angiotensin ii has been researched along with fasudil in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, YP; Puri, RN; Rattan, S | 1 |
| Bauer, J; Parekh, N | 1 |
| Hasegawa, K; Hayashi, K; Homma, K; Kanda, T; Mitsuhashi, T; Saruta, T; Sugano, N; Takamatsu, I; Tatematsu, S; Wakino, S; Yoshioka, K | 1 |
| Choy, DF; da Cunha, V; Dole, WP; Halks-Miller, M; Johns, A; Li, W; Light, DR; Mahmoudi, M; Martin-McNulty, B; Schroeder, M; Vincelette, J; Wang, YX | 1 |
| da Cunha, V; Deng, GD; Dole, WP; Feng, Q; Halks-Miller, M; Johns, A; Kauser, K; Light, DR; Lu, X; Mahmoudi, M; Martin-McNulty, B; Schirm, S; Schroeder, M; Subramanyam, B; Tseng, JL; Vincelette, J; Wang, YX | 1 |
| Hayashi, K; Homma, K; Kanda, T; Saruta, T; Sugano, N; Wakino, S | 1 |
| Kost, CK; Martin, DS; Song, J | 1 |
| Jalil, JE; Lavandero, S; Ocaranza, MP; Rivera, P | 1 |
| Badejo, AM; Casey, DB; Dhaliwal, JS; Gallen, TB; Greco, AJ; Kadowitz, PJ | 1 |
| Fukumoto, Y; Rashid, M; Seto, M; Shimokawa, H; Tawara, S; Yano, K | 1 |
| Brook, RD; Chen, LC; Mikolaj, M; Rajagopalan, S; Sun, Q; Wang, A; Xu, X; Ying, Z; Yue, P; Zhong, M | 1 |
| Alfarano, C; Cerbai, E; Failli, P; Franchi-Micheli, S; Mannucci, E; Mugelli, A; Raimondi, L | 1 |
| Burger, D; Carter, A; He, Y; Montezano, AC; Nishigaki, N; Touyz, RM | 1 |
| Eguchi, S; Fujigaki, Y; Hishida, A; Suzuki, H; Yamamoto, T | 1 |
| Alexander, BT; Ojeda, NB; Royals, TP | 1 |
| Chen, YC; Du, GH; Fang, LH; Li, L; Niu, ZR; Wang, DS; Yuan, TY; Zhang, HF | 1 |
| Gómez, GI; Sáez, JC; Velarde, V | 1 |
| Dai, F; Guan, H; Liang, X; Qi, Y; Sun, J; Yao, W | 1 |
1 review(s) available for angiotensin ii and fasudil
| Article | Year |
|---|---|
Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Cyclin-Dependent Kinase Inhibitor p27; Disease Models, Animal; Fibrosis; Glomerulosclerosis, Focal Segmental; Hypertension; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Microcirculation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Vasoconstrictor Agents | 2006 |
1 trial(s) available for angiotensin ii and fasudil
| Article | Year |
|---|---|
Importance of Rac1 signaling pathway inhibition in the pleiotropic effects of HMG-CoA reductase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adult; Angiotensin II; Animals; Atorvastatin; Cells, Cultured; Cross-Over Studies; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertrophy, Left Ventricular; Leukocytes; Male; Pravastatin; Pyrroles; Quinolines; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred WKY; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2009 |
16 other study(ies) available for angiotensin ii and fasudil
| Article | Year |
|---|---|
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins | 2002 |
Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Calcium Channel Blockers; Enzyme Inhibitors; Female; Gallic Acid; Indoles; Nifedipine; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Signal Transduction; Staurosporine; Vasoconstrictor Agents | 2003 |
Role of Rho-kinase and p27 in angiotensin II-induced vascular injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; Intracellular Signaling Peptides and Proteins; Macrophages; Male; Mice; Mice, Knockout; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases; Tumor Suppressor Proteins; Tunica Media | 2005 |
Inhibition of Rho-kinase by fasudil attenuated angiotensin II-induced cardiac hypertrophy in apolipoprotein E deficient mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Apolipoproteins E; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Collagen Type III; Coronary Vessels; Dose-Response Relationship, Drug; Fibrosis; Gene Expression; Heart Rate; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Knockout; Myocardium; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; rho-Associated Kinases; RNA, Messenger; Up-Regulation | 2005 |
Fasudil, a Rho-kinase inhibitor, attenuates angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-deficient mice by inhibiting apoptosis and proteolysis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Endothelium, Vascular; Extracellular Matrix; Intracellular Signaling Peptides and Proteins; Mice; Mice, Knockout; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; rho-Associated Kinases | 2005 |
Androgens potentiate renal vascular responses to angiotensin II via amplification of the Rho kinase signaling pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blotting, Western; Carrier Proteins; Enalapril; Enzyme Activation; Hypertension, Renal; Intracellular Signaling Peptides and Proteins; Kidney; Male; Orchiectomy; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Rats; Rats, Mutant Strains; Renal Veins; rho-Associated Kinases; Signal Transduction; Testosterone; Vascular Resistance | 2006 |
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I converting enzyme levels.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta; Blood Pressure; Chemokine CCL2; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Male; Oxidative Stress; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Rats; Rats, Inbred BN; Rats, Inbred Lew; rho-Associated Kinases; RNA, Messenger; Transforming Growth Factor beta1; Ventricular Remodeling | 2007 |
Analysis of pulmonary vasodilator responses to the Rho-kinase inhibitor fasudil in the anesthetized rat.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthesia; Angiotensin II; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Heart Rate; Hypoxia; Injections, Intravenous; Isradipine; Lung; Male; NG-Nitroarginine Methyl Ester; Protein Kinase Inhibitors; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Vascular Resistance; Vasodilator Agents | 2008 |
Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Atmosphere Exposure Chambers; Blood Pressure; Cardiomegaly; Collagen; Disease Models, Animal; Guanine Nucleotide Exchange Factors; Hypertension; Infusion Pumps; Inhalation Exposure; Injections, Intraperitoneal; Male; Matrix Metalloproteinases, Secreted; Mice; Mice, Inbred C57BL; Myocardium; Particulate Matter; Protein Kinase Inhibitors; rho GTP-Binding Proteins; Rho Guanine Nucleotide Exchange Factors; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vasoconstriction; Vasodilation; Ventricular Remodeling | 2009 |
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Biphenyl Compounds; Diabetes Mellitus, Experimental; In Vitro Techniques; Irbesartan; Losartan; Male; Rats; Rats, Wistar; rho-Associated Kinases; Tetrazoles; Up-Regulation; Vasoconstriction | 2009 |
Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Biphenyl Compounds; Blood Pressure; Cell-Derived Microparticles; Cells, Cultured; Endothelial Cells; Hypertrophy, Left Ventricular; Irbesartan; Male; Membrane Microdomains; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; NADPH Oxidases; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase Inhibitors; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Tetrazoles; Vascular Cell Adhesion Molecule-1 | 2011 |
Comparison of ROCK and EGFR activation pathways in the progression of glomerular injuries in AngII-infused rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Disease Progression; ErbB Receptors; Gefitinib; Kidney Diseases; Kidney Glomerulus; Male; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction | 2011 |
Sex differences in the enhanced responsiveness to acute angiotensin II in growth-restricted rats: role of fasudil, a Rho kinase inhibitor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Blood Pressure; Castration; Enalapril; Female; Fetal Growth Retardation; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Placental Insufficiency; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Renal Circulation; Renin-Angiotensin System; rho-Associated Kinases; Sex Characteristics; Vascular Resistance | 2013 |
Fasudil evokes vasodilatation of rat mesenteric vascular bed via Ca(2+) channels and Rho/ROCK pathway.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Calcium Channels; Dose-Response Relationship, Drug; Endothelium, Vascular; Male; Mesenteric Arteries; Myosin Light Chains; Phosphorylation; Potassium Chloride; Protein Phosphatase 1; Rats; rho-Associated Kinases; Vasodilation | 2016 |
Role of a RhoA/ROCK-Dependent Pathway on Renal Connexin43 Regulation in the Angiotensin II-Induced Renal Damage.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Connexin 43; Creatinine; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; Oxidative Stress; Rats; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Time Factors | 2019 |
RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Dedifferentiation; Cell Line; Cell Movement; Gene Expression Regulation; Humans; Irbesartan; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polymerization; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 1; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Vasodilator Agents | 2020 |