Compounds > angiotensin ii
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angiotensin ii and cyclosporine

angiotensin ii has been researched along with cyclosporine in 81 studies

Research

Studies (81)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's36 (44.44)18.2507
2000's33 (40.74)29.6817
2010's11 (13.58)24.3611
2020's1 (1.23)2.80

Authors

AuthorsStudies
Hardy, KJ; Phillips, PA; Potocnik, SJ1
Callís, L; Fortuny, G; Nieto, J; Vila, A1
Huss, R; Locher, R; Vetter, W1
Grabensee, B; Heering, P; Kreuzpaintner, G; Kutkuhn, B; Reinhard, T; Sundmacher, R1
Bronsther, O; Brown, MR; Crum, R; Dominic, W; Fairchild, R; Fernandez, R; Ward, D1
Bunke, M; Martin, A; Wilder, L1
Berkenboom, G; Brékine, D; Fontaine, J; Gulbis, B; Unger, P1
Auch-Schwelk, W; Duske, E; Fleck, E; Hess, B; Hildebrandt, AG; Klein, U; Regitz-Zagrosek, V; Steffen, C1
Fogo, A; Hunley, TE; Kon, V1
Cambar, J; L'Azou, B; Lakhdar, B; Potier, M1
Andreis, PG; Gottardo, G; Malendowicz, LK; Markowska, A; Mazzocchi, G; Neri, G; Nussdorfer, GG; Tortorella, C1
Aldred, K; Hardy, KJ; Phillips, PA; Rolls, KA1
Ballardie, FW; Chalmers, RJ; Edwards, BD; Lawson, RS; Mitchell, DM; O'Driscoll, JB; Smith, RJ; Testa, HJ1
Conde, M; Gualberto, A; Sobrino, F1
Baumelou, A; Bletry, O; Deray, G; Faucher, C; Godeau, P; Jacobs, C; Rieu, P1
Auch-Schwelk, W; Betz, M; Duske, E; Fleck, E; Hink, U; Unkelbach, M1
Ballardie, FW; Chalmers, RJ; Edwards, BD; Lawson, RS; O'Driscoll, J; Testa, HJ1
Auch-Schwelk, W; Bossaller, C; Fleck, E; Götze, S; Thelen, J1
Clozel, JP; Fischli, W; Ménard, J1
Brown, MR; De Nicola, L; Gabbai, FB; Thomson, SC; Wead, LM1
Bokemeyer, D; Drechsler, S; Friedrichs, U; Kramer, HJ; Meyer-Lehnert, H1
Braith, RW; Davis, GL; Mills, RM; Wilcox, CS; Wood, CE1
Eaton, DC; Ling, BN; Ma, H; Matsunaga, H1
Coutie, WJ; Lang, CC; Struthers, AD; Sturrock, ND1
Alpers, CE; Andoh, TF; Bennett, WM; Burdmann, EA; Couser, WG; Franceschini, N; Hugo, C; Pichler, RH; Shankland, SJ; Young, BA1
Hodge, EE; Inman, SR; Novick, AC; Stowe, NT1
Aparicio, M; Cambar, J; Combe, C; Forpomès, O1
Andoh, TF; Bennett, WM; Shihab, FS; Tanner, AM1
Aguilar, M; Andujar, M; Arrebola, F; del Moral, RG; García-Chicano, MJ; Gómez-Morales, M; Guillén, M; Masseroli, M; Nogales, FF; O'Valle, F; Olmo, A; Ramírez, C1
Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE1
Abbott, KL; Boss, V; Murphy, TJ; Pavlath, GK; Wang, XF1
Aguilar, M; Arrebola, F; Asensio, C; Becerra, P; Carvia, R; Del Moral, RG; Guillén, M; O'Valle, F; Olmo, A; Osuna, A; Reguero, ME1
Afanasjeva, GV; Avdonin, PV; Cottet-Maire, F; Lhote, P; Loktionova, SA; Ruegg, UT1
Woo, KT1
Bieringer, M; Breu, V; Dechend, R; Fiebeler, A; Ganten, D; Haller, H; Luft, FC; Mervaala, E; Müller, DN; Park, JK; Schmidt, F1
Fu, M; Liu, N; Pang, Y; Su, J; Tang, C; Xu, S; Zhang, J1
Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS; Tendron, A1
Brunner, HR; Murat, A; Pedrazzini, T; Pellieux, C1
Grabs, R; Olbrich, HG; Richter, H; Richter, M; Schramm, D; Skupin, M1
Field, MJ; Johnson, DW; Pollock, CA; Qi, W; Saunders, HJ; Vesey, DA1
Fu, MG; Jiang, ZS; Liu, NK; Pang, YZ; Tang, CS; Wang, XH1
Ahn, HJ; Bang, BK; Kim, J; Kim, SK; Kim, WY; Kim, YO; Kim, YS; Park, JH; Shin, MJ; Yang, CW1
Buttrick, PM; Geenen, DL; Goldspink, PH; Kimball, VA; McKinney, RD1
Levi, M; Moons, AH; Peters, RJ1
Kellems, RE; Wen, HY; Xia, Y1
Eguchi, S; Frank, GD; Inagami, T; Motley, ED; Saito, S; Utsunomiya, H1
Andoh, TF; Bennett, WM; Isaac, J; Shihab, FS; Yi, H1
Ahn, HJ; Bang, BK; Cha, JH; Jung, JY; Kim, J; Kim, WY; Kim, YS; Li, C; Yang, CW; Yoon, SA1
Ha, H; Kim, H; Kim, MS; Kim, YS; Lee, JH; Park, J; Park, K; Seo, J1
Ahonen, J; Finckenberg, P; Ganten, D; Inkinen, K; Louhelainen, M; Luft, F; Merasto, S; Mervaala, E; Müller, D; Vapaatalo, H1
Abe, Y; Fukui, T; Hitomi, H; Kimura, S; Kiyomoto, H; Kobori, H; Kohno, M; Nishiyama, A; Rahman, M; Shokoji, T; Yao, L; Zhang, GX1
Bens, M; Chang, CT; Vandewalle, A; Wu, MS; Yang, CW1
Fu, M; Liu, N; Pang, Y; Tang, C; Xu, S; Zhang, J1
Hou, FF; Wang, L; Zhang, GH; Zhang, X1
Fujita, T; Goto, A; Hirata, Y; Nagai, R; Nishimatsu, H; Oba, S; Omata, M; Satonaka, H; Suzuki, E; Takeda, R1
Ahn, KO; Choi, YH; Chung, BH; Ito, S; Kim, J; Li, C; Lim, SW; Sugawara, A; Sun, BK; Yang, CW; Yang, JH; Yoon, KH1
Ahn, KO; Bang, BK; Choi, BS; Kim, J; Kim, JS; Kim, JY; Kim, YS; Li, C; Lim, SW; Yang, CW; Yang, HJ1
Bartoli, E; Bergamasco, L; Castello, L; Letizia, C; Sainaghi, PP2
Han, Z; Xiang, J; Yang, Y; Zhang, K1
Gillin, A; Harris, D; Johnson, D; Nicholls, K; Thomas, M1
Chen, LM; Chu, CH; Huang, CY; Kuo, WW; Lee, SD; Lin, JA; Liu, CJ; Liu, JY; Lu, MC; Wu, CH1
Epting, T; Gordjani, N; Hartmann, K; Nitschke, R; Sandqvist, A1
Cibulskyte, D; Frøkiaer, J; Hansen, HE; Hørlyck, A; Madsen, M; Marcussen, N; Mortensen, J; Pedersen, M1
Ishikawa, A; Kitamura, T; Ohta, N; Ozono, S; Tanaka, M1
Ahn, KO; Ghee, JY; Kim, J; Kim, JY; Kim, SH; Li, C; Lim, SW; Yang, CW; Yang, HJ1
Alba, G; Chacón, P; El Bekay, R; Jiménez, J; Martín-Nieto, J; Oliván, J; Pintado, E; Ramos, E; Reyes, ME; Sobrino, F; Vega, A1
Fan, Y; Shang, MH; Yuan, WJ; Zhang, SJ; Zhang, Z1
Chen, J; Cheng, M; Ding, X; Han, F; Le, Y; Xu, L; Zhang, L; Zhu, X1
Ghee, JY; Han, DH; Kim, S; Kobori, H; Kuro-o, M; Ohashi, N; Piao, S; Song, JH; Yang, CW; Yoon, HE1
Borlak, J; Niehof, M1
Cucchiari, D; Graziani, G; Ponticelli, C1
Cornaire, E; Galichon, P; Hertig, A; Mesnard, L; Rondeau, E; Vandermeersch, S; Vittoz, N; Xu-Dubois, YC1
Arbonés, ML; Campanero, MR; Esteban, V; García-Redondo, AB; Jiménez-Borreguero, LJ; Méndez-Barbero, N; Novensá, L; Redondo, JM; Roqué, M; Salaices, M; Vila, L1
Montezano, AC; Touyz, RM; White, M1
Periasamy, S; Rao, S; Senthilkumar, K; Subramani, T1
Bin, J; Cao, S; Chen, C; Huang, X; Kitakaze, M; Li, G; Li, X; Liao, Y; Shen, L; Xu, D; Xuan, W; Zhang, J1
Huang, X; Lin, Y; Qian, D; Tan, J; Wang, Y; Xia, J; Zhang, X1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R1
Alp-Yıldırım, Fİ; Bekpinar, S; Cibali, E; Gultepe, S; Karaca, E; Olgac, V; Uydes-Doğan, BS; Uysal, M; Yamakoğlu, S1
Bachmann, S; Hu, J; Mutig, K; Xu, Y1

Reviews

4 review(s) available for angiotensin ii and cyclosporine

ArticleYear
Role of growth factors in mesangial cell ion channel regulation.
    Kidney international, 1995, Volume: 48, Issue:4

    Topics: Angiotensin II; Animals; Calcium; Chloride Channels; Cyclosporine; Diabetic Nephropathies; Endothelins; Furosemide; Glomerular Mesangium; Growth Substances; Humans; Insulin; Ion Channels; Ion Transport; Models, Biological; Receptors, Angiotensin

1995
Current therapeutic strategies in glomerulonephritis.
    Annals of the Academy of Medicine, Singapore, 1999, Volume: 28, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Cyclophosphamide; Cyclosporine; Dipyridamole; Glomerulonephritis; Humans; Immunosuppressive Agents; Nephrotic Syndrome; Remission Induction; Steroids; Tacrolimus; Vasodilator Agents; Warfarin

1999
Tissue factor and coronary artery disease.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: Acute Disease; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Anticoagulants; Arginine; Aspirin; Coronary Artery Disease; Coronary Thrombosis; Cyclosporine; Endothelium, Vascular; Factor VIIa; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Hypolipidemic Agents; Leukocytes, Mononuclear; Muscle, Smooth, Vascular; Recombinant Proteins; Thrombin; Thromboplastin

2002
Hypertension in kidney transplant recipients.
    Transplant international : official journal of the European Society for Organ Transplantation, 2011, Volume: 24, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcineurin Inhibitors; Calcium Channel Blockers; Cardiovascular Diseases; Cyclosporine; Diuretics; Glucocorticoids; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Life Style; Renal Artery Obstruction; Vascular Resistance

2011

Trials

3 trial(s) available for angiotensin ii and cyclosporine

ArticleYear
Angiotensin II as a risk factor for cyclosporin nephrotoxicity in patients with psoriasis.
    Clinical nephrology, 1994, Volume: 41, Issue:6

    Topics: Adult; Aged; Angiotensin II; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Psoriasis; Renal Circulation; Renin-Angiotensin System; Risk Factors

1994
Cyclosporin-induced renal vasoconstriction is augmented by frusemide and by angiotensin II in humans.
    Journal of hypertension, 1995, Volume: 13, Issue:9

    Topics: Adult; Angiotensin II; Cross-Over Studies; Cyclosporine; Diuretics; Double-Blind Method; Furosemide; Humans; Hypertension, Renal; Male; Renal Circulation; Renin-Angiotensin System; Vasoconstriction; Vasoconstrictor Agents

1995
Efficacy and safety of losartan in treatment of hyperuricemia and posttransplantation erythrocytosis: results of a prospective, open, randomized, case-control study.
    Transplantation proceedings, 2009, Volume: 41, Issue:9

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Case-Control Studies; Cyclosporine; Female; Humans; Hyperuricemia; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Polycythemia; Prospective Studies; Receptor, Angiotensin, Type 1; Safety; Uric Acid

2009

Other Studies

74 other study(ies) available for angiotensin ii and cyclosporine

ArticleYear
Human resistance artery reactivity is altered by liver transplantation and treatment with cyclosporin A.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Adipose Tissue; Angiotensin II; Arginine Vasopressin; Arteries; Cyclosporine; Humans; In Vitro Techniques; Liver Neoplasms; Liver Transplantation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Vascular Resistance; Vasoconstriction

1992
Effect of cyclosporin A on proteinuria in patients with Alport's syndrome.
    Pediatric nephrology (Berlin, Germany), 1992, Volume: 6, Issue:2

    Topics: Adolescent; Angiotensin II; Basement Membrane; Child; Creatinine; Cyclosporine; Female; Humans; Kidney Function Tests; Kidney Glomerulus; Liver Function Tests; Male; Nephritis, Hereditary; Proteinuria

1992
Potentiation of vascular smooth muscle cell activity by cyclosporin A.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:4

    Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Cyclosporine; DNA; Drug Synergism; Female; Inositol Phosphates; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Thymidine

1991
[Kidney function of patients with healthy kidneys during cyclosporin treatment].
    Klinische Wochenschrift, 1991, Nov-26, Volume: 69, Issue:19

    Topics: Acid-Base Equilibrium; Adult; Aldosterone; Angiotensin II; Corneal Transplantation; Creatinine; Cyclosporine; Female; Humans; Kidney; Kidney Function Tests; Liver Transplantation; Male; Renin; Water-Electrolyte Balance

1991
Neuroendocrinology of chronic renal failure and renal transplantation.
    Transplantation, 1991, Volume: 52, Issue:5

    Topics: Adult; Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Cyclosporine; Epinephrine; Furosemide; Humans; Hypertension, Renal; Kidney Failure, Chronic; Kidney Transplantation; Methylprednisolone; Neurosecretory Systems; Norepinephrine; Prospective Studies; Radioimmunoassay; Renal Dialysis; Water-Electrolyte Balance

1991
The effect of cyclosporine on agonist-stimulated glomerular and mesangial cell vasodilatory prostaglandin production.
    Transplantation, 1991, Volume: 52, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Creatine; Cyclosporine; Dinoprostone; Glomerular Filtration Rate; Glomerular Mesangium; Kidney Glomerulus; Kidney Medulla; Male; Norepinephrine; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Vascular Resistance; Vasodilation; Vasodilator Agents

1991
Attenuation of cyclosporine A-induced vascular toxicity by ramipril.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:1

    Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Blood Pressure; Cyclosporine; Endothelium, Vascular; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Ramipril; Rats; Rats, Wistar

1994
Tissue- and subtype-specific modulation of angiotensin II receptors by chronic treatment with cyclosporin A, angiotensin-converting enzyme inhibitors and AT1 antagonists.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Administration, Oral; Adrenal Cortex; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cyclosporine; Down-Regulation; Drug Interactions; Imidazoles; Kidney; Lisinopril; Liver; Losartan; Male; Pyridines; Quinolines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Up-Regulation

1995
Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Studies in chronic cyclosporine nephrotoxicity in rats.
    Transplantation, 1995, Jul-15, Volume: 60, Issue:1

    Topics: Angiotensin II; Animals; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Fibrosis; Kidney Function Tests; Kidney Glomerulus; Male; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Vasoconstriction

1995
Image analyser as a tool for the study of in vitro glomerular vasoreactivity.
    Cell biology and toxicology, 1994, Volume: 10, Issue:5-6

    Topics: Angiotensin II; Animals; Cell Size; Cells, Cultured; Cyclosporine; Glomerular Mesangium; Image Processing, Computer-Assisted; Kidney Glomerulus; Microscopy, Video; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents; Verapamil

1994
Effects of cyclosporine-A on steroid secretion of dispersed rat adrenocortical cells.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 45, Issue:8

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Cyclosporine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Radioimmunoassay; Rats; Rats, Wistar

1994
Vasoconstrictor responses to components of the renin-angiotensin system in cyclosporin-induced hypertension in the rat.
    Clinical and experimental pharmacology & physiology, 1994, Volume: 21, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cyclosporine; Female; Hypertension; In Vitro Techniques; Mesenteric Arteries; Rats; Rats, Wistar; Renin-Angiotensin System; Sensitivity and Specificity; Vascular Resistance; Vasoconstriction

1994
Cyclosporin A antagonizes phenylephrine, oxytocin and angiotensin effects on glucose metabolism in rat thymus lymphocytes.
    Biochimica et biophysica acta, 1994, Mar-31, Volume: 1221, Issue:2

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Cyclosporine; Dose-Response Relationship, Drug; Fructosediphosphates; Glucose; Glycolysis; Lactates; Lactic Acid; Lymphocytes; Male; Oxytocin; Phenylephrine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland

1994
Medical nephrectomy with CsA and angiotensin II in a case of life-threatening membranous glomerulonephritis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1994, Volume: 9, Issue:1

    Topics: Adult; Angiotensin II; Cyclosporine; Glomerulonephritis, Membranous; Humans; Kidney; Male; Nephrectomy; Nephrotic Syndrome

1994
Vasomotor responses in cyclosporin A-treated rats after chronic angiotensin blockade.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:6 Pt 2

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Cyclosporine; Heart; Heart Rate; Kidney; Lisinopril; Liver; Male; Organ Size; Quinolines; Rats; Rats, Wistar; Time Factors; Vasoconstriction; Vasodilation; Vasomotor System; Weight Gain

1994
Modulation of abnormalities in renal haemodynamics and vasoactive mediators by nifedipine in patients with psoriasis on low-dose cyclosporin.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:10

    Topics: Adolescent; Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Cyclosporine; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hemodynamics; Hormones; Humans; Male; Middle Aged; Nifedipine; Psoriasis; Renal Circulation

1993
Calcium entry blockade may prevent cyclosporin A-induced hypersensitivity to angiotensin II and endothelial dysfunction in the rat aorta.
    European heart journal, 1993, Volume: 14 Suppl I

    Topics: Angiotensin II; Animals; Aorta; Cyclosporine; Diltiazem; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Random Allocation; Rats; Rats, Wistar; Vasodilation

1993
Effects of the blockade of the renin-angiotensin system in cyclosporin-induced hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:1

    Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Cilazapril; Cyclosporine; Female; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Male; Renin; Renin-Angiotensin System; Saimiri

1993
Arginine feeding modifies cyclosporine nephrotoxicity in rats.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Administration, Oral; Angiotensin II; Animals; Arginine; Capillaries; Cyclosporine; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney; Kidney Glomerulus; Male; Nephrons; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance

1993
Cellular signaling by cyclosporine A in contractile cells: interactions with atrial natriuretic peptide.
    The Clinical investigator, 1993, Volume: 71, Issue:2

    Topics: Angiotensin II; Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Calcium; Cells, Cultured; Cyclosporine; Glomerular Mesangium; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Signal Transduction

1993
Breakdown of blood pressure and body fluid homeostasis in heart transplant recipients.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:2

    Topics: Angiotensin II; Arginine Vasopressin; Atrial Natriuretic Factor; Blood Pressure; Case-Control Studies; Cyclosporine; Female; Heart; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Liver Transplantation; Male; Middle Aged; Renin-Angiotensin System; Sodium Chloride; Sodium, Dietary; Ventricular Function, Left; Water-Electrolyte Balance; Water-Electrolyte Imbalance

1996
Pathogenesis of cyclosporine nephropathy: roles of angiotensin II and osteopontin.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 6, Issue:4

    Topics: Angiotensin II; Animals; Blood Pressure; Cyclosporine; Cytokines; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Sialoglycoproteins

1995
Cyclosporine A enhances the vascular reactivity to angiotensin II in the renal microcirculation in rodents.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Angiotensin II; Animals; Arterioles; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Hydronephrosis; Male; Microcirculation; Rats; Rats, Wistar; Renal Circulation; Vasodilation

1996
Cyclosporin-A- and angiotensin-II-induced vasoreactivity in isolated glomeruli and cultured mesangial cells, 4 and 24 h after renal mass reduction: role of vasodilatory prostaglandins.
    Nephron, 1997, Volume: 76, Issue:3

    Topics: Adaptation, Physiological; Angiotensin II; Animals; Cells, Cultured; Cyclosporine; Glomerular Filtration Rate; Glomerular Mesangium; In Vitro Techniques; Indomethacin; Kidney Failure, Chronic; Kidney Glomerulus; Male; Nephrectomy; Prostaglandins; Rats; Rats, Sprague-Dawley; Renal Circulation; Time Factors; Vasoconstriction; Vasodilation

1997
Angiotensin II blockade decreases TGF-beta1 and matrix proteins in cyclosporine nephropathy.
    Kidney international, 1997, Volume: 52, Issue:3

    Topics: Angiotensin II; Animals; Blotting, Northern; Cyclosporine; Extracellular Matrix Proteins; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta

1997
Chronic cyclosporin A nephrotoxicity, P-glycoprotein overexpression, and relationships with intrarenal angiotensin II deposits.
    The American journal of pathology, 1997, Volume: 151, Issue:6

    Topics: Angiotensin II; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Chronic Disease; Creatinine; Cyclosporine; Gene Expression Regulation; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Urea

1997
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
    Kidney international, 1998, Volume: 53, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Arginine; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Fibrosis; Hydralazine; Immunosuppressive Agents; Ischemia; Kidney; Losartan; Macrophages; Male; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Staining and Labeling

1998
The cyclosporin A-sensitive nuclear factor of activated T cells (NFAT) proteins are expressed in vascular smooth muscle cells. Differential localization of NFAT isoforms and induction of NFAT-mediated transcription by phospholipase C-coupled cell surface
    The Journal of biological chemistry, 1998, Jul-31, Volume: 273, Issue:31

    Topics: Angiotensin II; Animals; Becaplermin; Calcium; Cells, Cultured; Colforsin; Cyclosporine; DNA-Binding Proteins; Gene Expression Regulation; Genes, Reporter; GTP-Binding Proteins; Immunohistochemistry; Muscle, Smooth, Vascular; NFATC Transcription Factors; Nuclear Proteins; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thrombin; Transcription Factors; Type C Phospholipases

1998
Role of P-glycoprotein in chronic cyclosporine nephrotoxicity and its relationship to intrarenal angiotensin II deposits.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Angiotensin II; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Creatinine; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Kidney Cortex; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley

1998
Cyclosporine A up-regulates angiotensin II receptors and calcium responses in human vascular smooth muscle cells.
    Kidney international, 1999, Volume: 55, Issue:6

    Topics: Angiotensin II; Calcineurin Inhibitors; Calcium; Cells, Cultured; Cyclosporine; Cytosol; Humans; Immunosuppressive Agents; Ion Transport; Muscle, Smooth, Vascular; Receptors, Angiotensin; Up-Regulation

1999
Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2

    Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Diseases; Humans; Hypertension, Renal; Interleukin-6; Kidney; Male; Monocytes; Myocardium; Neutrophils; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Binding; Rats; Renin

2000
Involvement of calcineurin in angiotensin II-induced cardiomyocyte hypertrophy and cardiac fibroblast hyperplasia of rats.
    Heart and vessels, 1999, Volume: 14, Issue:6

    Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcineurin; Calcineurin Inhibitors; Calcium; Cardiomegaly; Cell Division; Cells, Cultured; Cyclosporine; DNA; Fibroblasts; Fura-2; Hyperplasia; Losartan; Myocardium; Protein Kinase C; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Signal Transduction

1999
Endothelin, angiotensin II and adenosine in acute cyclosporine A nephrotoxicity.
    Pediatric nephrology (Berlin, Germany), 2000, Volume: 14, Issue:10-11

    Topics: Acute Disease; Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclosporine; Endothelins; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Perindopril; Rabbits; Renal Circulation; Theophylline; Vascular Resistance; Water

2000
Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension.
    The Journal of biological chemistry, 2000, Dec-29, Volume: 275, Issue:52

    Topics: Angiotensin II; Animals; Calcineurin; Calcineurin Inhibitors; Cardiomegaly; Cyclosporine; Enzyme Activation; Hypertension, Renovascular; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardium; Protein Kinase C

2000
New approach in the therapy of chronic rejection? ACE- and AT1-blocker reduce the development of chronic rejection after cardiac transplantation in a rat model.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2000, Volume: 19, Issue:11

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Coronary Disease; Coronary Vessels; Cyclosporine; Enalapril; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Losartan; Male; Premedication; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Heterotopic

2000
Enalaprilat directly ameliorates in vitro cyclosporin nephrotoxicity in human tubulo-interstitial cells.
    Nephron, 2000, Volume: 86, Issue:4

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cell Division; Cell Survival; Cells, Cultured; Collagen; Culture Media, Conditioned; Cyclosporine; Cytokines; Enalaprilat; Fibroblasts; Humans; Immunosuppressive Agents; Kidney Cortex; Kidney Tubules, Proximal; Nephritis, Interstitial

2000
[Involvement of calcineurin-dependent signal pathway in the angiotensin II-induced cardiac myocyte hypertrophy].
    Sheng li xue bao : [Acta physiologica Sinica], 1999, Volume: 51, Issue:5

    Topics: Angiotensin II; Animals; Calcineurin; Cardiomegaly; Cells, Cultured; Cyclosporine; Myocardium; Rats; Signal Transduction

1999
Influence of the renin-angiotensin system on epidermal growth factor expression in normal and cyclosporine-treated rat kidney.
    Kidney international, 2001, Volume: 60, Issue:3

    Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Cyclosporine; Diet, Sodium-Restricted; Epidermal Growth Factor; Fibrosis; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Glomerulus; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System

2001
Angiotensin II induced cardiac hypertrophy in vivo is inhibited by cyclosporin A in adult rats.
    Molecular and cellular biochemistry, 2001, Volume: 226, Issue:1-2

    Topics: Angiotensin II; Animals; Blotting, Northern; Body Weight; Calcineurin; Calcium; Cardiomegaly; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hypertrophy; Myocardium; Organ Size; Rats; Rats, Wistar; RNA; Signal Transduction; Up-Regulation

2001
Angiotensin II inhibits human trophoblast invasion through AT1 receptor activation.
    The Journal of biological chemistry, 2002, Jul-05, Volume: 277, Issue:27

    Topics: Angiotensin II; Calcineurin; Cell Line; Cyclosporine; DNA-Binding Proteins; Embryo Implantation; Gene Expression Regulation; Humans; Losartan; NFATC Transcription Factors; Nuclear Proteins; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Trophoblasts

2002
Cyclosporin A inhibits angiotensin II-induced c-Jun NH(2)-terminal kinase activation but not protein synthesis in vascular smooth muscle cells.
    European journal of pharmacology, 2002, May-17, Volume: 443, Issue:1-3

    Topics: Angiotensin II; Animals; Anisomycin; Aorta, Thoracic; Cells, Cultured; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Leucine; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Tacrolimus

2002
Angiotensin II regulation of vascular endothelial growth factor and receptors Flt-1 and KDR/Flk-1 in cyclosporine nephrotoxicity.
    Kidney international, 2002, Volume: 62, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cyclosporine; Disease Models, Animal; Enalapril; Endothelial Growth Factors; Extracellular Matrix Proteins; Gene Expression; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Kidney Diseases; Losartan; Lymphokines; Male; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors

2002
Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.
    Transplantation, 2003, Feb-15, Volume: 75, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Body Weight; Chronic Disease; Cyclosporine; Drug Synergism; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney; Kidney Diseases; Losartan; Macrophages; Male; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
Effect of carvedilol alone or in the presence of cyclosporine on the migration of vascular smooth muscle cell of rat.
    Transplantation proceedings, 2003, Volume: 35, Issue:1

    Topics: Angiotensin II; Animals; Carbazoles; Carvedilol; Cells, Cultured; Chemotaxis; Cyclosporine; Immunosuppressive Agents; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Propanolamines; Rats; Rats, Sprague-Dawley

2003
Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
    The American journal of pathology, 2003, Volume: 163, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Calcineurin; Collagen Type I; Collagen Type III; Connective Tissue Growth Factor; Cyclosporine; Everolimus; Gene Expression Regulation; Heart; Humans; Immediate-Early Proteins; Immunosuppressive Agents; In Situ Hybridization; Intercellular Signaling Peptides and Proteins; Kidney; Male; Organisms, Genetically Modified; Rats; Rats, Sprague-Dawley; Renin; Sirolimus; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
Role of angiotensin II and reactive oxygen species in cyclosporine A-dependent hypertension.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Creatinine; Cyclic N-Oxides; Cyclosporine; Hypertension; Immunosuppressive Agents; Male; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan

2003
Cyclosporin increases the density of angiotensin II subtype 1 (AT1) receptors in mouse medullary thick ascending limb cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:8

    Topics: Angiotensin II; Animals; Calcium; Cell Survival; Cells, Cultured; Cyclosporine; Immunosuppressive Agents; Kidney Medulla; Male; Mice; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction

2003
Role of calcineurin in angiotensin II-induced cardiac myocyte hypertrophy of rats.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2001, Volume: 16, Issue:1

    Topics: Angiotensin II; Animals; Animals, Newborn; Atrial Natriuretic Factor; Calcineurin; Cardiomegaly; Cells, Cultured; Cyclosporine; Myocytes, Cardiac; Rats; Rats, Wistar; RNA, Messenger

2001
[Role of activation of renin angiotensin system in cyclosporine A nephropathy].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2003, Volume: 15, Issue:12

    Topics: Angiotensin II; Animals; Cyclosporine; Immunosuppressive Agents; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger

2003
Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation.
    Circulation research, 2004, Mar-19, Volume: 94, Issue:5

    Topics: Angiotensin II; Animals; Calcineurin; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomyopathy, Hypertrophic; Cells, Cultured; Chemokine CCL2; Cyclosporine; Femoral Artery; Gene Expression Regulation; Humans; Hyperplasia; Imidazoles; Macrophages; MAP Kinase Kinase 6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Pyridines; Rats; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Tetrazoles; Transcription, Genetic; Tunica Intima; Valine; Valsartan; Vasculitis

2004
Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:8

    Topics: Angiotensin II; Animals; Apoptosis; Cyclosporine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Islets of Langerhans; Kidney; Osteopontin; Pancreatic Diseases; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sialoglycoproteins; Thiazolidinediones; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Effect of FTY720 on chronic cyclosporine nephropathy in rats.
    Transplantation, 2005, Nov-15, Volume: 80, Issue:9

    Topics: Angiotensin II; Animals; Chronic Disease; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney; Kidney Diseases; Lymphocytes; Macrophages; Male; Osteopontin; Propylene Glycols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Pathways of glomerular toxicity of cyclosporine-A: an "in vitro" study.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:4

    Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin-1; Female; Kidney Glomerulus; Oligopeptides; Organ Culture Techniques; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors

2005
Effects of cyclosporine A on angiotensin II-induced cardiomyocyte hypertrophy in neonatal rats.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:5

    Topics: Angiotensin II; Animals; Animals, Newborn; Calcium; Cardiomegaly; Cells, Cultured; Cyclosporine; Myocytes, Cardiac; Proto-Oncogene Proteins c-fos; Rats

2005
The CARI guidelines. Prevention of progression of kidney disease.
    Nephrology (Carlton, Vic.), 2006, Volume: 11 Suppl 1

    Topics: Acidosis; Adult; Analgesics; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Child; Cyclosporine; Diabetic Nephropathies; Diet, Protein-Restricted; Exercise; Female; Fish Oils; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hyperuricemia; Kidney Diseases; Kidney Failure, Chronic; Phosphates; Pregnancy; Pregnancy Complications; Proteinuria; Renal Artery Obstruction; Smoking Cessation; Tonsillectomy

2006
Cardiomyoblast apoptosis induced by insulin-like growth factor (IGF)-I resistance is IGF-II dependent and synergistically enhanced by angiotensin II.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:7

    Topics: Angiotensin II; Animals; Antibodies; Apoptosis; bcl-Associated Death Protein; Calcineurin; Calcineurin Inhibitors; Caspase 3; Caspase 9; Caspases; Cell Line; Cyclosporine; Cytochromes c; DNA Fragmentation; Drug Synergism; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Models, Biological; Myoblasts, Cardiac; Oligonucleotides, Antisense; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptor, IGF Type 2; Signal Transduction; Tacrolimus; Transfection

2006
Cyclosporin A stimulates apical Na+/H+ exchange in LLC-PK1/PKE20 proximal tubular cells.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:7

    Topics: Angiotensin II; Animals; Blotting, Northern; Calcineurin Inhibitors; Calcium; Cyclosporine; Fluorescent Dyes; Fura-2; Hydrogen-Ion Concentration; Immunosuppressive Agents; LLC-PK1 Cells; Protein Kinase C; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Swine; Vasoconstrictor Agents

2006
Telmisartan attenuates chronic ciclosporin A nephrotoxicity in a pig model.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:2

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biopsy; Blood Flow Velocity; Blood Pressure; Cyclosporine; Disease Models, Animal; Female; Follow-Up Studies; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Failure, Chronic; Magnetic Resonance Imaging; Renal Circulation; Swine; Telmisartan; Treatment Outcome

2007
Prevention of interstitial fibrosis of renal allograft by angiotensin II blockade.
    Transplantation proceedings, 2006, Volume: 38, Issue:10

    Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cyclosporine; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Postoperative Complications

2006
Influence of angiotensin II on expression of toll-like receptor 2 and maturation of dendritic cells in chronic cyclosporine nephropathy.
    Transplantation, 2007, Apr-15, Volume: 83, Issue:7

    Topics: Angiotensin II; Animals; Cyclosporine; Dendritic Cells; Immunity, Innate; Kidney; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha

2007
Rac2 GTPase activation by angiotensin II is modulated by Ca2+/calcineurin and mitogen-activated protein kinases in human neutrophils.
    Journal of molecular endocrinology, 2007, Volume: 39, Issue:5

    Topics: Angiotensin II; Animals; Calcineurin; Calcium; Cell Membrane; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Humans; Mice; Mitogen-Activated Protein Kinases; Neutrophils; Phosphatidylinositol 3-Kinases; rac GTP-Binding Proteins; RAC2 GTP-Binding Protein; Reactive Oxygen Species; Signal Transduction

2007
In vitro effect of cyclosporine-A on angiotensins secretion by glomerular cells.
    Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:4

    Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Female; Immunosuppressive Agents; Kidney Glomerulus; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors; Tissue Culture Techniques; Up-Regulation

2008
Intrarenal activation of renin angiotensin system in the development of cyclosporine A induced chronic nephrotoxicity.
    Chinese medical journal, 2008, Jun-05, Volume: 121, Issue:11

    Topics: Adult; Aged; Angiotensin II; Cyclosporine; Endothelial Cells; Female; Humans; Immunosuppressive Agents; Kidney; Male; Middle Aged; Renin; Renin-Angiotensin System

2008
Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Angiotensin II; Animals; Blotting, Western; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Glucuronidase; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents

2011
HNF4alpha dysfunction as a molecular rational for cyclosporine induced hypertension.
    PloS one, 2011, Jan-27, Volume: 6, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Computational Biology; Consensus Sequence; Cyclosporine; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Hypertension; Immunosuppressive Agents; NFATC Transcription Factors; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Transcription, Genetic

2011
Epithelial phenotypic changes detect cyclosporine in vivo nephrotoxicity at a reversible stage.
    Transplantation, 2011, Nov-15, Volume: 92, Issue:9

    Topics: Acute Kidney Injury; Angiotensin II; Animals; beta Catenin; Biomarkers; Collagen Type III; Cyclosporine; Epithelial Cells; Epithelial-Mesenchymal Transition; HSP47 Heat-Shock Proteins; Immunosuppressive Agents; Kidney; Male; Models, Animal; Phenotype; Rats; Rats, Sprague-Dawley; Snail Family Transcription Factors; Transcription Factors; Up-Regulation; Vimentin

2011
Regulator of calcineurin 1 mediates pathological vascular wall remodeling.
    The Journal of experimental medicine, 2011, Sep-26, Volume: 208, Issue:10

    Topics: Aneurysm; Angiotensin II; Animals; Aorta; Calcineurin; Calcium-Binding Proteins; Cell Movement; Coronary Restenosis; Cyclosporine; Gene Expression Regulation; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Smooth, Vascular; NFATC Transcription Factors; Rats; Rats, Wistar; Signal Transduction

2011
Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A.
    Therapeutic advances in cardiovascular disease, 2012, Volume: 6, Issue:1

    Topics: Angiotensin II; Animals; Calcineurin; Cell Proliferation; Cyclosporine; Fibroblasts; Immunosuppressive Agents; Inflammation; Mitogen-Activated Protein Kinases; Myocardium; Phosphorylation; Rats; Rats, Inbred WKY; Signal Transduction; Tacrolimus

2012
Expression of angiotensin II and its receptors in cyclosporine-induced gingival overgrowth.
    Journal of periodontal research, 2013, Volume: 48, Issue:3

    Topics: Adult; Angiotensin II; Angiotensinogen; Case-Control Studies; Cells, Cultured; Chronic Periodontitis; Cyclosporine; Female; Fibroblasts; Gingival Overgrowth; Humans; Immunosuppressive Agents; Male; Middle Aged; Receptors, Angiotensin; Renin-Angiotensin System; Young Adult

2013
Cytosolic CARP promotes angiotensin II- or pressure overload-induced cardiomyocyte hypertrophy through calcineurin accumulation.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adenoviridae; Angiotensin II; Animals; Animals, Newborn; Aorta; Atrial Natriuretic Factor; Calcineurin; Calpain; Cardiomegaly; Constriction, Pathologic; Cyclosporine; Gene Expression Regulation; Genetic Vectors; Glycoproteins; Imidazoles; Mice; Muscle Proteins; Myocytes, Cardiac; Myosin Heavy Chains; Nuclear Proteins; Primary Cell Culture; Protein Transport; Rats; Repressor Proteins; RNA, Small Interfering; Signal Transduction; Tetrazoles

2014
An adenosine A1 agonist 2-chloro-N6 cyclopentyladenosine inhibits the angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin pathway.
    Cardiology, 2014, Volume: 129, Issue:3

    Topics: Adenosine A1 Receptor Agonists; Angiotensin II; Animals; Calcineurin; Cyclosporine; Enzyme Inhibitors; In Vitro Techniques; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Rats; RNA, Messenger; Signal Transduction

2014
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation

2016
Resveratrol ameliorates the cyclosporine-induced vascular and renal impairments: possible impact of the modulation of renin-angiotensin system.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:12

    Topics: Angiotensin II; Animals; Aorta; Cyclosporine; Cytoprotection; Dose-Response Relationship, Drug; Gene Expression Regulation; Kidney; Male; NADPH Oxidase 4; Rats; Rats, Wistar; Renin-Angiotensin System; Resveratrol; RNA, Messenger; Vasoconstriction; Vasodilation

2019
Angiotensin II receptor blockade alleviates calcineurin inhibitor nephrotoxicity by restoring cyclooxygenase 2 expression in kidney cortex.
    Acta physiologica (Oxford, England), 2021, Volume: 232, Issue:1

    Topics: Angiotensin II; Animals; Calcineurin Inhibitors; Cyclooxygenase 2; Cyclosporine; Kidney; Kidney Cortex; Rats; Receptors, Angiotensin

2021