angiotensin ii has been researched along with avapro in 217 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 44 (20.28) | 18.2507 |
| 2000's | 127 (58.53) | 29.6817 |
| 2010's | 40 (18.43) | 24.3611 |
| 2020's | 6 (2.76) | 2.80 |
| Authors | Studies |
|---|---|
| De Backer, JP; Fierens, FL; Fraeyman, N; Vanderheyden, PM; Vauquelin, G | 1 |
| Cazaubon, C; Chatelain, P; Christophe, B; Libon, R; Manning, A; Nisato, D | 1 |
| Brunner, HR; Burnier, M; Nussberger, J; Pechère-Bertschi, A; Waeber, B | 1 |
| Briand, R; Martineau, D; Yamaguchi, N | 1 |
| Admiraal, PJ; Blankestijn, PJ; Boomsma, F; de Ronde, WA; Janssen, JA; Kroodsma, JM; Man In 't Veld, AJ; Mulder, PG; Sissmann, J; van den Meiracker, AH | 1 |
| Fox, M; Panchal, BC; Trippodo, NC | 1 |
| Berger, Y; Bourrié, M; Fabre, G; Magdalou, J; Marti, E; Massé, D; Perrier, L; Tronquet, C | 1 |
| Cazaubon, C; Donat, F; Marchionni, D; Nisato, D; Roccon, A; Segondy, D | 1 |
| Giudicelli, JF; Moreau, N; Richer, C; Vincent, MP | 1 |
| Cazaubon, C; Chatelain, P; Delisée, C; Dol, F; Herbert, JM; Nisato, D; Schaeffer, P | 1 |
| Assens, JL; Bernhart, CA; Clément, J; Ferrari, BP; Haudricourt, F; Muneaux, CF; Muneaux, YA; Perreaut, PM; Taillades, JE; Vignal, MA | 1 |
| Cazaubon, C; Lacour, C; Nisato, D; Roccon, A; Segondy, D | 1 |
| Velasquez, MT | 1 |
| Benigni, A; Lapinski, R; Perico, N; Remuzzi, A; Remuzzi, G; Sangalli, F | 1 |
| Biollaz, J; Brunner, HR; Buclin, T; Burnier, M; Nussberger, J; Waeber, B | 1 |
| Brouard, R; MacFadyen, RJ; McIntyre, M; Meredith, PA; Reid, JL | 1 |
| Blumenfeld, J; Bragat, AC; Sealey, JE | 1 |
| García-Sáinz, JA; González-Espinosa, C; Martínez-Alfaro, M; Romero-Avila, MT | 1 |
| Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR | 1 |
| Flack, JM; Krieger, EM; Larochelle, P; Marbury, TC; Reeves, RA; Sareli, P | 1 |
| Gillis, JC; Markham, A | 1 |
| Brillet, G; Brouard, R; Grunfeld, JP; Lacour, B; Martinez, F; Nguyen-Khoa, T; Schmitt, F; Sissmann, J | 1 |
| Ford, NF; Langenbacher, KM; Lasseter, KC; Marino, MR; Raymond, RH | 1 |
| Cazaubon, C; Ciccocioppo, R; Massi, M; Nisato, D; Polidori, C | 1 |
| Barbhaiya, RH; Chando, TJ; Everett, DW; Greene, DS; Shyu, WC; Vachharajani, NN | 1 |
| Henrion, D; Luvarà, G; Mandet, C; Michel, JB; Philippe, M; Pueyo, ME; Savoie, F | 1 |
| Carraway, JW; Holycross, BJ; McCune, SA; Park, S; Radin, MJ | 1 |
| Chung, O; Csikós, T; Unger, T | 1 |
| Culman, J; Piepenburg, B; Rascher, W; Unger, T; von Heyer, C | 1 |
| Brunner, HR; Burnier, M; Maillard, M; Mazzolai, L; Nussberger, J; Rossat, J | 1 |
| Kulbertus, H | 1 |
| Baan, J | 1 |
| Cazaubon, C; Domergue, V; Fornes, P; Giudicelli, JF; Nisato, D; Richer, C | 1 |
| Abrahamsson, T; Adler, G; Brandt-Eliasson, U; Karp, L; Morsing, P; Ohlson, K; Renberg, L; Sjöquist, PO | 1 |
| Kirk, JK | 1 |
| De Backer, JP; Fierens, FL; Vanderheyden, PM; Vauquelin, G | 1 |
| Díez, J; Fortuño, A; Fortuño, MA; Muñiz, P; Ravassa, S; Rodriguez, JA; Zalba, G | 1 |
| Kaplan, NM | 1 |
| Willenheimer, R | 1 |
| Belz, GG; Butzer, R; Kober, S; Mang, C; Mutschler, E | 1 |
| Berger, Y; Caix, J; Davi, H; DuPont, P; Miscoria, G; Perrier, L; Simiand, J; Tronquet, C | 1 |
| Fluharty, SJ; Hines, J; Sakai, RR | 1 |
| Coca, A; Giner, V | 1 |
| Brunner, HR; Burnier, M; Centeno, C; Daven, V; Maillard, MP; Mazzolai, L; Nussberger, J | 1 |
| Doerr, G; Fleck, E; Graf, K; Kappert, K; Schmidt, G; Wollert-Wulf, B | 1 |
| Cody, RJ; Goetze, S; Graf, K; Hsueh, WA; Kawano, H; Kawano, Y; Law, RE; Schnee, J | 1 |
| Danser, AH; de Vries, R; MaassenVanDenBrink, A; Saxena, PR; Schalekamp, MA | 1 |
| Bonarjee, VV; Dickstein, K | 1 |
| Benedict, C; Bunt, AM; Conlin, PR; Ribeiro, AB; Saito, I; Spence, JD; Williams, B | 1 |
| Casado, S; Farré, J; Gómez, J; Jiménez, A; López-Blaya, A; López-Farré, A; Montón, M; Núñez, A; Sánchez de Miguel, L; Zalba, LR | 1 |
| Jarvis, B; Markham, A; Spencer, CM | 1 |
| DelGrande, D; Shetty, SS | 1 |
| Goossens, JF; Hénichart, JP; Houssin, R; Le Bourdonnec, B; Meulon, E; Yous, S | 1 |
| Howes, L; Wong, W | 1 |
| Bianchetti, MG; Teuffel, O; von Vigier, RO; Zberg, PM | 1 |
| Demukaj, S; Dikow, R; Fliser, D; Ritz, E | 1 |
| Fierens, FL; Vanderheyden, PM; Vauquelin, G | 1 |
| Badguet, JP; Mallion, JM | 1 |
| Barthel, H; Gonzàlez, M; Obal, D; Preckel, B; Schlack, W; Thämer, V | 1 |
| Ahlbory, K; Bäumer, AT; Böhm, M; Grohé, C; Nickenig, G; Rösen, R; Strehlow, K; van Eickels , M; Wassmann, S | 1 |
| Burnier, M | 1 |
| De Backer, JP; Fierens, FL; Morsing, P; Vanderheyden, PM; Vauquelin, G | 1 |
| Baican, M; Coltau, M; Domuta, G; Gilau, L; Hecht, A; Pasca, R; Puscas, I | 1 |
| El Mabrouk, M; He, G; Schiffrin, EL; Touyz, RM | 1 |
| Leenen, FH; Yuan, B | 1 |
| Campbell, DJ; Dodic, M; Peers, A; Wintour, EM | 1 |
| Vidt, DG | 1 |
| Mercure, C; Reudelhuber, TL; Touyz, RM | 1 |
| Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA | 2 |
| Armagnac, C; Mimran, A; Picard, A; Ribstein, J; Sissmann, J | 1 |
| Ramahi, TM | 1 |
| Angelini, A; Battista Ambrosio, G; Dalla Libera, L; Ravara, B; Rossini, K; Sandri, M; Thiene, G; Vescovo, G | 1 |
| Holycross, BJ; McCune, SA; Radin, MJ; Sharkey, LC | 1 |
| Allen, TJ; Bonnet, F; Cao, Z; Cooper, ME; Davis, B | 1 |
| Díez, J; Fortuño, A; Fortuño, MA; Muñiz, P; Zalba, G | 1 |
| Giatas, N; Golic Grdadolnik, S; Iliodromitis, EK; Keivish, T; Kremastinos, DT; Matsoukas, J; Mavromoustakos, T; Mutule, I; Polevaya, L; Roumelioti, P; Vlahakos, DV; Zoumboulakis, P | 1 |
| Balt, JC; Mathy, MJ; Nap, A; Pfaffendorf, M; van Zwieten, PA | 2 |
| Fierens, F; Vanderheyden, P; Vauquelin, G; Verheijen, I | 1 |
| Li, Q; Pfaffendorf, M; van Zwieten, PA | 1 |
| Elghozi, JL; Fassot, C; Lambert, E; Lambert, G | 1 |
| Goldenberg, I; Grossman, E; Jacobson, KA; Shainberg, A; Shneyvays, V | 1 |
| Connell, JM; Hillier, C; McDonald, JE; McMurray, JJ; Padmanabhan, N; Petrie, MC | 1 |
| Andersen, S; Arner, P; Brøchner-Mortensen, J; Gomis, R; Lehnert, H; Parving, HH | 1 |
| Atkins, RC; Cooper, ME; Gilbert, RE; Jerums, G | 1 |
| Basdew, M; Danser, AH; de Vries, R; Saxena, PR; Schoemaker, RG; Schuijt, MP; van Veghel, R | 1 |
| Beevers, DG; Lip, GY | 1 |
| Danser, AH; de Vries, R; Saxena, PR; Schalekamp, MA; Schuijt, MP | 1 |
| Bonnet, F; Cao, Z; Cox, A | 1 |
| Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; Jardine, E; Lygate, CA | 1 |
| Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Nussberger, J; Würzner, G | 1 |
| Arner, P | 1 |
| Belz, GG; Butzer, R; Kober, S; Mutschler, E | 1 |
| Mathy, MJ; Pfaffendorf, M; Streefkerk, JO; van Zwieten, PA | 1 |
| Engeli, S; Gorzelniak, K; Janke, J; Luft, FC; Sharma, AM | 1 |
| Belloni, AS; Cavallin, M; Mazzocchi, G; Nussdorfer, GG; Pessina, AC; Rossi, GP; Sartore, S | 1 |
| Berdyshev, AH; Bukhanevich, OM; Hula, NM; Kosiakova, HV; Kotsiuruba, AV; Mishchenko, LA; Radchenko, VV; Svishchenko, IeP | 1 |
| Brunner, HR; Burnier, M; Centeno, C; Maillard, MP; Perregaux, C; Stangier, J; Wienen, W | 1 |
| Balt, JC; Nap, A; Pfaffendorf, M; Van Zwieten, PA | 1 |
| Bottari, S; De Backer, JP; Vanderheyden, PM; Vauquelin, G; Verheijen, I | 1 |
| Cauvin, C; Durant, F; Goossens, JF; Hénichart, JP; Houssin, R; Le Bourdonnec, B; Meulon, E; Yous, S | 1 |
| Bernadet-Monrozies, P; Durand, D; Kamar, N; Rostaing, L | 1 |
| Alvarez, A; Fernández-Calotti, P; Gamberale, R; Geffner, JR; Giordano, M; Nahmod, KA; Nahmod, V; Raiden, S; Salamone, G; Vermeulen, ME | 1 |
| Dikow, R; Eberhard, R | 1 |
| Belloni, AS; Kreutz, R; Nussdorfer, GG; Paul, M; Pessina, AC; Rossi, GP; Seccia, TM | 1 |
| Atkins, RC; Bucala, R; Cao, Z; Cooper, ME; Metz, CN; Nikolic-Paterson, DJ; Rice, EK; Tesch, GH | 1 |
| Hollenberg, NK; Price, DA | 1 |
| Berl, T; Drury, PL; Esmatjes, E; Goldhaber, SZ; Hricik, D; Hunsicker, LG; Lewis, EJ; Lewis, JB; Locatelli, F; Parikh, CR; Pfeffer, MA; Porush, JG; Raz, I; Rouleau, JL; Vanhille, P; Wiegmann, TB; Wolfe, BM | 1 |
| Schieffer, B; Schmidt, B | 1 |
| Balt, JC; Nap, A; Pfaffendorf, M; Zwieten, PA | 1 |
| Bessard, G; Caron, F; Cracowski, JL; Hakim, A; Hoffmann, P; Sessa, C; Stanke-Labesque, F | 1 |
| Mohanram, A; Toto, RD | 1 |
| Gironacci, M; Höcht, C; Opezzo, JA; Peña, C; Taira, CA | 1 |
| Leunissen, JD; Londoño, C; Ramakers, C; Schoenmakers, M; van Opstal, JM; Vos, MA | 1 |
| de Jong-van den Berg, LT; de Zeeuw, D; Kruidhof, H; Postma, MJ | 1 |
| Bianchetti, MG; Edefonti, A; Fossali, E; Gartenmann, AC; Schmidtko, J; Simonetti, GD; von Vigier, RO | 1 |
| Dominiak, P; Häuser, W | 1 |
| Andersen, S; Bröchner-Mortensen, J; Parving, HH | 1 |
| Höcht, C; Opezzo, JA; Taira, CA | 1 |
| Cao, B; Feng, QH; Li, S; Li, XZ | 1 |
| Ruilope, LM; Segura, J | 1 |
| Bei, R; Bucci, M; Cipollone, F; Cuccurullo, C; Cuccurullo, F; de Cesare, D; De Luca, M; Fazia, M; Iezzi, A; Mezzetti, A; Muraro, R; Pini, B; Spigonardo, F; Ucchino, S; Zucchelli, M | 1 |
| Croom, KF; Curran, MP; Goa, KL; Perry, CM | 1 |
| Chen, Q; Liu, BC; Luo, DD; Ma, KL; Ruan, XZ; Sun, J | 1 |
| Batenburg, WW; Bernasconi, CC; Danser, AH; Garrelds, IM; Juillerat-Jeanneret, L; Saxena, PR; van Kats, JP | 1 |
| Chen, SL; Wang, JM; Zhu, ZS | 1 |
| Daigle, C; Dao, HH; Girardot, D; Martens, FM; Moreau, P; Touyz, RM | 1 |
| Golledge, J; Karan, M; Lam, A; Mangan, S; McCann, M | 1 |
| Ahn, JY; Ahn, TH; Chung, WJ; Han, SH; Jin, DK; Kang, WC; Kim, HS; Koh, KK; Park, GS; Shin, EK | 1 |
| Berni, A; Calvo, N; Cigarrán, S; Coronel, F; Herrero, JA | 1 |
| Cachofeiro, V; Cediel, E; de Las Heras, N; Lahera, V; Sanz-Rosa, D; Velasco, O | 1 |
| Baska, RA; Beyer, SM; Carlson, KE; Dickinson, KE; Ewing, WR; Fadnis, L; Gu, Z; Humphreys, WG; Kowala, MC; Lan, SJ; Macor, JE; Monshizadegan, H; Murugesan, N; Tellew, JE; Valentine, MT; Yang, Y; Zahler, R | 1 |
| Ferrannini, E; Santini, E; Solini, A | 1 |
| Isreb, MA; Leehey, DJ; Marcic, S; Singh, AK; Singh, R | 1 |
| Blanchet, M; Curnier, D; De Champlain, J; Ducharme, A; Lamoureux, MC; Racine, N; Sheppard, R; Sirois, P; Tardif, JC; White, M | 1 |
| Aurell, M; Herlitz, H; Palmgren, E; Widgren, B | 1 |
| Clasen, R; Clemenz, M; Foryst-Ludwig, A; Kintscher, U; Krikov, M; Schupp, M; Sprang, C; Thöne-Reineke, C; Unger, T | 1 |
| Golledge, J; Karan, M; Ketheesan, N; McCann, M; Moran, CS; Norman, P | 1 |
| Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K | 1 |
| Guan, XD; Wu, YF; Zhao, W | 1 |
| Boasquevisque, EM; de Lourdes Rodrigues, M; Francischetti, EA; Genelhu, V; Ismerim, VL; Matos, JP | 1 |
| Feng, YQ; Nie, J; Wei, F; Zhang, M; Zhang, YF | 1 |
| Diehl, CJ; Henriksen, EJ; Kim, JS; Saengsirisuwan, V; Sloniger, JA | 1 |
| Chen, L; Huang, HQ; Liu, BC; Liu, DG; Liu, H; Ma, KL; Sun, J; Zhang, XL | 1 |
| Allard, SE; Browne, DL; Cummings, MH; Meeking, DR; Munday, JL; Shaw, KM | 1 |
| Cipollone, F; Fazia, ML; Mezzetti, A | 1 |
| Boix, E; Moreno, O; Picó, A; Zapater, P | 1 |
| Athanasiadis, GI; Kollmar, A; Ollert, M; Pfab, F; Ring, J | 1 |
| Gavras, H; Ribeiro, AB | 1 |
| Batenburg, WW; Danser, AH; Dekkers, DH; Garrelds, IM; Jorde, U; Kellett, E; Lamers, JM; Milligan, G; van Esch, JH; van Kats, JP; Walther, T | 1 |
| Boomsma, F; de Beer, VJ; Duncker, DJ; Haitsma, DB; Lamers, JM; Merkus, D; Sorop, O; Verdouw, PD | 1 |
| Argentino, DP; Dominici, FP; Muñoz, MC; Toblli, JE; Turyn, D | 1 |
| Gordillo-Moscoso, A; Padilla, E; Redondo, S; Ruiz, E; Tejerina, T | 1 |
| Backx, PH; Butany, J; Chappell, M; Kassiri, Z; Khokha, R; Oudit, GY; Patel, MP; Penninger, JM; Scholey, JW; Tsushima, RG | 1 |
| Balfagón, G; Gordillo-Moscoso, A; Padilla, E; Redondo, S; Ruiz, E; Salaices, M; Tejerina, T | 1 |
| Jones, MR; Laragh, JH; Sealey, JE | 1 |
| Bhaumik, A; Franklin, SS; Lapuerta, P; Neutel, JM; Ptaszynska, A | 1 |
| Cao, G; Mastai, R; Mella, J; Muñoz, MC; Pereyra, L; Toblli, JE | 1 |
| Boomsma, F; de Beer, VJ; Dekkers, DH; Duncker, DJ; Lamers, JM; Merkus, D; Pijnappels, DA; Sorop, O | 1 |
| Gómez, O; Molina-Holgado, E; Uceda, ER; Vera, ME; Vieitez, P | 1 |
| Hay, M; Johnson, AK; Xue, B; Zhao, Y | 1 |
| Li, XP; Liu, QM; Shen, XQ; Zhang, M; Zhao, SP; Zhou, SH | 1 |
| Jing, L; Kou, JJ; Li, S; Li, WM; Song, J; Zhou, LJ | 1 |
| Fortin, C; Lacasse, Y; Lacourciere, Y; Maltais, F; Marquis, K; Poirier, P | 1 |
| Preobrazhenksiĭ, DV | 1 |
| Alfarano, C; Cerbai, E; Failli, P; Franchi-Micheli, S; Mannucci, E; Mugelli, A; Raimondi, L | 1 |
| Basu, R; Guo, D; Kassiri, Z; Liu, PP; Oudit, GY; Penninger, JM; Scholey, JW; Wang, X; Zhong, J | 1 |
| Ferrario, CM; Habibi, J; Hayden, MR; Johnson, MS; Nistala, R; Rehmer, N; Schneider, RI; Sowers, JR; Tilmon, R; Whaley-Connell, A | 1 |
| Savvatis, K; Schultheiss, HP; Tschöpe, C; Westermann, D | 1 |
| Danser, AH; Moltzer, E; van Esch, JH; van Veghel, R; Verkuil, AV | 1 |
| Hu, D; Li, Y; Liu, N; Ren, L; Sheng, Z; Tang, R | 1 |
| Bramlage, P; Schindler, C | 1 |
| Kumagai, K | 1 |
| Fox, DA; Kashihara, N; Morita, Y; Sakuta, T; Satoh, M | 1 |
| de Beer, VJ; de Graaff, HJ; Duncker, DJ; Hoekstra, M; Merkus, D | 1 |
| Arsenault, J; Cabana, J; Escher, E; Guillemette, G; Lanthier, L; Lavigne, P; Leduc, R; Lehoux, J | 1 |
| Danser, AH; Deinum, J; Geurts, AC; Groothuis, JT; Hopman, MT; Rongen, GA; Smits, P; Thijssen, DH | 1 |
| Dai, H; Li, Q; Liu, B; Lv, L; Ma, K; Tang, R; Zheng, M | 1 |
| Cherney, DZ; Lai, V; Miller, JA; Reich, HN; Scholey, JW | 1 |
| Maeda, S; Matsui, T; Nishino, Y; Takeuchi, M; Yamagishi, S | 1 |
| Barden, A; Beilin, LJ; Croft, KD; Puddey, IB; Tsai, IJ | 1 |
| Medvedev, IN; Simonenko, VB; Tolmachev, VV | 1 |
| Burger, D; Carter, A; He, Y; Montezano, AC; Nishigaki, N; Touyz, RM | 1 |
| Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Toyama, K; Yamamoto, E; Yasuda, O | 1 |
| Cheng, YX; Lai, WY; Li, N; Li, X; Meng, Y; Niu, Y; Shen, B | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nako, H; Ogawa, H; Toyama, K; Yamamoto, E; Yasuda, O | 1 |
| Anand, IS; Carson, PE; Komajda, M; Kuskowski, M; Massie, BM; McKelvie, RS; McMurray, JJ; Rector, TS; Zile, MR | 1 |
| Du, N; Feng, J; Hu, LJ; Ren, H; Sun, HB; Sun, X; Yang, YP; Zhao, Y | 1 |
| Chen, C; Chen, Q; Li, ZG; Liang, Z | 1 |
| Aderkast, C; Bukowska, A; Busch, M; Chilukoti, RK; Felix, SB; Goette, A; Homuth, G; Lendeckel, U; Mostertz, J; Völker, U; Wolke, C | 1 |
| Clancy, P; Golledge, J; Koblar, SA; Seto, SW | 1 |
| Erfinanda, L; Gembardt, F; Kaestle, SM; Klein, N; Kuebler, WM; Lei, X; Mertens, M; Nickles, H; Supé, S; Szaszi, K; Walther, T; Wang, L; Yin, J | 1 |
| Bigagli, E; Lodovici, M; Manni, ME; Musilli, C; Raimondi, L; Zazzeri, M | 1 |
| Gao, PJ; Jin, HY; Lu, L; Oudit, GY; Penninger, JM; Shang, QH; Song, B; Xu, YL; Zhang, ZZ; Zhong, JC; Zhou, T; Zhu, DL | 1 |
| Inoue, T; Ishii, N; Miyazaki, T; Nishiyama, A; Ohno, Y; Suzuki, H; Takenaka, T | 1 |
| Chen, Q; Huang, D; Huang, S; Lei, W; Pang, L | 1 |
| Özcan, EE; Özel, E; Öztürk, A; Senaslan, Ö; Uyar, S | 1 |
| Bai, F; Li, XL; Lin, X; Ma, RX; Song, RX; Yu, J | 1 |
| Heller, JP; Leung, J; Martin, KR; Tassoni, A; White, AJ | 1 |
| Fukai, T; Itoh, S; Matsuda, S; Matsuzaki, M; Murata, T; Umemoto, S; Yoshimura, K | 1 |
| Fukai, T; Itoh, S; Matsuda, S; Matsuzaki, M; Murata, T; Nakashima, T; Umemoto, S; Yoshimura, K | 1 |
| Azegami, T; Hayashi, K; Itoh, H; Nakamura, M; Oguchi, H; Sakamaki, Y; Sasamura, H; Tokuyama, H; Wakino, S | 1 |
| Anand, IS; Carson, PE; Kao, DP; Komajda, M; Lewsey, JD; Lindenfeld, J; Massie, BM; McKelvie, RS; McMurray, JJ; Zile, MR | 1 |
| Abdulla, MH; Abdullah, NA; Afzal, S; Akhtar, S; Hashmi, F; Johns, EJ; Sattar, MA | 1 |
| Al-Jarallah, A; Babiker, F; Joseph, S | 1 |
| Gong, WQ; Huang, WC; Liang, Y; Liu, B; Yang, CM; Ye, XL; Zheng, YT | 1 |
| Lei, H; Li, J; Li, L; Liu, H; Yi, J | 1 |
| Dong, Y; George, V; Ghosh, S; Hanevold, CD; Harshfield, GA; Jasti, A; Pollock, D; Pollock, J; Treiber, FA | 1 |
| Ao, X; Kwadwo Nuro-Gyina, P; Li, X; Lu, Y; Meng, T; Peng, L; Tang, R; Wang, W; Xiao, C; Zhong, Y; Zhou, Q | 1 |
| Dai, F; Guan, H; Liang, X; Qi, Y; Sun, J; Yao, W | 1 |
| Chen, JW; Dai, B; Han, MX; Wang, ZZ; Zhang, GX; Zhang, H | 1 |
| Pathak, AS; Rojas, M; Stouffer, GA | 1 |
| Daugherty, A; Franklin, MK; Howatt, DA; Lu, HS; Moorleghen, JJ; Mullick, AE; Ohno-Urabe, S; Sawada, H; Ye, D | 1 |
| Hu, X; Peng, L; Tang, R; Wang, W; Xiao, X; Zhang, L | 1 |
28 review(s) available for angiotensin ii and avapro
| Article | Year |
|---|---|
Angiotensin II receptor blockers. A new class of antihypertensive drugs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzothiadiazines; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diuretics; Enalapril; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Multicenter Studies as Topic; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride Symporter Inhibitors; Tetrazoles | 1996 |
Pharmacokinetic-pharmacodynamic relationships of three angiotensin II receptor antagonists in normal volunteers.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Prodrugs; Reference Values; Tetrazoles | 1996 |
Irbesartan. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in the management of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Hemodynamics; Humans; Hypertension; Irbesartan; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Tissue Distribution | 1997 |
Angiotensin II receptor pharmacology and AT1-receptor blockers.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes | 1999 |
Angiotensin-II receptor antagonists: their place in therapy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Drug Administration Schedule; Drug Interactions; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
Angiotensin II receptor antagonists in the treatment of hypertension.
Topics: Algorithms; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Receptors, Angiotensin; Telmisartan; Tetrazoles; Valine; Valsartan | 1999 |
[Antihypertensive advantages of angiotensin II AT1 receptor antagonism].
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Anti-Arrhythmia Agents; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Heart Diseases; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 1999 |
[Use of angiotensin II receptor blockaders in heart failure].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Heart Failure; Humans; Irbesartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2000 |
Angiotensin II antagonists for hypertension: are there differences in efficacy?
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Irbesartan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2000 |
Irbesartan: an updated review of its use in cardiovascular disorders.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cardiovascular Diseases; Humans; Irbesartan; Receptors, Angiotensin; Tetrazoles | 2000 |
Angiotensin receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Irbesartan; Losartan; Telmisartan; Tetrazoles | 2000 |
Putting the efficacy of candesartan cilexetil into perspective: a review of new comparative data.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cattle; Cerebellum; Circadian Rhythm; Female; Heart; Humans; Hypertension; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Middle Aged; Prodrugs; Rabbits; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin; Tetrazoles; Time Factors | 2000 |
Angiotensin II type 1 receptor blockers.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Drug Design; Humans; Irbesartan; Losartan; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles; Valine; Valsartan | 2001 |
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan | 2001 |
The protective effect of blocking angiotensin in both type I and type II diabetics with nephropathy.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Irbesartan; Losartan; Male; Middle Aged; Primary Prevention; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Tetrazoles; Treatment Outcome | 2001 |
[The effect of angiotensin-converting enzyme inhibitors on the progression of chronic renal failure].
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Clinical Trials as Topic; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Endothelins; Hemodynamics; Humans; Hypertension; Indoles; Irbesartan; Kidney; Kidney Failure, Chronic; Proteinuria; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Verapamil | 2002 |
Angiotensin receptor antagonists in patients with nephropathy due to type 2 diabetes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension, Renal; Irbesartan; Losartan; Renin-Angiotensin System; Tetrazoles | 2002 |
Angiotensin receptor blockers in diabetic nephropathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Diabetic Nephropathies; Humans; Irbesartan; Renin-Angiotensin System; Tetrazoles | 2001 |
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2 | 2003 |
Outcome studies in diabetic nephropathy.
Topics: Albuminuria; Anemia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hyperglycemia; Hyperlipidemias; Hypertension, Renal; Irbesartan; Kidney Failure, Chronic; Male; Outcome Assessment, Health Care; Proteinuria; Renin-Angiotensin System; Risk Factors; Smoking; Tetrazoles | 2003 |
Pharmacoeconomic aspects of losartan treatment to delay progression of renal disease in patients with Type 2 diabetes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Health Care Costs; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Treatment Outcome | 2003 |
Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence.
Topics: Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Proteinuria; Tetrazoles | 2003 |
Irbesartan: a review of its use in hypertension and in the management of diabetic nephropathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Randomized Controlled Trials as Topic; Tetrazoles | 2004 |
Role of angiotensin II receptor blockers in atherosclerotic plaque stability.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Biphenyl Compounds; Carotid Arteries; Collagen; Cyclooxygenase 2; Humans; Hypertension; Irbesartan; Macrophages; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Randomized Controlled Trials as Topic; Tetrazoles | 2006 |
Angiotensin II antagonists: clinical experience in the treatment of hypertension, prevention of cardiovascular outcomes and renal protection in diabetic nephropathy and proteinuria.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular System; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Kidney; Losartan; Proteinuria; Tetrazoles | 2006 |
Rational of the use of aliskiren in hypertension and beyond.
Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Europe; Fumarates; Germany; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Japan; Prevalence; Prorenin Receptor; Protein Precursors; Randomized Controlled Trials as Topic; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Risk Factors; Tetrazoles; Time Factors; World Health Organization | 2009 |
Differences in pharmacology and their translation into differences in clinical efficacy--a comparison of the renin angiotensin blocking agents irbesartan and losartan.
Topics: Administration, Oral; Angiotensin II; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Blood Pressure; Diabetic Nephropathies; Health Care Costs; Humans; Hypertension; Irbesartan; Losartan; Tetrazoles; Treatment Outcome | 2010 |
[Upstream approach for atrial fibrillation].
Topics: Amiodarone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Benzimidazoles; Biphenyl Compounds; Drug Therapy, Combination; Humans; Irbesartan; Tetrazoles | 2010 |
36 trial(s) available for angiotensin ii and avapro
| Article | Year |
|---|---|
Hemodynamic and biochemical effects of the AT1 receptor antagonist irbesartan in hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Body Weight; Catecholamines; Double-Blind Method; Electrolytes; Female; Hemodynamics; Humans; Hypertension; Irbesartan; Male; Middle Aged; Renin; Tetrazoles | 1995 |
[Interaction between SR 47436, a new angiotensin II antagonist and sympathetic nervous system in pithed SHR rats].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Decerebrate State; Drug Evaluation, Preclinical; Hemodynamics; Irbesartan; Male; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Tetrazoles | 1993 |
Dose-ranging study of the angiotensin II receptor antagonist irbesartan (SR 47436/BMS-186295) on blood pressure and neurohormonal effects in salt-deplete men.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Humans; Irbesartan; Male; Renin; Tetrazoles | 1996 |
Effect of high-performance liquid chromatography on plasma angiotensin II measurements in treated and untreated normotensive and hypertensive patients.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Chemical Analysis; Blood Pressure; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Hypertension; Irbesartan; Radioimmunoassay; Renin; Sensitivity and Specificity; Tetrazoles | 1997 |
Effects and tolerability of irbesartan versus enalapril in patients with severe hypertension. Irbesartan Multicenter Investigators.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Single-Blind Method; Tetrazoles | 1997 |
Acute renal effects of AT1-receptor blockade after exogenous angiotensin II infusion in healthy subjects.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dextrans; Double-Blind Method; Glomerular Filtration Rate; Humans; Irbesartan; Kidney; Male; Models, Biological; Potassium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reference Values; Renal Circulation; Renin; Sodium; Tetrazoles; Urea; Vasoconstriction | 1998 |
Pharmacokinetics and pharmacodynamics of irbesartan in patients with hepatic cirrhosis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Female; Humans; Irbesartan; Liver Cirrhosis; Male; Middle Aged; Renin; Tetrazoles | 1998 |
Oral bioavailability and disposition characteristics of irbesartan, an angiotensin antagonist, in healthy volunteers.
Topics: Administration, Oral; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Area Under Curve; Biological Availability; Biphenyl Compounds; Cross-Over Studies; Half-Life; Humans; Irbesartan; Male; Tetrazoles | 1998 |
Angiotensin II receptor blockade in normotensive subjects: A direct comparison of three AT1 receptor antagonists.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Irbesartan; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Time Factors; Valine; Valsartan | 1999 |
Time course and extent of angiotensin II antagonism after irbesartan, losartan, and valsartan in humans assessed by angiotensin II dose response and radioligand receptor assay.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Confounding Factors, Epidemiologic; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Losartan; Male; Radioligand Assay; Reference Values; Tetrazoles; Time Factors; Valine; Valsartan | 1999 |
Assessment of angiotensin II receptor blockade in humans using a standardized angiotensin II receptor-binding assay.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Irbesartan; Losartan; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 1999 |
Preliminary experience with the angiotensin II receptor antagonist irbesartan in chronic kidney disease.
Topics: Adolescent; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Child; Child, Preschool; Chronic Disease; Female; Humans; Irbesartan; Kidney Diseases; Male; Proteinuria; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2000 |
Opposing effects of angiotensin II on muscle and renal blood flow under euglycemic conditions.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Glucose; Cross-Over Studies; Double-Blind Method; Glomerular Filtration Rate; Glucose Clamp Technique; Humans; Irbesartan; Male; Muscle, Skeletal; Reference Values; Regional Blood Flow; Renal Circulation; Tetrazoles; Vasoconstrictor Agents | 2000 |
Inhibition of the acute effects of angiotensin II by the receptor antagonist irbesartan in normotensive men.
Topics: Adult; Aldosterone; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Heart Rate; Humans; Irbesartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regression Analysis; Renin; Tetrazoles | 2001 |
Vasoconstrictor effect of the angiotensin-converting enzyme-resistant, chymase-specific substrate [Pro(11)(D)-Ala(12)] angiotensin I in human dorsal hand veins: in vivo demonstration of non-ace production of angiotensin II in humans.
Topics: Administration, Oral; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chronic Disease; Chymases; Dose-Response Relationship, Drug; Double-Blind Method; Hand; Humans; Infusions, Intravenous; Irbesartan; Middle Aged; Peptidyl-Dipeptidase A; Reproducibility of Results; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction; Veins | 2001 |
[Effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes].
Topics: Adult; Aged; Albuminuria; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Irbesartan; Male; Middle Aged; Renin-Angiotensin System; Tetrazoles | 2001 |
Comparative angiotensin II receptor blockade in healthy volunteers: the importance of dosing.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2002 |
Pharmacodynamic studies on the angiotensin II type 1 antagonists irbesartan and candesartan based on angiotensin II dose response in humans.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Irbesartan; Male; Radioligand Assay; Receptor, Angiotensin, Type 1; Renin; Tetrazoles | 2002 |
[Effect of irbesartan, an antagonist of AT-1 receptors for angiotensin II, on L-arginine metabolism in arterial hypertension].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arginase; Arginine; Biphenyl Compounds; Blood Donors; Blood Pressure; Erythrocytes; Humans; Hypertension; Irbesartan; Nitric Oxide Synthase; Receptors, Angiotensin; Tetrazoles | 2002 |
Cardiovascular outcomes in the Irbesartan Diabetic Nephropathy Trial of patients with type 2 diabetes and overt nephropathy.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Placebos; Risk Factors; Tetrazoles; Treatment Outcome | 2003 |
Better renoprotective effect of angiotensin II antagonist compared to dihydropyridine calcium channel blocker in childhood.
Topics: Adolescent; Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Child; Creatinine; Cytoprotection; Female; Humans; Hypertension; Irbesartan; Kidney; Male; Serum Albumin; Tetrazoles | 2003 |
Kidney function during and after withdrawal of long-term irbesartan treatment in patients with type 2 diabetes and microalbuminuria.
Topics: Albuminuria; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Irbesartan; Kidney Function Tests; Male; Middle Aged; Placebos; Tetrazoles | 2003 |
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Collagen; Combined Modality Therapy; Cyclooxygenase 1; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endarterectomy, Carotid; Enzyme Induction; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Inflammation; Intramolecular Oxidoreductases; Irbesartan; Isoenzymes; Macrophages; Male; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Rupture, Spontaneous; Tetrazoles | 2004 |
Comparison of effects of losartan, irbesartan, and candesartan on flow-mediated brachial artery dilation and on inflammatory and thrombolytic markers in patients with systemic hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Brachial Artery; Double-Blind Method; Female; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Tetrazoles; Vasodilation | 2004 |
Effects of angiotensin-converting enzyme inhibitor plus irbesartan on maximal and submaximal exercise capacity and neurohumoral activation in patients with congestive heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Double-Blind Method; Drug Therapy, Combination; Enalapril; Exercise Tolerance; Female; Heart Failure; Humans; Irbesartan; Lactic Acid; Male; Middle Aged; Norepinephrine; Prospective Studies; Rest; Tetrazoles | 2005 |
[Clinical observation on treatment of IgA nephropathy with Huobahuagen Tablets and irbesartan].
Topics: Adolescent; Adult; Angiotensin II; Biphenyl Compounds; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Glomerulonephritis, IGA; Humans; Irbesartan; Male; Middle Aged; Phytotherapy; Tablets; Tetrazoles; Treatment Outcome | 2005 |
Effects of dual blockade of the renin angiotensin system in hypertensive type 2 diabetic patients with nephropathy.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Renin; Renin-Angiotensin System; Tetrazoles; Treatment Outcome | 2005 |
Angiotensin II does not affect endothelial tone in Type 1 diabetes-results of a double-blind placebo controlled trial.
Topics: Acetylcholine; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Female; Forearm; Humans; Indomethacin; Infusions, Intra-Arterial; Irbesartan; Male; Nitroprusside; omega-N-Methylarginine; Regional Blood Flow; Tetrazoles; Vasoconstriction; Vasodilator Agents | 2006 |
Effects of angiotensin receptor blockers on ambulatory plasma Renin activity in healthy, normal subjects during unrestricted sodium intake.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Biphenyl Compounds; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Olmesartan Medoxomil; Prognosis; Radioimmunoassay; Reference Values; Renin; Renin-Angiotensin System; Single-Blind Method; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan | 2007 |
A comparison of the efficacy and safety of irbesartan/HCTZ combination therapy with irbesartan and HCTZ monotherapy in the treatment of moderate hypertension.
Topics: Adult; Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2008 |
Effects of aerobic exercise training and irbesartan on blood pressure and heart rate variability in patients with chronic obstructive pulmonary disease.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography, Ambulatory; Exercise; Exercise Test; Exercise Therapy; Female; Follow-Up Studies; Forced Expiratory Volume; Heart Rate; Humans; Irbesartan; Male; Pilot Projects; Pulmonary Disease, Chronic Obstructive; Tetrazoles; Treatment Outcome | 2008 |
[Irbasartan in patients with hart failure and preserved left-ventricular systolic function. Results of the I-PRESERVE study].
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Female; Follow-Up Studies; Heart Failure; Humans; Irbesartan; Male; Retrospective Studies; Systole; Tetrazoles; Treatment Outcome; Ventricular Function, Left | 2009 |
The angiotensin II receptor type 2 polymorphism influences haemodynamic function and circulating RAS mediators in normotensive humans.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Female; Hemodynamics; Humans; Irbesartan; Kidney; Longitudinal Studies; Male; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors | 2010 |
Assessment of long-term effects of irbesartan on heart failure with preserved ejection fraction as measured by the minnesota living with heart failure questionnaire in the irbesartan in heart failure with preserved systolic function (I-PRESERVE) trial.
Topics: Aged; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Female; Follow-Up Studies; Heart Failure; Hospital Mortality; Humans; Irbesartan; Male; Minnesota; Stroke Volume; Surveys and Questionnaires; Survival Rate; Systole; Tetrazoles; Time Factors; Treatment Outcome; Ventricular Function, Left | 2012 |
Characterization of subgroups of heart failure patients with preserved ejection fraction with possible implications for prognosis and treatment response.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cause of Death; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heart Failure; Humans; Irbesartan; Male; Middle Aged; Prognosis; Prospective Studies; Stroke Volume; Survival Rate; Tetrazoles; United Kingdom; United States | 2015 |
Angiotensin II and the Natriuretic and Blood Pressure Response to Mental Stress in African Americans.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Black or African American; Blood Pressure; Cross-Over Studies; Diuretics; Double-Blind Method; Healthy Volunteers; Humans; Irbesartan; Male; Middle Aged; Renal Elimination; Sodium; Stress, Psychological | 2018 |
153 other study(ies) available for angiotensin ii and avapro
| Article | Year |
|---|---|
Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection | 1999 |
Effects of irbesartan (SR47436/BMS-186295) on angiotensin II-induced pressor responses in the pithed rat: potential mechanisms of action.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Time Factors | 1995 |
Studies of the renal effects of angiotensin II receptor blockade: the confounding factor of acute water loading on the action of vasoactive systems.
Topics: Adult; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Kidney; Kidney Tubules; Losartan; Natriuresis; Potassium; Renin-Angiotensin System; Sodium; Sodium, Dietary; Tetrazoles; Uric Acid; Vasomotor System; Water | 1995 |
Inhibition by BMS 186295, a selective nonpeptide AT1 antagonist, of adrenal catecholamine release induced by angiotensin II in the dog in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electrochemistry; Heart Rate; Irbesartan; Male; Tetrazoles | 1995 |
Repression of angiotensin II and potentiation of bradykinin contribute to the synergistic effects of dual metalloprotease inhibition in heart failure.
Topics: Alanine; Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Blood Volume; Bradykinin; Cricetinae; Drug Synergism; Enalaprilat; Heart Failure; Irbesartan; Male; Neprilysin; Tetrazoles; Vasodilation; Ventricular Function, Left | 1995 |
In vitro N-glucuronidation of SB 47436 (BMS 186295), a new AT1 nonpeptide angiotensin II receptor antagonist, by rat, monkey and human hepatic microsomal fractions.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Glucuronates; Glucuronosyltransferase; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Irbesartan; Isoenzymes; Macaca fascicularis; Male; Microsomes, Liver; Rats; Rats, Gunn; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Tetrazoles | 1994 |
A pharmacodynamic study of SR 47436, a selective AT1 receptor antagonist, on blood pressure in conscious cynomolgus monkeys.
Topics: Administration, Oral; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biological Availability; Biphenyl Compounds; Blood Pressure; Female; Heart Rate; Hypotension; Irbesartan; Macaca fascicularis; Male; Renin-Angiotensin System; Tetrazoles | 1994 |
Effect of SR 47436, a novel angiotensin II AT1 receptor antagonist, on human vascular smooth muscle cells in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Calcium; Cell Division; Cells, Cultured; Humans; Imidazoles; Iodine Radioisotopes; Irbesartan; Losartan; Mitogens; Muscle, Smooth, Vascular; Protein Binding; Tetrazoles | 1994 |
A new series of imidazolones: highly specific and potent nonpeptide AT1 angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Irbesartan; Macaca fascicularis; Male; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sensitivity and Specificity; Structure-Activity Relationship; Tetrazoles | 1993 |
Pharmacological study of SR 47436, a non-peptide angiotensin II AT1-receptor antagonist, in conscious monkeys.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Female; Imidazoles; Irbesartan; Losartan; Macaca fascicularis; Male; Renin; Sodium, Dietary; Tetrazoles | 1993 |
Angiotensin II modulates glomerular capillary permselectivity in rat isolated perfused kidney.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Capillaries; Capillary Permeability; Ficoll; Irbesartan; Kidney Glomerulus; Male; Metabolic Clearance Rate; Molecular Weight; Particle Size; Perfusion; Proteinuria; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles | 1996 |
Characterization of the AT1 angiotensin II receptor expressed in guinea pig liver.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Biphenyl Compounds; Enzyme Activation; Guinea Pigs; Imidazoles; Irbesartan; Liver; Losartan; Male; Polymerase Chain Reaction; Pyridines; Receptors, Angiotensin; RNA, Messenger; Tetrazoles | 1997 |
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan | 1997 |
Evaluation of the ability of irbesartan to cross the blood-brain barrier following acute intragastric treatment.
Topics: Adrenalectomy; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood-Brain Barrier; Carbachol; Drug Evaluation; Injections, Intraventricular; Irbesartan; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Stomach; Tetrazoles | 1998 |
Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotensin II antagonism.
Topics: Angiotensin II; Animals; Aorta; Arteritis; Biphenyl Compounds; Blotting, Western; Enzyme Inhibitors; Immunohistochemistry; Intercellular Adhesion Molecule-1; Irbesartan; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Tetrazoles; Vascular Cell Adhesion Molecule-1 | 1998 |
Comparison of irbesartan with captopril effects on cardiac hypertrophy and gene expression in heart failure-prone male SHHF/Mcc-fa(cp) rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Echocardiography; Gene Expression; Heart Failure; Irbesartan; Isoenzymes; Male; Myosin Heavy Chains; Organ Size; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; RNA, Messenger; Systole; Tetrazoles | 1999 |
Effects of systemic treatment with irbesartan and losartan on central responses to angiotensin II in conscious, normotensive rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Injections, Intravenous; Injections, Intraventricular; Irbesartan; Losartan; Male; Pituitary Gland, Posterior; Rats; Rats, Wistar; Tetrazoles; Vasopressins | 1999 |
[Drug clinics. Drug of the month. Irbesartan (Aprovel)].
Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Dose-Response Relationship, Drug; Half-Life; Humans; Hypertension; Irbesartan; Rabbits; Tetrazoles; Vasodilator Agents | 1999 |
AT1-receptor antagonists for the treatment of chronic heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Dogs; Heart Failure; Humans; Irbesartan; Losartan; Rats; Tetrazoles | 1999 |
Effects of long-term angiotensin II AT1 receptor blockade on survival, hemodynamics and cardiac remodeling in chronic heart failure in rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart Failure; Heart Rate; Irbesartan; Male; Rats; Rats, Wistar; Survival Rate; Tetrazoles; Vascular Resistance; Ventricular Pressure; Ventricular Remodeling | 1999 |
Mechanistic differences of various AT1-receptor blockers in isolated vessels of different origin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Proteins; Female; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Kinetics; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 1999 |
Insurmountable angiotensin AT1 receptor antagonists: the role of tight antagonist binding.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles | 1999 |
Torasemide inhibits angiotensin II-induced vasoconstriction and intracellular calcium increase in the aorta of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Calcium; Cells, Cultured; Endothelium, Vascular; Furosemide; Hypertension; Intracellular Membranes; Irbesartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Sulfonamides; Tetrazoles; Torsemide; Vasoconstriction | 1999 |
Comment on "Effects of long-term angiotensin II AT-1 receptor blockade on survival, hemodynamics and cardiac remodeling in chronic heart failure in rats".
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Chronic Disease; Heart Failure; Irbesartan; Rats; Tetrazoles | 1999 |
Disposition of irbesartan, an angiotensin II AT1-receptor antagonist, in mice, rats, rabbits, and macaques.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Area Under Curve; Bile; Biphenyl Compounds; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Feces; Female; Irbesartan; Liver; Macaca fascicularis; Macaca mulatta; Male; Mice; Mice, Inbred Strains; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Tetrazoles; Tissue Distribution | 2000 |
The angiotensin AT(1) receptor antagonist irbesartan has near-peptide affinity and potently blocks receptor signaling.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Dose-Response Relationship, Drug; Iodine Radioisotopes; Irbesartan; Kidney; Liver; Losartan; Male; PC12 Cells; Pituitary Gland; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1999 |
Angiotensin II and PDGF-BB stimulate beta(1)-integrin-mediated adhesion and spreading in human VSMCs.
Topics: Angiotensin II; Anticoagulants; Antigens, CD; Antihypertensive Agents; Aorta; Becaplermin; Biphenyl Compounds; Carcinogens; Cell Adhesion; Cell Movement; Collagen; Culture Techniques; Enzyme Inhibitors; Fibronectins; Flow Cytometry; Gene Expression; Genistein; Humans; Iliac Artery; Imidazoles; Integrin alpha5; Integrin beta1; Irbesartan; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrazoles; Vasoconstrictor Agents | 2000 |
Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts.
Topics: Actinin; Age Factors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antigens, CD; Antihypertensive Agents; Biphenyl Compounds; Cardiomegaly; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Collagen; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression; Heart Ventricles; Hydralazine; Imidazoles; Integrin alphaV; Integrin beta Chains; Integrin beta1; Integrin beta3; Integrins; Irbesartan; Laminin; Losartan; Myocardium; Phosphorylation; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Up-Regulation; Vitronectin | 2000 |
Vasoconstriction by in situ formed angiotensin II: role of ACE and chymase.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Child; Child, Preschool; Chymases; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Pyridines; Serine Endopeptidases; Swine; Tetrazoles; Vasoconstriction | 1999 |
Comparative effects of angiotensin II AT-1-type receptor antagonists in vitro on human platelet activation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Benzimidazoles; Benzoates; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Imidazoles; Irbesartan; Losartan; Platelet Activation; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Telmisartan; Tetrazoles; Thromboxane A2; Time Factors; Valine; Valsartan | 2000 |
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan | 2000 |
Synthesis and pharmacological evaluation of new pyrazolidine-3, 5-diones as AT(1) angiotensin II receptor antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Calcium; Humans; Irbesartan; Ligands; Pyrazoles; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Spiro Compounds; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured | 2000 |
Angiotensin II type 1 receptor antagonists. Why do some of them produce insurmountable inhibition?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding Sites; Biphenyl Compounds; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles | 2000 |
Influence of the angiotensin II AT1 receptor antagonist irbesartan on ischemia/reperfusion injury in the dog heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Coronary Circulation; Dogs; Heart; Hemodynamics; Injections, Intravenous; Irbesartan; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles | 2000 |
Endothelial dysfunction and oxidative stress during estrogen deficiency in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Endothelium, Vascular; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Free Radicals; Hypertension; Irbesartan; Ovariectomy; Oxidative Stress; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles; Up-Regulation | 2001 |
A two-state receptor model for the interaction between angiotensin II type 1 receptors and non-peptide antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; CHO Cells; Computer Simulation; Cricetinae; Dose-Response Relationship, Drug; Inositol Phosphates; Irbesartan; Kinetics; Losartan; Models, Biological; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2001 |
The mechanism of action of angiotensin II is dependent on direct activation of vascular smooth muscle carbonic anhydrase I.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Carbonic Anhydrases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Female; Humans; In Vitro Techniques; Irbesartan; Male; Middle Aged; Muscle, Smooth, Vascular; Tetrazoles | 2000 |
p38 Map kinase regulates vascular smooth muscle cell collagen synthesis by angiotensin II in SHR but not in WKY.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Collagen; Enzyme Activation; Hypertension; Imidazoles; Irbesartan; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Procollagen; Proline; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Thymidine | 2001 |
Prevention of hypertension by irbesartan in Dahl S rats relates to central angiotensin II type 1 receptor blockade.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Brain; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intraventricular; Injections, Subcutaneous; Irbesartan; Male; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles | 2001 |
The peripheral renin-angiotensin system is not involved in the hypertension of sheep exposed to prenatal dexamethasone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dexamethasone; Female; Glucocorticoids; Hypertension; Irbesartan; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sheep; Tetrazoles; Vasoconstrictor Agents | 2001 |
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor?
Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan | 2001 |
Angiotensin II type I receptor modulates intracellular free Mg2+ in renally derived cells via Na+-dependent Ca2+-independent mechanisms.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Amiloride; Angiotensin II; Animals; Antihypertensive Agents; Benzofurans; Biphenyl Compounds; Calcium; Calcium Channel Agonists; Cell Line; Cells, Cultured; Chelating Agents; Cytosol; Dogs; Dose-Response Relationship, Drug; Egtazic Acid; Ethers, Cyclic; Fluorescent Dyes; Fura-2; Imidazoles; Imipramine; Irbesartan; Kidney; Kinetics; Magnesium; Microscopy, Fluorescence; Peptides; Pyridines; Quinidine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium; Tetrazoles; Time Factors | 2001 |
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Captopril; Decerebrate State; Electric Stimulation; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Synaptic Transmission; Telmisartan; Tetrazoles | 2001 |
Beneficial effects on skeletal muscle of the angiotensin II type 1 receptor blocker irbesartan in experimental heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Biphenyl Compounds; Calcium Channel Blockers; Drug Evaluation, Preclinical; Gene Expression Regulation; Heart Failure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Infusion Pumps, Implantable; Irbesartan; Male; Monocrotaline; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Proteins; Muscle, Skeletal; Muscular Atrophy; Nifedipine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Tumor Necrosis Factor-alpha | 2001 |
Obese female SHHF/Mcc-fa(cp) rats resist antihypertensive effects of renin-angiotensin system inhibition.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Resistance; Female; Irbesartan; Obesity; Rats; Rats, Mutant Strains; Renin; Renin-Angiotensin System; Sex Characteristics; Tetrazoles; Thinness; Time Factors | 2001 |
Additive hypotensive and anti-albuminuric effects of angiotensin-converting enzyme inhibition and angiotensin receptor antagonism in diabetic spontaneously hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Drug Therapy, Combination; Gene Expression; Hypertension; Irbesartan; Kidney; Rats; Rats, Inbred SHR; Renin; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Effects of loop diuretics on angiotensin II-stimulated vascular smooth muscle cell growth.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Carrier Proteins; Cell Division; Cells, Cultured; Chlorides; Diuretics; Furosemide; Irbesartan; Leucine; Loop of Henle; Muscle, Smooth, Vascular; Potassium; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium; Sodium-Potassium-Chloride Symporters; Sulfonamides; Tetrazoles; Thymidine; Torsemide | 2001 |
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.
Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Biochemistry; Biphenyl Compounds; Drug Design; Imidazoles; Irbesartan; Losartan; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peptides, Cyclic; Rabbits; Structure-Activity Relationship; Tetrazoles; Thiophenes | 2001 |
Effect of the AT1-receptor antagonists losartan, irbesartan, and telmisartan on angiotensin II-induced facilitation of sympathetic neurotransmission in the rat mesenteric artery.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Irbesartan; Losartan; Male; Mesenteric Arteries; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sympathetic Nervous System; Telmisartan; Tetrazoles; Vasoconstrictor Agents | 2001 |
Insurmountable AT(1) receptor antagonism: the need for different antagonist binding states of the receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; CHO Cells; Cricetinae; Irbesartan; Phosphatidylinositols; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2001 |
Different types of antagonism by losartan and irbesartan on the effects of angiotensin II and its degradation products in rabbit arteries.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Antihypertensive Agents; Biphenyl Compounds; Endothelium, Vascular; Femoral Artery; Imidazoles; In Vitro Techniques; Irbesartan; Leucine; Losartan; Male; Peptides; Protease Inhibitors; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Renal Artery; Tetrazoles; Vasoconstrictor Agents | 2001 |
Impact of the renin-angiotensin system on cerebral perfusion following subarachnoid haemorrhage in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Heart Rate; Injections, Intraventricular; Intracranial Pressure; Irbesartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride; Subarachnoid Hemorrhage; Tetrazoles; Vasoconstrictor Agents | 2001 |
Angiotensin II-induced apoptosis in rat cardiomyocyte culture: a possible role of AT1 and AT2 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Apoptosis; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cells, Cultured; Heart; Intracellular Membranes; Irbesartan; Myocardium; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Verapamil | 2001 |
Renal protection by angiotensin II receptor antagonists in patients with type 2 diabetes.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Hypertension, Renal; Irbesartan; Kidney; Losartan; Male; Primary Prevention; Prognosis; Tetrazoles; Treatment Outcome | 2001 |
AT(2) receptor-mediated vasodilation in the heart: effect of myocardial infarction.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Cardiac Output; Coronary Circulation; Heart Failure; Heart Rate; Imidazoles; Irbesartan; Male; Myocardial Infarction; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Survival Rate; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2001 |
Vasoconstriction is determined by interstitial rather than circulating angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Carotid Arteries; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Irbesartan; Isoquinolines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Increased osteopontin expression following renal ablation is attenuated by angiotensin type 1 receptor antagonism.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cell Division; Immunohistochemistry; In Situ Hybridization; Irbesartan; Kidney; Leukocytes, Mononuclear; Macrophages; Male; Nephrectomy; Osteopontin; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renal Insufficiency; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Transcriptional Activation | 2002 |
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Biological Availability; Biphenyl Compounds; Blood Pressure; Blood Vessels; Disease Models, Animal; Drug Therapy, Combination; Female; Hypertension; Immunohistochemistry; Irbesartan; Male; Membrane Transport Proteins; NADPH Dehydrogenase; NADPH Oxidases; Nitric Oxide; Phosphoproteins; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Stroke; Superoxides; Tetrazoles | 2002 |
[Angiotensin 2 receptor blockaders: how do we explain the kidney-protective effect?].
Topics: Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Irbesartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Tetrazoles | 2002 |
[Diabetic patient with hypertension takes A-I I blocker. Less likely dialysis].
Topics: Albuminuria; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Clinical Trials as Topic; Diabetes Complications; Diabetic Nephropathies; Humans; Hypertension; Irbesartan; Risk Factors; Tetrazoles | 2002 |
Vasopressin-induced presynaptic facilitation of sympathetic neurotransmission in the pithed rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Irbesartan; Male; Norepinephrine; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 2002 |
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors.
Topics: Adipocytes; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Biphenyl Compounds; Captopril; Cell Differentiation; Cells, Cultured; Coculture Techniques; Gene Expression; Humans; Irbesartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Renin-Angiotensin System; Stem Cells; Tetrazoles; Transcription Factors | 2002 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bosentan; Calcium Channel Blockers; Collagen; Dansyl Compounds; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Immunohistochemistry; Irbesartan; Male; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles | 2002 |
In vitro and in vivo characterization of the activity of telmisartan: an insurmountable angiotensin II receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Cell Membrane; In Vitro Techniques; Irbesartan; Kinetics; Muscle, Smooth, Vascular; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles | 2002 |
Sympatholytic properties of several AT1-receptor antagonists in the isolated rabbit thoracic aorta.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Benzimidazoles; Benzoates; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Irbesartan; Losartan; Norepinephrine; Osmolar Concentration; Rabbits; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Sympatholytics; Synaptic Transmission; Telmisartan; Tetrazoles | 2002 |
Antagonist interaction with endogenous AT(1) receptors in human cell lines.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Cell Line; CHO Cells; Cricetinae; Humans; Inositol Phosphates; Iodine Radioisotopes; Irbesartan; Muscle, Smooth, Vascular; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Transfection | 2002 |
Comparison of 3D structures and AT(1) binding properties of pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones with parent antihypertensive drug irbesartan.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Crystallography, X-Ray; Humans; Irbesartan; Models, Molecular; Pyrazoles; Pyridazines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Structure-Activity Relationship; Tetrazoles; Tumor Cells, Cultured | 2002 |
Control of dendritic cell differentiation by angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dendritic Cells; Endocytosis; Hematopoietic Stem Cells; Humans; Irbesartan; Losartan; Lymphocyte Activation; Mice; Models, Biological; Monocytes; Phenotype; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles | 2003 |
Involvement of the AT(2)-receptor in angiotensin II-induced facilitation of sympathetic neurotransmission.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Imidazoles; Irbesartan; Male; Norepinephrine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Saralasin; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles | 2002 |
Sympatho-inhibitory actions of irbesartan in pithed spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hypertension; Irbesartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Species Specificity; Sympathetic Nervous System; Sympatholytics; Tetrazoles | 2003 |
Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Bosentan; Cardiomyopathies; Dansyl Compounds; Disease Models, Animal; Endothelin-1; Fibrosis; Hypertension; Irbesartan; Male; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Sulfonamides; Tetrazoles; Time Factors; Vasoconstrictor Agents | 2003 |
Induction of MIF synthesis and secretion by tubular epithelial cells: a novel action of angiotensin II.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; In Vitro Techniques; Irbesartan; Kidney Tubules; Macrophage Migration-Inhibitory Factors; Macrophages; Nephrectomy; Rats; Rats, Sprague-Dawley; RNA, Messenger; T-Lymphocytes; Tetrazoles; Vasoconstrictor Agents | 2003 |
Summaries for patients. Effects of blood pressure drugs in patients with diabetes and kidney disease.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Placebos; Risk Factors; Tetrazoles; Treatment Outcome | 2003 |
No involvement of the AT2-receptor in angiotensin II-enhanced sympathetic transmission in vitro.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Synergism; Electric Stimulation; Imidazoles; In Vitro Techniques; Irbesartan; Male; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Tritium; Vasoconstrictor Agents; Vena Cava, Inferior | 2003 |
Functional comparison of the antagonistic properties of some Angiotensin II type 1 receptor blockers on the contraction elicited by Angiotensin II and thromboxane A2 on human saphenous veins.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Drug Antagonism; Humans; Imidazoles; In Vitro Techniques; Irbesartan; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Thromboxane A2, Prostaglandin H2; Saphenous Vein; Tetrazoles; Valine; Valsartan | 2003 |
Study of the hypothalamic angiotensin system in aortic coarctated rats using the reverse microdialysis technique.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aortic Coarctation; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Hydroxyindoleacetic Acid; Hypothalamus, Anterior; Hypothalamus, Posterior; Irbesartan; Male; Microdialysis; Perfusion; Rats; Rats, Wistar; Receptors, Angiotensin; Serotonin; Tetrazoles | 2003 |
Asynchronous development of electrical remodeling and cardiac hypertrophy in the complete AV block dog.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Bradycardia; Chymases; Dose-Response Relationship, Drug; Female; Heart Block; Humans; Hypertrophy, Left Ventricular; Irbesartan; Male; Peptidyl-Dipeptidase A; Phenethylamines; Potassium Channel Blockers; Serine Endopeptidases; Sulfonamides; Tetrazoles; Torsades de Pointes | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
Pharmacokinetics and the cardiovascular effects of irbesartan in aortic coarctated rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Aortic Coarctation; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Female; Heart Rate; Hypothalamus, Anterior; Injections, Intraperitoneal; Injections, Intravenous; Irbesartan; Metabolic Clearance Rate; Microdialysis; Protein Binding; Rats; Rats, Wistar; Tetrazoles; Time Factors; Tissue Distribution | 2004 |
[Renal protective effect of angiotensin II receptor antagonist on growth hormone-treated nephrotic rats].
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibiotics, Antineoplastic; Biphenyl Compounds; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Disease Models, Animal; Doxorubicin; Fibronectins; Growth Hormone; Immunohistochemistry; Irbesartan; Kidney Diseases; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Serum Albumin; Tetrazoles; Transforming Growth Factor beta; Triglycerides | 2003 |
Effect of irbesartan on angiotensin II-induced hypertrophy of human proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cell Cycle; Cells, Cultured; Humans; Hypertrophy; Irbesartan; Kidney Tubules, Proximal; Protein Biosynthesis; Tetrazoles | 2004 |
Angiotensin II type 2 receptor-mediated vasodilation in human coronary microarteries.
Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Biphenyl Compounds; Child; Child, Preschool; Coronary Circulation; Coronary Vessels; Cyclic GMP; Female; Humans; Imidazoles; Irbesartan; Male; Microcirculation; Middle Aged; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; RNA, Messenger; Tetrazoles; Vasodilation | 2004 |
Mesenteric artery remodeling and effects of imidapril and irbesartan on it in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Female; Humans; Imidazolidines; Irbesartan; Male; Mesenteric Arteries; Proto-Oncogene Proteins c-jun; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Flavonoids; Irbesartan; Leucine; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Signal Transduction; Sirolimus; Tetrazoles | 2004 |
Osteoprotegerin and osteopontin are expressed at high concentrations within symptomatic carotid atherosclerosis.
Topics: Aged; Angiotensin II; Arteriosclerosis; Biphenyl Compounds; Blotting, Western; Carotid Stenosis; Carrier Proteins; Culture Techniques; Female; Glycoproteins; Humans; Immunohistochemistry; Irbesartan; Male; Membrane Glycoproteins; Middle Aged; Osteopontin; Osteoprotegerin; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Tetrazoles; Up-Regulation | 2004 |
Effects of angiotensin II receptor blocker (irbesartan) on peritoneal membrane functions.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biological Transport; Biphenyl Compounds; Blood Pressure; Creatinine; Female; Humans; Irbesartan; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Peritoneum; Prealbumin; Proteins; Serum Albumin; Tetrazoles; Transferrin | 2004 |
AT-1 receptor antagonism modifies the mediation of endothelin-1, thromboxane A2, and catecholamines in the renal constrictor response to angiotensin II.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biphenyl Compounds; Catecholamines; Dose-Response Relationship, Drug; Endothelin-1; Irbesartan; Male; Potassium Chloride; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Renal Circulation; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents | 2005 |
Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Dogs; Endothelin A Receptor Antagonists; Humans; Hypertension; Irbesartan; Isoxazoles; Macaca fascicularis; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Structure-Activity Relationship; Sulfonamides; Tetrazoles | 2005 |
Enhanced angiotensin II-mediated effects in fibroblasts of patients with familial hypercholesterolemia.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arteriosclerosis; Biphenyl Compounds; Calcium; Case-Control Studies; Cell Proliferation; Cells, Cultured; Cholesterol, LDL; Dose-Response Relationship, Drug; Endothelin-1; Female; Fibroblasts; Heterozygote; Humans; Hyperlipoproteinemia Type II; Irbesartan; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Middle Aged; Receptor, Angiotensin, Type 1; Tetrazoles; Transforming Growth Factor beta | 2005 |
Effect of high glucose on superoxide in human mesangial cells: role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Cell Culture Techniques; Diabetic Nephropathies; Glucose; Humans; Irbesartan; Kidney Glomerulus; Losartan; Oxidants; Superoxide Dismutase; Superoxides; Tetrazoles | 2005 |
Failure of angiotensin II to suppress plasma renin activity in normotensive subjects with a positive family history of hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Hypertension; Irbesartan; Male; Renal Circulation; Renin; Renin-Angiotensin System; Sodium; Tetrazoles | 2005 |
PPARgamma-activating angiotensin type-1 receptor blockers induce adiponectin.
Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cycloheximide; Insulin Resistance; Irbesartan; Mice; Obesity; PPAR gamma; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Telmisartan; Tetrazoles | 2005 |
Association of osteoprotegerin with human abdominal aortic aneurysm progression.
Topics: Adult; Aged; Angiotensin II; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis; Biopsy; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Disease Progression; Gene Expression Regulation, Enzymologic; Glycoproteins; Humans; Irbesartan; Male; Matrix Metalloproteinase 9; Middle Aged; Muscle, Smooth, Vascular; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Tetrazoles; Ultrasonography | 2005 |
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome | 2005 |
Novel polymer monolith microextraction using a poly(methacrylic acid-ethylene glycol dimethacrylate) monolith and its application to simultaneous analysis of several angiotensin II receptor antagonists in human urine by capillary zone electrophoresis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Electrophoresis, Capillary; Ethylene Glycols; Humans; Irbesartan; Losartan; Methacrylates; Receptors, Angiotensin; Sensitivity and Specificity; Telmisartan; Tetrazoles | 2006 |
Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(mREN2)27 rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biological Transport; Biphenyl Compounds; Glucose; Glucose Transporter Type 4; Glycogen Synthase; Hypertension; Insulin Receptor Substrate Proteins; Insulin Resistance; Irbesartan; Male; Mice; Muscle, Skeletal; Phosphoproteins; Rats; Renin; Tetrazoles | 2005 |
Connective tissue growth factor-mediated angiotensin II-induced hypertrophy of proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cell Cycle; Cell Line; Cells, Cultured; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Humans; Hypertrophy; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Irbesartan; Kidney; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles | 2006 |
Teratogenicity with angiotensin II receptor antagonists in pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Diabetes Mellitus, Type 1; Female; Humans; Irbesartan; Kidney; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Tetrazoles | 2005 |
Lichenoid drug eruption due to an antihypertonic drug containing irbesartan and hydrochlorothiazide.
Topics: Aged; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Drug Combinations; Drug Eruptions; Female; Humans; Hydrochlorothiazide; Irbesartan; Lichenoid Eruptions; Tetrazoles | 2006 |
Carvedilol-induced antagonism of angiotensin II: a matter of alpha1-adrenoceptor blockade.
Topics: Adolescent; Adrenergic Antagonists; Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Carbazoles; Carvedilol; Coronary Vessels; Female; Humans; Inositol Phosphates; Irbesartan; Luciferases; Male; Metoprolol; Middle Aged; Myography; Propanolamines; Signal Transduction; Tetrazoles | 2006 |
Coronary vasoconstrictor influence of angiotensin II is reduced in remodeled myocardium after myocardial infarction.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Body Weight; Coronary Circulation; Exercise Test; Female; Irbesartan; Male; Myocardial Infarction; Myocardium; Norepinephrine; Organ Size; Oxygen; Physical Conditioning, Animal; Sus scrofa; Tetrazoles; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasomotor System | 2006 |
Irbesartan restores the in-vivo insulin signaling pathway leading to Akt activation in obese Zucker rats.
Topics: Adaptor Proteins, Signal Transducing; Analysis of Variance; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fatty Liver; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Irbesartan; Male; Mitogen-Activated Protein Kinase 3; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptor, Insulin; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tetrazoles | 2006 |
Role of TGF-beta1 in vascular smooth muscle cell apoptosis induced by angiotensin II.
Topics: Activin Receptors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Benzamides; Biphenyl Compounds; Cell Proliferation; Cells, Cultured; Dioxoles; Irbesartan; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta1 | 2007 |
Angiotensin II-mediated oxidative stress and inflammation mediate the age-dependent cardiomyopathy in ACE2 null mice.
Topics: Adaptor Proteins, Signal Transducing; Aging; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Blotting, Western; Cardiomyopathy, Dilated; Class Ib Phosphatidylinositol 3-Kinase; Irbesartan; Isoenzymes; Luminescent Measurements; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Oxidative Stress; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles | 2007 |
Importance of intracellular angiotensin II in vascular smooth muscle cell apoptosis: inhibition by the angiotensin AT1 receptor antagonist irbesartan.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Arsenicals; Biphenyl Compounds; Blotting, Western; Caspase 3; DNA Fragmentation; Flow Cytometry; Fluorescent Antibody Technique; Imidazoles; Irbesartan; Male; Muscle, Smooth, Vascular; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Tetrazoles; Transfection | 2007 |
ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats.
Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Disease Models, Animal; Fatty Liver; Interleukin-6; Irbesartan; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Obesity; Perindopril; Rats; Rats, Zucker; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2008 |
Integrative control of coronary resistance vessel tone by endothelin and angiotensin II is altered in swine with a recent myocardial infarction.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Hemodynamics; Irbesartan; Myocardial Infarction; Oxygen; Physical Exertion; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Tetrazoles; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Ventricular Function, Left; Ventricular Remodeling | 2008 |
Systemic and local effects of angiotensin II blockade in experimental diabetic nephropathy.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Immunohistochemistry; Irbesartan; Kidney Glomerulus; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2008 |
Central estrogen inhibition of angiotensin II-induced hypertension in male mice and the role of reactive oxygen species.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Data Interpretation, Statistical; Estradiol; Estrogens; Fulvestrant; Hypertension; Injections, Intraventricular; Irbesartan; Male; Mice; Microscopy, Confocal; Oxidative Stress; Reactive Oxygen Species; Spin Labels; Subfornical Organ; Telemetry; Tetrazoles | 2008 |
Irbesartan attenuates Ang II-induced BMP-2 expression in human umbilical vein endothelial cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Bone Morphogenetic Protein 2; Cells, Cultured; Culture Media; Drug Interactions; Endothelial Cells; Gene Expression; Humans; Irbesartan; Malondialdehyde; Superoxide Dismutase; Tetrazoles; Transcription Factor RelA; Umbilical Veins; Vasoconstrictor Agents | 2008 |
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Disease Models, Animal; Flavonoids; Irbesartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling | 2008 |
Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta, Thoracic; Biphenyl Compounds; Diabetes Mellitus, Experimental; In Vitro Techniques; Irbesartan; Losartan; Male; Rats; Rats, Wistar; rho-Associated Kinases; Tetrazoles; Up-Regulation; Vasoconstriction | 2009 |
Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Irbesartan; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptor, Angiotensin, Type 1; RNA, Messenger; Superoxides; Tetrazoles; Time Factors; Ultrasonography; Ventricular Remodeling | 2009 |
Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat.
Topics: Albuminuria; Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Fumarates; Glomerular Filtration Rate; Hypertension; Irbesartan; Kidney; Membrane Glycoproteins; Membrane Proteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Podocytes; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Tyrosine | 2010 |
Effects of angiotensin metabolites in the coronary vascular bed of the spontaneously hypertensive rat: loss of angiotensin II type 2 receptor-mediated vasodilation.
Topics: Analysis of Variance; Angiotensin II; Angiotensin III; Animals; Aorta, Abdominal; Biphenyl Compounds; Coronary Circulation; Disease Models, Animal; Iliac Artery; Imidazoles; Irbesartan; Male; Probability; Pyridines; Random Allocation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 2; Reference Values; Tetrazoles; Vasoconstriction; Vasodilation | 2010 |
The inhibitory effects of rosiglitazone on cardiac hypertrophy through modulating the renin-angiotensin system in diet-induced hypercholesterolemic rats.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Cardiomegaly; Cholesterol, Dietary; Hypercholesterolemia; Irbesartan; Male; Myocardium; PPAR gamma; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Rosiglitazone; Tetrazoles; Thiazolidinediones | 2010 |
Involvement of the renin-angiotensin system in the development of vascular damage in a rat model of arthritis: effect of angiotensin receptor blockers.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arthritis, Experimental; Biphenyl Compounds; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Hypertrophy; Irbesartan; Losartan; Male; Oxidative Stress; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Risk Reduction Behavior; Tetrazoles; Vasoconstrictor Agents | 2010 |
Integrated control of pulmonary vascular tone by endothelin and angiotensin II in exercising swine depends on gender.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Endothelin Receptor Antagonists; Endothelins; Female; Irbesartan; Male; Models, Animal; Physical Conditioning, Animal; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Endothelin; Sex Characteristics; Swine; Tetrazoles; Vasoconstriction; Vasodilator Agents | 2010 |
A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity.
Topics: Alanine; Angiotensin II; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Chlorocebus aethiops; COS Cells; Humans; Imidazoles; Inositol Phosphates; Irbesartan; Losartan; Polymorphism, Single Nucleotide; Receptor, Angiotensin, Type 1; Telmisartan; Tetrazoles; Threonine; Valine; Valsartan | 2010 |
Angiotensin II contributes to the increased baseline leg vascular resistance in spinal cord-injured individuals.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Case-Control Studies; Humans; Irbesartan; Leg; Male; Middle Aged; Spinal Cord Injuries; Supine Position; Tetrazoles; Vascular Resistance | 2010 |
Angiotensin II mediates the high-glucose-induced endothelial-to-mesenchymal transition in human aortic endothelial cells.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aorta; Biphenyl Compounds; Calcium-Binding Proteins; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Glucose; Humans; Irbesartan; Mesoderm; Renin-Angiotensin System; RNA, Messenger; S100 Calcium-Binding Protein A4; Tetrazoles | 2010 |
Irbesartan inhibits advanced glycation end product (AGE)-induced up-regulation of vascular cell adhesion molecule-1 (VCAM-1) mRNA levels in glomerular endothelial cells.
Topics: Acetylcysteine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Biphenyl Compounds; Cells, Cultured; Endothelial Cells; Gene Expression; Glycation End Products, Advanced; Humans; Hydrogen Peroxide; Irbesartan; Kidney Glomerulus; Peptidyl-Dipeptidase A; Renin; Salicylates; Serum Albumin, Bovine; Superoxides; Tetrazoles; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2011 |
20-Hydroxyeicosatetraenoic acid synthesis is increased in human neutrophils and platelets by angiotensin II and endothelin-1.
Topics: Adult; Aged; Amidines; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Platelets; Calcium Channels; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Endothelin-1; Humans; Hydroxyeicosatetraenoic Acids; Imidazoles; Ionophores; Irbesartan; Male; Middle Aged; Neutrophils; Oligopeptides; Peptides, Cyclic; Piperidines; Pyridines; Tetrazoles; Young Adult | 2011 |
[Effect of irbesartan of the function of hemocoagulative component of hemostasis in patients with arterial hypertension during metabolic syndrome].
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Blood Pressure; Female; Follow-Up Studies; Hemostasis; Humans; Hypertension; Irbesartan; Male; Metabolic Syndrome; Middle Aged; Tetrazoles; Treatment Outcome | 2010 |
Endothelial microparticle formation by angiotensin II is mediated via Ang II receptor type I/NADPH oxidase/ Rho kinase pathways targeted to lipid rafts.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Biphenyl Compounds; Blood Pressure; Cell-Derived Microparticles; Cells, Cultured; Endothelial Cells; Hypertrophy, Left Ventricular; Irbesartan; Male; Membrane Microdomains; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; NADPH Oxidases; Platelet Endothelial Cell Adhesion Molecule-1; Protein Kinase Inhibitors; Reactive Oxygen Species; rho-Associated Kinases; Signal Transduction; Tetrazoles; Vascular Cell Adhesion Molecule-1 | 2011 |
Novel mechanism of salt-induced glomerular injury: critical role of eNOS and angiotensin II.
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Biphenyl Compounds; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Glomerulonephritis; Irbesartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidative Stress; Sodium Chloride, Dietary; Spin Labels; Tetrazoles | 2011 |
[Activation of Rho-kinase pathway is involved in angiotensin II-induced contraction of human airway smooth muscle cells].
Topics: Amides; Angiotensin II; Asthma; Biphenyl Compounds; Bronchi; Humans; Irbesartan; Muscle Contraction; Muscle, Smooth; Primary Cell Culture; Pyridines; rho-Associated Kinases; Signal Transduction; Tetrazoles | 2011 |
Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Biphenyl Compounds; Blood Pressure; Blotting, Western; Capillaries; Cells, Cultured; Cyclic N-Oxides; Endothelial Cells; Heart Diseases; Hydralazine; Hypertension; Hypertrophy, Left Ventricular; Immunohistochemistry; Irbesartan; MAP Kinase Kinase Kinase 5; Myocardial Ischemia; Oxidative Stress; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Spin Labels; Superoxides; Tetrazoles; Ultrasonography; Vascular Endothelial Growth Factor A | 2012 |
Angiotensin II receptor type 1 blockers suppress the cell proliferation effects of angiotensin II in breast cancer cells by inhibiting AT1R signaling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; CREB-Binding Protein; Cyclin D1; Female; Humans; Irbesartan; Mitogen-Activated Protein Kinases; NF-kappa B; Proliferating Cell Nuclear Antigen; raf Kinases; ras Proteins; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Signal Transduction; Tetrazoles; Tumor Suppressor Protein p53 | 2012 |
Irbesartan and emodin on myocardial remodeling in Goldblatt hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Connective Tissue Growth Factor; Drug Therapy, Combination; Emodin; Gene Expression Regulation; Hypertension; Irbesartan; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta1; Ventricular Remodeling | 2012 |
Effects of irbesartan on gene expression revealed by transcriptome analysis of left atrial tissue in a porcine model of acute rapid pacing in vivo.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Biphenyl Compounds; Blotting, Western; Cell Line; Connective Tissue Growth Factor; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Heart Atria; Heart Rate; Irbesartan; Mice; Microarray Analysis; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Tetrazoles | 2013 |
Role of the angiotensin converting enzyme 1/angiotensin II/angiotensin receptor 1 axis in interstitial collagenase expression in human carotid atheroma.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Carotid Artery Diseases; Collagenases; Dipeptides; Elastin; Endarterectomy, Carotid; Extracellular Matrix; Humans; Irbesartan; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 8; Matrix Metalloproteinase Inhibitors; Organ Culture Techniques; Peptides; Peptidyl-Dipeptidase A; Plaque, Atherosclerotic; Quinapril; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrahydroisoquinolines; Tetrazoles | 2013 |
Angiotensin-(1-7) protects from experimental acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electric Impedance; Endothelial Cells; Hemodynamics; Imidazoles; Irbesartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Respiratory Mechanics; Tetrazoles | 2013 |
Exposure of cardiomyocytes to angiotensin II induces over-activation of monoamine oxidase type A: implications in heart failure.
Topics: Aldehyde Dehydrogenase; Angiotensin II; Animals; Biphenyl Compounds; Catalase; Enzyme Activation; Heart Failure; Hyperglycemia; Irbesartan; Losartan; Monoamine Oxidase; Myocytes, Cardiac; Rats; Tetrazoles | 2013 |
Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Cardiomegaly; Cardiotonic Agents; Collagen; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Gene Expression Regulation; Irbesartan; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; PPAR alpha; PPAR delta; PPAR gamma; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Tetrazoles; Transforming Growth Factor beta | 2013 |
Calcitriol supplementation improves endothelium-dependent vasodilation in rat hypertensive renal injury.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Calcitriol; Dietary Supplements; Dinoprost; Disease Models, Animal; Endothelium, Vascular; Glucuronidase; Hypertension; Irbesartan; Kidney; Kidney Diseases; Klotho Proteins; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Tetrazoles; Vasodilation; Vitamins | 2014 |
Effects of emodin and irbesartan on ventricular fibrosis in Goldblatt hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blotting, Western; Cardiomyopathies; Collagen; Echocardiography; Emodin; Enzyme Inhibitors; Fibrosis; Heart Ventricles; Hydroxyproline; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Irbesartan; Male; Matrix Metalloproteinase 2; Myocardium; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; RNA, Messenger; Tetrazoles | 2014 |
Medical treatment of an adult with uncorrected isolated interrupted aorta resulted in no complications after 4 years of follow-up.
Topics: Angiography; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aorta, Thoracic; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Irbesartan; Middle Aged; Multidetector Computed Tomography; Tetrazoles; Time Factors; Vascular Malformations | 2014 |
Comparison of calycosin and irbesartan for their impact on renin angiotensin system in human umbilical vein endothelial cell.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Biphenyl Compounds; Cells, Cultured; Human Umbilical Vein Endothelial Cells; Humans; Irbesartan; Isoflavones; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Tetrazoles | 2015 |
Retinal ganglion cell neuroprotection by an angiotensin II blocker in an ex vivo retinal explant model.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blotting, Western; Cell Count; Dendrites; Imaging, Three-Dimensional; Irbesartan; Male; Membrane Glycoproteins; Models, Biological; NADP; NADPH Oxidase 2; NADPH Oxidases; Neuroprotection; Protein Subunits; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 2; Retinal Ganglion Cells; RNA, Messenger; Staining and Labeling; Tetrazoles | 2015 |
Angiotensin Ⅱ Activates MCP-1 and Induces Cardiac Hypertrophy and Dysfunction via Toll-like Receptor 4.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cardiomegaly; Chemokine CCL2; Hypertension; Irbesartan; Male; Mice; Mice, Inbred BALB C; Norepinephrine; Oxidative Stress; Tetrazoles; Toll-Like Receptor 4; Vasoconstrictor Agents | 2015 |
TLR4 is a critical regulator of angiotensin II-induced vascular remodeling: the roles of extracellular SOD and NADPH oxidase.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Blood Pressure; Blood Vessels; Chemokine CCL2; Irbesartan; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; NADPH Oxidases; Norepinephrine; Reactive Oxygen Species; Superoxide Dismutase; Tetrazoles; Toll-Like Receptor 4; Vasoconstrictor Agents | 2015 |
Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cell Line; Disease Models, Animal; DNA Methylation; Dose-Response Relationship, Drug; Doxorubicin; Epigenesis, Genetic; Irbesartan; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Podocytes; Promoter Regions, Genetic; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Tetrazoles; Time Factors; Transfection | 2015 |
Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-γ), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats.
Topics: Adiponectin; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Gene Expression Regulation; Heart Rate; Hemodynamics; Hypertension; Injections, Intraperitoneal; Irbesartan; Kidney; Male; Methoxamine; Norepinephrine; Phenylephrine; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, alpha; Signal Transduction; Tetrazoles; Vasoconstrictor Agents; Vasodilator Agents | 2016 |
The Interplay between the Renin Angiotensin System and Pacing Postconditioning Induced Cardiac Protection.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Cardiac Pacing, Artificial; Heart; Hemodynamics; Irbesartan; Male; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 2016 |
[Irbesartan ameliorates cardiac inflammation in type 2 diabetic db/db mice].
Topics: Actins; Angiotensin II; Animals; Biphenyl Compounds; Cardiovascular Diseases; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Inflammation; Interleukin-6; Irbesartan; Mice; Obesity; Random Allocation; Real-Time Polymerase Chain Reaction; Signal Transduction; Tetrazoles; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
Dose-Effect of Irbesartan on Cyclooxygenase-2 and Matrix Metalloproteinase-9 Expression in Rabbit Atherosclerosis.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Aortic Diseases; Atherosclerosis; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Irbesartan; Lipids; Male; Matrix Metalloproteinase 9; NF-kappa B; Plaque, Atherosclerotic; Rabbits; Signal Transduction | 2018 |
Irbesartan may relieve renal injury by suppressing Th22 cells chemotaxis and infiltration in Ang II-induced hypertension.
Topics: Angiotensin II; Animals; Cell Differentiation; Cell Survival; Chemotaxis; Cytokines; Hypertension; Irbesartan; Kidney; Male; Mice, Inbred C57BL; T-Lymphocytes; T-Lymphocytes, Helper-Inducer | 2020 |
RhoA/ROCK Pathway Activation is Regulated by AT1 Receptor and Participates in Smooth Muscle Migration and Dedifferentiation via Promoting Actin Cytoskeleton Polymerization.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actin Cytoskeleton; Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Dedifferentiation; Cell Line; Cell Movement; Gene Expression Regulation; Humans; Irbesartan; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Polymerization; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 1; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Small Interfering; Signal Transduction; Vasodilator Agents | 2020 |
Antihypertensive properties of a traditional Chinese medicine GAO-ZI-YAO in elderly spontaneous hypertensive rats.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Cytokines; Drugs, Chinese Herbal; Endothelin-1; Hypertension; Irbesartan; Male; Medicine, Chinese Traditional; Nitric Oxide; Rats; Rats, Inbred SHR; Vascular Endothelial Growth Factor A | 2020 |
Expression of Cyr61 in ApoE
Topics: Amides; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Blood Pressure; Cysteine-Rich Protein 61; Fumarates; Gene Expression Regulation; Humans; Hypertension; Irbesartan; Mice; Mice, Knockout; Renal Artery; Renal Artery Obstruction | 2021 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupture; Dilatation, Pathologic; Disease Models, Animal; Irbesartan; Losartan; Lysine; Male; Mice; Mice, Inbred C57BL; Protein-Lysine 6-Oxidase; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2022 |
Expression of LRG-1 in mice with hypertensive renal damage and its significance.
Topics: Angiotensin II; Animals; Collagen Type I; Creatinine; Fibronectins; Hypertension; Irbesartan; Kidney; Mice; Mice, Inbred C57BL | 2023 |