angiotensin ii has been researched along with elastin in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.30) | 18.7374 |
| 1990's | 3 (3.90) | 18.2507 |
| 2000's | 9 (11.69) | 29.6817 |
| 2010's | 51 (66.23) | 24.3611 |
| 2020's | 13 (16.88) | 2.80 |
| Authors | Studies |
|---|---|
| Uchiyama, T | 1 |
| Armentano, RL; Barra, JG; Breitbart, GJ; Fischer, EI; Levenson, J; Pichel, RH; Simon, A | 1 |
| Kato, H; Tajima, S; Tokimitsu, I; Wachi, H | 1 |
| Benessiano, J; Caputo, L; Duriez, M; Henrion, D; Heymes, C; Levy, BI; Poitevin, P; Samuel, JL | 1 |
| Banbula, A; Kordula, T; Macomson, J; Travis, J | 1 |
| Athanassious, CN; Da Cunha, V; Martin-McNulty, B; Powers, AF; Rutledge, JC; Sullivan, ME; Tham, DM; Wang, YX; Wilson, DW | 1 |
| Cassis, LA; Daugherty, A; Lodder, RA; Manning, MW; Urbas, A | 1 |
| Amiri, F; Endemann, D; Neves, MF; Pu, Q; Rozen, R; Schiffrin, EL; Virdis, A | 1 |
| Amiri, F; Brassard, P; Schiffrin, EL | 1 |
| Bai, A; Bianchi, R; Cuccovillo, I; De Angelis, N; Doni, M; Fiordaliso, F; Ghezzi, P; Latini, R; Masson, S; Salio, M | 1 |
| Carretero, OA; D'Ambrosio, MA; Liao, TD; Lin, CX; Rhaleb, NE; Yang, XP | 1 |
| Aikawa, E; Aikawa, M; Deguchi, JO; Huang, H; Lee, RT; Libby, P; Sylvan, J; Whittaker, P | 1 |
| Higuchi, T; Horikoshi, H; Hosono, Y; Matsumoto, M; Nakanishi, T; Nakayama, M; Ohsuzu, F; Okada, M; Suzuki, K; Takada, K | 1 |
| Danpinid, A; Konofagou, EE; Luo, J; Terdtoon, P; Vappou, J | 1 |
| Barr, KN; Choi, G; Connolly, AJ; Dalman, RL; Eastham-Anderson, JR; Goergen, CJ; Greve, JM; Hedehus, M; Huynh, DT; Taylor, CA; Tsao, PS | 1 |
| Azuma, J; Barr, KN; Connolly, AJ; Dalman, RL; Goergen, CJ; Gogineni, A; Greve, JM; Grewall, A; Kallop, DY; Magdefessel, L; Taylor, CA; Tsao, PS; Weimer, RM | 1 |
| Bruemmer, D; Cohn, D; Daugherty, A; Findeisen, HM; Gizard, F; Heywood, EB; Howatt, DA; Jones, KL; Lovett, DH; Zhao, Y | 1 |
| Fukuda, D; Libby, P; Rocha, VZ; Shi, GP; Shimizu, K; Shvartz, E; Sukhova, G; Tang, EH; Zheng, C | 1 |
| Gleason, RL; Joseph, G; Maiellaro-Rafferty, K; Taylor, WR; Wan, W; Weiss, D | 1 |
| Dietz, HC; Lindsay, ME | 1 |
| Antonioli, L; Aydinoglu, F; Bernardini, N; Blandizzi, C; Colucci, R; Duranti, E; Fornai, M; Ippolito, C; Neves, MF; Rugani, I; Solini, A; Taddei, S; Virdis, A | 1 |
| Bricca, G; Dab, H; Dhaouadi, N; Hachani, R; Hodroj, W; Kacem, K; Randon, J; Sakly, M | 2 |
| Goldstein, R; Green, D; Hill, N; Polgar, P; Rich, C; Stone, P; Taylor, L; Toselli, P; Warburton, R; Yu, J | 1 |
| Azuma, J; Chin, JT; Dalman, RL; Deng, A; Leeper, NJ; Maegdefessel, L; McConnell, MV; Merk, DR; Raaz, U; Raiesdana, A; Schoelmerich, AM; Spin, JM; Toh, R; Tsao, PS | 1 |
| Bustelo, XR; Campuzano, V; Coustets, M; Francke, U; Menacho-Márquez, M; Nevado, J; Pérez-Jurado, LA; Sánchez-Rodríguez, C; Segura-Puimedon, M; Terrado, V | 1 |
| Cau, SB; Ceron, CS; Gerlach, RF; Guimaraes, DA; Martins-Oliveira, A; Ramos, J; Rizzi, E; Tanus-Santos, JE | 1 |
| Chen, H; Liu, L; Shi, GP; Shi, MA; Sukhova, GK; Sun, J; Zhang, J | 1 |
| Cao, X; Du, J; Guo, J; Li, H; Pan, L; Qin, Y; Shi, GP; Tang, C; Zhang, H; Zhang, Y | 1 |
| Basu, R; Davidge, ST; Fan, D; Kandalam, V; Kassiri, Z; Lee, J; Morton, JS; Takawale, A; Wang, X | 1 |
| Abello, N; Deckert, V; Desrumaux, C; Gautier, T; Habbout, A; Kretz, B; Labbé, J; Lagrost, L; Le Guern, N; Lemaire-Ewing, S; Maquart, G; Masson, D; Raghay, K; Steinmetz, E | 1 |
| Fu, XM; Narita, Y; Oshima, H; Ueda, Y; Usui, A; Yamawaki-Ogata, A | 1 |
| Clancy, P; Golledge, J; Koblar, SA; Seto, SW | 1 |
| Givvimani, S; Kundu, S; Lederer, E; Pryor, T; Pushpakumar, S; Sen, U; Tyagi, SC | 1 |
| Chang, WC; Chen, JW; Huang, PH; Leu, HB; Lin, SJ; Peng, YJ; Tsai, HY; Tsai, SH | 1 |
| Chen, W; Harrison, DG; Kirabo, A; Madhur, MS; Saleh, MA; Thabet, SR; Trott, DW; Wu, J; Xiao, L | 1 |
| Blumer, KJ; Dietrich, HH; Knutsen, RH; Kozel, BA; Mecham, RP; Osei-Owusu, P | 1 |
| Airey, D; F Linton, M; Fazio, S; Hill, MF; Kon, V; Nwosu, S; Perati, PR; Prins, PA; Sampson, UK; Tavori, H | 1 |
| Cheng, J; Garg, V; Hans, CP; Koenig, SN; Kuivaniemi, HS | 1 |
| Balakrishnan, A; Cassis, LA; Daugherty, A; Davis, FM; Fornwalt, BK; Haggerty, CM; Howatt, DA; Muratoglu, SC; Rateri, DL; Strickland, DK | 1 |
| Biros, E; Clancy, P; Golledge, J; Jose, RJ; Krishna, SM; Moran, CS; Seto, SW; Wang, Y | 1 |
| Basu, R; Fan, D; Kassiri, Z; Lee, J; Sakamuri, SS; Shen, M; Wang, X | 1 |
| Bailey, W; Balakrishnan, A; Charnigo, RJ; Daugherty, A; De Beer, FC; De Beer, MC; Howatt, DA; Ji, A; Noffsinger, VP; Rateri, DL; Shridas, P; Webb, NR; Witta, J; Wroblewski, JM | 1 |
| Chan, CT; Diep, H; Drummond, GR; Guzik, TJ; Kemp-Harper, BK; Krishnan, SM; Lieu, M; Moore, JP; Ricardo, SD; Sakkal, S; Samuel, CS; Sobey, CG; Tare, M; Tuck, KL; Vinh, A | 1 |
| Al-Omran, M; Dhingra, N; Leong-Poi, H; Lovren, F; Quan, A; Ramadan, A; Singh, KK; Teoh, H; Verma, S; Wheatcroft, MD | 1 |
| Eriksson, P; Lundberg, AM; Mäyränpää, MI; Vorkapic, E; Wågsäter, D | 1 |
| Chang, BI; Cheng, MH; Cheng, TL; Hsu, YY; Lai, CH; Li, YH; Luo, CY; Ma, CY; Shi, GY; Tsai, HW; Wang, KC; Wu, HL | 1 |
| Akiki, R; Bachschmid, M; Cohen, RA; Fry, JL; Gao, YZ; Morgan, KG; Seta, F; Shiraishi, Y; Turcotte, R; Yu, X; Zhang, Y | 1 |
| Atkins, GB; Dong, N; Gerson, SL; Golledge, J; Hiraoka, S; Kuivaniemi, H; Lin, Z; Moxon, JV; Norman, P; Perbal, B; Prosdocimo, DA; Qing, Y; Rittié, L; Shi, GP; Shi, H; Takemoto, M; van der Voort, D; Yokote, K; Zhang, C; Zhang, R | 1 |
| Aguiló, S; Camacho, M; Dilmé, J; Galán, M; Martínez-González, J; Orriols, M; Rodriguez, C; Rodríguez, JA; Varona, S | 1 |
| Chang, AY; Chen, JY; Jiang, MJ; Lai, CH; Li, YH; Lin, SC; Maeda, N; Tai, HC; Teng, SH; Tsai, PJ; Tsai, YS; Wang, KC; Wu, HL | 1 |
| Anagnostopoulou, A; Antunes, TT; Callera, GE; Dulak-Lis, MG; He, Y; Jaisser, F; Montezano, AC; Nguyen Dinh Cat, A; Sanchez, A; Touyz, RM; Tsiropoulou, S | 1 |
| Chen, H; Liu, D; Liu, Y; Wang, F; Yan, Y; Zhang, S | 1 |
| Chen, HZ; Gao, P; Liu, DP; Pei, JF; She, ZG; Wang, F; Wang, TT; Yan, YF; Zhang, R; Zhang, Y; Zhang, ZQ | 1 |
| Li, X; Liu, X; Tian, Y; Wang, J; Wu, J; Yu, X | 1 |
| Clancy, P; Crossman, DJ; Emeto, TI; Golledge, J; Jose, R; Krishna, SM; Li, J; Moxon, J; Norman, P; Seto, SW | 1 |
| Chang, BI; Cheng, TL; Kuo, CH; Lai, CH; Lee, FT; Shi, GY; Wang, KC; Wu, HL; Yang, YJ | 1 |
| Chai, H; Chen, W; Chen, X; Huang, F; Su, C; Tao, Z; Xu, Y | 1 |
| Daugherty, A; Gong, MC; Guo, Z; Hou, T; Liu, S; Lu, H; Lutshumba, J; Zhong, Y | 1 |
| Duan, J; Guo, J; Jou, D; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Lv, J; Ma, H; Shi, W; Tao, J; Wang, Y; Yan, D; Zhai, M; Zhang, C | 1 |
| Abe, T; Lee Fujimoto, K; Mutsuga, M; Narita, Y; Oshima, H; Tokuda, Y; Uchida, W; Usui, A; Yamawaki-Ogata, A | 1 |
| Anqi, S; Baoli, Z; Biao, X; Fu, C; Jianzhou, C; Jiaxin, H; Jin, G; Jinxuan, Z; Jun, X; Lian, Z; Shuaihua, Q; Xiwen, Z; Xueling, L | 1 |
| Chuma, M; Fujino, H; Fukushima, K; Horinouchi, Y; Ikeda, Y; Imanishi, M; Ishizawa, K; Izawa-Ishizawa, Y; Kohara, Y; Sairyo, E; Sakurada, T; Takechi, K; Tamaki, T; Tsuchiya, K; Yoshizumi, M; Zamami, Y | 1 |
| Adams, LC; Botnar, RM; Brangsch, J; Buchholz, R; Hamm, B; Karst, U; Kaufmann, JO; Makowski, MR; Onthank, DC; Reimann, C; Robinson, SP; Thöne-Reineke, C | 1 |
| Grochot-Przęczek, A; Hajduk, K; Józkowicz, A; Klóska, D; Kopacz, A; Neumayer, C; Piechota-Polanczyk, A; Werner, E | 1 |
| Alonso, J; Ballester-Servera, C; Briones, AM; Cañes, L; Martí-Pàmies, I; Martínez-González, J; Rodríguez, C; Serrano, E | 1 |
| Humphrey, JD; Kawamura, Y; Murtada, SI; Weiss, D | 1 |
| Cui, M; Fu, X; Liang, K; Ma, J; Zhai, S; Zhang, D; Zhang, K | 1 |
| Dhital, S; Eberth, JF; Hasanain, S; Lane, BA; Lessner, SM; Nosoudi, N; Parasaram, V; Vyavahare, NR; Wang, X | 1 |
| Becares, M; Bermeo, H; Briones, AM; García-Redondo, AB; González-Amor, M; Guerra, S; Jorge, I; Martínez-González, J; Montezano, AC; Redondo, JM; Rios, FJ; Rodrigues-Díez, R; Rodríguez, C; Ruiz-Rodríguez, MJ; Salaices, M; Touyz, RM; Vázquez, J; Zalba, G | 1 |
| Asada, Y; Chosa, E; Funamoto, T; Hatakeyama, K; Kato, J; Kitamura, K; Koide, M; Nakamichi, Y; Otsu, M; Sekita-Hatakeyama, Y; Tsuruda, T; Udagawa, N; Yamashita, A | 1 |
| Idrees, M; Khalid, M; Manzoor, S | 1 |
| Alebrahim, D; Attur, M; Byrd, D; Harpel, Z; Lu, C; Maldonado, DJ; Mignatti, P; Pratama, MY; Ramkhelawon, B; Rivera, CF; Silvestro, M; Sleiman Tellaoui, R; Tang, C; Vlahos, J; Zias, AL | 1 |
| Dohgu, S; Inada, K; Koga, M; Yamada, A; Yamauchi, A | 1 |
| De Meyer, GRY; De Moudt, S; Fransen, P; Hendrickx, JO; Martinet, W | 1 |
| Chen, D; Gao, S; Ge, S; Luo, J; Niu, K; Ren, M; Shao, Y; Wang, X; Wu, Q; Xiao, Q; Yang, M; Yang, Z; Zhang, C; Zhou, X | 1 |
| Chen, CY; Chen, JS; Chen, JW; Huang, PH; Lin, CP; Lin, SJ; Tzeng, IS; Wu, MY | 1 |
2 review(s) available for angiotensin ii and elastin
| Article | Year |
|---|---|
[Biochemical basis of lung function in health and disease (author's transl)].
Topics: Amines; Angiotensin II; Animals; Bradykinin; Connective Tissue; Elastin; Glucose; Humans; Lung; Lung Diseases; Phospholipids; Procollagen; Prostaglandins; Proteins; Pulmonary Alveolar Proteinosis; Pulmonary Surfactants; Rats | 1978 |
Lessons on the pathogenesis of aneurysm from heritable conditions.
Topics: Angiotensin II; Animals; Aortic Aneurysm; Disease Models, Animal; Elastin; Humans; Muscle, Smooth, Vascular; Transforming Growth Factor beta | 2011 |
75 other study(ies) available for angiotensin ii and elastin
| Article | Year |
|---|---|
Assessment of elastin and collagen contribution to aortic elasticity in conscious dogs.
Topics: Angiotensin II; Animals; Aorta; Collagen; Consciousness; Dogs; Elasticity; Elastin; Hemodynamics; Injections, Intravenous; Male; Nitroglycerin | 1991 |
Elastin synthesis is inhibited by angiotensin II but not by platelet-derived growth factor in arterial smooth muscle cells.
Topics: Angiotensin II; Animals; Cell Division; Cells, Cultured; Chick Embryo; Collagen; Elastin; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor | 1994 |
Chronic blockade of AT2-subtype receptors prevents the effect of angiotensin II on the rat vascular structure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Hypertrophy; Imidazoles; Infusions, Parenteral; Losartan; Male; Muscle, Smooth, Vascular; Phenylephrine; Pyridines; Rats; Rats, Wistar; Reference Values; Tetrazoles | 1996 |
Isolation and properties of stachyrase A, a chymotrypsin-like serine proteinase from Stachybotrys chartarum.
Topics: alpha 1-Antichymotrypsin; alpha-Macroglobulins; Angiotensin I; Angiotensin II; Binding Sites; Bradykinin; Chymotrypsin; Collagen; Elastin; Neurotensin; Serine Endopeptidases; Serine Proteinase Inhibitors; Stachybotrys; Substance P; Tosylphenylalanyl Chloromethyl Ketone | 2002 |
Angiotensin II injures the arterial wall causing increased aortic stiffening in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Arteriosclerosis; Blood Pressure; Carotid Arteries; Collagen; Drug Administration Schedule; Elasticity; Elastin; Endothelium, Vascular; Male; Mice; Mice, Knockout; Nitroprusside | 2002 |
Near-infrared spectrometry of abdominal aortic aneurysm in the ApoE-/- mouse.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Calibration; Collagen; Elastin; Mice; Mice, Inbred C57BL; Mice, Knockout; Reverse Transcriptase Polymerase Chain Reaction; Spectroscopy, Near-Infrared | 2003 |
Small artery mechanics in hyperhomocysteinemic mice: effects of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Collagen; Disease Models, Animal; Elastin; Female; Homocysteine; Hyperhomocysteinemia; Male; Mesenteric Arteries; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Mice, Knockout; Vasoconstrictor Agents | 2004 |
Combined angiotensin II type 1 and type 2 receptor blockade on vascular remodeling and matrix metalloproteinases in resistance arteries.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Collagen Type I; Elasticity; Elastin; Fibronectins; Hydralazine; Losartan; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance | 2005 |
Cardiovascular oxidative stress is reduced by an ACE inhibitor in a rat model of streptozotocin-induced diabetes.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Body Weight; Cardiovascular System; Diabetes Mellitus, Experimental; Drinking; Elastin; Extracellular Space; Fibrosis; Heart Ventricles; Hemodynamics; Male; Myocardium; Myocytes, Cardiac; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides | 2006 |
Prevention of aortic fibrosis by N-acetyl-seryl-aspartyl-lysyl-proline in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Aorta; Collagen; Elastin; Enzyme Activation; Fibrosis; Heart Diseases; Hypertension; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lipid Metabolism; Male; Neutrophil Infiltration; Oligopeptides; Oxidation-Reduction; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Smad2 Protein; Transforming Growth Factor beta1; Vasoconstrictor Agents | 2008 |
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Collagen; Collagenases; Connective Tissue; Elastin; Histocytochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2009 |
Effects of angiotensin on the expression of fibrosis-associated cytokines, growth factors, and matrix proteins in human lung fibroblasts.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Collagen; Cytokines; Elastin; Extracellular Matrix Proteins; Fibroblasts; Gene Expression Regulation; Humans; Intercellular Signaling Peptides and Proteins; Lung; Microscopy, Confocal; RNA, Messenger; Tetrazoles | 2009 |
In vivo characterization of the aortic wall stress-strain relationship.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Collagen; Elasticity; Elastin; Mice; Models, Cardiovascular; Stress, Mechanical; Ultrasonography | 2010 |
In vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growth.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Elastin; Genotype; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motion; Time Factors | 2010 |
Influences of aortic motion and curvature on vessel expansion in murine experimental aneurysms.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena; Blood Pressure; Disease Progression; Elastin; Hypertension; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Models, Cardiovascular; Ultrasonography | 2011 |
Telomerase deficiency in bone marrow-derived cells attenuates angiotensin II-induced abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Transplantation; Cell Movement; Cells, Cultured; Elastin; Genotype; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Models, Animal; Receptors, LDL; Telomerase; Telomere | 2011 |
Deletion of EP4 on bone marrow-derived cells enhances inflammation and angiotensin II-induced abdominal aortic aneurysm formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Bone Marrow Cells; Bone Marrow Transplantation; Chemokine CCL2; Elastin; Female; Gene Deletion; Hyperlipidemias; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Receptors, LDL; Receptors, Prostaglandin E, EP4 Subtype; Risk Factors | 2011 |
Catalase overexpression in aortic smooth muscle prevents pathological mechanical changes underlying abdominal aortic aneurysm formation.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomechanical Phenomena; Blood Pressure; Catalase; Collagen; Disease Models, Animal; Elastin; Hydrogen Peroxide; Mice; Mice, Knockout; Mice, Transgenic; Stress, Mechanical; Time Factors; Up-Regulation | 2011 |
Resistance artery mechanics and composition in angiotensin II-infused mice: effects of cyclooxygenase-1 inhibition.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Angiotensin II; Animals; Biomechanical Phenomena; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Cells, Cultured; Collagen Type I; Coronary Vessels; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprost; Elastin; Fatty Acids, Unsaturated; Fibronectins; Humans; Hydrazines; Immunohistochemistry; Male; Mesenteric Arteries; Mice; Mice, Knockout; Pyrazoles; Vascular Resistance | 2012 |
Physiological regulation of extracellular matrix collagen and elastin in the arterial wall of rats by noradrenergic tone and angiotensin II.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Blood Pressure; Blotting, Western; Body Weight; Collagen; Collagen Type I; Collagen Type III; Elastin; Extracellular Matrix; Femoral Artery; Gene Expression Regulation; Male; Models, Biological; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Rats; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction | 2012 |
Transgenic expression of an altered angiotensin type I AT1 receptor resulting in marked modulation of vascular type I collagen.
Topics: Angiotensin II; Animals; Aorta; Arachidonic Acid; Bradykinin; Cells, Cultured; Collagen Type I; Elastin; Enzyme Activation; GTP-Binding Protein alpha Subunits, Gi-Go; Mice; Mice, Transgenic; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Protein Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Signal Transduction; Transgenes | 2012 |
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
Topics: Adolescent; Aged; Aneurysm, Ruptured; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Disease Progression; Elastin; Gene Expression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Middle Aged; Pancreatic Elastase; Protein Isoforms; Swine; Young Adult | 2012 |
Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.
Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Pressure; Cardiomegaly; Constriction, Pathologic; Disease Models, Animal; Elastin; Enzyme Activation; Enzyme Inhibitors; Humans; Hypertension; Losartan; Mice; NADPH Oxidases; Oxidative Stress; Sequence Deletion; Williams Syndrome | 2012 |
Time course involvement of matrix metalloproteinases in the vascular alterations of renovascular hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Collagen; Elastin; Enzyme Activation; Fluorescent Antibody Technique; Hypertension, Renovascular; Immunohistochemistry; Male; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; NADPH Oxidases; Oxidative Stress; Protease Inhibitors; Rats; Rats, Wistar; Reactive Oxygen Species; Renal Artery; Time Factors; Tissue Inhibitor of Metalloproteinase-2 | 2012 |
Regulation of aortic extracellular matrix synthesis via noradrenergic system and angiotensin II in juvenile rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Collagen Type I; Collagen Type II; Collagen Type III; Elastin; Extracellular Matrix; Guanethidine; Losartan; Male; Rats; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathectomy; Sympathetic Nervous System | 2012 |
Chemokine (C-C motif) receptor 2 mediates mast cell migration to abdominal aortic aneurysm lesions in mice.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cell Proliferation; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Proto-Oncogene Proteins c-kit; Receptors, CCR2 | 2012 |
Deficiency of cathepsin S attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Apoptosis; Cathepsin K; Cathepsins; CD3 Complex; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; T-Lymphocytes; Time Factors | 2012 |
TIMP3 is the primary TIMP to regulate agonist-induced vascular remodelling and hypertension.
Topics: Angiotensin II; Animals; Arterial Pressure; Carotid Arteries; Collagen; Disease Models, Animal; Elastin; Gelatinases; Hypertension; Matrix Metalloproteinase Inhibitors; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Time Factors; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Vasoconstriction; Vasodilation | 2013 |
Development of abdominal aortic aneurysm is decreased in mice with plasma phospholipid transfer protein deficiency.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; CD4-Positive T-Lymphocytes; Cytokines; Elastin; Inflammation; Liver; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatic Elastase; Phospholipid Transfer Proteins | 2013 |
Intravenous administration of mesenchymal stem cells prevents angiotensin II-induced aortic aneurysm formation in apolipoprotein E-deficient mouse.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Apolipoproteins E; Bone Marrow Cells; Cytokines; Disease Progression; Elastin; Femur; Inflammation; Injections, Intravenous; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout | 2013 |
Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Carotid Artery Diseases; Collagenases; Dipeptides; Elastin; Endarterectomy, Carotid; Extracellular Matrix; Humans; Irbesartan; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Matrix Metalloproteinase Inhibitors; Organ Culture Techniques; Peptides; Peptidyl-Dipeptidase A; Plaque, Atherosclerotic; Quinapril; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrahydroisoquinolines; Tetrazoles | 2013 |
Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice.
Topics: Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Collagen; Elastin; Hypertension; Kidney; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases | 2013 |
Zoledronate attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of Rho/ROCK-dependent JNK and NF-κB pathway.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Adhesion; Cell Line; Coculture Techniques; Dilatation, Pathologic; Diphosphonates; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelial Cells; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; NF-kappa B; Phosphorylation; Receptors, LDL; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Vascular Cell Adhesion Molecule-1; Zoledronic Acid | 2013 |
Inflammation and mechanical stretch promote aortic stiffening in hypertension through activation of p38 mitogen-activated protein kinase.
Topics: Adoptive Transfer; Angiotensin II; Animals; Aortic Diseases; CD4 Antigens; CD8 Antigens; Cells, Cultured; Collagen; Disease Models, Animal; Elastin; Fibroblasts; Homeodomain Proteins; Hypertension; Inflammation; Interleukin-17; Male; Mice; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Stress, Mechanical; T-Lymphocytes; Vascular Stiffness; Vasculitis; Vasoconstrictor Agents | 2014 |
Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency.
Topics: Angiotensin II; Animals; Arterial Pressure; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Elastin; Endothelium, Vascular; Genetic Predisposition to Disease; Haploinsufficiency; Hemizygote; Hypertension; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; rho-Associated Kinases; Signal Transduction; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2014 |
Angiotensin-induced abdominal aortic aneurysms in hypercholesterolemic mice: role of serum cholesterol and temporal effects of exposure.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cholesterol; Elastin; Hypercholesterolemia; Macrophages; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Time Factors; Ultrasonography | 2014 |
Pharmacological inhibitor of notch signaling stabilizes the progression of small abdominal aortic aneurysm in a mouse model.
Topics: Aged; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Cell Differentiation; Cells, Cultured; Collagen; Dipeptides; Disease Models, Animal; Disease Progression; Elastin; Gene Expression Regulation; Humans; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout; Middle Aged; Receptor, Notch1; Signal Transduction; Time Factors; Transforming Growth Factor beta2 | 2014 |
Smooth muscle cell deletion of low-density lipoprotein receptor-related protein 1 augments angiotensin II-induced superior mesenteric arterial and ascending aortic aneurysms.
Topics: Aneurysm; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Arterial Pressure; Cells, Cultured; Dilatation, Pathologic; Disease Models, Animal; Elastin; Gene Deletion; Ligands; Low Density Lipoprotein Receptor-Related Protein-1; Macrophages; Male; Matrix Metalloproteinase 2; Mesenteric Artery, Superior; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Norepinephrine; Receptors, LDL; RNA, Messenger; Tumor Suppressor Proteins; Urokinase-Type Plasminogen Activator | 2015 |
A peptide antagonist of thrombospondin-1 promotes abdominal aortic aneurysm progression in the angiotensin II-infused apolipoprotein-E-deficient mouse.
Topics: Amino Acid Oxidoreductases; Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins E; Atherosclerosis; Cytokines; Disease Models, Animal; Disease Progression; Elastin; Inflammation Mediators; Injections, Intraperitoneal; Male; Mice, Knockout; Peptides; Phosphorylation; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Smad2 Protein; Smad3 Protein; Thrombospondin 1; Time Factors; Transforming Growth Factor beta1 | 2015 |
Divergent roles of matrix metalloproteinase 2 in pathogenesis of thoracic aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Calcium Chloride; Cells, Cultured; Collagen; Dilatation, Pathologic; Disease Models, Animal; Elastin; Genotype; Male; Matrix Metalloproteinase 2; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; RNA, Messenger; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Ultrasonography; Vascular Remodeling | 2015 |
Deficiency of Endogenous Acute-Phase Serum Amyloid A Protects apoE-/- Mice From Angiotensin II-Induced Abdominal Aortic Aneurysm Formation.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Disease Models, Animal; Elastin; Macrophages; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Mice, Knockout; Random Allocation; Sensitivity and Specificity; Serum Amyloid A Protein | 2015 |
M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure.
Topics: Angiotensin II; Animals; Antigens, CD; Antigens, Ly; Aorta; Arginase; Blood Pressure; Collagen; Elastin; Fibrosis; Hypertension; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Receptors, CCR2 | 2015 |
Effects of long-term chloroquine administration on the natural history of aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Autophagy; Chloroquine; Collagen; Disease Models, Animal; Disease Progression; Elastin; Male; Mice, Inbred C57BL; Mice, Knockout; Time Factors | 2015 |
TRIF adaptor signaling is important in abdominal aortic aneurysm formation.
Topics: Adaptor Proteins, Vesicular Transport; Angiotensin II; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aorta; Aortic Aneurysm, Abdominal; Apolipoproteins; Apolipoproteins E; CD3 Complex; Elastin; Gene Expression Regulation; Humans; Inflammation; Mice; Mice, Knockout; Signal Transduction; Toll-Like Receptors | 2015 |
Membrane-Bound Thrombomodulin Regulates Macrophage Inflammation in Abdominal Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortitis; Calcium Chloride; Cell Membrane; Cells, Cultured; Chemotaxis; Disease Models, Animal; Elastin; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Macrophages, Peritoneal; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Retrospective Studies; RNA Interference; Signal Transduction; Thrombomodulin; Time Factors; Transfection | 2015 |
Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Aortic Aneurysm; Aortic Dissection; Cells, Cultured; Cyclic N-Oxides; Disease Models, Animal; Elastic Tissue; Elastin; Free Radical Scavengers; Hypertension; Matrix Metalloproteinases; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Sirtuin 1; Spin Labels; Time Factors | 2015 |
Matricellular protein CCN3 mitigates abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Gene Deletion; Humans; MAP Kinase Signaling System; Mice; Mice, Knockout; Nephroblastoma Overexpressed Protein; Pancreatic Elastase | 2016 |
Induction of histone deacetylases (HDACs) in human abdominal aortic aneurysm: therapeutic potential of HDAC inhibitors.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Collagen; Disease Models, Animal; Disease Progression; Elastin; Enzyme Induction; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Inflammation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Severity of Illness Index; Up-Regulation | 2016 |
Peroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cells, Cultured; Disease Models, Animal; Elastin; Gene Expression Regulation; Humans; Inflammation; Male; Matrix Metalloproteinases; Mice; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; PPAR gamma | 2016 |
Adipocyte-Specific Mineralocorticoid Receptor Overexpression in Mice Is Associated With Metabolic Syndrome and Vascular Dysfunction: Role of Redox-Sensitive PKG-1 and Rho Kinase.
Topics: Adipocytes; Aldosterone; Angiotensin II; Animals; Cells, Cultured; Corticosterone; Culture Media, Conditioned; Elastin; Humans; Intra-Abdominal Fat; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Oxidation-Reduction; Phosphorylation; Receptors, Mineralocorticoid; rho-Associated Kinases | 2016 |
Baicalein protects against the development of angiotensin II-induced abdominal aortic aneurysms by blocking JNK and p38 MAPK signaling.
Topics: Angiotensin II; Animals; Antioxidants; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blotting, Western; Elastin; Flavanones; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Protective Agents; Reactive Oxygen Species; Receptor, Angiotensin, Type 1 | 2016 |
The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Aryldialkylphosphatase; Cells, Cultured; Disease Models, Animal; Elastin; Extracellular Matrix; Genetic Predisposition to Disease; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Multigene Family; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxidative Stress; Phenotype; Proteolysis; Reactive Oxygen Species; Signal Transduction | 2017 |
MicroRNA-145 Mediates the Formation of Angiotensin II-Induced Murine Abdominal Aortic Aneurysm.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Collagen; Disease Models, Animal; Elastin; Gene Expression Regulation, Enzymologic; Lentivirus; Matrix Metalloproteinase 2; Mice; Mice, Knockout; MicroRNAs; Transduction, Genetic; Up-Regulation | 2017 |
High serum thrombospondin-1 concentration is associated with slower abdominal aortic aneurysm growth and deficiency of thrombospondin-1 promotes angiotensin II induced aortic aneurysm in mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; Biomarkers; Cells, Cultured; Collagen Type III; Disease Models, Animal; Disease Progression; Elastin; Genetic Predisposition to Disease; Humans; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 9; Mice, Knockout; Odds Ratio; Phenotype; Proteolysis; Receptors, LDL; Risk Factors; Thrombospondin 1; Time Factors; Tumor Suppressor Proteins; Ultrasonography; Vascular Remodeling | 2017 |
Recombinant adeno-associated virus vector carrying the thrombomodulin lectin-like domain for the treatment of abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Calcium Chloride; Cytokines; Dependovirus; Disease Models, Animal; Elastin; Genetic Therapy; Genetic Vectors; HMGB1 Protein; Macrophages; Male; Matrix Metalloproteinases; Mice, Knockout, ApoE; Oxidative Stress; Protein Domains; Receptor for Advanced Glycation End Products; Thrombomodulin; Vascular Remodeling | 2017 |
Cortistatin attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of the ERK1/2 signaling pathways.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Cell Line; Disease Models, Animal; Elastin; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout, ApoE; Myocytes, Smooth Muscle; Neuropeptides; Proteolysis; Reactive Oxygen Species | 2018 |
Deletion of BMAL1 in Smooth Muscle Cells Protects Mice From Abdominal Aortic Aneurysms.
Topics: Aldosterone; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; ARNTL Transcription Factors; Binding Sites; Desoxycorticosterone Acetate; Dilatation, Pathologic; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Sodium Chloride, Dietary; Tissue Inhibitor of Metalloproteinase-4; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic | 2018 |
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
Topics: ADAM17 Protein; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Line; Cell Proliferation; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Vascular Remodeling; Wound Healing | 2018 |
The oral administration of clarithromycin prevents the progression and rupture of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Rupture; Cells, Cultured; Clarithromycin; Disease Models, Animal; Elastin; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Macrophages; Male; Matrix Metalloproteinases, Secreted; Mice, Inbred C57BL; Mice, Knockout, ApoE; NF-kappa B; Phosphorylation; Vascular Remodeling | 2018 |
PM2.5 promotes abdominal aortic aneurysm formation in angiotensin Ⅱ-infused apoe-/- mice.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apolipoproteins E; beta-Galactosidase; Biomarkers; Cell Line; Chemokine CCL2; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Elastin; Humans; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Particulate Matter; Reactive Oxygen Species | 2018 |
Nitrosonifedipine, a Photodegradation Product of Nifedipine, Suppresses Pharmacologically Induced Aortic Aneurysm Formation.
Topics: Aminopropionitrile; Angiotensin II; Animals; Antigens, Differentiation; Antioxidants; Aortic Aneurysm; Chemokine CCL2; Cyclophilins; Disease Models, Animal; Elastin; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Matrix Metalloproteinase 2; Mice; Nifedipine; Nitroso Compounds; Oxidative Stress; Photolysis; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2018 |
Concurrent Molecular Magnetic Resonance Imaging of Inflammatory Activity and Extracellular Matrix Degradation for the Prediction of Aneurysm Rupture.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Aortic Rupture; Contrast Media; Disease Models, Animal; Disease Progression; Elastin; Extracellular Matrix; Feasibility Studies; Ferrosoferric Oxide; Gadolinium DTPA; Inflammation Mediators; Magnetic Resonance Imaging; Male; Mice, Knockout, ApoE; Molecular Imaging; Predictive Value of Tests; Reproducibility of Results; Time Factors | 2019 |
Simvastatin Attenuates Abdominal Aortic Aneurysm Formation Favoured by Lack of Nrf2 Transcriptional Activity.
Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm, Abdominal; Blood Pressure; Collagen; Elastin; Humans; Inflammation; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; Simvastatin; Transcription, Genetic; Vascular Cell Adhesion Molecule-1 | 2020 |
High NOR-1 (Neuron-Derived Orphan Receptor 1) Expression Strengthens the Vascular Wall Response to Angiotensin II Leading to Aneurysm Formation in Mice.
Topics: Aneurysm; Angiotensin II; Animals; Disease Models, Animal; DNA-Binding Proteins; Elastin; Inflammation; Matrix Metalloproteinases; Mice; Mice, Transgenic; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nerve Tissue Proteins; Oxidative Stress; Receptors, Steroid; Receptors, Thyroid Hormone; Signal Transduction | 2021 |
Differential biomechanical responses of elastic and muscular arteries to angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Arteries; Elastin; Hypertension; Mesenteric Arteries; Mice; Pulse Wave Analysis | 2021 |
LncRNA Xist induces arterial smooth muscle cell apoptosis in thoracic aortic aneurysm through miR-29b-3p/Eln pathway.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Line; Elastin; Humans; Mice; MicroRNAs; Muscle, Smooth, Vascular; Rats; RNA, Long Noncoding; Signal Transduction | 2021 |
Systemic delivery of targeted nanotherapeutic reverses angiotensin II-induced abdominal aortic aneurysms in mice.
Topics: Angiotensin II; Animals; Antibodies; Aortic Aneurysm, Abdominal; Drug Delivery Systems; Elastin; Hydrolyzable Tannins; Injections, Intravenous; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Serum Albumin, Bovine | 2021 |
Interferon-stimulated gene 15 pathway is a novel mediator of endothelial dysfunction and aneurysms development in angiotensin II infused mice through increased oxidative stress.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Carotid Intima-Media Thickness; Elastin; Humans; Hypertension; Inflammation; Interferons; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species | 2022 |
Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin-Deficient Mice.
Topics: Angiotensin II; Animals; Aortic Dissection; Aortic Rupture; Disease Models, Animal; Elastin; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteoprotegerin; RANK Ligand | 2022 |
P2X4 receptors mediate induction of antioxidants, fibrogenic cytokines and ECM transcripts; in presence of replicating HCV in in vitro setting: An insight into role of P2X4 in fibrosis.
Topics: Angiotensin II; Animals; Antioxidants; Carcinoma, Hepatocellular; Cytokines; Elastin; Fibrosis; Hepacivirus; Hepatitis C; Humans; Laminin; Liver Neoplasms; Rats; Receptors, Purinergic P2X4; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2022 |
The Nonproteolytic Intracellular Domain of Membrane-Type 1 Matrix Metalloproteinase Coordinately Modulates Abdominal Aortic Aneurysm and Atherosclerosis in Mice-Brief Report.
Topics: Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Atherosclerosis; Cholesterol; Elastin; Matrix Metalloproteinase 14; Mice; Netrin-1; Proprotein Convertase 9; Subtilisins | 2022 |
Moxifloxacin induces aortic aneurysm and dissection by increasing osteopontin in mice.
Topics: Angiotensin II; Animals; Anti-Bacterial Agents; Aortic Aneurysm; Aortic Dissection; Disease Models, Animal; Elastin; Eosine Yellowish-(YS); Hematoxylin; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Moxifloxacin; Muscle Proteins; Myocytes, Smooth Muscle; Osteopontin; Rubber; Water | 2022 |
Disparate biomechanical properties of the aorta in non-aneurysmal and aneurysmal mice treated with angiotensin II.
Topics: Adrenergic Agents; Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Collagen; Elastin; Mice; Mice, Inbred C57BL; Pulse Wave Analysis | 2022 |
Targeted Inhibition of Matrix Metalloproteinase-8 Prevents Aortic Dissection in a Murine Model.
Topics: Aminopropionitrile; Angiotensin II; Animals; Aortic Dissection; Disease Models, Animal; Elastin; Humans; Inflammation; Matrix Metalloproteinase 8; Mice; Mice, Knockout; Reactive Oxygen Species; Vascular Cell Adhesion Molecule-1 | 2022 |
Tributyrin Intake Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm in
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Elastin; Epigenesis, Genetic; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout | 2023 |