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angiotensin ii and bosentan anhydrous

angiotensin ii has been researched along with bosentan anhydrous in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (41.30)18.2507
2000's24 (52.17)29.6817
2010's2 (4.35)24.3611
2020's1 (2.17)2.80

Authors

AuthorsStudies
Li, JS; Schiffrin, EL1
Lüscher, TF; Tschudi, MR1
Clozel, JP; Clozel, M; Gonzales, MF; Heudes, D; Karam, H; Löffler, BM1
Balakrishnan, SM; Gopalakrishnan, V; McNeill, JR; Wang, HD; Wilson, TW1
Ercan, ZS; Hodoglugil, U; Sipahi, E; Türker, RK1
Leskinen, H; Ruskoaho, H; Vuolteenaho, O1
Ardaillou, R; Chatziantoniou, C; Dussaule, JC; Essig, M; Vandermeersch, S1
Yamazaki, T; Yazaki, Y1
Heinemann, A; Holzer, P; Peskar, BA; Wachter, CH1
Bouriquet, N; Casellas, D; Herizi, A1
Herizi, A; Jover, B; Mimran, A1
Bouriquet, N; Herizi, A; Jover, B; Mimran, A1
Budde, M; Charlon, V; Krum, H; Lacourciere, Y; Viskoper, RJ1
Champion, HC; Estrada, LN; Estrada, LS; Filep, JG; Kadowitz, PJ1
Charlier, AA; Donckier, JE; Heyndrickx, GR; Hodeige, DG; Ketelslegers, JM; Massart, PE; Van Mechelen, H1
Endlich, K; Helwig, JJ; Muller, C1
Baylis, C; Qiu, C1
Borthayre, AB; Harrison, DG; Hink, U; Kurz, S; Münzel, T; Nickenig, G1
Bellissant, E; Durand-Castel, X; Goineau, S; Guillo, P; Pape, D1
Bertel, O; Clozel, M; Kiowski, W; Nicholls, MG; Rickenbacher, P; Sütsch, G; Yandle, TG1
Davis, G; Hammad, FT; Wheatley, AM1
Breu, V; Dechend, R; Ganten, D; Genersch, E; Haller, H; Löffler, BM; Luft, FC; Mervaala, EM; Muller, DN; Park, JK; Schmidt, F; Schneider, W1
Belabbas, H; Herizi, A; Jover, B; Mimran, A1
Clair, MJ; de Gasparo, M; Hendrick, JW; King, MK; Mandel, J; McElmurray, JH; Mukherjee, R; New, RB; Sampson, AC; Spinale, FG1
Juncos, LA; Manriquez, MC; Ortiz, MC; Romero, JC; Sanabria, E1
Baylis, C; Harvey, J; Riggleman, A1
Inagaki, K; Iwanaga, Y; Kataoka, K; Kihara, Y; Onozawa, Y; Sasayama, S; Yoneda, T1
Gopalakrishnan, V; McNeill, JR; Wilson, TW; Yu, M1
Hautala, N; Ruskoaho, H; Szokodi, I; Tenhunen, O1
Ficai, S; Herizi, A; Jover, B; Mimran, A1
Anderson, TJ; Badiwala, M; Dumont, AS; Fedak, PW; Ko, L; Lovren, F; Maitland, A; Rao, V; Triggle, CR; Verma, S1
Belloni, AS; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rossi, GP; Sartore, S1
Chen, J; Gu, Y; Lin, F; Lin, S; Ma, J; Yang, H; Zhu, W1
deChâtel, R; Ilves, M; Kinnunen, P; Piuhola, J; Ruskoaho, H; Szokodi, I; Vuolteenaho, O1
Belloni, AS; Kreutz, R; Nussdorfer, GG; Paul, M; Pessina, AC; Rossi, GP; Seccia, TM1
Evans, JJ; Lewis, LK; Nicholls, MG; Yandle, TG; Youssef, AH1
Cases, A; Gomez-Alamillo, C; Haas, JA; Juncos, LA; Romero, JC1
Inagaki, K; Iwanaga, Y; Izumi, T; Kihara, Y; Kita, T; Noma, A; Onozawa, Y; Sarai, N; Takenaka, H; Yoneda, T1
Capuano, V; Coulombe, A; Deroubaix, E; Ferron, L; Renaud, JF; Ruchon, Y1
Elena, JV; Grujić-Adanja, G; Jerkić, M; Jovović, D; López-Novoa, JM; Manero, MV; Marković-Lipkovski, J; Mihailović-Stanojević, N; Miloradović, Z; Nastić-Mirić, D; Prieto, MP; Rodríguez-Barbero, A; Vojvodić, SB1
Charles, CJ; Espiner, EA; Frampton, CM; Nicholls, MG; Rademaker, MT; Richards, AM1
Biswas, P; Centracchio, J; Dworkin, LD; Gong, R; Roy, A; Tolbert, E; Yango, A1
Matsumori, A1
Dhalla, NS; Rehsia, NS1
Courtman, DW; Rampersad, SN; Stewart, DJ; Suen, RS1
Akita, K; Isobe, S; Isoda, K; Iwakura, Y; Minamino, T; Niida, T; Ohtomo, F; Sano, M; Sato-Okabayashi, Y; Shimada, K1

Reviews

2 review(s) available for angiotensin ii and bosentan anhydrous

ArticleYear
[Cytokine antagonists and endothelin antagonists for therapy of heart failure].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2005, Feb-10, Volume: 94, Issue:2

    Topics: Angiotensin II; Animals; Antibodies, Monoclonal; Bosentan; Clinical Trials as Topic; Cytokines; Endothelins; Etanercept; Genetic Therapy; Heart Failure; Humans; Immunoglobulin G; Infliximab; Interleukin-10; Mast Cells; NF-kappa B; Proto-Oncogene Proteins c-kit; Pyridazines; Receptors, Tumor Necrosis Factor; Sulfonamides

2005
Potential of endothelin-1 and vasopressin antagonists for the treatment of congestive heart failure.
    Heart failure reviews, 2010, Volume: 15, Issue:1

    Topics: Angiotensin II; Animals; Antidiuretic Agents; Antihypertensive Agents; Benzazepines; Biomarkers; Bosentan; Catecholamines; Drug Therapy, Combination; Endothelin-1; Heart Failure; Humans; Peptides, Cyclic; Renin-Angiotensin System; Sulfonamides; Sympathetic Nervous System; Tolvaptan; Treatment Outcome; Vasopressins

2010

Trials

3 trial(s) available for angiotensin ii and bosentan anhydrous

ArticleYear
The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators.
    The New England journal of medicine, 1998, Mar-19, Volume: 338, Issue:12

    Topics: Adult; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Bosentan; Creatinine; Double-Blind Method; Endothelin Receptor Antagonists; Endothelin-1; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sulfonamides

1998
Regulation of aldosterone secretion in patients with chronic congestive heart failure by endothelins.
    The American journal of cardiology, 2000, Apr-15, Volume: 85, Issue:8

    Topics: Aldosterone; Angiotensin II; Antihypertensive Agents; Bosentan; Double-Blind Method; Endothelin Receptor Antagonists; Endothelins; Heart Failure; Humans; Middle Aged; Sulfonamides

2000
Combined inhibition of angiotensin II and endothelin suppresses the brain natriuretic peptide response to developing heart failure.
    Clinical science (London, England : 1979), 2004, Volume: 106, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bosentan; Cardiac Output; Cardiac Output, Low; Cardiac Pacing, Artificial; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Female; Infusions, Parenteral; Losartan; Natriuretic Peptide, Brain; Renin; Sheep; Sulfonamides

2004

Other Studies

41 other study(ies) available for angiotensin ii and bosentan anhydrous

ArticleYear
Effect of chronic treatment of adult spontaneously hypertensive rats with an endothelin receptor antagonist.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 25, Issue:4 Pt 1

    Topics: Administration, Oral; Angiotensin II; Animals; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Endothelin Receptor Antagonists; Endothelins; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides

1995
Characterization of contractile endothelin and angiotensin receptors in human resistance arteries: evidence for two endothelin and one angiotensin receptor.
    Biochemical and biophysical research communications, 1994, Oct-28, Volume: 204, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Azepines; Benzazepines; Bosentan; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indoles; Mammary Arteries; Muscle Contraction; Plasmids; Receptors, Angiotensin; Receptors, Endothelin; Sulfonamides; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Viper Venoms

1994
Respective role of humoral factors and blood pressure in aortic remodeling of DOCA hypertensive rats.
    American journal of hypertension, 1996, Volume: 9, Issue:10 Pt 1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Benzimidazoles; Blood Pressure; Bosentan; Calcium Channel Blockers; Desoxycorticosterone; Enalapril; Endothelin Receptor Antagonists; Endothelins; Hypertension, Renovascular; Male; Mibefradil; Rats; Rats, Wistar; Sulfonamides; Tetrahydronaphthalenes; Tunica Media

1996
Effect of an endothelin antagonist on hemodynamic responses to angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 28, Issue:5

    Topics: Angiotensin II; Animals; Bosentan; Endothelin-1; Hemodynamics; Male; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Sulfonamides

1996
Acute effect of endothelin-1 on lung oedema induced by alpha-naphthylthiourea (ANTU).
    Pharmacological research, 1996, Volume: 33, Issue:6

    Topics: Angiotensin II; Animals; Aspartic Acid Endopeptidases; Body Weight; Bosentan; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Male; Metalloendopeptidases; Organ Size; Pleural Effusion; Protease Inhibitors; Pulmonary Edema; Rats; Sulfonamides; Thiourea

1996
Combined inhibition of endothelin and angiotensin II receptors blocks volume load-induced cardiac hormone release.
    Circulation research, 1997, Volume: 80, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Function, Right; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Volume; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Hemodynamics; Hormones; Imidazoles; Losartan; Male; Myocardium; Natriuretic Peptide, Brain; Nerve Tissue Proteins; Peptides, Cyclic; Plasma Substitutes; Pressure; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles

1997
Modulation by angiotensin II of endothelial cell control of DNA synthesis in human mesangial cells.
    Nephron, 1997, Volume: 75, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Bosentan; Cell Division; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inhibitors; DNA; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Epoprostenol; Glomerular Mesangium; Humans; Indomethacin; Sulfonamides; Thymidine; Umbilical Veins

1997
Reversing congestive heart failure with endothelin receptor antagonists.
    Circulation, 1997, Apr-01, Volume: 95, Issue:7

    Topics: Aging; Angiotensin II; Animals; Bosentan; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Mice; Mice, Transgenic; Rabbits; Receptors, Endothelin; Sulfonamides

1997
Dilatation by angiotensin II of the rat femoral arterial bed in vivo via pressure/flow-induced release of nitric oxide and prostaglandins.
    British journal of pharmacology, 1997, Volume: 122, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Blood Pressure; Bosentan; Female; Femoral Artery; Hexamethonium; Indomethacin; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prazosin; Propranolol; Prostaglandins; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sulfonamides; Telmisartan; Vasodilation

1997
Bosentan prevents preglomerular alterations during angiotensin II hypertension.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:6

    Topics: Albuminuria; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Endothelin-1; Hypertension; Kidney Glomerulus; Male; Microscopy, Video; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides; Systole

1997
[Bosentan attenuates the hypertensive effect of angiotensin II in rats].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:8

    Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Drug Interactions; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Sulfonamides

1997
Prevention of the cardiovascular and renal effects of angiotensin II by endothelin blockade.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Endothelin Receptor Antagonists; Heart; Hemodynamics; Hypertension; Kidney; Male; Organ Size; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides

1998
Analysis of effects of bosentan (Ro 47-0203), a nonpeptide endothelin ETA/ETB receptor antagonist, in the hind-limb vascular bed of the cat.
    Canadian journal of physiology and pharmacology, 1998, Volume: 76, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Cats; Endothelin Receptor Antagonists; Endothelin-1; Hindlimb; Receptor, Endothelin B; Receptors, Endothelin; Sulfonamides; Vasoconstriction; Vasodilation; Vasopressins

1998
Angiotensin II and endothelin-1 receptor antagonists have cumulative hypotensive effects in canine Page hypertension.
    Journal of hypertension, 1998, Volume: 16, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bosentan; Disease Models, Animal; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Hypertension, Renovascular; Infusions, Intravenous; Losartan; Radioimmunoassay; Receptor, Endothelin A; Sulfonamides; Vascular Resistance

1998
AT2 antagonist-sensitive potentiation of angiotensin II-induced constriction by NO blockade and its dependence on endothelium and P450 eicosanoids in rat renal vasculature.
    British journal of pharmacology, 1998, Volume: 124, Issue:5

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Benzoflavones; Bosentan; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelin Receptor Antagonists; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Kidney; Male; Nitric Oxide; Norepinephrine; Perfusion; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Vascular Resistance; Vasoconstriction

1998
Endothelin and angiotensin mediate most glomerular responses to nitric oxide inhibition.
    Kidney international, 1999, Volume: 55, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Kidney Glomerulus; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Renal Circulation; Sulfonamides

1999
Evidence for a causal role of the renin-angiotensin system in nitrate tolerance.
    Circulation, 1999, Jun-22, Volume: 99, Issue:24

    Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Female; Gene Expression; Losartan; Luminescent Measurements; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide; Nitroglycerin; Peptidyl-Dipeptidase A; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sulfonamides; Superoxides; Vasoconstriction; Vasodilation; Vasodilator Agents

1999
Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Bosentan; Calcium; Calcium Channel Blockers; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Space; Glycopeptides; Hypoxia; In Vitro Techniques; Indoles; Lisinopril; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Pulmonary Artery; Rats; Rats, Wistar; Sulfonamides

1999
Long-term renal effects of unilateral ureteral obstruction and the role of endothelin.
    Kidney international, 2000, Volume: 58, Issue:1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Captopril; Endothelins; Hypertension, Renal; Male; Rats; Rats, Wistar; Sulfonamides; Ureteral Obstruction; Urodynamics; Vasoconstrictor Agents

2000
Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:2

    Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Bosentan; Cardiomegaly; Fibronectins; Heart; Humans; Hydralazine; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides; Thromboplastin; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1

2000
[Cardiac and vascular hypertrophy in hypertension due to angiotensin II. Effect of losartan and bosentan].
    Archives des maladies du coeur et des vaisseaux, 2000, Volume: 93, Issue:8

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Cardiomegaly; Carotid Arteries; Endothelin Receptor Antagonists; Endothelins; Follow-Up Studies; Hypertension; Hypertrophy; Losartan; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sulfonamides

2000
Effects of combined angiotensin II and endothelin receptor blockade with developing heart failure: effects on left ventricular performance.
    Circulation, 2000, Sep-19, Volume: 102, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bosentan; Cardiac Pacing, Artificial; Combined Modality Therapy; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Myocardial Contraction; Norepinephrine; Receptor, Endothelin A; Renin; Sulfonamides; Swine; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left

2000
Role of endothelin and isoprostanes in slow pressor responses to angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bosentan; Endothelins; Glomerular Filtration Rate; Infusions, Intravenous; Losartan; Nitrites; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sulfonamides

2001
Endothelin mediates some of the renal actions of acutely administered angiotensin II.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Bosentan; Endothelin Receptor Antagonists; Endothelins; Kidney; Kidney Function Tests; Male; Peptides, Cyclic; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sulfonamides

2001
Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure.
    Circulation, 2001, Jul-31, Volume: 104, Issue:5

    Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Disease Progression; Endothelin-1; Endothelins; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Male; Organ Size; Peptidyl-Dipeptidase A; Protein Precursors; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Survival Analysis; Thiazepines; Time Factors

2001
Endothelin antagonist reduces hemodynamic responses to vasopressin in DOCA-salt hypertension.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Blood Pressure; Bosentan; Cardiac Output; Desoxycorticosterone; Endothelin-1; Hemodynamics; Hypertension; Male; Rats; Rats, Sprague-Dawley; Sodium Chloride; Sulfonamides; Vascular Resistance; Vasoconstrictor Agents

2001
Direct left ventricular wall stretch activates GATA4 binding in perfused rat heart: involvement of autocrine/paracrine pathways.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autocrine Communication; Benzimidazoles; Biphenyl Compounds; Bosentan; Catheterization; DNA-Binding Proteins; Endothelin Receptor Antagonists; Endothelin-1; GATA4 Transcription Factor; In Vitro Techniques; Male; Myocardium; Paracrine Communication; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Sulfonamides; Tetrazoles; Transcription Factor AP-1; Transcription Factors; Ventricular Function

2002
Endothelin blockade in angiotensin II hypertension: prevention and treatment studies in the rat.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:12

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bosentan; Carotid Arteries; Endothelin Receptor Antagonists; Hypertension; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Sulfonamides

2001
Endothelin blockade potentiates endothelial protective effects of ACE inhibitors in saphenous veins.
    The Annals of thoracic surgery, 2002, Volume: 73, Issue:4

    Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bosentan; Coronary Artery Bypass; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Humans; In Vitro Techniques; Middle Aged; Nitroprusside; Peptides, Cyclic; Saphenous Vein; Sulfonamides; Vasoconstriction; Vasodilation; Vasodilator Agents

2002
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
    Cardiovascular research, 2002, Volume: 55, Issue:1

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles

2002
Endothelin receptor antagonist combined with a calcium channel blocker attenuates renal injury in spontaneous hypertensive rats with diabetes.
    Chinese medical journal, 2002, Volume: 115, Issue:7

    Topics: Amlodipine; Angiotensin II; Animals; Bosentan; Calcium Channel Blockers; Collagen Type IV; Diabetic Nephropathies; Drug Therapy, Combination; Endothelin Receptor Antagonists; Hypertension; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sulfonamides; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles

2003
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
    Journal of the American College of Cardiology, 2003, Feb-19, Volume: 41, Issue:4

    Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents

2003
Endothelin-1 directly modulates its own secretion: studies utilising the cell immunoblot technique.
    Regulatory peptides, 2003, May-15, Volume: 113, Issue:1-3

    Topics: Angiotensin II; Bosentan; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Humans; Immunoblotting; Oligopeptides; Piperidines; Sulfonamides

2003
Interactions between vasoconstrictors and vasodilators in regulating hemodynamics of distinct vascular beds.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 42, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bosentan; Cyclooxygenase Inhibitors; Dogs; Endothelin Receptor Antagonists; Enzyme Inhibitors; Female; Hemodynamics; Iliac Artery; Kidney; Lung; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Receptor, Angiotensin, Type 1; Regional Blood Flow; Sodium; Sulfonamides; Vasoconstriction; Vasodilation

2003
Reinduction of T-type calcium channels by endothelin-1 in failing hearts in vivo and in adult rat ventricular myocytes in vitro.
    Circulation, 2003, Nov-18, Volume: 108, Issue:20

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Calcium Channels, T-Type; Cells, Cultured; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Heart Ventricles; Male; Myocytes, Cardiac; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sulfonamides

2003
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
    Circulation research, 2003, Dec-12, Volume: 93, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; Calcium Channels, T-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Constriction, Pathologic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Gene Expression; Losartan; Male; Membrane Potentials; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nickel; Nitriles; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Sulfonamides

2003
Relative roles of endothelin-1 and angiotensin II in experimental post-ischaemic acute renal failure.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Infusions, Intravenous; Kidney; Losartan; Male; Models, Animal; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides

2004
Hepatocyte growth factor induces an endothelin-mediated decline in glomerular filtration rate.
    American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bosentan; Cattle; Cells, Cultured; Drug Administration Schedule; Endothelin-1; Glomerular Filtration Rate; Hepatocyte Growth Factor; Kidney; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles

2005
Differential roles of endothelin-1 in angiotensin II-induced atherosclerosis and aortic aneurysms in apolipoprotein E-null mice.
    The American journal of pathology, 2011, Volume: 179, Issue:3

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm; Apolipoproteins E; Atherosclerosis; Biomechanical Phenomena; Bosentan; Cardiovascular Agents; Cell Adhesion; Collagen; Down-Regulation; Endothelin-1; Integrin beta1; Interferon-gamma; Mice; Mice, Knockout; Stress, Physiological; Sulfonamides; Vasoconstrictor Agents

2011
Blocking of interleukin-1 suppresses angiotensin II-induced renal injury.
    Clinical science (London, England : 1979), 2021, 09-17, Volume: 135, Issue:17

    Topics: Angiotensin II; Animals; Antibodies; Blood Pressure; Bosentan; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypertension; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction

2021