angiotensin ii has been researched along with angiotensinogen in 777 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 176 (22.65) | 18.7374 |
| 1990's | 184 (23.68) | 18.2507 |
| 2000's | 230 (29.60) | 29.6817 |
| 2010's | 157 (20.21) | 24.3611 |
| 2020's | 30 (3.86) | 2.80 |
| Authors | Studies |
|---|---|
| Corvol, P; Delorme, A; Guyene, PT; Menard, J | 1 |
| Alderman, M; Laragh, JH; Moon, C; Sealey, JE | 1 |
| Dworschack, RT; Printz, JM; Printz, MP | 1 |
| Dorer, FE; Kahn, JR; Lentz, KE; Levine, M; Skeggs, LT | 2 |
| Brown, JJ; Grant, J; Leckie, BJ; McConnell, A; Morton, JJ; Tree, M | 1 |
| Juliano, L; Oliveira, MC; Paiva, AC | 1 |
| Arakawa, K; Geji, T; Ikeda, M; Sakai, T; Yuki, M | 1 |
| Phillips, MI | 1 |
| Bangham, DR; Robertson, I; Robertson, JI; Robinson, CJ; Tree, M | 1 |
| Chesley, LC | 1 |
| Wernze, H | 1 |
| Johnston, CI; Morris, BJ | 1 |
| Giese, J | 1 |
| Symonds, EM | 2 |
| Peach, MJ | 1 |
| Boucher, R; Demassieux, S; Garcia, R; Genest, J; Gutkowska, Y | 1 |
| Aten, RF; Eisenfeld, AJ; Krakoff, LR | 1 |
| Reid, IA | 5 |
| Holzwarth, GJ; Lucas, CP; Pallas, KG; Stern, MP | 1 |
| Ganong, WF; Morris, BJ; Reid, IA | 1 |
| Ramsay, DJ | 1 |
| Felix, D; Ganten, D; Hoffman, WE; Phillips, MI; Weyhenmeyer, J | 1 |
| Lapshina, LA; Vlasenko, MA | 1 |
| Laragh, JH; Sealey, JE | 1 |
| Campbell, DJ; Dunn, JR; Fidge, NH; Mazzetti, J; Skinner, SL | 1 |
| Ganten, D; Hackenthal, E; Vecsei, P | 1 |
| Weiss, H; Wernze, H | 1 |
| Ganten, D; Schölkens, B; Steinbach, R | 1 |
| Hermann, JS; Russell, RP; Saito, H; Walker, WG; Whelton, PK | 1 |
| Christlieb, AR; Long, R | 1 |
| Brown, C; Ramsay, DJ; Reid, IA | 1 |
| Cier, JF | 1 |
| el-Zayyat, MF; Khayyal, MA | 1 |
| Funyu, T; Kawamata, A; Nigawara, K; Ono, K; Yagihashi, Y | 1 |
| Bing, J; Poulsen, K | 1 |
| Beevers, DG; Brown, JJ; Davies, DL; Ferriss, JB; Fraser, R; Lever, AF; Mason, P; Neville, AM; Robertson, JI | 1 |
| Müller, G; Spech, HJ; Wernze, H | 1 |
| Fitzsimons, JT; Kucharczyk, J; Richards, G | 2 |
| Bullivant, M | 1 |
| Kipen, H; Ramsay, DJ; Reid, IA; Simpson, JB | 1 |
| Fahrer, A; Ganten, D; Rettig, R; Schelling, P; Simon, W; Speck, G | 1 |
| Dávalos, M; Frega, NS; Leaf, A; Saker, B | 1 |
| Moffat, B; Reid, IA | 1 |
| Anderson, GH; Dalakos, TG; Elias, AN; Schroeder, ET; Streeten, DH | 1 |
| Haber, E | 1 |
| Ganten, D; Ganten, U; Schelling, P; Vecsei, P | 1 |
| Barrett, JC; Eggena, P; Sambhi, MP; Thananopavarn, C; Tuck, M; Wiedeman, CE | 1 |
| Barrett, JD; Chu, CL; Eggena, P; Sambhi, MP | 1 |
| Blair, ML; Feigl, EO; Smith, OA | 1 |
| Hiwada, K; Kokubu, T; Nishimura, K; Tanaka, H | 1 |
| Hong, JS; Poisner, AM | 1 |
| Oelkers, W; Schöneshöfer, M | 1 |
| Falge, C; Warnze, H; Weigand, K | 1 |
| Druilhet, RE; Kirkendall, WM; Overturf, M | 1 |
| Katz, FH; Roper, EF | 1 |
| Wilton, A | 1 |
| Bartter, FC; Kelly, GD; Yun, JC | 1 |
| Damkjaer, M; Giese, J; Kappelgaard, AM; Nielsen, M; Schioler, V | 1 |
| L'age, M; Oelkers, W | 1 |
| Hiwada, K; Kokubu, T; Nishimura, K | 1 |
| Dumas, ML; Premeau, MR; Tewksbury, DA | 1 |
| Beaty, O; Buckalew, VM; Schmid, HE; Sloop, CH | 1 |
| Hiwada, K; Kokubu, T; Tanaka, H | 1 |
| Blümel, A; Hammerstein, J; Oelkers, W; Schöneshöfer, M; Schwartz, U | 1 |
| Grün, M; Liehr, H; Wernze, H | 1 |
| Edwards, KD | 1 |
| Hasegawa, H; Lewis, LA; Masson, GM; Shainoff, JR | 1 |
| Dodd, VN; Gordon, DB; Sachin, IN | 1 |
| Campillo, JE; Garcia Del Rio, C; Osorio, C; Quesada, T | 1 |
| Doig, A; Fraser, R; Morton, JJ; Parboosingh, J; Robertson, JI; Weir, RJ; Wilson, A | 1 |
| Cleary, RE; Kramer, NJ; Petersen, LP; Weinberger, MH; Young, PC | 1 |
| Ehrlich, EN; Lindheimer, MD; Low, J; Oparil, S | 1 |
| Holze, C; Molzahn, M; Oelkers, W; Soerensen, R | 1 |
| Bernardi, M; Müller, G; Spech, HJ; Wellhöfer, G; Wernze, H; Wilkinson, SP | 1 |
| Hackenthal, E; Hackenthal, R; Hofbauer, KG | 1 |
| Briggs, JD; Brown, JJ; Fraser, R; Gavras, H; Lever, AF; Medina, A; Morton, JJ; Oliver, NW; Paton, AM; Robertson, JI; Tree, M | 1 |
| Kotchen, JM; Kotchen, TA; Miller, MC; Talwalkar, RT; Welch, WJ | 1 |
| Goodfriend, TL; Peach, MJ | 1 |
| Fleming, BJ; Genuth, SM; Gould, AB; Kamionkowski, MD | 1 |
| Hasatani, K | 1 |
| Hiwada, K; Kokubu, T; Yamamura, Y | 1 |
| Ramsay, DJ; Reid, IA | 1 |
| Lee, HL; Pavanaram, SK; Sen, S; Smeby, RR; Turcotte, JG; Yu, CS | 1 |
| Campbell, DJ; Skinner, SL | 1 |
| Low, J; Oparil, S | 1 |
| Oelkers, W; Schultze, G | 1 |
| Gordon, DB; Sachin, IN | 1 |
| Beyer, JC; Gallenkamp, H; Wernze, H | 1 |
| Kolchanov, NA; Poliak, MG; Zhegalina, LV | 1 |
| Smith, IK | 1 |
| Bókay, P; Rácz, O; Sonkodi, S | 1 |
| Kentera, D; Sparks, JC; Susic, D | 1 |
| Breuer, H; Kaulhausen, H | 1 |
| Baker, PN; Broughton Pipkin, F; Symonds, EM | 2 |
| Brosnihan, KB; Ferrario, CM; Kohara, K; Milsted, A | 1 |
| Leite, R; Salgado, MC | 1 |
| Beraldo, WT; Gualberto, MP; Nunes, RL; Pesquero, JL | 1 |
| Okamura, T; Toda, N; Wang, Y | 1 |
| Andries, M; Denef, C; Robberecht, W | 1 |
| Carey, RM; Geary, KM; Gomez, RA; Hunt, MK; Norling, LL; Peach, MJ; Ramos, SP | 1 |
| Bouyounes, B; Dzau, VJ; Ingelfinger, JR; Jackson, B; Jacob, H; Schunkert, H | 1 |
| Bader, M; Ganten, D; Ganten, U; Hilgenfeldt, U; Michel, JB; Paul, M; Ruf, P; Wagner, J; Zeh, K; Zimmermann, F | 1 |
| Avery, B; Dantzer, V; Hagemann, A; Nielsen, AH; Poulsen, K | 1 |
| Dessì-Fulgheri, P; Fallo, F; Lanari, A; Mantero, F; Paci, VM; Pistorello, M; Rappelli, A; Sarzani, R | 1 |
| Campbell, DJ; Clark, IJ; Lawrence, AC | 1 |
| Araujo, GW; Lindsey, CJ; Paiva, AC; Pesquero, JB; Pesquero, JL | 1 |
| Brosnihan, KB; Chappell, MC; Diz, DI; Ferrario, CM; Millsted, A | 1 |
| Higaki, J; Miyazaki, M; Morishita, R; Ogihara, T | 1 |
| Major, TC; Panek, RL; Rapundalo, ST; Simmerman, J; Taylor, DG; Weishaar, RE | 1 |
| Samani, NJ; Swales, JD | 1 |
| Ganten, D; Hilgenfeldt, U; Hilgers, KF; Kuczera, M; Lisson, C; Mann, JF; Ritz, E | 1 |
| Story, DF; Ziogas, J | 2 |
| Campbell, DJ; Kladis, A; Skinner, SL; Whitworth, JA | 1 |
| Beldent, V; Kettani, S; Ronco, P; Rousselet, MC; Saint-Andre, JP; Verroust, P | 1 |
| Aalkjaer, C; Kvist, S; Mulvany, MJ | 1 |
| Dzau, VJ; Gibbons, GH; Pratt, RE | 1 |
| Brosnihan, KB; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Milsted, A; Tallant, EA | 1 |
| Gesellchen, PD; Steinberg, MI; Wiest, SA; Zimmerman, K | 1 |
| Abe, Y; Iwao, H | 1 |
| Deschepper, CF; Ganong, WF | 1 |
| Gierschik, P; Hackenthal, E; Klett, C; Muller, F | 1 |
| Ganten, D; Hellmann, T; Keuneke, C; Metzger, R; Peters, J; Yacullo, R | 1 |
| Deschepper, CF; Reudelhuber, TL | 1 |
| Coezy, ED; Corvol, P; Howlett, AC | 1 |
| Campbell, DJ; Kladis, A; Ziogas, J | 1 |
| Abe, Y; Fukui, K; Iwao, H; Kimura, S; Nakamura, A; Tamaki, T | 2 |
| Basso, N; Kurnjek, ML; Mikulic, L; Trolliet, MR | 1 |
| Yoshimi, H | 1 |
| Cressier, F; Eglème, C; Wood, JM | 1 |
| Ganten, D; Jin, MW; Lindpaintner, K; Niedermaier, N; Wilhelm, MJ | 1 |
| Sernia, C; Thomas, WG | 1 |
| Fukuchi, S; Higashimori, K; Inagami, T; Mizuno, K; Shimamoto, K; Stone, WJ | 1 |
| Müller-Schweinitzer, E; Olea-Baza, I | 1 |
| Dzau, VJ; Ellison, KE; Fon, EA; Ingelfinger, JR; Zuo, WM | 1 |
| Abe, Y; Fukui, K; Iwao, H; Kimura, S; Nakamura, A; Nakanishi, S; Tamaki, T | 1 |
| Atrash, B; Donovan, B; Hallett, A; Jones, DM; Leckie, B; Lever, AF; Morton, JJ; Sueiras-Diaz, J; Szelke, M; Tree, M | 1 |
| Aalkjaer, C; Juul, B; Mulvany, MJ | 1 |
| Corvol, P; Guettier, C; Ménard, J; Michel, JB; Reade, R; Sayah, S | 1 |
| Corvol, P; Gardes, J; Gonzalez, MF; Menard, J; Misumi, J | 1 |
| Dzau, VJ; Ingelfinger, JR | 1 |
| Dzau, VJ | 3 |
| Cantau, B; Chapnick, B; Coezy, E; Corvol, P; Darby, I; Donnadieu, MH; Escher, E; Mizrahi, J; Nussberger, J | 1 |
| Leckie, BJ; Lever, AJ; Manhem, PJ; Morton, JJ; Robertson, JI; Semple, PF; Szelke, M; Webb, DJ | 1 |
| Mitchell, KD; Navar, LG | 1 |
| Ashworth, C; Cressier, F; Eglème, C; Hofbauer, KG; Wood, JM | 1 |
| Bumpus, FM; Husain, A; Moffett, RB | 1 |
| Badoer, E; Ganten, D; Lang, RE; Rettig, R; Unger, T | 1 |
| Ganten, D; Lang, RE; Unger, T | 1 |
| Abe, Y; Fukui, K; Iwao, H; Kim, S; Nakanishi, S; Nakayama, K; Ohkubo, H | 1 |
| Forslund, T; Fyhrquist, F; Linkola, J; Nieminen, MM; Tikkanen, I | 1 |
| Fitzsimons, JT; Fuller, LM | 1 |
| Ganten, D; Hackenthal, E; Hellmann, W; Klett, C; Nakanishi, S; Ohkubo, H; Suzuki, F | 1 |
| Ganten, D; Hackenthal, E; Hellmann, W; Klett, C; Müller, F; Nakanishi, S; Ohkubo, H; Suzuki, F | 1 |
| Cantau, B; Coezy, ED; Corvol, P; Darby, IA; Donnadieu, MH; Mizrahi, J; Nussberger, J | 1 |
| Better, OS; Finberg, JP; Kahana, L; Naveh, Y | 1 |
| Masenko, VP; Uchitel', IA; Ustinova, SE | 1 |
| Higashimori, K; Imada, T; Inagami, T; Mizuno, K | 1 |
| Hermann, K; Hilgenfeldt, U; Phillips, MI; Raizada, MK | 1 |
| Hackenthal, E; Klett, C | 2 |
| Handa, M; Igarashi, Y; Kondo, K; Saruta, T; Senba, S; Suzuki, H | 1 |
| Ferrario, CM; Saruta, T; Suzuki, H | 1 |
| Celio, MR; Felix, D; Harding, JW; Hilgenfeldt, U; Imboden, H | 1 |
| Diego, AM; Jiménez, E; Montiel, M; Morell, M; Narváez, JA; Ruiz, M | 1 |
| Kitamura, N | 1 |
| Hackenthal, E; Klett, C; Komischke, K; Radziwill, R; Stuzmann, M | 1 |
| Falge, C; Weigand, K; Wernze, H | 1 |
| Cushman, DW; Ondetti, MA | 1 |
| Saruta, T | 1 |
| Burton, J; Cody, RJ; Haber, E; Herd, JA | 1 |
| Evered, MD; Fitzsimons, JT | 1 |
| Hackenthal, E; Hilgenfeldt, U; Rix, E; Taugner, R | 1 |
| Dimitrov, T | 1 |
| Cody, RJ | 1 |
| Bührle, CP; Hackenthal, E; Mannek, E; Nobiling, R; Schneider, D; Taugner, R | 1 |
| Deboben, A; Ganten, D; Lang, RE; Paul, M; Unger, T | 1 |
| Hofbauer, KG; Wood, JM | 1 |
| Ganten, D; Schelling, P; Speck, G; Unger, T | 1 |
| Boucher, R; Genest, J; Grisé, C; Thibault, G | 1 |
| Genest, J; Thibault, G | 1 |
| Boucher, R; Garcia, R; Genest, J; Gutkowska, J; Schiffrin, EL | 1 |
| Klickstein, LB; Wintroub, BU | 1 |
| Hackenthal, E; Nobiling, R; Poulsen, K; Rix, E; Taugner, R | 1 |
| Sokabe, H | 1 |
| Hirose, S; Imai, N; Murakami, K | 1 |
| Mowchanuk, MD; Sernia, C | 1 |
| Felix, D; Schelling, P | 1 |
| Wiecek, A | 1 |
| Hasegawa, M; Horiuchi, T; Kinouchi, T; Shimizu, N; Yoshida, H | 1 |
| Carr, BR; Gant, NF | 1 |
| Damkjaer Nielsen, M; Giese, J; Ibsen, H; Leth, A; Rasmussen, S | 1 |
| Gaida, W; Ganten, D; Kraft, K; Lang, RR; Unger, T | 1 |
| Forslund, T; Fyhrquist, F; Grönhagen-Riska, C; Hortling, L; Immonen, I; Tikkanen, I | 1 |
| Oliver, JA; Sciacca, RR | 1 |
| Atrash, B; Donovan, B; Gamble, J; Hallett, A; Hughes, M; Jones, DM; Leckie, B; Lever, AF; Morton, JJ; Tree, M | 1 |
| Alhenc-Gelas, F; Bouhnik, J; Corvol, P; Ménard, J; Misumi, J | 1 |
| Bayer, C; Ganten, D; Hermann, K; Lang, RE; Unger, T | 1 |
| Herrmann, HC; Morris, BJ; Reid, IA | 1 |
| de Jong, W; Tonnaer, JA; Verhoef, J; Wiegant, VM | 1 |
| Ganten, D; Ganten, U; Schelling, P; Sponer, G; Unger, T | 1 |
| Reid, IA; Sernia, C | 1 |
| Macrae, WA; Morton, JJ; Semple, PF | 1 |
| Braley, LM; Menachery, A; Williams, GH | 1 |
| Broughton Pipkin, F; Jadoul, FA; Lamming, GD | 1 |
| Faulhaber, HD; Hamann, B; Hamann, KM | 1 |
| Hiwada, K; Kokubu, T; Murakami, E | 1 |
| Printz, MP; Wallis, CJ | 1 |
| Molzahn, M; Piefke, S; Schultze, G | 1 |
| Davalos, M; Frega, NS; Leaf, A | 1 |
| Lee, YA; Lindpaintner, K; Raman, VK | 1 |
| el-Dahr, SS; Navar, LG; Vari, RC; Von Thun, AM | 1 |
| Aoki, M; Fukamizu, A; Higaki, J; Kaneda, Y; Mikami, H; Morishita, R; Murakami, K; Nakamura, Y; Ogihara, T; Tomita, N | 1 |
| Peters, J | 1 |
| Arakawa, K; Ideishi, M; Ikeda, M; Miura, S; Ogata, S; Sasaguri, M | 1 |
| Bader, M; Ganten, D; Hackenthal, E; Klett, C; Schwemmle, M | 1 |
| Ganten, D; Hübner, N; Kreutz, R; Lindpaintner, K; Takahashi, S | 1 |
| Bouhnik, J; Corvol, P; Gonzalez, MF; Huang, H; Ménard, J; Skinner, S | 1 |
| Broughton Pipkin, F; Lal, S; Sharif, J | 1 |
| Browe, CS; Ross, EA; Rutledge, DR | 1 |
| Büch, M; Gerstberger, R; Paul, M; Rettig, R; Schnatterbeck, P | 1 |
| Deschepper, CF | 1 |
| Brosnihan, B; Bunnemann, B; Cintra, A; Ganten, D; Hasselrot, U; Hilgenfeldt, U; Lippoldt, A; Metzger, R; Rosén, L; Ueki, A | 1 |
| Geiger, H; Hilgers, KF; Mai, M; Mann, JF; Wagner, J | 1 |
| Bhandaru, S; Claycomb, WC; Cook, JL; Giardina, JF; Ré, RN | 1 |
| Camargo, MJ; Gahnem, F; Laragh, JH; Sealey, JE; von Lutterotti, N | 2 |
| Kawaguchi, H; Kitabatake, A | 1 |
| Cockcroft, JR; O'Kane, KP; Webb, DJ | 1 |
| Carrière, S; Chan, JS; Delalandre, A; Lachance, S; Ming, M; Wu, J | 1 |
| Cumin, F; Kelly, M; Samani, NJ; Wood, JM | 1 |
| Doris, PA | 1 |
| Aldred, K; Hardy, KJ; Phillips, PA; Rolls, KA | 1 |
| Campbell, DJ; Duncan, AM; Kladis, A | 2 |
| Holmer, SR; Riegger, G; Schunkert, H | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Lamers, JM; Saxena, PR; Schalekamp, MA; Verdouw, PD | 1 |
| Admiraal, PJ; Danser, AH; de Bruyn, JH; Derkx, FH; Schalekamp, MA | 1 |
| Bunnemann, B; Fuxe, K; Ganten, D | 1 |
| Hilgenfeldt, U; Schwind, S | 1 |
| Gierschik, P; Hackenthal, E; Klett, C; Nobiling, R | 1 |
| Izumo, S; Sadoshima, J; Slayter, HS; Xu, Y | 1 |
| Gomez, RA; Tufro-McReddie, A | 1 |
| Bader, M; Ganten, D; Hackenthal, E; Klett, C | 1 |
| Marumo, F; Nonoguchi, H; Terada, Y; Tomita, K | 1 |
| Diamant, D; Dzau, VJ; Ingelfinger, JR; Litwin, SE; Riegger, G; Schunkert, H; Tang, SS | 1 |
| Izumo, S; Sadoshima, J | 1 |
| Chai, CY; Ganten, D; Hellmann, W; Luft, FC; Tseng, CJ | 1 |
| Hou, X; Vicaut, E | 1 |
| Barrett, JD; Clegg, K; Eggena, P; Zhu, JH | 1 |
| Higaki, J; Ishii, K; Mikami, H; Miyazaki, M; Morishita, R; Nagano, M; Nakamura, F; Ogihara, T; Okunishi, H | 1 |
| Inagami, T; Inui, H; Iwai, N; Kato, H; Kimoto, K; Uchiyama, Y | 1 |
| Fukamizu, A; Hatae, T; Kajiwara, N; Murakami, K; Seo, MS; Sugimura, K; Sugiyama, F; Takahashi, S; Takimoto, E; Yagami, K | 2 |
| Ganten, D; Hilgenfeldt, U; Hilgers, KF; Luft, FC; Mann, JF; Muley, T; Veelken, R | 1 |
| el-Dahr, SS; Yosipiv, IV | 1 |
| Campbell, DJ; Duncan, AM; Harrap, SB; Kladis, A | 1 |
| Phillips, MI; Simon, A; Toffolo, S; Wielbo, D | 1 |
| Fogo, A; Ichiki, T; Inagami, T; Kakuchi, J; Labosky, PA; Naftilan, AJ; Niimura, F; Oikawa, T; Okubo, S; Yoshida, H | 1 |
| Riordan, JF | 1 |
| Dluhy, RG; Hallouin, MC; Hollenberg, NK; Hopkins, PN; Jeunemaitre, X; Lalouel, JM; Lifton, RP; Skuppin, J; Williams, CS; Williams, GH; Williams, RR | 1 |
| Laurent, V; Salzet, M | 1 |
| Corvol, P; Giacchetti, G; Griffin, CA; Llorens-Cortes, C; Schambelan, M; Sechi, LA; Valentin, JP | 1 |
| Jardine, I; Schwartz, JC | 1 |
| Sun, Y; Weber, KT | 1 |
| Brasier, AR; Li, J | 1 |
| Hymel, A; Imig, JD; Navar, LG; Ono, H; von Thun, AM; Zou, LX | 1 |
| Perryman, MB; Raynolds, MV | 1 |
| Cumin, F; Davidson, EA; De Gasparo, M; Elena, PP; Luttenauer, L; Mathis, GA; Ramirez, M | 1 |
| Fukamizu, A; Horiguchi, H; Ishida, J; Murakami, K; Sugiyama, F; Takimoto, E | 1 |
| Aoki, M; Higaki, J; Kaneda, Y; Morishita, R; Ogihara, T; Tomita, N; Tomita, S | 1 |
| Campbell, SE; Cicila, GT; Katwa, LC; Lee, SJ; Tyagi, SC; Weber, KT | 2 |
| Potter, WD; Slembrouck, D; Wang, JM | 1 |
| Gura, T | 1 |
| Hollenberg, NK; Hopkins, PM; Jeunemaitre, X; Williams, GH | 1 |
| Fogo, A; Ichikawa, I; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Takemoto, F | 1 |
| Hermann, K; Ring, J | 2 |
| Gallagher, AM; Klett, CP; Palmer, A; Printz, MP; Rioseco-Camacho, N | 1 |
| Bellini, C; Ferri, C; Fisher, ND; Gleason, R; Hollenberg, NK; Santucci, A; Seely, EW; Williams, GH | 1 |
| Bader, M; Eggena, P; Ganten, D; Klett, CP; Printz, MP | 1 |
| Cassis, L; Shenoy, U | 1 |
| Angius, A; Balata, F; Cao, A; Cherchi, A; Cherchi, PA; Olla, N; Onnis, E; Pirastu, M; Poddie, D; Sole, G; Zedda, N | 1 |
| Fukamizu, A; Hibi, K; Ishigami, T; Ishii, M; Kihara, M; Mizuno, K; Murakami, K; Nyui, N; Ochiai, H; Ohno, S; Tamura, K; Umemura, S; Yabana, M | 1 |
| Anversa, P; Capogrossi, MC; Cheng, W; Cirielli, C; Kajstura, J; Nitahara, JA; Pierzchalski, P; Reiss, K; Rizk, M | 1 |
| Chen, YF; Krege, JH; Meng, QC; Oparil, S; Smithies, O; Tian, B | 1 |
| Broughton Pipkin, F; Forhead, AJ; Fowden, AL; Sutherland, MF | 1 |
| Brown, L; Marchant, C; Sernia, C; Wall, D | 1 |
| Fukamizu, A | 2 |
| Fukamizu, A; Goto, K; Hama, H; Kakinuma, Y; Murakami, K; Sugiyama, F | 1 |
| Beattie, C; Beattie, SR; Jones, DM; Leckie, BJ; Morton, JJ; Sueiras-Diaz, J; Szelke, M | 1 |
| Ailhaud, G; Aubert, J; Darimont, C; Negrel, R; Safonova, I | 1 |
| Fukamizu, A; Ishigami, T; Ishii, M; Kihara, M; Kobayashi, S; Miyazaki, H; Murakami, K; Nyui, N; Ochiai, H; Sumida, Y; Tamura, K; Umemura, S; Yabana, M | 1 |
| Burns, KD; Kontogiannis, J | 1 |
| Chen, X; Fogo, A; Ichikawa, I; Inagami, T; Matsusaka, T; Niimura, F; Nishimura, H; Okubo, S; Tsuchida, S; Utsunomiya, H | 1 |
| Fukamizu, A; Ishii, M; Kihara, M; Murakami, K; Nyui, N; Sumida, Y; Tamura, K; Umemura, S; Yabana, M; Yokoyama, N | 1 |
| Fogo, A; Hogan, BL; Ichikawa, I; Matsusaka, T; Niimura, F; Okubo, S | 1 |
| Diamond, JA; Gharavi, A; Phillips, RA | 1 |
| Iizuka, K; Kawaguchi, H; Kitabatake, A; Murakami, T; Okamoto, H; Sano, H | 1 |
| Dhar, M; Mascareno, E; Siddiqui, MA | 1 |
| Fregly, MJ; Kimura, B; Peng, JF; Phillips, MI | 1 |
| Aubert, JF; Brunner, DB; Brunner, HR; Gabbiani, G; Mazzolai, L; Nussberger, J; Pedrazzini, T | 1 |
| Berg, K; Berge, KE | 1 |
| Danser, AH; Sassen, LM; Schalekamp, MA; van Kats, JP; van Meegen, JR; Verdouw, PD | 1 |
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| Campbell, SE; Dhalla, AK; Kandala, JC; Katwa, LC; Sun, Y; Tyagi, SC; Weber, KT | 1 |
| Fukamizu, A; Goto, K; Hama, H; Kakinuma, Y; Murakami, K; Sugiyama, F; Yagami, K | 1 |
| Barrett, JD; Eggena, P; Hori, MT; Kamide, K; Tuck, ML; Zhu, JH | 1 |
| Chang, J; Hilepo, J; Hirsch, L; Mento, PF; Pica, ME; Wilkes, BM | 1 |
| Daemen, MJ; de Leeuw, PW; Geraedts, JP; Kroon, AA; Spiering, W; Vreugdenhil, HA | 1 |
| Anastasopoulos, F; Briscoe, TA; Campbell, DJ; Duncan, AM; James, GM; Kladis, A | 1 |
| Brechler, V; Deschepper, CF; Gallo-Payet, N; Laflamme, L; Reudelhuber, TL | 1 |
| Carlsson, B; Carlsson, LM; Karlsson, C; Lindell, K; Ottosson, M; Sjöström, L | 1 |
| Luft, FC; Müller, DN | 1 |
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| Fukamizu, A; Ishikawa, K; Kai, T; Kurooka, A; Murakami, K; Shimada, S; Sugimura, K; Takenaka, T | 1 |
| Cervenka, L; Harrison-Bernard, LM; Mitchell, KD; Navar, LG; Wang, CT | 1 |
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| Berger, S; Corvol, P; Gasc, JM; Hubert, C; Schütz, G | 1 |
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| Ishikawa, K; Kai, T; Kurooka, A; Shimada, S; Sugimura, K | 1 |
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| Briscoe, TA; Campbell, DJ; Kladis, A; Zhuo, J | 1 |
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| Danser, AH; Dekkers, DH; Lamers, JM; Saris, JJ; Saxena, PR; Schalekamp, MA; van Kesteren, CA | 1 |
| Higaki, J; Ishikawa, K; Katsuya, T; Ogihara, T; Sato, N | 1 |
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| Ang, E; Ibarra-Sunga, O; Uhal, BD; Wang, R; Zagariya, A | 1 |
| Fukamizu, A; Horiguchi, H; Kakinuma, Y; Murakami, K; Ogata, T; Sugiyama, F; Taniguchi, K; Yagami, K | 1 |
| Boldogh, I; Brasier, AR; Han, Y; Jamaluddin, M; Meng, T; Sun, J | 1 |
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| Bader, M; Baltatu, O; Ganten, D; Silva, JA | 1 |
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| Bader, M; Breu, V; Ganten, D; Gross, V; Haller, H; Luft, FC; Mervaala, E; Müller, DN; Park, JK; Schmidt, F | 1 |
| Hata, T; Makino, N; Ohtsuka, S; Sawada, S; Sugano, M | 1 |
| Danser, AH; Saris, JJ; Schuijt, MP; van Kats, JP | 1 |
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| Border, WA; Noble, NA | 1 |
| Crisman, JM; Diamond, JR; Franzoni, DF; Ricardo, SD; Roesener, CD | 1 |
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| Amer, S; Aves, SJ; Brown, JA; Paley, RK | 1 |
| Makino, N; Sawada, S; Sugano, M; Tsuchida, K | 1 |
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| Anversa, P; Bishopric, NH; Fiordaliso, F; Kajstura, J; Leri, A; Limana, F; Setoguchi, M; Webster, K | 1 |
| Lake-Bruse, KD; Sigmund, CD | 1 |
| Guo, DF; Inagami, T; Kimura, H; Naito, A; Nakamura, T; Obata, J; Shimizu, F; Takano, H; Yoshida, Y | 1 |
| Aubert, JF; Brunner, HR; Pedrazzini, T; Pellieux, C; Sauthier, T | 1 |
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| Fung, ML; Leung, PS; Sernia, C | 1 |
| Burns, KD; Imig, JD; Kumar, D; Levine, DZ; Navar, LG; Wehbi, G; Zimpelmann, J | 1 |
| Bader, M; Böhm, M; Bricca, G; Ganten, D; Monti, J; Schinke, M | 1 |
| Ailhaud, G; Fukamizu, A; Massiera, F; Negrel, R; Saint-Marc, P; Teboul, M | 1 |
| Furukawa, T; Katsuragi, T; Kushiku, K; Shibata, K; Tokunaga, R; Yamada, H | 1 |
| Cattran, DC; Duncan, JA; Floras, JS; Kang, AK; Lai, V; Miller, JA; Scholey, JW | 1 |
| Belova, LA | 1 |
| Katsuya, T; Ogihara, T | 1 |
| Harrison-Bernard, LM; Kobori, H; Navar, LG | 2 |
| Lalouel, JM; Morgan, T; Rohrwasser, A; Terreros, D; Ward, K | 1 |
| Baker, KM; Booz, GW; Dostal, DE | 1 |
| Bader, M; Baltatu, O; Caligiorni, S; Campagnole-Santos, MJ; Fontes, MA; Ganten, D; Santos, RA | 1 |
| Hopkins, PN; Hunt, SC; Hurwitz, S; Jeunemaitre, X; Litchfield, WR; Potter, B; Weiss, RJ; Williams, GH | 1 |
| Galli, SM; Kagiyama, S; Phillips, MI; Varela, A | 1 |
| Keen, HL; Sigmund, CD | 1 |
| Bader, M; Baltatu, O; Bricca, G; Ganten, D; Janssen, BJ; Monti, J; Plehm, R | 1 |
| Cheng, ZJ; Fiebeler, A; Ganten, D; Ganten, U; Lapatto, R; Luft, FC; Mervaala, EM; Müller, DN; Nurminen, K; Tikkanen, I; Vapaatalo, H | 1 |
| Ganten, D; Huang, BS; Leenen, FH | 1 |
| Campbell, DJ; Dodic, M; Peers, A; Wintour, EM | 1 |
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| Löffler, G; Schling, P | 1 |
| Bader, M; Grecksch, G; Hoehe, MR; Maul, B; Siems, WE; Walther, T | 1 |
| Bieringer, M; Dechend, R; Dietz, R; Fiebeler, A; Gulba, D; Haller, H; Luft, FC; Mervaala, E; Muller, DN; Park, JK; Theuer, J | 1 |
| Inagaki, K; Iwanaga, Y; Kataoka, K; Kihara, Y; Onozawa, Y; Sasayama, S; Yoneda, T | 1 |
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| Sim, MK; Tang, FR; Tham, M | 1 |
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| Fisher, ND; Hollenberg, NK; Hurwitz, S; Jeunemaitre, X; Price, DA; Williams, GH | 1 |
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| Patston, PA; Ramaha, A | 1 |
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| Harrison-Bernard, LM; Kobori, H; Navar, LG; Nishiyama, A | 2 |
| Nakamura, A; Niimi, R; Yanagawa, Y | 1 |
| Fisher, ND; Hollenberg, NK; Hopkins, PN; Hunt, SC; Jeunemaitre, X; Smith, B; Solorio, D; Williams, GH | 1 |
| Bader, M; Baltatu, O; Campagnole-Santos, MJ; Couto, AS; Ganten, D; Santos, RA | 1 |
| Engeli, S; Gorzelniak, K; Janke, J; Luft, FC; Sharma, AM | 1 |
| Murakami, K | 1 |
| Ailhaud, G; Massiera, F; Teboul, M | 1 |
| Honeck, H; Kaergel, E; Luft, FC; Mullally, A; Muller, DN; Schunck, WH; Shagdarsuren, E; Theuer, J | 1 |
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| Danser, AH; de Bruin, RJ; de Wit, E; Deinum, J; Reudelhuber, TL; Sluiter, W; van den Eijnden, MM | 1 |
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| Arckens, L; Courtoy, PJ; De Potter, WP; Leenen, FH; Slembrouck, D; Tan, J; Wang, JM | 1 |
| Dodic, M; Douglas-Denton, R; Johnson, K; Moritz, KM; Wintour, EM | 1 |
| Lochard, N; Mercure, C; Reudelhuber, TL; Silversides, DW; van Kats, JP | 1 |
| Dechend, R; Fiebeler, A; Finckenberg, P; Haller, H; Hampich, F; Heidecke, H; Ju, X; Kreuzer, J; Luft, FC; Mervaala, E; Muller, DN; Park, JK; Shagdarsuren, E; Theuer, J; Viedt, C; Zenke, M | 1 |
| Amedeo Modesti, P; Bertolozzi, I; Boddi, M; Cecioni, I; Coppo, M; Formigli, L; Perna, AM; Polidori, G; Serneri, GG; Vanni, S; Zecchi-Orlandini, S | 1 |
| Kimura, B; Peng, J; Phillips, MI | 1 |
| Aebi, JD; Blum-Kaelin, D; Dechend, R; Dehmlow, H; Fiebeler, A; Haller, H; Löffler, BM; Luft, FC; Masur, S; Mullally, A; Muller, DN; Park, JK; Pilz, B | 1 |
| deChâtel, R; Ilves, M; Kinnunen, P; Piuhola, J; Ruskoaho, H; Szokodi, I; Vuolteenaho, O | 1 |
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| Ailhaud, G; Boschmann, M; Engeli, S; Gorzelniak, K; Janke, J; Massiéra, F; Schling, P; Sharma, AM; Teboul, M | 1 |
| Albertazzi, A; Anglani, F; Bernich, P; Brezzi, B; D'Angelo, A; Del Prete, D; Furci, L; Gambaro, G; Graziotto, R; Lupo, A; Magistroni, R; Maschio, G; Modena, F | 1 |
| Al-Garawi, A; Arroyo, V; Bataller, R; Colmenero, J; Ginès, P; Gutiérrez-Ramos, JC; Jiménez, W; Lora, JM; Nicolás, JM; Rodés, J; Sancho-Bru, P; Solé, M; Weich, N | 1 |
| Bond, R; Brinsa, TA; Dell'Italia, L; Diwan, A; Evans, K; Flesch, M; Höper, A; Mann, DL; Peshock, R; Sivasubramanian, N; Spinale, FG; Wei, CC | 1 |
| Corvol, P; Ferri, C; Hollenberg, NK; Hopkins, PN; Hunt, SC; Jeunemaitre, X; Kosachunhanun, N; Mortensen, RM; Williams, GH; Williams, RR | 1 |
| Menrad, A; Orzechowski, HD; Paul, M; Schirner, M; Siemeister, G; Walther, T | 1 |
| Delbridge, LM; Domenighetti, AA; Huggins, CE; Pedrazzini, T; Pepe, S | 1 |
| Ip, SP; Leung, PS; Tsai, SJ; Wong, TP | 1 |
| Abboud, FM; Chapleau, MW; Davisson, RL; Hingtgen, SD; Ma, X; Sigmund, CD; Tian, X | 1 |
| Carlsson, PO; Lau, T; Leung, PS | 1 |
| Fukasawa, C; Hara, M; Harigai, M; Kamatani, N; Kawaguchi, Y; Nishimagi, E; Sugiura, T; Takagi, K | 1 |
| Crescenzi, A; Michelini, LC; Sangaleti, CT | 1 |
| Barbosa-Sicard, E; Dechend, R; Fiebeler, A; Haller, H; Honeck, H; Kaergel, E; Kirsch, T; Luft, FC; Markovic, M; Muller, DN; Park, JK; Rothe, M; Schunck, WH; Shagdarsuren, E; Theuer, J; Wellner, M | 1 |
| Ebihara, A; Hirata, Y; Iimuro, S; Iwata, H; Kangawa, K; Nagai, R; Niu, P; Shindo, T; Suematsu, Y; Takeda, N; Zhang, Y | 1 |
| Li, X; Rayford, H; Shu, R; Uhal, BD; Zhuang, J | 1 |
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| Cassell, MD; Gross, KW; Lavoie, JL; Sigmund, CD | 1 |
| Kobori, H; Navar, LG; Ozawa, Y; Prieto-Carrasquero, MC | 1 |
| Ganten, D; Huang, BS; Leenen, FH; Wang, H | 1 |
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| Barinas-Mitchell, E; Cottam, DR; Eid, G; Kelley, DE; Kuller, L; Mattar, SG; Schauer, PR | 1 |
| Cassis, L; Inagami, T; Loghman-Adham, M; Soto, CE | 1 |
| Heringer-Walther, S; Hohmann, C; Schultheiss, HP; Schulze, K; Steendijk, P; Tschöpe, C; Walther, T; Westermann, D | 1 |
| Ann Tallant, E; Ferrario, CM; Gallagher, PE; Richmond, RS; Strawn, WB | 1 |
| Ichihara, A; Kobori, H; Navar, LG; Nishiyama, A | 1 |
| Bounoua, F; Corry, DB; Eggena, P; Eslami, P; Nyby, MD; Tuck, ML | 1 |
| Barker, S; O'Mahony, OA; Puddefoot, JR; Vinson, GP | 1 |
| Pitt, B | 1 |
| Cassell, MD; Chapleau, MW; Morimoto, S; Sakai, K; Sigmund, CD | 1 |
| Hayashi, M; Ichihara, A; Inagami, T; Ishida, Y; Kaneshiro, Y; Koura, Y; Nabi, AH; Nakagawa, T; Nishiyama, A; Okada, H; Saruta, T; Suzuki, F; Tada, Y; Uddin, MN | 1 |
| Diz, DI; Ferrario, CM; Ganten, D; Kasper, SO | 1 |
| Chan, JS; Fantus, IG; Filep, JG; Fustier, P; Hamet, P; Hsieh, TJ; Ingelfinger, JR; Tang, SS; Wei, CC; Zhang, SL | 1 |
| Cassis, LA; Daugherty, A; Inagami, T; Lu, H; Rateri, DL | 1 |
| Dechend, R; Fiebeler, A; Haller, H; Honeck, H; Kaergel, E; Luft, FC; Muller, DN; Park, JK; Schunck, WH; Shagdarsuren, E; Theuer, J | 1 |
| Greene, AS; Oliveira, EB; Salgado, MC; Santos, CF | 1 |
| Aksu, S; Bayramoglu, F; Beyazit, Y; Büyükasik, Y; Dundar, S; Goker, H; Haznedaroglu, IC; Kekilli, M; Misirlioglu, M; Mollamahmutoglu, L; Ozcebe, O; Sayinalp, N; Tuncer, S | 1 |
| Finckenberg, P; Lindgren, L; Louhelainen, M; Luft, FC; Merasto, S; Mervaala, EM; Müller, DN; Vapaatalo, H | 1 |
| Floras, JS; Harvey, PJ; Miller, JA; Morris, BL | 1 |
| Leehey, DJ; Singh, AK; Singh, R | 1 |
| Sarlos, S; Wilkinson-Berka, JL | 1 |
| Chen, HC; Chuang, LY; Guh, JY; Hung, WC; Lee, CI; Yang, YL | 1 |
| Curl, CI; Delbridge, LM; Domenighetti, AA; Huggins, CE; Morgan, TO; Pedrazzini, T; Porrello, ER | 1 |
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| Inagami, T; Loghman-Adham, M; Sotelo-Avila, C; Soto, CE | 1 |
| Kobori, H; Nishiyama, A; Ozawa, Y; Suzaki, Y | 1 |
| Al-Saadi, N; Dechend, R; Fiebeler, A; Hilfenhaus, G; Jeng, AY; Luft, FC; Maser-Gluth, C; Meiners, S; Muller, DN; Nussberger, J; Rong, S; Shagdarsuren, E; Webb, RL; Wellner, M | 1 |
| Bie, P; Kjolby, MJ; Kompanowska-Jezierska, E; Wamberg, S | 1 |
| Delbridge, LM; Domenighetti, AA; Egger, M; Pedrazzini, T; Richards, SM; Wang, Q | 1 |
| Amore, A; Coppo, R; Lombardo, F; Merlini, E; Papalia, T; Peruzzi, L; Restagno, G; Silvestro, L | 1 |
| Fujita, T; Hayashi, M; Hirahashi, J; Hishikawa, K; Imai, N; Marumo, T; Saruta, T; Shimizu, N; Takase, O; Takayanagi, A | 1 |
| De Godoy, MA; Rattan, S | 1 |
| Didion, SP; Faraci, FM; Lamping, KG; Modrick, ML; Ryan, MJ; Sigmund, CD | 1 |
| Cassell, MD; Davis, DR; Sherrod, M; Sigmund, CD; Zhou, X | 1 |
| Braesen, JH; Dechend, R; Fiebeler, A; Gratze, P; Henke, N; Luft, FC; Muller, DN; Park, JK; Shagdarsuren, E; Wellner, M | 1 |
| Alenina, N; Bader, M; Becker, M; Gembardt, F; Krause, W; Maul, B; Pankow, K; Siems, WE; Walther, T | 1 |
| Iemitsu, M; Jesmin, S; Maeda, S; Miyauchi, T | 1 |
| Becari, C; Moysés, MK; Oliveira, EB; Salgado, MC; Santos, CF; Sivieri, DO | 1 |
| Hashimoto, Y; Kon, Y; Konno, A; Tamura, J | 1 |
| Baker, KM; Dostal, DE; Kumar, R; Sanghi, S; Smith, M | 1 |
| Cooper, ME; Thomas, MC; Tikellis, C | 1 |
| Brown, LA; Campbell, DJ; Clempus, RE; Elms, SC; Guidot, DM; Hart, CM; Polikandriotis, JA; Rupnow, HL; Sutliff, RL | 1 |
| Amiel, SA; Huang, GC; Jones, PM; Karalliedde, J; Muller, DS; Persaud, SJ; Ramracheya, RD; Viberti, G; Whitehouse, BJ; Wu, Y | 1 |
| Bruneval, P; Carmona, AK; Ferrans, VJ; Ikeda, Y; Moss, J; Pacheco-Rodriguez, G; Riemenschneider, WK; Valencia, JC; Xavier, J; Yu, ZX | 1 |
| Almeida, WS; Campos, AH; Casarini, DE; Di Marco, GS; Maciel, TT; Schor, N | 1 |
| Agrawal, R; Bahlmann, FH; Bode-Böger, SM; Fliser, D; Haller, H; Kielstein, JT; Kirsch, T; Lindschau, C; Marx, A; Meier, M; Menne, J; Muller, D; Park, JK | 1 |
| Coelho, EF; Ferrari, MF; Fior-Chadi, DR; Maximino, JR | 1 |
| De Mello, WC | 2 |
| Barker, S; Puddefoot, JR; Tahmasebi, M; Vinson, GP | 1 |
| Dart, RA; Frome, WL; Kaiser, SJ; Luo, J; Pan, N; Tewksbury, DA | 1 |
| Kobori, H; Navar, LG; Ozawa, Y; Suzaki, Y | 1 |
| Davisson, RL; Lazartigues, E; Sakai, K; Sharma, RV; Sigmund, CD; Sinnayah, P | 1 |
| Danser, AH; Krop, M; van Esch, JH | 1 |
| Aranda, FJ; Aranda, P; Ferrario, CM; Gaitan, MJ; Mayor-Olea, A; Morcillo, L; Reyes-Engel, A; Ruiz, M | 1 |
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| Boustany-Kari, CM; Cassis, LA; Daugherty, A; Lu, H | 1 |
| Al-Saadi, N; Dechend, R; Feldt, S; Fiebeler, A; Fischer, R; Gapeljuk, A; Gratze, P; Haller, H; Luft, FC; Madwed, JB; Meiners, S; Muller, DN; Park, JK; Schirdewan, A; Shagdarsuren, E; Wellner, M | 1 |
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| Fan, F; Roman, RJ; Zhuo, JL | 1 |
| Gao, L; Li, J; Lv, J; Schmull, S; Wang, Z; Xue, S | 1 |
| Crespo-Garcia, S; Dechend, R; Dillinger, A; Fuchshofer, R; Haase, N; Herrspiegel, C; Joussen, AM; Kociok, N; Luft, FC; Müller, DN; Poglitsch, M; Reichhart, N; Skosyrski, S; Strauß, O | 1 |
| Clark, MA; Gowrisankar, YV | 1 |
| Ahmad, S; Cheng, CP; Collawn, JF; Dell Italia, LJ; Ferrario, CM; Groban, L; Varagic, J; Wang, H | 1 |
| Re, RN | 1 |
| Han, SH; Kang, HY; Kang, SW; Kim, S; Nam, BY; Oh, HJ; Paeng, J; Park, J; Park, JT; Ryu, DR; Um, JE; Yoo, TH | 1 |
| Li, XC; Zhuo, JL | 1 |
| Kagami, S; Urushihara, M | 1 |
| Ahmad, S; Collawn, JF; Dell'Italia, LJ; Ferrario, CM; Groban, L; Varagic, J; VonCannon, JL | 1 |
| Conner, CD; DuPlessis, M; Ketchem, CJ; Khundmiri, SJ; Lederer, ED; Merchant, M; Murray, RD; Wilkey, D | 1 |
| Cao, W; Cui, S; Jin, L; Wu, C; Wu, L; Yang, M; Zhou, Z | 1 |
| Kobori, H; Urushihara, M | 1 |
| Alenina, N; Bader, M; Danser, AHJ; Domenig, O; Essers, J; Garrelds, IM; Góes Martini, A; Leijten, FPJ; Paulis, L; Poglitsch, M; Qadri, F; Rajkovicova, R; Severs, D; Te Riet, L; Uijl, E; van der Pluijm, I; van Thiel, BS | 1 |
| Ahmad, S; Alhomida, AS; Ferrario, CM; Ola, MS | 1 |
| Agassandian, K; Agassandian, M; Cassell, MD; Grobe, JL; Liu, X; Sigmund, CD; Thompson, AP | 1 |
| Amato, A; Baldassano, S; Caldara, GF; Di Carlo, M; Mulè, F; Nuzzo, D; Picone, P; Rizzo, M | 1 |
| Nakagawa, P; Sigmund, CD | 1 |
| Hu, M; Liu, S; Song, L; Wang, H; Xing, C; Xu, X | 1 |
| Awan, FR; Hussain, M | 1 |
| Scherer, PE; Zhu, Q | 1 |
| Chen, Y; Hao, P; Liu, B; Wang, J; Wei, S; Xu, F; Xue, M; Yuan, Q; Zhang, R | 1 |
| Chen, JZ; Daugherty, A; Lu, HS; Mohammadmoradi, S; Sawada, H; Wu, CH | 1 |
| Hitomi, H; Kitabayashi, C; Kobara, H; Kobori, H; Konishi, Y; Li, L; Masaki, T; Morikawa, T; Nakano, D; Nishiyama, A; Zhang, Y | 1 |
| Li, XC; Zhang, J; Zheng, X; Zhu, D; Zhuo, JL | 1 |
| Ishigaki, S; Isobe, S; Kato, A; Matsuyama, T; Miyake, H; Ohashi, N; Otsuka, A; Suzuki, T; Tsuji, T; Yasuda, H | 1 |
| Awan, FR; Hussain, M; Khan, HN | 1 |
| Cohn, DM; Gatineau, E; Gong, M; Loria, AS; Poglitsch, M; Yiannikouris, F | 1 |
| Balakrishnan, A; Danser, AHJ; Daugherty, A; Graham, MJ; Howatt, DA; Lu, HS; Mullick, AE; Wang, J; Wang, Y; Wu, C; Wu, CH; Ye, F | 1 |
| Fu, H; Hou, FF; Li, A; Liu, Y; Tan, RJ; Xiao, L; Xu, B; Zhou, D; Zhou, L | 1 |
| Danser, AHJ; Lu, X; Sun, Y | 1 |
| Fleenor, BS; Loria, AS; Mahanes, TM; Murphy, MO; Ouyang, A; Yiannikouris, FB | 1 |
| Cassis, LA; Daugherty, A; Howatt, DA; Lu, HS; Moorleghen, JJ; Wu, C; Wu, CH | 1 |
| Ahmad, S; Cheng, CP; Ferrario, CM; Groban, L; Sun, X; VonCannon, JL; Wang, H; Wright, KN | 1 |
| Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Melton, L; Mirabito Colafella, KM; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Biasch, K; El Omar, R; Freund, JN; Gachet, C; Julien, E; Lanza, F; Tavian, M | 1 |
| Bovée, DM; Clahsen-van Groningen, MC; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Lu, X; Melton, L; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I | 1 |
| Ahmad, S; Ferrario, CM; Groban, L; Punzi, HA; Wright, KN | 1 |
| Batlle, D; Soler, MJ | 1 |
| Demura, M; Takeda, Y; Yoneda, T | 1 |
| Chen, S; Daugherty, A; Lin, Y; Lu, HS; Mullick, AE; Ning, L; Rong, J; Shi, P; Tao, X; Wang, J; Xu, Y; Zhang, Z; Zheng, H | 1 |
| Chang, J; Du, J; Ge, X; Li, X; Li, YC; Liu, W; Nie, H; Sun, Y; Wei, X; Xun, Z | 1 |
| Jones, SP | 1 |
| Castillo, A; Mahaffey, E; Majid, DSA; Navar, LG; Prieto, MC | 1 |
| Ahmad, S; Ferrario, CM; Figueroa, JP; Groban, L; Meredith, JW; Saha, A; VonCannon, JL; Wright, KN; Zhang, J | 1 |
| Batlle, D; Danser, AHJ; Denton, KM; Geurts, F; Hassler, L; Hoogduijn, MJ; Hoorn, EJ; Koizumi, M; Li, XC; Lin, H; Matsusaka, T; Mirabito Colafella, KM; Nishiyama, A; Ramkumar, N; Zhuo, JL | 1 |
| Danser, AHJ; Daugherty, A; Foster, D; Garrelds, IM; Hoorn, EJ; Lu, HS; Mirabito Colafella, KM; Nioi, P; Ren, L; Uijl, E; van Veghel, R; Ye, D | 1 |
| Dugas, CM; Franco, M; Katsurada, A; Navar, LG; Satou, R | 1 |
| Daugherty, A; Franklin, MK; Howatt, DA; Lu, HS; Moorleghen, JJ; Mullick, AE; Ohno-Urabe, S; Sawada, H; Ye, D | 1 |
| Hummelgaard, S; Weyer, K | 1 |
| Aicher, BO; Au, DT; Daugherty, A; Franklin, MK; Hampton, B; Howatt, DA; Lu, HS; Migliorini, M; Moorleghen, JJ; Mullick, AE; Muratoglu, SC; Ni, F; Sawada, H; Strickland, DK; Ucuzian, AA; Wang, P; Wani, MM; Zhang, JM | 1 |
| Alenina, N; Bader, M; Qadri, F; Rodrigues, AF; Todiras, M | 1 |
| Fujioka, K; Hattori, T; Hirayama, M; Kagami, S; Kondo, S; Nagai, T; Urushihara, M | 1 |
| Cho, HM; Eto, M; Jung, JK; Kim, JI; Yoon, GE; Youn, EK | 1 |
| Fazan, FS; Gasparini, S; Geerling, JC; Iverson, G; Karthik, S; Peltekian, L; Resch, JM | 1 |
| Angelopoulou, A; Charalampidou, S; Chrousos, GP; Gintoni, I; Papakosta, V; Vassiliou, S; Yapijakis, C | 1 |
| Abuaysheh, S; Dandona, P; Fonseca, V; Ghanim, H; Thethi, TK | 1 |
| Aoki, H; Goto, S; Hosojima, M; Iida, T; Kabasawa, H; Kaseda, R; Kobayashi, R; Komochi, K; Kuwahara, S; Nagatoishi, S; Narita, I; Saito, A; Sawada, R; Takemoto, K; Tsumoto, K; Ugamura, D; Yaoita, E; Yoshida, Y; Yoshizawa, Y | 1 |
| Addison, ML; Ranasinghe, P; Webb, DJ | 1 |
| Cruz-López, EO; Danser, AHJ; Tu, HC; Ye, D; Zlatev, I | 1 |
107 review(s) available for angiotensin ii and angiotensinogen
| Article | Year |
|---|---|
Angiotensin in the brain.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Cerebral Ventricles; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Injections, Intravenous; Injections, Intraventricular; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Saralasin; Subfornical Organ; Thirst | 1978 |
The biochemistry of the renin-angiotensin system and its role in hypertension.
Topics: Aldosterone; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Cattle; Dogs; Endopeptidases; Humans; Hypertension; Peptidyl-Dipeptidase A; Rabbits; Rats; Renin; Swine | 1976 |
Renin-angiotensin system: biochemistry and mechanisms of action.
Topics: Adrenal Glands; Amino Acid Sequence; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Vessels; Brain; Capillary Permeability; Cardiovascular Physiological Phenomena; Catecholamines; Drinking Behavior; Female; Heart Rate; Humans; Kidney; Muscle, Smooth; Nervous System Physiological Phenomena; Peptide Hydrolases; Peptidyl-Dipeptidase A; Renin; Salivary Glands; Steroids; Structure-Activity Relationship; Uterus | 1977 |
[The tonin-angiotensin II system].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Chemical Phenomena; Chemistry, Physical; Drug Synergism; Mesenteric Arteries; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Renin; Saliva; Saralasin; Submandibular Gland; Vasomotor System | 1977 |
Is there a brain renin-angiotensin system?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Blood Pressure; Brain; Humans; Peptidyl-Dipeptidase A; Radioimmunoassay; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin | 1977 |
The renin-angiotensin system.
Topics: Adrenocorticotropic Hormone; Amniotic Fluid; Angiotensin II; Angiotensinogen; Animals; Catecholamines; Central Nervous System; Dogs; Estrogens; Female; Growth Hormone; Humans; Kidney; Pregnancy; Rabbits; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Renin; Sodium; Swine; Sympathetic Nervous System; Vasopressins | 1978 |
The brain renin angiotensin system: a re-evaluation.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Brain Chemistry; Dogs; Drinking Behavior; Injections, Intraventricular; Peptidyl-Dipeptidase A; Rats; Receptors, Angiotensin; Renin; Vasopressins | 1979 |
The renin-angiotensin-aldosterone system. Past, present and future.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Enzyme Precursors; Humans; Mineralocorticoids; Receptors, Angiotensin; Renin; Tissue Distribution | 1978 |
George C. Griffith lecture. The role of renin in normal and pathological cardiovascular homeostasis.
Topics: Angiotensin II; Angiotensinogen; Animals; Antibodies; Blood Pressure; Cardiovascular Physiological Phenomena; Dogs; Feedback; Heart Failure; Homeostasis; Humans; Hypertension, Renal; Posture; Rats; Renin; Water-Electrolyte Balance | 1976 |
Iso-renin of extrarenal origin. "The tissue angiotensinogenase systems".
Topics: Adrenal Glands; Angiotensin II; Angiotensinogen; Animals; Brain; Cells, Cultured; Cerebrospinal Fluid; Female; Humans; Kidney Neoplasms; Mice; Rabbits; Rats; Renin; Submandibular Gland; Uterus | 1976 |
Molecular biology of the vascular renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Humans; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1991 |
Molecular mechanisms of vascular renin-angiotensin system in myointimal hyperplasia.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cell Division; Endothelium, Vascular; Humans; Hyperplasia; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Renin-Angiotensin System | 1991 |
Angiotensin-(1-7): a new hormone of the angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Biotransformation; Humans; Peptide Fragments; Renin; RNA, Messenger | 1991 |
[Expression of the renin and angiotensinogen genes].
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Dexamethasone; Gene Expression Regulation; Humans; Hypertension, Renovascular; Mice; Mice, Transgenic; Organ Specificity; Renin; Renin-Angiotensin System; RNA, Messenger | 1991 |
Immunologic approaches to blockade of the renin-angiotensin system: a review.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Immunization, Passive; Immunotherapy; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1989 |
Multiple pathways of angiotensin production in the blood vessel wall: evidence, possibilities and hypotheses.
Topics: Angiotensin II; Angiotensinogen; Endothelium, Vascular; Humans; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1989 |
The renin-angiotensin-aldosterone system in volume control.
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Body Fluids; Humans; Kidney; Molecular Sequence Data; Renin; Water-Electrolyte Balance | 1989 |
Cellular organization of the brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Brain; Immunohistochemistry; Models, Biological; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1987 |
Brain angiotensin: pathways and pharmacology.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Brain; Hypertension; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1988 |
The dual role of angiotensin and vasopressin as plasma hormones and neuropeptides in cardiovascular regulation.
Topics: Angiotensin II; Angiotensinogen; Animals; Arginine Vasopressin; Blood Pressure; Brain; Brain Mapping; Cardiovascular Physiological Phenomena; Cardiovascular System; Cattle; Desoxycorticosterone; Dogs; Humans; Hypertension; Hypothalamo-Hypophyseal System; Mice; Neurotransmitter Agents; Oxytocin; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride; Subfornical Organ | 1985 |
The renin-angiotensin system and body function.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Brain; Hemorrhage; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Pituitary Gland; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1985 |
Molecular and physiological aspects of tissue renin-angiotensin system: emphasis on cardiovascular control.
Topics: Adrenal Glands; Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Brain; Kidney; Myocardium; Renin; Renin-Angiotensin System | 1988 |
[Genes of blood pressure regulatory factors].
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cloning, Molecular; DNA; Genes; Humans; Hypertension; Kallikreins; Kininogens; Kinins; Renin; Renin-Angiotensin System; RNA, Messenger | 1985 |
Angiotensin-converting enzyme inhibitors: biochemical properties and biological actions.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Heart Failure; Humans; Hypertension; Kidney; Oligopeptides; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Structure-Activity Relationship; Substrate Specificity | 1984 |
[The renin-angiotensin system and drugs].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Diuretics; Humans; Renin; Renin-Angiotensin System; Saralasin | 1982 |
[Renin-angiotensin system blockers].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Humans; Hypertension; Kidney; Oligopeptides; Pepstatins; Renin; Renin-Angiotensin System; Teprotide | 1982 |
Haemodynamic responses to specific renin-angiotensin inhibitors in hypertension and congestive heart failure. A review.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Dipeptides; Enalapril; Heart Failure; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Kinetics; Liver Cirrhosis; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Renin; Renin-Angiotensin System; Teprotide | 1984 |
The brain renin angiotensin system in central cardiovascular control.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Blood Volume; Brain; Brain Chemistry; Captopril; Dogs; Enzyme Inhibitors; Homeostasis; Oligopeptides; Pepstatins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Saralasin; Teprotide | 1984 |
Inhibition of renin: recent developments.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Callithrix; Chemical Phenomena; Chemistry; Dogs; Horses; Humans; Macaca fascicularis; Oligopeptides; Papio; Pepstatins; Rats; Renin; Renin-Angiotensin System; Teprotide | 1984 |
The brain renin--angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Behavior, Animal; Blood Pressure; Brain; Brain Chemistry; Endopeptidases; Humans; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin | 1981 |
The renin-angiotensin system in pregnancy.
Topics: Amniotic Fluid; Angiotensin II; Angiotensinogen; Endopeptidases; Female; Fetal Blood; Fetus; Humans; Hypertension; Juxtaglomerular Apparatus; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins E; Renin; Renin-Angiotensin System | 1981 |
[Ontogeny of the renin-angiotensin-aldosterone system].
Topics: Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Biological Evolution; Cattle; Codon; Dogs; Endocrine Glands; Fishes; Humans; Juxtaglomerular Apparatus; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Species Specificity | 1982 |
[Isorenin--renin-angiotensin system of the brain].
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Endopeptidases; Female; Humans; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Thirst; Vasopressins | 1982 |
[Cerebral renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Cattle; Dogs; Humans; Mice; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Thirst | 1983 |
The endocrinology of pregnancy-induced hypertension.
Topics: Adolescent; Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Estrogens; Female; Humans; Hypertension; Maternal-Fetal Exchange; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Prolactin; Prostaglandins; Renin; Renin-Angiotensin System | 1983 |
The cardiac renin-angiotensin-aldosterone system and hypertensive cardiac hypertrophy.
Topics: Adaptation, Physiological; Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cardiomegaly; Humans; Hypertension; Myocardial Infarction; Myocardium; Renin-Angiotensin System | 1995 |
Molecular basis of human hypertension: the role of angiotensin.
Topics: Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Myocardial Infarction; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1995 |
Angiotensinogen: hormonal regulation and relative importance in the generation of angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Hormones; Kidney; Liver; Renin; Renin-Angiotensin System; RNA, Messenger; Tissue Distribution | 1994 |
Renin-angiotensin system in failing heart.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomyopathies; Collagen; Extracellular Matrix; Gene Expression; Heart; Humans; Myocardium; Reference Values; Renin-Angiotensin System | 1995 |
Tissue angiotensin generation and regulation of vascular tone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cardiovascular Diseases; Humans; Hypertension; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Vascular Resistance; Vasoconstriction | 1995 |
[Growth stimulating properties of angiotensin II on the heart: consequences for therapy of heart failure].
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bradykinin; Gene Expression Regulation; Heart Failure; Hemodynamics; Humans; Hypertrophy, Left Ventricular; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1993 |
The renin-angiotensin system in the brain: an update 1993.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Homeostasis; Humans; Neoplasm Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 1993 |
Ontogeny of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Embryonic and Fetal Development; Gene Expression Regulation; Humans; Kidney; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1993 |
Angiotensin II: biosynthesis, molecular recognition, and signal transduction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cell Division; GTP-Binding Proteins; Humans; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Signal Transduction | 1995 |
Tissue angiotensin II and myocardial infarction.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Collagen; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Rats; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Tissue Distribution; Wound Healing | 1996 |
The role of genetic variants in angiotensin I converting enzyme, angiotensinogen and the angiotensin II type-1 receptor in the pathophysiology of heart muscle disease.
Topics: Angiotensin II; Angiotensinogen; Bradykinin; Cardiac Output, Low; Cardiomegaly; Genetic Variation; Heart Diseases; Humans; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System | 1995 |
[Molecular biology and genetics of angiotensin signal-transduction system].
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Mice; Mice, Knockout; Renin-Angiotensin System; Signal Transduction | 1997 |
[Genetic dissection of protease and signal transduction network].
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Humans; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Pregnancy; Renin-Angiotensin System; Risk Factors; Signal Transduction | 1997 |
Left ventricular hypertrophy in hypertension: etiology, treatment, and controversies.
Topics: Aldosterone; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Risk Factors | 1998 |
[The relationship between genetic polymorphisms and disease, illustrated by the renin-angiotensin-aldosterone system and cardiovascular disease].
Topics: Angiotensin II; Angiotensinogen; Cardiovascular Diseases; Chromosome Mapping; Female; Genetic Markers; Humans; Kidney Diseases; Male; Peptidyl-Dipeptidase A; Point Mutation; Polymorphism, Genetic; Receptors, Angiotensin; Renin-Angiotensin System; Spondylitis, Ankylosing | 1998 |
[The auto- and endocrine function of the adipose tissue. Significance for metabolic complications in obesity].
Topics: Adipose Tissue; Angiotensin II; Angiotensinogen; Fatty Acids, Nonesterified; Gonadal Steroid Hormones; Growth Substances; Humans; Obesity; Plasminogen Activator Inhibitor 1; Prostaglandins; Tumor Necrosis Factor-alpha | 1998 |
Concentrations and actions of intraluminal angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Biological Transport; Biopsy, Needle; Body Fluids; Cell Membrane; Cells, Cultured; Epithelial Cells; Kidney Tubules, Distal; Kidney Tubules, Proximal; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Hypertension-induced end-organ damage : A new transgenic approach to an old problem.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Coronary Circulation; Humans; Hypertension; Kidney; Models, Cardiovascular; Myocardium; Rats; Renal Circulation; Renin | 1999 |
Seven lessons from two candidate genes in human essential hypertension: angiotensinogen and epithelial sodium channel.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet; Diet, Sodium-Restricted; Epithelial Sodium Channels; Genetic Variation; Genotype; Humans; Hypertension; Rats; Renal Circulation; Sodium Channels | 1999 |
The cardiac renin-angiotensin system: conceptual, or a regulator of cardiac function?
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cardiac Output, Low; Heart; Humans; Myocardium; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1999 |
Is there a local renin-angiotensin system in the heart?
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Cell Membrane; Cells, Cultured; Humans; Intracellular Fluid; Mannosephosphates; Myocardium; Peptidyl-Dipeptidase A; Perfusion; Renin; Renin-Angiotensin System | 1999 |
Transgenic and knockout mice to study the renin-angiotensin system and other interacting vasoactive pathways.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Humans; Hypertension; Mice; Mice, Knockout; Mice, Transgenic; Nitric Oxide; Peptidyl-Dipeptidase A; Receptors, Dopamine; Receptors, Neuropeptide; Renin-Angiotensin System | 2000 |
Adipose tissue as an endocrine organ.
Topics: Adipose Tissue; Angiotensin II; Angiotensinogen; Endocrine Glands; Epoprostenol; Estrogens; Female; Gonadal Steroid Hormones; Humans; Lipid Metabolism; Male | 2000 |
[Renin-angiotensin-aldosterone system in thyroid disorders].
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Humans; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Thyroid Diseases | 2000 |
Angiotensinogen, angiotensin II and adipose tissue development.
Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Epoprostenol; Gene Expression Regulation; Humans; Obesity | 2000 |
Angiotensin II-generating enzymes.
Topics: Angiotensin II; Angiotensinogen; Animals; Cathepsin G; Cathepsins; Chymases; Chymotrypsin; Humans; Hydrogen-Ion Concentration; Models, Biological; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Serine; Serine Endopeptidases; Tissue Kallikreins | 2000 |
Current genetics of essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
Angiotensinogen in essential hypertension: from genetics to nephrology.
Topics: Alleles; Angiotensin II; Angiotensinogen; Female; Genetic Linkage; Genetic Variation; Haplotypes; Homeostasis; Humans; Hypertension; Japan; Male; Models, Genetic; Nephrons; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Promoter Regions, Genetic; Renin-Angiotensin System | 2001 |
Regulation of intrarenal angiotensin II in hypertension.
Topics: Angiotensin II; Angiotensinogen; Humans; Hypertension; Kidney; Kidney Tubules; Receptors, Angiotensin | 2002 |
[History of nephrology in the past 100 years: Japanese contribution to studies on the renin-angiotensin system].
Topics: Angiotensin II; Angiotensinogen; Animals; Gene Deletion; Gene Transfer Techniques; History, 20th Century; Humans; Japan; Mice; Mice, Knockout; Nephrology; Renin; Renin-Angiotensin System | 2002 |
Angiotensinogen, adipocyte differentiation and fat mass enlargement.
Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Humans; Mice; Rats; Receptors, Angiotensin; Serine Proteinase Inhibitors; Vasoconstrictor Agents | 2002 |
The adipose-tissue renin-angiotensin-aldosterone system: role in the metabolic syndrome?
Topics: Adipocytes; Adipose Tissue, Brown; Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Insulin Resistance; Metabolic Syndrome; Mice; Obesity; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Thermogenesis | 2003 |
The chronic inflammatory hypothesis for the morbidity associated with morbid obesity: implications and effects of weight loss.
Topics: Acute-Phase Proteins; Adipose Tissue; Angiotensin II; Angiotensinogen; C-Reactive Protein; Humans; Inflammation; Insulin Resistance; Interleukin-6; Liver; Lymphotoxin-alpha; Morbidity; Obesity; Tumor Necrosis Factor-alpha; Weight Loss | 2004 |
Renal renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Kidney Tubules; Nitric Oxide; Renin-Angiotensin System | 2004 |
Working outside the system: an update on the unconventional behavior of the renin-angiotensin system components.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Carboxypeptidases; Humans; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Signal Transduction | 2005 |
Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fibrosis; Humans; Hyperglycemia; Hypoglycemia; Islets of Langerhans; Pancreas; Peptidyl-Dipeptidase A; PPAR gamma; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2006 |
The intracellular renin-angiotensin system: a new paradigm.
Topics: Angiotensin II; Angiotensinogen; Animals; Chymases; Humans; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2007 |
Effects of hormone therapy on blood pressure and the renin-angiotensin system in postmenopausal women.
Topics: Angiotensin II; Angiotensinogen; Blood Pressure; Estrogen Replacement Therapy; Female; Genotype; Humans; Postmenopause; Renal Circulation; Renin; Renin-Angiotensin System; Risk Factors | 2007 |
The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Chronic Disease; Disease Models, Animal; Humans; Hypertension; Hypertension, Renal; Kidney; Kidney Diseases; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2007 |
The renin-angiotensin system and diabetes: an update.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Diabetes Mellitus; Endothelium, Vascular; Humans; Hyaluronan Receptors; Insulin; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Signal Transduction | 2008 |
[Hot topics in renal physiology].
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Kidney; Kidney Glomerulus; Microscopy, Fluorescence, Multiphoton; Physiology; Renin | 2009 |
Activated intrarenal reactive oxygen species and renin angiotensin system in IgA nephropathy.
Topics: Aldehydes; Angiotensin II; Angiotensinogen; Animals; Biomarkers; Cysteine Proteinase Inhibitors; Evidence-Based Medicine; Glomerulonephritis, IGA; Heme Oxygenase-1; Humans; Mice; Reactive Oxygen Species; Renin-Angiotensin System; Vasoconstrictor Agents | 2009 |
Antagonists of the renin-angiotensin system and the prevention of obesity.
Topics: Adipose Tissue; Adiposity; Angiotensin II; Angiotensinogen; Animals; Body Weight; Disease Models, Animal; Humans; Obesity; Receptors, Angiotensin; Renin-Angiotensin System | 2009 |
[Intrarenal mechanisms of angiotensin II formation].
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Biomarkers; Humans; Hypertension; Kidney; Kidney Diseases; Peptidyl-Dipeptidase A; Prorenin Receptor; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Serine Proteases | 2010 |
Angiotensin II, tissue factor and the thrombotic paradox of hypertension.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Endothelium, Vascular; Humans; Hypertension; Renin; Renin-Angiotensin System; Risk Factors; Thromboplastin; Thrombosis | 2010 |
Transgenic rats: tools to study the function of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Models, Animal; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System | 1996 |
Intrarenal angiotensin II and its contribution to the genesis of chronic hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Chronic Disease; Humans; Hypertension; Kidney; Kidney Tubules, Collecting; Prorenin Receptor; Receptors, Cell Surface; Renin | 2011 |
Evolving concepts on regulation and function of renin in distal nephron.
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Kidney Tubules, Distal; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Sodium | 2013 |
Non-ACE pathway-induced angiotensin II production.
Topics: Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Chymases; Humans; Myocardium; Serine Endopeptidases | 2013 |
The renin angiotensin aldosterone system and insulin resistance in humans.
Topics: Adipose Tissue; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Glucose; Hemodynamics; Humans; Insulin Resistance; Models, Animal; Muscle, Skeletal; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2013 |
An evolving story of angiotensin-II-forming pathways in rodents and humans.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Humans; Molecular Sequence Data; Rodentia | 2014 |
Roles of collecting duct renin and (pro)renin receptor in hypertension: mini review.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Hypertension; Kidney Diseases; Peptidyl-Dipeptidase A; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases | 2015 |
Role of stimulated intrarenal angiotensinogen in hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Biological Transport; Humans; Hypertension; Kidney Diseases; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sodium; Vasoconstriction | 2015 |
Angiotensins and Their Receptors in Cardiac and Vascular Injury.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Cardiovascular Diseases; Clinical Trials, Phase III as Topic; Humans; Hypertension; Renin-Angiotensin System | 2016 |
Intracrine angiotensin II functions originate from noncanonical pathways in the human heart.
Topics: Angiotensin II; Angiotensinogen; Animals; Chymases; Heart; Humans; Myocardium; Peptide Fragments; Renin-Angiotensin System; Vascular Remodeling; Ventricular Remodeling | 2016 |
An Expanded View of Progressive Cardiorenal Disorders.
Topics: Angiotensin II; Angiotensinogen; Cardio-Renal Syndrome; Disease Progression; Heart Failure; Humans; Parathyroid Hormone-Related Protein; Peptidyl-Dipeptidase A; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A | 2016 |
Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Humans; Hypertension; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Male; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; Sodium; Sodium-Hydrogen Exchangers; Up-Regulation; Vacuolar Proton-Translocating ATPases | 2016 |
Role of the intrarenal renin-angiotensin system in the progression of renal disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Biomarkers; Disease Progression; Humans; Kidney; Kidney Diseases; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction | 2017 |
Role of Tissue Renin-angiotensin System and the Chymase/angiotensin-( 1-12) Axis in the Pathogenesis of Diabetic Retinopathy.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Chymases; Diabetic Retinopathy; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
How Is the Brain Renin-Angiotensin System Regulated?
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Humans; Peptidyl-Dipeptidase A; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases | 2017 |
Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Peptide Fragments; Protective Factors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2018 |
Immunologic and endocrine functions of adipose tissue: implications for kidney disease.
Topics: Adipokines; Adiponectin; Adipose Tissue; AMP-Activated Protein Kinases; Angiotensin II; Angiotensinogen; Ceramidases; Diabetes Mellitus, Type 2; Humans; Inflammation; Kidney Diseases; Leptin; Macrophages; Obesity; Receptors, Adiponectin; Signal Transduction | 2018 |
Independent regulation of renin-angiotensin-aldosterone system in the kidney.
Topics: Angiotensin II; Angiotensinogen; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Kidney; Kidney Diseases; Renin; Renin-Angiotensin System | 2018 |
Renin-Angiotensin System and Cardiovascular Functions.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiovascular Diseases; Cardiovascular System; Hemodynamics; Humans; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Signal Transduction; Ventricular Function | 2018 |
Intratubular and intracellular renin-angiotensin system in the kidney: a unifying perspective in blood pressure control.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Humans; Kidney; Kidney Tubules, Proximal; Liver; Mice; Renin; Renin-Angiotensin System | 2018 |
Megalin: a Novel Determinant of Renin-Angiotensin System Activity in the Kidney?
Topics: Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Kidney; Low Density Lipoprotein Receptor-Related Protein-2; Mice; Renin; Renin-Angiotensin System | 2020 |
The Angiotensin-(1-12)/Chymase axis as an alternate component of the tissue renin angiotensin system.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biocatalysis; Bone Marrow; Brain; Cardiovascular Diseases; Chymases; Gene Expression; Humans; Intestines; Kidney; Myocardium; Peptide Fragments; Rats; Renin-Angiotensin System | 2021 |
DNA Methylation of the Angiotensinogen Gene,
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cardiovascular Diseases; CCAAT-Enhancer-Binding Proteins; Cytochrome P-450 CYP11B2; DNA Methylation; Epigenesis, Genetic; Gene Expression; Gene Expression Regulation; Humans; Hypertension; Promoter Regions, Genetic; Transcription Factors | 2021 |
Kidney Angiotensin in Cardiovascular Disease: Formation and Drug Targeting.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Cardiovascular Diseases; Drug Delivery Systems; Female; Humans; Kidney; Male; Renin; Renin-Angiotensin System; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Megalin-Mediated Endocytosis in the Kidney Proximal Tubule: Relevance to Regulation of the Renal Renin-Angiotensin System.
Topics: Angiotensin II; Angiotensinogen; Endocytosis; Humans; Kidney; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; Renin; Renin-Angiotensin System | 2023 |
Novel Pharmacological Approaches in the Treatment of Hypertension: A Focus on RNA-Based Therapeutics.
Topics: Angiotensin II; Angiotensinogen; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Humans; Hypertension; Renin-Angiotensin System; RNA, Small Interfering | 2023 |
Targeting Angiotensinogen With
Topics: Acetylgalactosamine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Humans; Hypertension; Renin; Renin-Angiotensin System; RNA, Small Interfering | 2023 |
8 trial(s) available for angiotensin ii and angiotensinogen
| Article | Year |
|---|---|
Severe hypotension with bradycardia during renin inhibition with H142 in sodium deplete man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Bradycardia; Dose-Response Relationship, Drug; Epinephrine; Hemodynamics; Humans; Hypotension; Infusions, Intravenous; Male; Norepinephrine; Randomized Controlled Trials as Topic; Renin; Sodium | 1989 |
The renin-angiotensin system during converting enzyme inhibition with captopril in patients with severe treatment-resistant hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol; Renin; Renin-Angiotensin System | 1984 |
Relationship between polymorphism in the angiotensinogen, angiotensin-converting enzyme or angiotensin II receptor and renal progression in Japanese NIDDM patients.
Topics: Aged; Angiotensin II; Angiotensinogen; Diabetes Mellitus, Type 2; Disease Progression; DNA; Female; Genotype; Humans; Japan; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Angiotensin | 1999 |
Renal response to captopril reflects state of local renin system in healthy humans.
Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Female; Humans; Male; Middle Aged; p-Aminohippuric Acid; Renal Circulation; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilation | 1999 |
Angiotensinogen genotype affects renal and adrenal responses to angiotensin II in essential hypertension.
Topics: Adolescent; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Antihypertensive Agents; Female; Genotype; Humans; Hypertension; Kidney; Male; Middle Aged; Models, Biological; Renal Plasma Flow | 2002 |
Genetic factors associated with volume-sensitive hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Blood Volume; Calmodulin-Binding Proteins; Diet, Sodium-Restricted; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Phenotype; Predictive Value of Tests; Renin; Renin-Angiotensin System; Sex Factors; Vasoconstrictor Agents | 2004 |
Actions by angiotensin II on esophageal contractility in humans.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Benzimidazoles; Biphenyl Compounds; Esophageal Sphincter, Lower; Esophagus; Female; Gene Expression; Humans; In Vitro Techniques; Male; Manometry; Middle Aged; Muscle Contraction; Peptidyl-Dipeptidase A; Peristalsis; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Vasoconstrictor Agents | 2007 |
Urinary angiotensinogen as a marker of intrarenal angiotensin II activity associated with deterioration of renal function in patients with chronic kidney disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Antihypertensive Agents; Biomarkers; Collagen Type I; Female; Humans; Kidney; Losartan; Male; Middle Aged; Renal Insufficiency, Chronic | 2007 |
662 other study(ies) available for angiotensin ii and angiotensinogen
| Article | Year |
|---|---|
Methodologic problems in plasma renin activity measurements.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Angiotensin II; Angiotensinogen; Dimercaprol; Humans; Hydrogen-Ion Concentration; Hypertension; Isoflurophate; Methods; Middle Aged; Oxyquinoline; Posture; Protease Inhibitors; Radioimmunoassay; Renin; Time Factors | 1976 |
Plasma prorenin: cryoactivation and relationship to renin substrate in normal subjects.
Topics: Angiotensin II; Angiotensinogen; Cold Temperature; Female; Freezing; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Kidney; Male; Renin; Time Factors | 1976 |
Human angiotensinogen. Purification partial characterization, and a comparison with animal prohormones.
Topics: Angiotensin II; Angiotensinogen; Animals; Biological Assay; Chromatography, Affinity; Drug Stability; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Kidney; Kinetics; Molecular Weight; Rabbits; Renin; Species Specificity | 1977 |
New developments in our knowledge of the chemistry of renin.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Molecular Weight; Renin; Species Specificity; Structure-Activity Relationship; Submandibular Gland | 1977 |
An inactive renin in human plasma.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cattle; Diet; Enzyme Activation; Female; Freezing; Humans; Hydrogen-Ion Concentration; Hypertension, Renal; Male; Pregnancy; Renin; Saralasin; Sodium | 1977 |
Conformations of synthetic tetradecapeptide renin substrate and of angiotensin I in aqueous solution.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Circular Dichroism; Hydrogen-Ion Concentration; Protein Conformation; Renin; Solubility; Spectrophotometry, Infrared | 1977 |
Formation of vasoactive substances by trypsin--effect of pH differences on the generation.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Biological Assay; Blood Pressure; Female; Humans; Hydrogen-Ion Concentration; Rats; Trypsin; Uterine Contraction; Vasoconstrictor Agents | 1977 |
An international collaborative study of renin assay: establishment of the international reference preparation of human renin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Biological Assay; Humans; Hydrogen-Ion Concentration; Radioimmunoassay; Reference Values; Renin | 1975 |
The renin-angiotensin system in pregnancy.
Topics: Angiotensin II; Angiotensinogen; Blood Pressure; Chorion; Endopeptidases; Female; Humans; Kidney; Pre-Eclampsia; Pregnancy; Renin; Uterus | 1975 |
[The renin-angiotensin-aldosterone system in parenchymatous liver diseases].
Topics: Acute Kidney Injury; Aldosterone; Angiotensin II; Angiotensinogen; Ascites; Blood Pressure; Endopeptidases; Humans; Liver Diseases; Renin | 1976 |
Renin substrate in granules from rat kidney cortex.
Topics: Angiotensin II; Angiotensinogen; Animals; Cytoplasmic Granules; Endopeptidases; In Vitro Techniques; Kidney Cortex; Liver; Models, Biological; Molecular Weight; Rats; Renin | 1976 |
[Various historical details and topical aspects of the structure of renin-angiotensin system].
Topics: Angiotensin II; Angiotensinogen; Kinetics; Peptidyl-Dipeptidase A; Renin | 1976 |
The renin-angiotensin system and sodium excretion during gestation.
Topics: Angiotensin II; Angiotensinogen; Endopeptidases; Female; Fetal Blood; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular; Renin; Sodium | 1976 |
Developmental correlation of higher levels of estrogen binding by macromolecules in rat liver supernatant and of increases in plasma renin substrate levels after estrogen administration.
Topics: 4-Chloromercuribenzenesulfonate; Angiotensin II; Angiotensinogen; Animals; Dexamethasone; Diethylstilbestrol; Ethinyl Estradiol; Female; In Vitro Techniques; Liver; Protein Binding; Rats; Sexual Maturation; Uterus | 1977 |
The effect of conjugated estrogens on the renin-angiotensin system.
Topics: Adult; Angiotensin II; Angiotensinogen; Blood Pressure; Creatinine; Estrogens, Conjugated (USP); Female; Humans; Male; Renin; Sodium | 1977 |
Evidence for an endogenous brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Cathepsins; Cattle; Dogs; Humans; Peptidyl-Dipeptidase A; Rabbits; Radioimmunoassay; Rats; Receptors, Angiotensin; Renin | 1979 |
[Humoral mechanisms of renin-angiotensin system activation in macrofocal myocardial infarct].
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Endopeptidases; Enzyme Activation; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Norepinephrine; Renin; Shock, Cardiogenic | 1979 |
"Prorenin" in human plasma?
Topics: Angiotensin II; Angiotensinogen; Drug Storage; Enzyme Activation; Enzyme Precursors; Female; Freezing; Humans; Hydrogen-Ion Concentration; Hypertension; In Vitro Techniques; Male; Renin; Sodium; Time Factors | 1975 |
Purification, properties and kinetics of sheep and human renin substrates.
Topics: Angiotensin II; Angiotensinogen; Animals; Biological Assay; Blood Pressure; Chromatography, DEAE-Cellulose; Chromatography, Gel; Contraceptives, Oral; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Nephrectomy; Pepsin A; Pregnancy; Rats; Renin; Sheep; Swine | 1975 |
Plasma renin, renin substrate and angiotensin II changes following experimental endotoxinaemia.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Corticosterone; Endotoxins; Escherichia coli; Male; Rats; Renin | 1979 |
Blood pressure effects of endogenous brain angiotensin in rats are increased by inhibition of prostaglandin biosynthesis.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Indomethacin; Male; Nephrectomy; Rats; Renin | 1979 |
An association between the renin angiotensin system, blood pressure and potassium intake.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Humans; Hypertension; Potassium; Renin | 1980 |
Renin-angiotensin system in phlorhizin compared with alloxan diabetes in the rat.
Topics: Alloxan; Angiotensin II; Angiotensinogen; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Kidney; Male; Phlorhizin; Rats; Renin; Water-Electrolyte Balance | 1979 |
Mechanism of the dipsogenic action of tetradecapeptide renin substrate in dogs.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Dogs; Dose-Response Relationship, Drug; Drinking Behavior; Female; Male; Pepstatins; Peptides; Saralasin | 1979 |
[Physiology of the renin-angiotensin system].
Topics: Aldosterone; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Chromaffin System; Humans; Kidney; Muscle Contraction; Renin; Sodium | 1979 |
The effect of angiotensin II infusion and of bilateral nephrectomy on plasma renin--substrate in rats.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Injections; Male; Nephrectomy; Rats | 1978 |
[Renin inhibitory factor in renal hypertension--an attempt in determining renin inhibitory capacity of the plasma].
Topics: Angiotensin II; Angiotensinogen; Animals; Dogs; Hypertension, Renal; Renin | 1977 |
In mice aggressive behavior provokes vast increase in plasma renin concentration, causing only slight, if any, increase in blood pressure.
Topics: Aggression; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Kidney; Male; Mice; Nephrectomy; Norepinephrine; Renin; Saralasin; Secretory Rate; Social Isolation; Submandibular Gland; Time Factors | 1979 |
Clinical, biochemical and pathological features of low-renin ("primary") hyperaldosteronism.
Topics: 18-Hydroxydesoxycorticosterone; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aging; Angiotensin II; Angiotensinogen; Carbon Dioxide; Corticosterone; Desoxycorticosterone; Female; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Potassium; Renin; Sodium; Urea; Vascular Diseases | 1978 |
Studies on the activity of the renin-angiotensin-aldosterone system (RAAS) in patients with cirrhosis of the liver.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Ascites; Diuretics; Humans; Liver Cirrhosis; Middle Aged; Renin | 1978 |
Systemic angiotensin-induced drinking in the dog: a physiological phenomenon.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Carotid Arteries; Dogs; Dose-Response Relationship, Drug; Drinking; Female; Heart Rate; Injections, Intra-Arterial; Injections, Intravenous; Male; Pulse; Renin | 1978 |
Autoregulation of plasma flow in the isolated perfused rat kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Epinephrine; Female; Homeostasis; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Regional Blood Flow; Serum Albumin; Vascular Resistance | 1978 |
Mechanism of the dipsogenic action of tetradecapeptide renin substrate.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Brain; Drinking; Injections, Intraventricular; Male; Pepstatins; Premedication; Rats; Renin; Teprotide | 1978 |
In vivo enzyme activity of purified human brain renin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Cathepsins; Humans; Injections, Intraventricular; Male; Rats; Renin | 1978 |
Effect of exogenous and endogenous angiotensin II in the isolated perfused rat kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Saralasin; Teprotide; Vasomotor System | 1978 |
Angiotensin II concentration in cerebrospinal fluid after intraventricular injection of angiotensinogen or renin.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Dogs; Female; Injections, Intraventricular; Male; Renin | 1978 |
Evidence for an angiotensinogenic mechanism of the hypertension of Cushing's syndrome.
Topics: Adrenal Glands; Adrenalectomy; Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cushing Syndrome; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Renin; Saralasin | 1978 |
A circulating renin activator in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Contraceptives, Oral; Diuretics; Enzyme Activation; Functional Laterality; Haplorhini; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Kinetics; Renal Artery Obstruction; Renin; Sodium; Spironolactone | 1975 |
Purification and partial characterization of human angiotensinogen.
Topics: Amino Acids; Angiotensin II; Angiotensinogen; Electrophoresis, Polyacrylamide Gel; Humans; Immunodiffusion; Immunoelectrophoresis; Renin | 1976 |
Elevation of plasma renin activity during avoidance performance in baboons.
Topics: Angiotensin II; Angiotensinogen; Animals; Avoidance Learning; Haplorhini; Male; Papio; Renin; Time Factors | 1976 |
Separation of human renin substrate from renin and a major contaminating albumin using a concanavalin A-sepharose column.
Topics: Angiotensin II; Angiotensinogen; Chromatography, Agarose; Concanavalin A; Humans; Methods; Renin; Serum Albumin | 1977 |
Dithiothreitol augments renin activity by an action on renin substrate.
Topics: Angiotensin II; Angiotensinogen; Animals; Binding Sites; Cattle; Dithiothreitol; Drug Synergism; Ethylmaleimide; Kinetics; Renin | 1977 |
Effect of angiotensin II and glucocorticoids on plasma angiotensinogen concentration in the dog.
Topics: Adrenal Cortex Hormones; Angiotensin II; Angiotensinogen; Animals; Dogs; Hematocrit; Hydrocortisone; Hypophysectomy; Infusions, Parenteral; Injections, Intraventricular; Male; Pregnanes; Renin | 1977 |
Effect of norethisterone-acetate on salt excretion and of the renin-aldosterone system in man.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Glucuronates; Humans; Male; Norethindrone; Renin; Sodium | 1977 |
Synthesis of angiotensinogen by isolated rat liver cells and its regulation in comparison to serum albumin.
Topics: Angiotensin II; Angiotensinogen; Animals; In Vitro Techniques; Kinetics; Leucine; Liver; Male; Protein Biosynthesis; Radioimmunoassay; Rats; Serum Albumin | 1977 |
Action of a human plasma fraction on tetradecapeptide, angiotensin I and angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Blood Protein Electrophoresis; Blood Proteins; Chromatography, Gel; Humans; In Vitro Techniques; Radioimmunoassay; Renin; Time Factors | 1977 |
Testosterone effect on renin system in rats.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Body Weight; Castration; Female; Male; Rats; Renin; Testosterone | 1977 |
An improved method for the assay of renin secreted from kidney slices.
Topics: Angiotensin II; Angiotensinogen; Animals; Cross Reactions; In Vitro Techniques; Isoproterenol; Kidney; Kinetics; Methods; Radioimmunoassay; Rats; Renin | 1977 |
Efficacy of different components of the renin-angiotensin system in eliciting drinking in the dog; comparison with rat and pigeon [proceedings].
Topics: Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Columbidae; Dogs; Drinking; Rats | 1977 |
Effect of propranolol on renin release in the dog.
Topics: Aldosterone; Anesthesia; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dogs; Female; Heart Rate; Potassium; Propranolol; Renin; Sodium; Sodium Chloride; Time Factors | 1977 |
Partial purification of human renin substrate.
Topics: Angiotensin II; Angiotensinogen; Blood Proteins; Chromatography, Affinity; Drug Stability; Female; Humans; Immunoelectrophoresis; Kinetics; Methods | 1976 |
Control of mineralocorticoid substitution in Addison's disease by plasma renin measurement.
Topics: Addison Disease; Angiotensin II; Angiotensinogen; Dexamethasone; Drug Administration Schedule; Fludrocortisone; Humans; Hydrocortisone; Mineralocorticoids; Renin | 1976 |
Changes of plasma renin substrate concentration in rats under various experimental conditions.
Topics: Angiotensin II; Angiotensinogen; Animals; Estradiol; Female; Ligation; Nephrectomy; Rats; Ureter | 1976 |
Isolation of human angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Electrophoresis, Polyacrylamide Gel; Humans; Immunoelectrophoresis; Methods; Renin | 1976 |
Renin response and angiotensinogen control during graded hemorrhage and shock in the dog.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dogs; Feedback; Female; Kidney; Liver; Male; Renin; Saralasin; Shock, Hemorrhagic; Vasomotor System | 1976 |
The influence of nephrectomy, ureteral ligation, and of estradiol on plasma renin substrate in unilaterally nephrectomized rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Estradiol; Female; Ligation; Nephrectomy; Rats; Renin; Ureter | 1976 |
Effects of ethinylestradiol on the renin-angiotensin-aldosterone-system and on plasma transcortin in women and men.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Ethinyl Estradiol; Female; Humans; Male; Renin; Sex Factors; Transcortin | 1976 |
Acupuncture therapy in patients with chronic disabling pain.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Male; Portacaval Shunt, Surgical; Rats; Renin | 1976 |
Plasma renin substrate and blood pressure after protacaval anastomosis.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Portacaval Shunt, Surgical; Rats | 1976 |
Further evidence for the existence of angiotensinogen stimulating activity (ASA) after nephrectomy.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood; Liver; Nephrectomy; Rats; Renin | 1976 |
Heterogeneity of renin substrate in human plasma: effect of pregnancy and oral contraceptives.
Topics: Angiotensin II; Angiotensinogen; Contraceptives, Oral; Electrophoresis, Polyacrylamide Gel; Female; Humans; Liver Cirrhosis; Male; Nephrectomy; Pregnancy | 1976 |
Simultaneous measurement of renin and renin substrate concentration in human plasma by a simple kinetic method.
Topics: Angiotensin II; Angiotensinogen; Female; Furosemide; Humans; Kinetics; Pregnancy; Radioimmunoassay; Renin | 1976 |
Studies of the renin-angiotension-aldosterone system, cortisol, DOC, and ADH in normal and hypertensive pregnancy.
Topics: Adrenal Cortex Hormones; Aldosterone; Angiotensin II; Angiotensinogen; Arginine Vasopressin; Corticosterone; Desoxycorticosterone; Female; Humans; Hydrocortisone; Hypertension; Ovulation; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, First; Renin; Sodium; Vasopressins | 1976 |
Sequential changes in the renin--angiotensin--aldosterone systems and plasma progesterone concentration in normal and abnormal human pregnancy.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Progesterone; Renin | 1976 |
The renin-angiotensin system in mother and fetus at cesarean section: a preliminary communication.
Topics: Adolescent; Adult; Angiotensin II; Angiotensinogen; Arteries; Cesarean Section; Female; Fetal Blood; Humans; Lysine Carboxypeptidase; Pregnancy; Renin; Veins | 1976 |
The use of saralasin to evaluate the function of the brain renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Dogs; Drinking; Hypertension; Rats; Renin; Saralasin; Swine; Vasopressins | 1976 |
Renin, renin substrate and angiotensin II concentration in renal venous blood.
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Blood Pressure; Female; Furosemide; Humans; Hypertension, Renal; Male; Middle Aged; Renal Artery Obstruction; Renal Veins; Renin; Stimulation, Chemical; Vena Cava, Inferior | 1976 |
[Hyperaldosteronism in acute viral hepatitis, liver cirrhosis and fulminating liver failure].
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Corticosterone; Hepatic Encephalopathy; Hepatitis; Humans; Hydrocortisone; Hyperaldosteronism; Liver Cirrhosis; Liver Diseases; Renin | 1976 |
Evidence against inhibition of the renin-angiotensinogen reaction by des-angiotensin substrate in the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Male; Rats; Renin | 1976 |
Plasma angiotensin II, renin, renin-substrate and aldosterone concentrations in acute renal failure in man.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Male; Middle Aged; Peritoneal Dialysis; Potassium; Renal Dialysis; Renin; Sodium | 1975 |
Evidence for the existence of an acetone soluble renin inhibiting factor in normal human plasma.
Topics: Acetone; Angiotensin II; Angiotensinogen; Humans; Hypertension; In Vitro Techniques; Kinetics; Radioimmunoassay; Renin; Solubility; Time Factors; Uremia | 1975 |
Angiotensin III: (DES-Aspartic Acid-1)-Angiotensin II. Evidence and speculation for its role as an important agonist in the renin - angiotensin system.
Topics: Adrenal Cortex; Aldosterone; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Aspartic Acid; Binding, Competitive; Drug Synergism; Feedback; Models, Biological; Molecular Conformation; Rats; Receptors, Drug; Renin; Structure-Activity Relationship | 1975 |
Laxative-induced hypokalemia, sodium depletion and hyperreninemia. Effects of potassium and sodium replacement on the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Cathartics; Dose-Response Relationship, Drug; Female; Humans; Hypokalemia; Middle Aged; Potassium; Radioimmunoassay; Renin; Sodium; Substance-Related Disorders; Water-Electrolyte Balance | 1975 |
[Studies on the renin-angiotensin system in adrenal regeneration hypertension (author's transl)].
Topics: Adrenal Glands; Adrenal Medulla; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Female; Furosemide; Hypertension; Kidney; Male; Organ Size; Potassium; Rats; Regeneration; Renin; Sodium; Sodium Chloride | 1975 |
Effects of unilateral nephrectomy on plasma renin substrate and renin concentration in rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Nephrectomy; Rats; Renin; Time Factors | 1975 |
The effects of intracerebroventricular administration of renin on drinking and blood pressure.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dogs; Drinking; Female; Male; Renin | 1975 |
Synthesis of lysophosphatidylethanolamine analogs that inhibit renin activity.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Depression, Chemical; Dogs; Hypertension; In Vitro Techniques; Lysophospholipids; Phosphatidylethanolamines; Rats; Renin; Structure-Activity Relationship | 1975 |
Measurement of renin concenration in human plasma using 125i-labelled sheep renin substrate.
Topics: Angiotensin II; Angiotensinogen; Biological Assay; Charcoal; Humans; Iodine Radioisotopes; Kidney Diseases; Kinetics; Nephrectomy; Renin | 1975 |
Oral contraceptive pill hypertension.
Topics: Adolescent; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Body Weight; Contraceptives, Oral; Diuresis; Estrogens; Female; Hemodynamics; Humans; Hypertension; Natriuresis; Pituitary-Adrenal System; Renin; Sodium; Sympathetic Nervous System | 1975 |
Changes of plasma renin, angiotensin II and renin substrate during reversal of malignant renovascular hypertension.
Topics: Angiotensin II; Angiotensinogen; Humans; Hypertension, Malignant; Hypertension, Renal; Male; Middle Aged; Nephrectomy; Renal Artery Obstruction; Renin | 1975 |
Renin substrate in plasma of various mammalian species: electrophoresis on polyacrylamide gel.
Topics: Angiotensin II; Angiotensinogen; Animals; Cattle; Dogs; Electrophoresis, Polyacrylamide Gel; Humans; Mice; Rabbits; Rats; Sheep; Species Specificity; Swine | 1975 |
[Angiotensinogen synthesis rate of the isolation-perfused rat liver in experimental liver damage].
Topics: Angiotensin II; Angiotensinogen; Animals; Liver; Liver Cirrhosis, Experimental; Male; Perfusion; Rats | 1975 |
[Presence of a renin inhibitor in the plasma of intact dogs].
Topics: Angiotensin II; Angiotensinogen; Animals; Clinical Enzyme Tests; Dogs; Mathematics; Renin | 1975 |
The role of renin in renal failure associated with hepatic failure.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensinogen; Humans; Liver Diseases; Renin | 1975 |
Effect of the protein-synthesis inhibitor actinomycin-D on the renin-angiotensin system in the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Dactinomycin; Heart; Kidney; Male; Organ Size; Rats; Renin | 1975 |
The renin-angiotensin system in rats with hereditary hydronephrosis.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Female; Hydronephrosis; Hyperkalemia; Kidney; Male; Organ Size; Rats; Renin; Sodium | 1975 |
[Proceedings: Cyclic changes of renin activity, renin substrate concentration and serum aldosterone concentration in the female].
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Menstruation; Renin; Time Factors | 1975 |
Longitudinal study of platelet angiotensin II binding in human pregnancy.
Topics: Angiotensin II; Angiotensinogen; Blood Platelets; Down-Regulation; Female; Humans; Longitudinal Studies; Postpartum Period; Pregnancy; Renin; Time Factors | 1992 |
Peripheral and central angiotensin II regulates expression of genes of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Brain; Gene Expression Regulation; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Liver; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; RNA, Messenger; Tissue Distribution | 1992 |
Increased vascular formation of angiotensin II in one-kidney, one clip hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood Vessels; Captopril; Enalapril; Hypertension, Renovascular; In Vitro Techniques; Male; Mesenteric Arteries; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Reference Values; Saralasin | 1992 |
Tonin-like activity present in the human submandibular gland.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Humans; Molecular Sequence Data; Molecular Weight; Peptidyl-Dipeptidase A; Submandibular Gland; Substrate Specificity | 1992 |
Local generation and action of angiotensin II in dog iris sphincter muscle.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Iris; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A | 1992 |
Stimulation of prolactin secretion from rat pituitary by luteinizing hormone-releasing hormone: evidence against mediation by angiotensin II acting through a (Sar1-Ala8)-angiotensin II-sensitive receptor.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Biphenyl Compounds; Captopril; Cells, Cultured; Female; Gonadotropin-Releasing Hormone; Imidazoles; Losartan; Male; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles | 1992 |
Colocalization and release of angiotensin and renin in renal cortical cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Enalapril; Hemolytic Plaque Technique; Immunohistochemistry; Kidney Cortex; Male; Microscopy, Electron; Microscopy, Immunoelectron; Rats; Rats, Inbred WKY; Renin; Tissue Distribution | 1992 |
Reciprocal feedback regulation of kidney angiotensinogen and renin mRNA expressions by angiotensin II.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Feedback; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1992 |
Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Antisense Elements (Genetics); Blood Pressure; DNA; Heart Rate; Humans; Imidazoles; Kidney; Organ Specificity; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Transcription, Genetic | 1992 |
Measurement and identification of prorenin and renin in ovarian follicular fluid from cattle and pig.
Topics: Angiotensin II; Angiotensinogen; Animals; Body Fluids; Cattle; Chromatography, Ion Exchange; Enzyme Activation; Enzyme Precursors; Female; Male; Ovarian Follicle; Renin; Swine; Trypsin | 1992 |
Local renin-angiotensin system in human adrenals and aldosteronomas.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Male; Middle Aged; Renin; Renin-Angiotensin System; RNA, Messenger | 1992 |
Increased angiotensin-(1-7) in hypophysial-portal plasma of conscious sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Chromatography, High Pressure Liquid; Endopeptidases; Gonadotropin-Releasing Hormone; Median Eminence; Peptide Fragments; Peptides; Pituitary Gland; Portal System; Prolyl Oligopeptidases; Radioimmunoassay; Renin; Serine Endopeptidases; Sheep | 1992 |
Identification of serine proteinases with tonin-like activity in the rat submandibular and prostate glands.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kallikreins; Male; Peptidyl-Dipeptidase A; Prostate; Rats; Rats, Inbred Strains; Serine Endopeptidases; Serine Proteinase Inhibitors; Submandibular Gland | 1991 |
Evidence for an intrinsic angiotensin system in the canine pancreas.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Autoradiography; Binding Sites; Dogs; Glucose; Hypertension; Male; Pancreas; RNA, Messenger | 1991 |
Possible role of the vascular renin-angiotensin system in hypertension and vascular hypertrophy.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Hypertension, Renovascular; Hypertrophy; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; RNA, Messenger; Veins | 1992 |
Evidence for a functional tissue renin-angiotensin system in the rat mesenteric vasculature and its involvement in regulating blood pressure.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Electric Stimulation; Isoquinolines; Mesentery; Peptidyl-Dipeptidase A; Quinapril; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Tetrahydroisoquinolines; Vasoconstriction | 1991 |
Local angiotensin formation in hindlimbs of uremic hypertensive and renovascular hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Chromatography, High Pressure Liquid; Hindlimb; Hypertension, Renal; Hypertension, Renovascular; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Uremia | 1991 |
Angiotensin II generation in the rat vena cava: stimulation of local synthesis by beta-adrenoceptor activation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Female; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin-Angiotensin System; Saralasin; Trachea; Tritium; Vena Cava, Superior | 1991 |
Characterization of angiotensin peptides in plasma of anephric man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Chromatography, High Pressure Liquid; Enzyme Precursors; Female; Humans; Kidney; Male; Middle Aged; Nephrectomy; Radioimmunoassay; Renin; Renin-Angiotensin System | 1991 |
Presence of renin, angiotensinogen, angiotensin II in the lamb anterior pituitary gland: immunocytochemical study after cryoultramicrotomy.
Topics: Angiotensin II; Angiotensinogen; Animals; Frozen Sections; Immunohistochemistry; Microscopy, Electron; Models, Biological; Pituitary Gland, Anterior; Prolactin; Renin; Renin-Angiotensin System; Sheep | 1991 |
Studies of the renin-angiotensin system in the wall of rat femoral resistance vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Enzyme Precursors; Femoral Artery; In Vitro Techniques; Indoles; Kallikreins; Male; Muscle, Smooth, Vascular; Norepinephrine; Oligopeptides; Perindopril; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Saralasin; Vascular Resistance | 1991 |
Binding and pharmacologic properties of peptides derived from human and rat angiotensin II (AII) mRNA.
Topics: Adrenergic beta-Agonists; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Base Sequence; Binding, Competitive; Cell Membrane; Humans; Male; Molecular Sequence Data; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; RNA, Messenger; Zona Glomerulosa | 1990 |
Distribution of angiotensinogen immunoreactivity in rat anterior pituitary glands.
Topics: Angiotensin II; Angiotensinogen; Animals; Male; Nephrectomy; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Tissue Distribution | 1991 |
Angiotensin II stimulates angiotensinogen synthesis in hepatocytes by a pertussis toxin-sensitive mechanism.
Topics: Adenylate Cyclase Toxin; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Cyclic AMP; Glucagon; Kinetics; Leucine; Liver; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; RNA, Messenger; Transcription, Genetic; Tritium; Virulence Factors, Bordetella | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Captopril; Enalapril; Gene Expression Regulation; Heart; Hydralazine; Hypertension; Isoquinolines; Kidney; Lisinopril; Male; Quinapril; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrahydroisoquinolines | 1990 |
Rat angiotensinogen is secreted only constitutively when transfected into AtT-20 cells.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Cell Line; Mice; Monensin; Potassium Chloride; Rats; Renin-Angiotensin System; RNA, Messenger; Transfection | 1990 |
Platelet angiotensin II binding and plasma renin concentration, plasma renin substrate and plasma angiotensin II in human pregnancy.
Topics: Angiotensin II; Angiotensinogen; Blood Platelets; Cross-Sectional Studies; Female; Humans; Platelet Count; Pregnancy; Protein Binding; Renin; Time Factors | 1990 |
Involvement of a pertussis toxin-sensitive G protein in the regulation of angiotensinogen production by an angiotensin II analog in HepG2 cells.
Topics: Adenosine Diphosphate Ribose; Angiotensin II; Angiotensinogen; Carcinoma, Hepatocellular; Colforsin; Cyclic AMP; Glucagon; GTP-Binding Proteins; Humans; Liver Neoplasms; Neoplasm Proteins; Pertussis Toxin; Protein Processing, Post-Translational; Second Messenger Systems; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1990 |
Metabolism of tetradecapeptide, angiotensinogen and angiotensin I and II by isolated perfused rat hindlimbs.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Cattle; Hindlimb; Kidney; Nephrectomy; Pepstatins; Perfusion; Rats; Renin; Vasoconstrictor Agents | 1990 |
Effect of angiotensin II on angiotensinogen production in adrenalectomized rats.
Topics: Adrenalectomy; Analysis of Variance; Angiotensin II; Angiotensinogen; Animals; Glucocorticoids; Liver; Male; Rats; Rats, Inbred Strains; Renin; RNA, Messenger | 1990 |
Further studies on the noradrenergic and the renin-angiotensin systems in the brain of the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Central Nervous System; Epinephrine; Male; Norepinephrine; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1990 |
[Regional distribution and function of brain renin angiotensin system].
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Humans; Natriuresis; Pituitary Hormones; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Thirst | 1990 |
Local formation of angiotensin II in the rat aorta: effect of endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Rats, Inbred Strains; Renin | 1990 |
Cardiac angiotensinogen and its local activation in the isolated perfused beating heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Dexamethasone; Female; Heart; In Vitro Techniques; Myocardium; Perfusion; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1990 |
The immunocytochemical localization of angiotensinogen in the rat ovary.
Topics: Angiotensin II; Angiotensinogen; Animals; Epithelium; Estrus; Female; Granulosa Cells; Immunohistochemistry; Ovarian Follicle; Ovary; Rats; Rats, Inbred Strains; Renin | 1990 |
Re-evaluation of the plasma renin-angiotensin system in anephric patients.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Female; Humans; Male; Middle Aged; Nephrectomy; Radioimmunoassay; Renin; Renin-Angiotensin System | 1990 |
Endogenous angiotensin II regulates hepatic angiotensinogen production.
Topics: Angiotensin II; Angiotensinogen; Animals; Enalapril; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger; Sodium | 1990 |
Pharmacological evidence for the existence of a local renin-angiotensin system in porcine interlobar renal arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Enalapril; In Vitro Techniques; Indomethacin; Kallikreins; Kidney; Masoprocol; Muscle Relaxation; Renal Artery; Renin-Angiotensin System; Saralasin; Swine; Tranylcypromine | 1990 |
In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Kidney Tubules, Proximal; Male; Nucleic Acid Hybridization; Rats; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger; Sodium | 1990 |
Regulation of liver angiotensinogen and kidney renin mRNA levels by angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Enalapril; Gene Expression Regulation; Genes; Kidney; Liver; Male; Nucleic Acid Hybridization; Phenylephrine; Rats; Rats, Inbred Strains; Reference Values; Renin; Renin-Angiotensin System; Saralasin; Transcription, Genetic | 1990 |
Renin inhibitors: their use in understanding the role of angiotensin II as a pressor hormone.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dogs; Humans; Male; Oligopeptides; Papio; Renin; Sodium | 1985 |
Contractile effects of tetradecapeptide renin substrate on rat femoral resistance vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aprotinin; Captopril; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vascular Resistance | 1987 |
Angiotensinogen's role in ANG formation, renin release, and renal hemodynamics in isolated perfused kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System | 1989 |
Molecular biology and pathophysiology of the intrarenal renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Gene Expression; Heart Failure; Hypertension, Renal; Kidney; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1989 |
Inhibition of angiotensinogen production by angiotensin II analogues in human hepatoma cell line.
Topics: Angiotensin II; Angiotensinogen; Dactinomycin; Drug Stability; Hematoma; Humans; Iodine Radioisotopes; Receptors, Angiotensin; Tumor Cells, Cultured | 1989 |
Local generation of angiotensin II in the isolated rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1989 |
Effect of locally generated angiotensin II on noradrenergic neuroeffector function in the rat isolated caudal artery.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arteries; Enalapril; Enalaprilat; Female; Male; Neurotransmitter Agents; Oligopeptides; Rats; Rats, Inbred Strains; Tail | 1987 |
Sodium balance effects on renin, angiotensinogen, and atrial natriuretic polypeptide mRNA levels.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Atrial Natriuretic Factor; Kidney; Male; Nucleic Acid Hybridization; Rats; Rats, Inbred Strains; Reference Values; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium, Dietary | 1988 |
Renin-aldosterone axis in ethanol intoxication: effect of A II infusion.
Topics: Adrenal Cortex; Adult; Alcoholic Intoxication; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Heart Rate; Humans; Hydrocortisone; Male; Peptidyl-Dipeptidase A; Renin; Water-Electrolyte Balance | 1985 |
Thirst in Brattleboro rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Crosses, Genetic; Drinking Behavior; Heterozygote; Homozygote; Isoproterenol; Male; Nephrectomy; Rats; Rats, Brattleboro; Rats, Inbred Strains; Rats, Mutant Strains; Saline Solution, Hypertonic; Sodium; Species Specificity; Thirst | 1988 |
Induction of angiotensinogen mRNA in hepatocytes by angiotensin II and glucocorticoids.
Topics: Angiotensin II; Angiotensinogen; Animals; Dexamethasone; Hydrocortisone; In Vitro Techniques; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger | 1988 |
Angiotensin II controls angiotensinogen secretion at a pretranslational level.
Topics: Angiotensin II; Angiotensinogen; Animals; Dactinomycin; Dexamethasone; Gene Expression Regulation; Hydrocortisone; Liver; Male; Rats; Rats, Inbred Strains; RNA, Messenger | 1988 |
Regulation of angiotensinogen production by angiotensin II analogues.
Topics: Angiotensin II; Angiotensinogen; Cell Line; Humans; Liver | 1988 |
Renin-angiotensin system in dogs following chronic bile-duct ligation. Relation to vascular reactivity.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Bile Ducts; Blood Pressure; Dogs; Female; Ligation; Renin; Renin-Angiotensin System | 1988 |
[Correlation of the total activity of blood plasma renin with levels of active and inactive renin, angiotensinogen and angiotensin II under different functional loads in patients with hypertension].
Topics: Adult; Angiotensin II; Angiotensinogen; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Physical Exertion; Propranolol; Prostaglandins E; Renin; Renin-Angiotensin System; Sodium Chloride; Time Factors | 1988 |
Direct release of angiotensins I and II from isolated rat kidney perfused with angiotensinogen-free medium.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renin | 1987 |
Biosynthesis of angiotensinogen and angiotensins by brain cells in primary culture.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Leucine; Molecular Weight; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Induction of angiotensinogen synthesis and secretion by angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Dactinomycin; In Vitro Techniques; Leucine; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Saralasin | 1987 |
Multiple factors contribute to the pathogenesis of hypertension in Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Captopril; Cushing Syndrome; Dinoprostone; Female; Humans; Hydrocortisone; Hypertension; Kallikreins; Male; Middle Aged; Norepinephrine; Prostaglandins E; Renin; Renin-Angiotensin System | 1986 |
Changes in central and peripheral renin-angiotensin system after furosemide injection.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dogs; Furosemide; Male; Renin; Renin-Angiotensin System | 1986 |
Localization of angiotensinogen in multiple cell types of rat brain.
Topics: Angiotensin II; Angiotensinogen; Animals; Astrocytes; Brain; Choroid Plexus; Hypothalamus; Immunoenzyme Techniques; Male; Neurons; Rats; Rats, Inbred WKY | 1987 |
Effect of various components of the renin-angiotensin-aldosterone system on angiotensinogen production in a monolayer culture of adult rat hepatocytes.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Hydrocortisone; Liver; Male; Ouabain; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1987 |
Hormonal and pharmacological alteration of angiotensinogen secretion from rat hepatocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Colchicine; Cycloheximide; Dactinomycin; Immune Sera; In Vitro Techniques; Kinetics; Liver; Male; Puromycin; Radioimmunoassay; Rats; Rats, Inbred Strains; Serum Albumin; Tunicamycin; Vinblastine | 1986 |
Proceedings: Synthesis and secretion of albumin and angiotensinogen by isolated rat liver cells.
Topics: Albumins; Angiotensin II; Angiotensinogen; Animals; In Vitro Techniques; Liver; Rats | 1974 |
Specific inhibition of renin by an angiotensinogen analog: studies in sodium depletion and renin-dependent hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Macaca fascicularis; Male; Oligopeptides; Peptidyl-Dipeptidase A; Renin; Sodium; Teprotide | 1980 |
Drinking and changes in blood pressure in response to precursors, fragments and analogues of angiotensin II in the pigeon Columba livia.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Columbidae; Drinking; Female; Injections; Injections, Intravenous; Male; Peptide Fragments; Teprotide | 1981 |
Neuropeptides in the pineal gland? A critical immunocytochemical study.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Immune Sera; Immunoassay; Male; Microscopy, Electron; Pineal Gland; Rats; Rats, Inbred Strains; Staining and Labeling | 1981 |
Vascular renin-angiotensin: a possible autocrine or paracrine system in control of vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Dogs; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Renin; Renin-Angiotensin System | 1984 |
The afferent glomerular arteriole: immunocytochemical and electrophysiological investigations.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arterioles; Cricetinae; Cricetulus; Electrophysiology; Guinea Pigs; Histocytochemistry; Immunochemistry; Kidney Glomerulus; Mice; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Swine | 1984 |
Interactions between the renin-angiotensin system and the brain.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Dogs; Drinking Behavior; Renin; Sympathetic Nervous System; Vasopressins | 1980 |
Formation of angiotensin II by tonin from partially purified human angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Humans; Kidney; Kinetics; Peptidyl-Dipeptidase A; Rats; Renin; Submandibular Gland | 1981 |
Tonin, an esteroprotease from rat submaxillary glands.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Macromolecular Substances; Male; Peptidyl-Dipeptidase A; Rats; Submandibular Gland; Substrate Specificity | 1981 |
Pressor effect of tonin in anephric animals.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; In Vitro Techniques; Male; Nephrectomy; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Vascular Resistance | 1981 |
Separation of angiotensins and assay of angiotensin-generating enzymes by high-performance liquid chromatography.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Chromatography, High Pressure Liquid; Kinetics; Peptides; Peptidyl-Dipeptidase A; Renin | 1982 |
Immunocytochemistry of the renin-angiotensin system: renin, angiotensinogen, angiotensin I, angiotensin II, and converting enzyme in the kidneys of mice, rats, and tree shrews.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Arterioles; Histocytochemistry; Immunochemistry; Juxtaglomerular Apparatus; Kidney; Male; Mice; Peptidyl-Dipeptidase A; Rats; Renin; Tupaiidae | 1982 |
Brain angiotensinogen: in vitro synthesis and chromatographic characterization.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood-Brain Barrier; Brain; Chromatography, Gel; Concanavalin A; Culture Techniques; Cycloheximide; Cytosol; Endopeptidases; Female; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Vinblastine | 1983 |
Angiotensin-converting enzyme blockade by Captopril changes angiotensin II receptors and angiotensinogen concentrations in the brain of SHR-sp and WKY rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Captopril; Hypothalamus, Anterior; Proline; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Septum Pellucidum | 1982 |
[The renin-angiotensin system of the brain].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Humans; Mice; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Vasopressins | 1983 |
Angiotensin stimulates beta-endorphin release from anterior pituitary gland cell cultures of rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; beta-Endorphin; Captopril; Cells, Cultured; Drug Interactions; Endorphins; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Renin | 1984 |
Renin, renin substrate, angiotensin II, and vasopressin in plasma during treatment with captopril in hypertension and heart failure.
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Angiotensins; Blood Pressure; Captopril; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Time Factors; Vasopressins | 1983 |
Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Male; Muscle Tonus; Muscle, Smooth, Vascular; Oligopeptides; Perfusion; Rats; Rats, Inbred Strains; Renin; Vasoconstrictor Agents | 1984 |
New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon.
Topics: Anesthesia, General; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cathepsin D; Chemical Phenomena; Chemistry; Dogs; Humans; Infusions, Parenteral; Papio; Peptides; Rats; Renin; Sodium | 1983 |
Effects of circulating renin substrate on renal function in isolated perfused rat kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Kidney; Kinetics; Perfusion; Rats; Renin | 1983 |
Angiotensin synthesis in the brain and increased turnover in hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Brain; Hypertension; Nephrectomy; Radioimmunoassay; Rats | 1983 |
Effect of angiotensin II and sodium depletion on angiotensinogen production.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Dactinomycin; Dexamethasone; Estradiol; In Vitro Techniques; Liver; Male; Rats; Renin; Sodium; Vincristine | 1980 |
Separation and quantification of angiotensins and some related peptides by high-performance liquid chromatography.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Chromatography, High Pressure Liquid; Oligopeptides; Peptides; Rats; Renin | 1980 |
Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood-Brain Barrier; Brain Chemistry; Dogs; In Vitro Techniques; Male; Rats; Renin | 1980 |
Stimulation of angiotensinogen production: a dose-related effect of angiotensin II in the conscious dog.
Topics: Adrenal Cortex Hormones; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Liver; Renin | 1980 |
Angiotensin II in human cerebrospinal fluid may be an immunoassay artifact.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Male; Middle Aged; Radioimmunoassay; Renin | 1980 |
Angiotensin II's role in mediating angiotensin I- and tetradecapeptide-induced steroidogenesis by rat glomerulosa cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Captopril; Female; In Vitro Techniques; Kinetics; Rats | 1981 |
Changes in the renin-angiotensin-aldosterone system in normotensive primigravidae in the four days after normal spontaneous delivery.
Topics: Adolescent; Adult; Aldosterone; Angiotensin II; Angiotensinogen; Female; Humans; Parity; Postpartum Period; Pregnancy; Renin; Renin-Angiotensin System; Time Factors | 1982 |
[Hormonal contraception and hypertension].
Topics: Angiotensin II; Angiotensinogen; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Estrogens; Female; Humans; Hypertension; Liver; Renin-Angiotensin System; Sodium; Vasoconstriction | 1982 |
Effects of angiotension II, thyroxine and estrogen on plasma renin substrate concentration and renin substrate production by the liver.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Body Weight; Estrogens; Female; Isoelectric Focusing; Liver; Rats; Rats, Inbred Strains; Thyroxine | 1981 |
Adrenal regulation of regional brain angiotensinogen content.
Topics: Adrenalectomy; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Brain; Cerebrovascular Circulation; Corticosterone; Deoxyglucose; Kinetics; Male; Rats; Tissue Distribution | 1980 |
Blood pressure in terminal renal failure. Fluid spaces and the renin-angiotensin-system.
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Blood Pressure; Body Fluid Compartments; Body Water; Body Weight; Extracellular Space; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renin | 1980 |
Effect of endogenous angiotensin on the efferent glomerular arteriole of rat kidney.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Arteries; Arterioles; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Rats | 1980 |
Modulation of renin-angiotensin and kallikrein gene expression in experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Gene Expression Regulation; Hypertension, Renovascular; Kallikreins; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; RNA; RNA, Messenger | 1994 |
Transient decrease in high blood pressure by in vivo transfer of antisense oligodeoxynucleotides against rat angiotensinogen.
Topics: Analysis of Variance; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cells, Cultured; DNA, Complementary; Genetic Therapy; Hypertension; Liver; Male; Oligonucleotides, Antisense; Parainfluenza Virus 1, Human; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Wistar; RNA; Time Factors; Transfection | 1995 |
Human urinary kallikrein can generate angiotensin II from homologous renin substrates.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kallikreins; Substrate Specificity | 1995 |
Contribution of a 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA: interaction with the 3' untranslated mRNA.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Angiotensin II; Angiotensinogen; Animals; Cell-Free System; Cells, Cultured; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Cytosol; Half-Life; Liver; Macromolecular Substances; Male; Oxidation-Reduction; Phosphorylation; Protein Binding; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Ribosomes; RNA-Binding Proteins; RNA, Messenger | 1995 |
Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats. A study on cause and effect.
Topics: Alleles; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Base Sequence; Female; Genetic Linkage; Hypertension; Male; Molecular Sequence Data; Point Mutation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary | 1995 |
Plasma angiotensin in binephrectomised mice.
Topics: Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Female; Kinetics; Male; Mice; Mice, Inbred BALB C; Nephrectomy; Renin; Renin-Angiotensin System | 1995 |
Angiotensin and asymmetric fetal growth.
Topics: Adult; Angiotensin II; Angiotensinogen; Animals; Birth Weight; Cardiovascular Diseases; Cephalometry; Eclampsia; Embryonic and Fetal Development; Female; Humans; Hypertension; Infant, Newborn; Pregnancy; Pregnancy Complications, Cardiovascular | 1995 |
Frequencies of the angiotensinogen gene and angiotensin I converting enzyme (ACE) gene polymorphisms in African Americans.
Topics: Alleles; Angiotensin I; Angiotensin II; Angiotensinogen; Black People; Gene Frequency; Genotype; Humans; Peptidyl-Dipeptidase A; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Renin-Angiotensin System | 1994 |
Effects of kidney transplantation on the renin-angiotensin systems of the recipients.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Hybridization, Genetic; Hypertension; Kidney; Kidney Transplantation; Male; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1994 |
On the plasticity of the cerebellar renin-angiotensin system: localization of components and effects of mechanical perturbation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cerebellum; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Hybridization; Male; Microscopy, Confocal; Neuroglia; Neuronal Plasticity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 1994 |
Expression of angiotensin-converting enzyme in renovascular hypertensive rat kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Hypertension, Renovascular; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; RNA, Messenger | 1995 |
Identification and antisense inhibition of a renin-angiotensin system in transgenic cardiomyocytes.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Blood; Cell Division; Hypertrophy; Mice; Mice, Transgenic; Molecular Sequence Data; Myocardium; Oligonucleotide Probes; Oligonucleotides, Antisense; Polymerase Chain Reaction; Renin-Angiotensin System; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Angiotensinogen depletion by high renin levels in hypertensive rats: no evidence for tonic stimulation of angiotensinogen by angiotensin II.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Diet; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Renin; Sodium Chloride, Dietary; Tetrazoles | 1995 |
Angiotensinogen dependency of blood pressure in two high-renin hypertensive rat models.
Topics: Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Renin; Sodium, Dietary; Tetrazoles | 1994 |
Beta-adrenergic receptors and angiotensinogen gene expression in mouse hepatoma cells in vitro.
Topics: Angiotensin II; Angiotensinogen; Animals; Cyclic AMP-Dependent Protein Kinases; Dexamethasone; Gene Expression Regulation; Isoproterenol; Liver Neoplasms, Experimental; Mice; Propranolol; Receptors, Adrenergic, beta; Tumor Cells, Cultured | 1995 |
Expression of components of the RAS during prolonged blockade at different levels in primates.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antibodies, Monoclonal; Benzazepines; Blood Pressure; Callithrix; Female; Kidney; Liver; Male; Oligopeptides; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Time Factors; Valine; Valsartan | 1994 |
Effects of alteration in fluid balance on angiotensinogen gene expression in the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Brain Chemistry; Gene Expression; In Situ Hybridization; Liver; Male; Nucleic Acids; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Regression Analysis; Water-Electrolyte Balance | 1994 |
Vasoconstrictor responses to components of the renin-angiotensin system in cyclosporin-induced hypertension in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cyclosporine; Female; Hypertension; In Vitro Techniques; Mesenteric Arteries; Rats; Rats, Wistar; Renin-Angiotensin System; Sensitivity and Specificity; Vascular Resistance; Vasoconstriction | 1994 |
Effects of converting enzyme inhibitors on angiotensin and bradykinin peptides.
Topics: Adipose Tissue, Brown; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aorta; Bradykinin; Indoles; Kidney; Lisinopril; Lung; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Sprague-Dawley; Renin | 1994 |
Cardiac renin is kidney-derived.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Myocardium; Nephrectomy; Renin; Swine; Tissue Distribution | 1993 |
Changes in plasma renin and angiotensin run in parallel after nephrectomy.
Topics: Aged; Angiotensin II; Angiotensinogen; Captopril; Carcinoma, Renal Cell; Enzyme Precursors; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Pyelonephritis; Renal Dialysis; Renin; Renin-Angiotensin System | 1993 |
Angiotensin II is the mediator of the increase in hepatic angiotensinogen synthesis after bilateral nephrectomy.
Topics: Adrenalectomy; Angiotensin II; Angiotensinogen; Animals; Atenolol; Biphenyl Compounds; Imidazoles; Kidney; Liver; Losartan; Male; Nephrectomy; Osmolar Concentration; Postoperative Period; Rats; Rats, Wistar; Renin; Tetrazoles; Time Factors | 1993 |
Angiotensin II stimulates the synthesis of angiotensinogen in hepatocytes by inhibiting adenylylcyclase activity and stabilizing angiotensinogen mRNA.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Angiotensinogen; Animals; Cyclic AMP; Glucagon; Liver; Male; Membrane Proteins; Pertussis Toxin; Rats; Rats, Sprague-Dawley; RNA Processing, Post-Transcriptional; RNA, Messenger; Signal Transduction; Transcription, Genetic; Virulence Factors, Bordetella | 1993 |
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Cytoplasmic Granules; Endothelins; Gene Expression Regulation; Genes, fos; Hypertrophy; In Vitro Techniques; Mechanoreceptors; Myocardium; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger; Stress, Mechanical | 1993 |
Mechanism by which angiotensin II stabilizes messenger RNA for angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Nucleus; Cell-Free System; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Dichlororibofuranosylbenzimidazole; Guanfacine; Kinetics; Liver; Male; Phosphates; Phosphoproteins; Phosphorylation; Polyribosomes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thionucleotides; Time Factors; Uridine | 1994 |
PCR localization of angiotensin II receptor and angiotensinogen mRNAs in rat kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Kidney; Male; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger | 1993 |
Regulation of intrarenal and circulating renin-angiotensin systems in severe heart failure in the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Disease Models, Animal; Heart Failure; Kidney; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1993 |
Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Genes, fos; Hyperplasia; Myocardium; Rats; Receptors, Angiotensin; Transforming Growth Factor beta | 1993 |
Angiotensinogen mRNA and pressor reactions to angiotensin in brain stem areas of spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood Vessels; Brain Stem; Female; Male; Peripheral Nerves; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Tissue Distribution | 1993 |
Arteriolar constriction and local renin-angiotensin system in rat microcirculation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arterioles; In Vitro Techniques; Male; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nephrectomy; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction | 1993 |
Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Nucleus; Dose-Response Relationship, Drug; Liver; Nucleic Acid Hybridization; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; RNA, Messenger; Transcription, Genetic | 1993 |
Nephrectomy, converting enzyme inhibition, and angiotensin peptides.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Chromatography, High Pressure Liquid; Male; Nephrectomy; Peptides; Peptidyl-Dipeptidase A; Radioimmunoassay; Ramipril; Rats; Rats, Sprague-Dawley; Reference Values; Renin | 1993 |
Role of tissue renin angiotensin system in two-kidney, one-clip hypertensive rats.
Topics: Actins; Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Brain; Cerebellum; Gene Expression; Hypertension, Renovascular; Hypothalamus; Kidney; Male; Medulla Oblongata; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; RNA, Messenger | 1993 |
Regulation of vascular angiotensin release.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aorta; Base Sequence; Biphenyl Compounds; Dexamethasone; Ethinyl Estradiol; Hindlimb; Imidazoles; Losartan; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Muscles; Nephrectomy; Oligodeoxyribonucleotides; Perfusion; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Triiodothyronine | 1993 |
Angiotensin II and dexamethasone regulate angiotensinogen mRNA by different mechanisms.
Topics: Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Dexamethasone; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1993 |
Dependence of angiotensin production in transgenic mice carrying either the human renin or human angiotensinogen genes on species-specific kinetics of the renin-angiotensin system.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Hypertension; Kidney; Kinetics; Liver; Mice; Mice, Transgenic; Molecular Sequence Data; Renin; Renin-Angiotensin System; Species Specificity | 1993 |
Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Captopril; Hindlimb; In Vitro Techniques; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1993 |
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Dipeptides; Humans; Imidazoles; Losartan; Male; Mice; Mice, Transgenic; Morpholines; Recombinant Proteins; Renin; Renin-Angiotensin System; Tetrazoles | 1993 |
Activation of angiotensin-generating systems in the developing rat kidney.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Female; Gene Expression; Humans; Kidney; Male; Peptidyl-Dipeptidase A; Pregnancy; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1996 |
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Indoles; Male; Peptide Fragments; Perindopril; Radioimmunoassay; Rats; Rats, Inbred SHR; Renin; Tissue Distribution | 1995 |
Inhibition of hypertension by peripheral administration of antisense oligodeoxynucleotides.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Data Interpretation, Statistical; Drug Carriers; Hypertension; In Vitro Techniques; Liposomes; Liver; Male; Oligonucleotides, Antisense; Protein Biosynthesis; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic | 1996 |
Gene targeting in mice reveals a requirement for angiotensin in the development and maintenance of kidney morphology and growth factor regulation.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Gene Expression; Growth Substances; Homeostasis; Kidney; Kidney Cortex; Kidney Glomerulus; Kidney Medulla; Mice; Mice, Knockout; Mice, Mutant Strains; Organ Size; Platelet-Derived Growth Factor; Restriction Mapping; RNA, Messenger; Transforming Growth Factor beta | 1995 |
Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity.
Topics: Adolescent; Adult; Angiotensin II; Angiotensinogen; Base Sequence; Blood Pressure; Body Mass Index; Female; Genotype; Homozygote; Humans; Hypertension; Infusions, Intravenous; Kidney; Male; Middle Aged; Molecular Sequence Data; Obesity; Oligonucleotide Probes; Pedigree; Renal Artery; Renal Plasma Flow; Vascular Resistance; Vasoconstrictor Agents | 1996 |
Isolation of a renin-like enzyme from the leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; Binding Sites; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leeches; Molecular Sequence Data; Molecular Weight; Peptides; Rats; Renin; Substrate Specificity; Swine; Temperature | 1995 |
Tissue-specific regulation of type 1 angiotensin II receptor mRNA levels in the rat.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Diet, Sodium-Restricted; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; RNA, Messenger; Tissue Distribution | 1996 |
Quadrupole ion trap mass spectrometry.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Aspartic Acid; Electrophoresis, Capillary; Enkephalins; Glutamic Acid; Gramicidin; Growth Hormone-Releasing Hormone; Humans; Lactalbumin; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Myocardium; Myoglobin; Peptides; Poly A; Recombinant Proteins; Sequence Analysis | 1996 |
Angiotensinogen gene activation by angiotensin II is mediated by the rel A (nuclear factor-kappaB p65) transcription factor: one mechanism for the renin angiotensin system positive feedback loop in hepatocytes.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Carcinoma, Hepatocellular; Enhancer Elements, Genetic; Feedback; Gene Expression Regulation; Humans; Liver; Liver Neoplasms; Macromolecular Substances; Models, Biological; NF-kappa B; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Renin-Angiotensin System; Signal Transduction; Transcription Factor RelA; Transcription Factor RelB; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Receptor-mediated intrarenal angiotensin II augmentation in angiotensin II-infused rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Hypertension; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Tetrazoles | 1996 |
The renin-angiotensin system in the rabbit eye.
Topics: Angiotensin II; Angiotensinogen; Animals; Eye; Female; Male; Ocular Hypertension; Peptidyl-Dipeptidase A; Rabbits; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Vitreoretinopathy, Proliferative | 1996 |
Hypertension induced in pregnant mice by placental renin and maternal angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Kidney Glomerulus; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
Effect of angiotensinogen on blood pressure regulation in normotensive rats: application of a loss of function approach.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Blood Pressure; Blotting, Northern; Gene Transfer Techniques; Infusions, Intravenous; Liver; Male; Microscopy, Fluorescence; Molecular Sequence Data; Oligonucleotides, Antisense; Portal Vein; Rats; Rats, Wistar; RNA, Messenger | 1995 |
Valvular interstitial cells express angiotensinogen and cathepsin D, and generate angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; Cathepsin D; Cells, Cultured; Dexamethasone; Enzyme Inhibitors; Gene Expression; Haloperidol; Heart Valves; Lisinopril; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1996 |
Expression of angiotensinogen mRNA and localization of angiotensin II and renin in peripheral adrenergic neurons in primary culture.
Topics: Adrenergic Fibers; Angiotensin II; Angiotensinogen; Animals; Immunohistochemistry; In Situ Hybridization; Neurons; Renin; RNA, Messenger; Swine | 1996 |
Mouse model for pregnancy problem?
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Crosses, Genetic; Disease Models, Animal; Female; Humans; Hypertension; Male; Mice; Mice, Transgenic; Placenta; Pregnancy; Pregnancy Complications, Cardiovascular; Renin | 1996 |
The role of intermediate phenotypes in essential hypertension: non-modulation as a model.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Blood Flow Velocity; Genotype; Humans; Hypertension; Kidney; Middle Aged; Phenotype; Renin; Sodium, Dietary | 1996 |
Angiotensin-independent mechanism for aldosterone synthesis during chronic extracellular fluid volume depletion.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Cytochrome P-450 CYP11B2; Diet, Sodium-Restricted; Extracellular Space; Genetic Engineering; Glyceraldehyde-3-Phosphate Dehydrogenases; Hypotension; Mice; Mice, Mutant Strains; Mixed Function Oxygenases; Potassium; Renin-Angiotensin System; RNA, Messenger; Sequence Deletion; Signal Transduction; Sodium; Zona Glomerulosa | 1997 |
The renin-angiotensin system in patients with repeated anaphylactic reactions during hymenoptera venom hyposensitization and sting challenge.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arthropod Venoms; Child; Desensitization, Immunologic; Female; Humans; Hymenoptera; Immunotherapy; Insect Bites and Stings; Male; Middle Aged; Radioallergosorbent Test; Renin; Renin-Angiotensin System | 1997 |
Differences in cultured cardiac fibroblast populations isolated from SHR and WKY rats.
Topics: Actins; Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Cells, Cultured; Fibroblasts; Heart Ventricles; Immunohistochemistry; Myocardium; Plasmids; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger | 1995 |
Age, gender, and non-modulation. A sexual dimorphism in essential hypertension.
Topics: Adolescent; Adult; Age Factors; Aged; Aldosterone; Angiotensin II; Angiotensinogen; Data Interpretation, Statistical; Female; Genotype; Humans; Hypertension; Infusions, Parenteral; Male; Menopause; Middle Aged; Phenotype; Postmenopause; Premenopause; Sex Factors | 1997 |
Angiotensinogen messenger RNA stabilization by angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Cell Separation; Drug Stability; Genome; Liver; Male; Molecular Sequence Data; Molecular Weight; Mutation; Polyribosomes; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; RNA, Messenger | 1996 |
Characterization of renin activity in brown adipose tissue.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Gene Expression; Hydrogen-Ion Concentration; Immunologic Techniques; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
[Does a genetic predisposition for infarction expansion exist? Evaluation of genetic polymorphisms of the renin-angiotensin system].
Topics: Aged; Alleles; Angiotensin II; Angiotensinogen; Causality; Confidence Intervals; Echocardiography; Female; Genes; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Angiotensin; Renin-Angiotensin System | 1997 |
Stretch-induced MAP kinase activation in cardiomyocytes of angiotensinogen-deficient mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Gene Targeting; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Peptides, Cyclic; Renin-Angiotensin System; Tetrazoles | 1997 |
Cultured myofibroblasts generate angiotensin peptides de novo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; beta 2-Microglobulin; Blotting, Western; Cathepsin D; Cells, Cultured; Fluorescent Antibody Technique, Indirect; Gene Expression; Heart Ventricles; Lisinopril; Male; Myocardium; Peptide Biosynthesis; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
p53 Induces myocyte apoptosis via the activation of the renin-angiotensin system.
Topics: Adenoviridae; Angiotensin II; Angiotensinogen; Animals; Apoptosis; bcl-2-Associated X Protein; Gene Expression; Gene Transfer Techniques; Heart Ventricles; Humans; Molecular Sequence Data; Muscle Fibers, Skeletal; Myocardium; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; RNA, Messenger; Tumor Suppressor Protein p53 | 1997 |
Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Bradykinin; Cardiovascular System; DNA, Complementary; Electrophoresis, Agar Gel; Female; Gene Targeting; Heart Rate; Injections, Intravenous; Male; Mice; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Phenotype; Receptors, Angiotensin; RNA; RNA, Messenger | 1997 |
Changes in the maternal and fetal renin-angiotensin systems in response to angiotensin II type 1 receptor blockade and angiotensin-converting enzyme inhibition in pregnant sheep during late gestation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Benzofurans; Captopril; Female; Fetus; Gestational Age; Pregnancy; Pregnancy, Animal; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sheep | 1997 |
Tissue-specific changes in angiotensin II receptors in streptozotocin-diabetic rats.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Diabetes Mellitus, Experimental; Insulin; Kidney; Liver; Male; Myocardium; Rats; Rats, Wistar; Receptors, Angiotensin; Renin | 1997 |
Anti-apoptotic action of angiotensin fragments to neuronal cells from angiotensinogen knock-out mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis; Cell Count; Hippocampus; Mice; Mice, Knockout; Neurotransmitter Agents | 1997 |
Potent in vivo inhibitors of rat renin: analogues of human and rat angiotensinogen sequences containing different classes of pseudodipeptides at the scissile site.
Topics: Amino Acids; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dipeptides; Humans; Kidney; Peptide Fragments; Protease Inhibitors; Rats; Renin | 1997 |
Regulation by glucocorticoids of angiotensinogen gene expression and secretion in adipose cells.
Topics: Adipocytes; Angiotensin II; Angiotensinogen; Animals; Cell Differentiation; Cell Line; Cells, Cultured; Colforsin; Dexamethasone; Estradiol; Gene Expression Regulation; Glucocorticoids; Growth Hormone; Hormone Antagonists; Male; Mice; Mifepristone; Rats; Rats, Wistar; RNA, Messenger; Testis | 1997 |
Increased cardiac angiotensin II receptors in angiotensinogen-deficient mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Hypotension; Mice; Mice, Knockout; Myocardium; Organ Culture Techniques; Radioligand Assay; Receptors, Angiotensin | 1998 |
Role of AT1 angiotensin II receptors in renal ischemic injury.
Topics: Angiotensin II; Angiotensinogen; Animals; Creatinine; Ischemia; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Proximal; Losartan; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Reperfusion; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1998 |
Murine double nullizygotes of the angiotensin type 1A and 1B receptor genes duplicate severe abnormal phenotypes of angiotensinogen nullizygotes.
Topics: Adrenal Glands; Anesthetics; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Blood Pressure; Imidazoles; Infusions, Intravenous; Kidney; Losartan; Mice; Mice, Knockout; Myocardium; Phenotype; Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Saralasin; Staining and Labeling; Tetrazoles; Thiopental; Zygote | 1998 |
Genetic deficiency of angiotensinogen produces an impaired urine concentrating ability in mice.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Creatinine; Kidney; Kidney Concentrating Ability; Mice; Mice, Knockout; Potassium; Sodium; Vasopressins; Water Deprivation | 1998 |
Angiotensinogen gene null-mutant mice lack homeostatic regulation of glomerular filtration and tubular reabsorption.
Topics: Actins; Angiotensin II; Angiotensinogen; Animals; Atrial Natriuretic Factor; Blood Pressure; Female; Glomerular Filtration Rate; Homeostasis; In Situ Hybridization; Kidney Concentrating Ability; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Knockout; Proliferating Cell Nuclear Antigen; RNA, Messenger; Transforming Growth Factor beta | 1998 |
Increased mRNA expression of cardiac renin-angiotensin system and collagen synthesis in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Collagen; Hypertension; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger | 1998 |
Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: a cellular signal for hypertrophy in cardiac muscle.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Cells, Cultured; DNA-Binding Proteins; Gene Expression Regulation; Heart; Male; Milk Proteins; Promoter Regions, Genetic; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; STAT6 Transcription Factor; Trans-Activators; Transcriptional Activation | 1998 |
Reduction of cold-induced hypertension by antisense oligodeoxynucleotides to angiotensinogen mRNA and AT1-receptor mRNA in brain and blood.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antisense Elements (Genetics); Aorta; Autoradiography; Blood; Blood Pressure; Brain; Cold Temperature; Drinking; Hypertension; Kidney; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 1998 |
Blood pressure-independent cardiac hypertrophy induced by locally activated renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Blotting, Southern; Blotting, Western; Cardiomegaly; DNA; Heart Rate; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Polymerase Chain Reaction; Rabbits; Rats; Renin; Renin-Angiotensin System; RNA; Transgenes | 1998 |
Polymorphisms at the angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) loci and normal blood pressure.
Topics: Analysis of Variance; Angiotensin II; Angiotensinogen; Base Sequence; Blood Pressure; DNA Primers; Heterozygote; Homozygote; Humans; Polymorphism, Genetic; Receptors, Angiotensin | 1998 |
Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Female; Iodine Radioisotopes; Myocardium; Renin; Swine | 1998 |
Activation of angiotensinogen gene in cardiac myocytes by angiotensin II and mechanical stretch.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; beta-Galactosidase; Biphenyl Compounds; Cells, Cultured; Chloramphenicol O-Acetyltransferase; Cycloheximide; Dactinomycin; Gene Expression Regulation; Heart; Heart Ventricles; Imidazoles; Liver; Lung; Myocardium; Promoter Regions, Genetic; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Fusion Proteins; RNA, Messenger; RNA, Ribosomal, 18S; Stress, Mechanical; Tetrazoles; Transcription, Genetic; Transfection | 1998 |
Pouch tissue and angiotensin peptide generation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Aspartic Acid Endopeptidases; Cathepsin D; Collagen; Gene Expression; Imidazoles; Lisinopril; Losartan; Myocardium; Peptide Biosynthesis; Peptides; Peptidyl-Dipeptidase A; Pyridines; Rats; Renin; Transforming Growth Factor beta | 1998 |
Impaired blood-brain barrier function in angiotensinogen-deficient mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Astrocytes; Blood-Brain Barrier; Brain Injuries; Cell Adhesion; Cells, Cultured; Glial Fibrillary Acidic Protein; Mice; Mice, Knockout | 1998 |
Insulin-mediated growth in aortic smooth muscle and the vascular renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Aorta; Captopril; Cell Division; Cells, Cultured; Insulin; Losartan; Male; Muscle Development; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Renin-Angiotensin System; Serine Proteinase Inhibitors; Thymidine; Vasoconstrictor Agents | 1998 |
Increased expression of glomerular AT1 receptors in rats with myocardial infarction.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Down-Regulation; Gene Expression Regulation; Kidney Cortex; Kidney Glomerulus; Kinetics; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Up-Regulation | 1998 |
Effects of neutral endopeptidase inhibition and combined angiotensin converting enzyme and neutral endopeptidase inhibition on angiotensin and bradykinin peptides in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Body Weight; Bradykinin; Cyclic GMP; Diuresis; Electrolytes; Heart; Male; Neprilysin; Organ Size; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renin | 1998 |
The renin-angiotensin system in hybrid NG108-15 cells. Renin gene is from mouse neuroblastoma, angiotensinogen and angiotensin-converting enzyme genes are of rat glioma origin.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cell Line; DNA Primers; Glioma; Hybrid Cells; Lisinopril; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Phosphorylation; Polymerase Chain Reaction; Rats; Renin-Angiotensin System; RNA, Messenger | 1998 |
Human adipose tissue expresses angiotensinogen and enzymes required for its conversion to angiotensin II.
Topics: Adipose Tissue; Adult; Angiotensin II; Angiotensinogen; Cathepsin D; Cathepsin G; Cathepsins; Female; Humans; Middle Aged; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases | 1998 |
The renin-angiotensin system in the vessel wall.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aorta; Blood Vessels; Coronary Vessels; Hindlimb; Humans; Hypertension, Renovascular; In Vitro Techniques; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Swine | 1998 |
Expression and localization of the renin-angiotensin system in the rat pancreas.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Western; Endothelium, Vascular; Epithelium; Gene Expression; Immunohistochemistry; Pancreas; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II.
Topics: Adrenal Glands; Angiotensin II; Angiotensinogen; Animals; Atrophy; Blood Pressure; Crosses, Genetic; Epinephrine; Female; Growth; Homozygote; Humans; Kidney; Kidney Medulla; Male; Mice; Mice, Knockout; Phenotype; Protein Isoforms; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Restriction Mapping; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1998 |
Effect of chronic captopril treatment on circulating and tissue renin-angiotensin system in SHR rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Hypertension; Hypertrophy, Left Ventricular; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; RNA, Messenger | 1996 |
Tissue-localized angiotensin II enhances cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Mice, Transgenic; Renin | 1998 |
Effects of human prorenin in rats transgenic for human angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Chemotherapy, Cancer, Regional Perfusion; Enzyme Precursors; Female; Humans; Infusions, Intravenous; Kinetics; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renin | 1999 |
Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback.
Topics: Angiotensin II; Angiotensinogen; Animals; Autocrine Communication; Cell Line, Transformed; Defective Viruses; DNA, Viral; Feedback; Kidney Tubules, Proximal; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Simian virus 40 | 1999 |
Effects of mineralocorticoid receptor gene disruption on the components of the renin-angiotensin system in 8-day-old mice.
Topics: Adrenal Glands; Angiotensin II; Angiotensinogen; Animals; Blotting, Northern; Female; Gene Expression Regulation; Heart; Immunohistochemistry; In Situ Hybridization; Kidney; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sodium | 1999 |
Insulin-like growth factor-1 induces Mdm2 and down-regulates p53, attenuating the myocyte renin-angiotensin system and stretch-mediated apoptosis.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis; Cells, Cultured; DNA Primers; DNA-Binding Proteins; Down-Regulation; Heart Ventricles; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Myocardium; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stress, Mechanical; Tumor Suppressor Protein p53 | 1999 |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Humans; Hydralazine; Hypertension; Kidney Diseases; Lisinopril; Mice; Mice, Inbred C57BL; Renin; Renin-Angiotensin System; Survival Rate | 1999 |
Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arginine Vasopressin; Blood Pressure; Brain; Cerebral Ventricles; Diabetes Insipidus; Electrolytes; Exons; Hypertension; Hypotension; Injections, Intraventricular; Organ Specificity; Rats; Renin; RNA, Antisense; RNA, Messenger; Transcription, Genetic | 1999 |
The renal lesions that develop in neonatal mice during angiotensin inhibition mimic obstructive nephropathy.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Apoptosis; Cell Division; Disease Models, Animal; Epidermal Growth Factor; Gene Expression Regulation, Developmental; In Situ Hybridization; In Situ Nick-End Labeling; Insulin-Like Growth Factor I; Kidney Diseases; Kidney Medulla; Kidney Pelvis; Macrophages; Mice; Mice, Knockout; Muscle, Smooth; Peptidyl-Dipeptidase A; Platelet-Derived Growth Factor; Pressure; RNA, Messenger; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 1999 |
Angiotensin II induces apoptosis in human and rat alveolar epithelial cells.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Apoptosis; Cells, Cultured; Epithelial Cells; Humans; Lisinopril; Male; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saralasin; Tumor Cells, Cultured | 1999 |
Type 2 bradykinin-receptor antagonism does not modify kinin or angiotensin peptide levels.
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Autoradiography; Bradykinin; Bradykinin Receptor Antagonists; Data Interpretation, Statistical; Feedback; Fluorometry; In Vitro Techniques; Kidney; Kinins; Lung; Male; Myocardium; Neprilysin; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Renin; Time Factors | 1999 |
Evidence for a local renin angiotensin system in primary cultured human preadipocytes.
Topics: Adipocytes; Adult; Angiotensin II; Angiotensinogen; Blotting, Western; Carbohydrate Epimerases; Carrier Proteins; Cells, Cultured; Enzyme Precursors; Female; Gene Expression; Humans; Male; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1999 |
Mechanical stretch and angiotensin II differentially upregulate the renin-angiotensin system in cardiac myocytes In vitro.
Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Antisense Elements (Genetics); Blotting, Southern; Cells, Cultured; Fibroblasts; Gene Expression; Heart Ventricles; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Losartan; Muscle Fibers, Skeletal; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Mechanical | 1999 |
Genotype-phenotype relationships for the renin-angiotensin-aldosterone system in a normal population.
Topics: Adult; Angiotensin II; Angiotensinogen; Binding Sites; Blood Platelets; Blood Pressure; Cytochrome P-450 CYP11B2; Female; Genotype; Humans; Male; Peptidyl-Dipeptidase A; Phenotype; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System | 1999 |
Effect of renal perfusion pressure on renal function, renin release and renin and angiotensinogen gene expression in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Feedback; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; In Situ Hybridization; Inulin; Kidney; Losartan; Rats; Rats, Wistar; Renal Circulation; Renin | 1999 |
Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Captopril; Cells, Cultured; Culture Media, Serum-Free; Enzyme Precursors; Fibroblasts; Hypertrophy; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin; Stress, Mechanical | 1999 |
[Genetic analysis of candidate gene polymorphisms in elderly hypertension].
Topics: Aged; Angiotensin II; Angiotensinogen; Apolipoproteins; Case-Control Studies; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Risk Factors | 1999 |
Modulation of the intrahepatic renin-angiotensin system after stimulation of the gastric sodium monitor in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Gastric Mucosa; Liver; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Sodium; Time Factors | 2000 |
Human lung myofibroblast-derived inducers of alveolar epithelial apoptosis identified as angiotensin peptides.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Antibodies; Apoptosis; Blotting, Western; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibrosis; Flow Cytometry; Gene Expression; Humans; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Saralasin | 1999 |
Fas-induced apoptosis of alveolar epithelial cells requires ANG II generation and receptor interaction.
Topics: Adenocarcinoma; Amino Acid Chloromethyl Ketones; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antibodies; Antisense Elements (Genetics); Apoptosis; Cysteine Proteinase Inhibitors; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; fas Receptor; Fibrosis; Gene Expression; Humans; Lisinopril; Lung Neoplasms; Male; Membrane Glycoproteins; Neutralization Tests; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Transfection; Tumor Cells, Cultured | 1999 |
Developmental stage-specific involvement of angiotensin in murine nephrogenesis.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Apoptosis; In Situ Nick-End Labeling; Kidney; Mice; Mice, Knockout; Microscopy, Electron; Time Factors | 1999 |
Angiotensin II induces nuclear factor (NF)-kappaB1 isoforms to bind the angiotensinogen gene acute-phase response element: a stimulus-specific pathway for NF-kappaB activation.
Topics: Angiotensin II; Angiotensinogen; Base Sequence; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Kinetics; Ligases; Models, Biological; Molecular Sequence Data; NF-kappa B; Protein Binding; Protein Isoforms; Protein Kinase C; Response Elements; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Diseases; Humans; Hypertension, Renal; Interleukin-6; Kidney; Male; Monocytes; Myocardium; Neutrophils; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Binding; Rats; Renin | 2000 |
The brain renin-angiotensin system modulates angiotensin II-induced hypertension and cardiac hypertrophy.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Blood Pressure; Brain Chemistry; Cardiomegaly; Collagen; Gene Expression; Heart Ventricles; Hypertension, Renal; Male; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 2000 |
Renin-angiotensin system genetic polymorphisms and salt sensitivity in essential hypertension.
Topics: Adult; Alleles; Angiotensin II; Angiotensinogen; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Gene Deletion; Gene Frequency; Genotype; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2000 |
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Diuresis; Glomerular Filtration Rate; Humans; Hydralazine; Hydrochlorothiazide; Ki-67 Antigen; Kidney; Male; Myocardium; Natriuresis; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin; Reserpine; Sodium; Transgenes | 2000 |
Chronic antisense therapy for angiotensinogen on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Gene Expression; Genetic Therapy; Injections, Intravenous; Liver; Male; Myocardium; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Ventricular Remodeling | 1999 |
Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats.
Topics: Algorithms; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies, Blocking; Blood Pressure; Blotting, Western; Carrier Proteins; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Male; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Vaccines; Vasoconstrictor Agents | 2000 |
Effect of maximal reduction of angiotensin in renal fibrosis: bad news-good news from a pediatric mouse.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Fibrosis; Kidney Diseases; Mice; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Transforming Growth Factor beta; Ureteral Obstruction | 2000 |
The renin angiotensin system and hymenoptera venom anaphylaxis.
Topics: Adolescent; Adult; Aged; Aldosterone; Anaphylaxis; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Bee Venoms; Child; Desensitization, Immunologic; Female; Homeostasis; Humans; Hypotension; Male; Middle Aged; Renin; Renin-Angiotensin System; Severity of Illness Index; Wasp Venoms | 1993 |
Angiotensinogen and AT(1) antisense inhibition of osteopontin translation in rat proximal tubular cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Hydronephrosis; In Situ Hybridization; Kidney Tubules, Proximal; Male; Oligonucleotides, Antisense; Osteopontin; Peptidyl-Dipeptidase A; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Sialoglycoproteins; Ureteral Obstruction | 2000 |
Cross talk between adipocytes and their precursors: relationships with adipose tissue development and blood pressure.
Topics: Adipocytes; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Epoprostenol; Humans; Mice; Signal Transduction; Up-Regulation | 1999 |
Evidence for an intrarenal renin-angiotensin system in the rainbow trout, Oncorhynchus mykiss.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blotting, Northern; Captopril; DNA, Complementary; Female; Gene Expression; Glomerular Filtration Rate; In Vitro Techniques; Kidney; Male; Oncorhynchus mykiss; Perfusion; Pressure; Renal Circulation; Renin-Angiotensin System; RNA, Messenger; Urine | 2000 |
Reduction of plasma angiotensin II to normal levels by antisense oligodeoxynucleotides against liver angiotensinogen cannot completely attenuate vascular remodeling in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Blood Pressure; Blood Vessels; Collagen; Hypertension; Liver; Oligonucleotides, Antisense; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; RNA, Messenger; Tunica Media | 2000 |
Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Bosentan; Cardiomegaly; Fibronectins; Heart; Humans; Hydralazine; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Kidney; Macrophages; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides; Thromboplastin; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1 | 2000 |
Inhibition of p53 function prevents renin-angiotensin system activation and stretch-mediated myocyte apoptosis.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cells, Cultured; DNA Probes; Genes, p53; Heart Ventricles; In Situ Nick-End Labeling; Microscopy, Confocal; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Stress, Mechanical; Up-Regulation | 2000 |
Increased gene expression of components of the renin-angiotensin system in glomeruli of genetically hypertensive rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blotting, Northern; Fibronectins; Gene Expression; Glomerulosclerosis, Focal Segmental; Hydralazine; Hypertension, Renal; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Ribonucleases; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2000 |
Angiotensin II-induced cardiac hypertrophy is associated with different mitogen-activated protein kinase activation in normotensive and hypertensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Cells, Cultured; Enzyme Activation; Female; Hypertension; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Myosin Heavy Chains; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Renin; Stress, Mechanical; Transgenes; Vasoconstrictor Agents | 2000 |
Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cell Division; Cholesterol; Creatinine; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Kidney; Kidney Failure, Chronic; Leukocytes; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Organ Size; Phosphorylation; Plasminogen Activators; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Thromboplastin; Transcription Factor AP-1; Urea; Vascular Cell Adhesion Molecule-1; Vasoconstrictor Agents | 2000 |
Apoptosis of lung epithelial cells in response to TNF-alpha requires angiotensin II generation de novo.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression; Humans; Lisinopril; Lung; Protein Processing, Post-Translational; Receptors, Angiotensin; RNA, Messenger; Saralasin; Tumor Necrosis Factor-alpha | 2000 |
Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Captopril; Collagen; Coronary Vessels; Hydralazine; Hypertension; Kidney Glomerulus; Male; Myocardium; Orchiectomy; Rats; Rats, Inbred SHR; Testosterone | 2000 |
Genetic evidence that lethality in angiotensinogen-deficient mice is due to loss of systemic but not renal angiotensinogen.
Topics: Alleles; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Blotting, Southern; Crosses, Genetic; Female; Genetic Complementation Test; Genotype; Humans; Kidney; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Phenotype; Renin; Sex Factors; Time Factors | 2001 |
Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction.
Topics: Adult; Age of Onset; Angiotensin II; Angiotensinogen; Apolipoproteins E; Cholesterol; Genotype; Humans; Lipoproteins, HDL; Male; Middle Aged; Myocardial Infarction; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Risk Factors; Triglycerides | 2000 |
Chronic hypoxia induced down-regulation of angiotensinogen expression in rat epididymis.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Western; Chronic Disease; Down-Regulation; Epididymis; Hypoxia; In Situ Hybridization; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Early diabetes mellitus stimulates proximal tubule renin mRNA expression in the rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Gene Expression; Hypertrophy; Hypoglycemic Agents; Insulin; Kidney Tubules, Proximal; Losartan; Male; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger | 2000 |
Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Astrocytes; Autoradiography; Benzimidazoles; Biphenyl Compounds; Blood-Brain Barrier; Brain Chemistry; Diabetes Insipidus; Drinking; Imidazoles; Injections, Intraventricular; Iodine Radioisotopes; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Antisense; Salts; Subfornical Organ; Tetrazoles; Vasoconstrictor Agents | 2001 |
Upregulation of immunoreactive angiotensin II release and angiotensinogen mRNA expression by high-frequency preganglionic stimulation at the canine cardiac sympathetic ganglia.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Atropine; Blotting, Northern; Captopril; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Ganglia, Sympathetic; Gene Expression Regulation; Heart; Heart Rate; Pentolinium Tartrate; Pyridines; RNA, Messenger; Stellate Ganglion; Tetrazoles; Tissue Distribution; Up-Regulation | 2001 |
Effect of oral contraceptives on the renin angiotensin system and renal function.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Blood Pressure; Contraceptives, Oral; Female; Glomerular Filtration Rate; Humans; Inulin; Kidney; Losartan; p-Aminohippuric Acid; Premenopause; Renal Circulation; Renin; Renin-Angiotensin System; Vascular Resistance | 2001 |
Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Base Sequence; Blotting, Western; DNA Primers; Gene Expression; Hypertension; Immunohistochemistry; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 2001 |
Regulation of angiotensinogen gene expression and protein in neonatal rat cardiac fibroblasts by glucocorticoid and beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Culture Techniques; Dexamethasone; Fibroblasts; Gene Expression; Glucocorticoids; Isoproterenol; Myocardium; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2000 |
Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Functional Laterality; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles | 2001 |
Influence of sodium intake on the reliability of active renin as a measure of the renin-angiotensin system in essential hypertension.
Topics: Angiotensin II; Angiotensinogen; Enzyme Precursors; Humans; Hypertension; Immunoradiometric Assay; Renin; Renin-Angiotensin System; Reproducibility of Results; Sodium Chloride, Dietary; Supine Position | 2001 |
Antisense inhibition of brain renin-angiotensin system decreased blood pressure in chronic 2-kidney, 1 clip hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Blood Pressure; Brain; Chronic Disease; Hypertension; Hypertension, Renovascular; Hypothalamus; Injections, Intraventricular; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2001 |
Paradoxical regulation of short promoter human renin transgene by angiotensin ii.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dose-Response Relationship, Drug; Gene Expression Regulation; Humans; Hydralazine; Infusion Pumps, Implantable; Kidney; Mice; Mice, Transgenic; Promoter Regions, Genetic; Renin; RNA, Messenger; Up-Regulation; Vasodilator Agents | 2001 |
Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Brain; Circadian Rhythm; Heart Rate; Hypertension; Locomotion; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Telemetry; Time Factors | 2001 |
Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes.
Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation | 2001 |
Responses to central Na(+) and ouabain are attenuated in transgenic rats deficient in brain angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Brain; Cerebrospinal Fluid; Heart Rate; Injections, Intraventricular; Male; Ouabain; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium | 2001 |
The peripheral renin-angiotensin system is not involved in the hypertension of sheep exposed to prenatal dexamethasone.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dexamethasone; Female; Glucocorticoids; Hypertension; Irbesartan; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Sheep; Tetrazoles; Vasoconstrictor Agents | 2001 |
Renin-angiotensin system in human failing hearts: message from nonmyocyte cells to myocytes.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cardiovascular Diseases; Heart Ventricles; Humans; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger | 2001 |
Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Cardiomyopathy, Dilated; Cardiovascular Diseases; Chymases; Endothelin-1; Gene Expression; Gene Expression Regulation; Heart Ventricles; Immunohistochemistry; In Situ Hybridization; Insulin-Like Growth Factor I; Iodine Radioisotopes; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Platelet-Derived Growth Factor; Protein Precursors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Ventricular Function, Left | 2001 |
Effects of angiotensin II on adipose conversion and expression of genes of the renin-angiotensin system in human preadipocytes.
Topics: Adipocytes; Adipose Tissue; Adult; Angiotensin II; Angiotensinogen; Carbohydrate Epimerases; Carrier Proteins; Cell Differentiation; Cell Division; Cells, Cultured; Culture Media, Serum-Free; Female; Gene Expression; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2001 |
Alcohol consumption is controlled by angiotensin II.
Topics: Alcohol Drinking; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Dopamine Antagonists; Energy Intake; Gene Transfer Techniques; Mice; Mice, Transgenic; Models, Animal; Peptidyl-Dipeptidase A; Receptors, Dopamine | 2001 |
Amelioration of angiotensin II-induced cardiac injury by a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiovascular Diseases; CD4 Antigens; CD8 Antigens; Collagen; Fibroblast Growth Factor 2; Fibronectins; Gene Expression Regulation; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Interleukin-6; Male; Myocardium; NF-kappa B; Oligonucleotides; Protein Binding; Pyridines; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Survival Analysis; Survival Rate; Transcription Factor AP-1 | 2001 |
Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Bosentan; Disease Progression; Endothelin-1; Endothelins; Gene Expression Regulation; Heart Failure; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Male; Organ Size; Peptidyl-Dipeptidase A; Protein Precursors; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Survival Analysis; Thiazepines; Time Factors | 2001 |
Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aspirin; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Gene Expression; Heart Diseases; Humans; I-kappa B Kinase; Kidney; Kidney Diseases; Macrophages; Monocytes; Myocarditis; Myocardium; Nephritis; NF-kappa B; Protein Serine-Threonine Kinases; Rats; Renin; Transcription Factor AP-1; Vascular Cell Adhesion Molecule-1 | 2001 |
Location of renin-angiotensin system components in the hypoglossal nucleus of the rat.
Topics: Angiotensin II; Angiotensinogen; Animals; Antibodies; Astrocytes; Brain Stem; Dendrites; Denervation; Hypoglossal Nerve; Immunohistochemistry; Male; Microscopy, Immunoelectron; Neurons; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Time Factors | 2001 |
Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Chymases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Mammary Arteries; Oligopeptides; Peptidyl-Dipeptidase A; Recombinant Proteins; Serine Endopeptidases; Substrate Specificity; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Adrenal response to angiotensin II in black hypertension: lack of sexual dimorphism.
Topics: Adrenal Glands; Adult; Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Black People; Female; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; Potassium; Potassium, Dietary; Renin; Sex Factors; White People | 2001 |
Effects of all-trans retinoic acid on renin-angiotensin system in rats with experimental nephritis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Antibodies; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Kidney Glomerulus; Male; Nephritis; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Thy-1 Antigens; Tretinoin | 2001 |
Albuminuria in mice after injection of antibodies against aminopeptidase A: role of angiotensin II.
Topics: Albuminuria; Aminopeptidases; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Glutamyl Aminopeptidase; Injections; Kidney; Mice; Mice, Inbred BALB C; Mice, Knockout; Microscopy, Electron | 2001 |
Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Binding Sites; Cathepsin G; Cathepsins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Inflammation; Models, Biological; Myeloblastin; Neutrophils; Pancreatic Elastase; Protein Binding; Serine Endopeptidases; Time Factors; Wound Healing | 2002 |
Vasoactive intestinal peptide down-regulates the intrahepatic renin-angiotensin system in the anaesthetized rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Down-Regulation; Gastrointestinal Agents; Liver; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Vasoactive Intestinal Peptide | 2000 |
Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cardiomegaly; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Heart; Humans; Intercellular Adhesion Molecule-1; Kidney; Models, Animal; Myocarditis; Necrosis; Nephritis; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Proline; Rats; Rats, Sprague-Dawley; Renin; Thiocarbamates; Vascular Cell Adhesion Molecule-1 | 2002 |
Urinary excretion of angiotensinogen reflects intrarenal angiotensinogen production.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension, Renal; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Vasoconstrictor Agents | 2002 |
Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin; Sodium Chloride, Dietary | 2002 |
Suppression of endotoxin-induced renal tumor necrosis factor-alpha and interleukin-6 mRNA by renin-angiotensin system inhibitors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Cytokines; Enalapril; Endotoxins; Gene Expression Regulation; Interleukin-6; Kidney; Lipopolysaccharides; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha | 2002 |
Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Brain; Cardiovascular System; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reference Values; Solitary Nucleus | 2002 |
Mature adipocytes inhibit in vitro differentiation of human preadipocytes via angiotensin type 1 receptors.
Topics: Adipocytes; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Biphenyl Compounds; Captopril; Cell Differentiation; Cells, Cultured; Coculture Techniques; Gene Expression; Humans; Irbesartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; Renin-Angiotensin System; Stem Cells; Tetrazoles; Transcription Factors | 2002 |
P450-dependent arachidonic acid metabolism and angiotensin II-induced renal damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hypertension, Renal; Kidney; Kinetics; Oxygenases; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Renin; Renin-Angiotensin System; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2002 |
Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cardiomegaly; Collagen; Fibrosis; Gene Targeting; Guanylate Cyclase; Heart Rate; Heart Ventricles; Hypertension; Imidazoles; Mice; Mice, Knockout; Myocardium; Natriuretic Peptide, Brain; Olmesartan Medoxomil; Organ Size; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Atrial Natriuretic Factor; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Ventricular Remodeling | 2002 |
Transendothelial transport of renin-angiotensin system components.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Biological Transport; Endothelium, Vascular; Enzyme Precursors; Horseradish Peroxidase; Humans; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Serine Proteinase Inhibitors; Serum Albumin; Umbilical Veins | 2002 |
Effects of dietary salt changes on renal renin-angiotensin system in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney Cortex; Kidney Medulla; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Diet, Sodium-Restricted; Kidney Cortex; Kidney Medulla; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Presence of cellular renin-angiotensin system in chromaffin cells of bovine adrenal medulla.
Topics: Adrenal Medulla; Angiotensin II; Angiotensinogen; Animals; Cattle; Cells, Cultured; Centrifugation, Isopycnic; Chromaffin Cells; Immunohistochemistry; In Situ Hybridization; Microscopy, Immunoelectron; Peptidyl-Dipeptidase A; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sucrose | 2002 |
Maternal glucocorticoid treatment programs alterations in the renin-angiotensin system of the ovine fetal kidney.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Western; Dexamethasone; Diuresis; Female; Gestational Age; Glomerular Filtration Rate; Glucocorticoids; Hydrocortisone; Hypertension; Immunohistochemistry; Kidney; Maternal-Fetal Exchange; Nucleic Acid Hybridization; Organ Size; Polymerase Chain Reaction; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Sheep | 2002 |
Brain-specific restoration of angiotensin II corrects renal defects seen in angiotensinogen-deficient mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Genetic Vectors; Kidney; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Radioimmunoassay; Ribonucleases; RNA; Time Factors; Water | 2003 |
Immunosuppressive treatment protects against angiotensin II-induced renal damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antigens, CD; B7-2 Antigen; Blood Pressure; Dendritic Cells; Dexamethasone; Etanercept; Histocompatibility Antigens Class II; Humans; Immunoglobulin G; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Kinetics; Macrophage Migration-Inhibitory Factors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mycophenolic Acid; NADPH Dehydrogenase; NADPH Oxidases; NF-kappa B; Phosphoproteins; Protective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor; Renin; T-Lymphocytes | 2002 |
Release of preformed Ang II from myocytes mediates angiotensinogen and ET-1 gene overexpression in vivo via AT1 receptor.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aortic Valve Stenosis; Cardiac Catheterization; Cytoplasm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart; Insulin-Like Growth Factor I; Microscopy, Confocal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stress, Mechanical; Swine; Systole; Tetrazoles; Valine; Valsartan | 2002 |
The predominant role of brain angiotensinogen and angiotensin in environmentally induced hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Cold Temperature; Disease Models, Animal; Hypertension; Hypothalamus; Liver; Male; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2002 |
Endothelin-converting enzyme inhibition ameliorates angiotensin II-induced cardiac damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aorta; Aspartic Acid Endopeptidases; Disease Models, Animal; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Extracellular Matrix; Fibroblast Growth Factor 2; Fibronectins; Heart Diseases; Heart Ventricles; Humans; Immunohistochemistry; Kidney; Male; Metalloendopeptidases; Prodrugs; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 2002 |
Urinary angiotensinogen as an indicator of intrarenal Angiotensin status in hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Antibodies; Biomarkers; Blood Pressure; Blotting, Western; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Kidney; Kinetics; Male; Rats; Rats, Sprague-Dawley | 2003 |
Endothelin-1 contributes to the Frank-Starling response in hypertrophic rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Animals, Genetically Modified; Benzimidazoles; Biphenyl Compounds; Bosentan; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Myocardial Contraction; Organ Culture Techniques; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Stress, Mechanical; Sulfonamides; Tetrazoles | 2003 |
Differential response of cardiac fibroblasts from young adult and senescent rats to ANG II.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Collagen; Fibroblasts; Gene Expression Regulation; Male; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transforming Growth Factor beta | 2003 |
A role for angiotensin II AT1 receptors in ureteric bud cell branching.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Communication; Collagen; Epithelial Cells; Gels; Gene Expression Regulation, Developmental; In Vitro Techniques; Kidney Medulla; Mice; Mice, Inbred C57BL; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Stromal Cells; Ureter; Vasoconstrictor Agents | 2003 |
Precocious activation of genes of the renin-angiotensin system and the fibrogenic cascade in IgA glomerulonephritis.
Topics: Adult; Angiotensin II; Angiotensinogen; Case-Control Studies; Collagen Type IV; Fibrosis; Gene Expression; Gene Expression Regulation; Glomerulonephritis, IGA; Humans; Kidney; Kidney Glomerulus; Kidney Tubules; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Activated human hepatic stellate cells express the renin-angiotensin system and synthesize angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Cells, Cultured; Fibroblasts; Hepatocytes; Humans; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Wound Healing | 2003 |
Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Body Weight; Cardiomegaly; Collagen; Hemodynamics; Losartan; Mice; Mice, Transgenic; Myocardium; Organ Size; Organ Specificity; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2003 |
Genetic determinants of nonmodulating hypertension.
Topics: Age Factors; Aldosterone; Angiotensin II; Angiotensinogen; Epistasis, Genetic; Family Health; Female; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Quantitative Trait Loci; Renin-Angiotensin System; Sex Factors | 2003 |
Differential regulation of in vivo angiogenesis by angiotensin II receptors.
Topics: Alginates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Cell Line, Tumor; Enalapril; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Transgenic; Microspheres; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2003 |
Elevated intracardiac angiotensin II leads to cardiac hypertrophy and mechanical dysfunction in normotensive mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Heart Rate; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Rats; Tachycardia, Ventricular; Ventricular Remodeling | 2003 |
The recovery of some components of the renin angiotensin system in the rat pancreas after chronic exposure to hypoxic condition.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Hypoxia; DNA Primers; Pancreas; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Up-Regulation | 2003 |
Ganglionic action of angiotensin contributes to sympathetic activity in renin-angiotensinogen transgenic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Chlorisondamine; Ganglia, Sympathetic; Ganglionic Blockers; Humans; Hypertension; Kidney; Losartan; Mice; Mice, Transgenic; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 2004 |
Evidence for a local angiotensin-generating system and dose-dependent inhibition of glucose-stimulated insulin release by angiotensin II in isolated pancreatic islets.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Blotting, Western; Dose-Response Relationship, Drug; Gene Expression; Glucose; Imidazoles; Immunohistochemistry; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Losartan; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Peptidyl-Dipeptidase A; Proinsulin; Protein Biosynthesis; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
Angiotensin II in the lesional skin of systemic sclerosis patients contributes to tissue fibrosis via angiotensin II type 1 receptors.
Topics: Adult; Aged; Angiotensin II; Angiotensinogen; Autocrine Communication; Blotting, Western; Cathepsin D; Cells, Cultured; Extracellular Matrix; Female; Fibroblasts; Fibrosis; Gene Expression; Humans; Immunohistochemistry; Male; Middle Aged; Procollagen; Receptor, Angiotensin, Type 1; RNA, Messenger; Scleroderma, Systemic; Skin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Endogenous angiotensin and pressure modulate brain angiotensinogen and AT1A mRNA expression.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Brain Stem; Gene Expression; Hypertension; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Solitary Nucleus | 2004 |
A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arachidonic Acid; Blotting, Western; Chromatography, Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Immunohistochemistry; Kidney; Kidney Diseases; Mass Spectrometry; NF-kappa B; Polymerase Chain Reaction; Rats; Receptors, Cytoplasmic and Nuclear; Renin; Transcription Factors; Vasoconstrictor Agents | 2004 |
Protective effects of endogenous adrenomedullin on cardiac hypertrophy, fibrosis, and renal damage.
Topics: Adrenomedullin; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Cardiomegaly; Collagen Type I; Constriction; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Fibrosis; Gene Expression Regulation; Genes, fos; Genes, Lethal; Glomerulosclerosis, Focal Segmental; Heterozygote; Male; MAP Kinase Signaling System; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptides; Peptidyl-Dipeptidase A; Protein Kinase C; Proto-Oncogene Proteins c-fos; Transforming Growth Factor beta; Ventricular Remodeling | 2004 |
Essential role for cathepsin D in bleomycin-induced apoptosis of alveolar epithelial cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis; Bleomycin; Cathepsin D; Cells, Cultured; DNA Fragmentation; Epithelial Cells; Male; Oligonucleotides, Antisense; Pulmonary Alveoli; Rats; Rats, Wistar; RNA, Messenger | 2004 |
Genetic polymorphisms of angiotensin system genes in congenital diaphragmatic hernia associated with persistent pulmonary hypertension.
Topics: Alleles; Angiotensin II; Angiotensinogen; Case-Control Studies; Gene Frequency; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Angiotensin; Renin-Angiotensin System | 2004 |
Adjacent expression of renin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model.
Topics: Amygdala; Angiotensin II; Angiotensinogen; Animals; beta-Galactosidase; Genes, Reporter; Green Fluorescent Proteins; Hippocampus; Lac Operon; Luminescent Proteins; Medulla Oblongata; Mice; Mice, Transgenic; Nerve Tissue Proteins; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Recombinant Fusion Proteins; Renin; Reticular Formation; Septal Nuclei; Subfornical Organ; Transgenes | 2004 |
AT1 receptor mediated augmentation of intrarenal angiotensinogen in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Imidazoles; Kidney; Kidney Tubules, Proximal; Male; Olmesartan Medoxomil; Proteinuria; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Tetrazoles | 2004 |
Prevention of sympathetic and cardiac dysfunction after myocardial infarction in transgenic rats deficient in brain angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Brain; DNA, Antisense; Genes, Synthetic; Glial Fibrillary Acidic Protein; Heart Rate; Hypothalamus; Injections, Intraventricular; Male; Myocardial Infarction; Organ Size; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex, Abnormal; Renin-Angiotensin System; Stress, Psychological; Stroke Volume; Sympathetic Nervous System; Transgenes; Ventricular Dysfunction, Left; Ventricular Remodeling | 2004 |
Androgens augment proximal tubule transport.
Topics: Absorption; Androgens; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dihydrotestosterone; Glomerular Filtration Rate; Kidney Tubules, Proximal; Male; Microvilli; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Testosterone; Weight Gain | 2004 |
All of the components required for angiotensin II formation are expressed locally in human atherosclerotic lesions, including a long suspected player cathepsin G.
Topics: Angiotensin II; Angiotensinogen; Carotid Artery Diseases; Carotid Artery, Common; Cathepsin D; Cathepsin G; Cathepsins; Humans; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; RNA, Messenger; Serine Endopeptidases | 2004 |
Inappropriately low angiotensin II generation: a factor determining reduced kidney function and survival in patients with decompensated cirrhosis.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Blood Volume; Case-Control Studies; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney; Liver; Liver Cirrhosis; Male; Middle Aged; Peptidyl-Dipeptidase A; Prospective Studies; Renal Circulation; Renin; Survival Analysis | 2004 |
The intrarenal renin-angiotensin system in autosomal dominant polycystic kidney disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antibodies; Blotting, Western; Cells, Cultured; Humans; Hypertension, Renal; Kidney; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Dominant; Rabbits; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA, Messenger | 2004 |
Angiotensin deficiency in mice leads to dilated cardiomyopathy.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomyopathy, Dilated; Disease Models, Animal; Echocardiography; Hemodynamics; Hypotension; Male; Mice; Mice, Knockout; Netherlands; Receptors, Angiotensin; Stroke Volume; Ventricular Function, Left | 2004 |
Renin-angiotensin system expression in rat bone marrow haematopoietic and stromal cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Biomarkers; Bone Marrow Cells; Cell Lineage; Cells, Cultured; Hematopoietic Stem Cells; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Stromal Cells | 2004 |
Insulin stimulates endogenous angiotensin II production via a mitogen-activated protein kinase pathway in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta; Cell Division; Cells, Cultured; Cytosol; Enzyme Inhibitors; Flavonoids; Hypoglycemic Agents; Immunohistochemistry; Insulin; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
Synthesis and secretion of angiotensin II by the prostate gland in vitro.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Line; Epithelium; Humans; Immunologic Techniques; Male; Organ Culture Techniques; Peptidyl-Dipeptidase A; Prostate; Puberty; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Distribution | 2005 |
A new HOPE for aldosterone blockade?
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Coronary Disease; Cytochrome P-450 CYP11B2; Drug Therapy, Combination; Endothelium, Vascular; Fibroblasts; Humans; Lipoproteins, LDL; Mice; Mice, Knockout; Mice, Transgenic; Mineralocorticoid Receptor Antagonists; Muscle, Smooth, Vascular; Myocytes, Cardiac; Nitric Oxide; Rats; Receptor, Angiotensin, Type 1; Receptors, LDL; Receptors, Mineralocorticoid; Receptors, Oxidized LDL; Recombinant Fusion Proteins; Renin; Scavenger Receptors, Class E; Signal Transduction | 2004 |
Differential modulation of baroreflex control of heart rate by neuron- vs. glia-derived angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Baroreflex; Blood Pressure; Brain; Cardiovascular Physiological Phenomena; Heart Rate; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Neuroglia; Neurons; Nitroprusside; Peptides; Phenylephrine; Propranolol; Renin | 2004 |
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Kidney; Peptides; Protein Conformation; Protein Precursors; Protein Structure, Tertiary; Rats; Renin; Renin-Angiotensin System; Urine | 2004 |
Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN.
Topics: Angiotensin II; Angiotensinogen; Animals; Paraventricular Hypothalamic Nucleus; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Species Specificity; Subfornical Organ | 2004 |
Reactive oxygen species blockade and action of insulin on expression of angiotensinogen gene in proximal tubular cells.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Azaserine; Cell Line; Gene Expression Regulation; Glucose; Imidazoles; Indicators and Reagents; Indoles; Insulin; Kidney Tubules, Proximal; Losartan; Maleimides; Perindopril; Protein Kinase C; Pyridines; Rats; Reactive Oxygen Species; Renin | 2004 |
Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Aortic Diseases; Arteriosclerosis; Chemokine CCL2; Chickens; Diet, Atherogenic; Female; Hypercholesterolemia; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, LDL; Renin-Angiotensin System; RNA, Messenger | 2004 |
Inducible NOS inhibition, eicosapentaenoic acid supplementation, and angiotensin II-induced renal damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arachidonic Acid; Eicosapentaenoic Acid; Enzyme Inhibitors; Humans; In Vitro Techniques; Kidney; Lysine; Male; Microsomes; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Renin; Transcription Factor AP-1 | 2005 |
Conversion of renin substrate tetradecapeptide to angiotensin II by rat MAB elastase-2.
Topics: Angiotensin II; Angiotensinogen; Animals; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Mesentery; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Serine Endopeptidases | 2004 |
Local umbilical cord blood renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Autocrine Communication; Cell Proliferation; Female; Fetal Blood; Hematopoiesis; Hematopoietic Stem Cells; Humans; Paracrine Communication; Peptidyl-Dipeptidase A; Pregnancy; Renin; Renin-Angiotensin System | 2005 |
Magnesium supplementation prevents angiotensin II-induced myocardial damage and CTGF overexpression.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Connective Tissue Growth Factor; Dietary Supplements; Fibrosis; Humans; Immediate-Early Proteins; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Magnesium; Male; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tacrolimus | 2005 |
Estradiol induces discordant angiotensin and blood pressure responses to orthostasis in healthy postmenopausal women.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Case-Control Studies; Estradiol; Female; Hemodynamics; Humans; Lower Body Negative Pressure; Middle Aged; Postmenopause; Posture; Renin; Renin-Angiotensin System | 2005 |
A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney Glomerulus; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2005 |
The renin-angiotensin system and the developing retinal vasculature.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Genetically Modified; Autoradiography; Immunoenzyme Techniques; Lisinopril; Losartan; Neovascularization, Physiologic; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Retinal Ganglion Cells; Retinal Vessels | 2005 |
Advanced glycation end-product-induced mitogenesis and collagen production are dependent on angiotensin II and connective tissue growth factor in NRK-49F cells.
Topics: Angiotensin II; Angiotensinogen; Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Collagen; Connective Tissue Growth Factor; DNA Primers; Glycation End Products, Advanced; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Mitosis; Oligonucleotides; RNA, Messenger; Transforming Growth Factor beta | 2005 |
Elevated dietary sodium intake exacerbates myocardial hypertrophy associated with cardiac-specific overproduction of angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Mice; Mice, Transgenic; Myocardium; Organ Size; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium, Dietary | 2004 |
Influence of elevated renin substrate on angiotensin II and arterial blood pressure in conscious mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Infusions, Intravenous; Male; Mice; Mice, Inbred C57BL; Renin | 2005 |
Expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Immunohistochemistry; Infant; Infant, Newborn; Kidney; Kidney Tubules; Polycystic Kidney, Autosomal Recessive; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2005 |
Enhanced intrarenal angiotensinogen contributes to early renal injury in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Kidney Diseases; Male; Rats; Rats, Inbred SHR | 2005 |
Aldosterone synthase inhibitor ameliorates angiotensin II-induced organ damage.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Fibrosis; Heart Diseases; Humans; Inflammation; Kidney Diseases; Losartan; Mineralocorticoid Receptor Antagonists; Myocardium; Rats; Renin | 2005 |
Effects of sodium intake on plasma potassium and renin angiotensin aldosterone system in conscious dogs.
Topics: Aldosterone; Angiotensin II; Angiotensinogen; Animals; Atrial Natriuretic Factor; Blood Pressure; Diuresis; Dogs; Female; Glomerular Filtration Rate; Heart Rate; Plasma Volume; Potassium; Renin; Renin-Angiotensin System; Sodium; Vasopressins | 2005 |
Angiotensin II-mediated phenotypic cardiomyocyte remodeling leads to age-dependent cardiac dysfunction and failure.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Calcium; Calcium-Transporting ATPases; Cardiac Output, Low; Cardiomegaly; Cardiomyopathy, Dilated; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Phenotype; Promoter Regions, Genetic; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Remodeling | 2005 |
Low renin-angiotensin system activity gene polymorphism and dysplasia associated with posterior urethral valves.
Topics: Angiotensin II; Angiotensinogen; Child; Chromosome Deletion; Female; Genetic Variation; Genotype; Humans; Kidney Failure, Chronic; Male; Odds Ratio; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Urethra | 2005 |
NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria.
Topics: Adenoviridae; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Carboxypeptidases; Dietary Proteins; Female; I-kappa B Proteins; Kidney; NF-kappa B; NF-KappaB Inhibitor alpha; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; RNA, Messenger | 2005 |
Autocrine regulation of internal anal sphincter tone by renin-angiotensin system: comparison with phasic smooth muscle.
Topics: Anal Canal; Angiotensin II; Angiotensinogen; Animals; Autocrine Communication; Blotting, Western; Captopril; Cell Size; Male; Muscle Tonus; Muscle, Smooth; Oligopeptides; Rectum; Renin-Angiotensin System | 2005 |
Cerebral vascular effects of angiotensin II: new insights from genetic models.
Topics: Angiotensin II; Angiotensinogen; Animals; Cerebral Arteries; Cerebrovascular Circulation; Endothelium, Vascular; Female; Humans; Hypertension; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Renin; rho-Associated Kinases; Sex Factors; Superoxides; Vasoconstriction | 2006 |
Glial-specific ablation of angiotensinogen lowers arterial pressure in renin and angiotensinogen transgenic mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Baroreflex; Blood Pressure; Brain; Mice; Mice, Transgenic; Neuroglia; Renin; Renin-Angiotensin System | 2005 |
Complement activation in angiotensin II-induced organ damage.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; C-Reactive Protein; Complement Activation; Complement C3; Complement Membrane Attack Complex; Humans; Interleukin-6; Kidney; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tumor Necrosis Factor-alpha | 2005 |
Central angiotensin II controls alcohol consumption via its AT1 receptor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Brain; Dopamine; Enalapril; Mice; Mice, Inbred C57BL; Rats; Receptor, Angiotensin, Type 1 | 2005 |
Acute exercise causes an enhancement of tissue renin-angiotensin system in the kidney in rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Western; Gene Expression Regulation; Kidney; Male; Muscle, Skeletal; Peptidyl-Dipeptidase A; Physical Exertion; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Spleen | 2005 |
Role of elastase-2 as an angiotensin II-forming enzyme in rat carotid artery.
Topics: Amino Acid Chloromethyl Ketones; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Carotid Artery, Common; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Oligopeptides; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Vasoconstriction | 2005 |
Upregulation of renal renin-angiotensin system in mouse diabetic nephropathy.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Immunohistochemistry; Insulin; Kidney; Male; Mice; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred MRL lpr; Organ Size; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Specific Pathogen-Free Organisms; Up-Regulation | 2005 |
Activation of protein kinase A by atrial natriuretic peptide in neonatal rat cardiac fibroblasts: role in regulation of the local renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Fibroblasts; Gene Expression Regulation; Indoles; Myocardium; Protein Kinase Inhibitors; Rats; Renin; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2005 |
Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bronchoalveolar Lavage Fluid; Ethanol; Glutathione Disulfide; Lisinopril; Lung; Male; Membrane Glycoproteins; Membrane Transport Proteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Phosphoproteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Superoxides | 2006 |
Direct regulation of insulin secretion by angiotensin II in human islets of Langerhans.
Topics: Angiotensin Amide; Angiotensin II; Angiotensinogen; Animals; Blotting, Western; Calcium; Cell Line; Cells, Cultured; Fluorometry; Gene Expression Regulation; Glucose; Humans; Imidazoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Mice; Nifedipine; Peptidyl-Dipeptidase A; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saralasin | 2006 |
Tissue-specific renin-angiotensin system in pulmonary lymphangioleiomyomatosis.
Topics: Actins; Adult; Angiotensin II; Angiotensinogen; Base Sequence; Female; Humans; Lung; Lymphangioleiomyomatosis; Mast Cells; Molecular Sequence Data; Organ Specificity; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger | 2006 |
Escherichia coli lipopolysaccharide inhibits renin activity in human mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endotoxemia; Escherichia coli; Humans; Lipopolysaccharides; Mesangial Cells; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Time Factors | 2006 |
Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.
Topics: Albumins; Amidohydrolases; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Arginine; Calcium Channel Blockers; Dihydropyridines; Gene Expression Regulation, Enzymologic; Hypertension; Kidney; Rats; Rats, Sprague-Dawley; Renin | 2006 |
Time course analysis of tyrosine hydroxylase and angiotensinogen mRNA expression in central nervous system of rats submitted to experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Aortic Coarctation; Blood Pressure; Brain; Brain Stem; Catecholamines; Disease Models, Animal; Gene Expression; Hypertension; Male; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred WKY; RNA, Messenger; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation | 2006 |
Renin increments the inward calcium current in the failing heart.
Topics: Angiotensin II; Angiotensinogen; Animals; Calcium; Cardiomyopathy, Dilated; Cricetinae; Extracellular Fluid; In Vitro Techniques; Intracellular Fluid; Mesocricetus; Myocytes, Cardiac; Renin | 2006 |
Localisation of renin-angiotensin system (RAS) components in breast.
Topics: Angiotensin II; Angiotensinogen; Breast Neoplasms; Female; Gene Expression Profiling; Humans; Immunohistochemistry; Mammary Glands, Human; Neoplasm Invasiveness; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Specific receptor for angiotensinogen on human renal cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Binding, Competitive; Cells, Cultured; Epithelial Cells; Humans; Iodine Radioisotopes; Kidney Tubules; Receptors, Angiotensin; Time Factors | 2006 |
Sustained renal interstitial macrophage infiltration following chronic angiotensin II infusions.
Topics: Angiotensin II; Angiotensinogen; Animals; Chemokine CCL2; Chemokines; Cytokines; Electrophoretic Mobility Shift Assay; Immunohistochemistry; Inflammation Mediators; Infusions, Intravenous; Kidney; Macrophages; Male; Matrix Metalloproteinase 9; NF-kappa B; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents | 2007 |
Genetic ablation of angiotensinogen in the subfornical organ of the brain prevents the central angiotensinergic pressor response.
Topics: Adenoviridae; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Female; Genetic Vectors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Recombinases; Renin; Subfornical Organ; Transfection | 2006 |
Letter by Krop et al regarding article, "Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium".
Topics: Angiotensin II; Angiotensinogen; Animals; Anti-Arrhythmia Agents; Buffers; Captopril; Diabetes Complications; Diabetes Mellitus, Experimental; Diffusion; Free Radical Scavengers; Imidazoles; Kallikreins; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Perfusion; Rats; Renin-Angiotensin System; Ribosomal Protein S6 Kinases, 90-kDa; Species Specificity; Tetrazoles | 2006 |
Influence of gender and genetic variability on plasma angiotensin peptides.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Genotype; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Sex Factors | 2006 |
Differential sympathetic and angiotensinergic responses in rats submitted to low- or high-salt diet.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Gene Expression Regulation; Hypertension; Kidney; Male; Rats; Rats, Wistar; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Sympathetic Nervous System | 2007 |
Angiotensin II increases adipose angiotensinogen expression.
Topics: Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blotting, Western; Gene Expression Regulation; Liver; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, LDL; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
p38 mitogen-activated protein kinase inhibition ameliorates angiotensin II-induced target organ damage.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Cardiovascular Diseases; Disease Models, Animal; Kidney Diseases; Male; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyrazoles; Rats; Rats, Sprague-Dawley; Renin | 2007 |
Endocrine role of the renin-angiotensin system in human adipose tissue and muscle: effect of beta-adrenergic stimulation.
Topics: Abdomen; Adipose Tissue; Angiotensin II; Angiotensinogen; Humans; Male; Middle Aged; Muscle, Skeletal; Obesity; Receptors, Adrenergic, beta; Regional Blood Flow; Renin-Angiotensin System | 2007 |
[Renin-angiotensin system in mesenteric adipose tissues in rats with metabolic syndrome].
Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Captopril; Cells, Cultured; Male; Metabolic Syndrome; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles | 2006 |
In vivo evidence for a role of adipose tissue SR-BI in the nutritional and hormonal regulation of adiposity and cholesterol homeostasis.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Adiposity; Angiotensin II; Angiotensinogen; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cell Membrane; Cholesterol; Cholesterol, HDL; DNA-Binding Proteins; Eating; Epididymis; Homeostasis; Insulin; Lipogenesis; Liver X Receptors; Male; Mice; Mice, Transgenic; Orphan Nuclear Receptors; Protein Transport; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Scavenger Receptors, Class B; Sterol Regulatory Element Binding Protein 1; Time Factors; Transcription, Genetic; Triglycerides | 2007 |
Angiotensin II-induced sudden arrhythmic death and electrical remodeling.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Cardiac Pacing, Artificial; Cardiomegaly; Connexin 43; Death, Sudden, Cardiac; Disease Models, Animal; Electrocardiography; Heart Conduction System; Hypertension; Losartan; Male; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Shal Potassium Channels; Tachycardia, Ventricular; Telemetry; Time Factors; Ventricular Remodeling | 2007 |
High-glucose-induced regulation of intracellular ANG II synthesis and nuclear redistribution in cardiac myocytes.
Topics: Actin Cytoskeleton; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Animals, Newborn; Benzimidazoles; Biphenyl Compounds; Cell Nucleus; Cells, Cultured; Chymases; Cytoplasm; Dose-Response Relationship, Drug; Extracellular Space; Glucose; Heart Ventricles; Isoproterenol; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sympathomimetics; Tetrazoles; Time Factors | 2007 |
Intracellular renin-angiotensin system: the tip of the intracrine physiology iceberg.
Topics: Actin Cytoskeleton; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Cell Nucleus; Chymases; Cytoplasm; Extracellular Space; Glucose; Isoproterenol; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction; Sympathomimetics; Tetrazoles | 2007 |
Nephrogenesis and the renal renin-angiotensin system in fetal sheep: effects of intrauterine growth restriction during late gestation.
Topics: Angiotensin II; Angiotensinogen; Animals; Body Weight; Erythrocyte Indices; Female; Fetal Growth Retardation; Fetal Weight; Fetus; Gene Expression; Gestational Age; Kidney; Nephrons; Organ Size; Pregnancy; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep | 2007 |
Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice.
Topics: Aging; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Humans; Kidney; Male; Mice; Mice, Transgenic; Organ Specificity; Renin | 2007 |
Involvement of an enterocyte renin-angiotensin system in the local control of SGLT1-dependent glucose uptake across the rat small intestinal brush border membrane.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Autocrine Communication; Blotting, Western; Enterocytes; Glucose; Ileum; Immunohistochemistry; In Vitro Techniques; Jejunum; Leucine; Losartan; Male; Microvilli; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Sodium-Glucose Transporter 1 | 2007 |
Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
Topics: Adult; Angiotensin II; Angiotensinogen; Animals; Astrocytes; Blood-Brain Barrier; Capillary Permeability; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cytokines; Endothelial Cells; Fetus; Gene Expression Regulation; Humans; Male; Membrane Microdomains; Membrane Proteins; Mice; Mice, Knockout; Middle Aged; Multiple Sclerosis; Occludin; Receptors, Angiotensin; S100 Proteins | 2007 |
Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence.
Topics: Adaptation, Physiological; Alcoholism; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Genetically Modified; Central Nervous System; Disease Models, Animal; Enalapril; Ethanol; Humans; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Antisense | 2007 |
Effects of resibufogenin in experimental hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Bufanolides; Creatinine; Desoxycorticosterone; Disease Models, Animal; Hypertension, Renal; Male; Mineralocorticoids; Proteinuria; Rats; Rats, Inbred Strains; Sodium Chloride; Superoxides; Vasoconstrictor Agents | 2008 |
The selective TP receptor antagonist, S18886 (terutroban), attenuates renal damage in the double transgenic rat model of hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Humans; Hypertension, Renal; Kidney Glomerulus; Male; Naphthalenes; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Renin; Vasoconstrictor Agents | 2008 |
Role of endogenously secreted angiotensin II in the CO2-induced stimulation of HCO3 reabsorption by renal proximal tubules.
Topics: Absorption; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bicarbonates; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Kidney Tubules, Proximal; Lisinopril; Peptidyl-Dipeptidase A; Rabbits; Renin-Angiotensin System | 2008 |
The role of local and systemic renin angiotensin system activation in a genetic model of sympathetic hyperactivity-induced heart failure in mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Heart Failure; Heart Rate; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Genetic; Myocytes, Cardiac; Norepinephrine; Physical Conditioning, Animal; Receptors, Adrenergic, alpha-2; Renin-Angiotensin System; Sympathetic Nervous System | 2008 |
Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy.
Topics: Alleles; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Blood Pressure; Blotting, Western; Cardiac Catheterization; Cardiomegaly; Connexin 43; DNA; Electrocardiography; Heart; Kidney; Mice; Mice, Knockout; Mice, Transgenic; Myocardium; Osmolar Concentration; Peptidyl-Dipeptidase A; Reverse Transcriptase Polymerase Chain Reaction; Tissue Distribution; Ventricular Function, Left | 2008 |
Angiotensin mediates renal fibrosis in the nephropathy of glycogen storage disease type Ia.
Topics: Angiotensin II; Angiotensinogen; Angiotensins; Animals; Connective Tissue Growth Factor; Extracellular Matrix; Fibrosis; Glucose-6-Phosphatase; Glycogen Storage Disease Type I; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Mice; Mice, Mutant Strains; Receptor, Angiotensin, Type 1; Transforming Growth Factor beta1 | 2008 |
Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis Regulatory Proteins; Cardiotonic Agents; Casein Kinase II; Catalase; Cell Membrane Permeability; Down-Regulation; Gene Expression Regulation, Enzymologic; Hypertrophy; Mice; Mice, Transgenic; Mitochondria, Heart; Muscle Proteins; Myocytes, Cardiac; Oxidation-Reduction; Phenylephrine; Phosphorylation; Protein Carbonylation; Protein Processing, Post-Translational; Rats; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2008 |
Sex differences in the pressor response to angiotensin II when the endogenous renin-angiotensin system is blocked.
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Drug Interactions; Eating; Enalapril; Estradiol; Female; Kidney Cortex; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sex Characteristics; Sodium Chloride, Dietary; Testosterone; Vasoconstrictor Agents | 2008 |
Activation of local chorionic villi angiotensin II levels but not angiotensin (1-7) in preeclampsia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Chorionic Villi; Female; Gene Expression; Humans; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2008 |
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Male; Neuroglia; Peptide Fragments; Rats; Renin-Angiotensin System; Solitary Nucleus; Tetrazoles | 2008 |
Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension; Male; Myocardium; Peptide Fragments; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Time Factors | 2008 |
Glomerular angiotensinogen protein is enhanced in pediatric IgA nephropathy.
Topics: Adolescent; Aldehydes; Angiotensin II; Angiotensinogen; Cell Count; Cells, Cultured; Child; Endothelial Cells; Gene Expression; Glomerulonephritis, IGA; Humans; Immunohistochemistry; Kidney Glomerulus; Mesangial Cells; Renin-Angiotensin System; Transforming Growth Factor beta; Vasoconstrictor Agents | 2008 |
Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Female; Hypertension; Kidney; Male; Mice; Myocardium; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Factors | 2008 |
Costimulation with angiotensin II and interleukin 6 augments angiotensinogen expression in cultured human renal proximal tubular cells.
Topics: Angiotensin II; Angiotensinogen; Cells, Cultured; Humans; Imidazoles; Interleukin-6; Kidney Tubules, Proximal; NF-kappa B; RNA, Messenger; STAT3 Transcription Factor; Tetrazoles; Up-Regulation | 2008 |
Relation between renin-angiotensin-aldosterone system and otosclerosis: a genetic association and in vitro study.
Topics: Adult; Alkaline Phosphatase; Angiotensin II; Angiotensinogen; Case-Control Studies; Cells, Cultured; Genotype; Humans; In Vitro Techniques; Interleukin-6; Middle Aged; Otosclerosis; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Stapes | 2008 |
Angiotensinogen genotype predicts abnormal renal hemodynamics in young hypertensive patients.
Topics: Adult; Age Factors; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Female; Genotype; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Renal Circulation; Renin-Angiotensin System; Vasoconstrictor Agents | 2008 |
Intrarenal angiotensin II and angiotensinogen augmentation in chronic angiotensin II-infused mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Organ Size; Receptor, Angiotensin, Type 1; Renin | 2008 |
Intracellular and extracellular renin have opposite effects on the regulation of heart cell volume. Implications for myocardial ischaemia.
Topics: Angiotensin II; Angiotensinogen; Animals; Bumetanide; Cardiomyopathy, Dilated; Cardiotonic Agents; Cell Separation; Cell Size; Cricetinae; Diuretics; Extracellular Space; Hypotonic Solutions; Myocardial Ischemia; Myocytes, Cardiac; Ouabain; Patch-Clamp Techniques; Renin; Serine Proteinase Inhibitors; Sodium-Potassium-Exchanging ATPase | 2008 |
Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cell Separation; Cells, Cultured; Coculture Techniques; Diuretics, Osmotic; Endothelin-1; Fibrosis; Leucine; Mannitol; Myocardium; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, Angiotensin; Renin; Thymidine; Transforming Growth Factor beta1; Tritium | 2008 |
Suppression of lipoprotein lipase expression in 3T3-L1 cells by inhibition of adipogenic differentiation through activation of the renin-angiotensin system.
Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Azo Compounds; Blotting, Western; Cell Differentiation; Lipoprotein Lipase; Mice; Microscopy, Phase-Contrast; Pioglitazone; PPAR gamma; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Thiazolidinediones; Valine; Valsartan | 2008 |
Angiotensin II upregulates renin-angiotensin system in human isolated T lymphocytes.
Topics: Adult; Angiotensin II; Angiotensinogen; Female; Gene Expression; Humans; In Vitro Techniques; Interferon-gamma; Lipopolysaccharides; Male; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; T-Lymphocytes | 2008 |
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Disease Models, Animal; Flavonoids; Irbesartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling | 2008 |
Intrarenal RAS activity and urinary angiotensinogen excretion in anti-thymocyte serum nephritis rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Antilymphocyte Serum; Blood Pressure; Gene Expression; Glomerulonephritis, Membranoproliferative; Imidazoles; Kidney; Male; Proteinuria; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles | 2008 |
Activation of renin-angiotensin system induces osteoporosis independently of hypertension.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bone Remodeling; Humans; Hypertension; Mice; Osteoblasts; Osteoporosis; RANK Ligand; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2009 |
A haplotype of human angiotensinogen gene containing -217A increases blood pressure in transgenic mice compared with -217G.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Circadian Rhythm; Genetic Predisposition to Disease; Haplotypes; Humans; Hypertension; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Renin; RNA, Messenger; Transcription, Genetic | 2008 |
Future directions in cardiovascular pharmacology: examples from the Renin-Angiotensin system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cardiovascular Diseases; Cardiovascular System; Humans; Pharmaceutical Preparations; Renin; Renin-Angiotensin System | 2008 |
Exaggeration of focal cerebral ischemia in transgenic mice carrying human Renin and human angiotensinogen genes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Brain Chemistry; Brain Ischemia; Capillaries; Cerebrovascular Circulation; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Transgenic; Oxidative Stress; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tetrazoles; Valine; Valsartan | 2009 |
Regulation of T-cell function by endogenously produced angiotensin II.
Topics: Adoptive Transfer; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensinogen; Animals; Autocrine Communication; Blood Pressure; Catalase; Cells, Cultured; Homeodomain Proteins; Imidazoles; Infusion Pumps, Implantable; Losartan; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Polyethylene Glycols; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Superoxide Dismutase; Superoxides; T-Lymphocytes; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Cardiac chymase converts rat proAngiotensin-12 (PA12) to angiotensin II: effects of PA12 upon cardiac haemodynamics.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Chromatography, High Pressure Liquid; Chymases; Coronary Vessels; Creatine Kinase; Hemodynamics; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Oligopeptides; Peptide Fragments; Perfusion; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Serine Proteinase Inhibitors; Tandem Mass Spectrometry; Time Factors; Troponin I; Vasoconstriction; Ventricular Function, Left | 2009 |
Dietary fish oil is antihypertrophic but does not enhance postischemic myocardial function in female mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Arrhythmias, Cardiac; Dietary Fats, Unsaturated; Disease Models, Animal; Estrogens; Female; Fish Oils; Genetic Predisposition to Disease; Hypertrophy; Mice; Mice, Transgenic; Myocardial Ischemia; Myocardium; Ovariectomy; Reperfusion Injury | 2009 |
Therapeutic targets in liver transplantation: angiotensin II in nonsteatotic grafts and angiotensin-(1-7) in steatotic grafts.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Apoptosis; Fatty Liver; Graft Survival; Health; Liver Transplantation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Rats; Receptors, Angiotensin | 2009 |
A new addition to the renin-angiotensin peptide family: proAngiotensin-12 (PA12).
Topics: Angiotensin II; Angiotensinogen; Animals; Biomarkers; Blood Pressure; Chymases; Coronary Vessels; Creatine Kinase; Hemodynamics; Humans; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Renin-Angiotensin System; Troponin I; Vasoconstriction; Ventricular Function, Left | 2009 |
Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Kidney; Male; Models, Animal; Myocardium; Nephrectomy; Peptide Fragments; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 2009 |
Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensinogen; Base Sequence; Cell Line; Chromatin Immunoprecipitation; DNA Primers; Electrophoretic Mobility Shift Assay; Gene Expression Regulation; Humans; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT5 Transcription Factor; Transcription Factor AP-1 | 2009 |
Effect of angiotensin II and bradykinin inhibition in rat reduced-size liver transplantation.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Flow Velocity; Bradykinin; Hepatic Artery; Imidazoles; Liver; Liver Circulation; Liver Transplantation; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Portal Vein; Proliferating Cell Nuclear Antigen; Pyridines; Rats; Regeneration; RNA, Messenger | 2009 |
Endogenous angiotensinergic system in neurons of rat and human trigeminal ganglia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Humans; Immunohistochemistry; In Situ Hybridization; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred WKY; RNA, Messenger; Trigeminal Ganglion | 2009 |
The ontogeny of components of the renin-angiotensin system in the porcine fetal ovary.
Topics: Angiotensin II; Angiotensinogen; Animals; Blotting, Western; Female; Gestational Age; Ovary; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine | 2010 |
Renal damage inhibited in mice lacking angiotensinogen gene subjected to unilateral ureteral obstruction.
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Fibrosis; Kidney Diseases; Mice; Mice, Inbred C57BL; Ureteral Obstruction | 2009 |
Angiotensin II-mediated adaptive and maladaptive remodeling of cardiomyocyte excitation-contraction coupling.
Topics: Angiotensin II; Angiotensinogen; Animals; Calcium; Cardiomegaly; Electrophysiologic Techniques, Cardiac; Mice; Mice, Transgenic; Myocardial Contraction; Myocytes, Cardiac; Sodium-Calcium Exchanger | 2009 |
Oxidized low-density lipoprotein, angiotensin II and increased waist cirumference are associated with valve inflammation in prehypertensive patients with aortic stenosis.
Topics: Adiponectin; Angiotensin I; Angiotensin II; Angiotensinogen; Aortic Valve Stenosis; Biomarkers; Blood Pressure; Humans; Interleukin-6; Linear Models; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Myocarditis; Oxidative Stress; Prehypertension; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Waist Circumference | 2010 |
Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist.
Topics: Albuminuria; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Ergocalciferols; Fibrosis; Glomerular Basement Membrane; Inflammation Mediators; Losartan; Macrophages; Mice; Mice, Inbred DBA; Podocytes; Renin; Renin-Angiotensin System; Time Factors; Vitamins | 2009 |
IL-6 augments angiotensinogen in primary cultured renal proximal tubular cells.
Topics: Angiotensin II; Angiotensinogen; Antibodies; Cells, Cultured; Epithelial Cells; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-6; Kidney Tubules, Proximal; NF-kappa B; Receptors, Interleukin-6; RNA, Messenger; STAT3 Transcription Factor; Time Factors; Tumor Necrosis Factor-alpha | 2009 |
Effect of adrenotensin on cell proliferation is mediated by angiotensin II in cultured rat mesangial cells.
Topics: Adrenomedullin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cell Line; Cell Proliferation; Collagen Type IV; Gene Expression Regulation; Losartan; Mesangial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Renin; RNA, Messenger; Transforming Growth Factor beta1 | 2009 |
Exaggerated blood pressure variability superimposed on hypertension aggravates cardiac remodeling in rats via angiotensin II system-mediated chronic inflammation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chemokine CCL2; Chronic Disease; Disease Models, Animal; Heart Diseases; Heart Ventricles; Hypertension; Hypertrophy; Inflammation; Macrophages; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Transforming Growth Factor beta; Ventricular Remodeling | 2009 |
Inhibition of intracellular angiotensin II formation blocks high glucose effect on mesangial matrix.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Base Sequence; Cells, Cultured; DNA Primers; Enzyme-Linked Immunosorbent Assay; Fibronectins; Gene Knockdown Techniques; Glomerular Mesangium; Glucose; Humans; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta1 | 2009 |
Ischemia-induced brain damage is enhanced in human renin and angiotensinogen double-transgenic mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Blood Pressure; Brain; Brain Ischemia; Cell Death; Disease Models, Animal; Humans; Infarction, Middle Cerebral Artery; Losartan; Male; Mice; Mice, Transgenic; Receptor, Angiotensin, Type 1; Regional Blood Flow; Renin; Severity of Illness Index; Signal Transduction | 2009 |
Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Glucose; Kidney Tubules, Proximal; Mice; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2010 |
Prenatal dehydration alters renin-angiotensin system associated with angiotensin-increased blood pressure in young offspring.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Baroreflex; Birth Weight; Blood Pressure; Female; Fetal Development; Gene Expression; Heart; Heart Rate; Hypertension; Liver; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Water Deprivation | 2009 |
[Establishment of a diabetic-hypertensive rat model].
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Blood Pressure Determination; Diabetes Mellitus, Experimental; Endothelin-1; Hypertension; Kidney; Male; Rats; Rats, Wistar | 2009 |
Stress sensitivity is increased in transgenic rats with low brain angiotensinogen.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 2; Receptor, Melanocortin, Type 2; Renin-Angiotensin System; RNA, Messenger; Stress, Physiological; Swimming; Up-Regulation | 2010 |
Prorenin contributes to angiotensin peptide formation in transgenic rats with rat prorenin expression targeted to the liver.
Topics: alpha 1-Antitrypsin; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Humans; Hypertension, Renal; Hypertrophy, Left Ventricular; Kidney; Liver; Male; Myocardium; Nephrectomy; Organ Size; Rats; Rats, Inbred F344; Rats, Transgenic; Renin; Transgenes | 2009 |
Major role for ACE-independent intrarenal ANG II formation in type II diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Arterioles; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Kidney; Male; Mice; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Serine Proteases; Signal Transduction; Vasoconstriction | 2010 |
Intrarenal mouse renin-angiotensin system during ANG II-induced hypertension and ACE inhibition.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 2010 |
Fibronectin synthesis by high glucose level mediated proliferation of mouse embryonic stem cells: Involvement of ANG II and TGF-beta1.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Calcium Signaling; Cell Count; Cell Proliferation; DNA Replication; Embryonic Stem Cells; Fibronectins; Glucose; Hyperglycemia; JNK Mitogen-Activated Protein Kinases; Losartan; Mice; Phosphorylation; Protein Kinase C; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low- or high-salt feeding in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Male; Radioimmunoassay; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride | 2010 |
Adaptation of a corticosterone ELISA to demonstrate sequence-specific effects of angiotensin II peptides and C-type natriuretic peptide on 1alpha-hydroxycorticosterone synthesis and steroidogenic mRNAs in the elasmobranch interrenal gland.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Cholesterol Side-Chain Cleavage Enzyme; Corticosterone; Elasmobranchii; Enzyme-Linked Immunosorbent Assay; Female; Male; Molecular Sequence Data; Natriuretic Peptide, C-Type; Phosphoproteins; RNA, Messenger; Sequence Alignment | 2010 |
Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cardiomegaly; Genes; Heart; Humans; Hypertension; Male; Mitochondria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Resveratrol; Stilbenes | 2010 |
Regional vascular response to ProAngiotensin-12 (PA12) through the rat arterial system.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Arteries; Captopril; Chymases; Drug Stability; Hypertension; In Vitro Techniques; Male; Oligopeptides; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2010 |
Histone deacetylases are critical regulators of the renin-angiotensin system during ureteric bud branching morphogenesis.
Topics: Acetylation; Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Gestational Age; Histone Deacetylase 1; Histone Deacetylase Inhibitors; Histones; Hydroxylamines; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphogenesis; Phosphoproteins; Quinolines; Renin-Angiotensin System; RNA, Messenger; Tissue Culture Techniques; Ureter | 2010 |
Losartan inhibits LPS-induced inflammatory signaling through a PPARgamma-dependent mechanism in human THP-1 macrophages.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Atherosclerosis; Cell Line; Gene Expression; Humans; Hypertension; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Losartan; Macrophages; Monocytes; Phosphorylation; PPAR gamma; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Signal Transduction | 2010 |
Escherichia coli lipopolysaccharide impairs the calcium signaling pathway in mesangial cells: role of angiotensin II receptors.
Topics: Angiotensin II; Angiotensinogen; Blotting, Western; Calcium Signaling; Escherichia coli; Gene Expression Profiling; Humans; Lipopolysaccharides; Mesangial Cells; Nitric Oxide; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
Effects of circulating and local uteroplacental angiotensin II in rat pregnancy.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Brain; Cell Movement; Crosses, Genetic; Female; Fetal Growth Retardation; Humans; Liver; Male; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy, Animal; Rats; Renin; Trophoblasts; Up-Regulation; Uterus | 2010 |
Angiotensin AT1 receptor activation mediates high glucose-induced epithelial-mesenchymal transition in renal proximal tubular cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cadherins; Cell Line; Epithelial Cells; Epithelial-Mesenchymal Transition; Extracellular Matrix; Fibronectins; Glucose; Hyperglycemia; Kidney; Kidney Tubules, Proximal; Losartan; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Transforming Growth Factor beta1 | 2010 |
Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Body Weight; Cytochrome P-450 CYP1A1; Humans; Hypertension, Malignant; Male; Middle Aged; Rats; Rats, Transgenic; Renin; Tetrazoles | 2010 |
Intrarenal suppression of angiotensin II type 1 receptor binding molecule in angiotensin II-infused mice.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Cell Membrane; Epithelial Sodium Channels; Immunohistochemistry; Kidney; Kidney Medulla; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; NADPH Oxidases; Reverse Transcriptase Polymerase Chain Reaction | 2010 |
The renin-angiotensin system and hypertension in autosomal recessive polycystic kidney disease.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Kidney; Male; Mutation; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Time Factors | 2010 |
Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure.
Topics: Angiotensin II; Angiotensinogen; Animals; bcl-2-Associated X Protein; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Heart; Heart Failure; Heart Rate; Humans; Hydrazones; Hypertension; Major Histocompatibility Complex; Male; Pyridazines; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Simendan | 2010 |
The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance.
Topics: Adrenal Glands; Angiotensin II; Angiotensinogen; Animals; Brain; Energy Metabolism; Gene Expression; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Polyuria; Promoter Regions, Genetic; Renin; Renin-Angiotensin System; Steroids; Sympathetic Nervous System; Synapsins; Thermogenesis | 2010 |
Enhancement of renin and prorenin receptor in collecting duct of Cyp1a1-Ren2 rats may contribute to development and progression of malignant hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Cytochrome P-450 CYP1A1; Gene Expression; Hypertension, Malignant; Indoles; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Prorenin Receptor; Rats; Rats, Transgenic; Receptors, Cell Surface; Renin; Renin-Angiotensin System | 2011 |
Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.
Topics: Amiodarone; Angiotensin II; Angiotensinogen; Anti-Arrhythmia Agents; Apoptosis; Cell Survival; Cells, Cultured; Epithelial Cells; Humans; In Situ Nick-End Labeling; Lung; Necrosis; RNA, Messenger | 2011 |
Angiotensinergic and noradrenergic neurons in the rat and human heart.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cathepsin D; Dopamine beta-Hydroxylase; Female; Gene Expression; Heart Atria; Humans; Immunohistochemistry; In Situ Hybridization; Male; Middle Aged; Neurons; Neurotransmitter Agents; Norepinephrine; Rats; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Synapses; Ventricular Septum; Vesicular Acetylcholine Transport Proteins | 2011 |
Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apelin; Captopril; Cells, Cultured; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Losartan; Mice; Perindopril; Pyridines; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger | 2011 |
The hypothalamic arcuate nucleus: a new site of cardiovascular action of angiotensin-(1-12) and angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Arcuate Nucleus of Hypothalamus; Blood Pressure; Cardiovascular System; Chymases; Male; Microinjections; Muscimol; Peptide Fragments; Rats; Rats, Wistar; Splanchnic Nerves; Vagus Nerve | 2011 |
Characterization of a native angiotensin from an anciently diverged serine protease inhibitor in lamprey.
Topics: Analysis of Variance; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Heart Rate; Lampreys; Radioimmunoassay; RNA, Messenger | 2011 |
Angiotensinogen metabolism in rat aorta: robust formation of proangiotensin-12.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Aorta; Male; Peptide Fragments; Rats; Rats, Wistar; Renin; Renin-Angiotensin System | 2010 |
The roles of angiotensin II in stretched periodontal ligament cells.
Topics: Adult; Alkaline Phosphatase; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Dental Stress Analysis; Female; Fibroblasts; Gene Expression; Humans; Male; Osteoprotegerin; Periodontal Ligament; RANK Ligand; Rats; Recombinant Proteins; Stress, Mechanical; Transforming Growth Factor beta1; Up-Regulation | 2011 |
Visfatin stimulates a cellular renin-angiotensin system in cultured rat mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cell Line; Diabetic Nephropathies; Glomerular Mesangium; Nicotinamide Phosphoribosyltransferase; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger | 2011 |
Rho-kinase/nuclear factor-κβ/angiotensinogen axis in angiotensin II-induced renal injury.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensinogen; Animals; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; rho-Associated Kinases | 2011 |
Regulation of angiotensinogen by angiotensin II in mouse primary astrocyte cultures.
Topics: Adenoviridae; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Astrocytes; Benzimidazoles; Biphenyl Compounds; Brain; Brain Chemistry; Cells, Cultured; Dexamethasone; Feedback, Physiological; Imidazoles; Immunohistochemistry; Inositol Phosphates; Liver; Mice; Mice, Inbred C57BL; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrazoles | 2011 |
Increased renin excretion is associated with augmented urinary angiotensin II levels in chronic angiotensin II-infused hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 2011 |
Adverse host factors exacerbate occult HIV-associated nephropathy.
Topics: AIDS-Associated Nephropathy; Angiotensin II; Angiotensinogen; Animals; Biomarkers; Blood Pressure; Connective Tissue Growth Factor; Doxycycline; Epithelial-Mesenchymal Transition; Female; Gene Dosage; Genes, vpr; Host-Pathogen Interactions; Kidney; Male; Mice; Mice, Transgenic; Peptidyl-Dipeptidase A; Phenotype; Proteinuria; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2011 |
AT1 receptor-mediated augmentation of angiotensinogen, oxidative stress, and inflammation in ANG II-salt hypertension.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Hypertension; Kidney; Male; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary | 2012 |
Angiotensin II type I receptor blockade suppresses glomerular renin-angiotensin system activation, oxidative stress, and progressive glomerular injury in rat anti-glomerular basement membrane glomerulonephritis.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Anti-Glomerular Basement Membrane Disease; Glomerular Basement Membrane; Kidney Glomerulus; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred WKY; Renin-Angiotensin System; Superoxides; Transforming Growth Factor beta1; Translational Research, Biomedical | 2011 |
Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Brain; Brain Edema; Brain Ischemia; Hypotension; Ischemia; Rats; Rats, Sprague-Dawley; Tetrazoles; Time Factors | 2011 |
Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Body Weight; Imidazolidines; Kidney; Losartan; Male; Myocardium; Organ Size; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 2012 |
Augmented intratubular renin and prorenin expression in the medullary collecting ducts of the kidney as a novel mechanism of angiotensin II-induced hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Male; Renin | 2011 |
Caloric restriction ameliorates angiotensin II-induced mitochondrial remodeling and cardiac hypertrophy.
Topics: Angiotensin II; Angiotensinogen; Animals; Apoptosis; Autophagy; Blood Pressure; Body Temperature; Caloric Restriction; Cardiomegaly; Endoplasmic Reticulum Stress; Energy Metabolism; Heart Rate; Humans; Mitochondria; Mitochondrial Diseases; Myocytes, Cardiac; Oxidative Stress; Proteome; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Survival Rate; Vasoconstrictor Agents | 2012 |
Cardiovascular actions of angiotensin-(1-12) in the hypothalamic paraventricular nucleus of the rat are mediated via angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Cardiovascular System; Chymases; Heart Rate; Imidazoles; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 2012 |
Carboxypeptidases A1 and A2 from the perfusate of rat mesenteric arterial bed differentially process angiotensin peptides.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Base Sequence; Carboxypeptidases A; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Kinetics; Mesenteric Arteries; Molecular Sequence Data; Organ Specificity; Peptide Fragments; Perfusion; Rats | 2012 |
Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue.
Topics: Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Animals; Chymases; Female; Gene Expression Regulation, Enzymologic; Heart Atria; Humans; Male; Middle Aged; Myocytes, Cardiac; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Transport; Rats | 2011 |
Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Heart Rate; Hypothalamus; Male; Morpholines; Neurons; Peptide Fragments; PTEN Phosphohydrolase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vanadium Compounds | 2012 |
Angiotensin II regulates growth of the developing papillas ex vivo.
Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Biphenyl Compounds; Cell Proliferation; Female; Homeodomain Proteins; Kidney Medulla; Male; Mice; Mice, Knockout; Models, Animal; Morphogenesis; Receptor, Angiotensin, Type 1; Tetrazoles | 2012 |
Cardiac lineage protein-1 (CLP-1) regulates cardiac remodeling via transcriptional modulation of diverse hypertrophic and fibrotic responses and angiotensin II-transforming growth factor β (TGF-β1) signaling axis.
Topics: Angiotensin II; Angiotensinogen; Animals; Cardiomegaly; Extracellular Matrix; Fibroblasts; Fibrosis; Heterozygote; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myosin Heavy Chains; RNA-Binding Proteins; Signal Transduction; Smad3 Protein; STAT3 Transcription Factor; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta1; Ventricular Remodeling | 2012 |
Differential effects of high-fat diet on myocardial lipid metabolism in failing and nonfailing hearts with angiotensin II-mediated cardiac remodeling in mice.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet, High-Fat; Dietary Fats; Fatty Acids; Heart Failure; Hypertrophy, Left Ventricular; Lipid Metabolism; Male; Mice; Mice, Transgenic; Models, Animal; Myocardial Contraction; Myocardium; Oxidation-Reduction; Palmitates; Triglycerides; Ventricular Remodeling | 2012 |
Effects of proangiotensin-12 infused continuously over 14 days in conscious rats.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Cardiomegaly; Heart; Hypertension; Infusions, Subcutaneous; Male; Myocardium; Organ Size; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Time Factors; Vasoconstrictor Agents; Weight Gain | 2012 |
Role of H(2)O(2) in hypertension, renin-angiotensin system activation and renal medullary disfunction caused by angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Biomarkers; Catalase; Gene Expression Regulation; Hydrogen Peroxide; Hypertension; Kidney Diseases; Kidney Medulla; Male; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2012 |
Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Hypertension; Kidney; Lisinopril; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin | 2012 |
Liver angiotensinogen is the primary source of renal angiotensin II.
Topics: Angiotensin II; Angiotensinogen; Animals; Kidney; Liver; Low Density Lipoprotein Receptor-Related Protein-2; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Models, Animal; Phenotype; RNA, Messenger | 2012 |
Brain-targeted (pro)renin receptor knockdown attenuates angiotensin II-dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Baroreflex; Blood Pressure; Blotting, Western; Brain; Cell Line, Tumor; Humans; Hypertension; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Vasopressins | 2012 |
Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chymases; Colonic Neoplasms; Diabetes Complications; Diabetes Mellitus; Glucose; Glycated Hemoglobin; HT29 Cells; Humans; Hyperglycemia; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Oligoribonucleotides, Antisense; Receptor, Angiotensin, Type 1; Renin; RNA Interference; RNA, Small Interfering | 2012 |
High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Hypertension, Renal; Kidney; Kidney Cortex; Male; Mass Spectrometry; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Sodium, Dietary; Spectrometry, Mass, Electrospray Ionization | 2012 |
The increasing complexity of the intratubular Renin-Angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Kidney; Liver; Male | 2012 |
Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Arterial Pressure; Captopril; Chymases; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylethanolamine N-Methyltransferase; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System | 2013 |
Blood pressure and renin-angiotensin system resetting in transgenic rats with elevated plasma Val5-angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Feedback, Physiological; Genotype; Hypertension; Kidney; Lisinopril; Male; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System | 2012 |
Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hemodynamics; Hypertension; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Factors; Sodium Chloride, Dietary | 2012 |
Antenatal maternal protein deprivation: sexually dimorphic programming of the pancreatic renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Glucose; Dietary Proteins; Female; Gene Expression Regulation; Infant, Low Birth Weight; Male; Malnutrition; Mice; Pancreas; Peptidyl-Dipeptidase A; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA, Messenger; Sex Characteristics | 2013 |
Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation; Hypertension; Ion Channels; JNK Mitogen-Activated Protein Kinases; Male; Medulla Oblongata; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oligonucleotides, Antisense; Oxidative Stress; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Signal Transduction; Uncoupling Protein 2 | 2012 |
Expression of angiotensin II and its receptors in cyclosporine-induced gingival overgrowth.
Topics: Adult; Angiotensin II; Angiotensinogen; Case-Control Studies; Cells, Cultured; Chronic Periodontitis; Cyclosporine; Female; Fibroblasts; Gingival Overgrowth; Humans; Immunosuppressive Agents; Male; Middle Aged; Receptors, Angiotensin; Renin-Angiotensin System; Young Adult | 2013 |
Activation of the renin-angiotensin system by a low-salt diet does not augment intratubular angiotensinogen and angiotensin II in rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2013 |
Aberrant activation of the intrarenal renin-angiotensin system in the developing kidneys of type 2 diabetic rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Blood Glucose; Blood Pressure; Body Weight; Collagen; Connective Tissue Growth Factor; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Kidney; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred OLETF; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Time Factors; Transforming Growth Factor beta | 2013 |
Apelin effects on blood pressure and RAS in DOCA-salt-induced hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Aorta; Apelin; Apelin Receptors; Blood Pressure; Desoxycorticosterone Acetate; Endothelin-1; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2013 |
Diet composition modulates expression of sirtuins and renin-angiotensin system components in adipose tissue.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cholesterol, HDL; Diet, High-Fat; Dietary Fats; Dietary Proteins; Dietary Sucrose; Glucose; Lipids; Male; Mice; Mice, Inbred Strains; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sirtuins; Triglycerides | 2013 |
Preovulatory changes in the angiotensin II system in bovine follicles.
Topics: Angiotensin II; Angiotensinogen; Animals; Cattle; Cells, Cultured; Female; Fertility Agents, Female; Follicular Fluid; Gonadotropin-Releasing Hormone; Granulosa Cells; Luteinizing Hormone; Ovarian Follicle; Peptidyl-Dipeptidase A; Proestrus; Progesterone; Prostaglandins; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Theca Cells; Tissue Culture Techniques; Up-Regulation | 2013 |
A possible interaction between systemic and renal angiotensinogen in the control of blood pressure.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Kidney Tubules, Proximal; Liver; Male; Mice; Mice, Transgenic; Sodium, Dietary | 2013 |
Urinary angiotensinogen as a marker of intrarenal angiotensin II activity in adolescents with primary hypertension.
Topics: Adolescent; Angiotensin II; Angiotensinogen; Biomarkers; Body Mass Index; Chi-Square Distribution; Child; Creatinine; Cross-Sectional Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hypertension; Hyperuricemia; Kidney; Linear Models; Lipids; Male; Multivariate Analysis; Predictive Value of Tests; Prospective Studies; Up-Regulation; Uric Acid | 2013 |
High-salt diets during pregnancy affected fetal and offspring renal renin-angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Animals; Electrolytes; Female; Fetal Blood; Gene Expression Regulation, Developmental; Kidney; Male; Maternal Nutritional Physiological Phenomena; Peptidyl-Dipeptidase A; Pregnancy; Receptors, Angiotensin; Renal Insufficiency; Renin-Angiotensin System; RNA, Messenger; Sheep, Domestic; Sodium Chloride, Dietary; Urine; Vasopressins | 2013 |
Periaortic adipose tissue-specific activation of the renin-angiotensin system contributes to atherosclerosis development in uninephrectomized apoE-/- mice.
Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Cholesterol, Dietary; Disease Models, Animal; Insulin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; PPAR gamma; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2013 |
Angiotensin-[1-12] interacts with angiotensin type I receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Male; Membrane Potentials; Peptide Fragments; Phosphorylation; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Transfection | 2014 |
Amelioration of angiotensin II-induced salt-sensitive hypertension by liver-type fatty acid-binding protein in proximal tubules.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fatty Acid-Binding Proteins; Hypertension; Inflammation; Kidney; Kidney Tubules, Proximal; Mice; Mice, Transgenic; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System | 2013 |
Role of renin-angiotensin system in activation of macrophages by modified lipoproteins.
Topics: Acetyl-CoA C-Acetyltransferase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cathepsin G; Cell Line, Tumor; Cholesterol Esters; Foam Cells; Humans; Lipoproteins, LDL; Macrophages; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class A; Time Factors | 2013 |
Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia.
Topics: Angiotensin II; Angiotensinogen; Animals; Calcium; Carotid Body; Fura-2; Hypoxia; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sleep Apnea Syndromes; Tyrosine 3-Monooxygenase; Up-Regulation | 2014 |
ELISA examining urinary angiotensinogen as a potential indicator of intrarenal renin-angiotensin system (RAS) activity: a clinical study of 128 chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensinogen; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Regression Analysis; Renal Insufficiency, Chronic; Renin-Angiotensin System; Young Adult | 2013 |
Novel role of mechanosensitive AT1B receptors in myogenic vasoconstriction.
Topics: Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Male; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Receptor, Angiotensin, Type 1; RNA, Messenger; Vasoconstriction | 2014 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Disease Progression; Down-Regulation; Fumarates; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Ramipril; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2014 |
Podocyte injury enhances filtration of liver-derived angiotensinogen and renal angiotensin II generation.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Disease Models, Animal; Exotoxins; Genotype; Kidney Diseases; Kidney Tubules, Proximal; Liver; Membrane Proteins; Mice, Knockout; Phenotype; Podocytes; RNA, Messenger; Sodium; Time Factors; Up-Regulation | 2014 |
Cardiovascular effect of angiotensin-(1-12) in the caudal ventrolateral medullary depressor area of the rat.
Topics: Adrenergic alpha-1 Receptor Agonists; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Captopril; Heart Rate; Losartan; Male; Medulla Oblongata; Nitroprusside; Peptide Fragments; Phenylephrine; Rats; Rats, Wistar; Vasomotor System | 2014 |
Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system.
Topics: Angiotensin II; Angiotensinogen; Benzimidazoles; Benzoates; Cell Hypoxia; Cell Line; Collagen Type I; Fibroblasts; Gene Expression Regulation; Humans; Imidazoles; Lung; NF-kappa B; Peptidyl-Dipeptidase A; Pyridines; Pyrrolidines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Telmisartan; Thiocarbamates | 2013 |
High glucose induces activation of the local renin‑angiotensin system in glomerular endothelial cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Diabetic Nephropathies; Endothelial Cells; Glucose; Humans; Kidney; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger | 2014 |
Kcne2 deletion creates a multisystem syndrome predisposing to sudden cardiac death.
Topics: Anemia; Angiotensin II; Angiotensinogen; Animals; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Diabetes Mellitus; Dyslipidemias; Gene Regulatory Networks; Genotype; Heterozygote; Hyperkalemia; Ischemia; Long QT Syndrome; Mice; Mice, Knockout; Potassium Channels, Voltage-Gated | 2014 |
Angiotensin II evokes angiogenic signals within skeletal muscle through co-ordinated effects on skeletal myocytes and endothelial cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Cell Line; Endothelial Cells; Extracellular Matrix; Losartan; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Microvessels; Muscle Fibers, Skeletal; Muscle, Skeletal; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Vascular Endothelial Growth Factor A | 2014 |
ROCK/NF-κB axis-dependent augmentation of angiotensinogen by angiotensin II in primary-cultured preglomerular vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Male; Muscle, Smooth, Vascular; NF-kappa B; Rats; rho-Associated Kinases; Sesquiterpenes | 2014 |
Neuronal over-expression of ACE2 protects brain from ischemia-induced damage.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Arterial Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Humans; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Renin | 2014 |
Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aldosterone; Angiotensin II; Angiotensinogen; Asian People; Biomarkers; China; Collagen Type IV; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Receptors, Angiotensin; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Young Adult | 2015 |
Uric acid induces oxidative stress via an activation of the renin-angiotensin system in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antioxidants; Captopril; Cardiovascular Diseases; Mice; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Uric Acid | 2015 |
Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.
Topics: Adaptor Proteins, Signal Transducing; Aldosterone; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Epithelial Sodium Channels; Gene Deletion; Hydrogen-Ion Concentration; Hypertension; Kidney Tubules, Distal; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Renal Reabsorption; RNA, Messenger; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Urinalysis; Vasoconstrictor Agents | 2014 |
Special deLIVERy: podocyte injury promotes renal angiotensin II generation from liver-derived angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Kidney Diseases; Kidney Tubules, Proximal; Liver; Podocytes | 2014 |
Role of intrarenal (pro)renin receptor in ischemic acute kidney injury in rats.
Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Creatinine; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Ischemia; Kidney Tubules; Male; NF-kappa B; Phosphorylation; Prorenin Receptor; Proton-Translocating ATPases; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Sodium Chloride; Tetrazoles; Vacuolar Proton-Translocating ATPases | 2015 |
Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cattle; Cell Line; Cell Nucleus; Epithelial Cells; Kidney; Peptide Fragments; Prorenin Receptor; Protease Inhibitors; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Sheep; Time Factors | 2015 |
Novel mechanism of blood pressure regulation by forkhead box class O1-mediated transcriptional control of hepatic angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cells, Cultured; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Hemodynamics; Hepatocytes; Insulin; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Renin-Angiotensin System | 2014 |
Cardiovascular dysfunction in adult mice following postnatal intermittent hypoxia.
Topics: Age Factors; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Baroreflex; Blood Pressure; Cardiovascular Diseases; DNA Methylation; Heart Rate; Hypoxia; Mice; Mice, Inbred C57BL; Renin-Angiotensin System | 2015 |
Changes in urinary angiotensinogen posttreatment in pediatric IgA nephropathy patients.
Topics: Adolescent; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Biomarkers; Biopsy; Child; Enzyme-Linked Immunosorbent Assay; Female; Glomerulonephritis, IGA; Humans; Immunohistochemistry; Kidney; Male; Predictive Value of Tests; Renin-Angiotensin System; Time Factors; Transforming Growth Factor beta; Treatment Outcome; Urinalysis | 2015 |
Up-regulation of intrarenal renin-agiotensin system contributes to renal damage in high-salt induced hypertension rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Diet; Hypertension, Renal; Kidney; Losartan; Male; Proteinuria; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary; Up-Regulation | 2014 |
Dexamethasone promotes hypertension by allele-specific regulation of the human angiotensinogen gene.
Topics: Alleles; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dexamethasone; Gene Expression; Genetic Predisposition to Disease; Glucocorticoids; Haplotypes; Humans; Hypertension; Immunoblotting; Male; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Protein Binding; Receptors, Glucocorticoid; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Superoxide Dismutase-1 | 2015 |
Vitamin D depletion aggravates hypertension and target-organ damage.
Topics: Acute-Phase Proteins; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Creatinine; Heart; Humans; Hypertension; Lipocalin-2; Lipocalins; Natriuretic Peptides; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System; Risk Factors; RNA, Messenger; Vitamin D; Vitamin D Deficiency | 2015 |
Renal nerve stimulation leads to the activation of the Na+/H+ exchanger isoform 3 via angiotensin II type I receptor.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electric Stimulation; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Male; Natriuresis; Phosphorylation; Rats, Wistar; Receptor, Angiotensin, Type 1; Renal Reabsorption; Renin-Angiotensin System; Signal Transduction; Sodium; Sodium-Hydrogen Exchanger 3; Sodium-Hydrogen Exchangers; Sympathetic Nervous System; Time Factors; Urodynamics | 2015 |
Unilateral ureteral obstruction attenuates intrarenal angiotensin II generation induced by podocyte injury.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Disease Models, Animal; Down-Regulation; Exotoxins; Female; Glomerular Filtration Rate; Humans; Interleukin-2 Receptor alpha Subunit; Kidney Diseases; Mice, Inbred C57BL; Mice, Transgenic; Podocytes; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Time Factors; Ureteral Obstruction | 2015 |
[Up-regulation of intrarenal renin-angiotensin system contributes to renal damage in high-salt induced hypertension rats].
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Male; Proteinuria; Rats; Rats, Inbred WKY; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Up-Regulation | 2015 |
Cys18-Cys137 disulfide bond in mouse angiotensinogen does not affect AngII-dependent functions in vivo.
Topics: Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Disease Models, Animal; DNA; DNA Mutational Analysis; Mice; Mutation; Renin; Renin-Angiotensin System | 2015 |
High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Body Weight; Echocardiography; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Heart Ventricles; HSP27 Heat-Shock Proteins; Hypertension; Lung; Male; Myocardium; Organ Size; p38 Mitogen-Activated Protein Kinases; Prorenin Receptor; Rats; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Signal Transduction; Sodium Chloride, Dietary; Transforming Growth Factor beta1 | 2015 |
Downregulation of the vascular renin-angiotensin system by aerobic training - focus on the balance between vasoconstrictor and vasodilator axes - .
Topics: Aerobiosis; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Femoral Artery; Kidney; Male; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin-Angiotensin System; Running; Vasoconstriction; Vasodilation | 2015 |
Angiotensin (1-7), small but complicated, needs more exercise.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Male; Peptide Fragments; Physical Conditioning, Animal; Renal Artery; Renin-Angiotensin System | 2015 |
Role of the renin-angiotensin system, renal sympathetic nerve system, and oxidative stress in chronic foot shock-induced hypertension in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Corticosterone; Cyclic N-Oxides; Denervation; Electric Stimulation; Hypertension; Male; Oxidative Stress; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Spin Labels; Sympathetic Nervous System; Thiobarbituric Acid Reactive Substances | 2015 |
Nanoparticle-mediated RNA interference of angiotensinogen decreases blood pressure and improves myocardial remodeling in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Gene Knockdown Techniques; Genetic Therapy; Hypertension; Male; Myocardium; Nanoparticles; Organ Size; Rats, Inbred SHR; RNA Interference; RNA, Messenger; RNA, Small Interfering; Transfection; Ventricular Remodeling | 2015 |
A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling.
Topics: Angiotensin II; Angiotensinogen; Animals; Calcium; Calcium Channels; Calcium Signaling; Cardiomegaly; Hemodynamics; Homeostasis; Mice, Knockout; Myocytes, Cardiac; TRPC Cation Channels; Ventricular Remodeling | 2015 |
Differential expression of the angiotensin-(1-12)/chymase axis in human atrial tissue.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensinogen; Atrial Fibrillation; Chymases; Echocardiography; Female; Gene Expression Regulation, Enzymologic; Heart Atria; Heart Valve Diseases; Humans; Male; Middle Aged; Myocardial Ischemia; RNA, Messenger; Up-Regulation; Ventricular Remodeling | 2015 |
Local Augmented Angiotensinogen Secreted from Apoptotic Vascular Endothelial Cells Is a Vital Mediator of Vascular Remodelling.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Apoptosis; Cell Line; Human Umbilical Vein Endothelial Cells; Humans; Lisinopril; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Rats; Vascular Remodeling | 2015 |
Depressor effect of chymase inhibitor in mice with high salt-induced moderate hypertension.
Topics: Albuminuria; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chymases; Disease Models, Animal; Diuretics; Heart Rate; Hypertension; Male; Mice, Inbred C57BL; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Serine Proteinase Inhibitors; Sodium Chloride, Dietary; Time Factors | 2015 |
Angiotensinogen Exerts Effects Independent of Angiotensin II.
Topics: Amides; Amino Acid Sequence; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Conserved Sequence; Dependovirus; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Fumarates; Genetic Vectors; Genotype; Hepatocytes; Hypertension; Liver; Male; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; Oligonucleotides, Antisense; Phenotype; Protein Binding; Protein Interaction Domains and Motifs; Receptors, LDL; Renin; Signal Transduction; Time Factors; Transduction, Genetic; Weight Gain | 2016 |
Transient Exposure of Enalapril Normalizes Prenatal Programming of Hypertension and Urinary Angiotensinogen Excretion.
Topics: Albuminuria; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Enalapril; Female; Hypertension; Kidney; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2015 |
Augmented circadian rhythm of the intrarenal renin-angiotensin systems in anti-thymocyte serum nephritis rats.
Topics: Angiotensin II; Angiotensinogen; Animals; Antilymphocyte Serum; Circadian Rhythm; Disease Models, Animal; Hydralazine; Kidney; Lymphocytes; Male; Nephritis; Olmesartan Medoxomil; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Possible role for nephron-derived angiotensinogen in angiotensin-II dependent hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nephrons; Sodium, Dietary | 2016 |
Atrial natriuretic peptide attenuation of renal ischemia-reperfusion injury after major surgery.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Angiotensin II; Angiotensinogen; Animals; Atrial Natriuretic Factor; Kidney; Lipocalin-2; Lipocalins; Male; Mitochondria; Oxygen Consumption; Postoperative Complications; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Reperfusion Injury | 2016 |
Augmentation of angiotensinogen expression in the proximal tubule by intracellular angiotensin II via AT1a/MAPK/NF-кB signaling pathways.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Kidney Tubules, Proximal; Male; MAP Kinase Signaling System; NF-kappa B; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Sodium | 2016 |
Free Fatty Acids Activate Renin-Angiotensin System in 3T3-L1 Adipocytes through Nuclear Factor-kappa B Pathway.
Topics: 3T3-L1 Cells; Adipocytes; alpha-2-HS-Glycoprotein; Angiotensin II; Angiotensinogen; Animals; Mice; NF-kappa B; Palmitic Acid; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Intrarenal Renin-Angiotensin System: Locally Synthesized or Taken up Via Endocytosis?
Topics: Angiotensin II; Angiotensinogen; Endocytosis; Humans; Kidney; Renin; Renin-Angiotensin System | 2016 |
Hypertensive retinopathy in a transgenic angiotensin-based model.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Hypertensive Retinopathy; Male; Rats, Transgenic; Renin; Renin-Angiotensin System | 2016 |
Regulation of angiotensinogen expression by angiotensin II in spontaneously hypertensive rat primary astrocyte cultures.
Topics: Angiotensin II; Angiotensinogen; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Down-Regulation; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; RNA, Messenger; Up-Regulation | 2016 |
The locally activated renin-angiotensin system is involved in albumin permeability in glomerular endothelial cells under high glucose conditions.
Topics: Albumins; Angiotensin II; Angiotensinogen; Animals; Cell Membrane Permeability; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelial Cells; Glucose; Humans; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sweetening Agents | 2017 |
Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Chymases; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR | 2016 |
Low dose ouabain stimulates NaK ATPase α1 subunit association with angiotensin II type 1 receptor in renal proximal tubule cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Hypertension; Kidney Tubules, Proximal; Mice; Ouabain; Peptidyl-Dipeptidase A; Phosphorylation; Protein Binding; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Transfection | 2016 |
Overexpression of Intrarenal Renin-Angiotensin System in Human Acute Tubular Necrosis.
Topics: Adult; Albumins; Angiotensin II; Angiotensinogen; Female; Humans; Kidney Tubular Necrosis, Acute; Kidney Tubules; Male; Middle Aged; Renin-Angiotensin System; Severity of Illness Index; Up-Regulation | 2016 |
Intrarenal renin-angiotensin system activation in end-stage renal disease.
Topics: Angiotensin II; Angiotensinogen; Humans; Kidney; Kidney Failure, Chronic; Renin; Renin-Angiotensin System | 2017 |
Brain Renin-Angiotensin System: Does It Exist?
Topics: Amides; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Desoxycorticosterone Acetate; Disease Models, Animal; Fumarates; Hypertension; Mice; Mice, Knockout; Random Allocation; Rats; Rats, Inbred SHR; Reference Values; Renin-Angiotensin System | 2017 |
Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cerebral Ventricles; Genotype; Humans; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Renin; Renin-Angiotensin System; Subfornical Organ; Time Factors; Up-Regulation | 2017 |
NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Chlorogenic Acid; Commiphora; Curcumin; Diet, High-Fat; Dietary Supplements; Fatty Acid-Binding Proteins; Gene Expression Regulation; Inulin; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Non-alcoholic Fatty Liver Disease; Plant Extracts; Plant Gums; RNA, Messenger; Silymarin; Suppressor of Cytokine Signaling 3 Protein | 2017 |
Arsenite Induces Vascular Endothelial Cell Dysfunction by Activating IRE1α/XBP1s/HIF1α-Dependent ANGII Signaling.
Topics: Angiotensin II; Angiotensinogen; Arsenites; Cells, Cultured; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Endoribonucleases; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Oxidative Stress; Peptidyl-Dipeptidase A; Protein Serine-Threonine Kinases; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Sodium Compounds; Time Factors; Transcription, Genetic; Unfolded Protein Response; Water Pollutants, Chemical; X-Box Binding Protein 1 | 2017 |
ALDH2 protects against alcoholic cardiomyopathy through a mechanism involving the p38 MAPK/CREB pathway and local renin-angiotensin system inhibition in cardiomyocytes.
Topics: Adenoviridae; Aldehyde Dehydrogenase, Mitochondrial; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Cardiomyopathy, Alcoholic; Cardiotonic Agents; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Genetic Vectors; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Rats; Rats, Wistar; Renin-Angiotensin System | 2018 |
Effect of a SGLT2 inhibitor on the systemic and intrarenal renin-angiotensin system in subtotally nephrectomized rats.
Topics: Administration, Oral; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Glucosides; Glycosuria; Indoles; Kidney; Male; Nephrectomy; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Renin; Renin-Angiotensin System; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
The Intrarenal Renin-angiotensin System Is Activated Immediately after Kidney Donation in Kidney Transplant Donors.
Topics: Aged; Angiotensin II; Angiotensinogen; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Glomerular Filtration Rate; Humans; Kidney Transplantation; Male; Middle Aged; Postoperative Period; Renin-Angiotensin System; Tissue and Organ Harvesting; Tissue Donors | 2019 |
Development and application of low-cost T-ARMS-PCR assay for AGT and CYP11B1 gene polymorphisms.
Topics: Alleles; Angiotensin II; Angiotensinogen; Blood Pressure; Cardiovascular Diseases; Female; Gene Frequency; Genotype; Genotyping Techniques; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Renin-Angiotensin System; Steroid 11-beta-Hydroxylase | 2019 |
Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin-angiotensin system.
Topics: Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Female; Kidney; Liver; Losartan; Mice; Mice, Inbred C57BL; Prorenin Receptor; Receptors, Cell Surface; Renin-Angiotensin System; Vasopressins | 2019 |
Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis-Brief Report.
Topics: Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Female; Hypercholesterolemia; Low Density Lipoprotein Receptor-Related Protein-2; Male; Mice; Mice, Inbred C57BL; Oligonucleotides, Antisense; Renin-Angiotensin System | 2019 |
Wnt/β-catenin regulates blood pressure and kidney injury in rats.
Topics: Albuminuria; Angiotensin II; Angiotensinogen; Animals; beta Catenin; Blood Pressure; Blood Urea Nitrogen; Bridged Bicyclo Compounds, Heterocyclic; Collagen Type I; Creatinine; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Fibronectins; Gene Expression Regulation; Hypertension; Kidney; Male; Nephrectomy; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Pyrimidinones; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Wnt Proteins; Wnt Signaling Pathway | 2019 |
Maternal separation-induced increases in vascular stiffness are independent of circulating angiotensinogen levels.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet, High-Fat; Male; Maternal Deprivation; Rats; Rats, Inbred WKY; Vascular Stiffness | 2020 |
Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice-Brief Report.
Topics: Amino Acid Substitution; Angiotensin II; Angiotensinogen; Animals; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hepatocytes; Humans; Hypertension; Male; Mice, Knockout; Plaque, Atherosclerotic; Receptors, LDL; Renin; Species Specificity | 2020 |
No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Brain; Brain Stem; Desoxycorticosterone Acetate; Hypertension; Male; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Valsartan | 2021 |
Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells.
Topics: Angiotensin II; Angiotensinogen; Animals; Aorta; Gene Expression Regulation, Developmental; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukocyte Common Antigens; Mice; Peptides; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; Signal Transduction; Stem Cells | 2021 |
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.
Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Arterial Pressure; Captopril; Disease Models, Animal; Kidney; Liver; Losartan; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Small Interfering | 2021 |
Newly developed radioimmunoassay for Human Angiotensin-(1-12) measurements in plasma and urine.
Topics: Aged; Angiotensin II; Angiotensinogen; Antibodies; Antihypertensive Agents; Blood Pressure; Case-Control Studies; Chymases; Female; Gene Expression Regulation; Humans; Hypertension; Limit of Detection; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Recombinant Proteins; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Revisiting the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chymases; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Peptide Fragments; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Loss of Hepatic Angiotensinogen Attenuates Sepsis-Induced Myocardial Dysfunction.
Topics: Angiotensin II; Angiotensinogen; Animals; Heart Failure; Liver; Low Density Lipoprotein Receptor-Related Protein-1; Mice; Myocardium; NLR Family, Pyrin Domain-Containing 3 Protein; Sepsis | 2021 |
Vitamin D suppresses bleomycin-induced pulmonary fibrosis by targeting the local renin-angiotensin system in the lung.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Bleomycin; Disease Models, Animal; Ergocalciferols; Losartan; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Pulmonary Fibrosis; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Transforming Growth Factor beta; Vitamin D | 2021 |
Angiotensinogen Takes Some of the Spotlight From Angiotensin II in the Cardiohepatic Axis.
Topics: Angiotensin II; Angiotensinogen; Renin; Renin-Angiotensin System | 2021 |
Angiotensin II-induced renal angiotensinogen formation is enhanced in mice lacking tumor necrosis factor-alpha type 1 receptor.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension, Renal; Kidney; Male; Mice; Mice, Inbred C57BL; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Sodium Chloride, Dietary | 2021 |
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Blood Pressure; Female; Humans; Hypertension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2022 |
Conventional Vasopressor and Vasopressor-Sparing Strategies to Counteract the Blood Pressure-Lowering Effect of Small Interfering RNA Targeting Angiotensinogen.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Fludrocortisone; Hypertension; Mice; Midodrine; Norepinephrine; Rats; Renin; Renin-Angiotensin System; RNA, Small Interfering; Vasoconstrictor Agents | 2022 |
Immunosuppression by Mycophenolate Mofetil Mitigates Intrarenal Angiotensinogen Augmentation in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Immunosuppression Therapy; Kidney; Kidney Diseases; Mycophenolic Acid; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2022 |
Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice-Brief Report.
Topics: Aminopropionitrile; Angiotensin II; Angiotensinogen; Animals; Aortic Aneurysm, Thoracic; Aortic Rupture; Dilatation, Pathologic; Disease Models, Animal; Irbesartan; Losartan; Lysine; Male; Mice; Mice, Inbred C57BL; Protein-Lysine 6-Oxidase; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2022 |
LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling.
Topics: Angiotensin II; Angiotensinogen; Animals; Female; Losartan; Low Density Lipoprotein Receptor-Related Protein-1; Male; Mesenteric Artery, Superior; Mice; Signal Transduction | 2023 |
Angiotensin deficient FVB/N mice are normotensive.
Topics: Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Mice; Mice, Inbred Strains; Nitric Oxide; Renin-Angiotensin System | 2023 |
Intrarenal renin-angiotensin system activation and macrophage infiltrations in pediatric chronic glomerulonephritis.
Topics: Angiotensin II; Angiotensinogen; Chemokine CCL2; Child; Chronic Disease; Glomerulonephritis; Humans; Immunosuppressive Agents; Kidney; Macrophages; Renin-Angiotensin System | 2023 |
Pathologic HDAC1/c-Myc signaling axis is responsible for angiotensinogen transcription and hypertension induced by high-fat diet.
Topics: Angiotensin II; Angiotensinogen; Animals; Diet, High-Fat; Hypertension; Male; Mice; Mice, Inbred C57BL; Obesity; Proto-Oncogene Proteins c-myc; Signal Transduction | 2023 |
Sodium appetite and thirst do not require angiotensinogen production in astrocytes or hepatocytes.
Topics: Angiotensin II; Angiotensinogen; Animals; Appetite; Astrocytes; Hepatocytes; Hypovolemia; Mice; Sodium; Sodium Chloride; Thirst; Water | 2023 |
Angiotensinogen, Angiotensin-Converting Enzyme, and Chymase Gene Polymorphisms as Biomarkers for Basal Cell Carcinoma Susceptibility.
Topics: Angiotensin II; Angiotensinogen; Biomarkers; Carcinoma, Basal Cell; Chymases; DNA; Genotype; Humans; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin-Angiotensin System; Serine Proteases; Skin Neoplasms | 2023 |
Vasoactive mediators of hypertension in obesity.
Topics: Adult; Aldosterone; Angiotensin II; Angiotensinogen; Blood Pressure; Cross-Sectional Studies; Humans; Hypertension; Male; Neprilysin; Obesity, Morbid; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Vasodilator Agents | 2023 |
Megalin is involved in angiotensinogen-induced, angiotensin II-mediated ERK1/2 signaling to activate Na + -H + exchanger 3 in proximal tubules.
Topics: Angiotensin II; Angiotensinogen; Animals; Kidney Tubules, Proximal; Low Density Lipoprotein Receptor-Related Protein-2; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Sodium; Sodium-Hydrogen Exchanger 3 | 2023 |