angiotensin ii has been researched along with endothelin-1 in 727 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 158 (21.73) | 18.2507 |
| 2000's | 366 (50.34) | 29.6817 |
| 2010's | 174 (23.93) | 24.3611 |
| 2020's | 29 (3.99) | 2.80 |
| Authors | Studies |
|---|---|
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Emori, T; Hirata, Y; Imai, T; Marumo, F; Masaki, T; Yanagisawa, M | 1 |
| de Nanteuil, G; Laubie, M; Mennecier, P; Merceron, D; Simonet, S; Verbeuren, TJ; Vincent, M | 1 |
| Chua, BH; Chua, CC; Diglio, CA; Siu, BB | 1 |
| Eguchi, S; Hirata, Y; Kanno, K; Kano, H | 1 |
| Benatti, L; Fabbrini, MS; Patrono, C | 1 |
| Czachurski, J; Seller, H; Zanzinger, J | 1 |
| Fareh, J; Larivière, R; Schiffrin, EL; Thibault, G; Tolloczko, B; Touyz, RM | 1 |
| Bie, P; Sandgaard, NC | 1 |
| Gottardo, G; Mazzocchi, G; Meneghelli, V; Nussdorfer, GG; Rebuffat, P | 1 |
| de Nucci, G; Fujihara, CK; Mattar, AL; Ribeiro, MO; Zatz, R | 1 |
| Fareh, J; Schiffrin, EL; Thibault, G; Touyz, RM | 1 |
| Balakrishnan, SM; Gopalakrishnan, V; McNeill, JR; Wang, HD; Wilson, TW | 1 |
| Carayon, A; Grenier, O; Guerot, C; Isnard, R; Kalotka, H; Komajda, M; Lechat, P; Maistre, G; Pousset, F; Thomas, D | 1 |
| Berrino, L; D'Amico, M; di Filippo, C; Rossi, F | 1 |
| Komuro, I; Kurihara, H; Kurihara, Y; Yamazaki, T; Yazaki, Y | 1 |
| Endoh, M; Fujita, S | 1 |
| Cameron, LA; Hinson, JP; Kapas, S; Puddefoot, JR | 2 |
| Aikawa, R; Hiroi, Y; Komuro, I; Kudoh, S; Mizuno, T; Shiojima, I; Yamazaki, T; Yazaki, Y; Zou, Y | 1 |
| Ercan, ZS; Hodoglugil, U; Sipahi, E; Türker, RK | 1 |
| Horie, M; James, AF; Obayashi, K; Sasayama, S; Xie, LH | 1 |
| Leskinen, H; Ruskoaho, H; Vuolteenaho, O | 1 |
| Abe, K; Jiang, ZL; Johnston, CI; Kamimoto, M; Kanazawa, M; Kohzuki, M; Sato, T; Wu, XM; Yasujima, M; Yoshida, K | 1 |
| Barry, WH; Ito, N; Kagaya, Y; Lorell, BH; Weinberg, EO | 1 |
| Cervar, M; Desoye, G; Kainer, F; Nelson, DM | 1 |
| Ganten, D; Lang, MG; Lüscher, TF; Noll, G; Tschudi, MR | 1 |
| Cartledge, WA; Kumar, R; Lincoln, TM; Pandey, KN | 1 |
| Barton, M; d'Uscio, LV; Lüscher, TF; Moreau, P; Shaw, S; Takase, H | 1 |
| Ardaillou, R; Chatziantoniou, C; Dussaule, JC; Essig, M; Vandermeersch, S | 1 |
| Yamazaki, T; Yazaki, Y | 2 |
| Boddi, M; Modesti, PA; Neri Serneri, GG | 1 |
| Alali, A; Balligand, JL; de Zengotita, J; DeUgarte, D; Fischer, TA; Gadbut, AP; Kelly, RA; Kifor, I; Lee, MA; Singh, K; Smith, TW; Ungureanu-Longrois, D | 1 |
| He, GW; Yang, CQ | 2 |
| Diéguez, G; Fernández, N; García, JL; García-Villalón, AL; Gómez, B; Monge, L; Padilla, J | 1 |
| Becker, K; Brodde, OE; Heinroth-Hoffmann, I; Pönicke, K | 1 |
| Dirnberger, E; Dorner, GT; Eichler, HG; Jilma, B; Kapiotis, S; Krejcy, K; Wagner, OF | 1 |
| Brozovich, F; Fisher, SA; Ikebe, M | 1 |
| Nabel, EG; Paul, M; San, H; Schott, E; Tostes, RC; Webb, RC | 1 |
| Fukamizu, A; Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Mizuno, K; Murakami, K; Nyui, N; Ochiai, H; Ohno, S; Tamura, K; Umemura, S; Yabana, M | 1 |
| Hampton, T; Li, J; Morgan, JP; Simons, M | 1 |
| Guan, B; Li, H; Pu, Y; Sun, M; Zeng, Z | 1 |
| Drexler, H; Ling, BN; Marrero, MB; Schieffer, B | 1 |
| Borthayre, A; Giaid, A; Haleen, S; Harrison, DG; Keiser, J; Kurz, S; Laursen, JB; Rajagopalan, S | 1 |
| Myers, PR; Rizvi, MA | 1 |
| Arai, M; Iso, T; Kogure, K; Nagai, R; Suzuki, T; Wada, A | 1 |
| Balazy, M; McGiff, JC; Oyekan, A | 1 |
| Abernethy, DR; Andrawis, NS; Jarrell, ST; Li, X; Preuss, HG; Shi, SJ | 1 |
| Danser, AH; Lamers, JM; Saxena, PR; Schalekamp, MA; van Heugten, HA; van Kesteren, CA | 1 |
| Bezstarosti, K; Dekkers, DH; Eskildsen-Helmond, YE; Lamers, JM; van Heugten, HA | 1 |
| Lüscher, TF; Ruschitzka, FT | 1 |
| Carmines, PK; Didion, SP; Ikenaga, H; Mayhan, WG | 1 |
| Barton, M; d'Uscio, LV; Lüscher, TF; Moreau, P; Shaw, S | 2 |
| Mertes, PM | 1 |
| Bonhomme, G; Katzur, AC; Lachowicz, A; Stojilkovic, SS; Van Goor, F | 1 |
| Allen-Mersh, TG; Carnochan, P; Dworkin, MJ | 1 |
| Browne, AE; Chatterjee, K; Chou, TM; Deedwania, PC; Gao, L; Glantz, SA; Hutchison, SJ; Parmley, WW; Sievers, RE; Sudhir, K; Sun, YP; Zhu, BQ | 1 |
| Harada, M; Igaki, T; Itoh, H; Kuwahara, K; Masuda, I; Miyamoto, Y; Nakagawa, O; Nakao, K; Ogawa, E; Ogawa, Y; Saito, Y; Tanaka, I; Yamashita, J; Yoshimasa, T | 1 |
| Chiou, WJ; Dickinson, R; Opgenorth, TJ; Wu-Wong, JR | 1 |
| Bouriquet, N; Casellas, D; Herizi, A | 1 |
| Bennett, T; Brunner-Ferber, F; Gardiner, SM; Kemp, PA | 1 |
| Peifley, KA; Winkles, JA | 1 |
| Baba, T; Komamura, K; Miyatake, K; Noguchi, T; Ohmori, F; Sasaki, T; Tomimoto, S | 1 |
| Bussières, L; Cernacek, P; Courtemanche, M; Mikes, E; Rouleau, JL; Stewart, D; Talajic, M; Vantrimpont, P; White, M | 1 |
| Dagg, KD; Lipworth, BJ; McKay, IC; McSharry, C; Ramsay, SG; Thomson, NC | 1 |
| Hu, RM; Levin, ER; Morey, AK; Pedram, A; Prins, BA; Razandi, M | 1 |
| Budde, M; Charlon, V; Krum, H; Lacourciere, Y; Viskoper, RJ | 1 |
| Aikawa, R; Komuro, I; Kudoh, S; Nagai, R; Uozumi, H; Yamazaki, T; Yazaki, Y; Zou, Y | 1 |
| Mayhan, WG | 1 |
| Akimoto, K; Herrera, VL; Hirayama, K; Ruiz-Opazo, N | 1 |
| Gharavi, A; Klotman, P | 1 |
| Yanagisawa, H | 1 |
| de Jong, D; de Jong, PA; Delemarre, FM; Didden, MA | 1 |
| Kano, H; Kohno, M; Minami, M; Yasunari, K; Yokokawa, K; Yoshikawa, J | 1 |
| Fukamizu, A; Goto, K; Kobayashi, T; Maeda, S; Maki, S; Miyauchi, T; Murakami, K; Sakai, S; Sugishita, Y; Sugiyama, F; Takata, Y | 1 |
| Gardner, DG; Liang, F | 1 |
| Lüscher, TF; Noll, G; Ruschitzka, FT | 1 |
| Barton, M; d'Uscio, LV; Lüscher, TF; Shaw, S | 1 |
| Champion, HC; Estrada, LN; Estrada, LS; Filep, JG; Kadowitz, PJ | 1 |
| Ferro, CJ; Haynes, WG; Spratt, JC; Webb, DJ | 1 |
| Byers, DM; Cook, HW; Laurin, DE; Palmer, FB | 1 |
| Charlier, AA; Donckier, JE; Heyndrickx, GR; Hodeige, DG; Ketelslegers, JM; Massart, PE; Van Mechelen, H | 1 |
| Aso, T; Bronson, RA; Kubota, T; Maruyama, Y; Shimizu, Y; Yorimitsu, A | 1 |
| Kirton, CA; Loutzenhiser, R | 1 |
| Funk, RH; Hofer, A; Paul, M; Schönfelder, U | 1 |
| Benedetti, G; Benigni, A; Corna, D; Maffi, R; Remuzzi, G; Zoja, C | 1 |
| Kohan, DE | 1 |
| Mélon, P | 1 |
| Boucher, D; Grose, JH; Kingma, I; Larivière, R; Lebel, M | 1 |
| Bonn, D | 1 |
| Kregel, KC; Lewis, SJ; Massett, MP | 1 |
| Brennecke, SP; Gude, NM; King, RG | 1 |
| Duan, J; Xu, W; Yang, N | 1 |
| Baker, KM; Dostal, DE | 1 |
| Boldt, J; Hempelmann, G; Kumle, B; Papsdorf, M; Piper, S | 1 |
| Horio, T; Kangawa, K; Matsuo, H; Nagaya, N; Nishikimi, T; Takishita, S; Yoshihara, F | 1 |
| Amadesi, S; Calò, G; Mascoli, F; Quaglio, D; Regoli, D; Rizzi, A; Vasquez, G; Zamboni, P | 1 |
| Boon, NA; Flapan, AD; Fox, KA; Goodfield, NE; Newby, DE; Webb, DJ | 1 |
| Sasayama, S | 1 |
| Benigni, A; Remuzzi, G | 1 |
| Nodera, M; Shimoguchi, Y; Umemori, Y; Wada, O; Yanagisawa, H | 1 |
| Ardaillou, R; Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Tharaux, PL | 1 |
| Gillespie, DG; Inoue, T; Jackson, EK; Mi, Z | 1 |
| Gray, MO; Kalinyak, JE; Karliner, JS; Li, HT; Long, CS | 1 |
| Frasch, HF; Marshall, BE; Marshall, C | 1 |
| Fujii, M; Hayashi, M; Hisanaga, T; Kinoshita, M; Mabuchi, N; Maeda, K; Ohnishi, M; Sawaki, M; Tsutamoto, T; Wada, A | 1 |
| Cheng, X; Ferrer, P; Molloy, CJ; Pawlowski, JE; Taylor, DS; Wallace, AR | 1 |
| Chalmers, GW; Little, SA; Millar, EA; Shepherd, MC; Thomson, NC | 1 |
| Evans, AM; Kato, K; Kozlowski, RZ | 1 |
| Baldoncini, R; Bellini, C; De Mattia, G; Desideri, G; Ferri, C; Santucci, A; Valenti, M | 1 |
| Li, J; Sun, B; Yu, Z | 1 |
| Aakvaag, A; Djøseland, O; Hall, C; Hystad, M; Karlberg, BE; Kjekshus, J; Klinge, R | 1 |
| Col, V; de Cannière, L; Donckier, J; Messaoudi, L; Michel, L | 1 |
| Nally, JE; Pitt, CM | 1 |
| Hayashi, K; Miyamoto, A | 1 |
| Mitrovic, V; Schönburg, M; Schulz, O; Thormann, J | 1 |
| Chiandussi, L; Mengozzi, G; Mulatero, P; Schena, M; Schiavone, D; Tesio, L; Veglio, F | 1 |
| Ahluwalia, A; Scotland, R; Vallance, P | 1 |
| Alvis, AG; Grassi de Gende, AO; Milesi, V; Rebolledo, A; Rinaldi, GJ | 1 |
| Isoyama, S; Kagaya, Y; Namiuchi, S; Otani, H; Shirato, K; Tanikawa, T | 1 |
| Burrell, CJ; Knightingale, AK; Marshall, AJ | 1 |
| Fukuda, K; Kato, T; Kodama, H; Matsuzaki, J; Ogawa, S; Pan, J; Saito, M; Sano, M; Takahashi, T | 1 |
| Baylis, C; Qiu, C | 1 |
| Nowicki, PT | 1 |
| Arnet, UA; Barton, M; Ganten, D; Lüscher, TF; Noll, G; Novosel, D | 1 |
| Oğütman, C; Ozdem, SS | 1 |
| Bivalacqua, TJ; Champion, HC; D'Souza, FM; Heistad, DD; Hyman, AL; Jeter, JR; Kadowitz, PJ; Ortiz, LA; Toyoda, K | 1 |
| Hagiwara, Y; Ibusuki, T; Kambe, T; Kubo, T; Saito, E | 2 |
| Grohé, C; Neyses, L; Pelzer, T; Shamim, A | 1 |
| Komuro, I; Shiojima, I; Yamazaki, T; Yazaki, Y | 1 |
| Kusano, H; Nishimaru, K; Sekine, T; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| D'Amico, M; Di Filippo, C; Filippelli, A; Rossi, F | 1 |
| Belayet, HM; Kanayama, N; Khatun, S; Kobayashi, T; Sato, E; Terao, T; Tokunaga, N | 1 |
| Aneman, A; Bengtsson, J; Fändriks, L; Holm, M; Pettersson, A; Snygg, J | 1 |
| Sham, JS; Shimoda, LA; Sylvester, JT | 1 |
| Małyszko, J; Myśliwiec, M; Zbroch, E | 1 |
| Campbell, WB; Hanke, CJ; Rosolowsky, LJ | 1 |
| Domínguez, J; García-Escribano, JR; Paule, A; Rodríguez-García, JL; Vázquez, M | 1 |
| D'Amours, M; Grose, JH; Larivière, R; Lebel, M | 1 |
| Bessard, G; Chavanon, O; Devillier, P; Sessa, C; Stanke-Labesque, F; Tripodi, F | 1 |
| Horio, T; Kangawa, K; Matsuo, H; Nishikimi, T; Takishita, S; Yoshihara, F | 1 |
| Acosta, TJ; Berisha, B; Miyamoto, A; Ozawa, T; Sato, K; Schams, D | 1 |
| Fujii, M; Hayashi, M; Hisanaga, T; Horie, H; Kinoshita, M; Mabuchi, N; Maeda, K; Ohnishi, M; Sawaki, M; Sugimoto, Y; Tsutamoto, T; Wada, A | 1 |
| Cleland, JG; Cowburn, PJ; Dargie, HJ; Hillier, C; McGrath, JC; McMurray, JJ; Morton, JJ | 1 |
| Bessard, G; Chavanon, O; Cracowski, JL; Devillier, P; Hunt, M; Sessa, C; Stanke-Labesque, F | 1 |
| Aldashev, AA; Frid, MG; Higashito, R; Nemenoff, RA; Stenmark, KR; Westcott, JY | 1 |
| Fukuda, K; Manabe, T; Nagasaki, K; Ogawa, S; Pan, J; Yamaguchi, K | 1 |
| Gasic, S; Nowotny, P; Ratheiser, K; Vierhapper, H; Wagner, O; Waldhäusl, W | 1 |
| Brunner, F | 1 |
| Eto, T; Imamura, T; Kangawa, K; Kato, J; Kawamoto, M; Kitamura, K; Koiwaya, Y; Kuwasako, K; Tsuji, T; Tsuruda, T | 1 |
| Barg, J; Rosen, B; Zimlichman, R | 1 |
| Barton, M; Carmona, R; d'Uscio, LV; Goettsch, W; Haudenschild, CC; Hillen, H; Krieger, JE; Lattmann, T; Lüscher, TF; Morawietz, H; Münter, K; Shaw, S | 1 |
| Brunton, LL; Endo-Mochizuki, Y; Gonzalez, AM; Meszaros, JG; Villarreal, F; Villegas, S | 1 |
| Bialecki, R; Caccese, R; Graham, A | 1 |
| Andersen, LJ; Bestle, MH; Bie, P; Jensen, TU | 1 |
| Fukamizu, A; Haga, T; Ishida, J; Kimura, S; Moroi, K; Nishiyama, M; Sekiya, S; Shibasaki, T; Usui, H; Zhou, J | 1 |
| Moe, GW; Naik, GO | 1 |
| Kihara, M; Mitsui, Y; Nakasaka, Y; Schmelzer, JD; Takahashi, M | 1 |
| Bohlender, J; Dietz, R; Gerbaulet, S; Gross, M; Kirchengast, M; Krämer, J | 1 |
| Demetriou, D; Watschinger, B; Wenter, C | 1 |
| Boyle, JW; Li, M; Nguyen, HT; Pandey, KN | 1 |
| Dworkin, LD; Feiner, HD; Tolbert, EM; Weisstuch, J | 1 |
| Henrion, D; Lévy, BI; Matrougui, K | 1 |
| Bohlender, J; Hoffmann, B; Kaczmarczyk, G; Wenz, M | 1 |
| Andresen, B; Rizzo, MA; Romero, G; Shome, K; Vasudevan, C | 1 |
| Burke, SE; Cox, BF; Ford, TT; Fu, KI; Lubbers, NL; Nelson, RA; Padley, RJ; Wegner, CD | 1 |
| Doherty, AM; Drimal, D; Drimal, J; Kettmann, V; Mislovicova, M; Moncek, F | 1 |
| Fliegel, L; Moor, AN; Murtazina, R | 1 |
| Russell, A; Watts, S | 1 |
| Moridaira, K; Wada, O; Yanagisawa, H | 1 |
| Acharya, A; Lei, J; Neugarten, J; Silbiger, S | 1 |
| Lüscher, TF | 1 |
| Block, AJ; Isaac, D; Kerut, EK; Pfeffer, MA; Porter, CB; Proulx, G; Qian, C; Rouleau, JL; Sestier, F; Stewart, DJ | 1 |
| Fujikawa, H; Fukazawa, H; Hojo, Y; Ikeda, U; Katsuki, T; Kurosaki, K; Mizuno, O; Shimada, K | 1 |
| Airoldi, F; Alberti, C; Marana, I; Morganti, A; Nador, B; Palatresi, S | 1 |
| Schiffrin, EL | 1 |
| Andreis, PG; Neri, G; Nussdorfer, GG; Pelizzo, MR; Rossi, GP; Sacchetto, A; Tortorella, C | 1 |
| Krum, H | 1 |
| Baba, T; Kanda, T; Kobayashi, I | 1 |
| Bandinelli, B; Bertolozzi, I; Boddi, M; Cecioni, I; Galanti, G; Liguori, P; Modesti, PA; Paniccia, R; Perna, A; Polidori, G; Serneri, GG; Vanni, S | 1 |
| Kelly, RA; Kifor, I; Kusaka, Y; Williams, GH | 1 |
| Maass-Moreno, R; Rothe, CF | 1 |
| Clair, MJ; de Gasparo, M; Hendrick, JW; King, MK; Mandel, J; McElmurray, JH; Mukherjee, R; New, RB; Sampson, AC; Spinale, FG | 1 |
| Fujii, M; Hayashi, M; Horie, H; Kinoshita, M; Mabuchi, N; Maeda, K; Matsumoto, T; Ohnishi, M; Sawaki, M; Sugimoto, Y; Tsutamoto, T; Tsutsui, T; Wada, A | 1 |
| Hong, T; Sun, N; Yang, X; Zhang, R | 1 |
| Andreis, PG; Gottardo, L; Neri, G; Nussdorfer, GG; Tortorella, C | 1 |
| Muscari, A; Puddu, GM; Puddu, P; Zaca, F | 1 |
| Hayashi, K; Iwamoto, K; Kizawa, Y; Kusama, T; Murakami, H; Saito, K; Sano, M | 1 |
| Baba, A; Hashimoto, H; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
| Ardaillou, R; Boffa, JJ; Chatziantoniou, C; Dussaule, JC; Fakhouri, F; Tharaux, PL | 1 |
| Gray, GA; Kenyon, CJ; McEwan, PE; Sherry, L; Webb, DJ | 1 |
| Berg, CE; Kramer, D; Wu-Wong, JR | 1 |
| Jiang, Y; Triggle, CR | 1 |
| Heidbreder, E; Lopau, K; Mark, J; Schramm, L; Wanner, C | 1 |
| Doyle, S; Kurtzberg, L; Ledbetter, S; Pratt, BM | 1 |
| Brown, AJ; Nally, JE | 1 |
| Stocker, SD; Stricker, EM; Sved, AF | 1 |
| Gopalakrishnan, V; McNeill, JR; Quest, DW; Wilson, TW | 1 |
| Harada, M; Hosoya, T; Ikeda, K; Nakao, K; Tojo, K; Tokudome, G | 1 |
| Chiba, S; Fukumori, R; Ibusuki, T; Kambe, T; Kubo, T | 1 |
| Hasegawa, K; Iwai-Kanai, E; Sasayama, S | 1 |
| Ballew, JR; Fink, GD; Watts, SW | 1 |
| Abraham, JA; Damm, D; Garrard, LJ; Henson, M; Joly, AH; Lam, A; Schreiner, GF; Stanton, LW; White, T | 1 |
| Kudo, R; Miyamoto, A; Nishikawa, S; Ohshika, H; Yamamoto, H | 1 |
| Calaghan, SC; White, E | 1 |
| Hara, K; Kobayashi, N; Matsuoka, H; Mori, Y; Nakano, S; Tsubokou, Y | 1 |
| Carrier, GO; Catravas, JD; Dimitropoulou, C; Fuchs, L; White, RE; Zhang, H | 1 |
| Floten, HS; Furnary, AP; He, GW; Liu, MH; Yim, AP | 1 |
| Carretero, OA; Harding, P; LaPointe, MC; Peng, H; Rhaleb, NE; Tayeh, M | 1 |
| Dostal, DE | 1 |
| Cheng, CP; Cheng, HJ; Igawa, A; Little, WC; Ohte, N; Onishi, K; Suzuki, M; Tachibana, H; Ukai, T; Zhang, ZS | 1 |
| Fukamizu, A; Ishida, J; Kimura, S; Moroi, K; Nishiyama, M; Seki, N; Usui, H; Zhou, J | 1 |
| Bescós, M; Campistol, JM; Campos, B; Iñigo, P; Lario, S; Oppenheimer, F; Piera, C; Rivera, F | 1 |
| Boemke, W; Hocher, B; Kaczmarczyk, G; Krebs, MO; Schleyer, N | 1 |
| Alexander, BT; Cockrell, KL; Granger, JP; Herrington, JN; Rinewalt, AN | 1 |
| Egido, J; Fortes, J; Gómez-Garre, D; Largo, R; Manzarbeitia, F; Tejera, N | 1 |
| Vickers, M | 1 |
| Ruwhof, C; Schrier, PI; van der Laarse, A; van der Valk-Kokshoom, LE; van Wamel, AJ | 1 |
| Benedict, CR; Katagiri, T; Pakala, R; Watanabe, T | 1 |
| Bandinelli, B; Bertolozzi, I; Boddi, M; Cecioni, I; Coppo, M; Maccherini, M; Modesti, PA; Papa, ML; Polidori, G; Serneri, GG; Toscano, T; Vanni, S | 1 |
| Asai, K; Kudej, AB; Kudej, RK; Natividad, F; Shen, YT; Takagi, G; Vatner, DE; Vatner, SF | 1 |
| Ma, C; Xu, Y; Zhuang, Y | 1 |
| Guo, X; Luo, A; Wang, M; Xu, S; Zhao, X | 1 |
| Derebail, VK; Pollock, DM; Pollock, JS; Yamamoto, T | 1 |
| Bescos, M; Campistol, JM; Iñigo, P; Larios, S; Oppenheimer, F | 1 |
| Zhan, CD | 1 |
| Komuro, I; Takano, H | 1 |
| Tsui, JK; Wong, NL | 1 |
| Belus, A; Bonnet, S; Hyvelin, JM; Marthan, R; Roux, E; Savineau, JP | 1 |
| Gopalakrishnan, V; Kaul, C; McNeill, JR; Poduri, R; Shastri, S; Wilson, TW | 1 |
| Abitbol, C; Montane, B; Seguias, L; Strauss, J; Zilleruelo, G | 1 |
| Bahlmann, L; Heringlake, M; Klaus, S; Pagel, H; Schmucker, P; Wagner, K | 1 |
| Burnett , JC; Grande, JP; Hart, CY; Housmans, PR; Meyer, DM; Redfield, MM; Tazelaar, HD | 1 |
| Bond, BR; Coker, ML; Etoh, T; Holder, JR; Joffs, C; Jolly, JR; Spinale, FG | 1 |
| Cartier, F; Delarue, C; Do-Rego, JL; Fournier, A; Remy-Jouet, I; Vaudry, H | 1 |
| Liu, JL; Patel, KP; Pliquett, RU; Wang, W; Zucker, IH | 1 |
| Amselgruber, WM; Berisha, B; Kobayashi, S; Miyamoto, A; Schams, D | 1 |
| Inagaki, K; Iwanaga, Y; Kataoka, K; Kihara, Y; Onozawa, Y; Sasayama, S; Yoneda, T | 1 |
| Geng, MY; Guan, HS; Zhang, JT; Zhu, HB | 1 |
| Acosta, TJ; Miyamoto, A; Nishimura, M; Sato, K; Taquahashi, Y; Wijayagunawardane, MP | 1 |
| Bosch, RJ; Egido, J; Esbrit, P; Fernández-Agulló, T; Gazapo, R; Largo, R; Ortega, A; Santos, S | 1 |
| Filippatos, GS; Gangopadhyay, N; Lalude, O; Parameswaran, N; Said, SI; Spielman, W; Uhal, BD | 1 |
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| Dong, WR; Li, ZH; Liu, SM; Lu, F; Yu, H; Zhang, N | 1 |
| Jeong, DW; Kim, HS; Kim, HY | 1 |
| Bramwell, RC; Donato, AJ; Hazra, S; Henson, GD; Lesniewski, LA | 1 |
| Chinen, KT; Donato, AJ; Kronquist, EK; Lesniewski, LA; Li, DY; Reihl, KD; Walker, AE | 1 |
| Bailey, MA; Baudrie, V; Costello, HM; Czopek, A; Dhaun, N; Farrah, T; Guyonnet, L; Kluth, DC; Lenoir, O; Menolascina, F; Moorhouse, R; Owen, E; Tharaux, PL; van Bragt, J; Webb, DJ | 1 |
| Caballero-George, C; Digman, MA; Gratton, E; Planes, N; Vanderheyden, PPML | 1 |
| Chan, P; Chen, X; Cheng, Y; Li, Y; Liu, J; Liu, Z; Morrisey, E; Pi, J; Reilly, M; Shen, Y; Tomlinson, B; Wang, H; Yu, Z; Zhang, L; Zhang, Q; Zhang, Y; Zheng, X; Zhuang, T | 1 |
| Li, Y; Sun, L; Zhang, J | 1 |
| Alirezaei, A; Argani, H; Ghorbanihaghjo, A; Jabarpour, M; Panah, F; Ranjbarzadhag, M; Rashtchizadeh, N; Sanajou, D | 1 |
| Deng, F; Fang, S; Zhang, B; Zhang, Y | 1 |
| Gugerell, A; Gyöngyösi, M; Lukovic, D; Mester-Tonczar, J; Podesser, B; Spannbauer, A; Traxler, D; Winkler, J; Zlabinger, K | 1 |
| Chen, C; Huang, J; Huang, R; Liang, X; Liu, A; Ning, T; Nong, H; Qin, F; Tang, X | 1 |
| Feng, X; Guo, J; Liu, J; Lu, L; Tao, J; Xu, Z; Zhang, Y; Zhao, M; Zhu, D; Zhu, J | 1 |
| Bushinsky, DA; Buysse, JM; Wesson, DE | 1 |
| Gao, W; Liu, C; Lu, G; Man, S; Wang, Y; Xiang, H; Yang, L | 1 |
| Kang, W; Liu, C; Lu, H; Qiao, X; Yang, X; Zhang, S; Zhou, Z | 1 |
| Brazhkina, O; Chandrabhatla, AS; Holmes, JW; Nelson, AR; Saucerman, JJ; Zeigler, AC | 1 |
| Alves-Lopes, R; Camargo, LL; Montezano, AC; Neves, KB; Rios, FJ; Touyz, RM | 1 |
| Abbas, AM; Badi, RM; Bashir, SO; Mohammed, ME; Morsy, MD; Osman, OM; Saeed, AM | 1 |
| Aluko, EO; Fasanmade, AA; Nna, VU | 1 |
| Mosquera, J; Muñoz, N; Pedreañez, A | 1 |
| Chen, JW; Dai, B; Han, MX; Wang, ZZ; Zhang, GX; Zhang, H | 1 |
| Angelotti, ML; Corcoran, J; Fraser, D; Hendry, BM; Li, J; Noor, M; Papadimitriou, A; Piedagnel, R; Raby, K; Romagnani, P; Wilson, PD; Xu, Q | 1 |
| Aburel, OM; Angoulvant, D; Benoist, L; Chadet, S; Gabillard-Lefort, C; Ivanes, F; Muntean, DM; Piollet, M; Sturza, A | 1 |
| Eiken, O; Elia, A; Keramidas, ME; Kölegård, R; Sköldefors, H; Sundblad, P | 1 |
| Cho, SM; Jeon, YJ; Lee, DH; Rahmdel, M | 1 |
| Guo, K; Tang, Y; Yan, JH | 1 |
| Chen, G; Jiang, S; Lu, Y; Wang, D; Wang, X; Yang, Z; Zhu, L | 1 |
| Akita, K; Isobe, S; Isoda, K; Iwakura, Y; Minamino, T; Niida, T; Ohtomo, F; Sano, M; Sato-Okabayashi, Y; Shimada, K | 1 |
| Boshchenko, AA; Fu, F; Khaliulin, I; Logvinov, SV; Maslov, LN; Mukhomedzyanov, AV; Naryzhnaya, NV; Oeltgen, PR; Pei, JM; Popov, SV; Prasad, NR; Ryabov, VV; Voronkov, NS | 1 |
| Azizi, M; Babaahmadi-Rezaei, H; Beheshti-Nasab, H; Ghaderi-Zefrehi, H; Mehta, JL; Rezaei, M | 1 |
| Cheyne, L; Dawson, DK; Dhaun, N; Gamble, DT; Horgan, G; Khan, H; Mezincescu, AM; Newby, DE; Rudd, A | 1 |
| Kang, ZY; Li, DH; Liu, C; Liu, W; Xiao, Y; Yin, Z; Zhao, Y | 1 |
| Che, T; He, H; He, Y; Li, M; Li, Z; Lu, A; Shen, S; Zhou, W | 1 |
| Lyu, H; Xu, X; Xu, Y; Yu, B; Yu, X | 1 |
| Pao, AC; Raphael, KL; Ravikumar, NPG | 1 |
| Červenka, L; Gawrys, O; Jíchová, Š; Kala, P; Kompanowska-Jezierska, E; Maxová, H; Miklovič, M; Sadowski, J; Škaroupková, P; Táborský, M; Vaněčková, I; Vaňourková, Z; Veselka, J; Walkowska, A | 1 |
| Akiba, Y; Fukuda, K; Funahashi, A; Hashimoto, H; Katsuki, T; Kimura, M; Komuro, J; Kuoka, T; Kusumoto, D; Nakamura, T; Seki, T; Tokuoka, Y; Yamada, T; Yuasa, S | 1 |
| Catar, R; Hegner, B; Hilger, J; Kamhieh-Milz, J; Kleinau, G; Kretzschmar, T; Philippe, A; Riemekasten, G; Scheerer, P; Schindler, R; Zhao, H; Zhu, N | 1 |
70 review(s) available for angiotensin ii and endothelin-1
| Article | Year |
|---|---|
Hormonal regulation of cardiac cystic fibrosis transmembrane conductance regulator chloride channels.
Topics: Action Potentials; Adenylyl Cyclases; Angiotensin II; Animals; Autonomic Nervous System; Catecholamines; Chloride Channels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Endothelin-1; GTP-Binding Proteins; Heart; Myocardium; Phosphorylation; Signal Transduction | 1996 |
[The cardiac autocrine-paracrine system in the development of hypertrophy].
Topics: Angiotensin II; Animals; Cardiomegaly; Endothelin-1; Heart; Humans; Renin-Angiotensin System | 1997 |
[Molecular mechanism of cardiac hypertrophy and dysfunction].
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomyopathy, Hypertrophic; Endothelin-1; Heart Failure; Humans; Hypertension; Proto-Oncogene Proteins c-raf; Rats; Signal Transduction; Stress, Mechanical | 1997 |
Is there a rationale for combining angiotensin-converting enzyme inhibitors and calcium antagonists in cardiovascular disease?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Muscle, Smooth, Vascular; Myocardial Ischemia; Nitric Oxide | 1997 |
The renin-angiotensin system as a mediator of renal injury in hypertension.
Topics: Angiotensin II; Animals; Endothelin-1; Hemodynamics; Humans; Hypertension; Kidney; Nephrosclerosis; Renin-Angiotensin System | 1998 |
[HgCl2-induced acute renal failure and its pathophysiology].
Topics: Acute Kidney Injury; Angiotensin II; Animals; Disease Progression; Endothelin-1; Glomerular Filtration Rate; Humans; Kidney Tubular Necrosis, Acute; Mercuric Chloride; Vascular Resistance | 1998 |
Combination of ACE inhibitors and calcium antagonists: a logical approach.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Drug Therapy, Combination; Endothelin-1; Endothelium, Vascular; Humans; Muscle, Smooth, Vascular | 1998 |
[Mechanism involved in the onset of heart failure].
Topics: Angiotensin II; Animals; Calcium; Cardiomegaly; Endothelin-1; Heart Failure; Humans; Interleukin-1; Neurotransmitter Agents; Receptors, Adrenergic, beta; Ventricular Remodeling | 1998 |
[Interactions between the renin-angiotensin system, nitric oxide and endothelin].
Topics: Angiotensin II; Animals; Endothelin-1; Humans; Nitric Oxide; Renin; Renin-Angiotensin System; Vasoconstriction | 1998 |
The molecular mechanism of cardiac hypertrophy and failure.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Cardiomegaly; Endothelin-1; Hypertension; Myocardium; Renin-Angiotensin System; Signal Transduction; Sodium-Hydrogen Exchangers; Stress, Mechanical | 1999 |
[New concepts in the pathogenesis of essential hypertension].
Topics: Adult; Angiotensin II; Child; Diabetes Mellitus, Type 1; Endothelin-1; Humans; Hypertension; Nitric Oxide; Obesity; Poland; Risk Factors; Sodium, Dietary | 1999 |
Vasoactive substances in renal transplantation.
Topics: Adrenomedullin; Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Graft Survival; Humans; Kidney Transplantation; Nitric Oxide; Peptides; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Plasma endothelin levels: a meaningless number?
Topics: Adaptation, Physiological; Angioplasty; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cold Temperature; Endothelin-1; Humans; Hypertension; Hypoxia; Kidney; Renal Artery Obstruction; Renin-Angiotensin System; Sympathetic Nervous System | 2000 |
Endothelin: role in experimental hypertension.
Topics: Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Fructose; Hypertension; Insulin Resistance; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Dahl; Rats, Inbred SHR | 2000 |
Recent advances in the management of chronic heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Cytokines; Disease Progression; Endothelin-1; Heart Failure; Humans | 2000 |
Endothelial dysfunction in hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine; Clinical Trials as Topic; Endothelin-1; Endothelins; Endothelium, Vascular; Free Radicals; Humans; Hypertension; Nitric Oxide; Rats; Rats, Inbred SHR; Research; Risk Factors; Vasodilation | 2000 |
Endothelin, renal diseases, and hypertension.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Endothelin-1; Endothelins; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Nitric Oxide | 2000 |
The anatomy, physiology and molecular pathways of vascular erectile dysfunction.
Topics: Angiotensin II; Calcium Channels; Endothelin-1; Humans; Impotence, Vasculogenic; Male; Muscle, Smooth, Vascular; Nitric Oxide; Potassium Channels | 2000 |
Role of transforming growth factor-beta1 in the progression of chronic allograft nephropathy.
Topics: Angiotensin II; Antihypertensive Agents; Biomarkers; Disease Progression; Endothelin-1; Humans; Kidney Transplantation; Losartan; Renin-Angiotensin System; Transforming Growth Factor beta; Transplantation, Homologous | 2001 |
[Cardiovascular abnormalities as a cause of hypertension].
Topics: Adrenomedullin; Angiotensin II; Animals; Cardiovascular System; Catecholamines; Cell Division; Endothelin-1; Humans; Hypertension; Insulin; Kallikrein-Kinin System; Muscle, Smooth, Vascular; Natriuretic Agents; Nitric Oxide; Peptides; Vasoconstriction | 2001 |
The regulation of sympathetic outflow in heart failure. The roles of angiotensin II, nitric oxide, and exercise training.
Topics: Angiotensin II; Animals; Cardiac Output, Low; Chronic Disease; Endothelin-1; Nitric Oxide; Physical Conditioning, Animal; Sympathetic Nervous System | 2001 |
Regulation of apoptosis by vasoactive peptides.
Topics: Adrenomedullin; Angiotensin II; Animals; Apoptosis; Atrial Natriuretic Factor; Endothelin-1; Humans; Lung; Lung Diseases; Peptides; Vasoactive Intestinal Peptide | 2001 |
Genetic determinants of vascular reactivity.
Topics: Angiotensin II; Blood Pressure; Blood Vessels; Cardiovascular Diseases; Endothelin-1; Endothelins; Genotype; Humans; Hypertension; Nitric Oxide Synthase; Polymorphism, Genetic; Protein Precursors; Renin-Angiotensin System | 2002 |
Molecular and cellular mechanisms of mechanical stress-induced cardiac hypertrophy.
Topics: Angiotensin II; Calcineurin; Calcium; Cardiomegaly; Endothelin-1; Hemodynamics; Humans; Protein Kinases; Signal Transduction; Stress, Mechanical | 2002 |
Stretch-activated pathways and left ventricular remodeling.
Topics: Angiotensin II; Animals; Endothelin-1; GTP-Binding Proteins; Heart Failure; Humans; Insulin-Like Growth Factor I; Integrins; Interleukin-6; Myocardial Contraction; Myocytes, Cardiac; Signal Transduction; Ventricular Remodeling | 2002 |
Signaling pathways activated by vasoactive peptides in the cardiac myocyte and their role in myocardial pathologies.
Topics: Angiotensin II; Animals; Bradykinin; Endothelin-1; Humans; Hypertrophy, Left Ventricular; Myocytes, Cardiac; Protein Kinase C; Renin-Angiotensin System; Signal Transduction | 2002 |
Novel mechanisms of sympatho-excitation in chronic heart failure.
Topics: Angiotensin II; Baroreflex; Endothelin-1; Excitatory Postsynaptic Potentials; Heart Failure; Humans; Nitric Oxide; Sympathetic Nervous System | 2002 |
[Vasoactive peptides and the development of renal sclerosis: contribution of transgenes].
Topics: Angiotensin II; Animals; Collagen Type II; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Fibrosis; Genes, Reporter; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Luciferases; MAP Kinase Signaling System; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Renin-Angiotensin System; Sclerosis; Transforming Growth Factor beta; Transgenes | 2002 |
Inhibition of the tonic contraction in the treatment of erectile dysfunction.
Topics: Adrenergic Agonists; Adult; Aged; Aging; Amides; Angiotensin II; Calcium Signaling; Cyclic AMP; Endothelin-1; Erectile Dysfunction; Forecasting; Humans; Intracellular Signaling Peptides and Proteins; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Penis; Protein Serine-Threonine Kinases; Pyridines; rho-Associated Kinases; rhoA GTP-Binding Protein; Vasoactive Intestinal Peptide | 2003 |
Obesity-associated activation of angiotensin and endothelin in the cardiovascular system.
Topics: Adipocytes; Adiponectin; Angiotensin II; Animals; Endothelin-1; Endothelium, Vascular; Hormones, Ectopic; Humans; Hypertension; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Kidney; Leptin; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Renin-Angiotensin System; Resistin | 2003 |
Angiotensin II and endothelin induce inflammation and thereby promote hypertension-induced end-organ damage.
Topics: Angiotensin II; Animals; Endothelin-1; Gene Expression Regulation; Humans; Hypertension; NF-kappa B; Vasculitis | 2003 |
The role of the endothelium in the control of vascular function.
Topics: Angiotensin II; Arteriosclerosis; Cardiovascular Diseases; Cell Adhesion Molecules; Coagulants; Diabetes Mellitus; Endothelin-1; Endothelium, Vascular; Female; Humans; Pre-Eclampsia; Pregnancy; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
[Adsorption characteristics of the synthetic polymer dialysis membranes].
Topics: Acrylic Resins; Angiotensin II; Cellulose; Dialysis; Endothelin-1; Humans; Membranes, Artificial; Norepinephrine; Polymers; Polymethyl Methacrylate; Sulfones; Time Factors | 2004 |
Targets for vascular protection after acute ischemic stroke.
Topics: Acute Disease; Angiopoietins; Angiotensin II; Antioxidants; Apoptosis; Blood-Brain Barrier; Brain Edema; Brain Ischemia; Cerebral Arteries; Cerebral Hemorrhage; Chronic Disease; Endothelin-1; Endothelium, Vascular; Humans; Inflammation Mediators; Matrix Metalloproteinases; Neuroprotective Agents; Neutrophils; Oxidative Stress; Reactive Oxygen Species; Vascular Endothelial Growth Factor A; Vasculitis | 2004 |
[Effect of adrenomedullin on cardiac myocytes and fibroblasts].
Topics: Adrenomedullin; Angiotensin II; Animals; Apoptosis; Calcium; Cardiomegaly; Cell Division; Cyclic AMP; Endothelin-1; Heart Failure; Humans; Myoblasts, Cardiac; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Peptides; Protein Kinase C; Signal Transduction; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2004 |
[Mitogenic action of endothelin on fibroblasts].
Topics: Angiotensin II; Animals; Cell Division; Collagen; Endothelin-1; Extracellular Matrix; Fibroblast Growth Factor 2; Fibroblasts; Glomerulosclerosis, Focal Segmental; Humans; Hypertension; Liver Cirrhosis; Myoblasts, Cardiac; Myocardial Infarction; Pulmonary Fibrosis; Receptors, Endothelin; Transforming Growth Factor beta; Ventricular Remodeling | 2004 |
[Role of endothelin in the development of cardiac hypertrophy].
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Communication; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Hemodynamics; Humans; Receptor, Endothelin A; Stress, Mechanical; Ventricular Remodeling | 2004 |
Endothelin, angiotensin, and oxidative stress in hypertension.
Topics: Angiotensin II; Animals; Blood Vessels; Endothelin-1; Humans; Hypertension; Oxidative Stress; Receptor, Endothelin B | 2005 |
Blood flow: a key regulatory component of corpus luteum function in the cow.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Cattle; Corpus Luteum; Dinoprost; Endothelin-1; Female; Gene Expression; Luteolysis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; RNA, Messenger | 2005 |
Angiotensin II and vascular inflammation.
Topics: Angiotensin II; Animals; Blood Vessels; Capillary Permeability; Cyclooxygenase 2; Endothelin-1; Humans; Inflammation; Membrane Proteins; Nitric Oxide; Prostaglandin-Endoperoxide Synthases; Signal Transduction | 2005 |
Disruptions and detours in the myocardial matrix highway and heart failure.
Topics: Angiotensin II; Disease Progression; Endothelin-1; Extracellular Matrix; Heart Failure; Humans; Hypertrophy, Left Ventricular; Integrins; Matrix Metalloproteinases; Myocardial Infarction; Myocardium; Transforming Growth Factor beta; Ventricular Remodeling | 2005 |
[Effects of sex steroid hormones on renal functions in molecular biology].
Topics: Angiotensin II; Animals; Endothelin-1; Estrogens; Female; Free Radicals; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Male; Plasminogen Activator Inhibitor 1; Receptors, Estrogen; Renin-Angiotensin System; Sex Characteristics; Vascular Endothelial Growth Factor A | 2006 |
[Endothelin-1, angiotensin II and cancer].
Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antineoplastic Agents; Benzimidazoles; Biphenyl Compounds; Clinical Trials as Topic; Endothelin-1; Humans; Neoplasm Invasiveness; Neoplasms; Neovascularization, Pathologic; Receptors, Angiotensin; Receptors, Endothelin; Tetrazoles | 2006 |
The interrelation of the angiotensin and endothelin systems on the modulation of NAD(P)H oxidase.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Endothelin-1; Humans; NADPH Oxidases | 2006 |
Diabetic nephropathy: from mechanisms to rational therapies.
Topics: Angiotensin II; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelin-1; Glycation End Products, Advanced; Humans; Hypertension; Protein Kinase C; Urotensins | 2006 |
Physical (in)activity and endothelium-derived constricting factors: overlooked adaptations.
Topics: Angiotensin II; Animals; Endothelin-1; Endothelium, Vascular; Humans; Motor Activity; Thromboxane A2; Vasoconstriction | 2008 |
Fat intake and cardiovascular response.
Topics: Angiotensin II; Animals; Cardiovascular Diseases; Cardiovascular System; Dietary Fats; Endothelin-1; Humans; Nitric Oxide; Obesity; Reactive Oxygen Species; Renin-Angiotensin System; Risk Factors | 2008 |
Acute neurohumoral modulation of diastolic function.
Topics: Angiotensin II; Animals; Diastole; Endothelin-1; Ghrelin; Heart Failure, Diastolic; Humans; Myocardial Contraction; Neurotransmitter Agents; Nitric Oxide; Urotensins | 2009 |
Local regulation of corpus luteum development and regression in the cow: Impact of angiogenic and vasoactive factors.
Topics: Angiopoietin-1; Angiopoietin-2; Angiotensin II; Animals; Cattle; Corpus Luteum; Dinoprost; Endothelin-1; Female; Fibroblast Growth Factor 2; Luteolysis; Nitric Oxide; Vascular Endothelial Growth Factor A | 2009 |
Mechanisms underlying the vascular actions of endothelin 1, angiotensin II and bradykinin in the rat carotid.
Topics: Angiotensin II; Animals; Bradykinin; Carotid Arteries; Endothelin-1; Endothelium, Vascular; Rats; Receptor, Endothelin A; Receptors, Angiotensin; Receptors, Bradykinin; Signal Transduction | 2009 |
Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure.
Topics: Angiotensin II; Animals; Antidiuretic Agents; Antihypertensive Agents; Benzazepines; Biomarkers; Bosentan; Catecholamines; Drug Therapy, Combination; Endothelin-1; Heart Failure; Humans; Peptides, Cyclic; Renin-Angiotensin System; Sulfonamides; Sympathetic Nervous System; Tolvaptan; Treatment Outcome; Vasopressins | 2010 |
Endothelial dysfunction: a strategic target in the treatment of hypertension?
Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Dinucleoside Phosphates; Endothelin-1; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Humans; Hypertension; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Thromboxane; Vasoconstrictor Agents | 2010 |
Potential therapeutic targets for cardiac fibrosis: TGFbeta, angiotensin, endothelin, CCN2, and PDGF, partners in fibroblast activation.
Topics: Angiotensin II; Animals; Cardiovascular Agents; Connective Tissue Growth Factor; Drug Design; Endothelin-1; Extracellular Matrix Proteins; Fibroblasts; Fibrosis; Heart Diseases; Humans; Myocardium; Platelet-Derived Growth Factor; Signal Transduction; Transforming Growth Factor beta | 2010 |
Endothelial dysfunction in adults with obstructive sleep apnea.
Topics: Adult; Angiotensin II; Apoptosis; Biomarkers; Blood Coagulation Disorders; Cardiovascular Diseases; Continuous Positive Airway Pressure; Endothelin-1; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress; Risk Factors; Sleep Apnea, Obstructive | 2011 |
Vascular and immune regulation of corpus luteum development, maintenance, and regression in the cow.
Topics: Angiogenic Proteins; Angiotensin II; Animals; Cattle; Corpus Luteum; Endothelin-1; Eosinophils; Female; Immune System; Luteolysis; Macrophages; Neovascularization, Physiologic; Neutrophils; Nitric Oxide; Pregnancy; Vascular Endothelial Growth Factor A | 2012 |
Vascular actions of aldosterone.
Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Vessels; Cardiovascular Diseases; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypertrophy; Metabolic Syndrome; Mineralocorticoid Receptor Antagonists; Mineralocorticoids; Muscle, Smooth, Vascular; Oxidative Stress; Receptor, Endothelin A; Receptors, Mineralocorticoid; Renin-Angiotensin System; Signal Transduction; Sodium; Vasculitis; Vasoconstriction | 2013 |
Neurovascular interactions in the retina: physiological and pathological roles.
Topics: Angiotensin II; Catecholamines; Cell Communication; Diabetic Retinopathy; Disease Progression; Drug Discovery; Endothelin Receptor Antagonists; Endothelin-1; Glaucoma; Homeostasis; Molecular Targeted Therapy; N-Methylaspartate; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Synthase Type II; Potassium Channels, Calcium-Activated; Receptors, GABA; Retina; Retinal Diseases; Retinal Vessels | 2013 |
Myofibroblasts: trust your heart and let fate decide.
Topics: Actins; Angiotensin II; Cell Differentiation; Endothelin-1; Extracellular Matrix; Fibrosis; Gene Expression Regulation; Heart; Humans; Mechanotransduction, Cellular; Mitogen-Activated Protein Kinases; Myofibroblasts; Serum Response Factor; Transforming Growth Factor beta | 2014 |
Proinflammation: the key to arterial aging.
Topics: Aged; Aging; Angiotensin II; Animals; Antigens, Surface; Arteries; Arteritis; Atherosclerosis; Calpain; Chemokine CCL2; Endothelin-1; Humans; Hypertension; Inflammation; Inflammation Mediators; Matrix Metalloproteinase 2; Middle Aged; Milk Proteins; Muscle, Smooth, Vascular; Nitric Oxide; Reactive Oxygen Species; Receptors, CCR2; Transforming Growth Factor beta1 | 2014 |
Ca2+/calmodulin-dependent protein kinase- II in vasoactive peptide- induced responses and vascular biology.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Movement; Cell Proliferation; Endothelin-1; Gene Expression Regulation; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction | 2014 |
Recent insights in the paracrine modulation of cardiomyocyte contractility by cardiac endothelial cells.
Topics: Angiotensin II; Animals; Endothelin-1; Humans; Myocardial Contraction; Myocytes, Cardiac; Neuregulin-1; Nitric Oxide; Nitric Oxide Synthase Type III; Paracrine Communication | 2014 |
Getting to the heart of the matter: new insights into cardiac fibrosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Atrophy; Cicatrix; Connective Tissue Growth Factor; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypoxia; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; Myofibroblasts; Platelet-Derived Growth Factor; Pyridones; Rats; Signal Transduction; Transforming Growth Factor beta | 2015 |
Regulation of Giα protein expression by vasoactive peptides in hypertension: molecular mechanisms.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Endothelin-1; Gene Expression Regulation; GTP-Binding Protein alpha Subunits; Humans; Hypertension; Models, Cardiovascular; Models, Immunological; Signal Transduction; Vasomotor System | 2014 |
[Vascular factors in glaucoma].
Topics: Angiotensin II; Arterial Pressure; Blood Viscosity; Endothelin-1; Endothelium, Vascular; Eye; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Nitric Oxide; Prostaglandins I; Vascular Resistance; Vasoconstriction; Vasodilation; Vasomotor System | 2015 |
Vascular Fibrosis in Aging and Hypertension: Molecular Mechanisms and Clinical Implications.
Topics: Aging; Angiotensin II; Endothelin-1; Endothelium, Vascular; Fibrosis; Humans; Hypertension; Matrix Metalloproteinases; Risk Factors; Smad Proteins; Transforming Growth Factor beta1; Vascular Stiffness | 2016 |
The impact of dyslipidemia and oxidative stress on vasoactive mediators in patients with renal dysfunction.
Topics: Angiotensin II; Dyslipidemias; Endothelin-1; Humans; Nitric Oxide; Oxidative Stress; Proprotein Convertase 9; Renal Insufficiency, Chronic | 2019 |
Computational model predicts paracrine and intracellular drivers of fibroblast phenotype after myocardial infarction.
Topics: Angiotensin II; Animals; Cell Differentiation; Collagen; Computer Simulation; Endothelin-1; Extracellular Matrix; Fibroblasts; Gene Expression Regulation; Humans; Interleukin-1; Models, Biological; Myocardial Infarction; NF-kappa B; Paracrine Communication; Phenotype; Rats; Signal Transduction; Smad Proteins; Transforming Growth Factor beta; Wound Healing | 2020 |
Oxidative Stress: A Unifying Paradigm in Hypertension.
Topics: Aldosterone; Angiotensin II; Endothelin-1; Endothelium, Vascular; Humans; Hypertension; Inflammation; Intercellular Signaling Peptides and Proteins; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sex Factors; Signal Transduction; Vascular Remodeling; Vascular Stiffness; Vasoconstriction | 2020 |
Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms.
Topics: Adrenergic Agents; Angiotensin II; Endothelin-1; Humans; Inflammasomes; Ischemia; Myocytes, Cardiac; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Reperfusion; Reperfusion Injury | 2022 |
Acid-Mediated Kidney Injury Across the Spectrum of Metabolic Acidosis.
Topics: Acidosis; Aldosterone; Ammonium Compounds; Angiotensin II; Citrates; Endothelin-1; Humans; Kidney; Renal Insufficiency, Chronic | 2022 |
35 trial(s) available for angiotensin ii and endothelin-1
| Article | Year |
|---|---|
Captopril does not acutely modulate plasma endothelin-1 concentration in human congestive heart failure.
Topics: Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Radioimmunoassay; Renin; Stroke Volume | 1996 |
Effects of angiotensin-II infusion at pressor and subpressor doses on endothelin-1 plasma levels in healthy men.
Topics: Adult; Angiotensin II; Endothelin-1; Humans; Hypertension; Male; Reference Values | 1997 |
Investigations on the renin-angiotensin system in acute severe asthma.
Topics: Acute Disease; Adolescent; Adult; Angiotensin II; Asthma; Catecholamines; Endothelin-1; Female; Forced Expiratory Volume; Heart Rate; Humans; Male; Middle Aged; Oxygen Consumption; Peak Expiratory Flow Rate; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Sensitivity and Specificity; Severity of Illness Index | 1997 |
The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators.
Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Bosentan; Creatinine; Double-Blind Method; Endothelin Receptor Antagonists; Endothelin-1; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sulfonamides | 1998 |
Effect of angiotensin infusion on plasma endothelin in pregnancy.
Topics: Adult; Angiotensin II; Endothelin-1; Female; Humans; Infusions, Intravenous; Pregnancy; Vasoconstrictor Agents | 1998 |
Inhibition of neutral endopeptidase causes vasoconstriction of human resistance vessels in vivo.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Blood Pressure; Coronary Vessels; Cross-Over Studies; Cyclohexanecarboxylic Acids; Enalapril; Endothelin-1; Humans; Hypertension; Injections, Intra-Arterial; Male; Middle Aged; Myocardium; Neprilysin; Peptides, Cyclic; Protease Inhibitors; Renin; Single-Blind Method; Thiorphan; Vasoconstriction | 1998 |
Influence of angiotensin-converting enzyme inhibitor enalaprilat on endothelial-derived substances in the critically ill.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cell Adhesion Molecules; Critical Illness; Double-Blind Method; Enalaprilat; Endothelin-1; Endothelium, Vascular; Female; Hemodynamics; Humans; Inflammation; Male; Middle Aged; Prospective Studies; Sepsis; Survival Analysis; Thrombomodulin | 1998 |
Regulation of peripheral vascular tone in patients with heart failure: contribution of angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Endothelin-1; Female; Forearm; Heart Failure; Humans; Infusions, Intra-Arterial; Losartan; Lower Body Negative Pressure; Male; Middle Aged; Norepinephrine; Plethysmography; Regional Blood Flow; Vascular Resistance; Vasoconstrictor Agents | 1998 |
Effect of infused angiotensin II on the bronchoconstrictor activity of inhaled endothelin-1 in asthma.
Topics: Adult; Angiotensin II; Asthma; Blood Pressure; Bronchial Hyperreactivity; Bronchoconstriction; Double-Blind Method; Drug Synergism; Endothelin-1; Female; Humans; Male; Middle Aged | 1999 |
Alterations in angiotensin II release and vascular reactivity in hypertensive men: a pilot study.
Topics: Adult; Angiotensin II; Blood Glucose; Cold Temperature; Endothelin-1; Endothelium, Vascular; Femoral Artery; Glucose Clamp Technique; Humans; Hyperinsulinism; Hypertension; Indocyanine Green; Insulin; Male; Norepinephrine; Pilot Projects; Vascular Resistance; Vasoconstrictor Agents | 1999 |
Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Double-Blind Method; Endothelin-1; Exercise Tolerance; Female; Heart Failure; Humans; Lisinopril; Male; Middle Aged; Neprilysin; Norepinephrine; Prospective Studies; Pyridines; Radionuclide Ventriculography; Severity of Illness Index; Survival Rate; Thiazepines; Treatment Outcome | 2000 |
The effects of verapamil SR and bisoprolol on reducing the sympathetic nervous system's activity.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Endothelin-1; Epinephrine; Female; Hand Strength; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sympathetic Nervous System; Sympatholytics; Verapamil | 2000 |
Effect of losartan on angiotensin II-mediated endothelin and prostanoid excretion in humans.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Endothelin-1; Humans; Losartan; Male; Middle Aged; Placebos; Prostaglandins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin | 2000 |
Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Endothelin-1; Female; Hemodynamics; Humans; Kidney; Kidney Transplantation; Losartan; Male; Middle Aged; Renal Circulation; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
[Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension].
Topics: Aged; Angiotensin II; Drugs, Chinese Herbal; Endothelin-1; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Vasodilator Agents | 2000 |
Changes in renal and systemic hemodynamics after NO-synthase inhibition in males with family history of hypertension.
Topics: Adult; Angiotensin II; Blood Pressure; Double-Blind Method; Endothelin-1; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Medical Records; Natriuresis; Nitric Oxide Synthase; omega-N-Methylarginine; Renal Circulation; Renin | 2002 |
Endothelin ETA receptor-subtype specific antagonism does not mitigate the acute systemic or renal effects of exogenous angiotensin II in humans.
Topics: Adult; Angiotensin II; Cross-Over Studies; Double-Blind Method; Endothelin Receptor Antagonists; Endothelin-1; Glomerular Filtration Rate; Hemodynamics; Humans; Inulin; Male; p-Aminohippuric Acid; Peptides, Cyclic; Renal Circulation; Renal Plasma Flow; Vascular Resistance | 2002 |
Beneficial neurohormonal profile of spironolactone in severe congestive heart failure: results from the RALES neurohormonal substudy.
Topics: Aged; Aged, 80 and over; Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Natriuretic Peptide, Brain; Spironolactone; Treatment Outcome | 2002 |
Effect of four oral contraceptives on thyroid hormones, adrenal and blood pressure parameters.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Contraceptives, Oral, Combined; Double-Blind Method; Drug Administration Schedule; Endothelin-1; Estradiol; Ethinyl Estradiol; Female; Humans; Hydrocortisone; Levonorgestrel; Nandrolone; Thyroid Hormones; Treatment Outcome | 2003 |
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin II; Blood Chemical Analysis; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Endothelin-1; Female; Flavonoids; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Nitric Oxide; Pinus; Plant Extracts; Platelet Aggregation Inhibitors; Treatment Outcome | 2004 |
Combined inhibition of angiotensin II and endothelin suppresses the brain natriuretic peptide response to developing heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bosentan; Cardiac Output; Cardiac Output, Low; Cardiac Pacing, Artificial; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Female; Infusions, Parenteral; Losartan; Natriuretic Peptide, Brain; Renin; Sheep; Sulfonamides | 2004 |
Endocrinologic response to vasopressin infusion in advanced vasodilatory shock.
Topics: Adrenocorticotropic Hormone; Aged; Aldosterone; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Endocrine Glands; Endothelin-1; Female; Hemodynamics; Humans; Hydrocortisone; Infusions, Intravenous; Male; Norepinephrine; Prolactin; Prospective Studies; Renin; Shock | 2004 |
[Clinical study on effect of luohuo capsule in treating essential hypertension of phlegm-stasis blocking collateral type].
Topics: Aged; Angiotensin II; Antihypertensive Agents; Blood Viscosity; Capsules; Diagnosis, Differential; Drugs, Chinese Herbal; Endothelin-1; Female; Hemorheology; Humans; Hypertension; Male; Medicine, Chinese Traditional; Middle Aged; Nitric Oxide; Phytotherapy | 2004 |
Carvedilol therapy is associated with a sustained decline in brain natriuretic peptide levels in patients with congestive heart failure.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Carbazoles; Carvedilol; Endothelin-1; Endothelins; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Propanolamines | 2005 |
ETa-receptor blockade, but not ACE inhibition, blunts retinal vessel response during isometric exercise.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cross-Over Studies; Double-Blind Method; Enalapril; Endothelin A Receptor Antagonists; Endothelin-1; Exercise Test; Female; Humans; Isometric Contraction; Male; Peptides, Cyclic; Physical Exertion; Placebo Effect; Receptor, Endothelin A; Retinal Vessels; Vasoconstriction | 2006 |
The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: influence of the G-protein beta3 subunit (GNB3) C825T polymorphism.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin-1; Genotype; Heterotrimeric GTP-Binding Proteins; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Norepinephrine; Polymorphism, Genetic; Regional Blood Flow; Skin; Tetrazoles; Valine; Valsartan; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Secondary pulmonary hypertension: haemodynamic effects of torasemide versus furosemide.
Topics: Administration, Oral; Aged; Angiotensin II; Antihypertensive Agents; Cardiac Output; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Endothelin-1; Female; Furosemide; Hemodynamics; Humans; Hypertension, Pulmonary; Injections, Intravenous; Lung; Male; Middle Aged; Pilot Projects; Prospective Studies; Stroke Volume; Sulfonamides; Torsemide; Treatment Outcome | 2008 |
Relationships between plasma levels of matrix metalloproteinases and neurohormonal profile in patients with heart failure.
Topics: Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Endothelin-1; Extracellular Matrix; Female; Heart Failure; Humans; Male; Matrix Metalloproteinases; Middle Aged; Neurotransmitter Agents; Tissue Inhibitor of Metalloproteinases | 2008 |
The effects of strength training on central arterial compliance in middle-aged and older adults.
Topics: Age Factors; Aging; Angiotensin II; Blood Pressure; Body Mass Index; Carotid Arteries; Cold Temperature; Compliance; Endothelin-1; Exercise; Female; Humans; Male; Manometry; Middle Aged; Muscle Strength; Muscle, Skeletal; Oxygen Consumption; Time Factors; Ultrasonography; Vasodilation | 2008 |
Combined vs. Isoflurane/Fentanyl anesthesia for major abdominal surgery: Effects on hormones and hemodynamics.
Topics: Abdomen; Adult; Aged; Anesthesia, Epidural; Anesthesia, General; Angiotensin II; Blood Glucose; Blood Pressure; Drug Therapy, Combination; Endothelin-1; Epinephrine; Female; Fentanyl; Heart Rate; Hemodynamics; Humans; Hydrocortisone; Isoflurane; Male; Middle Aged; Osmolar Concentration; Plasma; Prospective Studies; Sodium; Vasoconstrictor Agents | 2008 |
Effects of enalapril, candesartan or both on neurohumoral activation and LV volumes and function in patients with heart failure not treated with a beta-blocker.
Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Peptide Fragments; Radionuclide Angiography; Stroke Volume; Tetrazoles; Treatment Outcome; Ventricular Function, Left | 2009 |
Hypertension induced by the tyrosine kinase inhibitor sunitinib is associated with increased circulating endothelin-1 levels.
Topics: Aged; Angiotensin II; Animals; Blood Pressure; Bradykinin; Carcinoma, Renal Cell; Cells, Cultured; Coronary Circulation; Endothelial Cells; Endothelin-1; Female; Gastrointestinal Stromal Tumors; Heart; Heart Rate; Humans; Hypertension; In Vitro Techniques; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Rats; Rats, Inbred WKY; Receptor Protein-Tyrosine Kinases; Renin; Sunitinib; Vascular Endothelial Growth Factor A | 2010 |
Vascular and pharmacokinetic effects of EndoTAG-1 in patients with advanced cancer and liver metastasis.
Topics: Adult; Aged; Angiogenesis Inhibitors; Angiotensin II; Area Under Curve; Breast Neoplasms; Colorectal Neoplasms; Contrast Media; Endothelin-1; Female; Humans; Interleukins; Liposomes; Liver Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Paclitaxel; Pancreatic Neoplasms; Ultrasonography; Vascular Endothelial Growth Factor A | 2012 |
Inappropriately elevated endothelin-1 plays a role in the pathogenesis of intradialytic hypertension.
Topics: Adrenomedullin; Adult; Aged; Aldosterone; Angiotensin II; Endothelin-1; Female; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Nitric Oxide; Norepinephrine; Peptidyl-Dipeptidase A; Renal Dialysis | 2015 |
Analysis of the Clinical Effect of Implementing Health Education in the Process of Ministration Elderly Hypertensive Sufferers.
Topics: Aged; Angiotensin II; Anxiety; Depression; Endothelin-1; Health Education; Humans; Quality of Life; Superoxide Dismutase | 2022 |
622 other study(ies) available for angiotensin ii and endothelin-1
| Article | Year |
|---|---|
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
Effects of the neutral endopeptidase inhibitor, SQ 28,603, on regional haemodynamic responses to atrial natriuretic peptide or proendothelin-1 [1-38] in conscious rats.
Topics: Alanine; Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Endothelin-1; Endothelins; Heart Rate; Injections, Intravenous; Male; Neprilysin; Protein Precursors; Rats | 1992 |
Induction of endothelin-1 gene by angiotensin and vasopressin in endothelial cells.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Arginine Vasopressin; Base Sequence; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression; Molecular Sequence Data; Protein Precursors; RNA, Messenger; Tissue Distribution; Vasopressins | 1992 |
Phosphoramidon inhibits the conversion of big ET-1 into ET-1 in the pithed rat and in isolated perfused rat kidneys.
Topics: Angiotensin I; Angiotensin II; Animals; Aspartic Acid Endopeptidases; Blood Pressure; Decerebrate State; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Glycopeptides; Hemodynamics; In Vitro Techniques; Kidney; Male; Metalloendopeptidases; Norepinephrine; Protein Precursors; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1993 |
Regulation of endothelin-1 mRNA by angiotensin II in rat heart endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blotting, Northern; Cells, Cultured; Endothelin-1; Endothelins; Endothelium, Vascular; Gene Expression Regulation; Imidazoles; Losartan; Myocardium; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Protein Precursors; Protein Synthesis Inhibitors; Rats; RNA, Messenger; Tetrazoles | 1993 |
Effect of an AT1 receptor antagonist (CV-11974) on angiotensin II-induced cardiomyocyte hypertrophy in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cardiomegaly; Cells, Cultured; DNA, Complementary; Endothelin-1; Endothelins; Heart; Imidazoles; Muscle, Smooth, Vascular; Myocardium; Protein Precursors; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Tetrazoles | 1994 |
Regulation of endothelin-1 biosynthesis.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Platelets; Bradykinin; Cell Hypoxia; Endothelin-1; Endothelins; Gene Expression Regulation; Humans; Insulin; Protein Biosynthesis; Protein Precursors; Protein Processing, Post-Translational; RNA, Messenger; Stress, Mechanical; Thrombin; Transcription, Genetic; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vasopressins | 1994 |
Role of calcium-dependent K+ channels in the regulation of arterial and venous tone by nitric oxide in pigs.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Blood Vessels; Blood Volume; Calcium; Cardiac Output; Charybdotoxin; Endothelin-1; Enzyme Inhibitors; Male; Nitric Oxide; Norepinephrine; Penicillamine; Potassium Channels; S-Nitroso-N-Acetylpenicillamine; Swine; Vascular Resistance; Vasodilator Agents | 1996 |
Modulation of Ca2+ transients in neonatal and adult rat cardiomyocytes by angiotensin II and endothelin-1.
Topics: Age Factors; Angiotensin II; Animals; Calcium; Cells, Cultured; Endothelin-1; Fluorescent Dyes; Fura-2; Myocardium; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1996 |
Natriuretic effect of non-pressor doses of endothelin-1 in conscious dogs.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Endothelin-1; Female; Heart Rate; Kidney; Urination | 1996 |
Evidence that both ETA and ETB receptor subtypes are involved in the in vivo aldosterone secretagogue effect of endothelin-1 in rats.
Topics: Adrenal Cortex; Aldosterone; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Male; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 1996 |
Renal effects of acute and chronic nitric oxide inhibition in experimental diabetes.
Topics: Angiotensin II; Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Time Factors | 1996 |
Intracellular Ca2+ modulation by angiotensin II and endothelin-1 in cardiomyocytes and fibroblasts from hypertrophied hearts of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Calcium; Endothelin-1; Fibroblasts; Heart; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Species Specificity; Tetrazoles; Vasoconstrictor Agents; Viper Venoms | 1996 |
Effect of an endothelin antagonist on hemodynamic responses to angiotensin II.
Topics: Angiotensin II; Animals; Bosentan; Endothelin-1; Hemodynamics; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Sulfonamides | 1996 |
Angiotensin II, via an action at AT1 receptors, may modulate the behavioural effects of ET-1 in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Biphenyl Compounds; Drug Synergism; Endothelin-1; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
Endothelin-1 regulates normal cardiovascular development and cardiac cellular hypertrophy.
Topics: Amino Acids; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cardiovascular System; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Expression; Hypertrophy; Mice; Mice, Knockout; Myocardium; Peptides, Cyclic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Stress, Mechanical | 1996 |
Effects of endothelin-1 on [Ca2+]i-shortening trajectory and Ca2+ sensitivity in rabbit single ventricular cardiomyocytes loaded with indo-1/AM: comparison with the effects of phenylephrine and angiotensin II.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Chelating Agents; Endothelin-1; Humans; Hydrolysis; Indoles; Infant; Male; Myocardial Contraction; Myocardium; Phenylephrine; Phosphatidylinositols; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta | 1996 |
Studies on endothelin receptors in the zonae fasciculata/reticularis of the rat adrenal cortex: contrast with the zona glomerulosa.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Endothelin Receptor Antagonists; Endothelin-1; Female; Male; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Zona Fasciculata; Zona Glomerulosa; Zona Reticularis | 1996 |
Protein kinase C, but not tyrosine kinases or Ras, plays a critical role in angiotensin II-induced activation of Raf-1 kinase and extracellular signal-regulated protein kinases in cardiac myocytes.
Topics: Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Genistein; Insulin; Isoflavones; Mitogen-Activated Protein Kinase 1; Myocardium; Polyenes; Polyunsaturated Alkamides; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; ras Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Acute effect of endothelin-1 on lung oedema induced by alpha-naphthylthiourea (ANTU).
Topics: Angiotensin II; Animals; Aspartic Acid Endopeptidases; Body Weight; Bosentan; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Male; Metalloendopeptidases; Organ Size; Pleural Effusion; Protease Inhibitors; Pulmonary Edema; Rats; Sulfonamides; Thiourea | 1996 |
Combined inhibition of endothelin and angiotensin II receptors blocks volume load-induced cardiac hormone release.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Function, Right; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Volume; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hemodynamics; Hormones; Imidazoles; Losartan; Male; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Peptides, Cyclic; Plasma Substitutes; Pressure; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 1997 |
Cardiac angiotensin converting enzyme and endothelin receptor in rats with chronic myocardial infarction.
Topics: Angiotensin II; Animals; Autoradiography; Cardiomegaly; Chronic Disease; Endothelin-1; Female; Heart Failure; Image Processing, Computer-Assisted; Iodine Radioisotopes; Ligation; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Endothelin; Renin; Ventricular Function, Left | 1996 |
Endothelin and angiotensin II stimulation of Na+-H+ exchange is impaired in cardiac hypertrophy.
Topics: Amiloride; Ammonium Chloride; Angiotensin II; Animals; Body Weight; Calcium; Cardiomegaly; Cell Size; Cells, Cultured; Endothelin-1; Hydrogen-Ion Concentration; Male; Myocardium; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers | 1997 |
Drug actions in preeclampsia: aspirin, but not magnesium chloride or dihydralazine, differentially inhibits cultured human trophoblast release of thromboxane and prostacyclin without affecting angiotensin II, endothelin-1, or leukotriene B4 secretion.
Topics: Angiotensin II; Antihypertensive Agents; Aspirin; Cells, Cultured; Cyclooxygenase Inhibitors; Dihydralazine; Endothelin-1; Epoprostenol; Female; Humans; Leukotriene B4; Magnesium Chloride; Pre-Eclampsia; Pregnancy; Thromboxane B2; Trophoblasts | 1997 |
Endothelial vasoconstrictor prostanoids modulate contractions to acetylcholine and ANG II in Ren-2 rats.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Body Weight; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Mice; Norepinephrine; Potassium Chloride; Prostaglandins; Rats; Rats, Sprague-Dawley; Renin; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Expression of guanylyl cyclase-A/atrial natriuretic peptide receptor blocks the activation of protein kinase C in vascular smooth muscle cells. Role of cGMP and cGMP-dependent protein kinase.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Carcinogens; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Guanylate Cyclase; Muscle, Smooth, Vascular; Peptide Fragments; Protein Kinase C; Rats; Receptors, Atrial Natriuretic Factor; Tetradecanoylphorbol Acetate; Tetrahydroisoquinolines; Transfection | 1997 |
Effects of chronic ETA-receptor blockade in angiotensin II-induced hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Thromboxane A2; Vasoconstrictor Agents | 1997 |
Endothelin-1 acts through ETA receptors to stimulate aldosterone secretion by the rat adrenal gland.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Binding Sites; Endothelin Receptor Antagonists; Endothelin-1; In Vitro Techniques; Kinetics; Peptides, Cyclic; Radioligand Assay; Rats; Receptor, Endothelin A; Receptors, Endothelin; Zona Glomerulosa | 1997 |
Modulation by angiotensin II of endothelial cell control of DNA synthesis in human mesangial cells.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Bosentan; Cell Division; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; DNA; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Epoprostenol; Glomerular Mesangium; Humans; Indomethacin; Sulfonamides; Thymidine; Umbilical Veins | 1997 |
Reversing congestive heart failure with endothelin receptor antagonists.
Topics: Aging; Angiotensin II; Animals; Bosentan; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Mice; Mice, Transgenic; Rabbits; Receptors, Endothelin; Sulfonamides | 1997 |
Regulation of bFGF expression and ANG II secretion in cardiac myocytes and microvascular endothelial cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Coronary Circulation; Endothelin-1; Endothelium, Vascular; Fibroblast Growth Factor 2; Heart Ventricles; Microcirculation; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1997 |
Radial artery has higher receptor-mediated contractility but similar endothelial function compared with mammary artery.
Topics: Angiotensin II; Calcimycin; Endothelin-1; Endothelium, Vascular; Humans; In Vitro Techniques; Ionophores; Mammary Arteries; Radial Artery; Receptors, Angiotensin; Receptors, Endothelin; Substance P; Vascular Patency; Vasoconstriction | 1997 |
Peptidergic modulation of the sympathetic contraction in the rabbit ear artery: effects of temperature.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Arginine Vasopressin; Arteries; Cold Temperature; Dose-Response Relationship, Drug; Ear; Electric Stimulation; Endothelin-1; Hot Temperature; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Peptides; Phentolamine; Rabbits; Sympatholytics; Tetrodotoxin; Vasoconstrictor Agents | 1997 |
Trophic effect of angiotensin II in neonatal rat cardiomyocytes: role of endothelin-1 and non-myocyte cells.
Topics: Angiotensin II; Animals; Animals, Newborn; Anti-Arrhythmia Agents; Biphenyl Compounds; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; GTP-Binding Proteins; Heart; Imidazoles; Inositol; Inositol Phosphates; Isotope Labeling; Losartan; Myocardium; Peptide Fragments; Peptides, Cyclic; Pertussis Toxin; Phenylalanine; Rats; Rats, Wistar; Tetrazoles; Vasoconstrictor Agents; Virulence Factors, Bordetella | 1997 |
Endothelin-1 alters the contractile phenotype of cultured embryonic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Cells, Cultured; Chick Embryo; DNA, Recombinant; Embryonic and Fetal Development; Endothelin-1; Genetic Variation; Gizzard, Avian; Isomerism; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Myosin Heavy Chains; Myosin Light Chains; Phenotype | 1997 |
Expression of a recombinant preproendothelin-1 gene in arteries stimulates vascular contractility.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Cells, Cultured; Endothelin-1; Endothelins; Gene Expression; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Protein Precursors; Protein Processing, Post-Translational; Rats; Swine; Transfection; Vasoconstriction | 1997 |
Stretch-induced MAP kinase activation in cardiomyocytes of angiotensinogen-deficient mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Targeting; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Peptides, Cyclic; Renin-Angiotensin System; Tetrazoles | 1997 |
Stretch-induced VEGF expression in the heart.
Topics: Angiotensin II; Animals; Antibodies; Catheterization; Diastole; Endothelial Growth Factors; Endothelin Receptor Antagonists; Endothelin-1; Heart; In Vitro Techniques; Lymphokines; Male; Myocardial Ischemia; Myocardium; Peptides, Cyclic; Protein Kinase C; Rats; Rats, Sprague-Dawley; RNA, Messenger; Saralasin; Staurosporine; Transcription, Genetic; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1997 |
[Secretion of endothelin-1 by cultured human normal adrenal cells].
Topics: Adrenal Glands; Adult; Aldosterone; Angiotensin II; Cells, Cultured; Endothelin-1; Humans; Hydrocortisone; Male; Vasoconstrictor Agents | 1996 |
G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60c-src and p21ras.
Topics: Angiotensin II; Animals; Antibodies; Aorta; Becaplermin; Biphenyl Compounds; Cell Division; Cells, Cultured; DNA; Electroporation; Endothelin-1; GTP-Binding Proteins; Imidazoles; Kinetics; Losartan; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Proto-Oncogene Proteins p21(ras); Proto-Oncogene Proteins pp60(c-src); Rats; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Endothelin; Receptors, Platelet-Derived Growth Factor; Receptors, Thrombin; Tetrazoles; Thrombin | 1997 |
Role for endothelin-1 in angiotensin II-mediated hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Serotonin; Staining and Labeling; Tetrazoles; Time Factors; Vasoconstrictor Agents | 1997 |
Nitric oxide modulates basal and endothelin-induced coronary artery vascular smooth muscle cell proliferation and collagen levels.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Collagen; Coronary Vessels; Endothelin-1; Endothelium, Vascular; Extracellular Matrix; Muscle, Smooth, Vascular; Nitric Oxide; Swine; Sydnones; Vasodilator Agents | 1997 |
Humoral factor(s) produced by pressure overload enhance cardiac hypertrophy and natriuretic peptide expression.
Topics: Angiotensin II; Animals; Aortic Coarctation; Atrial Natriuretic Factor; Atrophy; Blood Pressure; Body Weight; Cardiomegaly; Endothelin-1; Heart Rate; Heart Transplantation; Hypertension; Male; Myosins; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Rats; Rats, Inbred Lew; RNA, Messenger; Transcription, Genetic; Transplantation, Heterotopic; Transplantation, Isogeneic | 1997 |
Renal oxygenases: differential contribution to vasoconstriction induced by ET-1 and ANG II.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Arachidonic Acids; Cobalt; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Endothelin-1; Enzyme Inhibitors; Flavanones; Flavonoids; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Renal Circulation; Vasoconstriction | 1997 |
Elevated blood pressure in spontaneously hypertensive rats consuming a high sucrose diet is associated with elevated angiotensin II and is reversed by vanadium.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Dietary Sucrose; Endothelin-1; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred SHR; Vanadium | 1997 |
Angiotensin II-mediated growth and antigrowth effects in cultured neonatal rat cardiac myocytes and fibroblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Cells, Cultured; Endothelin-1; Fibroblasts; Growth Inhibitors; Growth Substances; Heart; Imidazoles; Inositol Phosphates; Losartan; Myocardium; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin | 1997 |
Cross-talk between receptor-mediated phospholipase C-beta and D via protein kinase C as intracellular signal possibly leading to hypertrophy in serum-free cultured cardiomyocytes.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Culture Media, Serum-Free; Down-Regulation; Endothelin-1; Histones; Immunoblotting; Isoenzymes; Myocardium; Phenylephrine; Phospholipase C beta; Phospholipase D; Protein Biosynthesis; Protein Kinase C; Proteins; Rats; Rats, Wistar; Signal Transduction; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1997 |
Enhanced constrictor responses of skeletal muscle arterioles during chronic myocardial infarction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arginine Vasopressin; Arterioles; Coronary Vessels; Endothelin-1; Hemodynamics; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Myocardial Infarction; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Reference Values; Thromboxane A2; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation.
Topics: Angiotensin II; Animals; Aorta; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Femoral Artery; In Vitro Techniques; Iodine Radioisotopes; Kidney; Male; Metalloendopeptidases; Muscle Contraction; Phenylpropionates; Pyrimidines; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Receptors, Endothelin | 1997 |
Cardiac microdialysis.
Topics: Angiotensin II; Animals; Endothelin-1; Extracellular Space; Heart; Hydroxyl Radical; Microdialysis; Myocardial Ischemia; Neuropeptide Y; Norepinephrine | 1998 |
Uncoupling of calcium mobilization and entry pathways in endothelin-stimulated pituitary lactotrophs.
Topics: Action Potentials; Angiotensin II; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Endothelin-1; Female; Membrane Potentials; Nifedipine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone | 1997 |
Comparison of nitroprusside and nitroglycerin in inhibition of angiotensin II and other vasoconstrictor-mediated contraction in human coronary bypass conduits.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Coronary Artery Bypass; Endothelin-1; Female; Humans; In Vitro Techniques; Male; Mammary Arteries; Nitroglycerin; Nitroprusside; Vasoconstriction; Vasodilator Agents | 1997 |
Effect of continuous regional vasoactive agent infusion on liver metastasis blood flow.
Topics: Angiotensin II; Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Disease Models, Animal; Endothelin-1; Infusions, Intra-Arterial; Laser-Doppler Flowmetry; Liver Circulation; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 1997 |
Effects of second-hand smoke and gender on infarct size of young rats exposed in utero and in the neonatal to adolescent period.
Topics: Angiotensin II; Animals; Animals, Newborn; Body Weight; Endothelin-1; Female; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Pregnancy; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Sex Factors; Tobacco Smoke Pollution | 1997 |
Significance of ventricular myocytes and nonmyocytes interaction during cardiocyte hypertrophy: evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cattle; Coculture Techniques; Culture Media, Conditioned; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy; Lipoproteins, LDL; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Paracrine Communication; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Transforming Growth Factor beta; Ventricular Function | 1997 |
Endothelin attenuates apoptosis in human smooth muscle cells.
Topics: Angiotensin II; Annexin A5; Apoptosis; Atrasentan; Cell Survival; DNA Fragmentation; Endothelin Receptor Antagonists; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Male; Muscle, Smooth; Paclitaxel; Pericardium; Phosphatidylserines; Propidium; Prostate; Pyrrolidines | 1997 |
Bosentan prevents preglomerular alterations during angiotensin II hypertension.
Topics: Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Endothelin-1; Hypertension; Kidney Glomerulus; Male; Microscopy, Video; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides; Systole | 1997 |
Effects of the dual metallopeptidase inhibitor, MDL 100,240, on regional haemodynamic responses to vasoactive peptides in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzazepines; Bradykinin; Endothelin-1; Hemodynamics; Male; Neprilysin; Protease Inhibitors; Pyridines; Rats | 1997 |
Angiotensin II and endothelin-1 increase fibroblast growth factor-2 mRNA expression in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Culture Media, Serum-Free; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Endothelin-1; Fibroblast Growth Factor 2; Gene Expression Regulation; Muscle, Smooth, Vascular; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Inbred WKY; RNA, Messenger | 1998 |
Hemodynamic effect of amrinone depends on pretreatment vascular resistance in patients with evolving congestive heart failure: correlation between vascular resistance and neurohormonal activity.
Topics: Aged; Amrinone; Angiotensin II; Biomarkers; Cardiotonic Agents; Endothelin-1; Female; Heart Failure; Hemodynamics; Humans; Male; Norepinephrine; Statistics as Topic; Vascular Resistance | 1998 |
Impaired endothelin-1 release in tilt-induced syncope.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Catecholamines; Endothelin-1; Female; Heart Rate; Humans; Male; Middle Aged; Signal Processing, Computer-Assisted; Syncope; Tilt-Table Test | 1998 |
Oestrogen and progesterone inhibit the stimulated production of endothelin-1.
Topics: Angiotensin II; Animals; Aorta; Cattle; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Culture Media; Culture Media, Serum-Free; Endothelin-1; Endothelium, Vascular; Estradiol; Female; Gene Expression Regulation; Half-Life; Humans; Progesterone; Promoter Regions, Genetic; Protein Biosynthesis; Recombinant Fusion Proteins; RNA, Messenger; Transcription, Genetic; Transfection | 1998 |
Role of ion channels and exchangers in mechanical stretch-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Cytoplasm; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Guanidines; Hydrogen-Ion Concentration; Ion Channels; MAP Kinase Kinase 1; Mechanoreceptors; Mitogen-Activated Protein Kinase Kinases; Muscle Proteins; Peptides, Cyclic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Rats; Rats, Wistar; Signal Transduction; Sodium-Hydrogen Exchangers; Sulfones; Tetrazoles | 1998 |
Constrictor responses of the rat basilar artery during diabetes mellitus.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Arginine Vasopressin; Basilar Artery; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Thromboxanes; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Molecular characterization of a dual endothelin-1/Angiotensin II receptor.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Base Sequence; Binding Sites; Brain Chemistry; DNA, Complementary; Endothelin-1; Evolution, Molecular; Gene Library; Models, Genetic; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides, Antisense; Rats; Receptor, Endothelin A; Receptors, Angiotensin; Receptors, Endothelin; Transfection | 1998 |
Effect of the endothelin family of peptides on human coronary artery smooth-muscle cell migration.
Topics: Angiotensin II; Cell Movement; Cells, Cultured; Coronary Vessels; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Humans; Muscle, Smooth, Vascular; Peptides, Cyclic; Platelet-Derived Growth Factor; Protein Precursors; Receptor, Endothelin A | 1998 |
Differential modulation of the renal and myocardial endothelin system by angiotensin II in Vivo. Effects of chronic selective ETA receptor blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Endothelin Receptor Antagonists; Endothelin-1; Heart; Kidney; Male; Myocardium; Phenylpropionates; Pyrimidines; Rats; Rats, Inbred WKY; Receptor, Endothelin A | 1998 |
Endothelin-1 expression in hearts of transgenic hypertensive mice overexpressing angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Progression; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Humans; Hypertension; Indans; Male; Mice; Mice, Transgenic; Myocardium; Polymerase Chain Reaction; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 1998 |
Autocrine/paracrine determinants of strain-activated brain natriuretic peptide gene expression in cultured cardiac myocytes.
Topics: Angiotensin II; Animals; Antibodies; Autocrine Communication; Cells, Cultured; Culture Media, Conditioned; Endothelin-1; Gene Expression Regulation; Genes, Reporter; Humans; Losartan; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Paracrine Communication; Peptides, Cyclic; Promoter Regions, Genetic; Rats; RNA, Messenger; Sprains and Strains; Transfection; Transforming Growth Factor beta; Ventricular Function | 1998 |
Losartan but not verapamil inhibits angiotensin II-induced tissue endothelin-1 increase: role of blood pressure and endothelial function.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Data Interpretation, Statistical; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hypertension; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; Nitroprusside; Rats; Rats, Inbred WKY; Receptors, Endothelin; Time Factors; Vasoconstriction; Vasodilation; Vasodilator Agents; Verapamil | 1998 |
Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ETA/ETB receptor antagonist, in the hind-limb vascular bed of the cat.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Cats; Endothelin Receptor Antagonists; Endothelin-1; Hindlimb; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Vasoconstriction; Vasodilation; Vasopressins | 1998 |
Diacylglycerol molecular species in plasma membrane and microsomes change transiently with endothelin-1 treatment of glioma cells.
Topics: Angiotensin II; Animals; Bradykinin; Brain Neoplasms; Cell Membrane; Chromatography, High Pressure Liquid; Diglycerides; Endoplasmic Reticulum; Endothelin-1; Fibroblasts; Glioma; Humans; Membrane Lipids; Mice; Microsomes; Neurotensin; Phospholipids; Rats; Serotonin; Signal Transduction; Tumor Cells, Cultured | 1998 |
Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Renovascular; Infusions, Intravenous; Losartan; Radioimmunoassay; Receptor, Endothelin A; Sulfonamides; Vascular Resistance | 1998 |
Prostaglandins induce calcium influx in human spermatozoa.
Topics: Acrosome; Adult; Alprostadil; Angiotensin II; Atrial Natriuretic Factor; Body Fluids; Calcium; Calcium Channel Blockers; Calcium Channels; Culture Media; Cyclic AMP; Dihydropyridines; Dinoprost; Dinoprostone; Drug Interactions; Endothelin-1; Female; Humans; Infertility, Male; Ion Transport; Male; Ovarian Follicle; Pentoxifylline; Pertussis Toxin; Progesterone; Sperm Capacitation; Sperm-Ovum Interactions; Spermatozoa; Virulence Factors, Bordetella | 1998 |
Alterations in basal protein kinase C activity modulate renal afferent arteriolar myogenic reactivity.
Topics: 4-Aminopyridine; Alkaloids; Angiotensin II; Animals; Arterioles; Benzophenanthridines; Blood Pressure; Delayed Rectifier Potassium Channels; Endothelin-1; Enzyme Inhibitors; Hydronephrosis; Kidney; Male; Muscle, Smooth, Vascular; Perfusion; Phenanthridines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Potassium Chloride; Protein Kinase C; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetradecanoylphorbol Acetate; Vasoconstriction | 1998 |
In situ observation of living pericytes in rat retinal capillaries.
Topics: Actins; Angiotensin II; Animals; Bradykinin; Capillaries; Carbachol; Endothelin-1; Female; Histamine; Immunohistochemistry; Male; Microscopy, Video; Rats; Rats, Wistar; Retinal Vessels; Vasoconstriction | 1998 |
Renoprotective effect of contemporary blocking of angiotensin II and endothelin-1 in rats with membranous nephropathy.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelin-1; Glomerulonephritis; Indoles; Kidney; Male; Phenylpropionates; Proteinuria; Pyrimidines; Rats; Rats, Sprague-Dawley | 1998 |
Angiotensin II and endothelin in chronic glomerulonephritis.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chronic Disease; Endothelin-1; Glomerulonephritis; Rats | 1998 |
[Endothelial dysfunction and angiotensin-converting enzyme inhibitors in coronary disease].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Coronary Disease; Endothelin-1; Endothelium, Vascular; Humans; Nitric Oxide; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Effects of losartan and captopril on endothelin-1 production in blood vessels and glomeruli of rats with reduced renal mass.
Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Captopril; Endothelin-1; Kidney Failure, Chronic; Kidney Glomerulus; Losartan; Male; Nephrectomy; Rats; Rats, Sprague-Dawley | 1998 |
Extending the targets for antihypertensive drugs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Humans; Losartan; Neprilysin; Renin; Renin-Angiotensin System; Vasopressins | 1998 |
Effect of heating on the hemodynamic responses to vasoactive agents.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Blood Pressure; Body Temperature; Endothelin-1; Hemodynamics; Hot Temperature; Male; Neuropeptides; Norepinephrine; Phenylephrine; Pituitary Adenylate Cyclase-Activating Polypeptide; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
Autacoid interactions in the regulation of blood flow in the human placenta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Drug Interactions; Eicosanoids; Endothelin-1; Enzyme Inhibitors; Female; Fetus; Free Radical Scavengers; Humans; Nitric Oxide; Nitroarginine; Placenta; Placental Circulation; Pregnancy; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1998 |
[The decrease of gastric mucosal blood flow in obstructive jaundice under stress].
Topics: Angiotensin II; Animals; Cholestasis; Cold Temperature; Endothelin-1; Gastric Mucosa; Male; Rats; Rats, Wistar; Receptors, Histamine H2; Regional Blood Flow; Stomach Ulcer; Stress, Physiological | 1997 |
Angiotensin and endothelin: messengers that couple ventricular stretch to the Na+/H+ exchanger and cardiac hypertrophy.
Topics: Angiotensin II; Cardiomegaly; Endothelin-1; Humans; Myocardium; Signal Transduction; Sodium-Hydrogen Exchangers | 1998 |
Production and secretion of adrenomedullin in cultured rat cardiac myocytes and nonmyocytes: stimulation by interleukin-1beta and tumor necrosis factor-alpha.
Topics: Adrenomedullin; Angiotensin II; Animals; Atrial Natriuretic Factor; Blotting, Northern; Cells, Cultured; Culture Media; Endothelin-1; Heart; Interleukin-1; Myocardium; Peptides; Phenylephrine; Rats; Rats, Wistar; RNA, Messenger; Stimulation, Chemical; Tumor Necrosis Factor-alpha | 1998 |
Effects of vasoactive agents in healthy and diseased human saphenous veins.
Topics: Angiotensin II; Chronic Disease; Endothelin-1; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Saphenous Vein; Vasoconstrictor Agents; Venous Insufficiency | 1998 |
Novel strategies to retard renal disease progression: combining ACE inhibition with endothelin receptor blocking?
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Endothelin Receptor Antagonists; Endothelin-1; Humans; Kidney Diseases | 1998 |
Role of angiotensin II, endothelin-1, and nitric oxide in HgCl2-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Blood Urea Nitrogen; Chromium; Creatinine; Disease Progression; Endothelin-1; Female; Immunohistochemistry; Kidney Tubules; Mercuric Chloride; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Tumor Necrosis Factor-alpha | 1998 |
Cyclooxygenase inhibition reveals synergistic action of vasoconstrictors on mesangial cell growth.
Topics: Analysis of Variance; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Glomerular Mesangium; Indomethacin; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasopressins | 1998 |
Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF-beta 1 and endothelin-1 from fibroblasts.
Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Blotting, Western; Cardiomegaly; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Endothelin-1; Fibroblasts; Microscopy, Fluorescence; Myocardium; Paracrine Communication; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Transforming Growth Factor beta; Vasoconstrictor Agents | 1998 |
Endothelin-1 is elevated in monocrotaline pulmonary hypertension.
Topics: Angiotensin II; Animals; Drug Combinations; Endothelin-1; Endothelins; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Lung; Male; Monocrotaline; Oligopeptides; omega-N-Methylarginine; Peptides, Cyclic; Piperidines; Rats; Rats, Sprague-Dawley; Vasoconstriction | 1999 |
Relationship between endothelin-1 extraction in the peripheral circulation and systemic vascular resistance in patients with severe congestive heart failure.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Endothelin-1; Female; Femoral Artery; Femoral Vein; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Pulmonary Wedge Pressure; Severity of Illness Index; Vascular Resistance | 1999 |
Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1, and thrombin.
Topics: 3T3 Cells; Amino Acid Sequence; Angiotensin II; Animals; Aorta; Base Sequence; Cells, Cultured; Cloning, Molecular; COS Cells; Culture Media, Conditioned; DNA; Endothelin-1; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Humans; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thrombin; Transfection | 1999 |
Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Angiotensin II; Animals; Calcimycin; Calcium Channels; Chloride Channels; Endothelin-1; Glyburide; In Vitro Techniques; Male; Niflumic Acid; Nitrobenzoates; Peptides; Pulmonary Artery; Rats; Rats, Wistar; Uridine Triphosphate; Vasoconstriction; Vasodilation | 1999 |
Angiotensin II increases the release of endothelin-1 from human cultured endothelial cells but does not regulate its circulating levels.
Topics: Adult; Angiotensin II; Cell Culture Techniques; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Receptors, Angiotensin | 1999 |
[Effects of hypoxia and taurine on vasoconstriction peptides from cultured bovine pulmonary arterial endothelial cells].
Topics: Angiotensin II; Animals; Cattle; Cell Hypoxia; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Pulmonary Artery; RNA, Messenger; Taurine | 1997 |
An experimental study of cardiac natriuretic peptides as markers of development of congestive heart failure.
Topics: Aldosterone; Angiotensin II; Animals; Atrial Natriuretic Factor; Biomarkers; Endothelin-1; Epinephrine; Female; Heart Failure; Male; Myocardium; Natriuretic Peptide, Brain; Norepinephrine; Pacemaker, Artificial; Protein Precursors; Renin; Swine | 1998 |
Heart failure induced by pheochromocytoma: laparoscopic treatment and intraoperative changes of several new cardiovascular hormones.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Endothelin-1; Epinephrine; Female; Heart Failure; Humans; Laparoscopy; Monitoring, Intraoperative; Norepinephrine; Pheochromocytoma; Protein Precursors | 1999 |
Angiotensin II-mediated potentiation of endothelin-1-evoked bronchial contractions: a role for leukotrienes?
Topics: Angiotensin II; Animals; Bronchi; Cattle; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Indazoles; Indoles; Leukotriene Antagonists; Leukotriene D4; Vasoconstrictor Agents | 1999 |
Angiotensin II interacts with prostaglandin F2alpha and endothelin-1 as a local luteolytic factor in the bovine corpus luteum in vitro.
Topics: Abortifacient Agents, Nonsteroidal; Angiotensin II; Animals; Calcimycin; Cattle; Corpus Luteum; Dinoprost; Dose-Response Relationship, Drug; Endothelin-1; Female; In Vitro Techniques; Luteolytic Agents; Microdialysis; Pregnancy; Tetradecanoylphorbol Acetate; Vasoconstrictor Agents | 1999 |
High-dose enoximone to evaluate reversibility of pulmonary hypertension: is there a diagnostic value of neurohormonal measurements?
Topics: Angiotensin II; Atrial Natriuretic Factor; Biomarkers; Cardiac Catheterization; Catecholamines; Endothelin-1; Enoximone; Female; Heart Failure; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Peptidyl-Dipeptidase A; Phosphodiesterase Inhibitors; Prognosis; Pulmonary Artery; Pulmonary Veins; Severity of Illness Index | 1999 |
Vasoactive hormones induce nitric oxide synthase mRNA expression and nitric oxide production in human endothelial cells and monocytes.
Topics: Adult; Angiotensin II; Dopamine; Electron Spin Resonance Spectroscopy; Endothelin-1; Endothelium, Vascular; Epinephrine; Female; Gene Expression; Humans; Liver; Monocytes; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 1999 |
On the regulation of tone in vasa vasorum.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Aorta; Bradykinin; Calcitonin Gene-Related Peptide; Cattle; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isoproterenol; Norepinephrine; Prostaglandin Endoperoxides, Synthetic; Substance P; Swine; Vasa Vasorum; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Role of insulin preincubation in the contractile reactivity of rat aortic rings.
Topics: Angiotensin II; Animals; Aorta; Arginine Vasopressin; Endothelin-1; Enzyme Inhibitors; Epoprostenol; Indomethacin; Insulin; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Vasoconstriction | 1998 |
Concentrations of angiotensin II, endothelin-1, and BNP in the coronary sinus and ascending aorta of patients with heart disease.
Topics: Aged; Angiotensin II; Aorta; Biomarkers; Cardiac Catheterization; Coronary Vessels; Endothelin-1; Female; Heart Failure; Humans; Male; Middle Aged; Natriuretic Peptide, Brain | 1999 |
Anomalous origin of the left coronary artery from the pulmonary artery.
Topics: Angiotensin II; Biomarkers; Endothelin-1; Female; Heart Failure; Humans; Natriuretic Peptide, Brain | 1999 |
Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes.
Topics: Angiotensin II; Animals; Antigens, CD; Autocrine Communication; Calcium; Carcinogens; Cardiomegaly; Cells, Cultured; Cytokine Receptor gp130; DNA-Binding Proteins; Endothelin-1; Gene Expression Regulation, Enzymologic; Interleukin-6; Janus Kinase 1; Janus Kinase 2; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Paracrine Communication; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Rats; Rats, Wistar; Signal Transduction; Sodium-Potassium-Exchanging ATPase; STAT1 Transcription Factor; STAT3 Transcription Factor; Stress, Mechanical; Tetradecanoylphorbol Acetate; Trans-Activators; TYK2 Kinase | 1999 |
Endothelin and angiotensin mediate most glomerular responses to nitric oxide inhibition.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Kidney Glomerulus; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides | 1999 |
Effects of sustained low-flow perfusion on the response to vasoconstrictor agents in postnatal intestine.
Topics: Angiotensin II; Animals; Animals, Newborn; Blood Circulation; Blood Vessels; Endothelin-1; In Vitro Techniques; Intestines; Norepinephrine; Swine; Vasoconstrictor Agents | 1999 |
Endothelial dysfunction in the aorta of transgenic rats harboring the mouse Ren-2 gene.
Topics: Acetylcholine; Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Blood Pressure; Body Weight; Endothelin-1; Endothelins; Endothelium, Vascular; Hypertension; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Norepinephrine; Protein Precursors; Rats; Rats, Sprague-Dawley; Renin | 1999 |
The effects of short-term nifedipine treatment on responsiveness of aortic rings of cadmium-hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cadmium Chloride; Calcium Channel Blockers; Disease Models, Animal; Endothelin-1; Follow-Up Studies; Hypertension; Male; Nifedipine; Norepinephrine; Random Allocation; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Gene transfer of endothelial nitric oxide synthase to the lung of the mouse in vivo. Effect on agonist-induced and flow-mediated vascular responses.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenoviridae; Angiotensin II; Animals; Antimetabolites, Antineoplastic; beta-Galactosidase; Bleomycin; Blood Flow Velocity; Blood Pressure; Bradykinin; Cyclic GMP; Endothelin-1; Gene Transfer Techniques; Genes, Reporter; Hypertension, Pulmonary; Hypoxia; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Phosphodiesterase Inhibitors; Pulmonary Alveoli; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Purinones; Sympathomimetics; Vasoconstrictor Agents | 1999 |
Vascular mitogen-activated protein kinase activity is enhanced via angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Hypertension; Losartan; Male; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1999 |
Induction of Egr-1 mRNA and protein by endothelin 1, angiotensin II and norepinephrine in neonatal cardiac myocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelin-1; Fluorescent Antibody Technique, Direct; Gene Expression Regulation; Immediate-Early Proteins; Microscopy, Fluorescence; Myocardium; Norepinephrine; Protein Biosynthesis; Rats; RNA, Messenger; Signal Transduction; Transcription Factors | 1999 |
Developmental conversion of inotropism by endothelin I and angiotensin II from positive to negative in mice.
Topics: Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Antihypertensive Agents; Azoles; Biphenyl Compounds; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; In Vitro Techniques; Mice; Myocardial Contraction; Peptides, Cyclic; Receptor, Endothelin A; Ventricular Function | 1999 |
Endothelin receptor antagonists reduce the pressor effects of angiotensin II into the periaqueductal gray area of rats.
Topics: Angiotensin II; Animals; Azepines; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Indans; Indoles; Male; Oligopeptides; Periaqueductal Gray; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 1999 |
The impact of vasoactive peptides on nitric oxide production in cultured sympathetic neurons.
Topics: Angiotensin II; Animals; Arginine; Calcium; Cells, Cultured; Chick Embryo; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Microelectrodes; Microscopy, Fluorescence; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sympathetic Nervous System | 1999 |
Differentiation of the peptidergic vasoregulatory response to standardized splanchnic hypoperfusion by acute hypovolaemia or sepsis in anaesthetized pigs.
Topics: Acute Disease; Anesthesia; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Escherichia coli Infections; Female; Femoral Vein; Hemorrhage; Hypovolemia; Male; Neuropeptides; Portal Vein; Sepsis; Splanchnic Circulation; Swine; Vasoconstrictor Agents | 1999 |
Chronic hypoxia alters effects of endothelin and angiotensin on K+ currents in pulmonary arterial myocytes.
Topics: Angiotensin II; Animals; Chronic Disease; Electric Conductivity; Endothelin-1; Heart Ventricles; Hypoxia; Male; Muscle, Smooth, Vascular; Myocardium; Organ Size; Potassium Channels; Pulmonary Artery; Rats; Rats, Wistar | 1999 |
Adrenal capillary endothelial cells stimulate aldosterone release through a protein that is distinct from endothelin.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Bradykinin; Capillaries; Cattle; Coculture Techniques; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hormone Antagonists; Oligopeptides; Osmolar Concentration; Pronase; Receptor, Endothelin B; Steroids; Time Factors; Zona Fasciculata; Zona Glomerulosa | 1999 |
Effects of the angiotensin II antagonist losartan on endothelin-1 and norepinephrine plasma levels during cold pressor test in patients with chronic heart failure.
Topics: Aged; Aged, 80 and over; Angiotensin II; Antihypertensive Agents; Blood Pressure; Chronic Disease; Cold Temperature; Endothelin-1; Exercise Test; Female; Heart Failure; Heart Rate; Humans; Losartan; Male; Middle Aged; Norepinephrine; Sympathetic Nervous System; Vasoconstriction | 1999 |
Renal and vascular effects of chronic nitric oxide synthase inhibition: involvement of endothelin 1 and angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1999 |
Antagonistic effects of losartan on thromboxane A2-receptors in human isolated gastroepiploic artery and saphenous vein.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Humans; In Vitro Techniques; Indomethacin; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Potassium Chloride; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Saphenous Vein; Serotonin; Stomach | 1999 |
Effects of adrenomedullin on cultured rat cardiac myocytes and fibroblasts.
Topics: Adrenomedullin; Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Collagen; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Fibroblasts; Heart Ventricles; Myocardium; Peptides; Phosphodiesterase Inhibitors; Protein Biosynthesis; Rats; Vasodilator Agents | 1999 |
Evidence for a local endothelin-angiotensin-atrial natriuretic peptide systemin bovine mature follicles in vitro: effects on steroid hormones and prostaglandin secretion.
Topics: Androstenedione; Angiotensin II; Animals; Atrial Natriuretic Factor; Cattle; Endothelin-1; Estradiol; Female; Hormones; Luteinizing Hormone; Organ Culture Techniques; Ovarian Follicle; Progesterone; Prostaglandins; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; Receptors, Endothelin; RNA, Messenger | 1999 |
Plasma brain natriuretic peptide level as a biochemical marker of morbidity and mortality in patients with asymptomatic or minimally symptomatic left ventricular dysfunction. Comparison with plasma angiotensin II and endothelin-1.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Biomarkers; Endothelin-1; Female; Humans; Incidence; Male; Middle Aged; Natriuretic Peptide, Brain; Prognosis; Proportional Hazards Models; Radioimmunoassay; Retrospective Studies; Severity of Illness Index; Stroke Volume; Survival Rate; Ventricular Dysfunction, Left; Ventricular Pressure | 1999 |
Structural and functional assessment of small arteries in patients with chronic heart failure.
Topics: Acetylcholine; Adult; Aged; Analysis of Variance; Angiotensin II; Arteries; Bradykinin; Case-Control Studies; Dose-Response Relationship, Drug; Endothelin-1; Epoprostenol; Female; Heart Failure; Humans; Male; Middle Aged; Muscle, Skeletal; Myography; Natriuretic Peptide, Brain; Nitroprusside; Norepinephrine; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
Functional comparison of the human isolated femoral artery, internal mammary artery, gastroepiploic artery, and saphenous vein.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Arteries; Dose-Response Relationship, Drug; Endothelin-1; Femoral Artery; Humans; In Vitro Techniques; Leukotriene C4; Mammary Arteries; Norepinephrine; Potassium Chloride; Saphenous Vein; Sensitivity and Specificity; Stomach; Vasoconstriction; Vasoconstrictor Agents | 1999 |
Subendothelial cells from normal bovine arteries exhibit autonomous growth and constitutively activated intracellular signaling.
Topics: Angiotensin II; Animals; Anticoagulants; Aorta, Thoracic; Becaplermin; Blood Proteins; Cattle; Cell Division; Cell Size; Culture Media, Conditioned; Culture Media, Serum-Free; Cyclooxygenase 2; Dinoprostone; Endothelin-1; Endothelium, Vascular; Epoprostenol; Gene Expression Regulation, Enzymologic; GTP-Binding Proteins; Isoenzymes; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Paracrine Communication; Phospholipases A; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Tunica Media; Vasoconstrictor Agents | 1999 |
Hypertrophic stimuli augment expression of cMG1/ERF-1, a putative zinc-finger motif transcription factor, in rat cardiomyocytes.
Topics: Angiotensin II; Animals; Blotting, Northern; Butyrate Response Factor 1; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Gene Expression; Growth Inhibitors; Immediate-Early Proteins; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Myocardium; Protein Biosynthesis; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Stress, Mechanical; Time Factors; Transcription Factors; Tristetraprolin; Zinc Fingers | 1999 |
Cardiac endothelin and big endothelin in right-heart hypertrophy due to monocrotaline-induced pulmonary hypertension in rat.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Endothelins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Monocrotaline; Myocardium; Perfusion; Poisons; Protein Precursors; Rats; Rats, Sprague-Dawley | 1999 |
An autocrine or a paracrine role of adrenomedullin in modulating cardiac fibroblast growth.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenomedullin; Angiotensin II; Animals; Antibodies, Monoclonal; Autocrine Communication; Calcitonin Gene-Related Peptide; Cell Division; Cells, Cultured; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Humans; Miotics; Myocardium; Paracrine Communication; Peptide Fragments; Peptides; Protein Biosynthesis; Rats; Rats, Wistar | 1999 |
The effects of angiotensin II, endothelin-1, and protein kinase C inhibitor on DNA synthesis and intracellular calcium mobilization in vascular smooth muscle cells from young normotensive and spontaneously hypertensive rats.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Cells, Cultured; DNA; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Hypertension; Intracellular Fluid; Muscle, Smooth, Vascular; Phenanthridines; Protein Kinase C; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spectrometry, Fluorescence; Thymidine; Vasoconstriction | 1999 |
Obesity is associated with tissue-specific activation of renal angiotensin-converting enzyme in vivo: evidence for a regulatory role of endothelin.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Carotid Arteries; Cholesterol; Cyclooxygenase Inhibitors; Diet; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression Regulation, Enzymologic; Humans; Indomethacin; Kidney; Lung; Male; Mice; Mice, Inbred C57BL; Obesity; Organ Culture Techniques; Peptidyl-Dipeptidase A; Phenylpropionates; Protein Binding; Pyrimidines; Receptor, Endothelin A; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Identification of G protein-coupled signaling pathways in cardiac fibroblasts: cross talk between G(q) and G(s).
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Angiotensin II; Animals; Bradykinin; Calcium; Carbachol; Cardiotonic Agents; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Isoproterenol; Male; Myocardium; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor Cross-Talk; Signal Transduction; Sympathomimetics; Type C Phospholipases; Uridine Triphosphate; Vasoconstrictor Agents | 2000 |
Pharmacological characterization of mucin secretion from CHO-K1-hNK(1)R cells.
Topics: Angiotensin II; Animals; Benzamides; Biological Transport; CHO Cells; Cricetinae; Endothelin-1; Glucosamine; Humans; Methacholine Chloride; Mucins; Muscarinic Agonists; Neurokinin A; Peptide Fragments; Phenylephrine; Piperidines; Quinuclidines; Receptors, Neurokinin-1; Serotonin; Substance P; Transfection; Tritium; Vasoconstrictor Agents | 1999 |
Gastrointestinal osmoreceptors and renal sodium excretion in humans.
Topics: Adult; Angiotensin II; Atrial Natriuretic Factor; Digestive System Physiological Phenomena; Drinking; Endothelin-1; Humans; Intubation, Gastrointestinal; Isotonic Solutions; Kidney; Male; Saline Solution, Hypertonic; Sodium; Sodium Chloride; Water-Electrolyte Balance | 2000 |
RGS domain in the amino-terminus of G protein-coupled receptor kinase 2 inhibits Gq-mediated signaling.
Topics: Aluminum Compounds; Angiotensin II; beta-Adrenergic Receptor Kinases; Calcium; Cell Line; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Fluorides; Fura-2; GTP-Binding Protein Regulators; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Plasmids; Signal Transduction; Transfection | 2000 |
Simultaneous separation of angiotensin and endothelin peptide families by high-performance liquid chromatography: application to the specific radioimmunoassay measurement of angiotensin II or endothelin-1 from tissue.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Dogs; Endothelin-1; Hydrogen-Ion Concentration; Male; Molecular Sequence Data; Myocardium; Radioimmunoassay; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2000 |
Aging differentially modifies sensitivity of nerve blood flow to vasocontractile agents (endothelin-1, noradrenaline and angiotensin II) in sciatic nerve.
Topics: Aging; Angiotensin II; Animals; Arterioles; Blood Pressure; Endothelin-1; Norepinephrine; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vasoconstrictor Agents | 2000 |
Synergistic effects of AT(1) and ET(A) receptor blockade in a transgenic, angiotensin II-dependent, rat model.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Humans; Hypertension; Losartan; Phenylpropionates; Pyrimidines; Rats; Renin | 2000 |
Natriuretic peptide receptor-A negatively regulates mitogen-activated protein kinase and proliferation of mesangial cells: role of cGMP-dependent protein kinase.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelin-1; Enzyme Inhibitors; Fibroblast Growth Factors; Glomerular Mesangium; Guanylate Cyclase; Mitogen-Activated Protein Kinase 1; Peptide Fragments; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Atrial Natriuretic Factor; Tetrahydroisoquinolines; Thymidine; Time Factors; Transfection | 2000 |
Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat.
Topics: Aging; Angiotensin II; Animals; Endothelin-1; Enzyme Inhibitors; Hemodynamics; Hypertension, Renal; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Punctures; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation | 2000 |
Tissue angiotensin II and endothelin-1 modulate differently the response to flow in mesenteric resistance arteries of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Viscosity; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Imidazoles; Losartan; Mesenteric Arteries; Muscle Tonus; Perindopril; Phenylpropionates; Pyridines; Pyrimidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Splanchnic Circulation; Vascular Resistance; Vasodilation | 2000 |
Angiotensin II formation and endothelin clearance in ARDS patients in supine and prone positions.
Topics: Adult; Analysis of Variance; Angiotensin II; Critical Illness; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Hemodynamics; Humans; Male; Middle Aged; Prone Position; Renin; Respiratory Distress Syndrome; Severity of Illness Index; Supine Position | 2000 |
The activation of phospholipase D by endothelin-1, angiotensin II, and platelet-derived growth factor in vascular smooth muscle A10 cells is mediated by small G proteins of the ADP-ribosylation factor family.
Topics: ADP Ribose Transferases; ADP-Ribosylation Factors; Angiotensin II; Botulinum Toxins; Brefeldin A; Cell Line; Clostridium botulinum; Endothelin-1; Enzyme Activation; Gene Expression; Green Fluorescent Proteins; Humans; Luminescent Proteins; Monomeric GTP-Binding Proteins; Muscle, Smooth, Vascular; Mutation; Phospholipase D; Platelet-Derived Growth Factor; Recombinant Fusion Proteins; Transfection | 2000 |
Evidence for vasoconstriction mediated by the endothelin-B receptor in domestic swine.
Topics: Angiotensin II; Animals; Animals, Domestic; Atrasentan; Blood Pressure; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Femoral Artery; Protein Precursors; Pyrrolidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Swine; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2000 |
Plasma-levels of endothelin-1 and angiotensin-II and reactivity of arterial blood pressure to exogenous sympathomimetics and vasoactive peptides in rat model of malignant renal hypertension.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Pressure; Endothelin-1; Hypertension, Renovascular; Male; Norepinephrine; Rats; Rats, Wistar; Sympathomimetics; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Calcium and osmotic regulation of the Na+/H+ exchanger in neonatal ventricular myocytes.
Topics: Amiloride; Angiotensin II; Animals; Animals, Newborn; Calcium; Calmodulin; Cells, Cultured; CHO Cells; Choline; Cricetinae; Endothelin-1; Heart Ventricles; Imidazoles; Meglumine; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sodium-Hydrogen Exchangers; Sorbitol; Sulfonamides; Trifluoperazine; Water-Electrolyte Balance | 2000 |
Vascular reactivity of isolated thoracic aorta of the C57BL/6J mouse.
Topics: Acetylcholine; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Aorta, Thoracic; Dinoprost; Dopamine; Endothelin-1; Endothelium, Vascular; Histamine; In Vitro Techniques; Isometric Contraction; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Serotonin; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Zinc deficiency further increases the enhanced expression of endothelin-1 in glomeruli of the obstructed kidney.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Copper; Enalapril; Endothelin-1; Endothelins; Female; Gene Expression; Immunohistochemistry; In Situ Hybridization; Kidney Glomerulus; Peptidyl-Dipeptidase A; Protein Precursors; Rats; Rats, Sprague-Dawley; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin Diseases; Ureteral Obstruction; Zinc | 2000 |
Selective estrogen receptor modulators suppress mesangial cell collagen synthesis.
Topics: Angiotensin II; Animals; Cell Line, Transformed; Collagen; Endothelin-1; Estrogen Receptor beta; Estrogens; Glomerular Mesangium; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Pyrrolidines; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Thiophenes; Transcription Factor AP-1; Transcription, Genetic; Transforming Growth Factor beta; Up-Regulation | 2000 |
Endothelial dysfunction: the role and impact of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Coronary Disease; Endothelin-1; Endothelium, Vascular; Humans; Nitric Oxide; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Sympathetic Nervous System | 2000 |
Release of endothelin 1 and angiotensin II induced by percutaneous transluminal coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Angiotensin II; Atherectomy, Coronary; Coronary Vessels; Endothelin-1; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Myocardial Ischemia; Stents; Thrombomodulin; Treatment Outcome; von Willebrand Factor | 2000 |
Endothelin-1 stimulates aldosterone synthesis in Conn's adenomas via both A and B receptors coupled with the protein kinase C- and cyclooxygenase-dependent signaling pathways.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Adult; Aged; Aldosterone; Angiotensin II; Endothelin-1; Endothelins; Female; Humans; Indomethacin; Isoquinolines; Male; Middle Aged; Naphthalenes; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Pyrazoles; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Signal Transduction; Sulfonamides; Tumor Cells, Cultured | 2000 |
Different activation of vascular mitogen-activated protein kinases in spontaneously and DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Desoxycorticosterone; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Activation; Hypertension; In Vitro Techniques; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptides, Cyclic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Endothelin; Sodium Chloride; Vasoconstrictor Agents | 2000 |
Reduction of cardiac endothelin-1 by angiotensin II type 1 receptor antagonist in viral myocarditis of mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovirus Infections; Encephalomyocarditis virus; Endothelin-1; Female; Mice; Mice, Inbred C3H; Myocarditis; Organ Size; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Early sequence of cardiac adaptations and growth factor formation in pressure- and volume-overload hypertrophy.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Blood Pressure; Cardiac Volume; Cardiomegaly; Disease Models, Animal; Echocardiography; Endothelin-1; Female; Hemodynamics; In Situ Hybridization; Insulin-Like Growth Factor I; Male; Myocardium; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine | 2000 |
Coronary microvascular endothelial cells cosecrete angiotensin II and endothelin-1 via a regulated pathway.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Antibody Specificity; Cadmium; Cell Size; Cells, Cultured; Coronary Vessels; Cycloheximide; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Immunoblotting; Immunohistochemistry; Male; Microcirculation; Nitric Oxide Donors; Potassium; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents | 2000 |
Active and passive liver microvascular responses from angiotensin, endothelin, norepinephrine, and vasopressin.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Endothelin-1; Female; Infusions, Intravenous; Liver; Liver Circulation; Male; Microcirculation; Norepinephrine; Portal Vein; Rabbits; Ultrasonography; Vascular Resistance; Vasopressins | 2000 |
Effects of combined angiotensin II and endothelin receptor blockade with developing heart failure: effects on left ventricular performance.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bosentan; Cardiac Pacing, Artificial; Combined Modality Therapy; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Myocardial Contraction; Norepinephrine; Receptor, Endothelin A; Renin; Sulfonamides; Swine; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left | 2000 |
Transcardiac extraction of circulating endothelin-1 across the failing heart.
Topics: Angiotensin II; Aorta; Coronary Vessels; Endothelin-1; Heart Failure; Hemodynamics; Humans; Norepinephrine; Peptide Fragments; Procollagen; Reference Values; Ventricular Function, Left | 2000 |
Tyrphostin-23 enhances steroid-hormone secretion from dispersed human and rat adrenocrotical cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Corticosterone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Inhibitors; Humans; Hydrocortisone; Isoquinolines; Male; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Tyrphostins | 2000 |
Involvement of angiotensin II and endothelin-1 in the development of submandibular gland hypertrophy in response to isoproterenol in rats.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Dobutamine; Enalapril; Endothelin-1; Hypertrophy; Isoproterenol; Male; Rats; Rats, Wistar; Submandibular Gland | 2000 |
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Bradykinin; Bucladesine; Cerebral Cortex; Chelating Agents; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Paxillin; Pertussis Toxin; Phosphoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Regulation of the myocardial endothelin system by angiotensin-II and losartan.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Endothelin-1; Endothelins; Gene Expression Regulation; Losartan; Male; Myocardium; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger | 2000 |
Endothelin stimulates glucose uptake via activation of endothelin-A receptor in neonatal rat cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Endothelin-1; Glucose; Glucose Transporter Type 4; Insulin; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin | 2000 |
Lack of involvement of endothelin-1 in angiotensin II-induced contraction of the isolated rat tail artery.
Topics: Angiotensin II; Animals; Arteries; Calcium; Endothelin-1; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tail; Vasoconstriction; Vasoconstrictor Agents | 2000 |
Hormonal changes in brain death and immune activation in the donor.
Topics: Adult; Angiotensin II; Antigens, CD; Brain Death; Cytokines; Endothelin-1; Epinephrine; Female; Hormones; Humans; Interleukins; Male; Middle Aged; Norepinephrine; Pituitary Hormones; Receptors, Cytokine; Receptors, Interleukin-2; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Renin; Tissue Donors | 2000 |
Renal fibrosis in mice treated with human recombinant transforming growth factor-beta2.
Topics: Angiotensin II; Animals; Corrosion Casting; Endothelin-1; Fibrosis; Glomerular Filtration Rate; Humans; Hypoxia; Ischemia; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Procollagen; Recombinant Proteins; Transforming Growth Factor beta; Transforming Growth Factor beta2; Vasoconstriction | 2000 |
Hydrocortisone abolishes the angiotensin II-mediated potentiation of endothelin-1 in bovine bronchi.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Bronchoconstriction; Bronchoconstrictor Agents; Cattle; Culture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Hydrocortisone; Methacholine Chloride | 2001 |
Acute hypertension inhibits thirst stimulated by ANG II, hyperosmolality, or hypovolemia in rats.
Topics: Acute Disease; Angiotensin II; Animals; Blood Pressure; Drinking; Drinking Behavior; Endothelin-1; Hypertension; Hypovolemia; Infusions, Intravenous; Male; Osmotic Pressure; Phenylephrine; Polyethylene Glycols; Potassium; Pressoreceptors; Rats; Rats, Sprague-Dawley; Saline Solution, Hypertonic; Sodium; Solvents; Thirst; Urine; Vasoconstrictor Agents | 2001 |
The effects of sarpogrelate on cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Endothelin-1; Fibroblasts; Heart Ventricles; Leucine; Myocardium; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Succinates; Tritium | 2000 |
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glycopeptides; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Renin | 2001 |
Neurohormonal regulation of myocardial cell apoptosis during the development of heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Cardiac Output, Low; Cytokines; Endothelin-1; Heart; Myocardium; Neurotransmitter Agents; Receptors, Adrenergic | 2001 |
Effects of salt intake and angiotensin II on vascular reactivity to endothelin-1.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Sodium, Dietary; Vasoconstrictor Agents | 2001 |
Insulin-like growth factor-binding protein-3 induces fetalization in neonatal rat cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Coronary Vessels; Disease Models, Animal; Disease Progression; Endothelin-1; Gene Expression Profiling; Gene Expression Regulation; Heart Ventricles; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Myocardial Infarction; Myocardium; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Oligonucleotide Array Sequence Analysis; Rats; RNA, Messenger; Transforming Growth Factor beta; Troponin I | 2000 |
Preeclamptic serum enhances endothelin-converting enzyme expression in cultured endothelial cells.
Topics: Adult; Angiotensin II; Aspartic Acid Endopeptidases; Blood Physiological Phenomena; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Epinephrine; Female; Humans; Inositol 1,4,5-Trisphosphate; Metalloendopeptidases; Pre-Eclampsia; Pregnancy; Reference Values; Vasoconstrictor Agents | 2001 |
Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle.
Topics: Angiotensin II; Animals; Endothelin-1; Endothelium; Female; Ferrets; Kinetics; Losartan; Male; Muscle Spindles; Myocardial Contraction; Octoxynol; Oligopeptides; Papillary Muscles; Peptides, Cyclic; Saralasin | 2001 |
Effects of TCV-116 on endothelin-1 and PDGF A-chain expression in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Body Weight; Collagen; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension; Male; Organ Size; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Ventricular Remodeling | 2001 |
Angiotensin II relaxes microvessels via the AT(2) receptor and Ca(2+)-activated K(+) (BK(Ca)) channels.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Imidazoles; In Vitro Techniques; Losartan; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Patch-Clamp Techniques; Peptides; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetraethylammonium; Vasodilation | 2001 |
Effects of potassium channel opener aprikalim on the receptor-mediated vasoconstriction in the human internal mammary artery.
Topics: Angiotensin II; Culture Techniques; Dose-Response Relationship, Drug; Endothelin-1; Humans; Mammary Arteries; Norepinephrine; Picolines; Potassium Channels; Pyrans; Receptors, Neurotransmitter; Serotonin; Vasoconstriction; Vasodilator Agents | 2001 |
Effect of N-acetyl-seryl-aspartyl-lysyl-proline on DNA and collagen synthesis in rat cardiac fibroblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Division; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Oligopeptides; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
Regulation of cardiac collagen: angiotensin and cross-talk with local growth factors.
Topics: Angiotensin II; Animals; Collagen; Endothelin-1; Gene Expression Regulation; Growth Substances; Heart; Humans; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
The role of ANG II and endothelin-1 in exercise-induced diastolic dysfunction in heart failure.
Topics: Acetamides; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Function, Left; Diastole; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Losartan; Nitroprusside; Physical Exertion; Reference Values; Vasodilation; Ventricular Function, Left | 2001 |
Characterization of RGS5 in regulation of G protein-coupled receptor signaling.
Topics: Angiotensin II; Calcium Channels; Calcium Signaling; Cell Line, Transformed; Endothelin-1; GTP-Binding Proteins; GTPase-Activating Proteins; Humans; Receptors, Angiotensin; Receptors, Cell Surface; RGS Proteins; Signal Transduction | 2001 |
Hemodynamic, renal, and endocrine responses to acute ET(A) blockade at different ANG II plasma levels.
Topics: Aldosterone; Angiotensin II; Animals; Creatinine; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Glomerular Filtration Rate; Hemodynamics; Infusions, Intravenous; Injections, Intravenous; Phenylpropionates; Protein Precursors; Pulmonary Circulation; Pyrimidines; Receptor, Endothelin A; Reference Values; Renin; Renin-Angiotensin System; Urodynamics; Vascular Resistance | 2001 |
Enhanced renal expression of preproendothelin mRNA during chronic angiotensin II hypertension.
Topics: Angiotensin II; Animals; Atrasentan; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Gene Expression Regulation; Glomerular Filtration Rate; Hemodynamics; Hypertension; Infusions, Intravenous; Kidney; Kidney Cortex; Kidney Medulla; Male; Protein Precursors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Renal Circulation; RNA, Messenger; Transcription, Genetic; Urodynamics | 2001 |
Activation of NF-kappaB in tubular epithelial cells of rats with intense proteinuria: role of angiotensin II and endothelin-1.
Topics: Analysis of Variance; Angiotensin II; Animals; Atrophy; Cell Line; Endothelin-1; Epithelial Cells; Female; Kidney Cortex; Kidney Tubules; Nephrectomy; Nephritis; NF-kappa B; Proteinuria; Rats; Rats, Inbred WKY | 2001 |
The role of angiotensin II, endothelin-1 and transforming growth factor-beta as autocrine/paracrine mediators of stretch-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Culture Media, Conditioned; Endothelin-1; Endothelium, Vascular; Fibroblasts; Gene Expression; Genes, fos; Muscle, Smooth, Vascular; Myocardium; Rats; Rats, Wistar; RNA, Messenger; Stress, Mechanical; Transforming Growth Factor beta; Vasoconstrictor Agents | 2001 |
Angiotensin II and serotonin potentiate endothelin-1-induced vascular smooth muscle cell proliferation.
Topics: Angiotensin II; Animals; Cell Count; Cell Division; Cells, Cultured; DNA; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Guanosine 5'-O-(3-Thiotriphosphate); Male; Muscle, Smooth, Vascular; Rabbits; Serotonin | 2001 |
Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Cardiomyopathy, Dilated; Cardiovascular Diseases; Chymases; Endothelin-1; Gene Expression; Gene Expression Regulation; Heart Ventricles; Immunohistochemistry; In Situ Hybridization; Insulin-Like Growth Factor I; Iodine Radioisotopes; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Platelet-Derived Growth Factor; Protein Precursors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Ventricular Function, Left | 2001 |
Paradoxically enhanced endothelin-B receptor-mediated vasoconstriction in conscious old monkeys.
Topics: Aging; Angiotensin II; Animals; Consciousness; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2001 |
[The effect of inhibition of nitric oxide synthesis on vasoregulatory factors in pregnant rats].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Endothelin-1; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pre-Eclampsia; Pregnancy; Random Allocation; Rats; Rats, Wistar; Vasodilation | 1999 |
[The protective effect of captopril during myocardial ischemia and reperfusion and its mechanism].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogs; Endothelin-1; Female; Heart Function Tests; Male; Myocardial Reperfusion Injury; Myocardium; Random Allocation | 1998 |
Combined effects of AT(1) and ET(A) receptor antagonists, candesartan, and A-127722 in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Desoxycorticosterone; Disease Models, Animal; Drug Therapy, Combination; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Natriuresis; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2000 |
[The role of nitric oxide in the prevention of myocardial hypertrophic response and its mechanisms].
Topics: Academic Dissertations as Topic; Angiotensin II; Animals; Cardiomyopathy, Hypertrophic; Cyclic GMP; Endothelin-1; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Proto-Oncogene Proteins c-fos; Rats; Ventricular Pressure | 2000 |
Angiotensin regulates endothelin-B receptor in rat inner medullary collecting duct.
Topics: Angiotensin II; Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Endothelin-1; In Vitro Techniques; Kidney Medulla; Kidney Tubules, Collecting; Male; Protein Binding; Protein Kinase C; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger | 2001 |
Effect of chronic hypoxia on agonist-induced tone and calcium signaling in rat pulmonary artery.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Caffeine; Calcium; Calcium Signaling; Chronic Disease; Endothelin-1; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Indoles; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Wistar; Reference Values; Vasoconstriction; Vasodilator Agents; Vasomotor System | 2001 |
Cysteinyl leukotrienes mediate enhanced vasoconstriction to angiotensin II but not endothelin-1 in SHR.
Topics: Angiotensin II; Animals; Benzoquinones; Endothelin-1; Hypertension; Leukotriene Antagonists; Leukotrienes; Lipoxygenase Inhibitors; Male; Potassium Chloride; Propionates; Quinolines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Vasoconstriction | 2001 |
Angiotensin-II and endothelin-1 levels in children with renoprival hypertension.
Topics: Adolescent; Angiotensin II; Blood Pressure; Child; Diastole; Endothelin-1; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Nephrectomy; Postoperative Period; Renal Dialysis; Systole | 2001 |
Effects of angiotensin II and the AT(1) receptor antagonist losartan on the renal excretion of urodilatin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Endothelin-1; Glomerular Filtration Rate; Kidney; Losartan; Male; Peptide Fragments; Perfusion; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Sodium; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Load versus humoral activation in the genesis of early hypertensive heart disease.
Topics: Angiotensin II; Animals; Catecholamines; Diastole; Disease Models, Animal; Dogs; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Kidney; Natriuretic Peptide, Brain; Propranolol; Renin; Systole; Ventricular Dysfunction, Left | 2001 |
Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cells, Cultured; Endothelin-1; Gene Expression Regulation, Enzymologic; Isoproterenol; Matrix Metalloproteinases; Myocardial Contraction; Swine; Ventricular Function | 2001 |
Evidence for the involvement of nitric oxide in the control of steroid secretion by the frog adrenal gland.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Anura; Cells, Cultured; Corticosterone; Drug Interactions; Endothelin-1; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Nitroprusside; Steroids | 2001 |
Production and localisation of angiotensin II in the bovine early corpus luteum: a possible interaction with luteal angiogenic factors and prostaglandin F2 alpha.
Topics: Angiotensin II; Animals; Capillaries; Cattle; Corpus Luteum; Corpus Luteum Maintenance; Dinoprost; Endothelial Growth Factors; Endothelin-1; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Immunohistochemistry; Lymphokines; Microdialysis; Oxytocin; Peptidyl-Dipeptidase A; Pregnancy; Progesterone; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Disease Progression; Endothelin-1; Endothelins; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Male; Organ Size; Peptidyl-Dipeptidase A; Protein Precursors; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Survival Analysis; Thiazepines; Time Factors | 2001 |
Antihypertensive effects of D-polymannuronic sulfate and its related mechanisms in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelin-1; Heart Rate; Hexuronic Acids; Hypertension, Renovascular; Male; Nitric Oxide; Phaeophyceae; Rats; Rats, Inbred WKY | 2000 |
Angiotensin II and atrial natriuretic peptide in the cow oviductal contraction in vitro: direct effect and local secretion of prostaglandins, endothelin-1, and angiotensin II.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cattle; Dinoprost; Dinoprostone; Endothelin-1; Fallopian Tubes; Female; Follicular Phase; In Vitro Techniques; Luteal Phase; Microdialysis; Muscle Contraction; Muscle, Smooth; Ovulation; Prostaglandins | 2001 |
Up-regulation of parathyroid hormone-related protein in folic acid-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Cell Division; Disease Models, Animal; Endothelin-1; Endothelins; Epithelial Cells; Folic Acid; Immunohistochemistry; Kidney Cortex; Kidney Tubules; Male; Parathyroid Hormone-Related Protein; Peptidyl-Dipeptidase A; Protein Precursors; Proteins; Rats; Rats, Wistar; Regeneration; Up-Regulation | 2001 |
Antioxidants block angiotensin II-induced increases in blood pressure and endothelin.
Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Cyclic N-Oxides; Endothelin-1; Endothelins; Glomerular Filtration Rate; Kidney; Male; Nitrites; Prostaglandins; Rats; Rats, Sprague-Dawley; Renal Circulation; Renal Veins; Spin Labels; Thiobarbituric Acid Reactive Substances; Vitamin E | 2001 |
Vascular responses to endothelin-1, angiotensin-II, and U46619 in glycerol-induced acute renal failure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Angiotensin II; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Glycerol; In Vitro Techniques; Male; Perfusion; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Transient involvement of endothelin in hypertrophic remodeling of small arteries.
Topics: Angiotensin II; Animals; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hypertrophy; Mesenteric Arteries; Norepinephrine; Phenylpropionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance | 2001 |
Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Bosentan; Cardiac Output; Desoxycorticosterone; Endothelin-1; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Vascular Resistance; Vasoconstrictor Agents | 2001 |
Chronic effects of endothelin 1 and angiotensin II on gap junctions and intercellular communication in cardiac cells.
Topics: Angiotensin II; Animals; Animals, Newborn; Cell Communication; Cells, Cultured; Connexin 43; Connexins; Endothelin-1; Gap Junction alpha-5 Protein; Gap Junctions; Heart; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Biological; Myocardium; Rats; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptors, Angiotensin; Receptors, Endothelin; Up-Regulation | 2002 |
The vasoconstrictor response of uterine and mesenteric resistance arteries is differentially altered in the course of pregnancy.
Topics: Angiotensin II; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Endothelin-1; Female; Gestational Age; Mesentery; Phenylephrine; Pregnancy; Rats; Rats, Sprague-Dawley; Uterus; Vasoconstriction | 2001 |
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aorta; Blotting, Western; Cell Line; Endothelin-1; Gene Expression Regulation, Enzymologic; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Rats; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Angiotensin II activates collagen type I gene in the renal cortex and aorta of transgenic mice through interaction with endothelin and TGF-beta.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Pressure; Collagen Type I; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Gene Expression Regulation; Kidney Cortex; Male; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Transcriptional Activation; Transforming Growth Factor beta | 2001 |
Bradykinin and angiotensin II-induced [Ca2+]i rise in cultured rat pituitary folliculo-stellate cells.
Topics: Angiotensin II; Animals; Bradykinin; Caffeine; Calcium; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Estrenes; Galanin; Male; Neuropeptides; Neurotensin; Phosphodiesterase Inhibitors; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Pyrrolidinones; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Type C Phospholipases; Vasoconstrictor Agents | 2001 |
High glucose-enhanced activation of mesangial cell p38 MAPK by ET-1, ANG II, and platelet-derived growth factor.
Topics: Angiotensin II; Animals; Apoptosis; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Glomerular Mesangium; Glucose; Male; Mitogen-Activated Protein Kinases; Osmolar Concentration; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley | 2002 |
Intraluteal release of angiotensin II and progesterone in vivo during corpora lutea development in the cow: effect of vasoactive peptides.
Topics: Angiotensin II; Animals; Ants; Cattle; Corpus Luteum; Endothelin-1; Endothelium, Vascular; Female; Microdialysis; Progesterone; Receptors, Atrial Natriuretic Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Effects of adrenomedullin on hypertrophic responses induced by angiotensin II, endothelin-1 and phenylephrine.
Topics: Adrenomedullin; Angiotensin II; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cyclic AMP; Cyclic GMP; Drug Interactions; Endothelin-1; Gene Expression; Heart; Heart Ventricles; In Vitro Techniques; Myocardium; Natriuretic Peptide, Brain; Peptides; Phenylephrine; Rats; Sarcomeres | 2001 |
Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: involvement of autocrine/paracrine pathways.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autocrine Communication; Benzimidazoles; Biphenyl Compounds; Bosentan; Catheterization; DNA-Binding Proteins; Endothelin Receptor Antagonists; Endothelin-1; GATA4 Transcription Factor; In Vitro Techniques; Male; Myocardium; Paracrine Communication; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides; Tetrazoles; Transcription Factor AP-1; Transcription Factors; Ventricular Function | 2002 |
Positive inotropic effect of alpha 1-adrenoceptor stimulation in dog ventricular myocardium.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Angiotensin II; Animals; Cardiotonic Agents; Dogs; Endothelin-1; Female; Heart Ventricles; Male; Myocardial Contraction; Myocardium; Phenylephrine; Receptors, Adrenergic, alpha-1; Ventricular Function | 2001 |
Dendroaspis natriuretic peptide-like immunoreactivity and its regulation in rat aortic vascular smooth muscle.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Aorta; Carotid Arteries; Cell Division; Cells, Cultured; DNA; Elapid Venoms; Elapidae; Endothelin-1; Endothelium, Vascular; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Tubules; Male; Microscopy, Fluorescence; Molecular Sequence Data; Muscle, Smooth; Nitroprusside; Peptides; Protein Binding; Radioimmunoassay; Rats; Rats, Wistar; Time Factors; Transforming Growth Factor beta | 2002 |
Apoptosis signal-regulating kinase/nuclear factor-kappaB: a novel signaling pathway regulates cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cytokines; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; NF-kappa B; Phenylephrine; Reactive Oxygen Species; Signal Transduction | 2002 |
Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Size; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Heterotrimeric GTP-Binding Proteins; I-kappa B Proteins; Kinetics; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mutation; Myocardium; NF-kappa B; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Cell Surface; Sarcomeres | 2002 |
Effects of human urotensin II in isolated vessels of various species; comparison with other vasoactive agents.
Topics: Angiotensin II; Animals; Blood Vessels; Dose-Response Relationship, Drug; Endothelin-1; Guinea Pigs; Humans; In Vitro Techniques; Norepinephrine; Rabbits; Rats; Receptor, Endothelin A; Receptors, Cell Surface; Receptors, Endothelin; Receptors, G-Protein-Coupled; Species Specificity; Swine; Urotensins; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Activation of the cardiac endothelin system in left ventricular hypertrophy before onset of heart failure in TG(mREN2)27 rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Aspartic Acid Endopeptidases; Collagen; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Male; Metalloendopeptidases; Models, Animal; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Preproendothelin-1 gene polymorphism is related to a change in vascular reactivity in the human mammary artery in vitro.
Topics: Acetylcholine; Aged; Angiotensin II; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Endothelins; Female; Genotype; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Nitroprusside; Phenylephrine; Polymorphism, Genetic; Protein Precursors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Negative inotropic effects of angiotensin II, endothelin-1 and phenylephrine in indo-1 loaded adult mouse ventricular myocytes.
Topics: Alkaloids; Angiotensin II; Animals; Benzophenanthridines; Calcium; Depression, Chemical; Endothelin-1; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; Phenanthridines; Phenylephrine; Protein Kinase C | 2002 |
Neurohormonal activation does not explain elevated tissue factor expression in heart failure.
Topics: Adult; Aged; Angiotensin II; Endothelin-1; Female; Gene Expression Regulation; Heart Failure; Humans; Male; Middle Aged; Monocytes; Norepinephrine; Thromboplastin | 2002 |
Decoy oligonucleotide characterization of GATA-4 transcription factor in hypertrophic agonist induced responses of cardiac myocytes.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Binding Sites; Cardiomegaly; DNA-Binding Proteins; Endothelin-1; GATA4 Transcription Factor; Gene Expression Regulation; Myocardium; Natriuretic Peptide, Brain; Oligodeoxyribonucleotides; Phenylephrine; Promoter Regions, Genetic; Protein Binding; Rats; Transcription Factors | 2002 |
Nitric oxide inhibits the expression of proto-oncogene c-fos induced by angiotensin II and endothelin-1 in cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Cells, Cultured; Endothelin-1; Gene Expression Regulation; Genes, fos; Myocytes, Cardiac; Nitric Oxide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 2000 |
[The influence of nasal continual positive airway pressure on some vasoactive substances in patients with obstructive sleep apnea syndrome].
Topics: Angiotensin II; Cyclic AMP; Cyclic GMP; Endothelin-1; Positive-Pressure Respiration; Renin; Sleep Apnea, Obstructive; Thromboxane B2 | 2002 |
Aortic blood flow subtraction: an alternative method for measuring total renal blood flow in conscious dogs.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Abdominal; Arterial Occlusive Diseases; Benzimidazoles; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Dogs; Endothelin-1; Female; Homeostasis; Regional Blood Flow; Renal Artery; Renal Circulation; Reproducibility of Results; Rheology; Subtraction Technique; Tetrazoles; Ultrasonography; Vascular Resistance; Vasoconstrictor Agents | 2002 |
Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bosentan; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Humans; In Vitro Techniques; Middle Aged; Nitroprusside; Peptides, Cyclic; Saphenous Vein; Sulfonamides; Vasoconstriction; Vasodilation; Vasodilator Agents | 2002 |
Modulation of ANP-C receptor signaling by endothelin-1 in A-10 smooth muscle cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Atrial Natriuretic Factor; Cell Line; Colforsin; Down-Regulation; Endothelin-1; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Guanylate Cyclase; Kinetics; Muscle, Smooth, Vascular; Oxotremorine; Peptide Fragments; Rats; Receptors, Atrial Natriuretic Factor; Signal Transduction; Sodium Fluoride | 2002 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2002 |
Involvement of p44/42 mitogen-activated protein kinases in regulating angiotensin II- and endothelin-1-induced contraction of rat thoracic aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Endothelin-1; Enzyme Inhibitors; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Inbred F344; Vasoconstriction | 2002 |
Tempol selectively attenuates angiotensin II evoked vasoconstrictor responses in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Luminescent Measurements; Male; Mesenteric Arteries; Models, Cardiovascular; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Spin Labels; Superoxides; Vasoconstriction | 2002 |
Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation.
Topics: Adrenergic alpha-Antagonists; Adult; Alleles; Angiotensin II; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Heterotrimeric GTP-Binding Proteins; Heterozygote; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Nitric Oxide Synthase; Norepinephrine; Oligopeptides; omega-N-Methylarginine; Peptides, Cyclic; Piperidines; Protein Subunits; Skin; Vasoconstriction; Vasoconstrictor Agents; Yohimbine | 2002 |
Stretch-induced paracrine hypertrophic stimuli increase TGF-beta1 expression in cardiomyocytes.
Topics: Angiotensin II; Animals; Blotting, Northern; Cells, Cultured; Endothelin-1; Fibroblasts; Hypertrophy; Male; Muscle, Smooth; Myocardium; Paracrine Communication; Rats; Rats, Wistar; RNA; RNA, Messenger; Stress, Mechanical; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Chronic elevated endothelin-1 concentrations regulate mitogen-activated protein kinases ERK 1 and ERK 2 in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Benzhydryl Compounds; Cell Line; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pyrimidines; Rats; Receptor, Endothelin A | 2002 |
Haemodynamic and hormonal changes during haemorrhage in conscious dogs treated with an endothelin-A receptor antagonist.
Topics: Action Potentials; Acute Disease; Angiotensin II; Animals; Atrasentan; Blood Pressure; Cardiac Output; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Hemorrhage; Norepinephrine; Pyrrolidines; Random Allocation; Receptor, Endothelin A; Vascular Resistance; Vasodilator Agents; Vasopressins | 2002 |
Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Myocardium; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Precursors; Receptor, Bradykinin B2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Endothelin; RNA, Messenger; Sodium Chloride, Dietary | 2002 |
Effect of castration on endothelin receptors.
Topics: Angiotensin II; Animals; Brain; Dogs; Endothelin-1; Endothelin-3; Endothelins; Male; Orchiectomy; Prostate; Prostatic Neoplasms; Protein Binding; Receptors, Endothelin | 2002 |
Cyr61 and CTGF are molecular markers of bladder wall remodeling after outlet obstruction.
Topics: Angiotensin II; Animals; Biomarkers; Connective Tissue Growth Factor; Cysteine-Rich Protein 61; Endothelin-1; Gene Expression; Growth Substances; Hypertrophy; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Parathyroid Hormone-Related Protein; Proteins; Rats; Rats, Sprague-Dawley; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction; Vasoconstrictor Agents | 2002 |
Proliferative effects of angiotensin II and endothelin-1 on guinea pig gingival fibroblast cells in culture.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelin-1; Fibroblasts; Gingiva; Guinea Pigs; Male | 2002 |
Lysophosphatidylcholine potentiates the mitogenic effect of various vasoactive compounds on rabbit aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Arteriosclerosis; Cells, Cultured; DNA; Drug Synergism; Endothelin-1; Hydrogen Peroxide; Lysophosphatidylcholines; Mitogens; Muscle, Smooth, Vascular; Rabbits; Serotonin; Thromboxane A2; Thymidine; Type C Phospholipases; Urotensins; Vasoconstrictor Agents | 2002 |
Parathyroid hormone-related protein is produced in the myocardium and increased in patients with congestive heart failure.
Topics: Adult; Angiotensin II; Aorta; Atrial Natriuretic Factor; Coronary Vessels; Diastole; Echocardiography; Endothelin-1; Female; Heart Failure; Hemodynamics; Humans; Male; Myocardium; Natriuretic Peptide, Brain; Norepinephrine; Parathyroid Hormone-Related Protein; Peptide Fragments; Protein Biosynthesis; Proteins; Stroke Volume; Systole; Ventricular Function, Left | 2002 |
A functional activating protein 1 (AP-1) site regulates matrix metalloproteinase 2 (MMP-2) transcription by cardiac cells through interactions with JunB-Fra1 and JunB-FosB heterodimers.
Topics: Angiotensin II; Animals; Binding Sites; Cell Hypoxia; Cells, Cultured; Dimerization; Endothelin-1; Fibroblasts; Interleukin-1; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mutagenesis, Site-Directed; Myocytes, Cardiac; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Transcription, Genetic | 2003 |
Seasonal variation of endothelin-1, angiotensin II, and plasma catecholamines and their relation to outside temperature.
Topics: Adult; Angiotensin II; Climate; Endothelin-1; Epinephrine; Germany; Humans; Humidity; Longitudinal Studies; Middle Aged; Norepinephrine; Periodicity; Seasons; Temperature | 2002 |
Role of endothelin-1 and thromboxane A2 in renal vasoconstriction induced by angiotensin II in diabetes and hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Oligopeptides; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Thromboxane A2; Vascular Resistance; Vasoconstriction | 2002 |
Release of preformed Ang II from myocytes mediates angiotensinogen and ET-1 gene overexpression in vivo via AT1 receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aortic Valve Stenosis; Cardiac Catheterization; Cytoplasm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart; Insulin-Like Growth Factor I; Microscopy, Confocal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stress, Mechanical; Swine; Systole; Tetrazoles; Valine; Valsartan | 2002 |
Role of thromboxane, catecholamines and endothelin-1 in the renal constrictor response to angiotensin II in diabetic hypertensive rats.
Topics: Angiotensin II; Animals; Blood Glucose; Blood Pressure; Body Weight; Catecholamines; Diabetes Mellitus, Experimental; Endothelin-1; Hypertension, Renal; In Vitro Techniques; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Thromboxanes; Vasoconstrictor Agents | 2002 |
Effects of tetrandrine on smooth muscle contraction induced by mediators in pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alkaloids; Angiotensin II; Animals; Antihypertensive Agents; Benzylisoquinolines; Endothelin-1; Guinea Pigs; Hypertension, Pulmonary; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neuropeptide Y; Pulmonary Artery; Rats; Rats, Sprague-Dawley; SRS-A | 2002 |
Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aorta; Aspartic Acid Endopeptidases; Disease Models, Animal; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Extracellular Matrix; Fibroblast Growth Factor 2; Fibronectins; Heart Diseases; Heart Ventricles; Humans; Immunohistochemistry; Kidney; Male; Metalloendopeptidases; Prodrugs; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 2002 |
Gender difference in vascular and platelet reactivity to thromboxane A(2)-mimetic U46619 and to endothelial dependent vasodilation in Zucker fatty (hypertensive, hyperinsulinemic) diabetic rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Type 2; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Female; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Platelet Aggregation; Rats; Rats, Zucker; Renal Circulation; Sex Characteristics; Vasoconstrictor Agents; Vasodilation | 2003 |
Ca2+ mobilization in saphenous vein smooth muscle cells derived from patients with primary varicosity.
Topics: Adult; Angiotensin II; Bradykinin; Calcium; Calcium Signaling; Case-Control Studies; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Endothelin-1; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Saphenous Vein; Thrombin; Varicose Veins; Vasoconstrictor Agents | 2002 |
Role of K+ATP channels, endothelin A receptors, and effect of angiotensin II on blood flow in oral tissues.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Anti-Arrhythmia Agents; Dental Pulp; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Female; Ferrets; Gingiva; Glyburide; Laser-Doppler Flowmetry; Matched-Pair Analysis; Peptides, Cyclic; Potassium Channel Blockers; Potassium Channels; Receptor, Endothelin A; Receptors, Angiotensin; Receptors, Endothelin; Regional Blood Flow; Statistics, Nonparametric; Vasodilation; Vasodilator Agents | 2003 |
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles | 2003 |
Pericyte-specific expression of Rgs5: implications for PDGF and EDG receptor signaling during vascular maturation.
Topics: 3T3 Cells; Angiotensin II; Animals; Arteries; Endothelin-1; Immediate-Early Proteins; In Situ Hybridization; Lysophospholipids; Mice; Mitogen-Activated Protein Kinase 1; Models, Biological; Pericytes; Phosphorylation; Platelet-Derived Growth Factor; Receptor, Platelet-Derived Growth Factor beta; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Receptors, Platelet-Derived Growth Factor; RGS Proteins; RNA, Messenger; Signal Transduction; Sphingosine; Transcription, Genetic | 2003 |
Cysteinyl leukotriene-dependent [Ca2+]i responses to angiotensin II in cardiomyocytes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Arginine Vasopressin; Benzoquinones; Calcium; Cysteine; Endothelin-1; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart; Imidazoles; Inositol 1,4,5-Trisphosphate; Leukotriene C4; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Losartan; Myocardium; Propionates; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Spectrometry, Fluorescence | 2003 |
[Changes of ultrastructure and function of the aortic endothelium in streptozotocin-diabetic rats and effect of perindopril].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelin-1; Endothelium, Vascular; Male; Perindopril; Random Allocation; Rats; Rats, Sprague-Dawley | 2001 |
Contribution of endogenous endothelin in the enhanced coronary constriction in DOCA-salt hypertensive rats.
Topics: Angiotensin II; Animals; Coronary Circulation; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Heart; Hypertension; In Vitro Techniques; Male; Nephrectomy; Oligopeptides; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2003 |
The aorta and heart differentially express RGS (regulators of G-protein signalling) proteins that selectively regulate sphingosine 1-phosphate, angiotensin II and endothelin-1 signalling.
Topics: Angiotensin II; Aorta; Base Sequence; Blotting, Northern; Cell Line; DNA Primers; Endothelin-1; Humans; Lysophospholipids; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RGS Proteins; RNA, Messenger; Signal Transduction; Sphingosine | 2003 |
Endothelin-1 and vasopressin plasma levels are not associated with the insertion/deletion polymorphism of the human angiotensin I-converting enzyme gene in patients with coronary artery disease.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Coronary Artery Disease; Endothelin-1; Female; Gene Deletion; Humans; Male; Middle Aged; Mutagenesis, Insertional; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin; Vasoconstrictor Agents; Vasopressins | 2003 |
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents | 2003 |
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Hypertension; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Muscle Proteins; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; NG-Nitroarginine Methyl Ester; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Threonine | 2003 |
Role of cyclooxygenase 2, p38 and p42/44 MAPK in the secretion of prostacyclin induced by epidermal growth factor, endothelin-1 and angiotensin II in rat ventricular cardiomyocytes.
Topics: Angiotensin II; Animals; Cyclooxygenase 2; Endothelin-1; Epidermal Growth Factor; Epoprostenol; Isoenzymes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Rats | 2003 |
The expression of angiotensin and endothelin system members in bovine corpus luteum during estrous cycle and pregnancy.
Topics: Angiotensin II; Angiotensins; Animals; Aspartic Acid Endopeptidases; Cattle; Corpus Luteum; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Estrous Cycle; Female; Luteal Phase; Luteolysis; Metalloendopeptidases; Peptidyl-Dipeptidase A; Pregnancy; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Angiotensin; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Endothelin ETA receptor antagonism does not attenuate angiotensin II-induced cardiac hypertrophy in vivo in rats.
Topics: Aldosterone; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Cardiomegaly; Endothelin A Receptor Antagonists; Endothelin-1; Heart Ventricles; Infusions, Intravenous; Male; Oxazoles; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides | 2003 |
Endothelin-1 directly modulates its own secretion: studies utilising the cell immunoblot technique.
Topics: Angiotensin II; Bosentan; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Humans; Immunoblotting; Oligopeptides; Piperidines; Sulfonamides | 2003 |
Sex differences in the modulation of K+ currents in diabetic rat cardiac myocytes.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Electric Stimulation; Endothelin-1; Estradiol; Estrogen Replacement Therapy; Female; In Vitro Techniques; Male; Membrane Potentials; Myocytes, Cardiac; Ovariectomy; Patch-Clamp Techniques; Potassium Channels; Quinapril; Rats; Rats, Sprague-Dawley; Sex Characteristics; Tetrahydroisoquinolines | 2003 |
Tumor necrosis factor alpha in the bovine oviduct during the estrous cycle: messenger RNA expression and effect on secretion of prostaglandins, endothelin-1, and angiotensin II.
Topics: Angiotensin II; Animals; Antigens, CD; Cattle; Dinoprost; Dinoprostone; Endothelin-1; Estrous Cycle; Fallopian Tubes; Female; Gene Expression Regulation; In Vitro Techniques; Microdialysis; Prostaglandins; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Increased endogenous endothelin-1 in coronary circulation is associated with restenosis after coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Angiotensin II; Biomarkers; Coronary Angiography; Coronary Circulation; Coronary Restenosis; Endothelin-1; Female; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Norepinephrine; Risk Factors; Serotonin; Statistics as Topic; Vascular Patency | 2003 |
Effects of certain vasoactive peptides on pathogenesis of vascular restenosis.
Topics: Adrenomedullin; Angioplasty, Balloon; Angiotensin II; Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Cell Division; Cells, Cultured; Coronary Restenosis; Endothelin-1; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Vasodilator Agents | 2003 |
Cholesterol dependence of vascular ERK1/2 activation and growth in response to stretch: role of endothelin-1.
Topics: Angiotensin II; Animals; Caveolae; Caveolin 1; Caveolins; Cholesterol; Endothelin-1; Enzyme Activation; Female; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Organ Culture Techniques; Peptide Biosynthesis; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Subcellular Fractions | 2003 |
Phenoxybenzamine treatment is insufficient to prevent spasm in the radial artery: the effect of other vasodilators.
Topics: Adrenergic alpha-Agonists; Aged; Angiotensin II; Coronary Artery Bypass; Diltiazem; Dose-Response Relationship, Drug; Endothelin-1; Humans; Middle Aged; Nitroglycerin; Norepinephrine; Papaverine; Peripheral Vascular Diseases; Phenoxybenzamine; Phosphodiesterase Inhibitors; Radial Artery; Spasm; Time Factors; Treatment Outcome; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2003 |
Inhibition of prostaglandin synthesis does not affect contractile responses to noradrenaline, serotonin, angiotensin II nor endothelin-1 in human forearm isolated veins.
Topics: Adult; Aged; Angiotensin II; Endothelin-1; Forearm; Humans; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandin Antagonists; Prostaglandins; Serotonin; Vasoconstrictor Agents; Veins | 1993 |
Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Calcium Channels, T-Type; Cells, Cultured; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Heart Ventricles; Male; Myocytes, Cardiac; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sulfonamides | 2003 |
Endothelin-1 concentrations in pericardial fluid are more elevated in patients with ischemic heart disease than in patients with nonischemic heart disease.
Topics: Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Growth Substances; Humans; Myocardial Ischemia; Myocardium; Natriuretic Peptide, Brain; Pericardial Effusion; Prognosis; Receptors, Tumor Necrosis Factor | 2003 |
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; Calcium Channels, T-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Constriction, Pathologic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Gene Expression; Losartan; Male; Membrane Potentials; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nickel; Nitriles; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Sulfonamides | 2003 |
Different growth factor activation in the right and left ventricles in experimental volume overload.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Cardiac Volume; Collagen; Endothelin-1; Female; Growth Substances; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Hypertrophy, Right Ventricular; Insulin-Like Growth Factor I; Male; RNA, Messenger; Swine | 2004 |
Involvement of reactive oxygen species in angiotensin II-induced endothelin-1 gene expression in rat cardiac fibroblasts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azepines; Cell Culture Techniques; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Fibroblasts; Gene Expression; Heart; Losartan; Mitogen-Activated Protein Kinases; Oligopeptides; Oxidation-Reduction; Rats; Reactive Oxygen Species; Receptors, Angiotensin; Receptors, Endothelin; Signal Transduction; Up-Regulation | 2003 |
Cardiac hypertrophy in aryl hydrocarbon receptor null mice is correlated with elevated angiotensin II, endothelin-1, and mean arterial blood pressure.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomarkers; Captopril; Disease Models, Animal; Echocardiography; Endothelin-1; Genetic Markers; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptors, Aryl Hydrocarbon; RNA, Messenger; Ventricular Myosins | 2003 |
Superoxide does not mediate the acute vasoconstrictor effects of angiotensin II: a study in human and porcine arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetophenones; Adolescent; Adult; Angiotensin II; Animals; Catecholamines; Child; Child, Preschool; Coronary Vessels; Cyclic N-Oxides; Dopamine Agonists; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Female; Femoral Artery; Free Radical Scavengers; Humans; Imidazolines; Male; Myocardial Contraction; NAD; NADP; Nitroprusside; Oxidants; S-Nitroso-N-Acetylpenicillamine; Spin Labels; Superoxide Dismutase; Superoxides; Swine; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthine Oxidase | 2003 |
A low dose of angiotensin II increases inotropism through activation of reverse Na(+)/Ca(2+) exchange by endothelin release.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cats; Electrophysiology; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glycopeptides; Guanidines; In Vitro Techniques; Losartan; Muscle Contraction; Papillary Muscles; Patch-Clamp Techniques; Peptides, Cyclic; Sodium-Calcium Exchanger; Sulfones; Thiourea | 2003 |
5-hydroxytryptamine and thromboxane A2 as physiologic mediators of human umbilical artery closure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Bradykinin; Endothelin-1; Female; Histamine; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Phenylephrine; Pregnancy; Serotonin; Thromboxane A2; Umbilical Arteries; Vasoconstriction; Vasoconstrictor Agents | 2003 |
Relative roles of endothelin-1 and angiotensin II in experimental post-ischaemic acute renal failure.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Infusions, Intravenous; Kidney; Losartan; Male; Models, Animal; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides | 2004 |
Angiotensin II induces endothelin-1 gene expression via extracellular signal-regulated kinase pathway in rat aortic smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Aorta; Azepines; Binding Sites; Butadienes; Cells, Cultured; Endothelin A Receptor Antagonists; Endothelin-1; Gene Expression; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nitriles; Oligopeptides; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Transcription Factor AP-1 | 2004 |
Stimulation of NHE3 in OKP cells by an autocrine mechanism.
Topics: Acidosis; Amiloride; Angiotensin II; Animals; Autocrine Communication; Benzoquinones; Cell Line; Culture Media, Conditioned; Dose-Response Relationship, Drug; Endothelin B Receptor Antagonists; Endothelin-1; Hydrogen-Ion Concentration; Kidney; Lactams, Macrocyclic; Oligopeptides; Opossums; Piperidines; Potassium; Protein-Tyrosine Kinases; Quinones; Receptor, Endothelin B; Rifabutin; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Time Factors | 2004 |
Obligatory role for endogenous endothelin in mediating the hypertrophic effects of phenylephrine and angiotensin II in neonatal rat ventricular myocytes: evidence for two distinct mechanisms for endothelin regulation.
Topics: Angiotensin II; Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Gene Expression; Heart Ventricles; Hypertrophy; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Muscle Cells; Myocardium; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 2004 |
Cardiac remodeling: is 8 the heart's lucky number?
Topics: Angiotensin II; Animals; Chick Embryo; Endothelin-1; Heart; Humans; Integrin alpha Chains; Integrin beta Chains; MAP Kinase Kinase Kinases; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardium; Myocytes, Cardiac; Signal Transduction | 2004 |
Effect of angiotensin II and endothelin-1 receptor blockade on the haemodynamic and hormonal changes after acute blood loss and after retransfusion in conscious dogs.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Blood Transfusion; Cardiac Output; Dogs; Endothelin-1; Epinephrine; Female; Glomerular Filtration Rate; Hemodynamics; Hemorrhage; Losartan; Norepinephrine; Pyrrolidines; Receptor, Endothelin A; Stroke Volume; Urine; Vascular Resistance; Vasopressins | 2004 |
[The preliminary studies on the cross action between endothelin-1 and angiotensin II in kidney tissue of rats with diabetic nephropathy].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Endothelin-1; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; RNA, Messenger | 2004 |
Activation of IP prostanoid receptors prevents cardiomyocyte hypertrophy via cAMP-dependent signaling.
Topics: Angiotensin II; Animals; Biomarkers; Cardiomegaly; Cyclic AMP; Endothelin-1; Epoprostenol; Iloprost; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Receptors, Epoprostenol; Receptors, Prostaglandin; Signal Transduction | 2004 |
Enhanced contractility of renal afferent arterioles from angiotensin-infused rabbits: roles of oxidative stress, thromboxane prostanoid receptors, and endothelium.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8,11,14-Eicosatrienoic Acid; Angiotensin II; Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Cyclic N-Oxides; Cyclooxygenase 2; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Endothelium, Vascular; Isoenzymes; Kidney; Male; Nitroarginine; Norepinephrine; Oxazoles; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Receptors, Thromboxane; RNA, Messenger; Spin Labels; Superoxides; Vascular Resistance; Vasoconstriction | 2004 |
Angiotensin II and endothelin-1 regulate MAP kinases through different redox-dependent mechanisms in human vascular smooth muscle cells.
Topics: Angiotensin II; Blotting, Western; Endothelin-1; Humans; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidation-Reduction; Reactive Oxygen Species | 2004 |
Selective vasodilator effect of magnesium sulfate in human placenta.
Topics: Angiotensin II; Endothelin-1; Female; Humans; Interleukin-1; Magnesium Sulfate; Placenta; Pregnancy; Substrate Specificity; Thromboxanes; Vasodilation; Vasodilator Agents | 2004 |
Acetazolamide prevents hypoxic pulmonary vasoconstriction in conscious dogs.
Topics: Acetazolamide; Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cardiac Output; Consciousness; Dogs; Endothelin-1; Female; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Oxygen; Potassium; Pulmonary Circulation; Renin; Respiratory Mechanics; Sodium; Vasoconstriction | 2004 |
Real-time relationships in intraluteal release among Prostaglandin F2alpha, endothelin-1, and angiotensin II during spontaneous luteolysis in the cow.
Topics: Angiotensin II; Animals; Cattle; Corpus Luteum; Dinoprost; Endothelin-1; Female; Luteolysis; Microdialysis; Osmolar Concentration; Progesterone; Time Factors | 2004 |
In-vitro contraction of the equine aortic valve.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Aortic Valve; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Endothelin-1; Fatty Acids, Unsaturated; Free Radical Scavengers; Horses; Hydrazines; Medetomidine; Models, Animal; Models, Cardiovascular; Myocardial Contraction; Norepinephrine; Phenylephrine; Prostaglandin Endoperoxides, Synthetic; Receptors, Thromboxane; Serotonin; Statistics as Topic; Vasoconstrictor Agents | 2004 |
Endothelin-B-receptor-selective antagonist inhibits endothelin-1 induced potentiation on the vasoconstriction to noradrenaline and angiotensin II.
Topics: Adult; Angiotensin II; Dose-Response Relationship, Drug; Drug Synergism; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Norepinephrine; Oligopeptides; Peptides, Cyclic; Piperidines; Skin; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats.
Topics: Acetylcholine; Amides; Angiotensin II; Animals; Blotting, Western; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Lipopolysaccharides; Mesenteric Arteries; Nitrates; Nitrites; Phenylephrine; Potassium Chloride; Protein Serine-Threonine Kinases; Pyridines; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; Sodium Chloride; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2004 |
Signaling molecules in overcirculation-induced pulmonary hypertension in piglets: effects of sildenafil therapy.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Anastomosis, Surgical; Angiopoietin-1; Angiotensin II; Animals; Arterioles; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Protein Receptors, Type II; Cyclic Nucleotide Phosphodiesterases, Type 5; Drug Evaluation, Preclinical; Endothelin-1; Gene Expression Regulation; Hyperplasia; Hypertension, Pulmonary; Models, Animal; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Protein Serine-Threonine Kinases; Pulmonary Artery; Purines; Random Allocation; Receptors, Growth Factor; RNA, Messenger; Signal Transduction; Sildenafil Citrate; Subclavian Artery; Sulfones; Sus scrofa; Vascular Endothelial Growth Factor A | 2004 |
Differential inotropic effects of endothelin-1, angiotensin II, and phenylephrine induced by crosstalk with cAMP-mediated signaling process in dog ventricular myocardium.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cyclic AMP; Dogs; Endothelin-1; Female; GTP-Binding Protein alpha Subunits, Gq-G11; Heart Ventricles; Male; Myocardial Contraction; Myocardium; Phenylephrine; Signal Transduction; Stimulation, Chemical | 2004 |
Contractile responses of aortae from WKY and SHR to vasoconstrictors.
Topics: Age Factors; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Hypertension; In Vitro Techniques; Male; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Urotensins; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Sex-specific effects of dual ET-1/ANG II receptor (Dear) variants in Dahl salt-sensitive/resistant hypertension rat model.
Topics: Angiotensin II; Animals; Animals, Congenic; Base Sequence; Blood Pressure; Blotting, Western; Cell Membrane; Cohort Studies; Crosses, Genetic; DNA, Complementary; Endothelin-1; Female; Genetic Linkage; Genetic Predisposition to Disease; Genetic Variation; Hypertension; Kinetics; Ligands; Male; Molecular Sequence Data; Phenotype; Polymorphism, Single-Stranded Conformational; Protein Binding; Rats; Rats, Inbred Dahl; Salts; Sex Factors; Sodium Chloride; Sodium Chloride Symporters; Sodium Chloride, Dietary; Species Specificity | 2005 |
Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Cattle; Cells, Cultured; Drug Administration Schedule; Endothelin-1; Glomerular Filtration Rate; Hepatocyte Growth Factor; Kidney; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2005 |
AT-1 receptor antagonism modifies the mediation of endothelin-1, thromboxane A2, and catecholamines in the renal constrictor response to angiotensin II.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Catecholamines; Dose-Response Relationship, Drug; Endothelin-1; Irbesartan; Male; Potassium Chloride; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renal Circulation; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents | 2005 |
PKCepsilon-PKD1 signaling complex at Z-discs plays a pivotal role in the cardiac hypertrophy induced by G-protein coupling receptor agonists.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Endothelin-1; Heart; Mutation; Myocardium; Norepinephrine; Phorbol Esters; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction | 2005 |
Position of Src tyrosine kinases in the interaction between angiotensin II and endothelin in in vivo vascular protein synthesis.
Topics: Angiotensin II; Animals; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Biosynthesis; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; src-Family Kinases; Vascular Resistance | 2005 |
Enhanced angiotensin II-mediated effects in fibroblasts of patients with familial hypercholesterolemia.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis; Biphenyl Compounds; Calcium; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cholesterol, LDL; Dose-Response Relationship, Drug; Endothelin-1; Female; Fibroblasts; Heterozygote; Humans; Hyperlipoproteinemia Type II; Irbesartan; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Middle Aged; Receptor, Angiotensin, Type 1; Tetrazoles; Transforming Growth Factor beta | 2005 |
Crosstalk between mesangial and endothelial cells: angiotensin II down-regulates endothelin-converting enzyme 1.
Topics: Angiotensin II; Aspartic Acid Endopeptidases; Cell Communication; Cells, Cultured; Coculture Techniques; Down-Regulation; Endothelial Cells; Endothelin-1; Endothelin-Converting Enzymes; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Humans; Metalloendopeptidases; RNA, Messenger; Signal Transduction; Umbilical Veins | 2005 |
Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Aqueous Humor; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, G12-G13; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Myosin Light Chains; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Reverse Transcriptase Polymerase Chain Reaction; rho GTP-Binding Proteins; rho-Associated Kinases; Trabecular Meshwork | 2005 |
Endothelin mediates superoxide production in angiotensin II-induced hypertension in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; In Vitro Techniques; Male; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Peptides, Cyclic; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Superoxides | 2005 |
Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin II; Anilides; Animals; Aorta, Thoracic; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Genistein; Hypertension; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Phosphoproteins; PPAR gamma; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Signal Transduction; Stroke; Superoxides; Tyrosine; Vasoconstrictor Agents | 2004 |
Receptor-induced depletion of phosphatidylinositol 4,5-bisphosphate inhibits inwardly rectifying K+ channels in a receptor-specific manner.
Topics: Acetylcholine; Androstadienes; Angiotensin II; Animals; Bradykinin; Dinoprost; Endothelin-1; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GTP-Binding Protein alpha Subunits, Gq-G11; In Vitro Techniques; Mice; Myocytes, Cardiac; Naphthalenes; Patch-Clamp Techniques; Phenylephrine; Phosphatidylinositol 4,5-Diphosphate; Potassium Channels, Inwardly Rectifying; Wortmannin | 2005 |
[Influence of endothelin on local aldosterone production synthesized by human renal tubular cells].
Topics: Aldosterone; Angiotensin II; Cell Line; Dose-Response Relationship, Drug; Endothelin-1; Endothelium; Humans; Kidney Tubules, Proximal | 2005 |
Activation of calcineurin in human failing heart ventricle by endothelin-1, angiotensin II and urotensin II.
Topics: Adult; Angiotensin II; Blotting, Western; Calcineurin; Endothelin-1; Female; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Male; Middle Aged; Myocardial Contraction; Peptides; Phosphates; Protein Kinase C; Tacrolimus; Urotensins | 2005 |
Inhibition of angiotensin II induced endothelin-1 gene expression by 17-beta-oestradiol in rat cardiac fibroblasts.
Topics: Angiotensin II; Animals; Cell Communication; Cell Proliferation; Cells, Cultured; DNA; Endothelin-1; Estradiol; Fibroblasts; Gene Expression; Myocardium; NADPH Oxidases; Phosphorylation; Rats; Reactive Oxygen Species | 2005 |
CGS 35601 and its orally active prodrug CGS 37808 as triple inhibitors of endothelin-converting enzyme-1, neutral endopeptidase 24.11, and angiotensin-converting enzyme.
Topics: Administration, Oral; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; CHO Cells; Cricetinae; Cricetulus; Dipeptides; Endothelin-1; Endothelin-Converting Enzymes; Humans; Indoles; Injections, Intravenous; Male; Metalloendopeptidases; Neprilysin; Peptidyl-Dipeptidase A; Prodrugs; Protease Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Time Factors; Transfection | 2004 |
Endothelin-1 within the corpus luteum during spontaneous luteolysis in the cow: local interaction with prostaglandin F2alpha and angiotensin II.
Topics: Angiotensin II; Animals; Cattle; Corpus Luteum; Dinoprost; Endothelin-1; Feedback, Physiological; Female; Luteolysis; Microdialysis; Paracrine Communication; Progesterone; Time Factors | 2004 |
Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Aldosterone; Angiotensin II; Cell Line, Tumor; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Endothelin-2; Endothelin-3; Humans; Peptides, Cyclic; Receptor, Endothelin A; Receptor, Endothelin B; Serum; Up-Regulation | 2004 |
Endothelin-1 regulates protein kinase C isoforms differently in smooth muscle cells and in cardiomyocytes.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Line; Cytoplasm; Endothelin-1; Infusions, Parenteral; Isoenzymes; Male; Muscle, Smooth, Vascular; Myocytes, Cardiac; Myocytes, Smooth Muscle; Protein Kinase C-alpha; Protein Kinase C-delta; Protein Kinase C-epsilon; Rats; Time Factors; Up-Regulation | 2004 |
Effects of endothelin receptor antagonist on expression of AT1 and AT2 receptors in the heart of SHR-SP.
Topics: Angiotensin II; Animals; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Hypertension; Indans; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke | 2004 |
Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.
Topics: Angiotensin II; Animals; Carbachol; Cell Line; Diabetes Mellitus, Experimental; Endothelin-1; ErbB Receptors; Female; Genistein; Histamine; Humans; In Vitro Techniques; Mesenteric Arteries; Mesenteric Veins; Norepinephrine; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Streptozocin; Tyrphostins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Resveratrol inhibits angiotensin II-induced endothelin-1 gene expression and subsequent proliferation in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Binding Sites; Blotting, Northern; Blotting, Western; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Hydrogen Peroxide; Luciferases; Male; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Stilbenes; Transcription Factor AP-1; Transfection | 2005 |
Estrogen inhibits cardiomyocyte hypertrophy in vitro. Antagonism of calcineurin-related hypertrophy through induction of MCIP1.
Topics: Angiotensin II; Animals; Animals, Newborn; Calcineurin; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Endothelin-1; Estradiol; Estrogens; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Intracellular Signaling Peptides and Proteins; Leucine; Microscopy, Fluorescence; Models, Biological; Muscle Proteins; Myocytes, Cardiac; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rats; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Time Factors; Transcription, Genetic | 2005 |
Blood pressure variability, cardiac baroreflex sensitivity and organ damage in experimentally hypertensive rats.
Topics: Angiotensin II; Animals; Baroreflex; Blood Pressure; Blood Pressure Determination; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Hypertension; Hypertension, Renovascular; Interleukin-1; Kidney Glomerulus; Male; Myocardium; NG-Nitroarginine Methyl Ester; Organ Size; Rats; Rats, Sprague-Dawley; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
KATP channel conductance of descending vasa recta pericytes.
Topics: Angiotensin II; Animals; ATP-Binding Cassette Transporters; Electric Capacitance; Endothelin-1; Glyburide; Juxtaglomerular Apparatus; KATP Channels; Membrane Potentials; Pericytes; Pinacidil; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Vasopressins | 2005 |
A new ATP-sensitive potassium channel opener protects the kidney from hypertensive damage in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; ATP-Binding Cassette Transporters; Benzazepines; Endothelin-1; Extracellular Matrix; Hemodynamics; Hypertension; Immunohistochemistry; KATP Channels; Kidney; Kidney Diseases; Kidney Function Tests; Potassium Channels, Inwardly Rectifying; Propylamines; Rats; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Characterizing the role of endothelin-1 in the progression of cardiac hypertrophy in aryl hydrocarbon receptor (AhR) null mice.
Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Disease Progression; Echocardiography; Endothelin A Receptor Antagonists; Endothelin-1; Fibrosis; Hypertrophy, Left Ventricular; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Organ Size; Peptides, Cyclic; Receptor, Endothelin A; Receptors, Aryl Hydrocarbon; RNA, Messenger | 2006 |
Altered fibroblast function following myocardial infarction.
Topics: Angiotensin II; Animals; Autoantibodies; Cell Adhesion; Cell Movement; Cell Proliferation; Collagen; Discoidin Domain Receptors; Endothelin-1; Female; Fibroblasts; Heart Ventricles; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Endothelin-1 expression in vascular adventitial fibroblasts.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cells, Cultured; Cloning, Molecular; Collagen Type I; Connective Tissue; DNA, Complementary; Endothelin-1; Fibroblasts; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 2006 |
Leptin induces vascular smooth muscle cell hypertrophy through angiotensin II- and endothelin-1-dependent mechanisms and mediates stretch-induced hypertrophy.
Topics: Angiotensin II; Animals; Cell Culture Techniques; Cells, Cultured; Culture Media; Endothelin-1; Hypertrophy; Leptin; Male; Models, Biological; Muscle, Smooth, Vascular; Organ Size; Portal Vein; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Leptin; Stress, Mechanical; Up-Regulation | 2005 |
Tetramethylpyrazine downregulates angiotensin II-induced endothelin-1 gene expression in vascular endothelial cells.
Topics: Angiotensin II; Antioxidants; Blotting, Northern; Blotting, Western; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Down-Regulation; Endothelial Cells; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Humans; Phosphorylation; Promoter Regions, Genetic; Pyrazines; Reactive Oxygen Species; Recombinant Fusion Proteins; RNA, Messenger; Superoxides; Transfection | 2005 |
Angiotensin II sensitivity of afferent glomerular arterioles in endothelin-1 transgenic mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Gene Expression; In Vitro Techniques; Kidney Glomerulus; Male; Mice; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Polymerase Chain Reaction; Receptors, Angiotensin; Renal Artery; Renin; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents | 2005 |
Plasma levels of endothelin-1, angiotensin II, nitric oxide and prostaglandin E in the venous and cavernosal blood of patients with erectile dysfunction.
Topics: Adult; Angiotensin II; Case-Control Studies; Dinoprostone; Endothelin-1; Erectile Dysfunction; Humans; Male; Middle Aged; Nitric Oxide; Penis; Sexual Dysfunctions, Psychological; Vasodilation | 2005 |
Vasoconstrictive effect of angiotensin IV in isolated rat basilar artery independent of AT1 and AT2 receptors.
Topics: Angiotensin II; Animals; Basilar Artery; Drug Interactions; Endothelin-1; Endothelium, Vascular; Gene Expression; In Vitro Techniques; Male; Oligopeptides; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents | 2006 |
Interleukin-8 synthesis, regulation, and steroidogenic role in H295R human adrenocortical cells.
Topics: Adrenal Cortex; Aldosterone; Analysis of Variance; Angiotensin II; Cell Line; Cytokines; Endothelin-1; Humans; Hydrocortisone; Interleukin-8; Potassium; RNA, Messenger; Statistics, Nonparametric | 2006 |
[Study of effects of drugs on myocardial hypertrophy due to overload].
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Disease Models, Animal; Endothelin-1; Hypertrophy, Left Ventricular; Imidazolidines; Myocardium; Propanolamines; Random Allocation; Rats; Tumor Necrosis Factor-alpha | 2005 |
Inhibition of angiotensin II- and endothelin-1-stimulated proliferation by selective MEK inhibitor in cultured rabbit gingival fibroblastsdagger.
Topics: Angiotensin II; Animals; Blotting, Western; Butadienes; Cell Proliferation; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; MAP Kinase Kinase Kinases; Nitriles; Peptides, Cyclic; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Saralasin | 2005 |
Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Indoles; Male; Metalloendopeptidases; Neprilysin; Nitric Oxide; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species | 2005 |
Pathways of glomerular toxicity of cyclosporine-A: an "in vitro" study.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin-1; Female; Kidney Glomerulus; Oligopeptides; Organ Culture Techniques; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors | 2005 |
[The changes of some vasoactive substances after operation in patients with obstructive sleep apnea-hypopnea syndrome].
Topics: Angiotensin II; Antibodies, Antiphospholipid; Case-Control Studies; Chymosin; Endothelin-1; Humans; Sleep Apnea, Obstructive; Thromboxane B2 | 2005 |
Role of adiponectin receptors in endothelin-induced cellular hypertrophy in cultured cardiomyocytes and their expression in infarcted heart.
Topics: Adiponectin; Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Endothelin-1; Endothelins; Image Processing, Computer-Assisted; Immunohistochemistry; Myocardial Infarction; Myocytes, Cardiac; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adiponectin; Receptors, Cell Surface; RNA, Messenger; RNA, Small Interfering; Transfection; Tumor Necrosis Factor-alpha | 2006 |
Effects of trans-resveratrol on hypertension-induced cardiac hypertrophy using the partially nephrectomized rat model.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Cardiovascular Agents; Endothelin-1; Hypertension, Renal; Male; Myocardium; Nephrectomy; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
Antiproliferative effect of isosteviol on angiotensin-II-treated rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Endothelin-1; Male; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sweetening Agents | 2006 |
Increased vascular angiotensin II binding capacity and ET-1 release in young cardiomyopathic hamsters.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Binding, Competitive; Cardiomyopathies; Cricetinae; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; In Vitro Techniques; Losartan; Male; Mesocricetus; Peptides, Cyclic; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Vasoconstriction; Vasoconstrictor Agents | 2006 |
The positive inotropic effect of angiotensin II: role of endothelin-1 and reactive oxygen species.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cats; Endothelin-1; Immunohistochemistry; Myocardial Contraction; Myocytes, Cardiac; Reactive Oxygen Species; Receptor, Endothelin A; Sarcomeres; Sodium-Hydrogen Exchangers; Staining and Labeling | 2006 |
Angiotensin II effect on hydraulic permeability: interaction with endothelin-1, nitric oxide, and platelet activating factor.
Topics: Angiotensin II; Animals; Capillary Permeability; Drug Interactions; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Platelet Activating Factor; Rats; Rats, Sprague-Dawley | 2006 |
[Preventive effect of trans-resveratrol on hypertension-induced cardiac hypertrophy in partially nephrectomized rats].
Topics: Angiotensin II; Animals; Cardiomegaly; Cardiovascular Agents; Endothelin-1; Hypertension; Male; Myocardium; Nephrectomy; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2005 |
[In vitro effects of cAMP- and cGMP-stimulating drugs on the relaxation of the prostate smooth muscle tissue contraction induced by endothelin-1].
Topics: Adenylyl Cyclases; Aged; Angiotensin II; Colforsin; Cyclic AMP; Cyclic GMP; Endothelin-1; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitroprusside; Prostate; S-Nitrosoglutathione; Signal Transduction | 2006 |
Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells.
Topics: Angiotensin II; Aniline Compounds; Animals; Aorta; Calcium; Carrier Proteins; Cells, Cultured; Endothelin-1; Fluorescent Dyes; Isometric Contraction; Male; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myosin Light Chains; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Phenylephrine; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents; Xanthenes | 2006 |
Time-dependent expression of renal vaso-regulatory molecules in LPS-induced endotoxemia in rat.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelin-1; Endotoxemia; Kidney; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Endothelin; Renal Circulation; RNA, Messenger; Time Factors; Tumor Necrosis Factor-alpha | 2006 |
Intrapericardial angiotensin II stimulates endothelin-1 and atrial natriuretic peptide formation of the in situ dog heart.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Dogs; Endothelin-1; Heart; Pericardium | 2006 |
[Protein kinase Cdelta is possibly involved in the transition from hypertrophy to apoptosis of myocardiocytes].
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Cardiomegaly; Cell Enlargement; Endothelin-1; Heart Failure; Myocytes, Cardiac; Primary Cell Culture; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley | 2006 |
Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Carrier Proteins; Cells, Cultured; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression; Homer Scaffolding Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Protein Isoforms; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors | 2006 |
An autocrine role for leptin in mediating the cardiomyocyte hypertrophic effects of angiotensin II and endothelin-1.
Topics: Adipocytes; Angiotensin II; Animals; Animals, Newborn; Autocrine Communication; Cardiomegaly; Cells, Cultured; Endothelin-1; Gene Expression Regulation; Heart Ventricles; Leptin; MAP Kinase Signaling System; Myocytes, Cardiac; Obesity; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2006 |
Autocrine effects of endothelin on in vitro proliferation of vascular smooth muscle cells from spontaneously hypertensive and normotensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Autocrine Communication; Cell Proliferation; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hemostatics; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Signal Transduction; Thrombin; Vasoconstrictor Agents | 2006 |
[Angiotensin II-induced endothelin-1 release in cardiac myocytes].
Topics: Analysis of Variance; Angiotensin II; Animals; Cats; Endothelin-1; Myocardial Contraction; Myocytes, Cardiac; Papillary Muscles; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Calcium Exchanger; Vasoconstrictor Agents | 2006 |
Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients.
Topics: Aged; Aldosterone; AMP Deaminase; Angiotensin II; Atrial Natriuretic Factor; Endothelin-1; Epinephrine; Female; Genotype; Heart Failure; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Natriuretic Peptide, Brain; Norepinephrine; Polymorphism, Genetic; Proportional Hazards Models; Retrospective Studies | 2006 |
Antioxidant actions contribute to the antihypertrophic effects of atrial natriuretic peptide in neonatal rat cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Antioxidants; Atrial Natriuretic Factor; Cell Enlargement; Cells, Cultured; Cyclic N-Oxides; Endothelin-1; Fibroblasts; Gene Expression; Genes, fos; Myocytes, Cardiac; Myosin Heavy Chains; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Spin Labels; Superoxides | 2006 |
Effects of specific endothelin-1 receptor antagonists on proliferation and fibronectin production of glomerular mesangial cells stimulated with Angiotensin II.
Topics: Angiotensin II; Animals; Cell Proliferation; Endothelin A Receptor Antagonists; Endothelin-1; Endothelins; Fibronectins; Glomerular Mesangium; Male; Peptide Fragments; Peptides, Cyclic; Rats; Rats, Sprague-Dawley | 2006 |
Small cytoplasmic domain peptides of natriuretic peptide receptor-C attenuate cell proliferation through Gialpha protein/MAP kinase/PI3-kinase/AKT pathways.
Topics: Amino Acid Sequence; Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Cell Line; Cell Proliferation; Endothelin-1; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Muscle, Smooth, Vascular; Peptide Fragments; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Receptors, Atrial Natriuretic Factor; Signal Transduction; Vasoconstrictor Agents; Wortmannin | 2006 |
Vascular reactivity to various vasoconstrictor agents and endothelium-dependent relaxations of rat thoracic aorta in the long-term period of pinealectomy.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Clonidine; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Endothelium, Vascular; Heart; In Vitro Techniques; Male; Organ Size; Phenylephrine; Pineal Gland; Rats; Rats, Wistar; Serotonin; Time Factors; Vasoconstrictor Agents; Vasodilation; Vasopressins | 2006 |
Intracellular peptides of natriuretic peptide receptor-C inhibit vascular hypertrophy via Gqalpha/MAP kinase signaling pathways.
Topics: Androstadienes; Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Blotting, Western; Cell Line; Cell Proliferation; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Flavonoids; GTP-Binding Protein alpha Subunits, Gq-G11; Leucine; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Peptide Fragments; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Stimulation, Chemical; Wortmannin | 2006 |
The calcium paradoxon of renin release: calcium suppresses renin exocytosis by inhibition of calcium-dependent adenylate cyclases AC5 and AC6.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Exocytosis; In Vitro Techniques; Intracellular Membranes; Isoproterenol; Kidney; Mice; Mice, Inbred C57BL; Renin; RNA, Small Interfering; Thapsigargin | 2006 |
Statin treatment upregulates vascular neuronal nitric oxide synthase through Akt/NF-kappaB pathway.
Topics: Angiotensin II; Animals; Atorvastatin; Cells, Cultured; Endothelin-1; Gene Expression Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mevalonic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Pyrroles; Rats; Rats, Sprague-Dawley; Up-Regulation | 2007 |
Mechanisms of endothelin-1-induced MAP kinase activation in adrenal glomerulosa cells.
Topics: Angiotensin II; Animals; Cattle; Cell Proliferation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Endothelin-1; Enzyme Activation; ErbB Receptors; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Immunoblotting; Immunoprecipitation; Matrix Metalloproteinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Small-Conductance Calcium-Activated Potassium Channels; Zona Glomerulosa | 2006 |
Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Body Weight; Endothelial Cells; Endothelin-1; Enzyme Inhibitors; In Vitro Techniques; Losartan; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Nitroprusside; Obesity; Potassium Chloride; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Fat intake modifies vascular responsiveness and receptor expression of vasoconstrictors: implications for diet-induced obesity.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blotting, Western; Cholesterol; Dietary Fats; Endothelin-1; Endothelium, Vascular; Gene Expression; Glucose Tolerance Test; Hydroxyl Radical; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Obesity; Receptors, Angiotensin; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Endothelin-1 and angiotensin II contribute to BNP but not c-fos gene expression response to elevated load in isolated mice hearts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Coronary Circulation; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Gene Expression Regulation; Genes, fos; Heart; Heart Ventricles; In Vitro Techniques; Male; Mice; Natriuretic Peptide, Brain; Receptor, Angiotensin, Type 1; Tetrazoles; Up-Regulation | 2007 |
Dual effect of endothelin 1 on angiotensin II-potentiated purinergic neurotransmission in prostatic rat vas deferens.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Kinetics; Male; Prostate; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Synaptic Transmission; Vas Deferens | 2007 |
Abnormally increased endothelin-1 in plasma during the night in obstructive sleep apnea: relation to blood pressure and severity of disease.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Endothelin-1; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxygen; Renin; Sleep Apnea, Obstructive | 2007 |
Potential for endothelin-1-mediated impairment of contractile activity in hypertension.
Topics: Aerobiosis; Angiotensin II; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Hindlimb; Hyperemia; Hypertension; Norepinephrine; Oxygen Consumption; Physical Exertion; Rats; Rats, Wistar; Regional Blood Flow; Serotonin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2007 |
Human urotensin-II potentiates the mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells: comparison with other vasoactive agents and hydrogen peroxide.
Topics: Aldehydes; Angiotensin II; Animals; Aorta, Thoracic; Cells, Cultured; DNA; Drug Synergism; Endothelin-1; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Lysophosphatidylcholines; Male; Mitogens; Muscle, Smooth, Vascular; Oxidants; Rabbits; Serotonin; Serotonin Agents; Signal Transduction; Thromboxane A2; Urotensins; Vasoconstrictor Agents | 2006 |
Positive association, in local release, of luteal oxytocin with endothelin 1 and prostaglandin F2alpha during spontaneous luteolysis in the cow: a possible intermediatory role for luteolytic cascade within the corpus luteum.
Topics: Angiotensin II; Animals; Cattle; Corpus Luteum; Dinoprost; Endothelin-1; Female; Luteal Cells; Luteolysis; Oxytocin; Signal Transduction | 2007 |
Changes in the messenger RNA expressions of the endothelin-1 and angiotensin systems in mature follicles of the superovulated bovine ovary.
Topics: Angiotensin II; Animals; Aspartic Acid Endopeptidases; Cattle; Endothelin-1; Endothelin-Converting Enzymes; Female; Metalloendopeptidases; Ovarian Follicle; Ovulation; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger | 2007 |
NADPH oxidase mediates angiotensin II-induced endothelin-1 expression in vascular adventitial fibroblasts.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetophenones; Adenoviridae; Angiotensin II; Animals; Antioxidants; Aorta; Biomarkers; Catecholamines; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Connective Tissue; Cyclic N-Oxides; Dopamine Agonists; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Fibroblasts; Gene Expression; Genetic Vectors; Image Processing, Computer-Assisted; Imidazolines; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidases; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Precursors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spin Labels; Superoxide Dismutase; Transduction, Genetic | 2007 |
Endothelin-1 antisense oligonucleotide suppresses the proliferation of glomerular mesangial cells stimulated with angiotensin-II.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Endothelin-1; Male; Mesangial Cells; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Thymidine | 2007 |
Vasoactive peptides upregulate mRNA expression and secretion of vascular endothelial growth factor in human airway smooth muscle cells.
Topics: Angiotensin II; Animals; Asthma; Cell Proliferation; Culture Media, Conditioned; Endothelin-1; Endothelium, Vascular; Gene Expression Regulation; Humans; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Peptides; Swine; Trachea; Vascular Endothelial Growth Factor A | 2007 |
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Atrasentan; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Activation; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Male; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrrolidines; Rats; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Tetrazoles; Time Factors; Tyrphostins; Vasodilation | 2007 |
Effect of chronic IL-6 infusion on acute pressor responses to vasoconstrictors in mice.
Topics: Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Heart Rate; Hypertension; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pressoreceptors; Vasoconstrictor Agents | 2007 |
Loss of myocardial LIF receptor in experimental heart failure reduces cardiotrophin-1 cytoprotection. A role for neurohumoral agonists?
Topics: Aldosterone; Angiotensin II; Animals; Apoptosis; Cells, Cultured; Cytokines; Cytoprotection; Endothelin-1; Heart Failure; In Situ Nick-End Labeling; Leukemia Inhibitory Factor; Myocardium; Myocytes, Cardiac; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, OSM-LIF; RNA, Messenger | 2007 |
Endothelin-1, but not Ang II, activates MAP kinases through c-Src independent Ras-Raf dependent pathways in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cells, Cultured; CSK Tyrosine-Protein Kinase; Endothelin-1; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Monomeric GTP-Binding Proteins; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Protein-Tyrosine Kinases; src-Family Kinases | 2007 |
Forever young?: nerve growth factor, sympathetic fibers, and right ventricle pressure overload.
Topics: Adrenergic Fibers; Angiotensin II; Animals; Calcium; Endothelin-1; Heart Failure; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Mice; Nerve Growth Factor; Rats; Tyrosine 3-Monooxygenase; Vasoconstriction; Ventricular Dysfunction, Right | 2007 |
Regulator of G protein signalling 2 ameliorates angiotensin II-induced hypertension in mice.
Topics: Angiotensin II; Animals; Arterioles; Baroreflex; Blood Pressure; Disease Models, Animal; Endothelin-1; Epinephrine; Heart Rate; Hypertension; Male; Mice; Mice, Knockout; Norepinephrine; Phenylephrine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RGS Proteins; Vasoconstriction; Vasoconstrictor Agents | 2007 |
[Peroxisome proliferator-activated receptor activator troglitazone inhibits angiotensin II-stimulated secretion of vasoactive factors by endothelial cells].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cell Line; Chromans; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Gene Expression Regulation; Humans; Hypertension; Immunohistochemistry; Losartan; Nitric Oxide; PPAR gamma; Receptor, Angiotensin, Type 1; Thiazolidinediones; Troglitazone | 2007 |
Modeling hypertrophic IP3 transients in the cardiac myocyte.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Cell Membrane; Endothelin-1; Ferrets; Inositol 1,4,5-Trisphosphate; Models, Biological; Models, Theoretical; Myocytes, Cardiac; Phospholipase C beta; Phosphorylation; Rats; Receptors, G-Protein-Coupled; Signal Transduction | 2007 |
Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage.
Topics: Angiotensin II; Animals; Autoradiography; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Endothelin B; Receptor, Serotonin, 5-HT1B; RNA, Messenger; Serotonin; Subarachnoid Hemorrhage; Time Factors; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents | 2007 |
Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes.
Topics: Angiotensin II; Animals; Calcineurin; Calcium; Calcium-Binding Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Cells, Cultured; Endothelin-1; Immunohistochemistry; Indazoles; Phenylephrine; Phosphorylation; Rats; Rats, Wistar | 2007 |
Endothelin-1 in humans is increased by oxygen-derived radicals ex vivo and in vivo.
Topics: Angiotensin II; Catalase; Endothelin-1; Fluorescent Antibody Technique; Free Radical Scavengers; Free Radicals; Humans; In Vitro Techniques; Mammary Arteries; Oxidative Stress; Oxypurinol; Reactive Oxygen Species; Superoxide Dismutase; Xanthine; Xanthine Oxidase | 2007 |
Persistent agonist-induced vasoconstriction is not required for angiotensin II to mediate inward remodeling of isolated arterioles with myogenic tone.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Arterioles; Drug Administration Schedule; Endothelin-1; In Vitro Techniques; Male; Norepinephrine; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasomotor System | 2008 |
Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/ AKT pathway.
Topics: Angiotensin II; Animals; Blood Proteins; Cells, Cultured; Connectin; Endothelin-1; Female; Gene Expression Regulation, Developmental; Heart; Isomerism; Muscle Proteins; Myocardial Contraction; Myocytes, Cardiac; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Stress, Mechanical; Triiodothyronine; Vasoconstrictor Agents | 2008 |
Tetramethylpyrazine inhibits angiotensin II-increased NAD(P)H oxidase activity and subsequent proliferation in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; DNA; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Male; Muscle, Smooth, Vascular; NADPH Oxidases; Pyrazines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Transcription Factor AP-1; Vasodilator Agents | 2007 |
Regional heterogeneity of functional changes in conduit arteries after high-fat diet.
Topics: Acetylcholine; Angiotensin II; Animals; Atherosclerosis; Carotid Arteries; Dietary Fats; Endothelin-1; Femoral Artery; Hydroxyl Radical; Male; Mice; Mice, Inbred C57BL; Obesity; Reactive Oxygen Species; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors.
Topics: Angiotensin II; Animals; Cattle; Cell Culture Techniques; Cell Size; Cells, Cultured; Cyclic Nucleotide-Gated Cation Channels; Endothelin A Receptor Antagonists; Endothelin-1; Fetal Blood; Heart Ventricles; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Peptides, Cyclic; Phenylephrine; Protein Isoforms; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Suppression of cardiac myocyte hypertrophy by conjugated linoleic acid: role of peroxisome proliferator-activated receptors alpha and gamma.
Topics: Angiotensin II; Animals; Dietary Supplements; Diglycerides; Endothelin-1; Fibroblast Growth Factors; Hypertrophy; Linoleic Acids, Conjugated; Models, Biological; Myocytes, Cardiac; PPAR alpha; PPAR gamma; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley | 2008 |
In vitro effect of cyclosporine-A on angiotensins secretion by glomerular cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Female; Immunosuppressive Agents; Kidney Glomerulus; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors; Tissue Culture Techniques; Up-Regulation | 2008 |
Regulation of endothelin-1 release from human endothelial cells by sex steroids and angiotensin-II.
Topics: Angiotensin II; Aorta; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Endothelium; Endothelium, Vascular; Estradiol; Gene Expression Regulation; Gonadal Steroid Hormones; Humans; RNA, Messenger; Stimulation, Chemical; Testosterone | 2008 |
Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Endothelial Cells; Endothelin-1; Epoprostenol; Free Radical Scavengers; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophils; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Kinase Inhibitors; Time Factors; Tyrosine; Up-Regulation | 2008 |
Expression of human endothelin-converting enzyme isoforms: role of angiotensin II.
Topics: Aged; Alternative Splicing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Aspartic Acid Endopeptidases; Base Sequence; Cells, Cultured; Coronary Artery Bypass; DNA Primers; Endothelial Cells; Endothelin-1; Endothelin-Converting Enzymes; Female; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Male; Mammary Arteries; Metalloendopeptidases; Middle Aged; RNA, Messenger | 2008 |
ETA-receptor blockade impairs vasoconstriction after hemorrhage in xenon-anesthetized dogs treated with an AT1-receptor antagonist.
Topics: Anesthesia; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrasentan; Blood Pressure; Dogs; Endothelin A Receptor Antagonists; Endothelin-1; Female; Hemodynamics; Hemorrhage; Losartan; Pyrrolidines; Vascular Resistance; Vasoconstriction; Vasopressins; Xenon | 2008 |
Endothelin (ET)-1 inhibits nicotinamide adenine dinucleotide phosphate oxidase activity in human abdominal aortic endothelial cells: a novel function of ETB1 receptors.
Topics: Angiotensin II; Aorta, Abdominal; Calcium; Cell Division; Cell Line; Endothelial Cells; Endothelin-1; Enzyme Activation; Focal Adhesion Kinase 2; Humans; Membrane Glycoproteins; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Phosphorylation; Proliferating Cell Nuclear Antigen; rac1 GTP-Binding Protein; Reactive Oxygen Species; Receptor, Endothelin B; RNA Interference; Superoxides; Vasoconstrictor Agents | 2008 |
Bibliography. Current world literature. Hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Cannabinoid Receptor Modulators; Diabetes Complications; Endothelin-1; Genetic Therapy; Heart; Humans; Hypertension; Peptidyl-Dipeptidase A; Pharmacogenetics; Social Class; Sodium Chloride, Dietary; Stress, Physiological | 2008 |
Statins suppress MMP2 secretion via inactivation of RhoA/ROCK pathway in pulmonary vascular smooth muscles cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Matrix Metalloproteinase 2; Muscle, Smooth, Vascular; Pulmonary Artery; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Simvastatin | 2008 |
The positive inotropic effect of endothelin-1 is mediated by mitochondrial reactive oxygen species.
Topics: Angiotensin II; Animals; Cardiotonic Agents; Cats; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Free Radical Scavengers; Glycine; Heart Ventricles; Mitochondria, Heart; Myocardial Contraction; Myocytes, Cardiac; NADPH Oxidases; Potassium Channel Blockers; Potassium Channels; Sarcomeres; Sodium-Hydrogen Exchangers; Sulfhydryl Compounds; Superoxides; Vasoconstrictor Agents | 2008 |
Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cell Separation; Cells, Cultured; Coculture Techniques; Diuretics, Osmotic; Endothelin-1; Fibrosis; Leucine; Mannitol; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; Thymidine; Transforming Growth Factor beta1; Tritium | 2008 |
Aldosterone induces interleukin-18 through endothelin-1, angiotensin II, Rho/Rho-kinase, and PPARs in cardiomyocytes.
Topics: Aldosterone; Angiotensin II; Animals; Animals, Newborn; Bezafibrate; Cells, Cultured; DNA Primers; Dose-Response Relationship, Drug; Endothelin-1; Interleukin-18; Myocytes, Cardiac; NF-kappa B; Oligopeptides; Peptides, Cyclic; Peroxisome Proliferator-Activated Receptors; Pioglitazone; Piperidines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Thiazolidinediones | 2008 |
Increased blood pressure in mice lacking cytochrome P450 2J5.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arterioles; Blood Pressure; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Endothelin-1; Estradiol; Estrogen Replacement Therapy; Female; Follicle Stimulating Hormone; Kidney Tubules, Proximal; Luteinizing Hormone; Male; Mice; Ovary; Sex Factors; Testosterone; Vasoconstrictor Agents | 2008 |
Role of angiotensin II, endothelin-1 and L-type calcium channel in the development of glomerular, tubulointerstitial and perivascular fibrosis.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Calcium Channels, L-Type; Disease Models, Animal; Endothelin-1; Fibrosis; Kidney Failure, Chronic; Kidney Glomerulus; Kidney Tubules; Male; Rats | 2008 |
Impaired angiotensin II-extracellular signal-regulated kinase signaling in failing human ventricular myocytes.
Topics: Adult; Angiotensin II; Cardiomyopathy, Dilated; Case-Control Studies; Cells, Cultured; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Myocytes, Cardiac | 2008 |
1,4,5-Inositol trisphosphate-operated intracellular Ca(2+) stores and angiotensin-II/endothelin-1 signaling pathway are functional in human embryonic stem cell-derived cardiomyocytes.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Embryonic Stem Cells; Endothelin-1; Enzyme Inhibitors; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mice; Models, Biological; Myocytes, Cardiac; Receptors, Adrenergic, beta; Signal Transduction | 2008 |
High glucose increases the expression of Gq/11alpha and PLC-beta proteins and associated signaling in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Line; Diabetes Mellitus, Experimental; Endothelin-1; Glucose; GTP-Binding Protein alpha Subunits, Gq-G11; Inositol 1,4,5-Trisphosphate; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phospholipase C beta; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Time Factors | 2008 |
Differential [Ca2+]i signaling of vasoconstriction in mesenteric microvessels of normal and reduced uterine perfusion pregnant rats.
Topics: Angiotensin II; Animals; Calcium Signaling; Disease Models, Animal; Endothelin-1; Feedback, Physiological; Female; Hypertension, Pregnancy-Induced; Litter Size; Mesentery; Microcirculation; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Pregnancy; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Uterus; Vasoconstriction; Vasoconstrictor Agents | 2008 |
Regulation of ACE2 in cardiac myocytes and fibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Atrial Natriuretic Factor; Butadienes; Cells, Cultured; Endothelin-1; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Heart Ventricles; Losartan; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Nitriles; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction | 2008 |
Dopamine D2 receptor stimulation inhibits angiotensin II-induced hypertrophy in cultured neonatal rat ventricular myocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Bromocriptine; Calcium Signaling; Cardiomegaly; Cells, Cultured; Dopamine Agonists; Dopamine Antagonists; Endothelin-1; Haloperidol; Heart Ventricles; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Protein Kinase C; Rats; Rats, Wistar; Receptors, Dopamine D2 | 2009 |
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Angiotensins; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Hypertension; Hyperuricemia; KATP Channels; Kidney; Kidney Diseases; Male; Nitric Oxide; Oxonic Acid; Propylamines; Rats; Rats, Sprague-Dawley; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2008 |
Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelin A Receptor Antagonists; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Hypertension; Insulin; Losartan; Male; Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Receptor, Endothelin A; Streptozocin; Vasoconstriction | 2008 |
Urotensin II-induced increase in myocardial distensibility is modulated by angiotensin II and endothelin-1.
Topics: Angiotensin II; Animals; Endothelin-1; Heart; Male; Myocardium; Rabbits; Urotensins | 2009 |
Endogenous aldosterone contributes to acute angiotensin II-stimulated plasminogen activator inhibitor-1 and preproendothelin-1 expression in heart but not aorta.
Topics: Aldosterone; Angiotensin II; Animals; Aorta; Blood Pressure; Cytochrome P-450 CYP11B2; Drug Interactions; Endothelin-1; Heart; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Time Factors; Up-Regulation | 2009 |
Endothelin-1 modulates angiotensin II in the development of hypertension in fructose-fed rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dietary Carbohydrates; Endothelin-1; Fructose; Glucose Tolerance Test; Hypertension; Imidazoles; Immunohistochemistry; Insulin Resistance; Male; Rats; Rats, Wistar; Tetrazoles | 2009 |
Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.
Topics: Angiotensin II; Animals; Arginine Vasopressin; Butadienes; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Male; MAP Kinase Kinase Kinases; Mesenteric Arteries; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitriles; Nitroarginine; Nitroprusside; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Vasoconstriction; Vasodilation | 2009 |
Role of 20-hydroxyeicosatetraenoic acid in altering vascular reactivity in diabetes.
Topics: Amidines; Angiotensin II; Animals; Blood Glucose; Body Weight; Carbachol; Cytochrome P-450 CYP4A; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Histamine; Hydroxyeicosatetraenoic Acids; Kidney; Male; Mesenteric Arteries; Microsomes; Nitroprusside; Norepinephrine; Perfusion; Rats; Rats, Wistar; Renal Artery; Triazoles; Vasoconstriction; Vasodilation | 2009 |
Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Endothelin-1; Hydralazine; Hypertension, Malignant; Losartan; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency | 2009 |
Correlation of soluble gp130 serum concentrations with arterial blood pressure.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Animals; Aorta, Abdominal; Aorta, Thoracic; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Determination; Carotid Arteries; Case-Control Studies; Cell Culture Techniques; Cells, Cultured; Cytokine Receptor gp130; Endothelin-1; Female; Gene Expression; Heart Rate; Humans; Immunohistochemistry; Male; Middle Aged; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Species Specificity; Stroke; Telemetry; Telmisartan; Time Factors; Tunica Intima; Tunica Media; Vasoconstrictor Agents; Young Adult | 2009 |
Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart.
Topics: Acetophenones; Angiotensin II; Animals; Diastole; Dose-Response Relationship, Drug; Endocardium; Endothelin Receptor Antagonists; Endothelin-1; Endothelium; Enzyme Inhibitors; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Papillary Muscles; Peptides, Cyclic; Rabbits; Receptors, Endothelin | 2009 |
Mice lacking the ADP ribosyl cyclase CD38 exhibit attenuated renal vasoconstriction to angiotensin II, endothelin-1, and norepinephrine.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Angiotensin II; Animals; Antigens, CD; Arterioles; Blood Pressure; Endothelin-1; GPI-Linked Proteins; Heart Rate; Kidney; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Niacinamide; Norepinephrine; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vitamin B Complex | 2009 |
Effect of sodium houttuyfonate on myocardial hypertrophy in mice and rats.
Topics: Alkanes; Angiotensin II; Animals; Captopril; Cardiomegaly; Cyclic AMP; Dose-Response Relationship, Drug; Endothelin-1; Hydroxyproline; Isoproterenol; Male; Mice; Myocardium; Myocytes, Cardiac; Organ Size; Rats; Rats, Sprague-Dawley; Sulfites; Thyroxine | 2009 |
Endothelin-I and angiotensin II inhibit arterial voltage-gated K+ channels through different protein kinase C isoenzymes.
Topics: Angiotensin II; Animals; Cell Membrane Permeability; Endothelin-1; Gene Products, tat; In Vitro Techniques; Isoenzymes; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Myography; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Vasoconstriction | 2009 |
L-Carnitine attenuates angiotensin II-induced proliferation of cardiac fibroblasts: role of NADPH oxidase inhibition and decreased sphingosine-1-phosphate generation.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiotonic Agents; Carnitine; Cell Proliferation; Cells, Cultured; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Regulation; Heart; Lysophospholipids; Myocardium; NADPH Oxidases; Osmolar Concentration; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Sphingosine; Transcription Factor AP-1 | 2010 |
Characterization of promoter elements required for cardiac chamber-specific expression.
Topics: Angiotensin II; Animals; Base Sequence; Binding Sites; Electrophoretic Mobility Shift Assay; Endothelin-1; Fish Proteins; GATA Transcription Factors; Gene Expression Regulation; Heart Ventricles; Molecular Sequence Data; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Natriuretic Peptides; Organ Specificity; Promoter Regions, Genetic; Protein Binding; Rats; Stress, Mechanical; Transcription Factor AP-1; Transcription Initiation Site | 2009 |
Protective effects of vasonatrin peptide against hypobaric hypoxia-induced pulmonary hypertension in rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Atmospheric Pressure; Atrial Natriuretic Factor; Disease Models, Animal; Endothelin-1; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Atrial Natriuretic Factor | 2010 |
Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease.
Topics: Aged; Angina Pectoris; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Arteries; Blotting, Western; Case-Control Studies; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelin-1; Humans; Imidazoles; Immunohistochemistry; Middle Aged; Muscle, Smooth, Vascular; Myocardial Ischemia; Myography; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Subcutaneous Tissue; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 2009 |
[Establishment of a diabetic-hypertensive rat model].
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Blood Pressure Determination; Diabetes Mellitus, Experimental; Endothelin-1; Hypertension; Kidney; Male; Rats; Rats, Wistar | 2009 |
Control by circulating factors of mitochondrial function and transcription cascade in heart failure: a role for endothelin-1 and angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Down-Regulation; Endothelin-1; Female; Heart Failure; Heat-Shock Proteins; Humans; Male; Middle Aged; Mitochondria, Heart; Oxygen Consumption; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Transcription Factors | 2009 |
Rhythmic supplementation of 17beta-estradiol according to the physiological estrous cycle: effect on blood pressure in female ovariectomized rats.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelin-1; Estradiol; Estrous Cycle; Female; Injections, Subcutaneous; Nitric Oxide Synthase Type III; Ovariectomy; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Receptor, Endothelin B; Renin-Angiotensin System | 2010 |
Renal vasoconstrictor and pressor responses to angiotensin IV in mice are AT1a-receptor mediated.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Base Sequence; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; DNA Primers; Endothelin-1; Hemodynamics; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction | 2010 |
Upregulation of cardiac matrix Gla protein expression in response to hypertrophic stimuli.
Topics: Angiotensin II; Animals; Animals, Newborn; Arginine Vasopressin; Calcium-Binding Proteins; Cells, Cultured; Endothelin-1; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Hypertrophy, Left Ventricular; Male; Matrix Gla Protein; Myocardial Contraction; Myocardial Infarction; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Up-Regulation | 2009 |
Mouse hepatic portal venoconstrictive response to vasoconstrictors is much weaker than that in rat.
Topics: Actins; Angiotensin II; Animals; Central Venous Pressure; Dose-Response Relationship, Drug; Endothelin-1; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth; Norepinephrine; Portal Pressure; Rats; Rats, Sprague-Dawley; Species Specificity; Vasoconstriction; Vasoconstrictor Agents | 2009 |
Influence of exercise and perivascular adipose tissue on coronary artery vasomotor function in a familial hypercholesterolemic porcine atherosclerosis model.
Topics: Adipose Tissue; Angiotensin II; Animals; Atherosclerosis; Bradykinin; Coronary Vessels; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Hyperlipoproteinemia Type II; Male; Nitroprusside; Physical Exertion; Sedentary Behavior; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Role of insulin-like growth factor 1 receptor and c-Src in endothelin-1- and angiotensin II-induced PKB phosphorylation, and hypertrophic and proliferative responses in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Line; Dose-Response Relationship, Drug; Endothelin-1; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins pp60(c-src); Pyrazoles; Pyrimidines; Rats; Receptor, IGF Type 1; src-Family Kinases; Transcriptional Activation; Tyrphostins | 2009 |
Inhibition of endothelin converting enzyme-1 activity or expression ameliorates angiotensin II-induced myocardial hypertrophy in cultured cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Blotting, Western; Cell Size; Cell Survival; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Metalloendopeptidases; Myocytes, Cardiac; Peptides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference | 2009 |
Human embryonic stem cell-derived cardiomyocytes can mobilize 1,4,5-inositol trisphosphate-operated [Ca2+]i stores: the functionality of angiotensin-II/endothelin-1 signaling pathways.
Topics: Angiotensin II; Animals; Calcium; Cell Differentiation; Cell Line; Embryonic Stem Cells; Endothelin-1; Humans; Mice; Mice, Inbred ICR; Myocytes, Cardiac; Signal Transduction | 2010 |
Cardiac lymphatic obstruction impairs left ventricular function and increases plasma endothelin-1 and angiotensin II in rabbits.
Topics: Angiotensin II; Animals; Endothelin-1; Female; Heart Diseases; Lymphatic Diseases; Male; Rabbits; Stroke Volume; Ventricular Dysfunction, Left | 2009 |
Cellular phenotype transformation occurs during thoracic aortic aneurysm development.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Disease Models, Animal; Disease Progression; Endothelin-1; Extracellular Matrix Proteins; Female; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Genotype; Male; Mice; Mice, Inbred C57BL; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Tetradecanoylphorbol Acetate | 2010 |
The Anrep effect requires transactivation of the epidermal growth factor receptor.
Topics: Angiotensin II; Animals; Cats; Endothelin-1; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Mechanoreceptors; Myocardial Contraction; Oxidation-Reduction; Papillary Muscles; Phosphorylation; Reactive Oxygen Species; Receptor Cross-Talk; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Sodium-Hydrogen Exchangers; Superoxides; Transcriptional Activation | 2010 |
The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure.
Topics: Angiotensin II; Animals; Blood Pressure; Cells, Cultured; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Humans; Mesenteric Arteries; Mice; Mice, Transgenic; Receptors, Mineralocorticoid; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells.
Topics: Angiotensin II; Calcium; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diltiazem; Endothelial Cells; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Inflammation; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidase 5; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proliferating Cell Nuclear Antigen; Pyrones; Quinolines; rac1 GTP-Binding Protein; RNA Interference; RNA, Messenger; Signal Transduction; Superoxides; Time Factors; Vascular Cell Adhesion Molecule-1 | 2010 |
Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acute Kidney Injury; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Creatinine; Endothelin-1; Indans; Kidney; Male; Natriuresis; Neprilysin; Nitrates; Propionates; Proteinuria; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Role of vasoactive peptides in high glucose-induced increased expression of Gαq/11 proteins and associated signaling in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Line; Endothelin-1; Glucose; GTP-Binding Protein alpha Subunits, Gq-G11; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phospholipase C beta; Rats; Signal Transduction; Up-Regulation | 2010 |
Endothelin signalling regulates volume-sensitive Cl- current via NADPH oxidase and mitochondrial reactive oxygen species.
Topics: Angiotensin II; Animals; Cell Size; Chloride Channels; Chlorides; Endothelin-1; ErbB Receptors; Flow Cytometry; In Vitro Techniques; Membrane Potentials; Membrane Transport Modulators; Mitochondria, Heart; Myocytes, Cardiac; Osmotic Pressure; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Rabbits; Reactive Oxygen Species; Receptor, Endothelin A; Signal Transduction; Uncoupling Agents | 2010 |
Antihypertensive effects of Ocimum basilicum L. (OBL) on blood pressure in renovascular hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Blood Pressure; Captopril; Cardiomegaly; Disease Models, Animal; Endothelin-1; Endothelin-Converting Enzymes; Hypertension, Renovascular; Kidney; Male; Metalloendopeptidases; Ocimum basilicum; Plant Extracts; Rats; Rats, Wistar | 2010 |
Soluble uric acid increases intracellular calcium through an angiotensin II-dependent mechanism in immortalized human mesangial cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Calcium; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Humans; Losartan; Mesangial Cells; Polymerase Chain Reaction; Uric Acid | 2010 |
Effects of polydatin on attenuating ventricular remodeling in isoproterenol-induced mouse and pressure-overload rat models.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Cardiovascular Agents; Collagen; Cyclic AMP; Drugs, Chinese Herbal; Endothelin-1; Fallopia japonica; Glucosides; Heart; Hypertrophy, Left Ventricular; Isoproterenol; Male; Mice; Myocytes, Cardiac; Organ Size; Phytotherapy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stilbenes; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2010 |
Myocardin-related transcription factor A is a common mediator of mechanical stress- and neurohumoral stimulation-induced cardiac hypertrophic signaling leading to activation of brain natriuretic peptide gene expression.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelin-1; Gene Expression Regulation; Gene Knockdown Techniques; Humans; Male; Mice; Myocytes, Cardiac; Natriuretic Peptide, Brain; Nuclear Proteins; Promoter Regions, Genetic; Protein Transport; Rats; Serum Response Factor; Stress, Mechanical; Trans-Activators | 2010 |
Reduced baroreflex sensitivity and pulmonary dysfunction in alcoholic cirrhosis: effect of hyperoxia.
Topics: Aged; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Baroreflex; Case-Control Studies; Endothelin-1; Female; Humans; Hyperoxia; Liver Cirrhosis, Alcoholic; Lung Diseases; Male; Middle Aged; Natriuretic Peptide, Brain; Norepinephrine; Oxygen; Renin | 2010 |
The IP3 receptor regulates cardiac hypertrophy in response to select stimuli.
Topics: Age Factors; Angiotensin II; Animals; Arrhythmias, Cardiac; Calcineurin; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Endothelin-1; GTP-Binding Protein alpha Subunits, Gq-G11; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Isoproterenol; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocytes, Cardiac; Phenotype; Physical Exertion | 2010 |
Despite similar reduction of blood pressure and renal ANG II and ET-1 levels aliskiren but not losartan normalizes albuminuria in hypertensive Ren-2 rats.
Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Down-Regulation; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fumarates; Hypertension; Kidney; Losartan; Male; Mice; Pilot Projects; Radioimmunoassay; Rats; Rats, Transgenic; Renin; Time Factors | 2010 |
p63RhoGEF--a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Calcium; Cells, Cultured; Endothelin-1; Fluorescent Antibody Technique; Guanine Nucleotide Exchange Factors; Imidazoles; Immunoblotting; Immunohistochemistry; Lysophospholipids; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pyridines; Rats; Rats, Wistar; Serotonin; Signal Transduction; Sphingosine; Telmisartan | 2010 |
Kinin B1 receptor upregulation by angiotensin II and endothelin-1 in rat vascular smooth muscle cells: receptors and mechanisms.
Topics: Angiotensin II; Animals; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Male; Models, Animal; Muscle, Smooth, Vascular; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptor, Endothelin A; RNA, Messenger; Up-Regulation | 2010 |
Apelin mediates the induction of profibrogenic genes in human hepatic stellate cells.
Topics: Analysis of Variance; Angiotensin II; Animals; Apelin; Blotting, Western; Cell Line; Cells, Cultured; Collagen Type I; Endothelin-1; Fluorescent Antibody Technique; Gene Expression; Hepatic Stellate Cells; Humans; Intercellular Signaling Peptides and Proteins; Liver; Liver Cirrhosis; Male; Middle Aged; Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric | 2010 |
Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Cells, Cultured; CSK Tyrosine-Protein Kinase; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Free Radical Scavengers; Hyperplasia; Hypertension; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; src-Family Kinases; Superoxides | 2010 |
Activation of NFATc1 is directly mediated by IP3 in adult cardiac myocytes.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Endothelin-1; Female; Green Fluorescent Proteins; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Male; Models, Animal; Myocytes, Cardiac; NFATC Transcription Factors; Phenylephrine; Rabbits; Signal Transduction | 2010 |
Adrenomedullin attenuates aortic cross-clamping-induced myocardial injury in rats.
Topics: Adrenomedullin; Angiotensin II; Animals; Aorta; Apoptosis; Biomarkers; Caspase 3; Catalase; Constriction; Endothelin-1; Immunohistochemistry; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Troponin I; Tumor Necrosis Factor-alpha | 2011 |
Evidence that apoptotic signalling in hypertrophic cardiomyocytes is determined by mitochondrial pathways involving protein kinase Cδ.
Topics: Acetophenones; Angiotensin II; Animals; Apoptosis; Benzopyrans; Cardiomegaly; Caspase 3; Caspase 9; Cells, Cultured; Endothelin-1; Imidazoles; Insulin-Like Growth Factor I; Mitochondria; Myocytes, Cardiac; Peptides, Cyclic; Protein Kinase C-delta; Protein Transport; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Endothelin; Signal Transduction; Triiodothyronine | 2010 |
Endothelin-1 and angiotensin II modulate rate and contraction amplitude in a subpopulation of mouse embryonic stem cell-derived cardiomyocyte-containing bodies.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Line; Embryonic Stem Cells; Endothelin-1; Mice; Myocardial Contraction; Myocytes, Cardiac | 2011 |
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Culture Techniques; Cell Line; Disease Models, Animal; Endothelin-1; Humans; Myoblasts, Cardiac; Myocytes, Cardiac; Rats | 2011 |
20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.
Topics: Adult; Aged; Amidines; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Platelets; Calcium Channels; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelin-1; Humans; Hydroxyeicosatetraenoic Acids; Imidazoles; Ionophores; Irbesartan; Male; Middle Aged; Neutrophils; Oligopeptides; Peptides, Cyclic; Piperidines; Pyridines; Tetrazoles; Young Adult | 2011 |
Potent and selective inhibition of angiotensin AT1 receptor signaling by RGS2: roles of its N-terminal domain.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Calcium; Endothelin-1; HEK293 Cells; Humans; Male; Mice; Muscle, Smooth, Vascular; Myocardium; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 1; Receptors, Endothelin; Recombinant Fusion Proteins; RGS Proteins; Signal Transduction; Transcription, Genetic | 2011 |
Nicorandil inhibits angiotensin-II-induced proliferation of cultured rat cardiac fibroblasts.
Topics: Angiotensin II; Animals; Animals, Newborn; Cardiotonic Agents; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Fibrosis; Heart Ventricles; Nicorandil; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2011 |
Improved cardiac function after sarcoplasmic reticulum Ca(2+)-ATPase gene transfer in a heart failure model induced by chronic myocardial ischaemia.
Topics: Adenoviridae; Angiotensin II; Animals; Disease Models, Animal; Endothelin-1; Fluorescent Dyes; Gene Transfer Techniques; Genetic Therapy; Green Fluorescent Proteins; Heart Failure; Interleukin-6; Male; Myocardial Infarction; Myocardium; Natriuretic Peptide, Brain; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Stroke Volume; Swine; Swine, Miniature; Tumor Necrosis Factor-alpha | 2011 |
Tanshinone IIA inhibits angiotensin II-induced cell proliferation in rat cardiac fibroblasts.
Topics: Abietanes; Angiotensin II; Animals; Antioxidants; Cell Proliferation; Cells, Cultured; Drugs, Chinese Herbal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; Heart; Myocardium; Myofibroblasts; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Small Interfering; Salvia miltiorrhiza; Signal Transduction; Transfection | 2011 |
Adiponectin opposes endothelin-1-mediated vasoconstriction in the perfused rat hindlimb.
Topics: Adiponectin; Angiotensin II; Animals; DNA, Complementary; Dose-Response Relationship, Drug; Endothelin-1; Glucose; Hindlimb; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Donors; Norepinephrine; Oxygen Consumption; Perfusion; Rats; Rats, Wistar; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents | 2011 |
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Endothelin-1; Enzyme Activation; Infarction, Middle Cerebral Artery; Male; Nitric Oxide Synthase Type II; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke | 2011 |
Proinflammatory role of angiotensin II in a rat nephrosis model induced by adriamycin.
Topics: Angiotensin II; Animals; Cholesterol; Disease Models, Animal; Doxorubicin; Endothelin-1; Fluorescent Antibody Technique; Inflammation; Inflammation Mediators; Kidney; Losartan; Male; Nephrosis; Proteinuria; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides; Weight Gain | 2011 |
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm; Apolipoproteins E; Atherosclerosis; Biomechanical Phenomena; Bosentan; Cardiovascular Agents; Cell Adhesion; Collagen; Down-Regulation; Endothelin-1; Integrin beta1; Interferon-gamma; Mice; Mice, Knockout; Stress, Physiological; Sulfonamides; Vasoconstrictor Agents | 2011 |
Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes.
Topics: Adenoviridae; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Angiotensin II; Animals; Biosensing Techniques; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiac Pacing, Artificial; Endothelin-1; Enzyme Activation; Fluorescence Resonance Energy Transfer; Genetic Vectors; HEK293 Cells; Humans; Isoproterenol; Kinetics; Luminescent Proteins; Microscopy, Confocal; Mutation; Myocytes, Cardiac; Oxidation-Reduction; Phenylephrine; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Rabbits; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection | 2011 |
On the quantitation of an agonist with dual but opposing components of action: application to vascular endothelial relaxation.
Topics: Angiotensin II; Animals; Aorta; Dose-Response Relationship, Drug; Drug Agonism; Drug Interactions; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2011 |
Serine-910 phosphorylation of focal adhesion kinase is critical for sarcomere reorganization in cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Western; Cardiomyopathy, Dilated; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Activation; Fluorescence Recovery After Photobleaching; Focal Adhesion Kinase 1; Heart Failure; Humans; Immunoprecipitation; Insulin-Like Growth Factor I; Microscopy, Fluorescence; Mutation; Myocytes, Cardiac; Paxillin; Phenylephrine; Phosphorylation; Protein Kinase C-delta; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sarcomeres; Serine; Signal Transduction; src-Family Kinases; Time Factors; Transfection | 2011 |
ETA and ETB receptors are expressed in vascular adventitial fibroblasts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Blotting, Western; Cells, Cultured; Collagen Type I; Connective Tissue; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Losartan; Mice; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Time Factors; Viper Venoms | 2011 |
Total saponins of panax ginseng inhibiting human endothelium cells' damages induced by angiotensin II via AT1 receptor.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelin-1; Endothelium, Vascular; Humans; Microscopy, Electron, Scanning; NADPH Oxidases; NF-kappa B; Panax; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Saponins; Vascular Cell Adhesion Molecule-1 | 2011 |
Effects of ethanolic extract from Radix Scrophulariae on ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Chemical Analysis; Captopril; Cardiomegaly; Collagen; Coronary Vessels; Endothelin-1; Ethanol; Gene Expression Regulation; Hemodynamics; Hydroxyproline; Male; Matrix Metalloproteinase 2; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Organ Size; Plant Extracts; Plant Roots; Random Allocation; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Scrophularia; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2012 |
Interleukin 6 underlies angiotensin II-induced hypertension and chronic renal damage.
Topics: Adult; Angiotensin II; Animals; Biopsy; Blood Pressure; Disease Progression; Endothelin-1; Female; Fibrosis; Humans; Hypertension, Renal; Interleukin-6; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Middle Aged; Organ Culture Techniques; Proteinuria; Renal Insufficiency, Chronic; Signal Transduction; Vasoconstrictor Agents | 2012 |
Drugs of the future for Peyronie's disease.
Topics: Adult; Angiotensin II; Animals; Connective Tissue Growth Factor; Disease Models, Animal; Drug Design; Drug Therapy; Endothelin-1; Fibrosis; Humans; Inflammation; Male; Middle Aged; Penile Induration; Platelet-Derived Growth Factor; Transforming Growth Factor beta1; Wound Healing | 2012 |
Mineralocorticoid receptor activation is crucial in the signalling pathway leading to the Anrep effect.
Topics: Aldosterone; Angiotensin II; Animals; Endothelin-1; ErbB Receptors; Heart; In Vitro Techniques; Male; Mitochondria, Heart; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth; Myocardial Contraction; Papillary Muscles; Rats; Rats, Wistar; Receptors, Endothelin; Receptors, Mineralocorticoid; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Sodium-Hydrogen Exchangers; Stress, Mechanical; Superoxides | 2011 |
Connexin 43, angiotensin II, endothelin 1, and type III collagen alterations in heart of rats having undergone fatal electrocution.
Topics: Angiotensin II; Animals; Collagen Type III; Electric Injuries; Endothelin-1; Forensic Pathology; Immunohistochemistry; Microscopy; Myocardium; Rats; Rats, Sprague-Dawley | 2012 |
Angiotensin-(1-7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Collagen; Cyclooxygenase 2; DNA; Dual Specificity Phosphatase 1; Endothelin-1; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart Diseases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptide Fragments; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats; Signal Transduction | 2012 |
ET-1 from endothelial cells is required for complete angiotensin II-induced cardiac fibrosis and hypertrophy.
Topics: Angiotensin II; Animals; Blood Pressure; Blotting, Northern; Blotting, Western; Cardiomegaly; Disease Models, Animal; Endothelial Cells; Endothelin-1; Fibrosis; Gene Expression Regulation; Male; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Polymerase Chain Reaction; Protein Kinase C-delta; Protein Kinase C-epsilon | 2012 |
Nitroxyl (HNO) stimulates soluble guanylyl cyclase to suppress cardiomyocyte hypertrophy and superoxide generation.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Adhesion Molecules; Cyclic GMP; Endothelin-1; Guanylate Cyclase; Microfilament Proteins; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Nitrites; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Rats; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Superoxides | 2012 |
Role of NF-κB and p38 MAPK activation in mediating angiotensin II and endothelin-1-induced stimulation in leptin production and cardiomyocyte hypertrophy.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Animals; Cell Enlargement; Cell Nucleus; Cell Size; Cells, Cultured; Endothelin-1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hypertrophy; Leptin; Myocytes, Cardiac; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Rats; Rats, Sprague-Dawley | 2012 |
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Losartan; MAP Kinase Signaling System; Mesangial Cells; Microscopy, Confocal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transforming Growth Factor beta1 | 2012 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
Loss of renal medullary endothelin B receptor function during salt deprivation is regulated by angiotensin II.
Topics: Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Diet, Sodium-Restricted; Diuresis; Endothelin-1; Endothelin-2; Kidney Medulla; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Sodium Chloride, Dietary; Sodium, Dietary; Tetrazoles; Viper Venoms | 2012 |
Cardiomyocyte-specific transgenic expression of lysyl oxidase-like protein-1 induces cardiac hypertrophy in mice.
Topics: Amino Acid Oxidoreductases; Aminopropionitrile; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Echocardiography; Endothelin-1; In Vitro Techniques; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocytes, Cardiac; Rats; Rats, Wistar | 2012 |
Relaxant effect of a water soluble carbon monoxide-releasing molecule (CORM-3) on spontaneously hypertensive rat aortas.
Topics: Angiotensin II; Animals; Aorta; Carbon Monoxide; Charybdotoxin; Endothelin-1; Endothelium, Vascular; Guanylate Cyclase; Hypertension; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Organometallic Compounds; Potassium Channels, Calcium-Activated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Vasoconstriction; Vasodilation; Vasodilator Agents; Water | 2012 |
[Effects of two different extracts of total saponins from Cicer arietinum on kidney of T2DM rats].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Glucose; Blood Urea Nitrogen; Cicer; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelin-1; Glutathione Peroxidase; Hypoglycemic Agents; Insulin; Kidney; Male; Malondialdehyde; Plants, Medicinal; Random Allocation; Rats; Rats, Wistar; Saponins; Superoxide Dismutase; Thromboxane B2 | 2012 |
An intact kidney slice model to investigate vasa recta properties and function in situ.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antigens; Capillaries; Cell Survival; Endothelin-1; Enzyme Inhibitors; Immunohistochemistry; In Vitro Techniques; Indomethacin; Kidney Medulla; Male; Microscopy, Confocal; NG-Nitroarginine Methyl Ester; Norepinephrine; Pericytes; Proteoglycans; Rats; Rats, Sprague-Dawley; Signal Transduction; Sympathetic Nervous System; Vasoconstriction; Vasoconstrictor Agents | 2012 |
[Effects of extracts of Radix Scrophulariae on blood pressure in spontaneously hypertensive rats and the underlying mechanisms].
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Drugs, Chinese Herbal; Endothelin-1; Hypertension; Male; Norepinephrine; Phytotherapy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Scrophularia; Thromboxane B2 | 2012 |
[Pharmacodynamic study of racemic TJ0711 on renal hypertensive rats after long-term administration].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelin-1; Female; Heart Rate; Heart Ventricles; Hydroxyproline; Hypertension, Renal; Longitudinal Studies; Male; Malondialdehyde; Organ Size; Phenoxypropanolamines; Random Allocation; Rats; Rats, Wistar; Renin | 2012 |
Artificial cold air increases the cardiovascular risks in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Chemical Analysis; Blood Pressure; Blood Viscosity; Body Weight; Cardiovascular Diseases; Cold Temperature; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Epinephrine; Fibrinogen; Heart Rate; Lipids; Male; Norepinephrine; Rats; Rats, Inbred SHR; Risk Factors; Vasoconstrictor Agents | 2012 |
Elevations of local intravascular pressures release vasoactive substances in humans.
Topics: Adaptation, Physiological; Adult; Analysis of Variance; Angiotensin II; Arterial Pressure; Biomarkers; Blood Flow Velocity; Brachial Artery; Endothelin-1; Fibroblast Growth Factor 2; Heart Rate; Humans; Male; Plethysmography, Impedance; Regional Blood Flow; Time Factors; Ultrasonography, Doppler; Up-Regulation; Upper Extremity; Vascular Endothelial Growth Factor A; Vascular Stiffness; Vasoconstriction; Vasodilation; Young Adult | 2013 |
Nebivolol treatment improves resistant arterial function and reduces ventricular hypertrophy and angiotensin II in spontaneously hypertension rats.
Topics: Acetylcholine; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Body Weight; Endothelin-1; Ethanolamines; Femoral Artery; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Nebivolol; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Renal Artery; Renin-Angiotensin System; Systole; Vascular Resistance | 2013 |
Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelin-1; Hypertrophy; Leptin; Male; Myocytes, Cardiac; Pressure; Protein Isoforms; Rats; Rats, Wistar; Receptors, Leptin; RNA, Messenger; STAT3 Transcription Factor; Stress, Mechanical; Up-Regulation | 2012 |
Atrial natriuretic peptide exerts protective action against angiotensin II-induced cardiac remodeling by attenuating inflammation via endothelin-1/endothelin receptor A cascade.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelin-1; Fibrillar Collagens; Fibroblasts; Fibrosis; Heart Diseases; Inflammation; Inflammation Mediators; Infusions, Intravenous; Macrophages; Male; Mitral Valve; Myocardial Contraction; Myocardium; Rats; Rats, Inbred WKY; Receptor, Endothelin A; Signal Transduction; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2013 |
[Adenosine receptors agonists mitigated PAH of rats induced by chronic hypoxia through reduction of renin activity/angiotensin II levels and increase of inducible nitric oxide synthase-nitric oxide levels].
Topics: Adenosine; Angiotensin II; Animals; Disease Models, Animal; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Proliferating Cell Nuclear Antigen; Pulmonary Artery; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Renin | 2012 |
MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteries.
Topics: Angiotensin II; Butadienes; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscles; Myography; Nitriles; Organ Culture Techniques; Receptor, Endothelin A; Receptor, Endothelin B; Receptor, Serotonin, 5-HT1B; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Thromboxane; Signal Transduction | 2013 |
[Effects of angiotensin II and its receptor blockers on migration and endothelin-1 expression of rat vascular adventitial fibroblast subpopulations].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Movement; Cells, Cultured; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents | 2012 |
Apelin effects on blood pressure and RAS in DOCA-salt-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Aorta; Apelin; Apelin Receptors; Blood Pressure; Desoxycorticosterone Acetate; Endothelin-1; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2013 |
[Research of sapindus saponins on endothelial function in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Aorta, Thoracic; Endothelin-1; Endothelium, Vascular; Female; Male; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sapindus; Saponins | 2012 |
Exercise reduces angiotensin II responses in rat femoral veins.
Topics: Adaptation, Physiological; Angiotensin II; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Endothelin-1; Femoral Vein; Gene Expression; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Peptides, Cyclic; Physical Conditioning, Animal; Physical Exertion; Piperidines; Rats; Vasoconstriction | 2013 |
Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.
Topics: 5'-Nucleotidase; Adenosine; Adult; Angiotensin II; Animals; Cells, Cultured; Chronic Disease; Endothelial Cells; Endothelin-1; Female; Gene Expression; GPI-Linked Proteins; Humans; Hypertension, Renal; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Receptor, Adenosine A2B; Signal Transduction; Vasoconstrictor Agents | 2013 |
Angiotensin II induces endothelin-1 expression in human hepatic stellate cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Cells, Cultured; Endothelin-1; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Renin-Angiotensin System | 2013 |
Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.
Topics: Angiotensin II; Cerebral Arteries; Endothelin-1; Female; Gene Expression; Humans; Male; Middle Aged; Myography; Organ Culture Techniques; Protein Isoforms; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Serotonin, 5-HT1B; RNA, Messenger; Sex Factors; Signal Transduction; Vasoconstriction | 2013 |
Functional transient receptor potential canonical type 1 channels in human atrial myocytes.
Topics: Action Potentials; Angiotensin II; Calcium Channels; Calcium Signaling; Cells, Cultured; Endothelin-1; Heart Atria; Humans; Lanthanum; Membrane Proteins; Myocytes, Cardiac; Neoplasm Proteins; ORAI1 Protein; RNA, Messenger; Stromal Interaction Molecule 1; Thapsigargin; TRPC Cation Channels | 2013 |
Protective effects of ginaton on vascular endothelial cells injured by angiotensin II and hypoxia in vitro.
Topics: Angiotensin II; Cell Hypoxia; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Endothelin-1; Humans; Membrane Potential, Mitochondrial; Time Factors | 2013 |
Angiotensin II regulates microRNA-132/-212 in hypertensive rats and humans.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelin-1; Female; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Organ Specificity; Rats, Sprague-Dawley; Reproducibility of Results; Vasoconstrictor Agents | 2013 |
Effect of CCL5 on dimethylarginine dimethylaminohydrolase-1 production in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Arginine; Blood Pressure; Cell Proliferation; Chemokine CCL5; Endothelin-1; Hypertension; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; RNA Interference; RNA, Small Interfering | 2013 |
The effect of intermedin on angiotensin II and endothelin-1 induced ventricular myocyte hypertrophy in neonatal rat.
Topics: Actins; Adrenomedullin; Analysis of Variance; Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cell Size; Cells, Cultured; Drug Interactions; Endothelin-1; Gene Expression; Heart Ventricles; Membrane Glycoproteins; Myocytes, Cardiac; Myosin Heavy Chains; NADPH Oxidase 2; NADPH Oxidases; Neuropeptides; Protective Agents; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2013 |
Effect of aerobic exercise on miRNA-TLR4 signaling in atherosclerosis.
Topics: Angiotensin II; Animals; Atherosclerosis; Disease Models, Animal; Endothelin-1; Epidermal Growth Factor; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; MicroRNAs; NF-kappa B; Physical Conditioning, Animal; Signal Transduction; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4 | 2014 |
Role of expression of endothelin-1 and angiotensin-II and hypoxia-inducible factor-1α in the kidney tissues of patients with diabetic nephropathy.
Topics: Adult; Aged; Angiotensin II; Diabetic Nephropathies; Disease Progression; Endothelin-1; Female; Fibrosis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kidney; Male; Middle Aged; Nephritis, Interstitial | 2013 |
Endothelin-1, oxidative stress, and endogenous angiotensin II: mechanisms of angiotensin II type I receptor autoantibody-enhanced renal and blood pressure response during pregnancy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Autoantibodies; Blood Pressure; Enalapril; Endothelin-1; Female; Hypertension, Pregnancy-Induced; Kidney; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2013 |
The effects of high thoracic epidural anesthesia on sympathetic activity and apoptosis in experimentally induced congestive heart failure.
Topics: Anesthesia, Epidural; Anesthetics, Local; Angiotensin II; Animals; Apoptosis; Apoptosis Inducing Factor; DNA Repair; Endothelin-1; Heart Failure; Lidocaine; Male; Myocardium; Norepinephrine; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Sympathetic Nervous System; Thoracic Vertebrae; Tissue Fixation; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2014 |
Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes.
Topics: Actin Depolymerizing Factors; Actins; Angiotensin II; Animals; Cardiomegaly; Cell Nucleus; Endothelin-1; Enzyme Activation; Models, Biological; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polymerization; Protein Transport; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein | 2014 |
Intrinsic-mediated caspase activation is essential for cardiomyocyte hypertrophy.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Bronchodilator Agents; Cardiomegaly; Caspase 3; Caspase 9; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelin-1; Enzyme Activation; Fluorescent Antibody Technique; Hypertrophy; In Vitro Techniques; Isoproterenol; Membrane Potential, Mitochondrial; Myocardium; Myocytes, Cardiac; Oligopeptides; Phenylephrine; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasoconstrictor Agents | 2013 |
Aldosterone secretagogues increase adrenal blood flow in male rats.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Arterial Pressure; Endothelin-1; Laser-Doppler Flowmetry; Male; Nitroprusside; Rats; Rats, Sprague-Dawley; Steroids; Vasoconstrictor Agents | 2014 |
Endogenous endothelin 1 mediates angiotensin II-induced hypertrophy in electrically paced cardiac myocytes through EGFR transactivation, reactive oxygen species and NHE-1.
Topics: Angiotensin II; Animals; Blotting, Western; Cardiomegaly; Cats; Disease Models, Animal; Electric Stimulation; Endothelin-1; ErbB Receptors; Hypertrophy; Myocytes, Cardiac; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Signal Transduction; Sodium-Hydrogen Exchangers; Transcriptional Activation | 2014 |
Regulating effect of tea polyphenols on endothelin, intracellular calcium concentration, and mitochondrial membrane potential in vascular endothelial cells injured by Angiotensin II.
Topics: Angiotensin II; Calcium; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Endothelial Cells; Endothelin-1; Humans; Membrane Potential, Mitochondrial; Mitochondria; Phytotherapy; Plant Extracts; Plants, Medicinal; Polyphenols; RNA, Messenger; Tea; Time Factors; Up-Regulation | 2014 |
Detection of differentially regulated subsarcolemmal calcium signals activated by vasoactive agonists in rat pulmonary artery smooth muscle cells.
Topics: Angiotensin II; Animals; Biosensing Techniques; Calcium Signaling; Calcium-Binding Proteins; Cell Nucleus; Cells, Cultured; Cytoplasm; Endothelin-1; Excitation Contraction Coupling; Fluorescence Resonance Energy Transfer; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Microscopy, Confocal; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nucleoplasmins; Platelet-Derived Growth Factor; Pulmonary Artery; Rats; Rats, Wistar; Recombinant Fusion Proteins; Sarcolemma; Transfection; Vasoconstriction; Vasoconstrictor Agents | 2014 |
Addition of ET(A) receptor blockade increases renoprotection provided by renin-angiotensin system blockade in 5/6 nephrectomized Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Endothelin Receptor Antagonists; Endothelin-1; Kidney; Kidney Diseases; Nephrectomy; Protective Agents; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Endothelin A; Renin; Renin-Angiotensin System; Systole | 2014 |
Aqueous extract of dioscorea opposita thunb. normalizes the hypertension in 2K1C hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; China; Dioscorea; Drugs, Chinese Herbal; Endothelin-1; Heart; Hypertension; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Kidney; Male; Malondialdehyde; Oxidative Stress; Phytotherapy; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase | 2014 |
Induction of microRNA-138 by pro-inflammatory cytokines causes endothelial cell dysfunction.
Topics: Angiotensin II; Cardiovascular Diseases; Cell Line; Endothelial Cells; Endothelin-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; MAP Kinase Signaling System; MicroRNAs; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase Type III; Phosphorylation; Protein Processing, Post-Translational; S100 Proteins; Transcriptional Activation; Tumor Necrosis Factor-alpha | 2014 |
Effects of renal sympathetic denervation using saline-irrigated radiofrequency ablation catheter on the activity of the renin-angiotensin system and endothelin-1.
Topics: Angiography; Angiotensin II; Animals; Blood Pressure; Catheter Ablation; Denervation; Dogs; Endothelin-1; Female; Kidney; Male; Renin; Renin-Angiotensin System; Sodium Chloride; Sympathectomy; Systole | 2014 |
Effects of moderate strength cold air exposure on blood pressure and biochemical indicators among cardiovascular and cerebrovascular patients.
Topics: Adult; Aged; Air; Angiotensin II; Biomarkers; Blood Pressure; Cardiovascular Diseases; Case-Control Studies; Catecholamines; Cerebrovascular Disorders; Cold Temperature; Endothelin-1; Female; Humans; Male; Middle Aged; Myoglobin; Troponin I | 2014 |
Serine carboxypeptidase SCPEP1 and Cathepsin A play complementary roles in regulation of vasoconstriction via inactivation of endothelin-1.
Topics: Angiotensin II; Animals; Blood Pressure; Carboxypeptidases; Cathepsin A; Cells, Cultured; Endothelin-1; Hemodynamics; Humans; Hypertension; Mice; Vasoconstriction | 2014 |
Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries.
Topics: Aging; Angiotensin II; Animals; Area Under Curve; Carotid Artery, Common; Endothelin-1; Gene Expression Regulation; In Vitro Techniques; Male; Mice, Inbred C57BL; NADPH Oxidases; Receptors, Endothelin; Receptors, Thromboxane; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2014 |
The ameliorating effects of long-term electroacupuncture on cardiovascular remodeling in spontaneously hypertensive rats.
Topics: Acupuncture Points; Angiotensin II; Animals; Aorta; Blood Pressure; Cardiomegaly; Collagen; Electroacupuncture; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Hypertension; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Vascular Remodeling | 2014 |
Pioglitazone reduces angiotensin II-induced COX-2 expression through inhibition of ROS production and ET-1 transcription in vascular cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Cyclooxygenase 2; Endothelin-1; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Thiazolidinediones; Transcription, Genetic | 2014 |
Enhanced expression of Gqα and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1.
Topics: Angiotensin II; Animals; Cells, Cultured; Disease Models, Animal; Endothelin-1; Extracellular Signal-Regulated MAP Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Hypertension; Hypertrophy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Phospholipase C beta; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; RNA Interference; Signal Transduction; Transcription Factor AP-1; Transfection; Up-Regulation | 2014 |
Cardiomyocyte cytokinesis score: a potential method for cardiomyocyte proliferation.
Topics: Angiotensin II; Animals; Cell Line; Cell Proliferation; Cell Size; Cytokinesis; Endothelin-1; Gene Expression; Histones; Ki-67 Antigen; Myocytes, Cardiac; Rats | 2014 |
Beneficial effects of houttuynin on ventricular remodeling induced by coronary artery ligation in rats.
Topics: Aldehydes; Aldosterone; Angiotensin I; Angiotensin II; Animals; Catalase; Collagen; Coronary Vessels; Endothelin-1; Glutathione Peroxidase; Ligation; Male; Myocardium; Rats, Sprague-Dawley; Ventricular Remodeling | 2014 |
Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Line; Endothelin-1; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Up-Regulation; Vasoconstriction | 2014 |
Endothelin-1, but not angiotensin II, induces afferent arteriolar myosin diphosphorylation as a potential contributor to prolonged vasoconstriction.
Topics: Angiotensin II; Animals; Arterioles; Calcium Channel Blockers; Calcium Signaling; Diltiazem; Endothelin A Receptor Antagonists; Endothelin-1; Models, Cardiovascular; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2015 |
Immunological and hemostasiological disorders in women with ovarian hyperstimulation syndrome.
Topics: Adult; Aldosterone; Angiotensin II; Ceruloplasmin; Endothelin-1; Female; Haptoglobins; Homeostasis; Humans; Hydrocortisone; Interleukins; Ovarian Hyperstimulation Syndrome; Pregnancy; Prospective Studies; Renin-Angiotensin System; Statistics, Nonparametric; Tumor Necrosis Factor-alpha | 2014 |
Obligatory role of intraluminal O2- in acute endothelin-1 and angiotensin II signaling to mediate endothelial dysfunction and MAPK activation in guinea-pig hearts.
Topics: Angiotensin II; Animals; Cytoplasm; Endothelin-1; Endothelium, Vascular; Guinea Pigs; Heart; Mitochondria; Mitogen-Activated Protein Kinase 1; Myocardium; NADPH Oxidases; Oxidative Stress; Oxygen Consumption; Phosphorylation; Protein Kinase C; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2014 |
Endothelial MRTF-A mediates angiotensin II induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line; Disease Models, Animal; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Epigenesis, Genetic; Fibrosis; Gene Expression Regulation; Humans; Mice; Models, Biological; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Trans-Activators; Transcriptional Activation | 2015 |
Effects of angiotensin II, atrial natriuretic peptide and endothelin-1 on proliferation and steroidogenic output of bovine granulosa cells cultured in a chemically defined system.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Cattle; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Endothelin-1; Female; Granulosa Cells; Steroids | 2015 |
Modulation of Calcium Signaling of Angiotensin AT1, Endothelin ETA, and ETB Receptors by Silibinin, Quercetin, Crocin, Diallyl Sulfides, and Ginsenoside Rb1.
Topics: Allyl Compounds; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Calcium Signaling; Carotenoids; CHO Cells; Cricetinae; Cricetulus; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Ginsenosides; Humans; Quercetin; Receptors, Angiotensin; Receptors, Endothelin; Silybin; Silymarin; Sulfides | 2015 |
Defining uremic arterial functional abnormalities in patients recently started on haemodialysis: combined in vivo and ex vivo assessment.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Aged; Angiotensin II; Arteries; Bradykinin; Endothelin-1; Female; Humans; Kidney; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; Myography; Nitroprusside; Norepinephrine; Pulse Wave Analysis; Renal Dialysis; Uremia; Vasoconstrictor Agents; Vasopressins | 2014 |
Protective effects of diltiazem against vascular endothelial cell injury induced by angiotensin-II and hypoxia.
Topics: Angiotensin II; Animals; Apoptosis; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Cytoprotection; Diltiazem; Disease Models, Animal; Endothelial Cells; Endothelin-1; Humans; Hypoxia; Male; Membrane Potential, Mitochondrial; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Vascular Diseases | 2015 |
The regulation of connective tissue growth factor expression influences the viability of human trabecular meshwork cells.
Topics: Adult; Aged; Angiotensin II; Blotting, Western; Cell Survival; Cells, Cultured; Connective Tissue Growth Factor; Crystallins; Endothelin-1; Extracellular Matrix; Gene Expression Regulation; Hot Temperature; Humans; Hydrogen Peroxide; Insulin-Like Growth Factor I; Microscopy, Fluorescence; Microtubule-Associated Proteins; Middle Aged; Oxidants; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Trabecular Meshwork | 2015 |
A crosstalk between chromatin remodeling and histone H3K4 methyltransferase complexes in endothelial cells regulates angiotensin II-induced cardiac hypertrophy.
Topics: Angiotensin II; Animals; Cardiomegaly; Cell Line, Transformed; Chromatin Assembly and Disassembly; Disease Models, Animal; DNA Helicases; Endothelial Cells; Endothelin-1; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Male; Mice; Nuclear Proteins; Promoter Regions, Genetic; Protein Binding; Signal Transduction; Trans-Activators; Transcription Factors | 2015 |
Characterization and functions of vascular adventitial fibroblast subpopulations.
Topics: Adventitia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Thoracic; Cell Lineage; Cell Movement; Cell Proliferation; Cells, Cultured; Collagen Type I; Endothelin-1; Fibroblasts; Imidazoles; Losartan; Male; Pyridines; Rats; RNA, Messenger | 2015 |
Beneficial Effects of Renal Denervation on Pulmonary Vascular Remodeling in Experimental Pulmonary Artery Hypertension.
Topics: Angiotensin II; Animals; Collagen; Dimethylformamide; Dinoprostone; Dogs; Echocardiography; Electrocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Female; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Kidney; Lung; Male; Monocrotaline; Neurotransmitter Agents; Random Allocation; Renal Artery; Renin-Angiotensin System; Sympathectomy; Vascular Remodeling | 2015 |
Histone Methyltransferase SET1 Mediates Angiotensin II-Induced Endothelin-1 Transcription and Cardiac Hypertrophy in Mice.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Endothelin-1; Epigenomics; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Mice; Myocytes, Cardiac | 2015 |
Pulmonary vascular and airway responses to systemic vasoconstrictors in anesthetized BALB/c mice.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Airway Resistance; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Endothelin-1; Mice; Mice, Inbred BALB C; Pulmonary Circulation; Thromboxane A2; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasopressins | 2015 |
'Fine-tuning' blood flow to the exercising muscle with advancing age: an update.
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin II; Endothelin-1; Endothelium, Vascular; Exercise; Humans; Muscle Contraction; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide; Receptors, Adrenergic, alpha; Regional Blood Flow; Signal Transduction; Sympathetic Nervous System | 2015 |
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic Stroke.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Corpus Striatum; Diminazene; Disease Models, Animal; Endothelin-1; Enzyme Activation; Imidazoles; Infarction, Middle Cerebral Artery; Infusions, Intraventricular; Leucine; Male; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2015 |
Elevated Endothelial Hypoxia-Inducible Factor-1α Contributes to Glomerular Injury and Promotes Hypertensive Chronic Kidney Disease.
Topics: Angiotensin II; Animals; Antigens, CD; Cadherins; Cells, Cultured; Disease Progression; Endothelial Cells; Endothelin-1; Endothelium, Vascular; Feedback, Physiological; Fibrosis; Gene Expression Regulation; Humans; Hypertension; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Glomerulus; Mice; Mice, Transgenic; NF-kappa B; Organ Culture Techniques; Renal Insufficiency, Chronic; RNA, Small Interfering; Up-Regulation | 2015 |
[Beneficial effects of renal denervation on pulmonary vascular remodeling in experimental pulmonary artery hypertension].
Topics: Angiotensin II; Animals; Blood Pressure; Denervation; Dogs; Echocardiography; Endothelin-1; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Kidney; Lung; Monocrotaline; Pulmonary Artery; Sympathectomy; Vascular Remodeling | 2015 |
The effect of angoroside C on pressure overload-induced ventricular remodeling in rats.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Captopril; Collagen; Constriction, Pathologic; Coumaric Acids; Disease Models, Animal; Endothelin-1; Heart; Heart Rate; Hydroxyproline; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Scrophularia; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Trisaccharides; Ventricular Remodeling | 2015 |
Systemic vasoconstriction modulates the responses of pulmonary vasculature and airway to vasoconstrictors in anesthetized rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Animals; Blood Pressure; Bronchoconstriction; Endothelin-1; Lung; Male; Phenylephrine; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins | 2015 |
Paracrine Signaling in Glial-Like Type II Cells of the Rat Carotid Body.
Topics: Acetylcholine; Adenosine Triphosphate; Angiotensin II; Animals; Calcium; Carotid Body; Cells, Cultured; Endothelin-1; Neuroglia; Paracrine Communication; Rats; Receptor, Angiotensin, Type 1 | 2015 |
Dimethylarginine dimethylaminohydrolase-1 mediates inhibitory effect of interleukin-10 on angiotensin II-induced hypertensive effects in vascular smooth muscle cells of spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Blotting, Western; Cell Proliferation; Cells, Cultured; Endothelin-1; Gene Expression; Hypertension; Interleukin-10; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats, Inbred SHR; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Vasoconstrictor Agents | 2016 |
Sex-Specific Effect of Endothelin in the Blood Pressure Response to Acute Angiotensin II in Growth-Restricted Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Blood Pressure; Blotting, Western; Enalapril; Endothelin Receptor Antagonists; Endothelin-1; Female; Fetal Growth Retardation; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Ovariectomy; Pregnancy; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors | 2015 |
Nebivolol Ameliorates Cisplatin-Induced Nephrotoxicity in Rats.
Topics: Adrenergic beta-1 Receptor Agonists; Angiotensin II; Animals; Antineoplastic Agents; Cisplatin; Creatinine; Endothelin-1; Kidney; Kidney Function Tests; Male; Nebivolol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Urea | 2016 |
Influence of decompression sickness on vasocontraction of isolated rat vessels.
Topics: Angiotensin II; Animals; Antioxidants; Aorta; Decompression Sickness; Diving; Endothelin-1; Endothelium, Vascular; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Thiobarbituric Acid Reactive Substances; Vasoconstriction; Vasodilation | 2016 |
Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs.
Topics: Angiotensin II; Animals; Cyclic CMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Endothelin-1; Hypertension; Loop of Henle; Male; Nitric Oxide; Nitric Oxide Donors; Phosphodiesterase 5 Inhibitors; Rats; Rats, Sprague-Dawley; Solute Carrier Family 12, Member 1; Vardenafil Dihydrochloride | 2016 |
Endothelial actions of atrial natriuretic peptide prevent pulmonary hypertension in mice.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelial Cells; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, Atrial Natriuretic Factor | 2016 |
IMPACT OF RISK FACTOR FOR ATHEROSCLEROSIS ON MICROVASCULAR ENDOTHELIAL FUNCTION: AN IN VITRO STUDY.
Topics: Angiotensin II; Atherosclerosis; Blood Glucose; Cell Line; Cholesterol, LDL; Endothelin-1; Endothelium, Vascular; Healthy Volunteers; Humans; Interleukin-6; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III | 2015 |
The chemokine (C-C motif) ligand protein synthesis inhibitor bindarit prevents cytoskeletal rearrangement and contraction of human mesangial cells.
Topics: Actins; Angiotensin II; Anti-Inflammatory Agents; Cells, Cultured; Chemokines; Cytoskeleton; Endothelin-1; Glomerular Mesangium; Humans; Indazoles; Ligands; Mesangial Cells; Propionates; Protein Synthesis Inhibitors; Transforming Growth Factor beta; Up-Regulation | 2016 |
ESTROGEN RELATED MECHANISMS OF HYPERTENSION IN MENOPAUSAL WOMEN.
Topics: Adult; Angiotensin II; Case-Control Studies; Endothelin-1; Estradiol; Estrogens; Female; Hemoglobins; Humans; Hypertension; Menopause; Middle Aged; Nitric Oxide | 2016 |
Gene silencing of endothelial von Willebrand Factor attenuates angiotensin II-induced endothelin-1 expression in porcine aortic endothelial cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Endothelial Cells; Endothelin-1; Gene Silencing; Swine; von Willebrand Factor | 2016 |
[Intervention of systolic pressure and left ventricular hypertrophy in rats under cold stress].
Topics: Angiotensin II; Animals; Benzazepines; Blood Pressure; Cold Temperature; Endothelin-1; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardium; Rats; Rats, Inbred SHR; Stress, Physiological | 2016 |
Role of dynorphin in hypoxic pulmonary hypertension.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Angiotensin II; Animals; Blood Pressure; Cell Hypoxia; Cell Proliferation; Dynorphins; Endothelin-1; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Lung; Male; Myocytes, Smooth Muscle; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2016 |
Hydrogen sulfide suppresses angiotensin II-stimulated endothelin-1 generation and subsequent cytotoxicity-induced endoplasmic reticulum stress in endothelial cells via NF-κB.
Topics: Angiotensin II; Apoptosis; Cell Survival; Cystathionine gamma-Lyase; Endoplasmic Reticulum Stress; Endothelial Cells; Endothelin-1; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Sulfide; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation | 2016 |
Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats.
Topics: Actins; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cell Proliferation; Collagen Type I; Endothelin-1; Fibroblasts; Male; Malondialdehyde; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Plant Extracts; Rats, Inbred SHR; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Salvia miltiorrhiza; Smad7 Protein; Superoxide Dismutase; Systole; Transforming Growth Factor beta1; Vascular Remodeling; Water | 2016 |
Prostanoids counterbalance the synergism between endothelin-1 and angiotensin II in mesenteric veins of trained rats.
Topics: Angiotensin II; Animals; Endothelin-1; Femoral Vein; Gene Expression Regulation; Imidazoles; Indomethacin; Mesenteric Veins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Culture Techniques; Physical Conditioning, Animal; Prostaglandins; Pyridines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Vasoconstriction | 2017 |
Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient.
Topics: Active Transport, Cell Nucleus; Angiotensin II; Aniline Compounds; Animals; Atrial Remodeling; Calcium; Cardiomegaly; Cytoplasm; Disease Models, Animal; Endothelin-1; Fluorescent Dyes; Gene Expression Regulation; Heterocyclic Compounds, 3-Ring; Humans; Membrane Proteins; Muscular Dystrophy, Emery-Dreifuss; Myocardium; Myocytes, Cardiac; Nuclear Envelope; Nuclear Proteins; Phenylephrine; Primary Cell Culture; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Ventricular Remodeling; Xanthenes | 2017 |
Integrated Treatment of Prostaglandin E1 and Angiotensin-Converting Enzyme Inhibitor in Diabetic Kidney Disease Rats: Possible Role of Antiapoptosis in Renal Tubular Epithelial Cells.
Topics: Alprostadil; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Endothelin-1; Epithelial Cells; Kidney Tubules; Macrophages; Male; Nephritis, Interstitial; Rats, Wistar | 2018 |
Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion.
Topics: Angiotensin II; Animals; Blood Pressure; Carbachol; Endothelin-1; Hypertension; Infarction, Middle Cerebral Artery; Male; Middle Cerebral Artery; Potassium; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation; Viper Venoms | 2018 |
Sulfatase 1 mediates the attenuation of Ang II-induced hypertensive effects by CCL5 in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amidohydrolases; Angiotensin II; Animals; Antihypertensive Agents; Arachidonate 12-Lipoxygenase; Chemokine CCL5; Down-Regulation; Endothelin-1; Hypertension; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sulfotransferases; Up-Regulation | 2018 |
Influence of Sanao Tang on urine volume and expression of aquaporin 2 in rats with respiratory function impairment induced by passive\
smoking and lipopolysaccharide.
Topics: Angiotensin II; Animals; Aquaporin 2; Dinoprostone; Drugs, Chinese Herbal; Endothelin-1; Humans; Lipopolysaccharides; Lung; Lung Diseases; Male; Nicotiana; Rats; Rats, Wistar; Tobacco Smoke Pollution; Urination; Vasopressins | 2016 |
Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog.
Topics: Allosteric Site; Amino Acid Sequence; Angiotensin II; Crystallography, X-Ray; Endothelin-1; Humans; Immunoglobulin Fragments; Kinetics; Ligands; Models, Molecular; Protein Conformation; Receptor, Angiotensin, Type 2; Signal Transduction; Static Electricity | 2018 |
[Effects of Scrophulariae Radix and Split Component on Isoproterenol-Induced Ventricular Remodeling in Rat].
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelin-1; Isoproterenol; Myocardium; Plant Roots; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2016 |
Sulfatase 2 mediates, partially, the expression of endothelin-1 and the additive effect of Ang II-induced endothelin-1 expression by CXCL8 in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Down-Regulation; Endothelin-1; Interleukin-8; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Sulfotransferases | 2019 |
Impact of high-fat diet on vasoconstrictor reactivity of white and brown adipose tissue resistance arteries.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Angiotensin II; Animals; Arteries; Diet, High-Fat; Dietary Fats; Endothelin-1; Male; Mice; Norepinephrine; Vasoconstriction; Vasoconstrictor Agents | 2019 |
Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness.
Topics: Angiotensin II; Animals; Cerebral Arteries; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Losartan; Male; Mice; Muscle, Skeletal; Norepinephrine; Receptor, Angiotensin, Type 1; Vascular Stiffness; Vasoconstriction; Vasoconstrictor Agents | 2019 |
A novel role for myeloid endothelin-B receptors in hypertension.
Topics: Angiotensin II; Animals; Disease Models, Animal; Endocytosis; Endothelin-1; Humans; Hypertension; Macrophages; Mice; Receptor, Endothelin A; Receptor, Endothelin B | 2019 |
Number and brightness analysis to study spatio-temporal distribution of the angiotensin II AT
Topics: Angiotensin II; Animals; Binding Sites; CHO Cells; Cricetulus; Endothelin-1; Fluorescence Resonance Energy Transfer; Humans; Isoxazoles; Ligands; Losartan; Peptides, Cyclic; Protein Aggregates; Receptor, Endothelin A; Thiophenes | 2019 |
Endothelial Forkhead Box Transcription Factor P1 Regulates Pathological Cardiac Remodeling Through Transforming Growth Factor-β1-Endothelin-1 Signal Pathway.
Topics: Angiotensin II; Animals; Aorta; Disease Models, Animal; Endothelin-1; Endothelium, Vascular; Fibrosis; Forkhead Transcription Factors; Heart Failure; Humans; Mice; Mice, Knockout; Myocardium; Nanotubes, Peptide; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor beta1; Ventricular Remodeling | 2019 |
Chronic central miR-29b antagonism alleviates angiotensin II-induced hypertension and vascular endothelial dysfunction.
Topics: Adipokines; Angiotensin II; Animals; Blood Pressure; Cell Movement; Cell Proliferation; Down-Regulation; Endothelial Cells; Endothelin-1; Hypertension; L-Lactate Dehydrogenase; Male; MicroRNAs; Nitric Oxide; Phosphorylation; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2019 |
Ligustrazine prevents basilar artery remodeling in two-kidney-two-clip renovascular hypertension rats via suppressing PI3K/Akt signaling.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelin-1; Hypertension, Renovascular; Ligation; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Pyrazines; Rats, Sprague-Dawley; Renal Artery; Signal Transduction; Temporal Arteries; Vascular Remodeling | 2020 |
MiR-21, MiR-29a, GATA4, and MEF2c Expression Changes in Endothelin-1 and Angiotensin II Cardiac Hypertrophy Stimulated Isl-1
Topics: Angiotensin II; Animals; Antigens, Surface; Biomarkers; Cardiomegaly; Cells, Cultured; Cellular Reprogramming; Connexin 43; Disease Susceptibility; Endothelin-1; GATA4 Transcription Factor; Genetic Predisposition to Disease; Immunophenotyping; MEF2 Transcription Factors; MicroRNAs; Myoblasts, Cardiac; Phenotype; Swine; Ventricular Remodeling | 2019 |
Effect of an aqueous extract of Averrhoa carambola L. on endothelial function in rats with ventricular remodelling.
Topics: Angiotensin II; Animals; Averrhoa; Endothelin-1; Endothelium, Vascular; Female; Male; Myocardium; Nitric Oxide Synthase; Plant Extracts; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta; Ventricular Remodeling | 2020 |
Comparison of Vascular Responses to Vasoconstrictors in Human Placenta in Preeclampsia between Preterm and Later Term.
Topics: Angiotensin II; Arteries; Endothelin-1; Female; Humans; In Vitro Techniques; Infant, Newborn; Microvessels; Placenta; Pre-Eclampsia; Pregnancy; Premature Birth; Serotonin; Term Birth; Vasoconstriction; Vasoconstrictor Agents | 2020 |
Mechanisms of Metabolic Acidosis-Induced Kidney Injury in Chronic Kidney Disease.
Topics: Acid-Base Equilibrium; Acidosis; Adaptation, Physiological; Aldosterone; Angiotensin II; Biomarkers; Disease Progression; Endothelin-1; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Prospective Studies; Renal Insufficiency, Chronic; Retrospective Studies; Risk Assessment; Severity of Illness Index; Time Factors; Treatment Outcome | 2020 |
Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Captopril; Drug Therapy, Combination; Drugs, Chinese Herbal; Endothelin-1; Gene Expression Regulation; Hypertension; Kidney Diseases; Lipid Metabolism; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Inbred SHR | 2020 |
Mandibular Advancement Devices Prevent the Adverse Cardiac Effects of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS).
Topics: Acrylic Resins; Angiotensin II; Animals; Cytokines; Echocardiography; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Heart; Male; Myocardium; Occlusal Splints; Polysomnography; Rabbits; RNA, Messenger; Sleep Apnea, Obstructive; Ventricular Dysfunction, Left | 2020 |
Effect of
Topics: Acacia; Angiotensin II; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endothelin-1; Glucose; Glycated Hemoglobin; Gum Arabic; Insulins; Kidney; Male; Rats; Rats, Sprague-Dawley; Senegal; Transforming Growth Factor beta1 | 2022 |
Angiotensin converting enzyme inhibitor potentiates the hypoglycaemic effect of NG-nitro-L-arginine methyl ester (L-NAME) in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Blood Pressure; Endothelin-1; Enzyme Inhibitors; Hypertension; Hypoglycemic Agents; Insulins; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Prostaglandins I; Ramipril; Rats; Rats, Wistar | 2022 |
Angiotensin II Induces Increased Myocardial Expression of Receptor for Advanced Glycation End Products, Monocyte/Macrophage Infiltration and Circulating Endothelin-1 in Rats With Experimental Diabetes.
Topics: Angiotensin II; Animals; Diabetes Mellitus, Experimental; Endothelin-1; Glycation End Products, Advanced; Macrophages; Male; Monocytes; Myocardium; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Vasoconstrictor Agents | 2020 |
Antihypertensive properties of a traditional Chinese medicine GAO-ZI-YAO in elderly spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Cytokines; Drugs, Chinese Herbal; Endothelin-1; Hypertension; Irbesartan; Male; Medicine, Chinese Traditional; Nitric Oxide; Rats; Rats, Inbred SHR; Vascular Endothelial Growth Factor A | 2020 |
Collecting duct cells show differential retinoic acid responses to acute versus chronic kidney injury stimuli.
Topics: Acetylcholine; Albumins; Aldosterone; Angiotensin II; Animals; Calcitonin Gene-Related Peptide; Cell Line; Cisplatin; Endothelin-1; Female; Glucose; Humans; Kidney Diseases; Kidney Tubules, Collecting; Lipopolysaccharides; Mice; Mice, Transgenic; Receptors, Retinoic Acid; Tretinoin; Vasopressins | 2020 |
P2Y11 Agonism Prevents Hypoxia/Reoxygenation- and Angiotensin II-Induced Vascular Dysfunction and Intimal Hyperplasia Development.
Topics: Angiotensin II; Animals; Aorta; Diphosphonates; Endothelin-1; Human Umbilical Vein Endothelial Cells; Humans; Hyperplasia; Male; Myocytes, Smooth Muscle; Naphthalenesulfonates; Nitric Oxide; Nitric Oxide Synthase Type III; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Reperfusion Injury; Tunica Intima; Vasodilation; Water | 2021 |
Adaptation to 5 weeks of intermittent local vascular pressure increments; mechanisms to be considered in the development of primary hypertension?
Topics: Adaptation, Physiological; Adult; Angiotensin II; Arm; Arterial Pressure; Endothelin-1; Humans; Hypertension; Male; Matrix Metalloproteinase 7; Regional Blood Flow; Time Factors; Vascular Remodeling; Vascular Stiffness; Young Adult | 2021 |
A Flounder Fish Peptide Shows Anti-Hypertensive Effects by Suppressing the Renin-Angiotensin-Aldosterone System and Endothelin-1.
Topics: Administration, Oral; Aldosterone; Amino Acid Sequence; AMP-Activated Protein Kinases; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Endothelin-1; Fish Proteins; Flounder; Gene Expression Regulation; Hypertension; Kidney; Male; Muscles; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction | 2021 |
Evaluation of Propofol in Inhibiting Proliferation of Cardiac Fibroblasts in Angiotensin II-Induced Mouse.
Topics: Angiotensin II; Animals; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Fibroblasts; Fibronectins; Mice; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Propofol; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Specific Pathogen-Free Organisms | 2021 |
Testosterone attenuates hypoxia-induced hypertension by affecting NRF1-mediated transcriptional regulation of ET-1 and ACE.
Topics: Angiotensin II; Animals; Endothelial Cells; Endothelin-1; Hypertension; Hypoxia; Nuclear Respiratory Factor 1; Peptidyl-Dipeptidase A; Rats; Testosterone | 2021 |
Blocking of interleukin-1 suppresses angiotensin II-induced renal injury.
Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Bosentan; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypertension; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction | 2021 |
Reducing Proteoglycan Synthesis and NOX Activity by ROCK Inhibitors: Therapeutic Targets in Atherosclerosis.
Topics: Angiotensin II; Atherosclerosis; Endothelin-1; Humans; Hypertension; Protein Serine-Threonine Kinases; Proteoglycans; Receptors, G-Protein-Coupled; rho-Associated Kinases; Serine | 2022 |
Renin-Angiotensin and Endothelin Systems in Patients Post-Takotsubo Cardiomyopathy.
Topics: Angiotensin II; Endothelin-1; Humans; Renin; Stroke Volume; Takotsubo Cardiomyopathy; Ventricular Function, Left | 2022 |
Levels of angiotensin II type-1 receptor antibodies and endothelin-1 type-A receptor antibodies correlate with antibody-mediated rejection and poor graft function in kidney-transplantation patients.
Topics: Angiotensin II; Antibodies; Endothelin-1; Female; Graft Rejection; HLA Antigens; Humans; Kidney; Kidney Transplantation; Receptor, Angiotensin, Type 1; Receptor, Endothelin A | 2022 |
Purification identification and function analysis of ACE inhibitory peptide from Ulva prolifera protein.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelial Cells; Endothelin-1; Humans; Hydrolysis; Lipopolysaccharides; Mice; Molecular Docking Simulation; Nitric Oxide Synthase Type III; Papain; Pepsin A; Peptide Hydrolases; Peptides; Peptidyl-Dipeptidase A; Protein Hydrolysates; Subtilisins; Trypsin; Ulva | 2023 |
Endothelin type A receptor blockade attenuates aorto-caval fistula-induced heart failure in rats with angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrasentan; Endothelin-1; Endothelins; Fistula; Heart Failure; Hypertension; Rats; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptor, Endothelin A | 2023 |
Development of non-bias phenotypic drug screening for cardiomyocyte hypertrophy by image segmentation using deep learning.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Cholesterol; Deep Learning; Drug Evaluation, Preclinical; Endothelin-1; Ezetimibe; Heart Failure; Mice; Myocytes, Cardiac; Rats | 2022 |
Autoimmune activation and hypersensitization of the AT1 and ETA receptors contributes to vascular injury in scleroderma renal crisis.
Topics: Acute Kidney Injury; Angiotensin II; Animals; Autoantibodies; Endothelin-1; Immunoglobulin G; Rats; Receptor, Endothelin A; Scleroderma, Localized; Vascular System Injuries | 2023 |