, A; Ruan, X; Wagner, C | 1 |
| Armour, JA; Horackova, M | 1 |
| Higson, JT; Tallant, EA | 1 |
| Fluharty, SJ; He, P; Hines, J; Reagan, LP; Siemens, IR; Yang, XD; Yee, DK | 1 |
| Aikawa, J; Fukazawa, M; Ishikawa, M; Moroi, M; Namiki, A; Yamaguchi, T | 1 |
| Dzau, VJ; Hayashida, W; Horiuchi, M; Yamada, T | 1 |
| Kunert-Radek, J; Pawlikowski, M | 1 |
| Anversa, P; Cheng, W; Cigola, E; Kajstura, J; Li, P; Malhotra, A; Meggs, LG | 1 |
| Ball, DL; Elliott, ME; Goodfriend, TL; Jefcoate, CR | 1 |
| Camargo, GM; Camargo, LA; do-Prado, MH; Luiz, AC; Queiróz, RC; Renzi, A; Saad, WA | 1 |
| Bendle, RD; Head, GA; Malpas, SC | 1 |
| Blair-West, JR; Denton, DA; McKinley, MJ; Weisinger, RS | 1 |
| Blair-West, JR; Denton, DA; Tarjan, E; Weisinger, RS | 1 |
| Espinosa, E; Liu, G; Lüscher, TF; Oemar, BS | 1 |
| Danser, AH; Lamers, JM; Saxena, PR; Schalekamp, MA; van Heugten, HA; van Kesteren, CA | 1 |
| Chatterjee, PK; Hawksworth, GM; McLay, JS; Mistry, SK; Weerackody, RP | 1 |
| Choy, PC; Hatch, GM; Kroeger, EA; Lee, D; Man, RY | 1 |
| Furukawa, T; Katsuragi, T; Makino, I; Niwa, M; Shibaguchi, H; Shibata, K | 1 |
| Albrecht, D; Ganten, D; Henklein, P | 1 |
| Bankir, L; Bouby, N; Corvol, P; Hus-Citharel, A; Llorens-Cortes, C; Marchetti, J | 1 |
| Blair-West, JR; Burns, P; Denton, DA; Tarjan, E; Weisinger, RS | 1 |
| Bottari, SP; Bourmeyster, N; Chambaz, EM; Defaye, G; Liakos, P | 1 |
| Baum, M; Quan, A; Quigley, R | 1 |
| de Gasparo, M; Fenoy, FJ; García-Salom, M; Madrid, MI; Tornel, J | 2 |
| Champion, HC; Kadowitz, PJ | 1 |
| Fujimori, A; Inagaki, O; Kusayama, T; Okazaki, T; Satoh, Y; Shibasaki, M; Takanashi, M; Tokioka, T; Uchida, W; Yanagisawa, I | 1 |
| Abe, I; Fujii, K; Fujishima, M; Onaka, U | 1 |
| Abe, K; Abe, M; Arima, S; Endo, Y; Ito, S; Ogawa, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H | 1 |
| Dampney, RA; Hirooka, Y; Potts, PD | 1 |
| Abe, K; Arima, S; Endo, Y; Ito, S; Omata, K; Takeuchi, K; Tsunoda, K; Yaoita, H | 1 |
| Champion, HC; Garrison, EA; Kadowitz, PJ | 1 |
| Borg, TK; Carver, W; Fu, L; Price, RL; Simpson, DG; Terracio, L; Zhao, J | 1 |
| Gohlke, P; Pees, C; Unger, T | 2 |
| Hamilton, BP; Hamlyn, JM; Laredo, J; Shah, JR | 2 |
| Li, JS; Schiffrin, EL; Touyz, RM | 1 |
| Dorman, RV; Freeman, EJ; Ruehr, ML | 1 |
| Champion, HC; Czapla, MA; Kadowitz, PJ | 1 |
| Averill, DB; Chappell, MC; Diz, DI; Ferrario, CM; Iyer, SN | 1 |
| Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H | 1 |
| Freel, RW; Hatch, M; Vaziri, ND | 2 |
| Kling, L; Lamparter, S; Pfeilschifter, J; Schrader, M; Ziegler, R | 1 |
| Goutsouliak, V; Rabkin, SW | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Iyer, SN | 1 |
| Galaverna, O; Liénard, F; Meile, MJ; Nicolaïdis, S; Thornton, SN | 1 |
| D'Amico, M; Di Filippo, C; Rossi, F; Warner, TD | 1 |
| Cox, BE; Kaiser, JR; Rosenfeld, CR; Roy, TA | 1 |
| Dittus, JJ; Gavini, N; Pulakat, L; Tadessee, AS | 1 |
| Andreis, PG; Belloni, AS; Gottardo, G; Macchi, V; Malendowicz, LK; Nussdorfer, GG | 1 |
| Gottardo, G; Macchi, V; Malendowicz, LK; Mazzocchi, G; Nussdorfer, GG | 1 |
| Endoh, M; Watanabe, A | 1 |
| Alvarez Arroyo, MV; Caramelo, C; Casado, S; Castilla, MA; González-Pacheco, FR; López Farré, A; Montón, M; Tan, D | 1 |
| Johns, EJ; Wong, PS | 1 |
| Alexander, LD; Chang, CH; Cui, XL; Douglas, JG; Jiao, H; Lapetina, EG; Torti, M | 1 |
| Allen, SP; Chester, AH; Hafizi, S; Morgan, K; Yacoub, MH | 1 |
| Häuser, W; Jöhren, O; Saavedra, JM | 1 |
| Carbini, LA; Gorelik, G; Scicli, AG | 1 |
| Allen, AM | 1 |
| Han, NL; Sim, MK | 1 |
| Jiménez, E; Montiel, M | 1 |
| Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ | 1 |
| Breitbart, H; Gur, Y; Lax, Y; Rubinstein, S; Zamir, N | 1 |
| Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Nyui, N; Tamura, K; Toya, Y; Umemura, S | 1 |
| Borland, JA; Catravas, JD; Chester, AH; Crabbe, S; Parkerson, JB; Yacoub, MH | 1 |
| Albrecht, D; von Bohlen und Halbach, O | 1 |
| Levy, BI; Marotte, F; Poitevin, P; Rappaport, L; Sabri, A; Samuel, JL | 1 |
| Guimarães, S; Moura, D; Paiva, MQ | 1 |
| Byron, KL; Govindarajan, G; Griffin, TM; Lucchesi, PA; Sabri, A; Samarel, AM | 1 |
| Fukuda, K; Izumo, S | 1 |
| Buchko, J; Lalonde, C; Nguyen, M; Saward, L; Thomas, S; Werner, J; Yau, L; Zahradka, P | 1 |
| Arai, K; Demura, H; Imaki, T; Kobayashi, M; Miyazaki, H; Naruse, K; Naruse, M; Seki, T; Tanabe, A; Yoshimoto, T | 1 |
| Hirata, K; Kanazawa, H; Yoshikawa, J | 1 |
| Daubert, DL; Meadows, GG; Sanchez, PJ; Speth, RC; Wang, JH | 1 |
| Davis, EA; Widdop, RE; Zwart, AS | 1 |
| Akishita, M; Daviet, L; Dzau, VJ; Horiuchi, M; Ito, M; Lehtonen, JY | 1 |
| Hilgers, KF; Mann, JF; Schmieder, RE; Scrogin, KE; Veelken, R | 1 |
| De Paolis, P; Gigante, B; Natale, A; Piras, O; Porcellini, A; Volpe, M | 1 |
| Audus, KL; Rose, JM | 1 |
| Ardaillou, R | 1 |
| Cui, XL; Douglas, JG; Haithcock, D; Hopfer, U; Jiao, H | 1 |
| Bivalacqua, TJ; Champion, HC; Kadowitz, PJ; Lambert, DG; McNamara, DB | 1 |
| Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ; Lambert, DG | 1 |
| Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM | 1 |
| Higaki, J; Moriguchi, K; Ogihara, T; Ohishi, M; Okamura, A; Rakugi, H; Suzuki, K; Takiuchi, S; Yanagitani, Y | 1 |
| Mendelsohn, FA; Ohishi, M; Zhuo, J | 1 |
| Endemann, D; He, G; Li, JS; Schiffrin, EL; Touyz, RM | 1 |
| Georgiev, V; Georgieva, D | 1 |
| Dhalla, NS; Saward, L; Shao, Q; Zahradka, P | 1 |
| Han, HJ; Koh, HJ; Park, SH | 1 |
| Borges, AC; Paiva, TB; Prioste, RN; Shimuta, SI | 1 |
| Barnhart, DC; Mulholland, MW; Romanchuk, G; Sarosi, GA | 1 |
| Anwar, M; Ibrahim, IN; Kadowitz, PJ; Kaye, AD; Nossaman, BD; Smith, DE | 1 |
| Fujita, T; Ishigami, T; Iwamoto, T; Kihara, M; Kobayashi, S; Toya, Y; Umemura, S; Yabana, M | 1 |
| Sharma, A; Singh, M | 1 |
| Lew, WY; Yasuda, S | 1 |
| Baum, M; Quan, A | 1 |
| Nishimura, H; Qin, ZL; Yan, HQ | 1 |
| Chevalier, RL; Thornhill, BA; Wolstenholme, JT | 1 |
| Tamaki, T; Yoshizumi, M | 1 |
| Brosius, FC; Izumo, S; Malhotra, R; Sadoshima, J | 1 |
| Deng, LY; He, G; Schiffrin, EL; Touyz, RM; Wu, XH | 1 |
| Fujinaga, M; Hein, L; Hutchinson, HG; Pratt, RE | 1 |
| Corvol, P; Gasc, JM; Hus-Citharel, A; Llorens-Cortes, C; Marchetti, J; Roques, B; Zini, S | 1 |
| Broughton Pipkin, F; Pratten, MK; Tebbs, C | 1 |
| Fujiyama, A; Fujiyama, S; Iwasaka, T; Kawada, N; Koyama, Y; Kurihara, H; Masaki, H; Matsubara, H; Miwa, T; Miyazaki, M; Mori, Y; Murasawa, S; Nakagawa, K; Nozawa, Y; Ozono, R; Shibasaki, Y; Takahashi, H; Takai, S; Tanaka, Y; Tsutsumi, Y | 1 |
| Diep, QN; Li, JS; Schiffrin, EL | 1 |
| Henrion, D; Heymes, C; Lévy, BI; Loufrani, L; Matrougui, K | 1 |
| Côté, F; Do, TH; Gallo, JM; Gallo-Payet, N; Laflamme, L | 1 |
| Cheung, PK; Saward, L; Wilson, DP; Zahradka, P | 1 |
| Coba, MP; Gironacci, MM; Peña, C | 1 |
| Briand, R; Lamouche, S; Martineau, D; Yamaguchi, N | 1 |
| Lamparter, S; Sun, Y; Weber, KT | 1 |
| Georgiev, V; Opitz, M | 1 |
| Bivalacqua, TJ; Champion, HC; Dalal, A; Kadowitz, PJ | 1 |
| Coviello, A; Peral de Bruno, M; Romano, L | 1 |
| Arendshorst, WJ; Coffman, TM; Oliverio, MI; Ruan, X | 1 |
| Kasahara, T; Kawano, H; Kimura, S; Kitamura, H; Kunieda, Y; Masuda, H; Nakagawa, K; Nakagawa, M; Nakahara, Y; Nishimura, H; Sawada, S; Sugano, T; Tsuji, H; Yano, S; Yoshizumi, M | 1 |
| Carbini, LA; Nadal, JA; Nussbaum, JJ; Scicli, AG; Scicli, GM | 1 |
| Damme, U; Daniel, WG; Garlichs, CD; Mügge, A; Plötze, K; Schmeisser, A; Zhang, H | 1 |
| Boon, WC; Moritz, KM; Wintour, EM | 1 |
| Dixon, B; Rowe, BP | 1 |
| Doerr, G; Fleck, E; Graf, K; Kappert, K; Schmidt, G; Wollert-Wulf, B | 1 |
| Cody, RJ; Goetze, S; Graf, K; Hsueh, WA; Kawano, H; Kawano, Y; Law, RE; Schnee, J | 1 |
| Clark, KE; Greenberg, SG; Lambers, DS | 1 |
| Danser, AH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schalekamp, MA | 1 |
| Arima, S; Endo, Y; Ito, O; Ito, S; Kohagura, K; Omata, K | 1 |
| De Paolis, P; Gigante, B; Giliberti, R; Lombardi, A; Porcellini, A; Rubattu, S; Savoia, C; Volpe, M | 1 |
| Gutierez, CI; Israel, A; Sosa, B | 1 |
| Chevalier, RL; Thornhill, BA; Yoo, KH | 1 |
| De Paolis, P; Gigante, B; Panina, G; Piras, O; Rubattu, S; Savoia, C; Volpe, M | 1 |
| Henrion, D; Lévy, BI; Matrougui, K | 1 |
| Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Nanmoku, T; Takekoshi, K | 1 |
| Arroyo, V; Bataller, R; Bosch, J; Garcia-Ramallo, E; Gasull, X; Ginès, P; Görbig, MN; Nicolás, JM; Rodés, J | 1 |
| Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR | 1 |
| Auger-Messier, M; Escher, E; Gosselin, MJ; Guillemette, G; Leclerc, PC; Leduc, R | 1 |
| Fliegel, L; Moor, AN; Murtazina, R | 1 |
| Cho, KW; Kim, SH; Kim, SZ; Kim, YG; Park, JK | 1 |
| Carroll, MA; Croft, KD; McGiff, JC; Sanchez-Mendoza, A | 1 |
| Howard, EF; Landon, EJ; Myers, PR; Steimle, A; Takagi, T; Tamura, M; Tanner, M | 1 |
| Alvarez, A; Esplugues, JV; Issekutz, AC; Kubes, P; O'Connor, E; Piqueras, L; Sanz, MJ | 1 |
| Min, L; Sim, MK; Xu, XG | 1 |
| Anderson, S; Mader, SL; Reed, JF; Roullet, JB; Schutzer, WE; Xue, H | 1 |
| Cao, Z; Casley, D; Cooper, ME; Cox, A; Dean, R; Forbes, JM; Gilbert, RE; Kelly, DJ; Martinello, P | 1 |
| Bader, M; Böhm, M; Bricca, G; Ganten, D; Monti, J; Schinke, M | 1 |
| Armando, I; Ciuffo, G; Egidy, G; Häuser, W; Hoe, KL; Inagami, T; Jöhren, O; Saavedra, JM; Sembonmatsu, T | 1 |
| Fujiyama, S; Higashiyama, S; Iba, O; Iwasaka, T; Jyo, N; Koyama, Y; Maruyama, K; Masaki, H; Matsubara, H; Mori, Y; Nose, A; Nozawa, Y; Ogata, N; Tateishi, E; Tsutsumi, Y; Uchiyama, Y | 1 |
| Clanachan, AS; Ford, WR; Jugdutt, BI | 1 |
| Duhault, J; Lonchampt, M; Pennel, L | 1 |
| Sandmann, S; Unger, T; Yu, M | 1 |
| Chan, JY; Chan, SH; Lin, K | 1 |
| Bloom, DC; Fang, X; Fluharty, SJ; Hines, J; Kratz, E; Maher, P; Mizukoshi, E; Moffett, J; Myers, J; Peng, H; Stachowiak, EK; Stachowiak, MK | 1 |
| Chen, Y; Dong, X; Fung, ML; Lam, SY; Leung, PS | 1 |
| Ikegami, H; Suzuki, T; Yamada, T | 1 |
| Carrier, GO; Catravas, JD; Dimitropoulou, C; Fuchs, L; White, RE; Zhang, H | 1 |
| El Mabrouk, M; He, G; Schiffrin, EL; Touyz, RM | 1 |
| Brun, SR; da Luz, V; Fernandez, M; Marino-Neto, J; Paschoalini, MA | 1 |
| Andrade, SP; Machado, RD; Santos, RA | 1 |
| Frandsen, E; Ibsen, H; Jonassen, TE; Petersen, JS; Staahltoft, D; Worck, RH | 1 |
| de Zeeuw, D; Filipeanu, CM; Henning, RH; Nelemans, A | 1 |
| Mercure, C; Reudelhuber, TL; Touyz, RM | 1 |
| Lombard, JH; Weber, DS | 1 |
| Breno, MC; Picarelli, ZP; Porto, CS | 1 |
| Ma, CT; Yu, TZ | 1 |
| Blanco, J; Egido, J; Lorenzo , O; Ruiz-Ortega, M; Rupérez, M | 1 |
| Aizman, R; Celsi, G; Chen, M; Gerasev, A; Grahnquist, L | 1 |
| Camara, AK; Osborn, J | 1 |
| Brunette, MG; Charbonneau, A; Leclerc, M | 1 |
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| Barrett, EJ; Cao, W; Carey, RM; Chai, W; Liu, J; Liu, Z; Wang, W | 1 |
| Danser, AH; Moltzer, E; van Esch, JH; van Veghel, R; Verkuil, AV | 1 |
| Anand-Srivastava, MB; Gomez Sandoval, YH; Lévesque, LO | 1 |
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| Fogo, AB; Han, JY; Kon, V; Ma, LJ; Naito, T; Tang, Y; Yang, H; Zuo, Y | 1 |
| Bi, J; Chappell, MC; Contag, SA; Rose, JC | 1 |
| Almeida, J; Barreto-Chaves, ML; Carneiro-Ramos, MS; Diniz, GP; Nadu, AP; Santos, RA; Vieira, RL | 1 |
| Chen, X; Chen, ZG; Cheng, B; Gu, YF; Liu, HW; Liu, WZ; Wu, HJ | 1 |
| Casley, D; Gaspari, TA; Tesanovic, S; Vinh, A; Widdop, RE | 1 |
| Cai, L; Chen, X; Fu, S; Sui, G; Yang, Y; Zhao, Y | 1 |
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| Carretero, OA; D'Ambrosio, MA; Garvin, JL; Ren, Y | 1 |
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| Chang, H; Che, HL; Guo, WG; Song, Z; Wang, T; Wang, YY; Xie, MJ; Yu, ZB; Zhang, L | 1 |
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| Chou, PC; Hsiao, PJ; Hsieh, TJ; Hung, WW; Lin, KD; Lin, T; Shin, SJ | 1 |
| Denton, KM; Evans, RG; Hilliard, LM; Kett, MM; Nematbakhsh, M; Sampson, AK; Teichman, E; Widdop, RE | 1 |
| Barden, A; Beilin, LJ; Croft, KD; Puddey, IB; Tsai, IJ | 1 |
| Aguilar, MI; Bosnyak, S; Clayton, D; Del Borgo, MP; Hausler, N; Jones, ES; Kirsch, JF; Perlmutter, P; Thomas, WG; Unabia, S; Welungoda, I; Widdop, RE | 1 |
| Brailoiu, E; Brailoiu, GC; Deliu, E; Motoc, D; Tica, AA | 1 |
| Louis, S; Saward, L; Zahradka, P | 1 |
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| Chen, P; Tee, WT; Than, A | 1 |
| Huang, Y; Lu, L; Ni, J; Wang, J; Wang, Z; Xue, H; Yao, T; Yu, C; Yuan, P; Zhou, L | 1 |
| Hashimoto, T; Ichiki, T; Kamiharaguchi, A; Kitamoto, S; Matsuura, H; Miyazaki, R; Sunagawa, K; Tokunou, T | 1 |
| Axelband, F; Costa-Neto, CM; Dias, J; Ferrão, FM; Lara, LS; Miranda, F; Reis, RI; Vieyra, A | 1 |
| Bell, JF; Carey, RM; Howell, NL; Kemp, BA; Navar, LG; Padia, SH; Rottkamp, DM; Shao, W | 1 |
| Arakawa, H; Kawabe, K; Sapru, HN | 1 |
| Dasgupta, C; Li, Y; Tong, W; Xiao, D; Xiong, F; Yang, S; Zhang, L | 1 |
| Denton, KM; Evans, RG; Hilliard, LM; Nematbakhsh, M; Safari, T | 1 |
| Liang, H; Sun, L; Wang, W; Xiao, W; Yang, H; Yang, Y | 1 |
| Anand-Srivastava, MB; Li, Y | 1 |
| Gao, L; Guo, J; Jiang, T; Lu, J; Wang, Y; Zhang, Y | 1 |
| Domińska, K; Lachowicz-Ochędalska, A; Ochędalski, T; Piastowska-Ciesielska, AW | 1 |
| Cao, L; Fang, Q; Li, S; Liu, Y; Mao, C; Shi, A; Wu, L; Xu, Z; Zhou, A; Zhu, H | 1 |
| Goel, R; Hanif, K; Najmi, AK; Nath, C; Pachauri, SD; Rajasekar, N; Tota, S | 1 |
| Boim, MA; Carvalho, LN; Cristovam, PC; Passos, CS | 1 |
| Alterman, M; Gallo-Payet, N; Guimond, MO; Hallberg, A; Wallinder, C | 1 |
| Iinuma, T; Kamio, N; Kawato, T; Maeno, M; Morita, T; Nakai, K; Zhao, N | 1 |
| Chen, Q; Chen, T; Wu, Y; Xiao, Q; Yan, H; Zhang, L; Zheng, X; Zhou, Y; Zhu, J; Zhu, L | 1 |
| An, SJ; Chai, XQ; Gao, WJ; Liu, P; Lu, HG; Shao, TM | 1 |
| Balìa, C; Carmazzi, Y; Celi, A; Cianchetti, S; Cordazzo, C; Lombardi, S; Neri, T; Paggiaro, P; Pedrinelli, R; Petrini, S | 1 |
| Cha, SA; Gao, S; Kang, KP; Kim, SH; Oh, YB; Park, BM | 1 |
| Gao, L; Jiang, T; Lu, J; Shi, JQ; Tan, L; Tan, MS; Yu, JT; Zhang, YD; Zhu, XC | 1 |
| Fitz, SD; Hale, MW; Hay-Schmidt, A; Johnson, PL; Lowry, CA; Sajdyk, TJ; Shekhar, A | 1 |
| Cassis, LA; Charnigo, R; Daugherty, A; Howatt, DA; Rateri, DL | 1 |
| Aoyama, M; Arai, T; Takata, Y; Watanabe, A; Yamaki, F | 1 |
| Abdulla, MH; Johns, EJ | 2 |
| Cha, SA; Gao, S; Kim, SH; Park, BH; Park, BM; Park, WH | 1 |
| Guo, QL; Song, ZB; Wu, H; Yan, JQ; Yang, Y | 1 |
| Barreto-Chaves, ML; da Silva, IB; Gomes, DA; Tavares, FM | 1 |
| Chao, J; Gao, J; Gao, L; Parbhu, KJ | 1 |
| Ishikawa, M; Kanno, S; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yaoita, F; Yomogida, S | 1 |
| Cha, SA; Gao, S; Kim, SH; Park, BM | 1 |
| Buikema, H; Faas, MM; Henning, RH; Plösch, T; van Buiten, A; van der Graaf, AM; Wiegman, MJ; Zeeman, GG | 1 |
| Liu, SS; Tang, JM; Wang, HY; Zhou, XM | 1 |
| Alzamora, R; Ayala, P; Barrientos, V; Chiong, M; Díaz-Araya, G; Escudero, N; García, L; Godoy, I; Hevia, D; Jalil, JE; Lavandero, S; Michea, L; Morales, C; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M | 1 |
| Baragatti, B; Coceani, F; Pagni, E; Scebba, F | 1 |
| Chen, P; Cui, Y; Huang, B; Jiang, T; Jiang, Y; Liang, Y; Ouyang, J; Zhou, Q | 1 |
| Beyda, RM; Nagami, GT; Plumer, AK; Schachter, O | 1 |
| Alagarsamy, S; Alexander, LD; Cui, X; Ding, Y | 1 |
| Kou, J; Wang, C; Wang, K; Zhang, Y | 1 |
| Chen, CC; Ho, LT; Hsu, YP; Juan, CC; Kwok, CF; Lin, YJ; Shih, KC | 1 |
| Brown, RD; Denton, KM; Evans, RG; Firth, LC; Hilliard, LM; Mirabito, KM; Moritz, KM; Wirth, LC | 1 |
| Akamine, EH; Aragão, DS; Carvalho, MH; Casarini, DE; Filgueira, FP; Fortes, ZB; Hagihara, GN; Lobato, NS | 1 |
| Mansoori, A; Nematbakhsh, M; Oryan, S | 2 |
| Bruce, E; Espejo, A; Francis, J; Horowitz, A; Katovich, MJ; Nair, A; Oswalt, A; Raizada, MK; Rathinasabapathy, A; Shenoy, V; Steckelings, UM; Sumners, C; Unger, T | 1 |
| Agrawal, DK; Ikhapoh, IA; Pelham, CJ | 1 |
| Furukawa, H; Hashimoto, T; Kanematsu, Y; Kitazato, KT; Kuwabara, A; Lawton, MT; Nagahiro, S; Shikata, F; Shimada, K; Tada, Y; Wada, K; Wei, Y | 1 |
| An, SJ; Fu, JQ; Jiao, Z; Li, X; Liu, P; Lu, HG; Shao, TM; Wang, ZJ | 1 |
| Casselbrant, A; Fändriks, L; Malinauskas, M; Marschall, HU; Wallenius, V | 1 |
| Jiang, X; Ning, Q; Zhang, F | 1 |
| Auteri, M; Caldara, G; Liotta, R; Mastropaolo, M; Mulè, F; Serio, R; Zizzo, MG | 1 |
| Chen, P; Li, X; Luo, J; Patterson, AJ; Xue, Q; Zhang, G | 1 |
| Smith, FG; Vinturache, AE | 1 |
| Clark, MA; Gowrisankar, YV | 1 |
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| Burghi, V; Cervino, IA; Dominici, FP; Mazziotta, L; Miquet, JG; Muñoz, MC; Quiroga, DT | 1 |
| Baptista, RFF; Chies, AB; de Lábio, RW; de Oliveira, PB; Payão, SLM; Rossignoli, PS | 1 |
| Aguiar, DC; Almeida-Santos, AF; Campagnole-Santos, MJ; Fontes, MAP; Kangussu, LM; Moreira, FA; Santos, RAS | 1 |
| Fabris, D; Fachim, HA; Genaro, K; Prado, WA | 1 |
| Bessaguet, F; Danigo, A; Demiot, C; Desmoulière, A; Magy, L; Sturtz, F | 1 |
| Cao, T; Fan, Y; Hu, B; Jia, R; Lu, Y; Luo, X; Qiao, H; Sun, B; Wang, N; Yan, J | 1 |
| Duan, XP; Gao, ZX; Gu, R; Lin, DH; Su, XT; Wang, MX; Wang, WH; Wu, P | 1 |
| Biojone, C; Casarotto, PC; Castrén, E; Diniz, CRAF; Fred, SM; Joca, SRL | 1 |
| Gu, X; Li, Y; Wang, S; Yao, Y; Yu, B; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Chen, Q; Deng, W; Karnik, SS; Si, W; Wang, QK; Xiao, Y; Xie, W; Xu, C | 1 |
| Gopalakrishnan, K; Kumar, S; Mishra, JS | 1 |
| Chae, SJ; Ihm, CG; Jeong, KH; Kang, SW; Kim, JH; Kim, JS; Kim, YG; Lee, GJ; Lee, SH; Lee, TW; Lee, YH; Moon, JY; Park, HK | 1 |
| Copits, BA; de Kloet, AD; Dussor, G; Gereau, RW; Haroutounian, S; Jain, S; Kadunganattil, S; Karlsson, P; Krause, EG; McIlvried, LA; Mickle, AD; Mohapatra, DP; Price, TJ; Ray, PR; Sheahan, TD; Shepherd, AJ; Tadinada, SM; Usachev, YM; Valtcheva, MV | 1 |
| Chen, Y; Huang, T; Lin, C; Lin, M; Su, Z; Wang, J; Yuan, W | 1 |
| Jiang, X; Li, SH; Li, ZH; Liang, JX; Liao, X; Liu, HW; Wu, F; Wu, YD; Xu, Y; Yan, JX | 1 |
| Cai, W; Cai, X; Gao, F; Huang, D; Lan, J; Shi, G; Xu, H; Zhang, Y; Zheng, F; Zhong, S | 1 |
| Crook, T; Del Carmen Fernandez-Carranco, M; Evans, A; Fleming, C; Hajji, N; Harwood, C; Lattanzio, L; Li, S; Matin, R; Merlano, M; Nigro, CL; O'Neill, K; Proby, C; Rao, B; Renziehausen, A; Sim, VR; Stebbing, J; Syed, N; Szlosarek, P; Thompson, A; Tzakos, AG; Vega-Rioja, A; Wang, H; Weir, L | 1 |
| Arce, ME; Ciuffo, GM; Correa, MM; Sánchez, SI | 1 |
| Georgiev, T; Hadzhibozheva, P; Kalfin, R; Tolekova, A | 1 |
| Lin, X; Lu, J; Shi, J; Tian, M; Wu, L; Zhang, Y | 1 |
| Chen, X; Li, P; Liu, C; Wang, L | 1 |
| Mohapatra, DP; Shepherd, AJ | 1 |
| Bellanca, A; Caldara, G; Di Carlo, M; Nuzzo, D; Serio, R; Zizzo, MG | 1 |
| Chen, X; Fan, X; Gao, Q; Han, B; Li, M; Li, X; Lu, L; Sun, M; Tang, J; Tao, J; Xu, Z; Zhang, M; Zhang, Y | 1 |
| Cui, H; Liang, H; Lv, J; Wang, H; Wang, M; Wang, S; Ye, F; Zheng, Y; Zhu, Y | 1 |
| Borges, CL; Castro, CH; Colugnati, DB; de Ávila, RI; Gava, E; Kitten, GT; Lima, EM; Macedo, LM; Pedrino, GR; Valadares, MC | 1 |
| Costa-Ferreira, W; Crestani, CC; Marchi-Coelho, C; Moreno-Santos, B | 1 |
| Ge, J; Jiang, H; Su, Y; Wang, J; Wu, J; Yu, Y; Zhang, B; Zhang, L; Zou, Y | 1 |
4 review(s) available for angiotensin ii and pd 123319
| Article | Year |
|---|---|
Pharmacology of angiotensin II receptors in the kidney.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Humans; Imidazoles; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Species Specificity; Tetrazoles; Tissue Distribution | 1994 |
Angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium; Humans; Imidazoles; Kidney; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 1999 |
[Renal microcirculation].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Humans; Imidazoles; Microcirculation; Pyridines; Renal Circulation; Vascular Resistance | 1999 |
[Regeneration of perivascular nerve and role of angiotensin receptors].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcitonin Gene-Related Peptide; Humans; Imidazoles; Losartan; Male; Mesenteric Arteries; Nerve Growth Factor; Nerve Regeneration; Neuropeptide Y; Peripheral Nerve Injuries; Peripheral Nerves; Phenol; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Stimulation, Chemical | 2010 |
4 trial(s) available for angiotensin ii and pd 123319
| Article | Year |
|---|---|
Role of angiotensin type 2 receptors in human forearm vascular responses of normal volunteers.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Cross-Over Studies; Double-Blind Method; Forearm; Humans; Imidazoles; Male; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Vascular Resistance | 2001 |
Angiotensin II type 2 receptor mediates vascular smooth muscle cell apoptosis in cystic medial degeneration associated with Marfan's syndrome.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aorta; Aortic Diseases; Apoptosis; Cell Count; Cells, Cultured; Culture Media, Serum-Free; Female; Humans; Imidazoles; Indoles; Male; Marfan Syndrome; Middle Aged; Muscle, Smooth, Vascular; Pyridines; ras Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Thiazepines; Tunica Media | 2001 |
Forearm vasodilator response to angiotensin II in elderly women receiving candesartan: role of AT(2)- receptors.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Imidazoles; Middle Aged; Pyridines; Receptor, Angiotensin, Type 1; Regional Blood Flow; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 2002 |
Intradermal angiotensin II administration attenuates the local cutaneous vasodilator heating response.
Topics: Administration, Cutaneous; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Antioxidants; Ascorbic Acid; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hot Temperature; Humans; Imidazoles; Infusions, Parenteral; Losartan; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pyridines; Receptor, Angiotensin, Type 2; Regional Blood Flow; Skin; Skin Temperature; Vasoconstrictor Agents; Vasodilation | 2008 |
637 other study(ies) available for angiotensin ii and pd 123319
| Article | Year |
|---|---|
Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Imidazoles; Losartan; Pyridines; Rabbits; Rats; Receptors, Angiotensin; Stereoisomerism; Structure-Activity Relationship; Tetrazoles | 1991 |
Angiotensin II receptor subtypes in rat renal preglomerular vessels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Kidney; Kidney Glomerulus; Losartan; Microcirculation; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1992 |
Angiotensin-II acts via the type 1 receptor to inhibit 17 alpha-hydroxylase cytochrome P450 expression in ovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cells, Cultured; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; Kinetics; Losartan; Phosphoric Diester Hydrolases; Pyridines; Receptors, Angiotensin; RNA, Messenger; Sheep; Steroid 17-alpha-Hydroxylase; Tetrazoles; Zona Fasciculata; Zona Reticularis | 1992 |
A newly found angiotensin II receptor subtype mediates cyclic GMP formation in differentiated Neuro-2A cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Binding Sites; Biphenyl Compounds; Cell Differentiation; Cyclic GMP; Imidazoles; Losartan; Neuroblastoma; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1992 |
Effects of angiotensin II and nonpeptide receptor antagonists on transduction pathways in rat proximal tubule.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cyclic AMP; Imidazoles; Inositol Phosphates; Kidney Tubules, Proximal; Losartan; Male; Osmolar Concentration; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles | 1992 |
Angiotensin II increases proto-oncogene expression and phosphoinositide turnover in vascular smooth muscle cells via the angiotensin II AT1 receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Gene Expression Regulation; Genes, fos; Imidazoles; Losartan; Muscle, Smooth, Vascular; Phosphatidylinositols; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1992 |
Angiotensin II receptor subtypes in cultured rat renal mesangial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cells, Cultured; Glomerular Mesangium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Losartan; Pertussis Toxin; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Virulence Factors, Bordetella | 1992 |
Characterization of glomerular angiotensin II receptor subtypes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Kinetics; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1992 |
Inhibition of the haemodynamic effects of angiotensin II in conscious rats by AT2-receptor antagonists given after the AT1-receptor antagonist, EXP 3174.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Pyridines; Rats; Regional Blood Flow; Tetrazoles | 1992 |
Effects of [Sar1]angiotensin II on proenkephalin gene expression and secretion of [Met5]enkephalin in bovine adrenal medullary chromaffin cells.
Topics: Adrenal Medulla; Angiotensin II; Animals; Base Sequence; Cattle; Cells, Cultured; Chromaffin System; Enkephalin, Methionine; Enkephalins; Gene Expression; Imidazoles; Intracellular Membranes; Molecular Probes; Molecular Sequence Data; Protein Precursors; Pyridines; RNA, Messenger | 1992 |
Modulation of net outward current in cultured neurons by angiotensin II: involvement of AT1 and AT2 receptors.
Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Brain Stem; Cells, Cultured; Hypothalamus; Imidazoles; Losartan; Membrane Potentials; Neurons; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1992 |
Angiotensin AT2 receptors regulate cerebral blood flow in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sodium Chloride | 1992 |
Renal hemodynamic and excretory responses to PD 123319 and losartan, nonpeptide AT1 and AT2 subtype-specific angiotensin II ligands.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Pyridines; Renal Circulation; Saralasin; Tetrazoles | 1992 |
Modulation of angiotensin II binding affinity by allosteric interaction of polyvinyl sulfate with an intracellular domain of the DuP-753-sensitive angiotensin II receptor of bovine adrenal glomerulosa.
Topics: Allosteric Regulation; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cattle; Cells, Cultured; Imidazoles; Losartan; Microsomes; Polyvinyls; Pyridines; Receptors, Angiotensin; Signal Transduction; Substrate Specificity; Tetrazoles; Zona Glomerulosa | 1992 |
Angiotensin II receptor subtypes play opposite roles in regulating phosphatidylinositol hydrolysis in rat skin slices.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Chromatography, High Pressure Liquid; Hydrolysis; Imidazoles; In Vitro Techniques; Inositol Phosphates; Kinetics; Losartan; Male; Phosphatidylinositols; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Skin; Tetrazoles | 1992 |
Angiotensin-II activation of cAMP and corticosterone production in bovine adrenocortical cells: effects of nonpeptide angiotensin-II antagonists.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cattle; Corticosterone; Cyclic AMP; Imidazoles; Losartan; Pyridines; Saralasin; Tetrazoles | 1991 |
Protein tyrosine phosphatase inhibition by angiotensin II in rat pheochromocytoma cells through type 2 receptor, AT2.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Chromatography, Affinity; Guanosine Diphosphate; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pertussis Toxin; Pheochromocytoma; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Thionucleotides; Tyrosine; Virulence Factors, Bordetella | 1994 |
Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Diglycerides; Enzyme Induction; Humans; Imidazoles; Interleukin-1; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Pyridines; Rats; Recombinant Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha | 1994 |
Role of p70 S6 protein kinase in angiotensin II-induced protein synthesis in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Imidazoles; Kinetics; Losartan; Male; Molecular Weight; Muscle, Smooth, Vascular; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Polyenes; Protein Biosynthesis; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred BN; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus; Tetrazoles; Tyrosine | 1995 |
Tissue- and subtype-specific modulation of angiotensin II receptors by chronic treatment with cyclosporin A, angiotensin-converting enzyme inhibitors and AT1 antagonists.
Topics: Administration, Oral; Adrenal Cortex; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cyclosporine; Down-Regulation; Drug Interactions; Imidazoles; Kidney; Lisinopril; Liver; Losartan; Male; Pyridines; Quinolines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Up-Regulation | 1995 |
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1995 |
Analysis of responses to angiotensin peptides in the hindquarters vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arachidonic Acid; Arginine; Blood Flow Velocity; Captopril; Cats; Dose-Response Relationship, Drug; Female; Hindlimb; Imidazoles; Male; Meclofenamic Acid; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Acid; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Pyridines; Regional Blood Flow; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Angiotensin II transduces its signal to focal adhesions via angiotensin II type 1 receptors in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Rats; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1995 |
Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Captopril; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptors, Angiotensin | 1995 |
Central administration of PD 123319 or EXP-3174 inhibits effects of angiotensin II.
Topics: Angiotensin II; Animals; Brain; Hemodynamics; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred Strains; Substance P; Tetrazoles | 1993 |
Endothelin production in cultured mesangial cells of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Cells, Cultured; Endothelins; Glomerular Mesangium; Hypertension; Imidazoles; Protein Kinase C; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Receptors, Vasopressin; Tetradecanoylphorbol Acetate | 1995 |
Evidence for the involvement of different receptor subtypes in the pre- and postjunctional actions of angiotensin II at rat sympathetic neuroeffector sites.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Electric Stimulation; Female; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Neuroeffector Junction; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Vas Deferens | 1995 |
Angiotensin II regulates H(+)-ATPase activity in rat cortical collecting duct.
Topics: Adenosine Diphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Biphenyl Compounds; Collagenases; Ethylmaleimide; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Kidney Cortex; Kidney Tubules, Collecting; Losartan; Macrolides; Proton-Translocating ATPases; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Evidence for an antagonistic angiotensin II/alpha 2-adrenoceptor interaction in the nucleus tractus solitarii.
Topics: Adrenergic alpha-Antagonists; Analysis of Variance; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Heart Rate; Imidazoles; Losartan; Male; Microinjections; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Angiotensin; Software; Solitary Nucleus; Specific Pathogen-Free Organisms; Tetrazoles | 1994 |
Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule.
Topics: Adsorption; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Peptide Fragments; Perfusion; Permeability; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Analysis of responses to ANG IV: effects of PD-123319 and DuP-753 in the pulmonary circulation of the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Hypoxia; Imidazoles; Losartan; Male; Meclofenamic Acid; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction | 1995 |
Characterization of angiotensin II receptor type 2 during differentiation and apoptosis of rat ovarian cultured granulosa cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; DNA; Female; Follicle Stimulating Hormone; Granulosa Cells; Imidazoles; Kinetics; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1995 |
Angiotensin II AT1 receptor mediated contraction of the perfused rat cerebral artery.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Arteries; Imidazoles; In Vitro Techniques; Losartan; Male; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1994 |
Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diuresis; Glomerular Filtration Rate; Imidazoles; Losartan; Male; Natriuresis; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1995 |
Age-related changes in angiotensin II-stimulated vascular contraction and inositol phosphate accumulation in Fischer 344 rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arteries; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Inositol Phosphates; Losartan; Male; Pyridines; Rats; Rats, Inbred F344; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1994 |
Effect of an AT1 receptor antagonist (CV-11974) on angiotensin II-induced cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cardiomegaly; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Tetrazoles | 1994 |
Cloning of a rabbit kidney cortex AT1 angiotensin II receptor that is present in proximal tubule epithelium.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; Blotting, Northern; Blotting, Southern; Cells, Cultured; Cloning, Molecular; DNA; Epithelial Cells; Epithelium; Imidazoles; Iodine Radioisotopes; Kidney Tubules, Proximal; Losartan; Molecular Sequence Data; Polymerase Chain Reaction; Protein Binding; Pyridines; Rabbits; Receptors, Angiotensin; Sequence Homology, Nucleic Acid; Tetrazoles; Transfection | 1993 |
Effects of angiotensin II AT1- or AT2-receptor antagonists on drinking evoked by angiotensin II or water deprivation in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drinking; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Brattleboro; Tetrazoles; Water Deprivation | 1994 |
Activation of AT1 angiotensin receptors induces DNA synthesis in a rat intestinal epithelial (RIE-1) cell line.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; Blotting, Northern; Calcium; Cell Division; Cell Line; DNA; Enzyme Activation; Hydrolysis; Imidazoles; Intestinal Mucosa; Intestines; Losartan; Molecular Sequence Data; Phosphatidylinositols; Phosphorylation; Protein Kinase C; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1994 |
Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Vascular Resistance | 1994 |
Angiotensin II AT2 receptor stimulation increases cerebrovascular resistance during hemorrhagic hypotension in rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Gas Analysis; Blood Pressure; Cerebral Cortex; Cerebral Hemorrhage; Dose-Response Relationship, Drug; Hypotension; Imidazoles; Infusions, Intravenous; Injections, Intravenous; Laser-Doppler Flowmetry; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Tetrazoles; Vascular Resistance | 1994 |
Rabbit renal epithelial angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Dose-Response Relationship, Drug; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Iodine Radioisotopes; Kidney Cortex; Kinetics; Losartan; Male; Microvilli; Oligopeptides; Pyridines; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles | 1994 |
Novel angiotensin receptor subtypes in fowl.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Blood Pressure; Cell Membrane; Chickens; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Models, Cardiovascular; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Receptors, Angiotensin; Reserpine; Tetrazoles | 1994 |
Human cardiac fibroblasts express an angiotensin receptor with unusual binding characteristics which is coupled to cellular proliferation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Fibroblasts; Heart Failure; Humans; Imidazoles; Kinetics; Losartan; Myocardium; Pyridines; Radioligand Assay; Receptors, Angiotensin; Tetrazoles | 1994 |
Angiotensin II binding activity in cultured porcine arterial endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding Sites; Biphenyl Compounds; Cells, Cultured; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Swine; Tetrazoles | 1994 |
Postjunctional regulation by angiotensin II of alpha 1-adrenoceptor-mediated pressor responses in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Heart Rate; Imidazoles; Male; Neuromuscular Junction; Nitroprusside; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sympathectomy; Synaptic Transmission; Tetrazoles; Valine; Valsartan | 1994 |
Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Peptide Fragments; Pulmonary Circulation; Pyridines; Tetrazoles; Vascular Resistance | 1994 |
Role of angiotensin receptor subtypes in the response of rabbit brain arterioles to angiotensin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Biphenyl Compounds; Brain; Cerebrovascular Circulation; Imidazoles; Losartan; Male; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Vasodilation | 1994 |
Angiotensins induce the release of prostacyclin from rabbit vas deferens: evidence for receptor heterogeneity.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Epoprostenol; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Vas Deferens | 1994 |
Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cardiomegaly; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Reference Values; Tetrazoles; Tissue Distribution | 1994 |
AT1 receptor characteristics of angiotensin analogue binding in human synovium.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Arthritis, Rheumatoid; Autoradiography; Biphenyl Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Imidazoles; Immunohistochemistry; In Vitro Techniques; Iodine Radioisotopes; Ligands; Losartan; Male; Middle Aged; Osteoarthritis; Pyridines; Receptors, Angiotensin; Synovial Fluid; Tetrazoles | 1994 |
Effects of angiotensin II and angiotensin-(1-7) on the release of [3H]norepinephrine from rat atria.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Interactions; Electric Stimulation; Female; Heart; Heart Atria; Imidazoles; Losartan; Myocardium; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles | 1994 |
Comparison of fos-like immunoreactivity induced in rat brain by central injection of angiotensin II and carbachol.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Brain; Carbachol; Imidazoles; Immunohistochemistry; Injections, Intraventricular; Losartan; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Tetrazoles | 1994 |
Stimulatory effect of angiotensin II on the proliferation of mouse spleen lymphocytes in vitro is mediated via both types of angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Imidazoles; Losartan; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Pyridines; Receptors, Angiotensin; Spleen; Tetrazoles; Thymidine | 1994 |
Role of angiotensin AT1 receptor in the cardiovascular response to footshock.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Electroshock; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1994 |
Effects of LHRH and ANG II on prolactin stimulation are mediated by hypophysial AT1 receptor subtype.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Gonadotropin-Releasing Hormone; Imidazoles; In Vitro Techniques; Losartan; Perfusion; Pituitary Gland; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1994 |
Ontogeny of angiotensin-II-induced prolactin release in vivo and in vitro in female and male rats.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Losartan; Male; Pituitary Gland; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors | 1994 |
Angiotensin II-dependent proximal tubule sodium transport requires receptor-mediated endocytosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arsenicals; Biological Transport; Cell Membrane; Cells, Cultured; Endocytosis; Imidazoles; Kidney Tubules, Proximal; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium; Sodium-Hydrogen Exchangers | 1994 |
Involvement of angiotensin receptor subtypes in osmotically induced release of vasopressin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saline Solution, Hypertonic; Tetrazoles | 1994 |
Effects of angiotensin receptor subtype inhibitors on plasma angiotensin clearance.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Losartan; Male; Metabolic Clearance Rate; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
The reduction in alcohol drinking by peripherally injected angiotensin II is selectively mediated by the AT1 receptor subtype.
Topics: Alcohol Drinking; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Drinking; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1994 |
Human aortic smooth muscle cells containing angiotensin II type 1 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Calcium; Cells, Cultured; Humans; Imidazoles; Losartan; Membranes; Muscle, Smooth, Vascular; Pyridines; Receptors, Angiotensin; Tetrazoles | 1993 |
Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Potassium; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles; Vascular Resistance | 1993 |
Angiotensin receptor sites in renal vasculature of rats developing genetic hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Blood Vessels; Hemodynamics; Hypertension; Imidazoles; Losartan; Microcirculation; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasoconstriction | 1993 |
Segmental differences in angiotensin receptor subtypes in interlobular artery of hydronephrotic rat kidneys.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Hydronephrosis; Imidazoles; In Vitro Techniques; Losartan; Male; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasoconstriction | 1993 |
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst | 1993 |
Angiotensin II receptors in the rat urinary bladder smooth muscle: type 1 subtype receptors mediate contractile responses.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Urinary Bladder | 1993 |
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1993 |
Pharmacological characteristics of the positive inotropic effect of angiotensin II in the rabbit ventricular myocardium.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bupranolol; Heart Ventricles; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Myocardium; Papillary Muscles; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Prazosin; Pyridines; Rabbits; Saralasin; Tetrazoles | 1993 |
Angiotensin II responsiveness of rat paraventricular and subfornical organ neurons in vitro.
Topics: Action Potentials; Angiotensin II; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Neurons; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Subfornical Organ; Synaptic Transmission; Tetrazoles | 1993 |
Angiotensin II receptor subtypes on adrenal adenoma in primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Humans; Hyperaldosteronism; Imidazoles; Losartan; Male; Middle Aged; Pyridines; Receptors, Angiotensin; Tetrazoles | 1993 |
The type 1 angiotensin-II receptor mediates intracellular calcium mobilization in rat luteal cells.
Topics: Adenosine Triphosphatases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Biphenyl Compounds; Calcium; Corpus Luteum; Culture Media; Dinoprost; Endoplasmic Reticulum; Female; Imidazoles; Intracellular Membranes; Losartan; Osmolar Concentration; Pyridines; Rats; Receptors, Angiotensin; Terpenes; Tetrazoles; Thapsigargin | 1993 |
Nonpeptide angiotensin AT1 and AT2 receptor ligands modulate the upper limit of cerebral blood flow autoregulation in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebrovascular Circulation; Homeostasis; Hypertension; Imidazoles; Laser-Doppler Flowmetry; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1993 |
Distinct signal transduction pathways for angiotensin-II in guinea pig gastric smooth muscle: differential blockade by indomethacin and tyrosine kinase inhibitors.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Calcium; Catechols; Cyclohexanones; Dose-Response Relationship, Drug; Epidermal Growth Factor; Genistein; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Losartan; Male; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyridines; Quinacrine; Signal Transduction; Stomach; Tetrazoles; Tyrphostins | 1993 |
Effect of nonpeptide angiotensin AT-1 and AT-2 antagonists on isoproterenol-induced renin release.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Injections, Intraventricular; Isoproterenol; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1993 |
Functional role of brain AT1 and AT2 receptors in the central angiotensin II pressor response.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Brain; Chlorisondamine; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1993 |
Signal transduction mediated by angiotensin II receptor subtypes expressed in rat renal mesangial cells.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cell Division; Cells, Cultured; Glomerular Mesangium; Imidazoles; Losartan; Oligopeptides; Protein Biosynthesis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1993 |
Regulated expression of angiotensin II (AT2) binding sites in R3T3 cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; 3T3 Cells; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bombesin; Cell Division; Fibroblast Growth Factor 2; Imidazoles; Losartan; Mice; Mitogens; Pyridines; Receptors, Angiotensin; Saralasin; Tetrazoles; Up-Regulation | 1993 |
Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor.
Topics: Adrenal Cortex; Affinity Labels; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding, Competitive; Cattle; Cells, Cultured; Female; Humans; Imidazoles; In Vitro Techniques; Myometrium; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa | 1993 |
Role of AT1 receptors in the resetting of the baroreflex control of heart rate by angiotensin II in the rabbit.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Heart; Heart Rate; Imidazoles; Losartan; Male; Pressoreceptors; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles | 1993 |
Angiotensin AT1 receptors mediate a positive inotropic effect of angiotensin II in guinea pig atria.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Losartan; Myocardial Contraction; Pyridines; Radiography; Receptors, Angiotensin; Tetrazoles | 1993 |
Functional roles of brain AT1 and AT2 receptors in the central angiotensin II pressor response in conscious young spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Disease Models, Animal; Heart Rate; Hypertension; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Vasopressins | 1993 |
Angiotensin type 2 receptors mediate depressor phase of biphasic pressure response to angiotensin.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin; Tetrazoles | 1993 |
The subtype-2 (AT2) angiotensin receptor regulates renal cyclic guanosine 3', 5'-monophosphate and AT1 receptor-mediated prostaglandin E2 production in conscious rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Cyclic AMP; Dinoprostone; Extracellular Space; Female; Imidazoles; Kidney; Kinetics; Losartan; Microdialysis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reference Values; Sodium, Dietary; Tetrazoles; Time Factors | 1996 |
Angiotensin II induces ovulation and oocyte maturation in rabbit ovaries via the AT2 receptor subtype.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Cellular Senescence; Female; Imidazoles; Oocytes; Ovary; Ovulation Induction; Pyridines; Rabbits; Receptors, Angiotensin; Saralasin; Tetrazoles | 1996 |
Cyclic adenosine 3',5'-monophosphate-independent regulation of cytosolic calcium in Sertoli cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cyclic AMP; Cytosol; Dinoprost; Enzyme Inhibitors; Imidazoles; Isoquinolines; Kinetics; Losartan; Male; Protein Kinase C; Pyridines; Rats; Rats, Wistar; Sertoli Cells; Sulfonamides; Terpenes; Tetrazoles; Thapsigargin; Vasopressins | 1996 |
Angiotensin II induces TIMP-1 production in rat heart endothelial cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Cells, Cultured; Culture Media, Conditioned; Endothelium; Enzyme Inhibitors; Glycoproteins; Imidazoles; Losartan; Myocardium; Protease Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Tetrazoles; Tissue Inhibitor of Metalloproteinases; Up-Regulation; Vasoconstrictor Agents | 1996 |
Angiotensin II-induced progression of neointimal thickening in the balloon-injured rat carotid artery is AT1 receptor mediated.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Carotid Arteries; Carotid Artery Diseases; Catheterization; DNA; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1996 |
Angiotensin II receptor subtypes in the adrenals of pregnant rats.
Topics: Adrenal Glands; Adrenal Medulla; Angiotensin II; Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Female; Humans; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Zona Glomerulosa | 1995 |
Localization and quantitation of angiotensin AT1 and AT2 receptors in the pregnant and non-pregnant sheep uterus.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Anestrus; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Biphenyl Compounds; Fallopian Tubes; Female; Imidazoles; Losartan; Muscle, Smooth; Ovary; Pregnancy; Pregnancy, Animal; Pyridines; Radioligand Assay; Receptors, Angiotensin; Sheep; Tetrazoles; Uterus | 1996 |
The angiotensin II subtype 2 (AT2) receptor is linked to protein kinase C but not cAMP-dependent pathways in the cardiomyocyte.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Biphenyl Compounds; Chick Embryo; Cyclic AMP; Enzyme Activation; Heart; Imidazoles; Isoproterenol; Losartan; Myocardium; Protein Kinase C; Pyridines; Receptors, Adrenergic, beta; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Vasoconstrictor Agents | 1996 |
Angiotensin II regulation of intracellular calcium in astroglia cultured from rat hypothalamus and brainstem.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Astrocytes; Biphenyl Compounds; Brain Stem; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gadolinium; Hypothalamus; Imidazoles; Indoles; Losartan; Nifedipine; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Ryanodine; Terpenes; Tetrazoles; Thapsigargin; Time Factors | 1996 |
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles | 1996 |
Angiotensin II type 2 receptor-mediated regulation of rat neuronal K+ channels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Imidazoles; Kinetics; Losartan; Neurons; Oligopeptides; Patch-Clamp Techniques; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
A novel action of angiotensin peptides in inhibiting neurite outgrowth from isolated chick sympathetic neurons in culture.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; Chick Embryo; Imidazoles; Neurites; Neuropeptides; Pyridines; Sympathetic Nervous System; Tissue Fixation | 1996 |
Blockade of the renin-angiotensin system in heart failure in conscious dogs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Biphenyl Compounds; Captopril; Dogs; Heart Failure; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Pyridines; Reference Values; Renin-Angiotensin System; Tetrazoles | 1995 |
Effects of DOCA pretreatment on neuronal sensitivity and cell responsiveness to angiotensin II, in the bed nucleus of the stria terminalis in the rat.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Desoxycorticosterone; Electrophysiology; Imidazoles; Iontophoresis; Losartan; Male; Pyridines; Rats; Rats, Wistar; Sensitivity and Specificity; Tetrazoles; Thalamic Nuclei | 1996 |
Involvement of angiotensin II in the process of gonadotropin-induced ovulation in rabbits.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Membrane; Chorionic Gonadotropin; Dinoprost; Dinoprostone; Female; Granulosa Cells; Imidazoles; Iodine Radioisotopes; Ovulation Induction; Pyridines; Rabbits; Saralasin | 1996 |
Modulation by locally produced luminal angiotensin II of proximal tubular sodium reabsorption via an AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Kidney Tubules, Proximal; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium; Tetrazoles | 1996 |
Angiotensin II receptor type 1 on granulosa and thecal cells of rabbit preovulatory follicles.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Cells, Cultured; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Granulosa Cells; Imidazoles; Kinetics; Losartan; Pyridines; Rabbits; Receptors, Angiotensin; Saralasin; Tetrazoles; Theca Cells; Up-Regulation | 1996 |
Angiotensin II receptors involved in the enhancement of noradrenergic transmission in the caudal artery of the spontaneously hypertensive rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Losartan; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1996 |
Multiple prejunctional actions of angiotensin II on noradrenergic transmission in the caudal artery of the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction | 1996 |
Effects of non-peptide angiotensin II-receptor antagonists on pentylenetetrazol kindling in mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anticonvulsants; Biphenyl Compounds; Convulsants; Drug Evaluation, Preclinical; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Mice; Pentylenetetrazole; Pyridines; Seizures; Tetrazoles | 1996 |
The angiotensin AT2 receptor is present in the human fetal adrenal gland throughout the second trimester of gestation.
Topics: Adrenal Glands; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Female; Fetus; Gestational Age; Humans; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1996 |
The effect of angiotensin II receptor antagonists on diethylstilbestrol-induced vascular changes in the rat anterior pituitary gland: a quantitative evaluation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Diethylstilbestrol; Drug Implants; Imidazoles; Losartan; Male; Microcirculation; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Inbred F344; Silicone Elastomers; Tetrazoles | 1996 |
Angiotensin II, via an action at AT1 receptors, may modulate the behavioural effects of ET-1 in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Biphenyl Compounds; Drug Synergism; Endothelin-1; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
Angiotensin II receptors in the human adrenal gland.
Topics: Adrenal Glands; Adult; Aging; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Gestational Age; Humans; Imidazoles; Losartan; Middle Aged; Pyridines; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1996 |
Presence of angiotensin II AT2 receptor binding sites in the adventitia of human kidney vasculature.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Autoradiography; Binding, Competitive; Biphenyl Compounds; Carcinoma, Renal Cell; Humans; Imidazoles; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Losartan; Pyridines; Tetrazoles; Tunica Media | 1996 |
The angiotensin type 2 receptor mediates RNA synthesis in A10 vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Division; Cell Line; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA; Signal Transduction; Tetrazoles | 1996 |
Angiotensin II stimulates the proliferation of osteoblast-rich populations of cells from rat calvariae.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Humans; Imidazoles; Inositol 1,4,5-Trisphosphate; Kinetics; Losartan; Osteoblasts; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Skull; Tetrazoles | 1997 |
Effect of angiotensin receptor blockade in the rabbit aorta: influence of the endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Enalapril; Endothelium, Vascular; Imidazoles; Losartan; Male; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles | 1996 |
Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cloning, Molecular; Culture Techniques; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enalaprilat; Gene Expression Regulation; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Artery; Renal Circulation; Ribonucleases; RNA, Messenger; Sodium, Dietary; Tetrazoles; Vasoconstrictor Agents | 1997 |
ANG II modifies cardiomyocyte function via extracardiac and intracardiac neurons: in situ and in vitro studies.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cells, Cultured; Coculture Techniques; Coronary Circulation; Dogs; Female; Ganglia, Sympathetic; Guinea Pigs; Heart; Heart Ventricles; Imidazoles; Losartan; Male; Myocardial Contraction; Neurons; Pyridines; Stellate Ganglion; Tetrazoles; Timolol | 1997 |
Angiotensin II activates distinct signal transduction pathways in astrocytes isolated from neonatal rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Bradykinin; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Epoprostenol; Humans; Hypothalamus; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol Diacylglycerol-Lyase; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Type C Phospholipases | 1997 |
Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cloning, Molecular; COS Cells; Dithiothreitol; DNA, Complementary; Imidazoles; Locus Coeruleus; Losartan; Mice; Neuroblastoma; Oligopeptides; Olivary Nucleus; Polymerase Chain Reaction; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Tumor Cells, Cultured | 1997 |
Stimulation of angiotensin subtype 2 receptor reduces basal cGMP levels in the neointima of rat aorta after balloon injury.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Biphenyl Compounds; Catheterization; Cyclic AMP; Cyclic GMP; Imidazoles; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Tunica Intima | 1997 |
Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis.
Topics: 3T3 Cells; Angiotensin II; Animals; Apoptosis; Binding Sites; Culture Media, Serum-Free; DNA Primers; DNA-Binding Proteins; Imidazoles; Interferon Regulatory Factor-1; Interferon Regulatory Factor-2; Kinetics; Mice; Oligonucleotides, Antisense; Phosphoproteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Repressor Proteins; Time Factors; Transcription Factors; Transfection; Up-Regulation | 1997 |
Angiotensin IV stimulates the proliferation of rat anterior pituitary cells in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Division; Cells, Cultured; Imidazoles; Losartan; Male; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Wistar; Tetrazoles; Thymidine | 1997 |
Angiotensin II induces apoptosis of adult ventricular myocytes in vitro.
Topics: Alkaloids; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apoptosis; Benzophenanthridines; Biphenyl Compounds; Calcimycin; Calcium; Cells, Cultured; Chelating Agents; Cytosol; Egtazic Acid; Enzyme Inhibitors; Imidazoles; Ionophores; Isoenzymes; Losartan; Myocardium; Phenanthridines; Protein Kinase C; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1997 |
Angiotensin-responsive adrenal glomerulosa cell proteins: characterization by protease mapping, species comparison, and specific angiotensin receptor antagonists.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bucladesine; Cattle; Cells, Cultured; Chymotrypsin; Imidazoles; Losartan; Male; Methionine; Peptide Mapping; Protein Biosynthesis; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Species Specificity; Sulfur Radioisotopes; Tetrazoles; Zona Glomerulosa | 1997 |
Paraventricular nucleus administration of DuP753 or PD123319 inhibits the effects of angiotensin on water and sodium intake.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Drinking; Imidazoles; Losartan; Male; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Tetrazoles | 1996 |
The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Female; Imidazoles; Indazoles; Kidney; Losartan; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Sodium; Tetrazoles | 1997 |
Regulation of thrombospondin-1 production by angiotensin II in rat heart endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blotting, Northern; Cell Line; Cycloheximide; Dactinomycin; Endothelium; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Losartan; Membrane Glycoproteins; Myocardium; Protein Kinase C; Pyridines; Rats; Tetrazoles; Thrombospondins | 1997 |
Role of endogenous angiotensin II on sympathetic reflexes in conscious rabbits.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Biphenyl Compounds; Blood Pressure; Cardiovascular System; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypoxia; Imidazoles; Kidney; Losartan; Male; Nasopharynx; Pyridines; Rabbits; Reflex; Sympathetic Nervous System; Tetrazoles | 1997 |
Central infusion of the AT1 receptor antagonist losartan inhibits thirst but not sodium appetite in cattle.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Behavior, Animal; Biphenyl Compounds; Brain; Cattle; Cerebrospinal Fluid; Dehydration; Drinking; Female; Hypertonic Solutions; Imidazoles; Injections, Intraventricular; Losartan; Pyridines; Sodium; Tetrazoles; Thirst; Water Deprivation | 1997 |
Role of brain angiotensin II in thirst and sodium appetite of sheep.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Brain; Cerebral Ventricles; Dehydration; Diet, Sodium-Restricted; Diuresis; Female; Imidazoles; Infusions, Parenteral; Losartan; Mannitol; Naphthyridines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Saliva; Sheep; Sodium, Dietary; Tetrazoles; Thirst | 1997 |
Bimodal effects of angiotensin II on migration of human and rat smooth muscle cells. Direct stimulation and indirect inhibition via transforming growth factor-beta 1.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Movement; Gene Expression; Humans; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1997 |
Angiotensin II-mediated growth and antigrowth effects in cultured neonatal rat cardiac myocytes and fibroblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cells, Cultured; Endothelin-1; Fibroblasts; Growth Inhibitors; Growth Substances; Heart; Imidazoles; Inositol Phosphates; Losartan; Myocardium; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin | 1997 |
Selective antagonism of the AT1 receptor inhibits angiotensin II stimulated DNA and protein synthesis in primary cultures of human proximal tubular cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cells, Cultured; DNA; Humans; Imidazoles; Kidney Tubules, Proximal; Losartan; Protein Biosynthesis; Pyridines; Tetrazoles | 1997 |
On the mechanism of the losartan-mediated inhibition of phosphatidylcholine biosynthesis in H9c2 cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cell Line; Cell Membrane; Choline; Cytosol; Imidazoles; Immunoblotting; Kinetics; Losartan; Phosphatidylcholines; Pyridines; Tetrazoles; Tritium | 1997 |
Up-regulation of angiotensin type 2 receptor mRNA by angiotensin II in rat cortical cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Imidazoles; Neurons; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Up-Regulation | 1997 |
Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Disease Models, Animal; Electroencephalography; Hypertension; Imidazoles; Lisinopril; Losartan; Male; Neurons, Afferent; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thalamus; Vasoconstrictor Agents | 1997 |
Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium Channels; Culture Techniques; Imidazoles; Losartan; Male; Nephrons; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger | 1997 |
Role of brain angiotensin in thirst and sodium appetite of rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Brain; Drinking; Eating; Furosemide; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Sodium, Dietary; Thirst | 1997 |
ANG II AT1 and AT2 receptors both inhibit bFGF-induced proliferation of bovine adrenocortical cells.
Topics: Adrenal Cortex; Angiotensin II; Animals; Cattle; Cell Cycle; Cell Division; Cells, Cultured; Cyclin D1; Dinoprostone; Fibroblast Growth Factor 2; G1 Phase; Imidazoles; Indomethacin; Oligopeptides; Prostaglandin D2; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
Effect of luminal angiotensin II on rabbit proximal convoluted tubule bicarbonate absorption.
Topics: Absorption; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bicarbonates; Biological Transport; Enalaprilat; Female; Imidazoles; Kidney Tubules, Proximal; Losartan; Pyridines; Rabbits | 1997 |
Interactions between nitric oxide and angiotensin II on renal cortical and papillary blood flow.
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Imidazoles; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rats; Rats, Wistar; Regional Blood Flow; Tetrazoles; Valine; Valsartan | 1997 |
Analysis of the effects of candesartan in the mesenteric vascular bed of the cat.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Vessels; Cats; Female; Imidazoles; Male; Perfusion; Pressure; Pyridines; Splanchnic Circulation; Tetrazoles | 1997 |
Pharmacological profile of YM358, a novel nonpeptide angiotensin AT1 receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Cattle; Decerebrate State; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1997 |
Effect of interactions between nitric oxide and angiotensin II on pressure diuresis and natriuresis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Diuresis; Glomerular Filtration Rate; Imidazoles; Kidney; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pressure; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Renal Circulation; Tetrazoles; Valine; Valsartan | 1997 |
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents | 1997 |
Possible role of P-450 metabolite of arachidonic acid in vasodilator mechanism of angiotensin II type 2 receptor in the isolated microperfused rabbit afferent arteriole.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Arterioles; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Large-Conductance Calcium-Activated Potassium Channels; Male; Norepinephrine; Perfusion; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetraethylammonium; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Role of angiotensin II receptor subtypes in mediating the sympathoexcitatory effects of exogenous and endogenous angiotensin peptides in the rostral ventrolateral medulla of the rabbit.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Denervation; Female; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Pressoreceptors; Pyridines; Rabbits; Receptors, Angiotensin; Sympathetic Nervous System | 1997 |
Function of angiotensin II type 2 receptor in the postglomerular efferent arteriole.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Benzimidazoles; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Male; Microcirculation; Norepinephrine; Pyridines; Rabbits; Receptors, Angiotensin; Renal Circulation; Tetrazoles; Vasodilation | 1997 |
[Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cats; Female; Hindlimb; Imidazoles; Male; Norepinephrine; Pyridines; Receptors, Angiotensin; Tetrazoles; Time Factors; Vasoconstrictor Agents | 1997 |
The effects of angiotensin II and specific angiotensin receptor blockers on embryonic cardiac development and looping patterns.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Fetal Heart; Fibroblasts; Heart Ventricles; Hypertrophy; Imidazoles; Losartan; Morphogenesis; Myocardium; Myosin Heavy Chains; Organ Culture Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values | 1998 |
Different signaling pathways mediate stimulated secretions of endogenous ouabain and aldosterone from bovine adrenocortical cells.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Factors; Bucladesine; Cardenolides; Cattle; Cells, Cultured; Digoxin; Enzyme Inhibitors; Imidazoles; Ouabain; Pyridines; Receptor, Angiotensin, Type 2; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Zona Glomerulosa | 1998 |
Effects of AT1 and AT2 angiotensin receptor antagonists in angiotensin II-infused rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arteries; Blood Pressure; Body Weight; Coronary Vessels; Femoral Artery; Heart; Imidazoles; Infusions, Parenteral; Kidney; Losartan; Organ Size; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
ANG II-induced translocation of cytosolic PLA2 to the nucleus in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Arachidonic Acid; Calcium; Cell Nucleus; Cells, Cultured; Cytosol; Egtazic Acid; Estrenes; Imidazoles; Kinetics; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phospholipases A; Phospholipases A2; Pyridines; Pyrrolidinones; Rats | 1998 |
Responses to angiotensin peptides are mediated by AT1 receptors in the rat.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Hindlimb; Imidazoles; Losartan; Male; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 1998 |
Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Immunoglobulin G; Lisinopril; Losartan; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Vasodilation | 1998 |
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote | 1998 |
Local upregulation of colonic angiotensin II receptors enhances potassium excretion in chronic renal failure.
Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Colon; Imidazoles; Kidney Failure, Chronic; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Rubidium Radioisotopes; Up-Regulation | 1998 |
Effects of angiotensin II on bone cells in vitro.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Binding, Competitive; Cell Division; Cells, Cultured; Collagen; DNA; Femur Head; Fetus; Humans; Imidazoles; Losartan; Osteoblasts; Osteoclasts; Parathyroid Hormone; Pyridines; Rats; Skull; Vasoconstrictor Agents | 1998 |
Comparison of angiotensin II type-1 and type-2 receptor antagonists on angiotensin II-induced IP3 generation in cardiomyocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Chick Embryo; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Losartan; Myocardium; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 1998 |
Role of AT1 and AT2 receptors in the plasma clearance of angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Half-Life; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin | 1998 |
Acute sodium depletion modifies septo-preoptic neuron sensitivities to neurohormones.
Topics: Aldosterone; Angiotensin II; Angiotensins; Animals; Imidazoles; Losartan; Male; Neurons; Preoptic Area; Pyridines; Rats; Rats, Wistar; Septum Pellucidum; Sodium | 1998 |
Role of AT2 receptors in the cardiovascular events following microinjection of angiotensin II into the superior colliculus of anaesthetised rats.
Topics: Anesthesia, General; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Microinjections; Microspheres; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Regional Blood Flow; Superior Colliculi | 1998 |
Differential development of umbilical and systemic arteries. I. ANG II receptor subtype expression.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cell Membrane; Dose-Response Relationship, Drug; Femoral Artery; Heart Rate; Imidazoles; Muscle, Smooth, Vascular; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Sheep; Tetrazoles; Umbilical Arteries | 1998 |
Upregulation of vascular endothelial growth factor by angiotensin II in rat heart endothelial cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Cattle; Culture Media, Conditioned; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Immunoblotting; Losartan; Lymphokines; Nucleic Acid Synthesis Inhibitors; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rats; RNA, Messenger; Transcription Factors; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents | 1998 |
Role of Lys215 located in the fifth transmembrane domain of the AT2 receptor in ligand-receptor interaction.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Amino Acid Sequence; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligopeptides; Protein Conformation; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins | 1998 |
Distribution and functional significance of angiotensin-II AT1- and AT2-receptor subtypes in the rat adrenal gland.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
The AT2 receptor-mediated stimulation of adrenal catecholamine release may potentiate the AT1 receptor-mediated aldosterone secretagogue action of angiotensin-II in rats.
Topics: Adrenal Glands; Aldosterone; Alprenolol; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Catecholamines; Cells, Cultured; Chromaffin Cells; Culture Techniques; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Zona Glomerulosa | 1998 |
Relationship between the increase in Ca2+ transient and contractile force induced by angiotensin II in aequorin-loaded rabbit ventricular myocardium.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aequorin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bupranolol; Calcium; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Microinjections; Myocardial Contraction; Myocardium; Prazosin; Pyridines; Rabbits; Stimulation, Chemical | 1998 |
Effects of angiotensin II on endothelial cell growth: role of AT-1 and AT-2 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Cattle; Cell Count; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Receptors, Angiotensin | 1998 |
The receptor subtype mediating the action of angiotensin II on intracellular sodium in rat proximal tubules.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Extracellular Space; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium | 1998 |
Arachidonic acid mediates angiotensin II effects on p21ras in renal proximal tubular cells via the tyrosine kinase-Shc-Grb2-Sos pathway.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Arachidonic Acid; Cells, Cultured; Enzyme Inhibitors; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Guanosine Diphosphate; Guanosine Triphosphate; Imidazoles; Kidney Tubules, Proximal; Phospholipases A; Phospholipases A2; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); Pyridines; Quinacrine; Rabbits; ras Guanine Nucleotide Exchange Factors; Shc Signaling Adaptor Proteins | 1998 |
Growth response of human coronary smooth muscle cells to angiotensin II and influence of angiotensin AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Calcium; Cell Division; Cells, Cultured; Coronary Vessels; DNA; Humans; Imidazoles; Immunohistochemistry; Losartan; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Protein Biosynthesis; Pyridines; Receptors, Angiotensin; Vasoconstrictor Agents | 1998 |
Characterization and distribution of angiotensin II receptor subtypes in the mouse brain.
Topics: Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Caudate Nucleus; Imidazoles; In Vitro Techniques; Kinetics; Ligands; Locus Coeruleus; Losartan; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin | 1998 |
Angiotensin 1-7 induces bradykinin-mediated relaxation in porcine coronary artery.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Vessels; Imidazoles; In Vitro Techniques; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Swine; Vasodilation | 1998 |
Angiotensin AT1 receptor-mediated excitation of rat carotid body chemoreceptor afferent activity.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Carotid Body; Electric Stimulation; Electrophysiology; Imidazoles; Iodine Radioisotopes; Ligands; Losartan; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats.
Topics: Angiotensin II; Animals; Binding, Competitive; Hypertension; Hypothalamus; Imidazoles; Kinetics; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Species Specificity | 1998 |
Characterization of angiotensin II receptors (binding and mRNA) in the rat thyroid gland.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; DNA Primers; Imidazoles; Kinetics; Losartan; Male; Polymerase Chain Reaction; Pyridines; Rabbits; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Thyroid Gland | 1998 |
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water | 1998 |
Angiotensin II induces acrosomal exocytosis in bovine spermatozoa.
Topics: Acrosin; Acrosome; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Calcimycin; Cattle; Exocytosis; Female; Humans; Imidazoles; Losartan; Male; Pyridines; Receptors, Angiotensin; Sperm Capacitation; Sperm-Ovum Interactions | 1998 |
Activation of angiotensinogen gene in cardiac myocytes by angiotensin II and mechanical stretch.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dactinomycin; Gene Expression Regulation; Heart; Heart Ventricles; Imidazoles; Liver; Lung; Myocardium; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Fusion Proteins; RNA, Messenger; RNA, Ribosomal, 18S; Stress, Mechanical; Tetrazoles; Transcription, Genetic; Transfection | 1998 |
Differential action of angiotensin II and activity of angiotensin-converting enzyme in human bypass grafts.
Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Middle Aged; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saphenous Vein; Thoracic Arteries; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Angiotensin II inhibits long-term potentiation within the lateral nucleus of the amygdala through AT1 receptors.
Topics: Amygdala; Angiotensin II; Animals; Electrophysiology; Female; Imidazoles; Long-Term Potentiation; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
Losartan antagonism of angiotensin-II-induced potassium secretion across rat colon.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Colon; Dose-Response Relationship, Drug; Drug Antagonism; Extracellular Space; Hydrolysis; Imidazoles; In Vitro Techniques; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes; Tetrazoles | 1998 |
Microvasculature in angiotensin II-dependent cardiac hypertrophy in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterioles; Capillaries; Hypertension; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Vasoconstrictor Agents | 1998 |
Different receptors for angiotensin II at pre- and postjunctional level of the canine mesenteric and pulmonary arteries.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dogs; Female; Imidazoles; Losartan; Male; Mesenteric Arteries; Neuroeffector Junction; Pulmonary Artery; Pyridines; Receptors, Angiotensin; Saralasin | 1998 |
Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle.
Topics: Actins; Angiotensin II; Animals; Anti-Arrhythmia Agents; Aorta; Calcium; Cell Adhesion Molecules; Cells, Cultured; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Insulin; Receptors, Angiotensin; src-Family Kinases; Tyrosine | 1998 |
Angiotensin II potentiates DNA synthesis in AT-1 transformed cardiomyocytes.
Topics: Angiotensin II; Animals; Antigens, Polyomavirus Transforming; Cell Cycle; Cell Division; Cell Line, Transformed; Cyclin B; Cyclin B1; Cyclins; DNA Replication; Gene Expression Regulation; Imidazoles; Losartan; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Myocardium; Phosphorylation; Protamine Kinase; Pyridines; Simian virus 40; Thymidine; Tumor Cells, Cultured | 1998 |
Modulation of the vascular smooth muscle angiotensin subtype 2 (AT2) receptor by angiotensin II.
Topics: Angiotensin II; Animals; Antibody Specificity; Cells, Cultured; COS Cells; DNA, Complementary; Glycosylation; Imidazoles; Losartan; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Transfection | 1998 |
Angiotensin II stimulates both aldosterone secretion and DNA synthesis via type 1 but not type 2 receptors in bovine adrenocortical cells.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Cells, Cultured; DNA; Imidazoles; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa | 1998 |
Guinea pig airway hyperresponsiveness induced by blockade of the angiotensin II type 1 receptor. Role for endogenous nitric oxide.
Topics: Acetylcholine; Airway Obstruction; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bronchi; Bronchial Hyperreactivity; Bronchoconstriction; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Guinea Pigs; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines | 1999 |
Changes in angiotensin II receptors in dopamine-rich regions of the mouse brain with age and ethanol consumption.
Topics: Aging; Angiotensin II; Animals; Autoradiography; Brain; Caudate Nucleus; Dopamine; Ethanol; Female; Globus Pallidus; Imidazoles; Iodine Radioisotopes; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Protein Binding; Putamen; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors.
Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction | 1998 |
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Culture Media; DNA; Female; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; Losartan; Mice; Mice, Knockout; Muscle Development; Muscle, Smooth, Vascular; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Binding; Pyridines; Receptors, Angiotensin; Vanadates | 1999 |
Endogenous angiotensin II and the reflex response to stimulation of cardiopulmonary serotonin 5HT3 receptors.
Topics: Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Biguanides; Blood Pressure; Heart Rate; Imidazoles; Infusions, Intravenous; Kidney; Lisinopril; Male; Naphthyridines; Pressoreceptors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Receptor Agonists; Sodium Chloride; Sympathetic Nervous System | 1998 |
Role of the angiotensin II AT2-subtype receptors in the blood pressure-lowering effect of losartan in salt-restricted rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Diet, Sodium-Restricted; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 1998 |
AT1 receptors mediate angiotensin II uptake and transport by bovine brain microvessel endothelial cells in primary culture.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Biological Transport; Blood-Brain Barrier; Brain; Capillaries; Cattle; Cell Membrane Permeability; Cells, Cultured; Endothelium, Vascular; Imidazoles; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Renal proximal tubular AT2 receptor: signaling and transport.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Proteins; Imidazoles; Kidney Tubules, Proximal; Mice; Oligopeptides; Phospholipases A; Phospholipases A2; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sodium Bicarbonate | 1999 |
The influence of candesartan and PD123319 on responses to angiotensin II in the hindquarters vascular bed of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium Channel Agonists; Dose-Response Relationship, Drug; Female; Hemodynamics; Hindlimb; Imidazoles; Injections, Intravenous; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents | 1999 |
Effects of candesartan and PD123319 on responses to angiotensin II in the anesthetized mouse.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Epinephrine; Imidazoles; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
Compartmentalization of extracellular cGMP determines absorptive or secretory responses in the rat jejunum.
Topics: Angiotensin II; Animals; Arginine; Chlorides; Cyclic GMP; Diet, Sodium-Restricted; Enterotoxins; Imidazoles; Intestinal Absorption; Jejunum; Male; Microscopy, Fluorescence; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium; Water | 1999 |
Angiotensin II type 1 receptor-mediated peroxide production in human macrophages.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Humans; Imidazoles; Kinetics; Leukemia, Monocytic, Acute; Macrophages; Oxidative Stress; Peroxides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Cells, Cultured | 1999 |
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Blood Pressure; Heart Rate; Hemodynamics; Homozygote; Hypertension; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Renin | 1999 |
Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Mesenteric Artery, Superior; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction | 1999 |
Effects of angiotensin II on sodium potassium pumps, endogenous ouabain, and aldosterone in bovine zona glomerulosa cells.
Topics: Aldosterone; Angiotensin II; Animals; Cattle; Cells, Cultured; Digoxin; Imidazoles; Kinetics; Ouabain; Pyridines; Rubidium; Sodium-Potassium-Exchanging ATPase; Zona Glomerulosa | 1999 |
The role of angiotensin II and of its receptor subtypes in the acetic acid-induced abdominal constriction test.
Topics: Acetic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Colic; Imidazoles; Losartan; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Pyridines; Receptors, Angiotensin; Saralasin | 1999 |
Ca2+ mobilization in adult rat cardiomyocytes by angiotensin type 1 and 2 receptors.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Cells, Cultured; Heart; Imidazoles; Kinetics; Losartan; Male; Myocardial Contraction; Myocardium; Potassium Chloride; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors | 1998 |
A signaling pathway for stimulation of Na+ uptake induced by angiotensin II in primary cultured rabbit renal proximal tubule cells.
Topics: Amiloride; Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Cyclic AMP; Diuretics; Imidazoles; Kidney Tubules, Proximal; Losartan; Male; Protein Kinase C; Pyridines; Rabbits; Receptors, Angiotensin; Signal Transduction; Sodium; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Different pathways for Ca2+ mobilization by angiotensin II and carbachol in the circular muscle of the guinea-pig ileum.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; Carbachol; Electric Stimulation; Female; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; Isradipine; Losartan; Male; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Nickel; Nifedipine; Potassium Chloride; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Vasoconstrictor Agents; Verapamil | 1999 |
Calcium signaling induced by angiotensin II in the pancreatic acinar cell line AR42J.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Electroporation; Estrenes; Extracellular Space; Imidazoles; Intracellular Fluid; Pancreas; Pyridines; Pyrrolidinones; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Thapsigargin; Type C Phospholipases; Vasoactive Intestinal Peptide | 1999 |
Analysis of responses to angiotensin I (3-10) and Leu3 angiotensin (3-8) in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Male; Peptide Fragments; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
Angiotensin II inhibits interleukin-1 beta-induced nitric oxide production in cultured rat mesangial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cells, Cultured; Gene Expression; Glomerular Mesangium; Imidazoles; Interleukin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta | 1999 |
Role of angiotensin in cardioprotective effect of ischemic preconditioning.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Creatine Kinase; Female; Heart Rate; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyridines; Rats; Rats, Wistar; Tetrazoles | 1999 |
Angiotensin II exacerbates lipopolysaccharide-induced contractile depression in rabbit cardiac myocytes.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cells, Cultured; Chelating Agents; Cyclic GMP; Enzyme Inhibitors; Female; Heart Ventricles; Imidazoles; Indoles; Lipopolysaccharides; Losartan; Male; Mitochondria; Muscle Fibers, Skeletal; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rabbits; Receptors, Angiotensin; Sepsis; Ventricular Function | 1999 |
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclic GMP; Hypertension, Renovascular; Imidazoles; Kidney; Losartan; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation | 1999 |
Effect of luminal angiotensin II receptor antagonists on proximal tubule transport.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium | 1999 |
Vascular angiotensin II receptor and calcium signaling in toadfish.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Blood Vessels; Calcium; Calcium Signaling; Cell Membrane; Female; Fishes; Imidazoles; Losartan; Male; Potassium; Pyridines; Receptors, Angiotensin | 1999 |
Renal cellular response to ureteral obstruction: role of maturation and angiotensin II.
Topics: Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Imidazoles; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Ureteral Obstruction | 1999 |
Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro.
Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Antisense Elements (Genetics); Blotting, Southern; Cells, Cultured; Fibroblasts; Gene Expression; Heart Ventricles; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Losartan; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical | 1999 |
Angiotensin II stimulates DNA and protein synthesis in vascular smooth muscle cells from human arteries: role of extracellular signal-regulated kinases.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arteries; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; DNA; DNA Replication; Humans; Imidazoles; Losartan; Muscle, Smooth, Vascular; Protein Biosynthesis; Pyridines; Receptors, Angiotensin; Signal Transduction; Vasoconstrictor Agents | 1999 |
Modulation of vascular development and injury by angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Carotid Arteries; Catheterization; DNA; Embryonic and Fetal Development; Female; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Aminopeptidase A activity and angiotensin III effects on [Ca2+]i along the rat nephron.
Topics: Aminopeptidases; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Calcium; Glutamyl Aminopeptidase; Imidazoles; Immunohistochemistry; In Vitro Techniques; Intracellular Fluid; Losartan; Male; Nephrons; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 1999 |
Angiotensin II is a growth factor in the peri-implantation rat embryo.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blastocyst; Culture Techniques; Embryonic and Fetal Development; Female; Growth Substances; Imidazoles; Nicotinic Acids; Pyridines; Rats; Rats, Wistar; Statistics, Nonparametric; Tetrazoles | 1999 |
Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation.
Topics: Actins; Amiloride; Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cell Membrane; Cyclic GMP; Endothelium, Vascular; Imidazoles; Kinins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Promoter Regions, Genetic; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; Tunica Media; Vasoconstriction; Vasodilation | 1999 |
In vivo study of AT(1) and AT(2) angiotensin receptors in apoptosis in rat blood vessels.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Apoptosis; Blood Pressure; Body Weight; Drug Interactions; Imidazoles; Losartan; Male; Muscle Development; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 1999 |
Activation of AT(2) receptors by endogenous angiotensin II is involved in flow-induced dilation in rat resistance arteries.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Blotting, Western; Imidazoles; Losartan; Mesenteric Arteries; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Saralasin; Stress, Mechanical; Vascular Resistance; Vasodilation | 1999 |
Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Differentiation; Cell Movement; Cerebellum; Culture Techniques; Fluorescent Antibody Technique, Indirect; Imidazoles; Losartan; Microtubule-Associated Proteins; Neurites; Oligopeptides; Pyridines; Rats; Rats, Long-Evans; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; tau Proteins; Tubulin | 1999 |
Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model.
Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cell Division; Coronary Disease; Coronary Vessels; Culture Techniques; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Recurrence; Swine; Tetrazoles | 1999 |
Angiotensin-(1-7) binds at the type 1 angiotensin II receptors in rat renal cortex.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Iodine Radioisotopes; Kidney Cortex; Losartan; Male; Peptide Fragments; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin | 1999 |
Functional involvement of angiotensin AT2 receptor in adrenal catecholamine secretion in vivo.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcium Channels, L-Type; Catecholamines; Dogs; Imidazoles; Male; Oligopeptides; Pyridines; Receptors, Angiotensin | 1999 |
Angiotensin II receptor blockade during gestation attenuates collagen formation in the developing rat heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Birth Weight; Blotting, Western; Collagen; Female; Heart; Imidazoles; In Situ Hybridization; Losartan; Organ Size; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 1999 |
Participation of angiotensin receptors in acute hypoxia in mice. II. Effects of angiotensin II nonpeptide receptor ligands losartan (DuP-753) and PD-123319.
Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hypoxia, Brain; Imidazoles; Injections, Intraventricular; Ligands; Losartan; Male; Mice; Mice, Inbred ICR; Pyridines; Receptors, Angiotensin; Seizures; Vasoconstrictor Agents | 1999 |
Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice.
Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atropine; Autonomic Nervous System; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hexamethonium; Imidazoles; Mice; Mice, Inbred Strains; Parasympatholytics; Phentolamine; Propranolol; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Losartan reduces the vasorelaxant effect of atrial natriuretic peptide on basal tone in aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Atrial Natriuretic Factor; Calcium; Female; Imidazoles; In Vitro Techniques; Intracellular Fluid; Isotonic Solutions; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance; Vasodilation | 1999 |
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin; Vasoconstriction | 1999 |
The effects of angiotensin metabolites on the regulation of coagulation and fibrinolysis in cultured rat aortic endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Coagulation; Endothelium, Vascular; Fibrinolysis; Gene Expression Regulation; Imidazoles; Lipoproteins; Losartan; Plasminogen Activator Inhibitor 1; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thromboplastin; Tissue Plasminogen Activator | 1999 |
Angiotensin II and retinal pericytes migration.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cattle; Cell Movement; Chemotaxis; Imidazoles; Losartan; Neovascularization, Physiologic; Pericytes; Pyridines; Retina | 1999 |
Angiotensin II-induced superoxide anion generation in human vascular endothelial cells: role of membrane-bound NADH-/NADPH-oxidases.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Lisinopril; Losartan; NADH Dehydrogenase; NADPH Oxidases; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Stimulation, Chemical; Superoxides | 1999 |
Aldosterone secretion by the mid-gestation ovine fetus: role of the AT2 receptor.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Cytochrome P-450 Enzyme System; Female; Fetus; Gestational Age; Imidazoles; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Sheep | 1999 |
Angiotensin III depressor action in the conscious rabbit is blocked by losartan but not PD 123319.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Imidazoles; Losartan; Male; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Angiotensin II and PDGF-BB stimulate beta(1)-integrin-mediated adhesion and spreading in human VSMCs.
Topics: Angiotensin II; Anticoagulants; Antigens, CD; Antihypertensive Agents; Aorta; Becaplermin; Biphenyl Compounds; Carcinogens; Cell Adhesion; Cell Movement; Collagen; Culture Techniques; Enzyme Inhibitors; Fibronectins; Flow Cytometry; Gene Expression; Genistein; Humans; Iliac Artery; Imidazoles; Integrin alpha5; Integrin beta1; Irbesartan; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Vasoconstrictor Agents | 2000 |
Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.
Topics: Actinin; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antigens, CD; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Heart Ventricles; Hydralazine; Imidazoles; Integrin alphaV; Integrin beta Chains; Integrin beta1; Integrin beta3; Integrins; Irbesartan; Laminin; Losartan; Myocardium; Phosphorylation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Up-Regulation; Vitronectin | 2000 |
Functional role of angiotensin II type 1 and 2 receptors in regulation of uterine blood flow in nonpregnant sheep.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; Imidazoles; Injections, Intra-Arterial; Injections, Intravenous; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Sheep; Tetrazoles; Uterus; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Vasoconstriction by in situ formed angiotensin II: role of ACE and chymase.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Child; Child, Preschool; Chymases; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Pyridines; Serine Endopeptidases; Swine; Tetrazoles; Vasoconstriction | 1999 |
Endogenous nitric oxide and epoxyeicosatrienoic acids modulate angiotensin II-induced constriction in the rabbit afferent arteriole.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Male; Miconazole; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Modulation of the AT2 subtype receptor gene activation and expression by the AT1 receptor in endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Endothelium, Vascular; Gene Expression; Gene Expression Regulation; Imidazoles; Losartan; Promoter Regions, Genetic; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcriptional Activation | 1999 |
Brain AT(2) receptor mediate vasodepressor response to footshocks: role of kinins and nitric oxide.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Brain; Electroshock; Enzyme Inhibitors; Extremities; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin | 2000 |
Angiotensin stimulates TGF-beta1 and clusterin in the hydronephrotic neonatal rat kidney.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Clusterin; Glycoproteins; Imidazoles; Kidney; Losartan; Molecular Chaperones; Pyridines; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ureteral Obstruction; Vasoconstrictor Agents | 2000 |
Role of angiotensin II AT1 and AT2 subtype receptors in the regulation of atrial natriuretic peptide expression in salt-restricted rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Imidazoles; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Chloride | 2000 |
Tissue angiotensin II and endothelin-1 modulate differently the response to flow in mesenteric resistance arteries of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Viscosity; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; Losartan; Mesenteric Arteries; Muscle Tonus; Perindopril; Phenylpropionates; Pyridines; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Splanchnic Circulation; Vascular Resistance; Vasodilation | 2000 |
Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase | 2000 |
Angiotensin II induces contraction and proliferation of human hepatic stellate cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Division; Cell Size; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Humans; Imidazoles; Indomethacin; Iodine Radioisotopes; Liver; Losartan; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Penicillamine; Pyridines; Radioligand Assay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Nitrite; Thymidine; Vasoconstrictor Agents | 2000 |
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan | 2000 |
Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Alanine; Amino Acid Sequence; Amino Acid Substitution; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Binding Sites; Binding, Competitive; Cloning, Molecular; COS Cells; DNA, Complementary; DNA, Recombinant; Ferrets; Imidazoles; Iodine Radioisotopes; Losartan; Molecular Sequence Data; Plasmids; Protein Binding; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Threonine | 2000 |
Calcium and osmotic regulation of the Na+/H+ exchanger in neonatal ventricular myocytes.
Topics: Amiloride; Angiotensin II; Animals; Animals, Newborn; Calcium; Calmodulin; Cells, Cultured; CHO Cells; Choline; Cricetinae; Endothelin-1; Heart Ventricles; Imidazoles; Meglumine; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium-Hydrogen Exchangers; Sorbitol; Sulfonamides; Trifluoperazine; Water-Electrolyte Balance | 2000 |
Renin angiotensin system of rabbit clitoral cavernosum: interaction with nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Clitoris; Culture Techniques; Female; Imidazoles; Losartan; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Pyridines; Rabbits; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Angiotensin II releases 20-HETE from rat renal microvessels.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acids; Arterioles; Capillaries; Cytochrome P-450 Enzyme System; Estrenes; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Imidazoles; Kidney; Losartan; Male; NADP; Phosphodiesterase Inhibitors; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Type C Phospholipases | 2000 |
Induction of angiotensin II subtype 2 receptor-mediated blood pressure regulation in synthetic diet-fed rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Captopril; Cardiac Glycosides; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epinephrine; Gene Expression; Imidazoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents; Vasodilation; Weight Gain | 2000 |
Angiotensin II induces leukocyte-endothelial cell interactions in vivo via AT(1) and AT(2) receptor-mediated P-selectin upregulation.
Topics: Angiotensin II; Animals; Cell Communication; Cromolyn Sodium; Endothelium; Flow Cytometry; Imidazoles; Leukocytes; Losartan; P-Selectin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Up-Regulation | 2000 |
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine | 2000 |
Angiotensin II enhances beta-adrenergic receptor-mediated vasorelaxation in aortas from young but not old rats.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Aging; Angiotensin II; Animals; Aorta, Thoracic; Bucladesine; Colforsin; Cyclic AMP; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Phosphodiesterase Inhibitors; Pyridines; Rats; Rats, Inbred F344; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents; Vasodilation | 2000 |
Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis.
Topics: Age Factors; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Autoradiography; Blood Pressure; Cell Division; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; In Situ Nick-End Labeling; Iodine Radioisotopes; Kidney; Male; Oligopeptides; Organ Size; Osteopontin; Proliferating Cell Nuclear Antigen; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan | 2000 |
Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Astrocytes; Autoradiography; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain Chemistry; Diabetes Insipidus; Drinking; Imidazoles; Injections, Intraventricular; Iodine Radioisotopes; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Antisense; Salts; Subfornical Organ; Tetrazoles; Vasoconstrictor Agents | 2001 |
Increased AT(1) receptor expression and mRNA in kidney glomeruli of AT(2) receptor gene-disrupted mice.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Crosses, Genetic; Feedback; Genotype; Imidazoles; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Losartan; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Organ Specificity; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription, Genetic | 2001 |
Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation.
Topics: Angiopoietin-1; Angiopoietin-2; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Cells, Cultured; Cornea; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Gene Expression Regulation; Heparin-binding EGF-like Growth Factor; Imidazoles; In Vitro Techniques; Indoles; Intercellular Signaling Peptides and Proteins; Lymphokines; Maleimides; Membrane Glycoproteins; Naphthalenes; Neovascularization, Physiologic; Olmesartan Medoxomil; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proteins; Pyridines; Quinazolines; Rabbits; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, TIE-2; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, TIE; RNA Stability; RNA, Messenger; Tetrazoles; Time Factors; Transcriptional Activation; Tyrphostins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Characterization of cardioprotection mediated by AT2 receptor antagonism after ischemia-reperfusion in isolated working rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glycolysis; Heart; Imidazoles; Male; Proton Pumps; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reperfusion Injury; Vasoconstrictor Agents; Ventricular Function, Left | 2000 |
Hyperoxia/normoxia-driven retinal angiogenesis in mice: a role for angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Cell Count; Dextrans; Endothelium; Fluoresceins; Humans; Hyperoxia; Hypoxia; Imidazoles; Infant, Newborn; Losartan; Mice; Mice, Inbred C57BL; Perindopril; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retinal Ganglion Cells; Retinal Neovascularization; Retinopathy of Prematurity | 2001 |
Transcriptional and translational regulation of calpain in the rat heart after myocardial infarction--effects of AT(1) and AT(2) receptor antagonists and ACE inhibitor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium-Binding Proteins; Calpain; Disease Models, Animal; Gene Expression Regulation; Heart; Heart Rate; Imidazoles; Male; Myocardial Infarction; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription, Genetic; Valine; Valsartan | 2001 |
Tonic suppression of spontaneous baroreceptor reflex by endogenous angiotensins via AT(2) subtype receptors at nucleus reticularis ventrolateralis in the rat.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Drug Interactions; Functional Laterality; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Neurons; Pressoreceptors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reticular Formation; Time Factors | 2001 |
Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors.
Topics: Adrenal Medulla; Angiotensin II; Animals; Binding Sites; Cattle; Cell Nucleus; Cells, Cultured; Deoxyribonuclease I; DNA Footprinting; Fibroblast Growth Factor 2; Gene Expression Regulation; Imidazoles; Promoter Regions, Genetic; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Response Elements; Signal Transduction; Trans-Activators; Tyrosine | 2001 |
Functional expression of angiotensin II receptors in type-I cells of the rat carotid body.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Carotid Body; Gene Expression; Imidazoles; Immunohistochemistry; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Fluorescence | 2001 |
Angiotensin II-induced depolarizations in hamster submandibular ganglion neurons.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Barium; Cricetinae; Electric Impedance; Ganglia, Parasympathetic; Imidazoles; Losartan; Male; Membrane Potentials; Neurons; Neurotransmitter Agents; Potassium Channels; Pyridines; Receptors, Angiotensin; Sodium Channels; Submandibular Gland | 2000 |
Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Imidazoles; In Vitro Techniques; Losartan; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Patch-Clamp Techniques; Peptides; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetraethylammonium; Vasodilation | 2001 |
p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Collagen; Enzyme Activation; Hypertension; Imidazoles; Irbesartan; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Procollagen; Proline; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thymidine | 2001 |
Atypical angiotensin receptors may mediate water intake induced by central injections of angiotensin II and of serotonin in pigeons.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Columbidae; Drinking Behavior; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Serotonin | 2001 |
Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Imidazoles; Losartan; Male; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptide Fragments; Prostheses and Implants; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2001 |
Brain angiotensin receptors and sympathoadrenal regulation during insulin-induced hypoglycemia.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Brain; Cerebral Ventricles; Epinephrine; Heart Rate; Hemodynamics; Homeostasis; Hypoglycemia; Imidazoles; Injections, Intraventricular; Insulin; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reflex | 2001 |
Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Cell Count; Cell Division; Dose-Response Relationship, Drug; Imidazoles; Liposomes; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Pyridines; Thymidine; Wortmannin | 2001 |
Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amiloride; Angiotensin II; Animals; Antihypertensive Agents; Benzofurans; Biphenyl Compounds; Calcium; Calcium Channel Agonists; Cell Line; Cells, Cultured; Chelating Agents; Cytosol; Dogs; Dose-Response Relationship, Drug; Egtazic Acid; Ethers, Cyclic; Fluorescent Dyes; Fura-2; Imidazoles; Imipramine; Irbesartan; Kidney; Kinetics; Magnesium; Microscopy, Fluorescence; Peptides; Pyridines; Quinidine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Tetrazoles; Time Factors | 2001 |
Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure Determination; Consciousness; Iloprost; Imidazoles; In Vitro Techniques; Losartan; Male; Microcirculation; Muscle, Skeletal; Muscle, Smooth, Vascular; Oxygen; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sodium, Dietary; Vascular Resistance; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2001 |
Angiotensin receptor in the heart of Bothrops jararaca snake.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Amide; Angiotensin II; Animals; Binding, Competitive; Bothrops; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Female; Imidazoles; Inositol Phosphates; Losartan; Male; Membranes; Myocardium; Pyridines; Receptors, Angiotensin; Saralasin; Tritium | 2001 |
Effects of angiotensin-converting enzyme and angiotensin II on hypoxia-induced proliferation of cultured intra-pulmonary artery smooth muscle cells.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Division; Cell Hypoxia; Cells, Cultured; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Rabbits | 2000 |
Systemic infusion of angiotensin II into normal rats activates nuclear factor-kappaB and AP-1 in the kidney: role of AT(1) and AT(2) receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Line; Dose-Response Relationship, Drug; Female; Imidazoles; Infusion Pumps; Kidney; Losartan; NF-kappa B; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Transcription Factor AP-1 | 2001 |
Regulation of K+ transport in the rat distal colon via angiotensin II subtype receptors and K+ -pathways.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport, Active; Carrier Proteins; Colon; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Losartan; Male; Potassium; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase | 2001 |
Central AT1 and AT2 receptors mediate chronic intracerebroventricular angiotensin II-induced drinking in rats fed high sodium chloride diet from weaning.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brain; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Imidazoles; Injections, Intraventricular; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium, Dietary | 2001 |
Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Imidazoles; Kidney Tubules, Proximal; Losartan; Nephrons; Nitrendipine; Parathyroid Hormone; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Second Messenger Systems; Sodium; Thionucleotides; Vasoconstrictor Agents | 2001 |
Chronotropic effect of angiotensin II via type 2 receptors in rat brain neurons.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Action Potentials; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arachidonic Acids; Brain; Cytarabine; Enzyme Inhibitors; Imidazoles; Lipoxygenase; Lipoxygenase Inhibitors; Losartan; Nerve Tissue Proteins; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Synaptic Transmission; Tetrodotoxin; Time Factors | 2001 |
Endogenous angiotensin II in the NTS contributes to sympathetic activation in rats with aortocaval shunt.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Arteriovenous Shunt, Surgical; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Echocardiography; Heart Rate; Hemodynamics; Imidazoles; Kidney; Male; Microinjections; Pyridines; Rats; Rats, Inbred WKY; Solitary Nucleus; Sympathetic Nervous System; Tetrazoles; Venae Cavae | 2001 |
Angiotensin II activates nuclear transcription factor-kappaB in aorta of normal rats and in vascular smooth muscle cells of AT1 knockout mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Binding Sites; Cells, Cultured; Consensus Sequence; Endothelium, Vascular; Gene Expression Regulation; Imidazoles; Losartan; Mice; Mice, Knockout; Models, Biological; Muscle, Smooth, Vascular; NF-kappa B; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transcription Factors | 2001 |
Intracellular angiotensin II elicits Ca2+ increases in A7r5 vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Calcium; Cell Line; Cell Membrane Permeability; Dose-Response Relationship, Drug; Imidazoles; Inositol 1,4,5-Trisphosphate; Liposomes; Losartan; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Potassium Chloride; Pyridines | 2001 |
Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Extracellular Space; Imidazoles; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrazoles; Virulence Factors, Bordetella | 2001 |
Angiotensin II AT(2) receptors inhibit growth responses in proximal tubule cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Calcium; Cell Division; Cell Line; DNA; Epidermal Growth Factor; Imidazoles; Immunoblotting; Kidney Tubules, Proximal; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Pyridines; Radioligand Assay; Receptors, Angiotensin; Transfection; Vanadates | 2001 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase | 2001 |
Angiotensin II type 2 receptor inhibits epidermal growth factor receptor transactivation by increasing association of SHP-1 tyrosine phosphatase.
Topics: Angiotensin II; Animals; Cells, Cultured; ErbB Receptors; Fibronectins; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-fos; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription Factor AP-1 | 2001 |
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation | 2001 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission | 2001 |
Angiotensin II induces circadian gene expression of clock genes in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Benzimidazoles; Biological Clocks; Biomarkers; Biphenyl Compounds; Blotting, Northern; Cell Cycle Proteins; Cells, Cultured; Circadian Rhythm; DNA-Binding Proteins; Gene Expression; Imidazoles; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Nuclear Proteins; Period Circadian Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription Factors | 2001 |
Increased AT(1) receptors in adrenal gland of AT(2) receptor gene-disrupted mice.
Topics: Adrenal Medulla; Angiotensin II; Animals; Autoradiography; Blood Pressure; Female; Gene Expression Regulation; Genotype; Imidazoles; In Situ Hybridization; Losartan; Mice; Mice, Inbred Strains; Mice, Knockout; Mice, Mutant Strains; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Transcription, Genetic; Vasoconstrictor Agents; Zona Glomerulosa | 2001 |
Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Drug Synergism; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Severity of Illness Index | 2001 |
Angiotensin subtype-2 receptor (AT2 ) negatively regulates subtype-1 receptor (AT1 ) in signal transduction pathways in cultured porcine adrenal medullary chromaffin cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA-Binding Proteins; Drug Combinations; Enzyme Activation; Imidazoles; Isoenzymes; Milk Proteins; Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; STAT5 Transcription Factor; Swine; Tetrazoles; Trans-Activators | 2001 |
Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue.
Topics: Absorptiometry, Photon; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Female; Granulosa Cells; Image Processing, Computer-Assisted; Imidazoles; Immunohistochemistry; Nicotinic Acids; Ovary; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sexual Maturation; Swine; Tetrazoles | 2001 |
Angiotensin II in cardiac pressure-overload hypertrophy in fetal sheep.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Brain; Cardiomegaly; Female; Gestational Age; Heart; Imidazoles; Kidney; Lung; Organ Size; Phenylephrine; Pregnancy; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 2; Sheep | 2001 |
AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Cardiac Output; Coronary Circulation; Heart Failure; Heart Rate; Imidazoles; Irbesartan; Male; Myocardial Infarction; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Survival Rate; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2001 |
Blockade of angiotensin receptor subtypes in arcuate uterine artery of pregnant and postpartum rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Interactions; Female; Imidazoles; Losartan; Postpartum Period; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Regulation of vascular proteoglycan synthesis by angiotensin II type 1 and type 2 receptors.
Topics: Aggrecans; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; DNA, Complementary; Extracellular Matrix Proteins; Glycoproteins; Heparan Sulfate Proteoglycans; Imidazoles; Lectins, C-Type; Losartan; Male; Muscle, Smooth, Vascular; Proteoglycans; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger | 2001 |
Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cell Membrane; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Tubules, Proximal; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saralasin; Sodium-Potassium-Exchanging ATPase; Swine | 2002 |
Chronic hypotensive effects of losartan are not dependent on the actions of angiotensin II at AT 2 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Chloride, Dietary; Water-Electrolyte Balance | 2002 |
Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradykinin; Dogs; Heart; Hemodynamics; Imidazoles; Microdialysis; Myocardium; Peptide Fragments; Peptides; Pyridines | 2002 |
Differential effect of angiotensin II on blood circulation in the renal medulla and cortex of anaesthetised rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Imidazoles; Kidney Cortex; Kidney Medulla; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Saralasin; Vasoconstrictor Agents | 2002 |
Vasoconstriction is determined by interstitial rather than circulating angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Carotid Arteries; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Irbesartan; Isoquinolines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Intracellular angiotensin II inhibits heterologous receptor stimulated Ca2+ entry.
Topics: Angiotensin II; Animals; Calcium; Cell Line; Imidazoles; Liposomes; Losartan; Muscle, Smooth; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Serotonin; Uridine Triphosphate | 2001 |
Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.
Topics: Angiotensin II; Animals; Antibodies; Anticoagulants; Antihypertensive Agents; Becaplermin; Cattle; Cells, Cultured; Chemotaxis; Dipeptides; Endothelial Growth Factors; Imidazoles; Losartan; Lymphokines; Matrix Metalloproteinase 2; Microcirculation; Neovascularization, Physiologic; Pericytes; Platelet-Derived Growth Factor; Protease Inhibitors; Proto-Oncogene Proteins c-sis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retina; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents | 2002 |
The mechanism of angiotensin II binding downregulation by high glucose in primary renal proximal tubule cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Calcium Channel Blockers; Carcinogens; Cells, Cultured; Dose-Response Relationship, Drug; Gene Expression; Glucose; Imidazoles; Iodine Radioisotopes; Kidney Tubules, Proximal; Lipid Peroxidation; Losartan; Nifedipine; Oxidants; Oxidative Stress; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Rabbits; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Vasoconstrictor Agents | 2002 |
Angiotensin II directly stimulates macula densa Na-2Cl-K cotransport via apical AT(1) receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biological Transport; Biphenyl Compounds; Cytosol; Diuretics; Furosemide; Imidazoles; Kidney Glomerulus; Microscopy, Fluorescence; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Tetrazoles; Vasoconstrictor Agents | 2002 |
Dilatation of cerebral parenchymal vessels mediated by angiotensin type 1 receptor in cats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Microcirculation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasodilation | 2002 |
Angiotensin II type 2 receptor counter-regulates type 1 receptor in catecholamine synthesis in cultured porcine adrenal medullary chromaffin cells.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Catecholamines; Cells, Cultured; Cyclic GMP; Imidazoles; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase | 2002 |
AT(2) but not AT(1) receptor antagonism abolishes angiotensin II increase of the acquisition of conditioned avoidance responses in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Avoidance Learning; Cognition; Conditioning, Operant; Exploratory Behavior; Imidazoles; Injections, Intraventricular; Losartan; Male; Mental Recall; Motor Activity; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2002 |
Angiotensin receptor subtype AT(1) mediates alveolar epithelial cell apoptosis in response to ANG II.
Topics: Adenocarcinoma; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Apoptosis; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Imidazoles; Losartan; Lung Neoplasms; Pulmonary Alveoli; Pulmonary Fibrosis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Respiratory Mucosa; Tetrazoles; Tumor Cells, Cultured; Vasoconstrictor Agents | 2002 |
Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Cells, Cultured; Collagen; Fibroblasts; Fluorescent Antibody Technique; Imidazoles; Male; Myocardium; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Telmisartan; Vasoconstrictor Agents | 2001 |
Influence of estrogen and/or progesterone on isolated ovariectomized rat uterus. Responsiveness to Ang II.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Estrogens; Female; Imidazoles; In Vitro Techniques; Losartan; Muscle Contraction; Ovariectomy; Progesterone; Pyridines; Rats; Rats, Wistar; Uterus | 2002 |
Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Male; Norepinephrine; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
The effect of angiotensin II on mitogen-activated protein kinase in human cardiomyocytes.
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Culture Techniques; Drug Synergism; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Losartan; Middle Aged; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2000 |
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins | 2002 |
No net effect of angiotensin II on blood pressure?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypotension; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2 | 2002 |
Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Female; Imidazoles; Injections, Intravenous; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2002 |
Angiotensin actions on the isolated rat uterus during the estrous cycle: influence of resting membrane potential and uterine morphology.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Estrous Cycle; Female; Imidazoles; In Vitro Techniques; Losartan; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Uterus; Vasoconstrictor Agents | 2002 |
Angiotensin II induces apoptosis in rat glomerular epithelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Antihypertensive Agents; bcl-2-Associated X Protein; Cells, Cultured; DNA Fragmentation; Epithelial Cells; Fas Ligand Protein; fas Receptor; Imidazoles; Kidney Glomerulus; Losartan; Membrane Glycoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2002 |
Angiotensin II angiogenic effect in vivo involves vascular endothelial growth factor- and inflammation-related pathways.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Collagen; Cyclooxygenase 2; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Endothelial Growth Factors; Female; Imidazoles; Isoenzymes; Laminin; Lymphokines; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Prostaglandin-Endoperoxide Synthases; Proteoglycans; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfonamides; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Aldosterone breakthrough during angiotensin II receptor antagonist therapy in stroke-prone spontaneously hypertensive rats.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Corticosterone; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertension; Imidazoles; Male; Natriuretic Peptide, Brain; Prodrugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Spironolactone; Stroke; Tetrazoles; Time Factors | 2002 |
Role of angiotensin II and angiotensin II receptors in vascular smooth muscle cell migration in vitro.
Topics: Actins; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cell Movement; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Female; Focal Adhesions; Imidazoles; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles | 2002 |
Interaction between paraventricular nucleus and septal area in the control of physiological responses induced by angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Drinking; Imidazoles; Losartan; Male; Natriuresis; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Sodium, Dietary; Vasoconstrictor Agents | 2002 |
Cross-talk between AT(1) and AT(2) angiotensin receptors in rat anococcygeus smooth muscle.
Topics: Angiotensin II; Animals; Imidazoles; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2002 |
Biphasic regulation of Na+-HCO3- cotransporter by angiotensin II type 1A receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Bicarbonates; Calcium; Dose-Response Relationship, Drug; Enzyme Activators; Fluorescent Dyes; Imidazoles; In Vitro Techniques; Intracellular Fluid; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Sodium-Bicarbonate Symporters; Tetrazoles; Valine; Valsartan | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
ANG II AT2 receptor modulates AT1 receptor-mediated descending vasa recta endothelial Ca2+ signaling.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Signaling; Cytoplasm; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Kidney Medulla; Losartan; Manganese; Microcirculation; Muscle, Smooth, Vascular; Pericytes; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction; Vasodilator Agents | 2003 |
Intrarenal infusion of angiotensin-(1-7) modulates renal functional responses to exogenous angiotensin II in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Glomerular Filtration Rate; Imidazoles; In Vitro Techniques; Kidney; Kidney Function Tests; Male; Organ Size; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Circulation; Sodium; Urodynamics | 2002 |
Dose-dependent regulation of NAD(P)H oxidase expression by angiotensin II in human endothelial cells: protective effect of angiotensin II type 1 receptor blockade in patients with coronary artery disease.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Coronary Artery Bypass; Coronary Artery Disease; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Mammary Arteries; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Preoperative Care; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Retrospective Studies; Superoxides; Tetrazoles; Umbilical Veins | 2002 |
Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cardiomyopathies; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Matrix; Fibroblasts; Fibrosis; Imidazoles; Losartan; Matrix Metalloproteinase 2; Proline; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tissue Inhibitor of Metalloproteinase-1; Tumor Necrosis Factor-alpha; Up-Regulation | 2002 |
Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Homeostasis; Imidazoles; Immune Sera; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Time Factors | 2003 |
Prostaglandins contribute to impaired angiotensin II-induced cerebral vasodilation after brain injury.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Brain Injuries; Cerebral Cortex; Female; Imidazoles; Male; Naphthyridines; Prostaglandins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Vasodilation | 2002 |
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arginine Vasopressin; Benzoquinones; Calcium; Cysteine; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Losartan; Myocardium; Propionates; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spectrometry, Fluorescence | 2003 |
Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Imidazoles; Irbesartan; Male; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Saralasin; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles | 2002 |
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function.
Topics: Adenosine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; In Vitro Techniques; Losartan; Microcirculation; NADPH Oxidases; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxides; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System | 2003 |
Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Epithelial Cells; Flow Cytometry; Humans; Imidazoles; In Situ Nick-End Labeling; In Vitro Techniques; Kidney Failure, Chronic; Kidney Tubules; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2002 |
Angiotensin II-induced release of oxytocin: interaction with norepinephrine and role in lactation.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Suckling; Female; Imidazoles; Injections, Intraventricular; Lactation; Losartan; Norepinephrine; Oxytocin; Phentolamine; Pyridines; Rats; Third Ventricle | 2003 |
The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception.
Topics: Angiotensin II; Animals; Avoidance Learning; Disease Models, Animal; Drug Combinations; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Memory; Mice; Pain Measurement; Pentylenetetrazole; Pyridines; Seizures; Tail | 2003 |
Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Gene Expression Regulation, Enzymologic; Imidazoles; Isoprostanes; Kidney; Male; Malondialdehyde; NADPH Oxidases; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxide Dismutase; Tetrazoles; Vasoconstrictor Agents | 2003 |
Role of the angiotensin II system in regulation of ovulation and blood flow in the rat ovary.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dinoprostone; Drug Synergism; Female; Imidazoles; Laser-Doppler Flowmetry; Losartan; Ovary; Ovulation; Plasminogen Activators; Pyridines; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2003 |
Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Functional Laterality; Ganglionectomy; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Nodose Ganglion; Oligopeptides; Pyridines; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Solitary Nucleus | 2003 |
Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Losartan; Male; Minoxidil; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2003 |
Cardiac myofibroblasts: a novel source of vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Fibroblasts; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardium; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2003 |
Angiotensin II AT(1) and AT(2) receptors contribute to maintain basal adrenomedullary norepinephrine synthesis and tyrosine hydroxylase transcription.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Chromaffin Cells; Epinephrine; Ganglia; Imidazoles; Immunohistochemistry; Male; Neurons; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tissue Distribution; Transcription Factors; Transcription, Genetic; Tyrosine 3-Monooxygenase | 2003 |
Influence of angiotensin II receptor subtypes of the paraventricular nucleus on the physiological responses induced by angiotensin II injection into the medial septal area.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Drinking; Homeostasis; Imidazoles; Losartan; Male; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Saralasin; Septum of Brain; Sodium; Vasoconstrictor Agents | 2003 |
No involvement of the AT2-receptor in angiotensin II-enhanced sympathetic transmission in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Synergism; Electric Stimulation; Imidazoles; In Vitro Techniques; Irbesartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Tritium; Vasoconstrictor Agents; Vena Cava, Inferior | 2003 |
Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2003 |
Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.
Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Immunohistochemistry; In Vitro Techniques; Losartan; Male; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Spinal Cord; Synaptophysin | 2003 |
Angiotensin II and III microinjections into the zona incerta influence drinking behavior.
Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Interactions; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Pyridines; Rats; Subthalamus; Time Factors | 2003 |
Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Blotting, Western; Cell Line; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Losartan; Lymphokines; Neovascularization, Physiologic; Oligopeptides; Pertussis Toxin; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2003 |
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance | 2003 |
Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Cells, Cultured; Connective Tissue Growth Factor; Drug Administration Routes; Drug Administration Schedule; Extracellular Matrix Proteins; Female; Fibrosis; Gene Expression; Imidazoles; Immediate-Early Proteins; Immunohistochemistry; Infusion Pumps, Implantable; Intercellular Signaling Peptides and Proteins; Losartan; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger | 2003 |
Effect of simultaneous blockade of AT1 and AT2 receptors on the NFkappaB pathway and renal inflammatory response.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Imidazoles; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis; NF-kappa B; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2003 |
Dietary salt intake modulates progression of antithymocyte serum nephritis through alteration of glomerular angiotensin II receptor expression.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Body Weight; Female; Glomerulonephritis; Imidazoles; Kidney Glomerulus; Macrophages; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; Renin; Sheep; Sodium Chloride, Dietary; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Hypertrophic; Fibroblast Growth Factor 1; Gene Expression Regulation; Genes, fos; Heart Rate; Hypertension; Imidazoles; Infusion Pumps, Implantable; Losartan; Male; Natriuretic Peptide, Brain; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Vascular Endothelial Growth Factor A | 2003 |
Effects of angiotensin II on nitric oxide generation in growing and resting rat aortic endothelial cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcimycin; Cell Division; Cells, Cultured; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Ionophores; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation | 2003 |
Effects of angiotensin II on nitric oxide generation in proliferating and quiescent rat coronary microvascular endothelial cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Northern; Blotting, Western; Calcimycin; Coronary Vessels; Endothelial Cells; Imidazoles; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Valine; Valsartan | 2003 |
Different AT1 receptor subtypes at pre- and postjunctional sites: AT1A versus AT1B receptors.
Topics: Angiotensin II; Animals; Drug Interactions; Electric Stimulation; Imidazoles; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Vasoconstrictor Agents | 2004 |
Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Imidazoles; Immunoblotting; Kidney; Oligopeptides; Phosphorylation; Phosphotyrosine; Pyridines; Rats; Rats, Inbred WKY; Signal Transduction; Tyrosine; Vanadates | 2003 |
Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Chemokine CCL2; Cytosol; Gene Expression Regulation; I-kappa B Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Mutation; NF-kappa B; Oligopeptides; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2004 |
Retinal expression of vascular endothelial growth factor is mediated by angiotensin type 1 and type 2 receptors.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Diabetes Mellitus, Experimental; Gene Expression; Imidazoles; Immunohistochemistry; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retina; Vascular Endothelial Growth Factor A | 2004 |
Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Blotting, Western; Dose-Response Relationship, Drug; Gene Expression; Glucose; Imidazoles; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Losartan; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Peptidyl-Dipeptidase A; Proinsulin; Protein Biosynthesis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Bradykinin; Hypertension; Hypothalamus; Imidazoles; In Vitro Techniques; Nitric Oxide; Norepinephrine; Peptide Fragments; Potassium; Pyridines; Rats; Rats, Wistar | 2004 |
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomyopathy, Hypertrophic; Coronary Vessels; Disease Models, Animal; Enzyme Induction; Imidazoles; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2004 |
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.
Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine | 2004 |
Involvement of the renin-angiotensin system in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Brain Chemistry; Captopril; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hindlimb; Histamine; Histamine N-Methyltransferase; Hypotension; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intravenous; Injections, Intraventricular; Male; Medulla Oblongata; Naphthyridines; Pyridines; Pyrimethamine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Resuscitation; Shock, Hemorrhagic; Time Factors; Vascular Resistance | 2004 |
Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Allosteric Regulation; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Brain; Calcium Signaling; CHO Cells; Cricetinae; Cricetulus; Gene Expression; Genes, Synthetic; Glial Fibrillary Acidic Protein; Globins; Humans; Hypertension; Imidazoles; Mice; Mice, Transgenic; Organ Specificity; Protein Sorting Signals; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Renin; Renin-Angiotensin System; Tetrazoles; Transgenes | 2004 |
Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Biphenyl Compounds; Child; Child, Preschool; Coronary Circulation; Coronary Vessels; Cyclic GMP; Female; Humans; Imidazoles; Irbesartan; Male; Microcirculation; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; RNA, Messenger; Tetrazoles; Vasodilation | 2004 |
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction | 2004 |
Angiotensin II stimulates the release of interleukin-6 and interleukin-8 from cultured human adipocytes by activation of NF-kappaB.
Topics: Adipocytes; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Electrophoretic Mobility Shift Assay; Female; Humans; Imidazoles; Inflammation; Interleukin-6; Interleukin-8; NF-kappa B; Nitriles; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Receptor, Angiotensin, Type 1; RNA, Messenger; Sulfones; Tetrazoles; Transcription Factor RelA; Transcriptional Activation | 2004 |
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation | 2004 |
Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.
Topics: Adjuvants, Immunologic; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Imidazoles; Kidney Cortex; Losartan; Peptide Fragments; Pertussis Toxin; Pyridines; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents | 2004 |
Angiotensin II-induced relaxation of anococcygeus smooth muscle via desensitization of AT1 receptor, and activation of AT2 receptor associated with nitric-oxide synthase pathway.
Topics: Adenine; Angiotensin II; Animals; Blotting, Western; CD13 Antigens; Drug Interactions; Glutamyl Aminopeptidase; Imidazoles; Losartan; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Peptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrodotoxin; Thiorphan | 2004 |
Altered effects of angiotensin ii type 1 and type 2 receptor blockers on cardiac norepinephrine release and inotropic responses during cardiac sympathetic nerve stimulation in aorto-caval shunt rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Arteriovenous Shunt, Surgical; Echocardiography; Heart; Heart Conduction System; Imidazoles; Male; Myocardial Contraction; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reference Values; Vena Cava, Inferior; Ventricular Function, Left | 2004 |
Effects of angiotensin II type 1 receptor antagonist on pressor responses to pulsatile compression of the rostral ventrolateral medulla in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Hypertension; Imidazoles; Injections, Intravenous; Kynurenic Acid; Male; Medulla Oblongata; Pulsatile Flow; Pyridines; Rats; Rats, Wistar; Sympathetic Nervous System; Tetrazoles; Vasoconstrictor Agents | 2004 |
Metabolism of angiotensin II is required for its in vivo effect on dopamine release in the striatum of the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Hemoglobins; Imidazoles; Male; Methionine; Microdialysis; Naltrexone; Narcotic Antagonists; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonic Acids; Tetrazoles; Time Factors | 2004 |
Angiotensin II attenuates NMDA receptor-mediated neuronal cell death and prevents the associated reduction in Bcl-2 expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Death; Cell Line; Cell Survival; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Imidazoles; Losartan; N-Methylaspartate; Neurons; Proto-Oncogene Proteins c-bcl-2; Pyridines; Receptors, Angiotensin; Receptors, N-Methyl-D-Aspartate; Vasoconstrictor Agents | 2004 |
Effect of angiotensin II type 1 receptor on delayed rectifier potassium current in catecholaminergic CATH.a cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Catecholamines; Cell Line; Delayed Rectifier Potassium Channels; Imidazoles; Locus Coeruleus; Losartan; Mice; Naphthalenes; Potassium Channels, Voltage-Gated; Protein Kinase C; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sulfonamides; Type C Phospholipases | 2004 |
Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cells, Cultured; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Interactions; Embryo, Mammalian; Glial Fibrillary Acidic Protein; Imidazoles; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Naphthyridines; Nerve Tissue Proteins; Neurons; Phosphopyruvate Hydratase; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stem Cells; Tubulin; Tyrosine 3-Monooxygenase | 2004 |
Angiotensin II-dependent induction of AT(2) receptor expression after renal ablation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Diuresis; Gene Expression Regulation; Imidazoles; Kidney; Ligation; Losartan; Male; Nephrectomy; Proteinuria; Pyridines; Ramipril; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Artery; RNA, Messenger | 2005 |
A pharmacological differentiation between postjunctional (AT1A) and prejunctional (AT1B) angiotensin II receptors in the rabbit aorta.
Topics: Angiotensin II; Angiotensin III; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Female; Imidazoles; In Vitro Techniques; Male; Pyridines; Rabbits; Receptor, Angiotensin, Type 1 | 2004 |
Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WF; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 2005 |
Mechanisms of impaired vascular response to ANG II in perivascular injured carotid arteries of ovariectomized rat.
Topics: Angiotensin II; Animals; Calcium; Carotid Artery Injuries; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Implants, Experimental; Indomethacin; Muscle, Smooth, Vascular; Neovascularization, Pathologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ovariectomy; Photomicrography; Pyridines; Rabbits; Rats; Rats, Wistar; Silicones; Time Factors; Vasoconstriction | 2004 |
Angiotensin AT2 receptor contributes to cardiovascular remodelling of aged rats during chronic AT1 receptor blockade.
Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiomegaly; Fibrosis; Heart Rate; Hypertrophy; Imidazoles; Myocardium; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Telemetry; Tetrazoles; Ventricular Remodeling | 2004 |
Angiotensin II type 1 receptor activation increases microvascular hydraulic permeability.
Topics: Analysis of Variance; Angiotensin II; Animals; Cell Membrane Permeability; Female; Imidazoles; Kinetics; Microcirculation; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Splanchnic Circulation; Venules | 2004 |
ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cell Line; Chemokine CCL2; Chemokines; Down-Regulation; Drug Interactions; Endothelium, Vascular; Humans; Imidazoles; Interleukin-8; Losartan; Monocytes; NF-kappa B; Peptidyl-Dipeptidase A; Pyridines; Ramipril; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Simvastatin; Umbilical Veins | 2004 |
Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Consciousness; Depression, Chemical; Female; Imidazoles; Injections; Juxtaglomerular Apparatus; Kidney Cortex; Kidney Tubules; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium, Dietary; Systole; Tetrazoles; Valine; Valsartan | 2005 |
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan | 2004 |
Central angiotensin II AT1 receptors mediate fetal swallowing and pressor responses in the near-term ovine fetus.
Topics: Angiotensin II; Animals; Anti-Arrhythmia Agents; Blood Gas Analysis; Blood Pressure; Brain Chemistry; Deglutition; Drinking; Electromyography; Female; Fetus; Imidazoles; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sheep | 2005 |
Angiotensin II blocks memory consolidation through an AT2 receptor-dependent mechanism.
Topics: Amnesia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraventricular; Male; Memory; Motor Activity; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2 | 2005 |
Angiotensin II stimulates Pax-2 in rat kidney proximal tubular cells: impact on proliferation and apoptosis.
Topics: Angiotensin II; Animals; Apoptosis; Cell Division; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression; Genistein; Imidazoles; Janus Kinase 2; Kidney Tubules, Proximal; PAX2 Transcription Factor; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Rats; Signal Transduction; Transcription Factors; Transformation, Genetic; Tyrphostins; Up-Regulation; Vasoconstrictor Agents | 2004 |
Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Azaserine; Cell Line; Gene Expression Regulation; Glucose; Imidazoles; Indicators and Reagents; Indoles; Insulin; Kidney Tubules, Proximal; Losartan; Maleimides; Perindopril; Protein Kinase C; Pyridines; Rats; Reactive Oxygen Species; Renin | 2004 |
Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Diuresis; Imidazoles; Kidney; Male; Natriuresis; Obesity; Oligopeptides; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation | 2005 |
Protein kinase C-mediated inhibition of renal Ca2+ ATPase by physiological concentrations of angiotensin II is reversed by AT1- and AT2-receptor antagonists.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Calcium-Transporting ATPases; Cells, Cultured; Dose-Response Relationship, Drug; Imidazoles; Kidney Tubules, Proximal; Losartan; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sheep; Vasoconstrictor Agents | 2005 |
NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Calcium Signaling; Catalase; Cells, Cultured; Cyclic N-Oxides; Delayed Rectifier Potassium Channels; Drinking Behavior; Glycoproteins; Heart Rate; Hypothalamus; Imidazoles; Injections, Intraventricular; Ion Channel Gating; Losartan; Male; NADPH Oxidases; Neurons; Polyethylene Glycols; Potassium Channels, Voltage-Gated; Pyridines; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Spin Labels; Telemetry; Xanthine; Xanthine Oxidase | 2005 |
Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.
Topics: Adipocytes; Angiotensin II; Animals; Cell Size; Dietary Fats; Energy Metabolism; Hypertension; Imidazoles; Insulin Resistance; Mice; Mice, Knockout; Muscle, Skeletal; Obesity; Pyridines; Receptor, Angiotensin, Type 2 | 2005 |
Angiotensin II stimulates arachidonic acid release from bone marrow stromal cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arachidonic Acid; Bone Marrow Cells; Cells, Cultured; Humans; Imidazoles; Losartan; Macaca fascicularis; Macrophage Colony-Stimulating Factor; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stromal Cells | 2004 |
Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Cells, Cultured; Coronary Artery Disease; Dinoprostone; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypertension; Imidazoles; Matrix Metalloproteinase 1; Monocytes; Myocardial Infarction; Oligopeptides; Phosphoprotein Phosphatases; Pyridines; Receptor, Angiotensin, Type 2; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
Candesartan prevents angiotensin II-induced facilitation of hypoxic neuronal damage through PKCdelta inhibition.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Death; Cell Hypoxia; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Imidazoles; In Situ Nick-End Labeling; Mice; PC12 Cells; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyridines; Rats; Serine; Tetrazoles; Time Factors; Transfection | 2005 |
Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Calcium; Calcium Signaling; Cell Nucleus; Chickens; Cytosol; Dose-Response Relationship, Drug; Heart Ventricles; Imidazoles; Indoles; Maleimides; Microscopy, Confocal; Myocytes, Cardiac; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Ventricular Function | 2005 |
The effect of angiotensin III on protein tyrosine kinase activity in rat pituitary.
Topics: Angiotensin II; Angiotensin III; Animals; CD13 Antigens; Imidazoles; Losartan; Methionine; Peptides; Pituitary Gland; Protein Binding; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2005 |
Tubular expression of angiotensin II receptors and their regulation in IgA nephropathy.
Topics: Angiotensin II; Apoptosis; Cells, Cultured; Culture Media, Conditioned; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Epithelial Cells; Gene Expression Regulation; Glomerulonephritis, IGA; Humans; Imidazoles; Immunoblotting; Immunoglobulin A; Immunohistochemistry; Inflammation; Interleukin-6; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Kinetics; Losartan; MAP Kinase Signaling System; Mesangial Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; Poly(ADP-ribose) Polymerases; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Recombinant Proteins; Renin-Angiotensin System; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists.
Topics: Amino Acid Substitution; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Benzodiazepines; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Female; Imidazoles; In Vitro Techniques; Ligands; Liver; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Molecular; Molecular Mimicry; Myometrium; Neurites; Protein Conformation; Pyridines; Radioligand Assay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Swine | 2005 |
ANG II increases 2-deoxyglucose uptake in mouse embryonic stem cells.
Topics: Alkaline Phosphatase; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Transport; Calcimycin; Calcium; Cell Line; Cell Proliferation; Deoxyglucose; DNA-Binding Proteins; Dose-Response Relationship, Drug; Embryo, Mammalian; Estrenes; Gene Expression; Glucose Transporter Type 1; Imidazoles; Inositol Phosphates; Losartan; Membrane Transport Proteins; Mice; Monosaccharide Transport Proteins; Neomycin; Octamer Transcription Factor-3; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Pyrrolidinones; Stem Cells; Transcription Factors; Type C Phospholipases; Vasoconstrictor Agents | 2005 |
Diminution of angiotensin II-induced contraction of the abdominal aorta isolated from Watanabe heritable hyperlipidemic rabbits.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Arteriosclerosis; Body Weight; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hyperlipidemias; Imidazoles; In Vitro Techniques; Lipids; Male; Nitroarginine; Pyridines; Rabbits; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Electrophysiological properties of rostral ventrolateral medulla neurons in angiotensin II 1a receptor knockout mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Electrophysiology; Imidazoles; Medulla Oblongata; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles | 2005 |
Does the AT2-receptor mediate anti-atherosclerotic actions?
Topics: Angiotensin II; Animals; Apolipoproteins; Arteriosclerosis; Blood Pressure; Cholesterol, Dietary; Imidazoles; Male; Mice; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; Vasoconstrictor Agents | 2005 |
Angiotensin II infusion increases hepatic triglyceride production via its type 2 receptor in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Fatty Acids, Nonesterified; Imidazoles; Liver; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Triglycerides; Vasoconstrictor Agents | 2005 |
Angiotensin II, type 2 receptor is not involved in the angiotensin II-mediated pro-atherogenic process in ApoE-/- mice.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Cholesterol, Dietary; Imidazoles; Immunohistochemistry; Mice; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; Vasoconstrictor Agents | 2005 |
Angiotensin II and interleukin-1 interact to increase generation of dopaminergic neurons from neurospheres of mesencephalic precursors.
Topics: Analysis of Variance; Angiotensin II; Animals; Cell Count; Cells, Cultured; Dopamine; Drug Interactions; Embryo, Mammalian; Glial Fibrillary Acidic Protein; Imidazoles; Interleukin-1; Mesencephalon; Naphthyridines; Neurons; Pyridines; Rats; Stem Cells; Tubulin; Tyrosine 3-Monooxygenase | 2005 |
Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Imidazoles; Kidney; Microinjections; Muscimol; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System | 2005 |
Dose-dependent systemic and renal haemodynamic effects of angiotensin II in conscious lambs: role of angiotensin AT1 and AT2 receptors.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Naphthyridines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Sheep | 2005 |
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Sulfonic Acids; Tetrazoles; Time Factors | 2005 |
Coexpression of AT1 and AT2 receptors by human fibroblasts is associated with resistance to angiotensin II.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Blotting, Northern; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen Type I; Culture Media, Serum-Free; Fibroblasts; Gene Expression; Humans; Imidazoles; Losartan; Myocytes, Smooth Muscle; Procollagen; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Vasoconstrictor Agents | 2005 |
Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null mice.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Gene Deletion; Imidazoles; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 2005 |
NADPH oxidase-derived superoxide anion mediates angiotensin II-induced pressor effect via activation of p38 mitogen-activated protein kinase in the rostral ventrolateral medulla.
Topics: Angiotensin II; Animals; Blood Pressure; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Losartan; Male; Medulla Oblongata; NADPH Oxidases; Oligonucleotides, Antisense; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Superoxides; Sympathetic Nervous System | 2005 |
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Drug Synergism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents | 2005 |
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Astrocytes; Carboxypeptidases; Cells, Cultured; Cerebellum; Female; Gene Expression Regulation; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2006 |
Nitric oxide contributes to AT2 but not AT1 angiotensin II receptor-mediated vasodilatation of porcine pial arteries and arterioles.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arteries; Biphenyl Compounds; Enzyme Inhibitors; Female; Imidazoles; Male; Naphthyridines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Pia Mater; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Swine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Constrictor and dilator effects of angiotensin II on cerebral arterioles.
Topics: Angiotensin II; Animals; Arterioles; Benzimidazoles; Benzoates; Calcium Channel Blockers; Captopril; Cerebral Arteries; Dose-Response Relationship, Drug; Imidazoles; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Telmisartan; Tetraethylammonium; Vasoconstriction; Vasodilation | 2005 |
Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation.
Topics: Albumins; Androstadienes; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Fractionation; Cell Line; Chromones; Endocytosis; Imidazoles; Kidney Tubules, Proximal; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 2; Staurosporine; Sus scrofa; Wortmannin | 2005 |
Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cholesterol; Imidazoles; Lipid Metabolism; Liver; Male; Oligopeptides; Olmesartan Medoxomil; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2006 |
The AT1A receptor "gain-of-function" mutant N111S/delta329 is both constitutively active and hyperreactive to angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Cell Line; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Indoles; Inositol Phosphates; Maleimides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Protein Binding; Pyridines; Receptor, Angiotensin, Type 1; Transfection | 2006 |
Biphasic effects of angiotensin II and receptor antagonism on aggregability and protein kinase C phosphorylation in human platelets.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Blood Platelets; Female; Humans; Imidazoles; In Vitro Techniques; Isoenzymes; Male; Middle Aged; Phosphorylation; Platelet Aggregation; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2005 |
Angiotensin II-induced vasodilatation in cerebral arteries is mediated by endothelium-derived hyperpolarising factor.
Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apamin; Benzimidazoles; Biological Factors; Biphenyl Compounds; Cerebral Arteries; Charybdotoxin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Male; Neurotoxins; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.
Topics: Angiotensin Amide; Angiotensin II; Angiotensinogen; Animals; Blotting, Western; Calcium; Cell Line; Cells, Cultured; Fluorometry; Gene Expression Regulation; Glucose; Humans; Imidazoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Nifedipine; Peptidyl-Dipeptidase A; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saralasin | 2006 |
AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arsenicals; Cells, Cultured; Colchicine; Colforsin; Cyclic AMP; Cytoskeleton; Endocytosis; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Kidney Tubules, Proximal; Losartan; Microtubules; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Sucrose | 2006 |
Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Evoked Potentials; Ganglia, Sympathetic; Imidazoles; Indoles; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Neurons; Oxotremorine; Potassium; Potassium Channel Blockers; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tachyphylaxis; Vasoconstrictor Agents | 2006 |
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance.
Topics: Adiponectin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Imidazoles; Injections, Subcutaneous; Insulin; Insulin Resistance; Leptin; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Adiponectin; Receptors, Cell Surface; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Transactivation of the epidermal growth factor receptor by angiotensin II in glomerular podocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Coculture Techniques; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Green Fluorescent Proteins; Heparin-binding EGF-like Growth Factor; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Kidney Glomerulus; Losartan; Metalloproteases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Phosphorylation; Podocytes; Protease Inhibitors; Pyridines; Recombinant Fusion Proteins; Time Factors; Transcriptional Activation | 2006 |
Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.
Topics: Adaptation, Physiological; Amidines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Dinoprostone; Hydroxyeicosatetraenoic Acids; Imidazoles; Indomethacin; Losartan; Male; Microcirculation; Nephrectomy; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Effects of i.c.v. losartan on the angiotensin II-mediated vasopressin release and hypothalamic fos expression in near-term ovine fetuses.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Female; Fetus; Hypothalamus; Imidazoles; Injections, Intraventricular; Losartan; Pregnancy; Proto-Oncogene Proteins c-fos; Pyridines; Sheep; Time Factors; Vasopressins | 2006 |
AT2 receptor-mediated vasodilation in the mouse heart depends on AT1A receptor activation.
Topics: Angiotensin II; Animals; Coronary Circulation; Imidazoles; Male; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation | 2006 |
Angiotensin II disrupts inhibitory avoidance memory retrieval.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anxiety; Avoidance Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Imidazoles; Losartan; Male; Memory; Motor Activity; Pyridines; Rats; Rats, Wistar | 2006 |
Biphasic actions of angiotensin IV on renal blood flow in the rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Kidney; Losartan; Male; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regional Blood Flow; Vasodilator Agents | 2006 |
Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro.
Topics: Adrenergic Antagonists; Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atropine; Blotting, Western; Cholinergic Antagonists; Dose-Response Relationship, Drug; Female; Guanethidine; Humans; Imidazoles; In Vitro Techniques; Intestine, Small; Losartan; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Species Specificity | 2006 |
Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.
Topics: Angiotensin II; Atherosclerosis; Cathepsin F; Cathepsins; Cell Survival; Humans; Imidazoles; Losartan; Macrophages; Pyridines; Receptor, Angiotensin, Type 2 | 2007 |
Translocation of AT1- and AT2-receptors by higher concentrations of angiotensin II in the smooth muscle cells of rat internal anal sphincter.
Topics: Anal Canal; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biotin; Blotting, Western; Cytosol; Fluorescent Antibody Technique; Imidazoles; In Vitro Techniques; Losartan; Male; Microscopy, Confocal; Muscle, Smooth; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; Translocation, Genetic | 2006 |
Angiotensin II regulates extraneuronal dopamine uptake in the kidney.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dopamine; Dose-Response Relationship, Drug; Hydrocortisone; Imidazoles; In Vitro Techniques; Kidney; Kidney Tubules, Proximal; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium; Temperature; Time Factors | 2006 |
The role of angiotensin II in stress urinary incontinence: A rat model.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Disease Models, Animal; Female; Imidazoles; Losartan; Peripheral Nerve Injuries; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Urethra; Urinary Bladder; Urinary Incontinence, Stress; Vasoconstrictor Agents | 2007 |
Ang II and Ang III modulate PTZ seizure threshold in non-stressed and stressed mice: possible involvement of noradrenergic mechanism.
Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin III; Animals; Convulsants; Desipramine; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Mice; Mice, Inbred ICR; Norepinephrine; Pentylenetetrazole; Pyridines; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Restraint, Physical; Seizures; Stress, Psychological; Sympathetic Nervous System | 2006 |
Systemic and renal hemodynamic effects of the AT1 receptor antagonist, ZD 7155, and the AT2 receptor antagonist, PD 123319, in conscious lambs.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Animals, Newborn; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Imidazoles; Kidney; Naphthyridines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Sheep; Time Factors; Vascular Resistance | 2007 |
Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes.
Topics: Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensins; Cell Differentiation; Gene Expression; Humans; Imidazoles; Mesenchymal Stem Cells; Pyridines; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2006 |
Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Carrier Proteins; Cell Differentiation; Cell Nucleus; Cells, Cultured; DNA Repair; Imidazoles; Inhibitor of Differentiation Protein 1; Ligases; Mice; Nerve Tissue Proteins; Neurites; Neurons; Oligopeptides; Protein Phosphatase 1; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Signal Transduction; Synapses; Tetrazoles; Transcriptional Activation; Tumor Suppressor Proteins; Valine; Valsartan; Vanadates | 2007 |
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Genetic Vectors; Hypertension; Imidazoles; Losartan; Male; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Time Factors; Transduction, Genetic; Up-Regulation | 2007 |
Angiotensin II regulates migration in mouse cultured mesangial cells: evidence for the presence of receptor subtype-specific regulation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cell Movement; Cell Proliferation; Cells, Cultured; Imidazoles; Immunoblotting; Mesangial Cells; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2006 |
Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism.
Topics: Anesthesia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Benzazepines; Diuresis; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Fenoldopam; Imidazoles; Kidney; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Dopamine D1; Sodium, Dietary | 2007 |
[Alteration of signal transduction-associated gene expression in rat cardiac fibroblasts induced by blocking angiotensin II receptors].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Fibroblasts; Gene Expression; Imidazoles; Losartan; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction | 2006 |
Angiotensin II-induced genomic damage in renal cells can be prevented by angiotensin II type 1 receptor blockage or radical scavenging.
Topics: Acetylcysteine; alpha-Tocopherol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Cell Nucleus; Comet Assay; DNA Damage; Dose-Response Relationship, Drug; Flow Cytometry; Free Radical Scavengers; Humans; Imidazoles; Kidney; Pyridines; Rats; Reactive Oxygen Species; Swine; Tetrazoles | 2007 |
Regulation of cGMP synthesis in cultured podocytes by vasoactive hormones.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Imidazoles; Nitric Oxide Donors; Podocytes; Pyridines; Radioimmunoassay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; S-Nitroso-N-Acetylpenicillamine; Saralasin | 2006 |
Angiotensin II type 2 receptor decreases ischemia reperfusion induced fluid leak.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antimetabolites; Body Fluids; Capillary Permeability; Cyclic AMP; Dideoxyadenosine; Female; Imidazoles; Oxygen; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Reperfusion Injury; Vasoconstrictor Agents; Venules | 2007 |
Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Line, Tumor; Chemokine CCL2; Diabetes Mellitus, Type 1; Gene Expression; Hyperglycemia; Imidazoles; Insulin-Secreting Cells; Insulinoma; Interleukin-1beta; Losartan; Mice; Mice, Inbred NOD; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Pyridines; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstrictor Agents | 2007 |
Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Binding, Competitive; Brain; Drug Interactions; Imidazoles; Iodine Isotopes; Losartan; p-Chloromercuribenzoic Acid; Pyridines; Rats; Rats, Sprague-Dawley | 2007 |
Angiotensin II mediates postischemic leukocyte-endothelial interactions: role of calcitonin gene-related peptide.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Cell Adhesion; Chymases; Disease Models, Animal; Endothelial Cells; Imidazoles; Intestines; Ischemia; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; NADPH Oxidases; Pyridines; Pyrimidinones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Calcitonin Gene-Related Peptide; Reperfusion Injury; Tetrazoles; Valine; Valsartan; Venules | 2007 |
Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Arsenicals; Biphenyl Compounds; Blotting, Western; Caspase 3; DNA Fragmentation; Flow Cytometry; Fluorescent Antibody Technique; Imidazoles; Irbesartan; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Tetrazoles; Transfection | 2007 |
17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Estradiol; Estrogen Antagonists; Fibroblasts; Fulvestrant; Heart; Imidazoles; Indicators and Reagents; Losartan; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
On the mechanism of coronary vasodilation induced by angiotensin-(1-7) in the isolated guinea pig heart.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Bradykinin; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Vasodilation | 2007 |
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.
Topics: Acetophenones; Allopurinol; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Drug Antagonism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Onium Compounds; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxides | 2007 |
Evidence for a role of AT(2) receptors at the CVLM in the cardiovascular changes induced by low-intensity physical activity in renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Bradycardia; Heart Rate; Hypertension, Renovascular; Imidazoles; Medulla Oblongata; Microinjections; Neurons; Physical Conditioning, Animal; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sympathetic Nervous System | 2007 |
Role of NADPH oxidase and ANG II in diabetes-induced retinal leukostasis.
Topics: Acetophenones; Acetylcysteine; Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Imidazoles; Indoles; Leukostasis; Losartan; Male; NADPH Oxidases; Pyridines; Pyrroles; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retinal Diseases; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2007 |
Role of the angiotensin II type-2 receptor in radiation nephropathy.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Humans; Imidazoles; Kidney Diseases; Male; Mice; Pyridines; Radiation Injuries, Experimental; Rats; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors | 2007 |
Arterial stiffness and haemodynamic response to vasoactive medication in subjects with insulin-resistance syndrome.
Topics: Adult; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Arteries; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Imidazoles; Insulin Resistance; Male; Middle Aged; Nitroglycerin; omega-N-Methylarginine; Photoplethysmography; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance; Vasoconstrictor Agents | 2008 |
Angiotensin II receptor blocker inhibits neointimal hyperplasia through regulation of smooth muscle-like progenitor cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Femoral Artery; Humans; Imidazoles; Mice; Mice, Transgenic; Myocytes, Smooth Muscle; Peripheral Vascular Diseases; Pyridines | 2007 |
Angiotensin II receptors subtypes mediate diverse gene expression profile in adult hypertrophic cardiomyocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Imidazoles; Interleukin-1beta; Interleukin-6; Ligation; Losartan; Male; Myocytes, Cardiac; Oligonucleotide Array Sequence Analysis; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2007 |
Angiotensin II induces capillary formation from endothelial cells via the LOX-1 dependent redox-sensitive pathway.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Capillaries; Cells, Cultured; Coronary Vessels; Endothelial Cells; Feedback, Physiological; Humans; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Transgenic; Organ Culture Techniques; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; Scavenger Receptors, Class E; Signal Transduction; Vascular Endothelial Growth Factor A | 2007 |
Angiotensin II protects against alpha-synuclein toxicity and reduces protein aggregation in vitro.
Topics: alpha-Synuclein; Angiotensin II; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Immunoblotting; Inclusion Bodies; Losartan; Parkinson Disease; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstrictor Agents | 2007 |
The effect of angiotensin II and IV on ERK1/2 and CREB signalling in cultured rat astroglial cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Apoptosis; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Pyridines; Rats; Receptors, Angiotensin; Vasoconstrictor Agents | 2007 |
Negative inotropic effect of selective AT2 receptor stimulation and its modulation by the endocardial endothelium.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apamin; Bradykinin; Cardiovascular Agents; Charybdotoxin; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Endocardium; Endothelial Cells; Enzyme Inhibitors; Hydroxocobalamin; Imidazoles; In Vitro Techniques; Indomethacin; Myocardial Contraction; Naphthyridines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Papillary Muscles; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Proadifen; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Time Factors | 2008 |
The role of angiotensin II in the early stages of bovine ovulation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Cattle; Female; Gonadotropin-Releasing Hormone; Imidazoles; Injections; Losartan; Luteinizing Hormone; Ovarian Follicle; Ovulation; Pyridines; Random Allocation; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Saralasin; Ultrasonography | 2007 |
Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Losartan; Neovascularization, Physiologic; Peptide Fragments; Pyridines; Receptors, Angiotensin; Umbilical Veins; Vasoconstrictor Agents | 2007 |
Angiotensin II induces vascular endothelial growth factor in pancreatic cancer cells through an angiotensin II type 1 receptor and ERK1/2 signaling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Disease Progression; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Genistein; Humans; Imidazoles; Immunohistochemistry; Losartan; Mitogen-Activated Protein Kinase 1; Neovascularization, Pathologic; Pancreatic Neoplasms; Protein Kinase Inhibitors; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Signal Transduction; Vascular Endothelial Growth Factor A; Vasoconstrictor Agents | 2008 |
Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Oligopeptides; Phentolamine; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Nitrite; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Role of the renin angiotensin system in TNF-alpha and Shiga-toxin-induced tissue factor expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Enalapril; Endothelium, Vascular; Humans; Imidazoles; Kidney Glomerulus; Losartan; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Shiga Toxin 1; Thromboplastin; Tumor Necrosis Factor-alpha; Up-Regulation | 2008 |
Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Dose-Response Relationship, Drug; Imidazoles; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Vascular Resistance; Vasoconstrictor Agents | 2008 |
Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; CD13 Antigens; Drug Synergism; Female; Glutamyl Aminopeptidase; Imidazoles; Kidney; Methionine; Natriuresis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sodium, Dietary; Sulfonic Acids; Tetrazoles | 2008 |
Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Enalaprilat; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension, Renovascular; Imidazoles; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Partial Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Surgical Instruments; Tetrazoles; Vascular Resistance | 2008 |
[Association between murine double minute 2 expression and AngII and ceramide induced endothelial cells apoptosis].
Topics: Angiotensin II; Apoptosis; Cells, Cultured; Endothelial Cells; Gene Expression; Humans; Imidazoles; Proto-Oncogene Proteins c-mdm2; Pyridines; RNA, Messenger; Sphingosine; Umbilical Veins | 2007 |
Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Imidazoles; Injections; Intraocular Pressure; Male; Oligopeptides; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Tonometry, Ocular; Vitreous Body | 2008 |
Prenatal gender-related nicotine exposure increases blood pressure response to angiotensin II in adult offspring.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium; Enzyme Inhibitors; Female; Imidazoles; Losartan; Mesenteric Arteries; Nicotine; Nicotinic Agonists; Nitroarginine; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sex Characteristics; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells.
Topics: ADP-ribosyl Cyclase; Angiotensin II; Animals; Calcium; Cell Division; Cyclic ADP-Ribose; Glomerular Mesangium; Imidazoles; Kinetics; Mice; Pyridines; Vasoconstrictor Agents | 2008 |
Angiotensin II upregulates LDL receptor-related protein (LRP1) expression in the vascular wall: a new pro-atherogenic mechanism of hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Atherosclerosis; Cells, Cultured; Cholesterol Esters; Disease Models, Animal; Humans; Hypertension; Imidazoles; Lactoferrin; Losartan; Low Density Lipoprotein Receptor-Related Protein-1; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Up-Regulation | 2008 |
Angiotensin IV-evoked vasoprotection is conserved in advanced atheroma.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Diet, Atherogenic; Disease Models, Animal; Endothelial Cells; Imidazoles; Male; Mice; Mice, Knockout; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyridines; Receptors, Angiotensin; Superoxides; Up-Regulation | 2008 |
Angiotensin II type 2 receptor stimulation increases the rate of NG108-15 cell migration via actin depolymerization.
Topics: Actins; Angiotensin II; Animals; Cell Line, Tumor; Cell Movement; Cofilin 1; Imidazoles; Kinetics; Mice; Neuroblastoma; Phosphoric Monoester Hydrolases; Pyridines; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection | 2008 |
Coronary constriction to angiotensin II is enhanced by endothelial superoxide production in sheep programmed by dexamethasone.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Coronary Vessels; Dexamethasone; Endothelium, Vascular; Female; Glucocorticoids; Imidazoles; Losartan; NADP; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Sheep; Superoxides; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Analysis of the vasorelaxant action of angiotensin II in the isolated rat renal artery.
Topics: Angiotensin II; Animals; Bradykinin; Imidazoles; In Vitro Techniques; Male; Nitroarginine; Pyridines; Rats; Rats, Wistar; Renal Artery; Vasodilation | 2008 |
Angiotensin II type 1 receptor antagonist improves the prognosis in rats displaying liver cirrhosis induced by a choline-deficient diet.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Choline; Disease Models, Animal; Imidazoles; Lipid Peroxidation; Liver Cirrhosis; Male; Pyridines; Rats; Rats, Inbred F344; Tetrazoles; Vasoconstrictor Agents | 2008 |
Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats.
Topics: Aging; Angiotensin II; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Arteries; Cattle; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Inhibition of Angiotensin II receptors during pregnancy induces malformations in developing rat kidney.
Topics: Abnormalities, Drug-Induced; Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Animals, Newborn; Autoradiography; Female; Imidazoles; Kidney; Kidney Glomerulus; Losartan; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2008 |
Effects of angiotensin II and its metabolites in the rat coronary vascular bed: is angiotensin III the preferred ligand of the angiotensin AT2 receptor?
Topics: Angiotensin II; Angiotensin III; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Ligands; Male; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Vasoconstriction | 2008 |
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents | 2008 |
Regulation of renal 12(S)-hydroxyeicosatetraenoic acid in diabetes by angiotensin AT1 and AT2 receptors.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hypoglycemic Agents; Imidazoles; In Vitro Techniques; Insulin; Kidney; Male; Microdialysis; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan | 2008 |
Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Disease Models, Animal; Electric Stimulation; Hypertension; Imidazoles; Mesenteric Arteries; Neuropeptide Y; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Splanchnic Circulation; Sympathetic Nervous System | 2008 |
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation | 2009 |
Regulation of T-cell function by endogenously produced angiotensin II.
Topics: Adoptive Transfer; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Autocrine Communication; Blood Pressure; Catalase; Cells, Cultured; Homeodomain Proteins; Imidazoles; Infusion Pumps, Implantable; Losartan; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Polyethylene Glycols; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Superoxide Dismutase; Superoxides; T-Lymphocytes; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phenylephrine; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Effect of angiotensin II and bradykinin inhibition in rat reduced-size liver transplantation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Flow Velocity; Bradykinin; Hepatic Artery; Imidazoles; Liver; Liver Circulation; Liver Transplantation; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Portal Vein; Proliferating Cell Nuclear Antigen; Pyridines; Rats; Regeneration; RNA, Messenger | 2009 |
Ang-(3-4) suppresses inhibition of renal plasma membrane calcium pump by Ang II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Transporting ATPases; Cell Membrane; Chromatography, High Pressure Liquid; Enzyme Activation; Imidazoles; In Vitro Techniques; Kidney; Oligopeptides; Peptide Fragments; Pyridines; Receptors, Angiotensin; Sheep; Spectrometry, Mass, Electrospray Ionization; Vasoconstrictor Agents | 2009 |
Angiotensin II type-2 (AT2) receptor antagonism alters cardiovascular responses to static exercise and simultaneously changes glutamate/GABA levels within the ventrolateral medulla.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Extracellular Fluid; Female; gamma-Aminobutyric Acid; Glutamic Acid; Imidazoles; Medulla Oblongata; Microdialysis; Muscle Contraction; Physical Conditioning, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reticular Formation; Synaptic Transmission; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Cross talk between kinin and angiotensin II receptors in mouse abdominal aorta.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Bradykinin; Imidazoles; Kinins; Mice; Mice, Inbred BALB C; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Polymerase Chain Reaction; Pyridines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Angiotensin; Vasodilator Agents | 2009 |
Conditional expression of type 2 angiotensin II receptor in rat vascular smooth muscle cells reveals the interplay of the angiotensin system in matrix metalloproteinase 2 expression and vascular remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Endothelium, Vascular; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Pyridines; Rats; Receptor, Angiotensin, Type 2; Signal Transduction; Tetrazoles | 2009 |
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.
Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Down-Regulation; Female; Gene Expression; Humans; Imidazoles; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stereoisomerism; Uterus | 2009 |
Acute modulation of myocardial function by angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Diastole; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Male; Myocardial Contraction; Naphthyridines; Nitroarginine; Papillary Muscles; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rabbits; Receptors, G-Protein-Coupled | 2009 |
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease.
Topics: Aged; Angina Pectoris; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Arteries; Blotting, Western; Case-Control Studies; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelin-1; Humans; Imidazoles; Immunohistochemistry; Middle Aged; Muscle, Smooth, Vascular; Myocardial Ischemia; Myography; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Subcutaneous Tissue; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2009 |
Angiotensin II activates JAK2/STAT3 pathway and induces interleukin-6 production in cultured rat brainstem astrocytes.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Astrocytes; Brain Stem; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Imidazoles; Interleukin-6; Janus Kinase 2; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; STAT3 Transcription Factor; Time Factors; Tyrphostins; Vasoconstrictor Agents | 2010 |
Angiotensin II receptors are expressed and functional in human esophageal mucosa.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Benzimidazoles; Biopsy; Biphenyl Compounds; Blood Vessels; Electric Impedance; Electrophysiological Phenomena; Epithelial Cells; Esophagus; Female; Gene Expression; Humans; Hydrochloric Acid; Imidazoles; Losartan; Male; Middle Aged; Mucous Membrane; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2009 |
[Role of angiotensin II and JAK2 signal pathway in transdifferentation of renal tubular cells in mice after acute ischemic followed by reperfusion].
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Imidazoles; Janus Kinase 2; Kidney Tubules; Male; Pyridines; Rats; Rats, Wistar; Renin-Angiotensin System; Reperfusion Injury; RNA, Messenger; Signal Transduction; Tyrphostins | 2009 |
Angiotensin II effects on ischemic focal ventricular tachycardia are predominantly mediated through myocardial AT(2) receptor.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Electrophysiologic Techniques, Cardiac; Endocardium; Female; Imidazoles; Infusions, Intravenous; Losartan; Male; Myocardial Ischemia; Myocardium; Purkinje Fibers; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tachycardia, Ventricular; Time Factors | 2009 |
Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Bartter Syndrome; Cells, Cultured; Drug Combinations; Dual Specificity Phosphatase 1; Female; Fibroblasts; Gitelman Syndrome; Humans; Hypertension; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2010 |
Effect of acute stress on sexual behavior in female rats: participation of the central angiotensinergic system.
Topics: Acute Disease; Amygdala; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Female; Imidazoles; Losartan; Motor Activity; Oocytes; Proestrus; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Restraint, Physical; Sexual Behavior, Animal; Stress, Psychological; Time Factors | 2010 |
Angiotensin II exerts glucose-dependent effects on Kv currents in mouse pancreatic beta-cells via angiotensin II type 2 receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Glucose; Imidazoles; Insulin; Insulin-Secreting Cells; Ion Channel Gating; Losartan; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Potassium; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Shab Potassium Channels; Signal Transduction; Time Factors | 2010 |
Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Enzyme Inhibitors; Female; Imidazoles; Kidney Cortex; Leucine; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Reactive Oxygen Species; Receptors, Angiotensin; Sheep; Time Factors | 2010 |
Expressions of inducible nitric oxide synthase and cyclooxygenase-2 in gastric ischemia-reperfusion: role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cyclooxygenase 2; Dinoprostone; Gastritis; Imidazoles; Male; Neutrophils; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Tetrazoles | 2010 |
Angiotensin II-activated protein kinase D mediates acute aldosterone secretion.
Topics: Adenoviridae; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Enzyme Activation; Imidazoles; Mutant Proteins; Potassium; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Tetradecanoylphorbol Acetate; Tetrazoles; Time Factors; Zona Glomerulosa | 2010 |
Angiotensin II type 1 and type 2 receptors regulate basal skeletal muscle microvascular volume and glucose use.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Flow Velocity; Blood Glucose; Blood Pressure Determination; Blood Volume; Disease Models, Animal; Imidazoles; Infusions, Intravenous; Losartan; Male; Microcirculation; Muscle, Skeletal; Probability; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Vasoconstrictor Agents | 2010 |
Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilation.
Topics: Analysis of Variance; Angiotensin II; Angiotensin III; Animals; Aorta, Abdominal; Biphenyl Compounds; Coronary Circulation; Disease Models, Animal; Iliac Artery; Imidazoles; Irbesartan; Male; Probability; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 2; Reference Values; Tetrazoles; Vasoconstriction; Vasodilation | 2010 |
Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Cell Line; Cell Proliferation; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Pyridines; Quinazolines; Rats; Receptors, Angiotensin; Transcriptional Activation; Tyrphostins | 2009 |
Angiotensin II AT2 receptor regulates ureteric bud morphogenesis.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Gene Expression Regulation, Developmental; Gestational Age; Glial Cell Line-Derived Neurotrophic Factor; Imidazoles; Immunohistochemistry; In Situ Hybridization; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphogenesis; Mutation; Oligopeptides; Organ Culture Techniques; Phosphoproteins; Proto-Oncogene Proteins c-ret; Pyridines; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Ureter; Wnt Proteins | 2010 |
Angiotensin type 2 receptor actions contribute to angiotensin type 1 receptor blocker effects on kidney fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Blood Pressure; Cell Proliferation; Cells, Cultured; Chronic Disease; Collagen; Disease Models, Animal; Fibrinolysin; Fibrosis; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nephrectomy; Phosphorylation; Plasminogen Activator Inhibitor 1; Podocytes; Proteinuria; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; RNA, Messenger; Time Factors | 2010 |
Developmental effect of antenatal exposure to betamethasone on renal angiotensin II activity in the young adult sheep.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Betamethasone; Biphenyl Compounds; Blood Pressure; Female; Glomerular Filtration Rate; Glucocorticoids; Imidazoles; Infusions, Intra-Arterial; Kidney; Lithium; Male; Organ Size; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Random Allocation; Renal Blood Flow, Effective; Sheep; Sodium; Tetrazoles; Vascular Resistance | 2010 |
Blockage of angiotensin II type 2 receptor prevents thyroxine-mediated cardiac hypertrophy by blocking Akt activation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Disease Models, Animal; Heart Diseases; Hyperthyroidism; Hypertrophy; Imidazoles; Myocardium; Myocytes, Cardiac; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Thyroxine | 2010 |
[The effect of angiotensin II on phosphoinositide-3 kinase/Akt cascade in cultured fibroblasts derived from patients with hypertrophic scars].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Cells, Cultured; Cicatrix, Hypertrophic; Fibroblasts; Humans; Imidazoles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles; Valine; Valsartan | 2010 |
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2010 |
Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Imidazoles; Losartan; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Vasoconstrictor Agents | 2010 |
Multiple cross talk between angiotensin II, bradykinin, and insulin signaling in the cortical thick ascending limb of rat kidney.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Bradykinin; Bradykinin B2 Receptor Antagonists; Calcium; Imidazoles; In Vitro Techniques; Insulin; Kidney; Male; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction | 2010 |
The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Basigin; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Imidazoles; Losartan; Macrophages; Nitrobenzenes; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Sulfonamides | 2010 |
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitroprusside; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2).
Topics: Angiotensin II; Animals; Female; Gene Expression Regulation; Heterogeneous-Nuclear Ribonucleoprotein K; Hyperglycemia; Imidazoles; Kidney; Kidney Cortex; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Time Factors; Vascular Endothelial Growth Factor A | 2010 |
Angiotensin II enhances connecting tubule glomerular feedback.
Topics: Amiloride; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterioles; Dose-Response Relationship, Drug; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Feedback, Physiological; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Kidney Tubules; Losartan; Microcirculation; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Sodium Channel Blockers; Sodium Chloride; Vasoconstrictor Agents; Vasodilation | 2010 |
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Calcium; Cells, Cultured; Endothelin-1; Fluorescent Antibody Technique; Guanine Nucleotide Exchange Factors; Imidazoles; Immunoblotting; Immunohistochemistry; Lysophospholipids; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyridines; Rats; Rats, Wistar; Serotonin; Signal Transduction; Sphingosine; Telmisartan | 2010 |
AT₁ receptor and NAD(P)H oxidase mediate angiotensin II-stimulated antioxidant enzymes and mitogen-activated protein kinase activity in the rat hypothalamus.
Topics: Acetophenones; Angiotensin II; Animals; Antioxidants; Benzophenanthridines; Catalase; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Glutathione Peroxidase; Hypothalamus; Imidazoles; Injections, Intraventricular; Losartan; Male; NADPH Oxidases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium; Superoxide Dismutase; Water | 2010 |
Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ.
Topics: Acetophenones; Angiotensin II; Animals; Apoptosis; Benzopyrans; Cardiomegaly; Caspase 3; Caspase 9; Cells, Cultured; Endothelin-1; Imidazoles; Insulin-Like Growth Factor I; Mitochondria; Myocytes, Cardiac; Peptides, Cyclic; Protein Kinase C-delta; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Endothelin; Signal Transduction; Triiodothyronine | 2010 |
Involvement of the AT1 receptor in the venoconstriction induced by angiotensin II in both the inferior vena cava and femoral vein.
Topics: Angiotensin II; Animals; Femoral Vein; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Receptor, Angiotensin, Type 1; Vasoconstriction; Vena Cava, Inferior | 2011 |
Co-operative effects of angiotensin II and caerulein in NFκB activation in pancreatic acinar cells in vitro.
Topics: alpha-Amylases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Cell Line; Ceruletide; Enzyme Activation; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Pancreas, Exocrine; Pancreatitis; Pyridines; Rats; Receptor, Angiotensin, Type 1 | 2011 |
Mechanisms related to NO-induced motility in differentiated rat aortic smooth muscle cells.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Movement; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Imidazoles; Insulin; Losartan; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Phosphatidylinositol 3-Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Up-Regulation | 2011 |
Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sleep Apnea Syndromes | 2011 |
Endogenous angiotensin II suppresses stretch-induced ANP secretion via AT1 receptor pathway.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Hypertrophic; Extracellular Fluid; Gene Expression; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Myocardial Contraction; Peptide Fragments; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reflex, Stretch | 2011 |
Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apelin; Captopril; Cells, Cultured; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Losartan; Mice; Perindopril; Pyridines; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger | 2011 |
Gender differences in pressure-natriuresis and renal autoregulation: role of the Angiotensin type 2 receptor.
Topics: Analysis of Variance; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Body Weight; Female; Homeostasis; Humans; Imidazoles; Kidney; Male; Natriuresis; Organ Size; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renal Circulation; Sex Factors; Vasoconstrictor Agents | 2011 |
20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.
Topics: Adult; Aged; Amidines; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Platelets; Calcium Channels; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelin-1; Humans; Hydroxyeicosatetraenoic Acids; Imidazoles; Ionophores; Irbesartan; Male; Middle Aged; Neutrophils; Oligopeptides; Peptides, Cyclic; Piperidines; Pyridines; Tetrazoles; Young Adult | 2011 |
A single beta-amino acid substitution to angiotensin II confers AT2 receptor selectivity and vascular function.
Topics: Amino Acid Substitution; Analysis of Variance; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Blood Pressure; Cells, Cultured; Enzyme Inhibitors; HEK293 Cells; Humans; Imidazoles; Male; Mice; NG-Nitroarginine Methyl Ester; Protein Binding; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Vasodilation | 2011 |
Intracellular angiotensin II activates rat myometrium.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arsenicals; Autophagy; Brefeldin A; Calcium Signaling; Carbolines; Cells, Cultured; Egtazic Acid; Endocytosis; Endoplasmic Reticulum; Endosomes; Enzyme Inhibitors; Estrenes; Female; Heparin; Imidazoles; Inositol 1,4,5-Trisphosphate Receptors; Losartan; Lysosomes; Macrocyclic Compounds; Macrolides; Models, Biological; Myometrium; NADP; Oxazoles; Piperazines; Pyridines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ryanodine; Saralasin; Signal Transduction; Sirolimus; Type C Phospholipases; Uterus | 2011 |
Both AT₁ and AT₂ receptors mediate proliferation and migration of porcine vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Vessels; Dose-Response Relationship, Drug; Focal Adhesion Protein-Tyrosine Kinases; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein Kinase Inhibitors; Pyridines; Quinolones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sulfones; Swine; Time Factors | 2011 |
Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Flavonoids; Imidazoles; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley | 2011 |
Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Astrocytes; Benzimidazoles; Biphenyl Compounds; Brain; Brain Chemistry; Cells, Cultured; Dexamethasone; Feedback, Physiological; Imidazoles; Immunohistochemistry; Inositol Phosphates; Liver; Mice; Mice, Inbred C57BL; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazoles | 2011 |
Angiotensin II type 1 receptor, but no type 2 receptor, interferes with the insulin-induced nitric oxide production in HUVECs.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Cells, Cultured; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; JNK Mitogen-Activated Protein Kinases; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Serine; Signal Transduction; Tyrosine | 2011 |
Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Cardiovascular System; Chymases; Heart Rate; Imidazoles; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 2012 |
Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Proliferation; Cells, Cultured; Gene Expression; Humans; Imidazoles; Losartan; Podocytes; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Tumor Necrosis Factor-alpha | 2012 |
Apelin secretion and expression of apelin receptors in 3T3-L1 adipocytes are differentially regulated by angiotensin type 1 and type 2 receptors.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Animals; Apelin; Apelin Receptors; Calcium; Cell Line; Cyclic AMP; Cyclic GMP; Flavonoids; Gene Expression Regulation; Imidazoles; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthyridines; Protein Kinase C; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled | 2012 |
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Losartan; MAP Kinase Signaling System; Mesangial Cells; Microscopy, Confocal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transforming Growth Factor beta1 | 2012 |
Resveratrol attenuates angiotensin II-induced senescence of vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; beta-Galactosidase; Blotting, Western; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Assays; Imidazoles; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Resveratrol; Stilbenes; Tumor Suppressor Protein p53 | 2012 |
Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.
Topics: Allosteric Regulation; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Binding, Competitive; Calcium-Transporting ATPases; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Assays; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Kidney Tubules, Proximal; Losartan; Oligopeptides; Phosphorylation; Protein Binding; Protein Conformation; Pyridines; Receptor, Angiotensin, Type 2; Sheep; Signal Transduction; Transfection | 2012 |
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Female; Imidazoles; Kidney Tubules, Proximal; Models, Animal; Natriuresis; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles | 2012 |
Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Arterial Pressure; Captopril; Chymases; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylethanolamine N-Methyltransferase; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System | 2013 |
Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blotting, Western; Brain; Brain Injury, Chronic; Brain Ischemia; DNA Methylation; Female; Fetal Growth Retardation; Hypoxia, Brain; Imidazoles; Immunohistochemistry; Male; Microscopy, Confocal; Nicotine; Nicotinic Agonists; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2012 |
Sex differences in the renal vascular response to angiotensin II involves the Mas receptor.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Dose-Response Relationship, Drug; Female; Hemodynamics; Imidazoles; Infusions, Intravenous; Kidney; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renal Circulation; Renin-Angiotensin System; Sex Factors; Signal Transduction; Vasoconstriction | 2012 |
Angiotensin II induces apoptosis in intestinal epithelial cells through the AT2 receptor, GATA-6 and the Bax pathway.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Apoptosis; bcl-2-Associated X Protein; Caco-2 Cells; GATA6 Transcription Factor; Gene Expression Regulation; Humans; Imidazoles; Intestinal Mucosa; Pyridines; Receptor, Angiotensin, Type 2 | 2012 |
Implication of multiple signaling pathways in the regulation of angiotensin II induced enhanced expression of Giα proteins in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bucladesine; Calcium; Cell Line; Chelating Agents; Dactinomycin; Drug Interactions; Egtazic Acid; Estrenes; Gallic Acid; Gene Expression Regulation; Genistein; GTP-Binding Protein alpha Subunits, Gi-Go; Imidazoles; Losartan; Nucleic Acid Synthesis Inhibitors; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Rats; Signal Transduction; Type C Phospholipases | 2012 |
Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cerebrovascular Circulation; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2012 |
Similarities and differences between effects of angiotensin III and angiotensin II on human prostate cancer cell migration and proliferation.
Topics: Angiotensin II; Angiotensin III; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Imidazoles; Losartan; Male; Prostatic Neoplasms; Pyridines; Structure-Activity Relationship | 2012 |
Intake of high sucrose during pregnancy altered large-conductance Ca2+-activated K+ channels and vessel tone in offspring's mesenteric arteries.
Topics: Angiotensin II; Animals; Animals, Newborn; Dietary Carbohydrates; Dose-Response Relationship, Drug; Female; Imidazoles; Large-Conductance Calcium-Activated Potassium Channels; Losartan; Membrane Potentials; Mesenteric Arteries; Models, Animal; Muscle, Smooth, Vascular; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sucrose | 2013 |
Effect of angiotensin II on spatial memory, cerebral blood flow, cholinergic neurotransmission, and brain derived neurotrophic factor in rats.
Topics: Acetylcholine; Acetylcholinesterase; Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Brain-Derived Neurotrophic Factor; Cerebrovascular Circulation; Cholinesterase Inhibitors; Donepezil; Hippocampus; Imidazoles; Indans; Male; Melatonin; Memory; Oxidative Stress; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrazoles | 2013 |
Mesangial cells cultured from pregnant rats display reduced reactivity to angiotensin II: the role of relaxin, nitric oxide and AT2 receptor.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Calcium Signaling; Cells, Cultured; Female; Imidazoles; Mesangial Cells; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Receptors, Peptide; Relaxin | 2012 |
Comparative functional properties of two structurally similar selective nonpeptide drug-like ligands for the angiotensin II type-2 (AT(2)) receptor. Effects on neurite outgrowth in NG108-15 cells.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Carbamates; Cell Line, Tumor; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Imidazoles; Indoles; Ligands; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurites; Pyridines; rap1 GTP-Binding Proteins; Rats; Receptor, Angiotensin, Type 2; Sulfonamides; Thiazolidinediones; Thiophenes | 2013 |
Angiotensin II induces the production of MMP-3 and MMP-13 through the MAPK signaling pathways via the AT(1) receptor in osteoblasts.
Topics: Alkaline Phosphatase; Angiotensin II; Animals; Cell Line, Tumor; Cell Proliferation; Gelatin; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Mice; Osteoblasts; Phosphorylation; Plasminogen Activator Inhibitor 1; Plasminogen Activators; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tissue Inhibitor of Metalloproteinases | 2013 |
Angiotensin II promotes differentiation of mouse embryonic stem cells to smooth muscle cells through PI3-kinase signaling pathway and NF-κB.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Differentiation; Cell Line; Collagen; Embryonic Stem Cells; Imidazoles; Losartan; Mice; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Sulfones | 2013 |
[Effects of angiotensin II and its receptor blockers on migration and endothelin-1 expression of rat vascular adventitial fibroblast subpopulations].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Movement; Cells, Cultured; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents | 2012 |
Angiotensin II induces the generation of procoagulant microparticles by human mononuclear cells via an angiotensin type 2 receptor-mediated pathway.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Cell-Derived Microparticles; Humans; Imidazoles; Leukocytes, Mononuclear; Pyridines; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Thromboplastin | 2013 |
Angiotensin III stimulates high stretch-induced ANP secretion via angiotensin type 2 receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Atrial Natriuretic Factor; Dose-Response Relationship, Drug; Heart Atria; Imidazoles; In Vitro Techniques; Infusions, Intravenous; Losartan; Male; Myocardial Contraction; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction | 2013 |
Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Autophagy; Blood Pressure; Brain; Hypertension; Imidazoles; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Angiotensin II's role in sodium lactate-induced panic-like responses in rats with repeated urocortin 1 injections into the basolateral amygdala: amygdalar angiotensin receptors and panic.
Topics: Amygdala; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cholera Toxin; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Heart Rate; Imidazoles; Male; Microinjections; Neural Pathways; Pain; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Lactate; Urocortins | 2013 |
PD123319 augments angiotensin II-induced abdominal aortic aneurysms through an AT2 receptor-independent mechanism.
Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Aortic Aneurysm, Abdominal; Atherosclerosis; Genotype; Imidazoles; Male; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 2 | 2013 |
Angiotensin AT(1)-receptor blockers enhance cardiac responses to parasympathetic nerve stimulation via presynaptic AT(1) receptors in pithed rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradycardia; Electric Stimulation; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Presynaptic; Tetrazoles; Vagus Nerve | 2013 |
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sympathetic Nervous System | 2013 |
Angiotensin AT2 receptor agonist stimulates high stretch induced- ANP secretion via PI3K/NO/sGC/PKG/pathway.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Atrial Pressure; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Guanylate Cyclase; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Nitric Oxide; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Tissue Culture Techniques; Vasodilator Agents | 2013 |
Tumor necrosis factor-α inhibits angiotensin II receptor type 1 expression in dorsal root ganglion neurons via β-catenin signaling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; beta Catenin; Chromans; Dactinomycin; Dose-Response Relationship, Drug; Ganglia, Spinal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Imidazoles; Indoles; Male; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Rats; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha | 2013 |
Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion.
Topics: AMP-Activated Protein Kinases; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiomegaly; Hyperthyroidism; Imidazoles; Male; Myocardial Reperfusion Injury; Myocardium; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thyroxine; Triiodothyronine; Ventricular Pressure | 2013 |
Angiotensin type 2 receptors in the intermediolateral cell column of the spinal cord: negative regulation of sympathetic nerve activity and blood pressure.
Topics: Adrenergic Fibers; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Imidazoles; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Spinal Cord | 2013 |
Angiotensin II produces nociceptive behavior through spinal AT1 receptor-mediated p38 mitogen-activated protein kinase activation in mice.
Topics: Angiotensin II; Animals; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Spinal Cord | 2013 |
Stimulation of ANP by angiotensin-(1-9) via the angiotensin type 2 receptor.
Topics: Algorithms; Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cyclic GMP; Heart Atria; Hemodynamics; Imidazoles; Male; Nitric Oxide; Oncogene Protein v-akt; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction; Stimulation, Chemical | 2013 |
Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Endothelial Cells; Female; Imidazoles; Lipopolysaccharides; Losartan; Nitric Oxide Synthase Type II; Pre-Eclampsia; Pregnancy; Prostaglandins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents | 2013 |
Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Benzimidazoles; Benzoates; Cell Hypoxia; Cell Line; Collagen Type I; Fibroblasts; Gene Expression Regulation; Humans; Imidazoles; Lung; NF-kappa B; Peptidyl-Dipeptidase A; Pyridines; Pyrrolidines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Telmisartan; Thiocarbamates | 2013 |
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart Ventricles; Hemodynamics; Hypertension; Imidazoles; Male; Oxidative Stress; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley | 2014 |
Functional closure of the ductus arteriosus at birth: evidence against an intermediary role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Animals, Newborn; Ductus Arteriosus; Female; Imidazoles; Male; Mice; Mice, Inbred C57BL; Olmesartan Medoxomil; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasodilation | 2014 |
Cell atavistic transition: Paired box 2 re-expression occurs in mature tubular epithelial cells during acute kidney injury and is regulated by Angiotensin II.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Antineoplastic Agents; CD24 Antigen; Cell Line; Epithelial Cells; Gene Expression Regulation; Imidazoles; Janus Kinase 2; Kidney Tubules; PAX2 Transcription Factor; Pyridines; Rats; Reperfusion Injury; Tyrphostins; Vasoconstrictor Agents | 2014 |
Effects of acid challenges on type 2 angiotensin II receptor-sensitive ammonia production by the proximal tubule.
Topics: Acids; Ammonia; Angiotensin II; Animals; Imidazoles; Kidney Tubules, Proximal; Male; Mice; Pyridines; Receptor, Angiotensin, Type 2; Vasoconstrictor Agents | 2014 |
Angiotensin II stimulates fibronectin protein synthesis via a Gβγ/arachidonic acid-dependent pathway.
Topics: Angiotensin II; Animals; Arachidonic Acid; Cells, Cultured; CSK Tyrosine-Protein Kinase; ErbB Receptors; Fibronectins; GTP-Binding Protein beta Subunits; GTP-Binding Protein gamma Subunits; Imidazoles; Kidney Tubules, Proximal; Male; MAP Kinase Signaling System; Models, Animal; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Signal Transduction; src-Family Kinases | 2014 |
Role of reactive oxygen species in angiotensin II: induced receptor activator of nuclear factor-κB ligand expression in mouse osteoblastic cells.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Cytochrome b Group; Dose-Response Relationship, Drug; Imidazoles; Mice; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Osteoblasts; Phosphoproteins; Pyridines; RANK Ligand; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Up-Regulation | 2014 |
Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Line; Endothelin-1; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Up-Regulation; Vasoconstriction | 2014 |
Reduced sensitivity of the renal vasculature to angiotensin II in young rats: the role of the angiotensin type 2 receptor.
Topics: Age Factors; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Dose-Response Relationship, Drug; Gene Expression Regulation, Developmental; Imidazoles; Kidney; Male; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renal Artery; Renal Circulation; RNA, Messenger; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Phosphorylation; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Role of Mas receptor antagonist (A779) on pressure diuresis and natriuresis and renal blood flow in the absence of angiotensin II receptors type 1 and 2 in female and male rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Diuresis; Female; Imidazoles; Kidney; Losartan; Male; Natriuresis; Peptide Fragments; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Circulation; Sex Factors; Vascular Resistance | 2014 |
Selective activation of angiotensin AT2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiovascular Agents; Disease Models, Animal; Fibrosis; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Monocrotaline; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling | 2015 |
Synergistic effect of angiotensin II on vascular endothelial growth factor-A-mediated differentiation of bone marrow-derived mesenchymal stem cells into endothelial cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antigens, CD; Benzimidazoles; Benzoates; Bone Marrow Cells; Cadherins; Cell Differentiation; Drug Synergism; Endothelial Cells; Femur; Imidazoles; Mesenchymal Stem Cells; Microscopy, Fluorescence; Pyridines; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Small Interfering; Swine; Telmisartan; Vascular Endothelial Growth Factor A; von Willebrand Factor | 2015 |
Angiotensin-(1-7) protects against the development of aneurysmal subarachnoid hemorrhage in mice.
Topics: Aneurysm, Ruptured; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Brain; Cerebral Arteries; Cytokines; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 2; RNA, Messenger; Subarachnoid Hemorrhage | 2015 |
Characterization and functions of vascular adventitial fibroblast subpopulations.
Topics: Adventitia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Lineage; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; RNA, Messenger | 2015 |
Angiotensin II exerts dual actions on sodium-glucose transporter 1-mediated transport in the human jejunal mucosa.
Topics: Adult; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Biopsy; Endoscopy, Gastrointestinal; Female; Glucose; Glucose Transporter Type 2; Healthy Volunteers; Humans; Imidazoles; Intestinal Mucosa; Jejunum; Male; Pyridines; Rats; Renin-Angiotensin System; Sodium-Glucose Transporter 1; Young Adult | 2015 |
Losartan reverses the down-expression of long noncoding RNA-NR024118 and Cdkn1c induced by angiotensin II in adult rat cardiac fibroblasts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p57; Down-Regulation; Fibroblasts; Imidazoles; Losartan; Male; Myocardium; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Long Noncoding | 2015 |
Activation of angiotensin II type 1 receptors and contractile activity in human sigmoid colon in vitro.
Topics: Aged; Aged, 80 and over; Angiotensin II; Colon, Sigmoid; Female; Humans; Imidazoles; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2015 |
Maternal High-Fat Diet Causes a Sex-Dependent Increase in AGTR2 Expression and Cardiac Dysfunction in Adult Male Rat Offspring.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cardiomegaly; Diet, High-Fat; Female; Fetal Development; Genetic Predisposition to Disease; Heart Diseases; Imidazoles; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Pregnancy; Prenatal Exposure Delayed Effects; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sex Characteristics | 2015 |
Role of Mas receptor antagonist (A779) in renal hemodynamics in condition of blocked angiotensin II receptors in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Female; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Organ Size; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Wistar; Receptor Cross-Talk; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Regional Blood Flow | 2016 |
Renal effects of angiotensin II in the newborn period: role of type 1 and type 2 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Female; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Glomerulus; Male; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Renin-Angiotensin System; Sheep | 2016 |
Angiotensin II induces interleukin-6 expression in astrocytes: Role of reactive oxygen species and NF-κB.
Topics: Angiotensin II; Animals; Astrocytes; Brain; Female; Gene Expression Regulation; Hydrazones; Imidazoles; Interleukin-6; Losartan; NF-kappa B; Nitroimidazoles; Pyridines; Rats, Inbred SHR; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Time Factors | 2016 |
Endogenous angiotensin II in the paraventricular nucleus regulates arterial pressure during hypotension in rat, a single-unit study.
Topics: Action Potentials; Analysis of Variance; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hemorrhage; Hypotension; Imidazoles; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Wistar; Time Factors | 2017 |
The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats.
Topics: Administration, Intravenous; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Body Fluids; Brain; Enzyme Inhibitors; Heart Rate; Imidazoles; Infusions, Intraventricular; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Receptor, Angiotensin, Type 2; Sodium Chloride; Sympathetic Nervous System | 2017 |
Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice.
Topics: Adiponectin; Adipose Tissue; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Chemokine CCL2; Diabetes Mellitus, Type 2; Humans; Hypertension; Imidazoles; Insulin; Insulin Resistance; Interleukin-6; Losartan; Mice; Mice, Knockout; Pyridines; Receptor, Angiotensin, Type 2; Signal Transduction; Tumor Necrosis Factor-alpha | 2017 |
Prostanoids counterbalance the synergism between endothelin-1 and angiotensin II in mesenteric veins of trained rats.
Topics: Angiotensin II; Animals; Endothelin-1; Femoral Vein; Gene Expression Regulation; Imidazoles; Indomethacin; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Culture Techniques; Physical Conditioning, Animal; Prostaglandins; Pyridines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Vasoconstriction | 2017 |
Reduced anxiety-like behavior in transgenic rats with chronically overproduction of angiotensin-(1-7): Role of the Mas receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Anxiety; Behavior, Animal; Imidazoles; Peptide Fragments; Pyridines; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5-8) injected into the rat ventrolateral periaqueductal gray.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anxiety; Imidazoles; Losartan; Male; Periaqueductal Gray; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1 | 2017 |
Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Diterpenes; Ganglia, Spinal; Imidazoles; Male; Mice; Mice, Knockout; Neuroprotective Agents; Pyridines; Ramipril; Receptor, Angiotensin, Type 2; Sensory Receptor Cells; Small Fiber Neuropathy; Substance P; Tetrazoles | 2017 |
Angiotensin II facilitates GABAergic neurotransmission at postsynaptic sites in rat amygdala neurons.
Topics: Amygdala; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Agents; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Losartan; Male; Mice; Neurotransmitter Agents; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Vasoconstrictor Agents | 2018 |
AT2R (Angiotensin II Type 2 Receptor)-Mediated Regulation of NCC (Na-Cl Cotransporter) and Renal K Excretion Depends on the K Channel, Kir4.1.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Imidazoles; Ion Transport; Kidney Tubules, Distal; Losartan; Mice; Mice, Knockout; Potassium Channels, Inwardly Rectifying; Pyridines; Receptor, Angiotensin, Type 2; Sodium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 3; Water-Electrolyte Imbalance | 2018 |
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antidepressive Agents; Captopril; Carbazoles; Cells, Cultured; Cerebral Cortex; Enalapril; Hippocampus; Imidazoles; Immobility Response, Tonic; Indole Alkaloids; Losartan; Male; Mice; Microinjections; Prefrontal Cortex; Proto-Oncogene Proteins c-fyn; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptor, trkB; Transcriptional Activation | 2018 |
Angiotensin II Suppresses Rev-erbα Expression in THP-1 Macrophages via the Ang II Type 1 Receptor/Liver X Receptor α Pathway.
Topics: Angiotensin II; Animals; Cell Line; Down-Regulation; Humans; Imidazoles; Liver X Receptors; Macrophages; Matrix Metalloproteinase 9; Mice; Nuclear Receptor Subfamily 1, Group D, Member 1; Pyridines; RAW 264.7 Cells; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Signal Transduction; Valsartan | 2018 |
Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.
Topics: Angiogenesis Inducing Agents; Angiogenic Proteins; Angiotensin II; Gene Expression Regulation; Humans; Imidazoles; Losartan; Neovascularization, Pathologic; NF-kappa B; Proto-Oncogene Mas; Pyridines; Receptor, Angiotensin, Type 1; Transcription Factor RelA; Transcriptional Activation | 2018 |
Pregnancy upregulates angiotensin type 2 receptor expression and increases blood flow in uterine arteries of rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Estradiol; Female; Imidazoles; Pregnancy; Pregnancy, Animal; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regional Blood Flow; Up-Regulation; Uterine Artery; Uterine Contraction; Uterus | 2018 |
Observations of the Effects of Angiotensin II Receptor Blocker on Angiotensin II-Induced Morphological and Mechanical Changes in Renal Tubular Epithelial Cells Using Atomic Force Microscopy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Benzoates; Cadherins; Epithelial Cells; Epithelial-Mesenchymal Transition; Imidazoles; Kidney Tubules, Distal; Microscopy, Atomic Force; Pyridines; Rats; Telmisartan | 2018 |
Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Communication; Cells, Cultured; Female; Ganglia, Spinal; Genes, Reporter; Humans; Hyperalgesia; Imidazoles; Macrophage Activation; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuralgia; Neutrophil Activation; Oxidation-Reduction; Pyridines; Receptor, Angiotensin, Type 2; Sensory Receptor Cells; Skin; Tacrolimus; TRPA1 Cation Channel | 2018 |
Yes-associated protein mediates angiotensin II-induced vascular smooth muscle cell phenotypic modulation and hypertensive vascular remodelling.
Topics: Angiotensin II; Animals; Apoptosis Regulatory Proteins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Imidazoles; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyridines; Rats, Sprague-Dawley; Signal Transduction; Vascular Remodeling; YAP-Signaling Proteins | 2018 |
A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2 signalling pathways.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anthracenes; Bone Marrow Cells; Cell Differentiation; Cell Lineage; Cell Movement; Imidazoles; Janus Kinase 2; Janus Kinases; Keratinocytes; Losartan; Male; MAP Kinase Signaling System; Mesenchymal Stem Cells; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tyrphostins | 2019 |
Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Butadienes; Cell Survival; Cycloheximide; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; Nitriles; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
Topics: Amides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; DNA Methylation; Embryo, Nonmammalian; Fumarates; Humans; Imidazoles; Melanoma; Molecular Targeted Therapy; Neoplasm Metastasis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Xenograft Model Antitumor Assays; Zebrafish | 2019 |
Age-Related Changes in Ang II Receptor Localization and Expression in the Developing Auditory Pathway.
Topics: Age Factors; Angiotensin II; Animals; Auditory Pathways; Autoradiography; Female; Imidazoles; Mesencephalon; Pregnancy; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 1 | 2019 |
Analysis of angiotensin II-Induced rat urinary bladder contractions in the presence of angiotensin II receptors blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Homeostasis; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Wistar; Stress, Mechanical; Urinary Bladder | 2021 |
Angiotensin II triggers autophagy and apoptosis in PC12 cell line: An in vitro Alzheimer's disease model.
Topics: Alzheimer Disease; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Autophagy; Imidazoles; Losartan; Models, Biological; Neurodegenerative Diseases; PC12 Cells; Pyridines; Rats; Receptor, Angiotensin, Type 1 | 2019 |
Alamandine attenuates long‑term hypertension‑induced cardiac fibrosis independent of blood pressure.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen Type I; Collagen Type I, alpha 1 Chain; Fibrosis; Heart Ventricles; Hypertension; Imidazoles; Male; Matrix Metalloproteinase 9; Oligopeptides; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2019 |
Attenuation of Unevoked Mechanical and Cold Pain Hypersensitivities Associated With Experimental Neuropathy in Mice by Angiotensin II Type-2 Receptor Antagonism.
Topics: Analgesia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Behavior, Animal; Cold Temperature; Female; Gait; Ganglia, Spinal; Hyperalgesia; Imidazoles; Male; Mice; Mice, Inbred C57BL; Neuralgia; Pain Management; Pyridines; Receptor, Angiotensin, Type 2 | 2019 |
PD123319, angiotensin II type II receptor antagonist, inhibits oxidative stress and inflammation in 2, 4-dinitrobenzene sulfonic acid-induced colitis in rat and ameliorates colonic contractility.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Colitis; Colon; Dinitrobenzenes; Imidazoles; Inflammation; Male; Oxidative Stress; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2 | 2020 |
Methylation-reprogrammed AGTR1 results in increased vasoconstriction by angiotensin II in human umbilical cord vessel following in vitro fertilization-embryo transfer.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; DNA Methylation; Embryo Transfer; Female; Fertilization in Vitro; Humans; Imidazoles; Losartan; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Umbilical Cord; Vasoconstriction; Vasoconstrictor Agents | 2019 |
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Necroptosis; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction | 2019 |
Effect of angiotensin II and angiotensin-(1-7) on proliferation of stem cells from human dental apical papilla.
Topics: Adolescent; Angiotensin I; Angiotensin II; Cell Proliferation; Cells, Cultured; Dental Papilla; Female; Humans; Imidazoles; Male; MAP Kinase Signaling System; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Stem Cells | 2021 |
Angiotensinergic receptors in the medial amygdaloid nucleus differently modulate behavioral responses in the elevated plus-maze and forced swimming test in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Corticomedial Nuclear Complex; Imidazoles; Losartan; Male; Maze Learning; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Swimming | 2021 |
Angiotensin II Increases HMGB1 Expression in the Myocardium Through AT1 and AT2 Receptors When Under Pressure Overload.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cardiomegaly; Case-Control Studies; Constriction; HMGB1 Protein; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Pyridines; Up-Regulation; Vasoconstrictor Agents | 2021 |