angiotensin ii has been researched along with angiotensin ii, des-phe(8)- in 706 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (0.57) | 18.7374 |
| 1990's | 105 (14.87) | 18.2507 |
| 2000's | 182 (25.78) | 29.6817 |
| 2010's | 327 (46.32) | 24.3611 |
| 2020's | 88 (12.46) | 2.80 |
| Authors | Studies |
|---|---|
| Brosnihan, KB; DiCorleto, PE; Ferrario, CM; Jacobsen, DW; Santos, RA | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Yamamoto, K | 1 |
| Baracho, NC; Santos, RA | 1 |
| Diz, DI; Pirro, NT | 1 |
| Braszko, J; Hoły, Z; Kupryszewski, G; Wiśniewski, K; Witczuk, B | 1 |
| Andries, M; Denef, C; Robberecht, W | 1 |
| Campbell, DJ; Clark, IJ; Lawrence, AC | 1 |
| Jarrott, B; Krstew, E; Widdop, RE | 1 |
| Batista, EN; Campagnole-Santos, MJ; Heringer, SB; Khosla, MC; Santos, RA | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Greene, LJ; Santos, RA; Welches, WR | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Khosla, MC; Kohara, K | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Tallant, EA | 1 |
| Brosnihan, KB; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Milsted, A; Tallant, EA | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Tallant, EA | 1 |
| Barnes, KL; Felix, D; Ferrario, CM; Imboden, H; Khosla, MC; Montani, B | 1 |
| Ferrario, C; Fouad-Tarazi, FM; Khosla, M; Kumagai, H | 1 |
| Campagnole-Santos, MJ; Diz, DI; Ferrario, CM | 1 |
| Barnes, KL; Ferrario, CM; Knowles, WD | 1 |
| Ferrario, CM; Khosla, MC; Meixner, K; Trachte, GJ | 1 |
| Barnes, KL; Block, CH; Brosnihan, KB; Diz, DI; Ferrario, CM; Khosla, MC; Santos, RA | 1 |
| Brosnihan, KB; Campagnole-Santos, MJ; Diz, DI; Ferrario, CM; Khosla, MC; Santos, RA | 1 |
| Brosnihan, KB; Chappell, MC; Diz, DI; Ferrario, CM | 1 |
| Brosnihan, KB; Ferrario, CM; Khosla, MC; Santos, RA; Schiavone, MT | 1 |
| Imura, H; Khosla, MC; Kono, T; Oseko, F; Taniguchi, A | 1 |
| Benter, IF; Diz, DI; Ferrario, CM | 1 |
| Khosla, MC; Lima, CV; Paula, RD; Santos, RA | 1 |
| Dean, RH; Ferrario, CM; Fuller, SB; Nakamoto, H; Robaczewski, DL; Winicov, E | 1 |
| Smith, RD | 1 |
| Hintze, TH; Nasjletti, A; Seyedi, N; Xu, X | 1 |
| Benter, IF; Diz, DI; Ferrario, CM; Morris, M | 1 |
| Absher, DR; Rowe, BP; Saylor, DL; Speth, RC | 1 |
| Block, CH; Calka, J | 1 |
| Ahima, RS; Kadowitz, PJ; Khosla, MC; Minkes, RK; Osei, SY; Weaver, JP | 1 |
| Brosnihan, B; Bunnemann, B; Cintra, A; Ganten, D; Hasselrot, U; Hilgenfeldt, U; Lippoldt, A; Metzger, R; Rosén, L; Ueki, A | 1 |
| Carr, RD; Henderson, IW; Mahon, JM; Nicol, AK | 1 |
| Bell-Quilley, CP; Hilchey, SD | 1 |
| Ferrario, CM; Ganten, D; Matsumura, K; Moriguchi, A; Reilly, TM; Tallant, EA; Walton, H | 1 |
| Garcia, NH; Garvin, JL | 1 |
| Ambühl, P; Felix, D; Khosla, MC | 1 |
| Baracho, NC; Caligiorne, SM; Campagnole-Santos, MJ; Fontes, MA; Gropen Júnior, C; Neves, LA; Oliveira, DR; Rodrigues, AR; Santos, RA; Silva, LC | 1 |
| Busse, R; Hecker, M | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Guertzenstein, PG; Khosla, MC; Santos, RA; Silva, LC | 1 |
| Block, CH; Botelho, LM; Khosla, MC; Santos, RA | 1 |
| Brosnihan, KB; Ferrario, CM; Ganten, D; Kumagai, H; Moriguchi, A; Senanayake, PD | 1 |
| Cheng, DY; Dent, EL; DeWitt, BJ; Kadowitz, PJ; Nossaman, BD | 1 |
| Bell-Quilley, CP; DelliPizzi, AM; Hilchey, SD | 1 |
| Bara, AT; Busse, R; Hecker, M; Pörsti, I | 1 |
| Campagnole-Santos, MJ; Santos, RA | 1 |
| Adler-Graschinsky, E; Enero, MA; Gironacci, MM; Peña, C | 1 |
| Campagnole-Santos, MJ; Campos, RR; Fontes, MA; Guertzenstein, PG; Khosla, MC; Santos, RA; Silva, LC | 1 |
| Busija, DW; Meng, W | 1 |
| Andreatta-van Leyen, S; Douglas, JG; Khosla, MC; Romero, MF | 1 |
| Cooney, AS; Fitzsimons, JT | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Jaiswal, RK; Tallant, EA | 1 |
| Campbell, DJ; Duncan, AM; Harrap, SB; Kladis, A | 1 |
| Batlle, D; Flores, G; Ye, M | 1 |
| Brosnihan, KB; Ferrario, CM; Li, P | 1 |
| Baracho, NC; Cesar, KR; Khosla, MC; Magaldi, AJ; Passaglio, KT; Santos, RA; Simões e Silva, AC | 1 |
| Allen, M; Fitzsimons, JT; Herbert, J; Mahon, JM | 1 |
| Chisolm, GM; Ferrario, CM; Freeman, EJ; Tallant, EA | 1 |
| Diz, DI; Ferrario, CM | 1 |
| Ferrario, CM; Handa, RK; Strandhoy, JW | 1 |
| Brosnihan, KB; Fernandez, C; Ferrario, CM; Luque, M; Martell, N; Martin, P | 1 |
| Botelho, LM; Carvalho, AC; Greene, LJ; Santos, RA | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Khosla, MC; Lima, DX; Oliveira, RC; Santos, RA | 1 |
| Berglund, L; Reneland, R | 1 |
| Chappell, MC; Ferrario, CM; Lu, X; Tallant, EA; Weiss, RB | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Li, P | 1 |
| Bosch, SM; Diz, DI; Falgui, B; Ferrario, CM; Ganten, D; Kent, J; Westwood, BM | 1 |
| Higson, JT; Tallant, EA | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Khosla, MC; Lopes, OU; Martins Pinge, MC; Naves, V; Santos, RA | 1 |
| Adler-Graschinsky, E; Gironacci, MM; Lorenzo, PS | 1 |
| Abbas, A; Carbini, LA; Gorelik, G; Scicli, AG | 1 |
| Brosnihan, KB; Chappell, MC; Diz, DI; Ferrario, CM; Tallant, EA | 1 |
| Khosla, MC; Lima, CV; Paula, RD; Resende, FL; Santos, RA | 1 |
| Britto, RR; Campagnole-Santos, MJ; Fagundes-Moura, CR; Khosla, MC; Santos, RA | 1 |
| Forster, C; le Tran, Y | 1 |
| Heyne, N; Osswald, H; Richter, K; Vallon, V | 1 |
| Benter, IF; Harper, JL; Malik, KU; Muthalif, MM; Uddin, MR | 1 |
| Brosnihan, KB; Ferrario, CM; Ganten, D; Li, P | 1 |
| Chappell, MC; Ferrario, CM; Iyer, SN | 1 |
| Chappell, MC; Ferrario, CM; Pirro, NT; Sykes, A | 1 |
| Averill, DB; Chappell, MC; Diz, DI; Ferrario, CM; Iyer, SN | 1 |
| Brosnihan, KB; Chappell, MC; Dean, RH; Fernandez, A; Ferrario, CM; Flack, JM; Luque, M; Martell, N; Novikov, SV; Pinillas, C; Yunis, C | 1 |
| Deddish, PA; Erdös, EG; Jackman, HL; Marcic, B; Skidgel, RA; Wang, HZ | 1 |
| Carbini, LA; Gorelik, G; Scicli, AG | 1 |
| Ferrario, CM; Friedman, DP; Krob, HA; Vinsant, SL | 1 |
| Fechter, K; Heyne, N; Khosla, MC; Richter, K; Vallon, V | 1 |
| Baracho, NC; Bello, AP; Khosla, MC; Santos, RA; Simões e Silva, AC | 1 |
| Chappell, MC; Ferrario, CM; Ganten, D; Iyer, SN; Yamada, K | 1 |
| Gironacci, M; López Ordieres, MG; Peña, C; Rodríguez de Lores Arnaiz, G | 1 |
| Brosnihan, KB; Ferrario, CM; Li, P; Tallant, EA | 1 |
| Chappell, MC; Diz, DI; Ferrario, CM; Yunis, C | 1 |
| Brosnihan, KB | 1 |
| Bomtempo, CA; Campagnole-Santos, MJ; Santos, GF; Santos, RA | 1 |
| Chappell, MC; Diz, DI; Ferrario, CM; Iyer, SN | 1 |
| Baracho, NC; Khosla, MC; Santos, RA; Simões-e-Silva, AC | 1 |
| Ferrario, CM; Iyer, SN | 1 |
| Ferrario, CM; Strawn, WB; Tallant, EA | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Fukuhara, M; Iyer, SN; Yamada, K | 1 |
| Handa, RK | 1 |
| Buikema, H; de Zeeuw, D; Henning, RH; Pinto, YM; Roks, AJ; van Geel, PP; van Gilst, WH | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Khosla, MC; Lima, DX; Santos, RA | 1 |
| Davie, AP; McMurray, JJ | 1 |
| Diz, DI; Ferrario, CM; Tallant, EA | 1 |
| Jarrott, B; Sampey, DB; Widdop, RE | 1 |
| Coba, MP; Gironacci, MM; Peña, C | 1 |
| De Carvalho, MH; Fortes, ZB; Kosla, MC; Oliveira, MA; Santos, RA | 1 |
| Dixon, B; Rowe, BP | 1 |
| Andrade, SP; Machado, RD; Santos, RA | 2 |
| Linz, W; Malinski, T; Schölkens, BA; Wiemer, G; Wohlfart, P | 1 |
| Cervenka, L; Heller, J; Horácek, V; Kramer, HJ; Malý, J | 1 |
| Ashino, K; Gotoh, E; Ishii, M; Masumori-Maemoto, S; Nagahara, T; Ueda, S; Umemura, S | 1 |
| Andrade, SP; Campagnole-Santos, MJ; Santos, RA | 1 |
| Coviello, A; Jerez, S; Peral de Bruno, M; Santos, JC | 1 |
| Allred, AJ; Averill, DB; Chappell, MC; Ferrario, CM; Iyer, SN; Yamada, K | 1 |
| Bader, M; Baltatu, O; Caligiorne, SM; Campagnole-Santos, MJ; Fontes, MA; Ganten, D; Santos, RA | 1 |
| Allred, AJ; Chappell, MC; Diz, DI; Ferrario, CM | 1 |
| Min, L; Sim, MK; Xu, XG | 1 |
| Fernandez, BE; Gironacci, MM; Peña, C; Rodríguez-Fermepín, M; Rubio, M; Vatta, M | 1 |
| Caligiorne, SM; Campagnole-Santos, MJ; Chaves, GZ; Khosla, MC; Santos, RA | 1 |
| Campbell, DJ; Moritz, KM; Wintour, EM | 1 |
| Catelli De Carvalho, MH; Fernandes, L; Fortes, ZB; Nigro, D; Santos, RA; Tostes, RC | 1 |
| Ardaillou, R; Chansel, D; Curat, C; Oko, A; Vandermeersch, S | 1 |
| Clark, MA; Diz, DI; Tallant, EA | 2 |
| Ihara, H; Nagai, N; Napiorkowska-Pawlak, D; Pawlak, R; Takada, A; Takada, Y; Urano, T | 1 |
| Bader, M; Passaglio, KT; Pesquero, JB; Simões E Silva, AC; Souza Dos Santos, RA | 1 |
| Almeida, AP; Ferreira, AJ; Santos, RA | 1 |
| Brosnihan, KB; Ishii, M; Masumori-Maemoto, S; Ueda, S; Umemura, S; Wada, A | 1 |
| Arima, S; Ito, S | 1 |
| Bica, RB; Caruso-Neves, C; Correa, JS; Lara, LS; Lopes, AG; Marques-Fernandes, MF; Sena, SL | 1 |
| Bradley, WE; Brosnihan, KB; Dell'Italia, LJ; Farrell, DM; Ferrario, CM; Jaffa, AA; Wei, CC | 1 |
| Borges, EL; Braga, AA; Cabral, BM; Neves, MJ; Rogana, E; Santos, RA | 1 |
| Bayorh, MA; Eatman, D; Emmett, N; Socci, RR; Thierry-Palmer, M; Walton, M | 1 |
| Berrios, C; Brosnihan, KB; Corthorn, J; Ferrario, CM; Foradori, AC; Germain, AM; Valdés, G | 1 |
| Baggerman, G; Broeck, JV; Le, MT; Vanderheyden, PM; Vauquelin, G | 1 |
| Carretero, OA; Garvin, JL; Ren, Y | 1 |
| diZerega, GS; Rodgers, KE; Xiong, S | 1 |
| Braga, AN; da Silva Lemos, M; da Silva, JR; dos Santos, RA; Fontes, WR | 1 |
| Bader, M; Baltatu, O; Campagnole-Santos, MJ; Couto, AS; Ganten, D; Santos, RA | 1 |
| Tangelder, GJ; Ter Wee, PM; van Lambalgen, TA; van Rodijnen, WF; van Wijhe, MH | 1 |
| Naito, Y; Takada, A; Takada, Y; Urano, T; Yoshida, M | 1 |
| Averill, DB; Brosnihan, KB; Chappell, MC; Dean, RH; Diz, DI; Ferrario, CM; Iskandar, SS | 1 |
| Alzamora, AC; Campagnole-Santos, MJ; Santos, RA | 2 |
| Liu, D; Tepel, M; Van Der Giet, M; Zhong, J; Zhu, S; Zhu, Z | 1 |
| Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R | 1 |
| Bürgelová, M; Cervenka, L; Heller, J; Kramer, HJ; Malý, J; Teplan, V; Velicková, G; Vítko, S | 1 |
| Brosnihan, KB; Chen, K; Ferrario, CM; Karoly, M; Merrill, DC | 1 |
| Nascimento, AA; Sampaio, WO; Santos, RA | 1 |
| Dupont, A; Ebinger, G; Michotte, Y; Sarre, S; Smolders, I; Vanderheyden, P; Vauquelin, G | 1 |
| diZerega, G; Espinoza, T; Felix, J; Maldonado, S; Roda, N; Rodgers, KE | 1 |
| Campagnole-Santos, MJ; Guerra, MT; Haibara, AS; Khosla, MC; Leite, MF; Lemos, VS; Paula, RD; Pinheiro, SV; Santos, RA; Silva, DM; Simões e Silva, AC | 1 |
| DiZerega, GS; Rodgers, K; Xiong, S | 1 |
| Costa, AP; Dos Reis, AM; Fagundes-Moura, CR; Pereira, VM; Santos, RA; Silva, LF; Vieira, MA | 1 |
| Bild, W; Boisteanu, CP; Haulica, I; Ionita, T; Mihaila, CN; Neagu, B | 1 |
| Oberhauser, V; Rump, LC; Stegbauer, J; Vonend, O | 2 |
| Bie, P; Plovsing, RR; Sandgaard, NC; Wamberg, C | 1 |
| Bie, P; Hoilund-Carlsen, PF; Holstein-Rathlou, NH; Plovsing, RR; Sandgaard, NC; Simonsen, JA; Wamberg, C | 1 |
| Averill, DB; Brosnihan, KB; Chappell, MC; Ferrario, CM; Joyner, J; Neves, LA; Penninger, J; Sarao, R | 1 |
| Clark, MA; Tallant, EA | 1 |
| Chiong, M; Godoy, I; Jalil, JE; Lavandero, S; Ocaranza, MP; Palomera, C; Román, M | 1 |
| Bristow, MR; Canver, CC; Meixell, GE; Zisman, LS | 1 |
| Bristow, MR; Canver, CC; Keller, RS; Lin, Q; Speth, R; Weaver, B; Zisman, LS | 1 |
| Cesar, KR; de Araújo, M; Magaldi, AJ; Santos, RA; Simões e Silva, AC | 1 |
| Dobruch, J; Khosla, MC; Paczwa, P; Szczepańska-Sadowska, E; Łoń, S | 1 |
| Collister, JP; Hendel, MD | 1 |
| Behnia, R; Garber, S; Igić, R; Sekosan, M; Urbanska, RA | 1 |
| Correia, ML; de Carvalho, LC; Emiliano, AF; Mendes-Ribeiro, AC; Resende, AC; Soares de Moura, R; Tano, T | 1 |
| Gironacci, MM; Gorzalczany, S; Peña, C; Taira, C; Yujnovsky, I | 1 |
| Bernstein, KE; Brosnihan, KB; Chappell, MC; Gallagher, PE; Kramer, GL; Modrall, JG; Sadjadi, J; Yu, CH | 1 |
| Averill, DB; Brosnihan, KB; Ferrario, CM; Gallagher, PE; Ishiyama, Y; Tallant, EA | 1 |
| Campagnole-Santos, MJ; de Carvalho, MH; Fernandes, L; Maia, LG; Ramos, MC; Souza dos Santos, RA | 1 |
| Burke-Wolin, T; Du, L; Li, X; Oeckler, R; Olson, S; Traganos, F; Zhao, X | 1 |
| Abi-Abib, R; Cardozo, FP; Caruso-Neves, C; De Souza, AM; Fernandes, MS; Fossari, RN; Lopes, AG; Miguel, NC; Pizzino, CP; Santos, DP | 1 |
| Diniz, JS; Regueira Filho, A; Santos, RA; Simões E Silva, AC | 1 |
| Grant, PJ; Hooper, NM; Rice, GI; Thomas, DA; Turner, AJ | 1 |
| Campbell, DJ; Esler, MD; Horowitz, JD; Zeitz, CJ | 1 |
| Burns, KD; Cheng, K; Li, N; Wilkins, JA; Zimpelmann, J | 1 |
| Chappell, MC; Ferrario, CM | 1 |
| Ferreira, AJ; Mendes, AC; Pinheiro, SV; Santos, RA | 1 |
| de Zeeuw, D; Henning, RH; Nijholt, J; Roks, AJ; van Buiten, A; van Gilst, WH | 1 |
| Ecarnot-Laubriet, A; Oudot, A; Rochette, L; Vergely, C | 1 |
| Reudelhuber, TL | 1 |
| Boomsma, F; de Jong, PE; Kocks, MJ; Lely, AT; Navis, G | 1 |
| Bürgelová, M; Cervenka, L; Kramer, HJ; Teplan, V; Thumová, M | 1 |
| Becker, LK; Campagnole-Santos, MJ; Santos, RA | 1 |
| Ferrario, CM; Gallagher, PE; Geary, RL; Igase, M; Strawn, WB | 1 |
| Cai, YM; He, JG; Liao, XX; Liu, J; Ma, H; Wang, LC; Wang, LJ; Zeng, WT | 2 |
| Averill, DB; Brosnihan, KB; Chappell, MC; Diz, DI; Ferrario, CM; Gallagher, PE; Jessup, J; Tallant, EA | 1 |
| Fontes, MA; Santos, RA; Silva, AQ | 1 |
| Duarte, FV; Faria-Silva, R; Santos, RA | 1 |
| Ebinger, G; Hristova, I; Michotte, Y; Sarre, S; Stragier, B | 1 |
| Alenina, N; Bader, M; Lemos, VS; Santos, RA; Silva, DM; Walther, T | 1 |
| Alenina, N; Almeida, AP; Bader, M; Castro, CH; Ferreira, AJ; Santos, RA | 2 |
| Campbell, DJ; Chirkov, YY; Horowitz, JD; Rajendran, S | 1 |
| Wilkinson-Berka, JL | 1 |
| Chappell, MC; Ferrario, CM; Gallagher, PE; Tallant, EA | 1 |
| Ann Tallant, E; Averill, DB; Brosnihan, KB; Chappell, MC; Ferrario, CM; Gallagher, PE; Jessup, J; Smith, RD | 1 |
| Bargetto, J; Jalil, JE; Lavandero, S; Ocaranza, MP; Palomera, C; Román, M | 1 |
| Ciobanu, A; Costuleanu, M; Gurzu, B; Petrescu, G; Slatineanu, SM | 1 |
| Boomsma, F; de Zeeuw, D; Deelman, LE; Henning, RH; Roks, AJ; van der Wouden, EA | 1 |
| Merino, M; Naftolin, F; Nemeth, G; Pepperell, JR; Yamada, Y | 1 |
| Coffman, TM; Cunha, TS; Elased, KM; Gurley, SB; Morris, M | 1 |
| Burns, KD; Su, Z; Zimpelmann, J | 1 |
| Chappel, MC; Ferrario, CM | 1 |
| Averill, DB; Chappell, MC; Diz, DI; Ferrario, CM; Figueroa, JP; Rose, JC; Shaltout, HA; Westwood, BM | 1 |
| Castro, P; Collantes, P; Copaja, M; Diaz-Araya, G; Godoy, I; Jalil, JE; Lavandero, S; Ocaranza, MP; Pinto, M; Ramirez, C; Roman, M; Varas, M | 1 |
| de Zeeuw, D; Deelman, LE; Henning, RH; Ochodnický, P; Roks, AJ; van der Wouden, EA; van Dokkum, RP | 1 |
| Campbell, WB; Hanke, CJ; Holmes, BB; Nithipatikom, K; Xu, Y | 1 |
| Diniz, JS; Pereira, RM; Pinheiro, SV; Santos, RA; Simões e Silva, AC | 1 |
| Aranda, FJ; Aranda, P; Ferrario, CM; Gaitan, MJ; Mayor-Olea, A; Morcillo, L; Reyes-Engel, A; Ruiz, M | 1 |
| Bolton, TA; Grobe, JL; Katovich, MJ; Lingis, M; Machado, JM; Mecca, AP; Raizada, MK; Shenoy, V; Speth, RC | 1 |
| Campagnole-Santos, MJ; Cortes, SF; Lemos, VS; Santos, RA; Silva, DM; Vianna, HR | 1 |
| Barcelos, LS; Collares, GB; Costa, LP; da Costa Dias, FL; Dos Santos, RA; Leite, VH; Pereira, RM; Simões e Silva, AC; Teixeira, MM | 1 |
| Baber, SR; Fokin, A; Greco, AJ; Kadowitz, PJ; Master, RG | 1 |
| Cabral, AC; Drumond, TC; Freire, CM; Machado, LJ; Nogueira, AI; Ribeiro-Oliveira, A; Simões E Silva, AC; Souza Santos, RA; Vieira, RL | 1 |
| Averill, DB; Chappell, MC; Ferrario, CM; Ganten, D; Trask, AJ | 1 |
| Achike, FI; Dharmani, M; Mustafa, MR; Sim, MK | 1 |
| Agata, J; Hyakkoku, M; Sasaki, H; Shimamoto, K; Shinshi, Y; Taniguchi, S; Ura, N; Yoshida, H | 1 |
| Campagnole-Santos, MJ; Ferreira, PM; Souza Dos Santos, RA | 1 |
| Bartoli, F; Brosnihan, KB; Cerinic, MM; Cinelli, M; Ferrario, CM; Fiori, G; Generini, S; Guiducci, S; Livi, R; Perfetto, F; Pignone, A; Rogai, V; Rosso, AD; Tempestini, A | 1 |
| Cabral, AC; Kalapothakis, E; Santos, RA; Velloso, EP; Vieira, R | 1 |
| Arthur, JM; Bland, AM; Janech, MG; Raymond, JR; Velez, JC | 1 |
| Moeller, JF; Simoni, G; Simoni, J; Tsikouris, JP; Wesson, DE | 1 |
| Casarini, DE; Irigoyen, MC; Ronchi, FA | 1 |
| Dominici, FP; Giani, JF; Gironacci, MM; Muñoz, MC; Peña, C; Turyn, D | 1 |
| Chlopicki, S; Fedorowicz, A; Kozlovski, VI; Lomnicka, M | 1 |
| Gironacci, MM; Peña, C; Polizio, AH; Tomaro, ML | 1 |
| Drazba, J; Hollyfield, JG; Karnik, S; Milsted, A; Miura, S; Nishiyama, K; Rungger-Brandle, E; Sears, JE; Senanayake, Pd; Shadrach, K | 1 |
| Alenina, N; Bader, M; da Costa Gonçalves, AC; Fraga-Silva, RA; Leite, R; Pinheiro, SV; Reis, AB; Reis, FM; Santos, RA; Touyz, RM; Webb, RC | 1 |
| Chappell, MC; Gallagher, PE; Groban, L; Pendergrass, KD; Pirro, NT; Yamaleyeva, LM | 1 |
| Brosnihan, KB; Ferrario, CM; Gironacci, MM; Gorzalczany, S; Pascual, M; Peña, C; Taira, C; Verrilli, MA | 1 |
| Benter, IF; Kehinde, EO; Yousif, MH | 1 |
| Campagnole-Santos, MJ; Carvalho, MB; da Mata Machado, LT; de Paula, RD; Duarte, FV; Faria-Silva, R; Fauler, B; Santos, RA | 1 |
| Brosnihan, KB; Ferrario, CM; Gallagher, PE; Joyner, J; Merrill, DC; Neves, LA; Stovall, K; Valdés, G | 1 |
| Henrique de Castro, C; Sampaio, WO; Santos, RA; Schiffrin, EL; Touyz, RM | 1 |
| Azcutia, V; Gembardt, F; Heringer-Walther, S; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF; Schultheiss, HP; Vallejo, S; Walther, T | 1 |
| Anton, L; Brosnihan, KB; Merrill, DC; Neves, LA | 1 |
| Cui, LQ; Guo, YJ; Li, WH; Wu, R; Xie, Q | 1 |
| Corvol, P; Hamming, I; Michaud, AA; Navis, G; Rushworth, CA; Turner, AJ; van Goor, H | 1 |
| Burrell, LM; Hanchapola, I; Lew, RA; Manohar, J; Ramchand, J; Smith, AI; Warner, FJ; Yarski, MA | 1 |
| Kautiainen, H; Oksala, O; Vaajanen, A; Vapaatalo, H | 1 |
| Alzamora, AC; Campagnole-Santos, MJ; Ferreira, PM; Santos, RA | 1 |
| Anton, L; Brosnihan, KB; Diz, DI; Ferrario, CM; Gallagher, PE; Gruver, C; Merrill, DC; Moorefield, C; Neves, LA; Stovall, K | 1 |
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| Lin, CS; Pan, CH; Wen, CH | 1 |
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| Arnold, AC; Diz, DI; Ferrario, CM; Ganten, D; Sakima, A | 1 |
| Chappell, MC; Ferrario, CM; Garabelli, PJ; Modrall, JG; Penninger, JM | 1 |
| Chappell, MC; Ferrario, CM; Jessup, JA; Trask, AJ | 1 |
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| Dominici, FP; Giani, JF; Gironacci, MM; Muñoz, MC; Turyn, D | 1 |
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| Averill, DB; Diz, DI; Ferrario, CM; Gallagher, PE; Ganten, D; Garcia-Espinosa, MA | 1 |
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| Cassali, GD; dos Reis, AM; Honorato-Sampaio, K; Pereira, VM; Reis, FM; Santos, RA; Santos, SH | 1 |
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| Basu, R; Guo, D; Kassiri, Z; Liu, PP; Oudit, GY; Penninger, JM; Scholey, JW; Wang, X; Zhong, J | 1 |
| Ahmad, S; Brosnihan, KB; Chappell, MC; Ferrario, CM; Gallagher, PE; Groban, L; Tallant, EA; Varagic, J | 1 |
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| Burns, WC; Burrell, LM; Dean, R; Thomas, MC; Velkoska, E | 1 |
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| Anton, L; Brosnihan, KB; Gruver, C; Merrill, DC; Moorefield, C; Neves, LA | 1 |
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| Hanasaki-Yamamoto, H; Hongyo, K; Kamide, K; Kawai, T; Oguro, R; Ohishi, M; Rakugi, H; Sugimoto, K; Takami, Y; Takeda, M; Takemura, Y; Takeshita, H; Takeya, Y; Tatara, Y; Yamamoto, K | 1 |
| Castro-Moreno, P; Del Valle-Mondragón, L; Hernández-Muñoz, R; Ibarra-Barajas, M; López-Guerrero, JJ; Pardo, JP; Pastelín-Hernández, G; Villalobos-Molina, R | 1 |
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| Adams, GN; Bilodeau, ML; Chen, A; Fang, C; Grobe, N; LaRusch, G; Mahdi, F; Morris, M; Nieman, MT; Schmaier, AA; Schmaier, AH; Stavrou, E; Warnock, M; Zhou, Y | 1 |
| Bernstein, KE; Elased, KM; Grobe, N; Leiva, O; Morris, M; Ong, FS; Schmaier, AH; Weir, NM | 1 |
| Andrade, JM; Caldeira, AP; Campagnole-Santos, MJ; de Carvalho Botelho, AC; de Paula, AM; de Pinho, L; Feltenberger, JD; Filho, AB; Guimarães, AL; Paraíso, A; Sousa Santos, SH | 1 |
| Li, P; Miao, J; Wang, Y; Zhang, W; Zhang, Y | 1 |
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| Alenina, N; Alves, F; Alzamora, A; Bader, M; Barbosa, C; Braga, J; Campagnole-Santos, MJ; Costa-Fraga, F; Ferreira, A; Fraga-Silva, RA; Jankowski, J; Jankowski, V; Kemplin, F; Kjeldsen, F; Klempin, F; Lautner, RQ; Maia, G; Martins, A; Motta-Santos, D; Oliveira, A; Passos-Silva, D; Paula, R; Peluso, AB; Pimenta, A; Raizada, M; Santos, RA; Savergnini, S; Silva, N; Sinisterra, R; Soares, E; Sousa, F; Verano-Braga, T; Villela, DC | 1 |
| Ahmad, S; Batlle, D; Brosnihan, KB; Ferrario, CM; Moniwa, N; Varagic, J; VonCannon, JL; Wysocki, J | 1 |
| Azcutia, V; Gembardt, F; Hermenegildo, C; Novella, S; Palacios, E; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF; Vallejo, S; Walther, T | 1 |
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| Chen, Q; Huang, Y; Liu, L; Pan, C; Qiu, H; Yang, Y | 1 |
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| Byku, M; Macarthur, H; Murray, J; Westfall, TC; Yang, CL | 1 |
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| Campbell, WB; Kopf, PG | 1 |
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| Li, XD; Liu, Y; Qin, S; Shen, HM; Tang, HJ; Yan, X; Zhou, YJ | 1 |
| Del Valle-Mondragón, L; Echeverría-Rodríguez, O; Hong, E | 1 |
| Clasen, T; Fähling, M; Ishak, B; Kojda, G; Mende, S; Patzak, A; Potthoff, SA; Rump, LC; Sivritas, SH; Stamer, S; Stegbauer, J; Suvorava, T; Thieme, M | 1 |
| Ji, L; Liu, W; Shi, J; Tian, M; Tong, Q; Xie, W; Zhu, D | 1 |
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| Elgazzar, EM; Hasan, HF; Mostafa, DM | 1 |
| Antlanger, M; Berlakovich, G; Böhmig, GA; Domenig, O; Eskandary, F; Fajkovic, H; Grobe, N; Gruber, C; Hellinger, R; Kain, R; Kaltenecker, CC; Kopecky, C; Kovarik, JJ; Poglitsch, M; Rahman, M; Säemann, MD; Stegbauer, J | 1 |
| Araújo, FA; Assis, AD; Mascarenhas, FNADP; Santos, RAS; Zanon, RG | 1 |
| Bi, C; Hu, B; Huang, X; Li, M; Qu, H; Song, J; Wang, L; Zhang, M | 1 |
| Acconcia, F | 1 |
| Borges, CL; Castro, CH; Colugnati, DB; de Ávila, RI; Gava, E; Kitten, GT; Lima, EM; Macedo, LM; Pedrino, GR; Valadares, MC | 1 |
| Liao, W; Wu, J | 1 |
| Beer, JH; Saeedi Saravi, SS | 1 |
| Delpino, MV; Quarleri, J | 1 |
| Dang, R; Feng, Q; Geng, C; Guo, Y; Han, W; Jiang, P; Wang, C; Wei, Z; Zhang, H | 1 |
| Bazan, SGZ; Casarini, DE; Cicogna, AC; da Silva, VL; de Campos, DHS; de Oliveira, EM; de Souza, SLB; Fernandes, T; Gatto, M; Gomes, ERM; Mota, GAF; Padovani, CR; Sant'Ana, PG; Sugizaki, MM; Vileigas, DF | 1 |
| Lu, K; Shi, C; Xia, H; Zhang, B; Zhang, P | 1 |
| Gan, R; Georgius, P; Henshaw, DJE; Noble, EP; Rosoman, NP; Sommerfeld, N | 1 |
| Correa, AMB; de Almeida, JFQ; Ferreira, AJ; Fontes, MAP; Kushmerick, C; Moreira, FA; Patel, KP; Sharma, NM; Silva, CC | 1 |
| Casalechi, M; Cassali, GD; Pereira, VM; Reis, AM; Reis, FM; Santos, RAS; Santos, SHS | 1 |
| Bhering Martins, L; Braga Tibaes, JR; Ferreira, AVM; Gomez, RS; Rodrigues, AMDS; Silva de Miranda, A; Teixeira, AL | 1 |
| Alzamora, AC; Barbosa, CM; Barbosa, MA; Campagnole-Santos, MJ; de Sousa, GG; Lima, TC; Souza Dos Santos, RA | 1 |
| Gaikwad, AB; Sharma, N | 1 |
| Gao, X; Ge, X; Jin, F; Li, S; Li, Y; Mao, N; Wei, Z; Xu, H; Yang, F; Yang, Y; Zhang, M; Zhang, Y | 1 |
| Costa-Ferreira, W; Crestani, CC; Marchi-Coelho, C; Moreno-Santos, B | 1 |
| Heng, CKM; Liao, W; Mei, D; Tan, WSD; Wong, WSF | 1 |
| Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL | 1 |
| Lv, B; Meng, L; Shen, M; Wang, M; Zhang, B | 1 |
| Li, WX; Li, Y; Lin, FH; Lin, WP; Poon, CC; Sha, NN; Shi, W; Wang, YF; Wang, YJ; Zhang, JL; Zhang, Y | 1 |
| Rakugi, H; Takeshita, H; Yamamoto, K | 1 |
| Cohen, JB; Edmonston, DL; South, AM; Sparks, MA | 1 |
| Chen, A; Desai, AA; Han, Y; Pan, Y; Tang, H; Wang, X; Xu, Y; Zhang, F | 1 |
| Chappell, MC; Gwathmey, TM; Pirro, NT; South, AM | 1 |
| Polak, Y; Speth, RC | 1 |
| Ahmed, A; Hasan, M; Rahman, MM | 1 |
| Amin, S; Bakouny, Z; Bhasin, M; Bhatt, RS; Catalano, P; Chen, CH; Choueiri, TK; Joslin, PN; Khanna, P; McKay, R; Moore, A; Naughton, M; O'Callaghan, C; Saxena, R; Signoretti, S; Soh, HJ; Walther, T | 1 |
| Bernasconi, L; Conen, A; Domenig, O; Gregoriano, C; Haubitz, S; Koch, D; Kutz, A; Mueller, B; Schuetz, P | 1 |
| Caroccia, B; Domenig, O; Iacobone, M; Lenzini, L; Piazza, M; Poglitsch, M; Prisco, S; Rossi, GP; Seccia, TM; Torresan, F; Vanderriele, PE | 1 |
| Bernstein, EA; Bernstein, KE; Cao, D; Giani, JF; Gonzalez-Villalobos, RA; Khan, Z; Okwan-Duodu, D; Shen, JZY; Veiras, LC | 1 |
| Hoang, T; Revoori, R; Rianto, F; Sparks, MA | 1 |
| Cantero-Navarro, E; Fernández-Fernández, B; Ortiz, A; Ramos, AM; Rayego-Mateos, S; Rodrigues-Diez, RR; Ruiz-Ortega, M; Sánchez-Niño, MD; Sanz, AB | 1 |
| Addai, D; Alexandrova, R; Ananiev, J; Rashev, P; Todev, A; Tolekova, A; Uzunova, VV; Zarkos, J | 1 |
| Arfsten, H; Bartko, PE; Domenig, O; Goliasch, G; Hengstenberg, C; Hülsmann, M; Mascherbauer, J; Pavo, N; Poglitsch, M; Prausmüller, S; Spinka, G; Strunk, G; Uyanik-Ünal, K; Wurm, R; Zuckermann, A | 1 |
| Brouqui, P; Devaux, CA; La Scola, B; Lagier, JC; Meddeb, L; Mege, JL; Melenotte, C; Million, M; Osman, IO; Parola, P; Raoult, D; Stein, A | 1 |
| Abreu, MAD; de Oliveira, TA; Moreira, FRC; Ramos, NE; Simões E Silva, AC | 1 |
| Galal, SM; Hasan, HF; Mohmed, HK | 1 |
| Benetti, A; Caramelli, B; Girardi, ACC; Krieger, JE; Malagrino, PA; Martins, FL; Pereira, GMD; Rentz, T; Rios, TMS; Tavares, CAM; Teixeira, SK | 1 |
| Boytsova, EB; Lopatina, OL; Morgun, AV; Salmin, VV; Salmina, AB | 1 |
| Colombo, D; Del Nonno, F; Gheblawi, M; Kassiri, Z; MacIntyre, E; Munan, M; Nikhanj, A; O'Neil, C; Oudit, GY; Poglitsch, M; Sligl, W; Wang, K | 1 |
| Javanmardi, K; Soltani Hekmat, A | 1 |
| Cao, L; Chen, Y; Fan, J; Liu, Y; Lu, L; Yin, Y | 1 |
| Bartosova, L; Galis, P; Goncalvesova, E; Klimas, J; Paulis, L; Rajtik, T | 1 |
| Kuruppu, S; Rajapakse, NW; Tran, S | 1 |
| Belfiore, A; Cammalleri, M; Chiurazzi, M; Colantuoni, A; Dal Monte, M; Damiano, S; De Conno, B; Di Maro, M; Guida, B; Lapi, D; Mondola, P; Nasti, G; Santillo, M; Serao, N; Trio, R | 1 |
| Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G | 1 |
| Alfie, J; Corradi, GR; Falcoff, NL; Gironacci, MM; Guman, GR; Iglesias, LI; Nuñez, M; Seguel, RF; Silva, MG; Tabaj, GC | 1 |
| De la Cuesta, F; Peiró, C; Romero, A; Sánchez-Ferrer, CF; Shamoon, L | 1 |
| Gallagher, PE; Grier, RDM; Melo, AC; Rahimi, O; Tallant, EA; Westwood, B | 1 |
| Annoni, F; Caruso, E; Moro, F; Taccone, FS; Zanier, ER; Zoerle, T | 1 |
| Ceroni, A; Manica, LA; Michelini, LC; Raquel, HA | 1 |
| Cui, T; Guo, Y; Hu, W; Li, C; Liu, R; Wang, X; Yin, C | 1 |
| Abdel Hafez, SMN; Abdel-Hakeem, EA; Abdel-Hamid, HA; Kamel, BA | 1 |
| Almeida-Santos, AF; Colpo, GD; Furr Stimming, E; Guatimosim, C; Joviano-Santos, JV; Kangussu, LM; Latham, LB; Machado, TCG; Miranda, AS; Rocha, NP; Simões E Silva, AC; Soares, KB; Teixeira, AL; Valadão, PAC | 1 |
| Banerjee, A; Baptista, L; Buford, TW; Carter, CS; Hernandez, A; Li, Q; Sun, Y; Verma, A; Yang, Y | 1 |
| Gupta, S; Hanif, K; Shukla, S; Tiwari, P; Tiwari, V | 1 |
| Bustamante, J; Castellar-Lopez, J; Chang, A; Fernanda Pérez, M; Luna, P; Mendoza-Torres, E; Montoya, Y; Rosales-Rada, W | 1 |
| Abdulla, MH; AlMarabeh, S; Barry, EF; Beshara, J; Johns, EJ; O'Neill, J; Parna-Gile, E | 1 |
| Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Mackay, CDA; Meechem, M; Patel, VB; Thompson, J; Wijesuriya, TM | 1 |
| Chai, YF; Chen, XS; Cui, JR; Gao, YL; Liu, YC; Meng, XL; Shou, ST; Wang, SH; Wei, W | 1 |
| Cao, M; Hao, H; Jia, R; Lan, T; Liu, Y; Pan, W; Zhao, Z; Zhou, L | 1 |
| Kopkan, L; Kratky, V; Sykora, M; Szeiffova Bacova, B; Tribulova, N | 1 |
| Apodaca, KD; Barksdale, A; Bernard, GR; Bistran-Hall, AJ; Boyle, K; Brown, SM; Busse, LW; Chen, P; Collins, SP; de Wit, M; DeClercq, J; Douglas, IS; Duggal, A; Files, DC; Gentile, N; Gibbs, KW; Ginde, AA; Hager, DN; Harkins, M; Hudock, KM; Iovine, N; Javaheri, A; Joly, MM; Khan, A; Lanspa, M; Lavieri, R; Levitt, J; Merck, LH; Moskowitz, A; Orr, M; Pulley, J; Puskarich, M; Rice, TW; Rosenberg, Y; Safdar, B; Schildcrout, JS; Schrager, H; Self, WH; Semler, MW; Shotwell, MS; Sturek, JM; Tiffany, B; Troendle, J; Venkateshaiah, L; Vonderhaar, D; Wang, L | 1 |
| Chen, L; Han, W; Mou, Z; Zhu, X | 1 |
| Chittimalli, K; Ericsson, AC; Jahan, J; Jarajapu, YPR; McAdams, ZL; Sakamuri, A | 1 |
| Chen, G; Lu, J; Ouyang, W; Shen, G | 1 |
| Abassi, Z; Aronson, D; Cohen-Segev, R; Hamoud, S; Kabala, A; Karram, T; Kinaneh, S; Nativ, O | 1 |
| Ando, Y; Chiba, Y; Hanazaki, M; Ishizaka, S; Ito, M; Sakai, H; Suto, W; Takenoya, F; Torizuka, A; Ueda, C; Watanabe, C; Yamashita, M | 1 |
| Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Patel, VB; Wijesuriya, TM | 1 |
83 review(s) available for angiotensin ii and angiotensin ii, des-phe(8)-
| Article | Year |
|---|---|
Angiotensin-(1-7): a new hormone of the angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Biotransformation; Humans; Peptide Fragments; Renin; RNA, Messenger | 1991 |
Pathways of angiotensin formation and function in the brain.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Humans; Models, Biological; Peptide Fragments | 1990 |
[Endothelial mechanisms in vasomotor effects of ACE inhibitors].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Culture Techniques; Endothelium, Vascular; Hemodynamics; Humans; Nitric Oxide; Peptide Fragments; Receptors, Bradykinin; Vasomotor System | 1994 |
Central and peripheral actions of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Brain; Medulla Oblongata; Peptide Fragments; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 1994 |
Angiotensin receptor heterogeneity in the dorsal medulla oblongata as defined by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Genetic Heterogeneity; Medulla Oblongata; Motor Neurons; Neurons, Afferent; Peptide Fragments; Receptors, Angiotensin; Vagus Nerve | 1996 |
Counterregulatory actions of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Endothelium, Vascular; Humans; Kidney; Muscle, Smooth, Vascular; Peptide Fragments; Vasodilator Agents | 1997 |
Angiotensin-(1-7): a novel vasodilator of the coronary circulation.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Circulation; Dogs; Peptide Fragments; Vasodilator Agents | 1998 |
Differential actions of angiotensin-(1-7) in the kidney.
Topics: Angiotensin I; Angiotensin II; Humans; Kidney; Peptide Fragments; Renin-Angiotensin System | 1998 |
Effect of the angiotensin-(1-7) peptide on nitric oxide release.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Muscle, Smooth, Vascular; Nitric Oxide; Peptide Fragments; Vasoconstrictor Agents; Vasodilation | 1998 |
Antihypertensive effects of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Hypertension; Peptide Fragments; Renin-Angiotensin System | 1998 |
Angiotensin-(1-7): a bioactive fragment of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System | 1998 |
Interactions among ACE, kinins and NO.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Biological Availability; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Kinins; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Ventricular Remodeling | 1999 |
Angiotensin-(1-7): an update.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Central Nervous System; Humans; Kidney; Losartan; Models, Biological; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 2000 |
Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Humans; Kidney; Kinins; Models, Biological; Peptide Fragments; Renin-Angiotensin System | 2001 |
New insights into actions of the renin-angiotensin system in the kidney: concentrating on the Ang II receptors and the newly described Ang-(1-7) and its receptor.
Topics: Angiotensin I; Angiotensin II; Humans; Kidney; Peptide Fragments; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
Cellular targets for angiotensin II fragments: pharmacological and molecular evidence.
Topics: Angiotensin I; Angiotensin II; Animals; Cells; Cystinyl Aminopeptidase; Humans; Peptide Fragments; Receptors, Angiotensin | 2002 |
Novel angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Heart; Humans; Kidney; Peptide Fragments; Reproduction | 2004 |
The renin-angiotensin system: peptides and enzymes beyond angiotensin II.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Animals; Humans; Peptide Fragments; Renin-Angiotensin System | 2005 |
Angiotensin and diabetic retinopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Diabetic Retinopathy; Humans; Hypertension; Neovascularization, Pathologic; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Retina | 2006 |
Opposite effects of angiotensin II and angiotensin (1-7) on impulse propagation, excitability and cardiac arrhythmias. Is the overexpression of ACE2 arrhythmogenic?
Topics: Action Potentials; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arrhythmias, Cardiac; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction | 2009 |
Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Atrial Fibrillation; Endomyocardial Fibrosis; Heart Atria; Humans; Inflammation; Matrix Metalloproteinases; Models, Biological; Oxidative Stress; Peptide Fragments; ras GTPase-Activating Proteins; Signal Transduction; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Ventricular Remodeling | 2008 |
Liver disease and the renin-angiotensin system: recent discoveries and clinical implications.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Humans; Hypertension, Portal; Kallikreins; Kinins; Liver; Liver Cirrhosis; Liver Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2008 |
Renin-angiotensin system revisited.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases | 2008 |
The renin-angiotensin system and diabetes: an update.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Diabetes Mellitus; Endothelium, Vascular; Humans; Hyaluronan Receptors; Insulin; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Signal Transduction | 2008 |
Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Chronic Disease; Exercise; Heart; Heart Failure; Humans; Medulla Oblongata; Neurons; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Transcription Factor AP-1; Transcription, Genetic; Up-Regulation | 2009 |
The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nephrons; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2010 |
ACE2: more of Ang-(1-7) or less Ang II?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2011 |
Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Cardiovascular Diseases; Humans; Neurons; Nitric Oxide; Oxidation-Reduction; Peptide Fragments; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2011 |
Angiotensin peptides and central autonomic regulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Humans; Hypertension; MAP Kinase Signaling System; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol 3-Kinases | 2011 |
Role of ACE2 in diastolic and systolic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Heart Failure; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction | 2012 |
Role of angiotensin in ovarian follicular development and ovulation in mammals: a review of recent advances.
Topics: Angiotensin I; Angiotensin II; Animals; Autocrine Communication; Cattle; Female; Models, Biological; Ovarian Follicle; Ovulation; Paracrine Communication; Peptide Fragments; Rabbits; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 2012 |
[Research progress in relations between renin angiotensin system and diabetic cardiomyopathy].
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Diabetic Cardiomyopathies; Humans; NF-kappa B; Oligopeptides; Peptide Fragments; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2011 |
Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Humans; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
Angiotensin peptides and nitric oxide in cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cardiovascular Diseases; Heart Failure; Humans; Nitric Oxide; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2013 |
Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent review.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Agents; Drug Design; Enzyme Activation; Enzyme Activators; Humans; Legislation, Drug; Molecular Structure; Patents as Topic; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Structure-Activity Relationship | 2012 |
The renin-angiotensin system, bone marrow and progenitor cells.
Topics: Adipogenesis; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone Marrow; Erythropoiesis; Hematopoiesis; Humans; Kidney; Mesenchymal Stem Cells; Metabolic Syndrome; Myocytes, Cardiac; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stem Cells; Tetrazoles; Valine; Valsartan | 2012 |
Angiotensin (1-7) and other angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Glucose; Humans; Kidney Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2013 |
The renin angiotensin aldosterone system and insulin resistance in humans.
Topics: Adipose Tissue; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Glucose; Hemodynamics; Humans; Insulin Resistance; Models, Animal; Muscle, Skeletal; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2013 |
Pathophysiological role of the renin-angiotensin system on erectile dysfunction.
Topics: Angiotensin I; Angiotensin II; Erectile Dysfunction; Humans; Male; Penile Erection; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2013 |
Interactions of neuropeptide y, catecholamines, and angiotensin at the vascular neuroeffector junction.
Topics: Angiotensin I; Angiotensin II; Animals; Catecholamines; Humans; Hypertension; Neuroeffector Junction; Neuropeptide Y; Peptide Fragments; Sympathetic Nervous System | 2013 |
Modulation of the action of insulin by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction | 2014 |
ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Heart Diseases; Humans; Hypertension; Kidney Diseases; Peptide Fragments; Peptidyl-Dipeptidase A | 2014 |
New components of the renin-angiotensin system: alamandine and the MAS-related G protein-coupled receptor D.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Oligopeptides; Peptide Fragments; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Risk Assessment; Sensitivity and Specificity | 2014 |
Protective axis of the renin-angiotensin system in the brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Blood Pressure; Brain; Neurotransmitter Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction | 2014 |
ACE and ACE2 in inflammation: a tale of two enzymes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
Counter-regulatory effects played by the ACE - Ang II - AT1 and ACE2 - Ang-(1-7) - Mas axes on the reactive oxygen species-mediated control of vascular function: perspectives to pharmacological approaches in controlling vascular complications.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Humans; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Vascular Diseases | 2014 |
The role of renin-angiotensin system modulation on treatment and prevention of liver diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Humans; Liver Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Rats; Renin-Angiotensin System | 2015 |
Therapeutic uses for Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Clinical Trials as Topic; Drug Design; Humans; Neoplasms; Patents as Topic; Peptide Fragments; Renin-Angiotensin System | 2016 |
Role of renin-angiotensin system in liver diseases: an outline on the potential therapeutic points of intervention.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Enzyme Activation; Enzyme Activators; Humans; Liver; Liver Diseases; Molecular Targeted Therapy; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Treatment Outcome | 2016 |
Measurement of Angiotensin Peptides: HPLC-RIA.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Humans; Peptide Fragments; Radioimmunoassay; Renin-Angiotensin System | 2017 |
Renin-Angiotensin System in Diabetes.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus; Humans; Peptide Fragments; Renin-Angiotensin System | 2017 |
Physical Exercise and ACE2-Angiotensin-(1-7)-Mas Receptor Axis of the Renin Angiotensin System.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Exercise; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2017 |
Angiotensin-converting enzyme 2-Angiotensin 1-7/1-9 system: novel promising targets for heart failure treatment.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Agents; Heart Failure; Humans; Molecular Mimicry; Molecular Targeted Therapy; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Treatment Outcome | 2018 |
Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Peptide Fragments; Protective Factors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2018 |
Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies.
Topics: Angiotensin I; Angiotensin II; Animals; Cognition Disorders; Databases, Bibliographic; Dementia; Disease Models, Animal; Humans; Memory, Short-Term; Peptide Fragments | 2018 |
The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Delivery Systems; Homeostasis; Humans; Insulin Resistance; Islets of Langerhans; Peptide Fragments; Renin-Angiotensin System | 2019 |
ACE2 in Brain Physiology and Pathophysiology: Evidence from Transgenic Animal Models.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Brain; Brain Diseases; Cardiomegaly; Models, Animal; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Serotonin; Stress, Psychological; Tryptophan | 2019 |
The Protective Arm of Renin Angiotensin System; Recent Research Progress and Expectation for New Therapeutic Approach.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Classic and Nonclassic Renin-Angiotensin Systems in the Critically Ill.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Blood Pressure; Critical Illness; Female; Homeostasis; Humans; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Respiratory Distress Syndrome; Shock, Septic; Vasoconstrictor Agents | 2019 |
Levels of angiotensin peptides in healthy and cardiovascular/renal-diseased paediatric population-an investigative review.
Topics: Adolescent; Age Factors; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Infant, Newborn; Kidney Failure, Chronic; Male; Peptide Fragments; Renin-Angiotensin System | 2019 |
Muscle wasting: A review of exercise, classical and non-classical RAS axes.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Exercise; Fibrosis; Humans; Mitochondria; Muscle, Skeletal; Muscular Atrophy; NADPH Oxidases; Peptide Fragments; Protein Biosynthesis; Reactive Oxygen Species; Renin-Angiotensin System; Ubiquitin-Protein Ligases | 2019 |
Angiotensin II and angiotensin 1-7: which is their role in atrial fibrillation?
Topics: Angiotensin I; Angiotensin II; Atrial Fibrillation; Atrial Remodeling; Humans; Peptide Fragments | 2020 |
Effect of renin-angiotensin system on senescence.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cellular Senescence; Humans; Longevity; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Signal Transduction | 2020 |
Potential influence of COVID-19/ACE2 on the female reproductive system.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Gene Expression Regulation; Genitalia, Female; Host-Pathogen Interactions; Humans; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pregnancy; Protein Binding; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2020 |
The Network of Angiotensin Receptors in Breast Cancer.
Topics: Angiotensin I; Angiotensin II; Breast Neoplasms; Female; Humans; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2020 |
The ACE2/Ang (1-7)/MasR axis as an emerging target for antihypertensive peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Vasodilation | 2021 |
ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Humans; Muscle, Skeletal; Peptide Fragments; SARS-CoV-2 | 2020 |
Coronavirus Disease 2019 and Hypertension: The Role of Angiotensin-Converting Enzyme 2 and the Renin-Angiotensin System.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Comorbidity; COVID-19; Humans; Hypertension; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Peptide Fragments; Protective Factors; Receptors, Coronavirus; Renin-Angiotensin System; Risk Factors; SARS-CoV-2; Up-Regulation | 2020 |
Research Progress on Pulmonary Arterial Hypertension and the Role of the Angiotensin Converting Enzyme 2-Angiotensin-(1-7)-Mas Axis in Pulmonary Arterial Hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Arterial Hypertension; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2022 |
Potential detrimental role of soluble ACE2 in severe COVID-19 comorbid patients.
Topics: ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Comorbidity; COVID-19; Humans; Peptide Fragments; SARS-CoV-2 | 2021 |
Novel roles of the renal angiotensin-converting enzyme.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Kidney Tubules, Proximal; Mice; Mice, Knockout; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Renin-angiotensin system and inflammation update.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoimmunity; Blood Pressure; Gene Expression Regulation; Humans; Inflammation; Kidney; Klotho Proteins; Peptide Fragments; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; T-Lymphocytes; Water-Electrolyte Balance | 2021 |
The role of renin angiotensin system in the pathophysiology of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Osteoarthritis; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Treatment Outcome | 2021 |
Molecular Mechanisms of Proteins - Targets for SARS-CoV-2 (Review).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Astrocytes; Basigin; Brain; COVID-19; Humans; Peptide Fragments; SARS-CoV-2; Serine Endopeptidases | 2021 |
Alamandine: Potential Protective Effects in SARS-CoV-2 Patients.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Oligopeptides; Peptide Fragments; Renin-Angiotensin System | 2021 |
Alternative RAS in Various Hypoxic Conditions: From Myocardial Infarction to COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Humans; Hypoxia; Lung; Myocardial Infarction; Peptide Fragments; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Cytokines; Dementia, Vascular; Humans; Hypertension; Inflammation; Peptide Fragments; Renin-Angiotensin System | 2022 |
Angiotensin-(1-7) reduces doxorubicin-induced aortic arch dysfunction in male and female juvenile Sprague Dawley rats through pleiotropic mechanisms.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Doxorubicin; Female; Humans; Male; Peptide Fragments; Pulse Wave Analysis; Rats; Rats, Sprague-Dawley | 2022 |
Angiotensin-(1-7) as a Potential Therapeutic Strategy for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage.
Topics: Angiotensin I; Angiotensin II; Brain Ischemia; Humans; Peptide Fragments; Subarachnoid Hemorrhage | 2022 |
Potential of Angiotensin-(1-7) in COVID-19 Treatment.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; COVID-19; COVID-19 Drug Treatment; COVID-19 Serotherapy; Humans; Pandemics; Peptidyl-Dipeptidase A; Renin-Angiotensin System; SARS-CoV-2 | 2023 |
Physiological and pathological roles of Ang II and Ang- (1-7) in the female reproductive system.
Topics: Angiotensin II; Female; Genitalia, Female; Humans; Placenta; Pregnancy; Renin-Angiotensin System | 2022 |
10 trial(s) available for angiotensin ii and angiotensin ii, des-phe(8)-
| Article | Year |
|---|---|
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Time Factors | 1996 |
Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Cardiac Output, Low; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Humans; Male; Peptide Fragments | 1999 |
Angiotensin(1-7) potentiates bradykinin-induced vasodilatation in man.
Topics: Adult; Angiotensin I; Angiotensin II; Bradykinin; Cross-Over Studies; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Humans; Male; omega-N-Methylarginine; Peptide Fragments; Reference Values; Vasoconstrictor Agents; Vasodilation | 2001 |
Effects of truncated angiotensins in humans after double blockade of the renin system.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Chromium Radioisotopes; Edetic Acid; Humans; Male; Natriuresis; Peptide Fragments; Potassium; Renin; Renin-Angiotensin System; Sodium; Vasopressins | 2003 |
Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium-Restricted; Enalapril; Humans; Male; Peptide Fragments; Placebos; Renin-Angiotensin System; Sodium, Dietary | 2005 |
Imidapril provides a protective effect on pulmonary hypertension induced by low ambient temperature in broiler chickens.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Chickens; Cold Temperature; Hypertension, Pulmonary; Imidazolidines; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Poultry Diseases; Proliferating Cell Nuclear Antigen; Pulmonary Artery | 2014 |
Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Double-Blind Method; Female; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2013 |
Imidapril inhibits right ventricular remodeling induced by low ambient temperature in broiler chickens.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animal Husbandry; Animals; Chickens; Cold Temperature; Gene Expression Regulation; Heart Ventricles; Housing, Animal; Imidazolidines; Peptide Fragments; Peptidyl-Dipeptidase A; Ventricular Remodeling | 2013 |
Angiotensin-(1-7)-induced renal vasodilation in hypertensive humans is attenuated by low sodium intake and angiotensin II co-infusion.
Topics: Angiotensin I; Angiotensin II; Diet, Sodium-Restricted; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Vasodilation | 2013 |
Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements.
Topics: Adult; Allostasis; Angiotensin I; Angiotensin II; Biomarkers; C-Reactive Protein; Electroencephalography; Epinephrine; Heart Rate; Humans; Interleukin-1; Interleukin-10; Interleukin-6; Male; Middle Aged; Military Personnel; Monitoring, Physiologic; Norepinephrine; North Carolina; Peptide Fragments; Pilot Projects; Self Report; Stress Disorders, Post-Traumatic; Vasopressins; Veterans | 2017 |
613 other study(ies) available for angiotensin ii and angiotensin ii, des-phe(8)-
| Article | Year |
|---|---|
Production of angiotensin-(1-7) by human vascular endothelium.
Topics: Angiotensin I; Angiotensin II; Animals; Enalaprilat; Endothelium, Vascular; Humans; Iodine Radioisotopes; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Umbilical Veins | 1992 |
In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalaprilat; Endopeptidases; Hypertension; Male; Neprilysin; Osmolar Concentration; Peptide Fragments; Prolyl Oligopeptidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serine Endopeptidases; Time Factors | 1992 |
Angiotensin-(1-7) is a potent antidiuretic peptide in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Diuresis; Dose-Response Relationship, Drug; Male; Peptide Fragments; Rats; Rats, Wistar; Water-Electrolyte Balance | 1992 |
Differential actions of angiotensin II and angiotensin-(1-7) on transmitter release.
Topics: Angiotensin I; Angiotensin II; Animals; Brain Chemistry; Male; Medulla Oblongata; Neurotransmitter Agents; Peptide Fragments; Potassium; Rats; Rats, Inbred Strains | 1992 |
Angiotensin II--derived peptides devoid of phenylalanine in position 8 have full psychotropic activity of the parent hormone.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Avoidance Learning; Behavior, Animal; Injections, Intraventricular; Male; Motor Activity; Peptide Fragments; Phenylalanine; Psychotropic Drugs; Rats; Rats, Wistar; Stereotyped Behavior; Time Factors | 1992 |
Angiotensin II is retained in gonadotrophs of pituitary cell aggregates cultured in serum-free medium but does not mimic the effects of exogenous angiotensins and luteinizing-hormone-releasing hormone on growth hormone release.
Topics: Angiotensin II; Angiotensins; Animals; Biphenyl Compounds; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Serum-Free; Female; Gonadotropin-Releasing Hormone; Growth Hormone; Imidazoles; Immunohistochemistry; Losartan; Pituitary Gland, Anterior; Radioimmunoassay; Rats; Rats, Wistar; Saralasin; Tetrazoles | 1992 |
Increased angiotensin-(1-7) in hypophysial-portal plasma of conscious sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Chromatography, High Pressure Liquid; Endopeptidases; Gonadotropin-Releasing Hormone; Median Eminence; Peptide Fragments; Peptides; Pituitary Gland; Portal System; Prolyl Oligopeptidases; Radioimmunoassay; Renin; Serine Endopeptidases; Sheep | 1992 |
Electrophysiological responses of angiotensin peptides on the rat isolated nodose ganglion.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Electrophysiology; In Vitro Techniques; Male; Nodose Ganglion; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Serotonin | 1992 |
Differential baroreceptor reflex modulation by centrally infused angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex | 1992 |
Evidence that prolyl endopeptidase participates in the processing of brain angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Dogs; Endopeptidases; Hypothalamus; In Vitro Techniques; Iodine Radioisotopes; Male; Peptide Fragments; Prolyl Oligopeptidases; Radioimmunoassay; Renin-Angiotensin System; Serine Endopeptidases | 1991 |
Angiotensin-(1-7). A member of circulating angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Dogs; Enalaprilat; Heart Rate; Male; Nephrectomy; Peptide Fragments; Peptides; Radioimmunoassay; Renin | 1991 |
Human astrocytes contain two distinct angiotensin receptor subtypes.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Astrocytes; Astrocytoma; Calcium; Cell Line; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Peptide Fragments; Prostaglandins F; Receptors, Angiotensin; Signal Transduction; Tumor Cells, Cultured | 1991 |
Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glioma; Imidazoles; Losartan; Oligopeptides; Peptide Fragments; Prostaglandins; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1991 |
Neurophysiological responses to angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Brain; Electrophysiology; Female; Iontophoresis; Neurons; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred WKY; Vasopressins | 1991 |
Biological activity of angiotensin-(1-7) heptapeptide in the hamster heart.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiac Output; Cardiomyopathies; Coronary Circulation; Cricetinae; Heart; Male; Mesocricetus; Peptide Fragments; Perfusion; Pressure; Reference Values | 1990 |
Actions of angiotensin peptides after partial denervation of the solitary tract nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Binding Sites; Denervation; Male; Medulla Oblongata; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Sinus of Valsalva | 1990 |
Angiotensin II and angiotensin (1-7) excite neurons in the canine medulla in vitro.
Topics: Action Potentials; Angiotensin I; Angiotensin II; Animals; Dogs; In Vitro Techniques; Male; Medulla Oblongata; Peptide Fragments; Vagus Nerve | 1990 |
Prostaglandin production in response to angiotensin-(1-7) in rabbit isolated vasa deferentia.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Male; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Prostaglandins E; Rabbits; Stimulation, Chemical; Vas Deferens | 1990 |
Cardiovascular effects of angiotensin-(1-7) injected into the dorsal medulla of rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Peptide Fragments; Rats; Rats, Inbred Strains | 1989 |
Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensins; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Hypothalamus; Immune Sera; Male; Peptide Fragments; Protein Processing, Post-Translational; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; In Vitro Techniques; Peptide Fragments; Rats; Receptors, Angiotensin; Saralasin | 1988 |
Biological activities of angiotensin II-(1-6)-hexapeptide and angiotensin II-(1-7)-heptapeptide in man.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Bartter Syndrome; Blood Pressure; Humans; Hyperaldosteronism; Infusions, Parenteral; Kinetics; Male; Peptide Fragments; Reference Values; Time Factors | 1986 |
Pressor and reflex sensitivity is altered in spontaneously hypertensive rats treated with angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Peptide Fragments; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Time Factors; Vasoconstrictor Agents | 1995 |
Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Indomethacin; Male; Peptide Fragments; Prostaglandins; Rats; Rats, Wistar; Renin-Angiotensin System; Vasoconstrictor Agents | 1995 |
Angiotensin-(1-7) and nitric oxide interaction in renovascular hypertension.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine; Biphenyl Compounds; Dogs; Hemodynamics; Hypertension, Renovascular; Imidazoles; Lisinopril; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Peptidyl-Dipeptidase A; Tetrazoles | 1995 |
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1995 |
Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Arginine; Coronary Vessels; Data Interpretation, Statistical; Dogs; In Vitro Techniques; Kinins; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Peptide Fragments; Receptors, Angiotensin; Stimulation, Chemical | 1995 |
Antihypertensive actions of angiotensin-(1-7) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Heart Rate; Hypertension; Infusions, Intravenous; Male; Natriuresis; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Time Factors; Vasopressins | 1995 |
Angiotensin-(1-7) binding at angiotensin II receptors in the rat brain.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain; Cell Nucleus; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1995 |
Angiotensin-(1-7) and nitric oxide synthase in the hypothalamo-neurohypophysial system.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Animals; Cerebral Ventricles; Hypothalamo-Hypophyseal System; Immunohistochemistry; Male; NADP; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus | 1993 |
Differential responses to angiotensin-(1-7) in the feline mesenteric and hindquarters vascular beds.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arginine; Biphenyl Compounds; Cats; Hindlimb; Imidazoles; Losartan; Meclofenamic Acid; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Perfusion; Tetrazoles; Vascular Resistance; Vasoconstriction | 1993 |
On the plasticity of the cerebellar renin-angiotensin system: localization of components and effects of mechanical perturbation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cerebellum; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Hybridization; Male; Microscopy, Confocal; Neuroglia; Neuronal Plasticity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 1994 |
Angiotensin(1-7) is an antagonist at the type 1 angiotensin II receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Rabbits; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Association between the natriuretic action of angiotensin-(1-7) and selective stimulation of renal prostaglandin I2 release.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Body Water; Electrolytes; Epoprostenol; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Natriuresis; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance | 1995 |
Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Brain; Female; Hypertension; Immune Sera; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1995 |
Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule.
Topics: Adsorption; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Peptide Fragments; Perfusion; Permeability; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
[7-D-ALA]-angiotensin-(1-7): selective antagonism of angiotensin-(1-7) in the rat paraventricular nucleus.
Topics: Action Potentials; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Male; Neurons; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1994 |
Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors.
Topics: Adrenal Glands; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Female; Heart Rate; In Vitro Techniques; Injections, Intraventricular; Male; Medulla Oblongata; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Uterine Contraction | 1994 |
Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles | 1994 |
Plasma angiotensin(1-7) immunoreactivity is increased by salt load, water deprivation, and hemorrhage.
Topics: Angiotensin I; Angiotensin II; Animals; Hemorrhage; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Sodium Chloride; Water Deprivation; Water-Electrolyte Imbalance | 1994 |
Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Cerebral Cortex; Female; Hypertension; Hypothalamus; Medulla Oblongata; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin | 1994 |
Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Peptide Fragments; Pulmonary Circulation; Pyridines; Tetrazoles; Vascular Resistance | 1994 |
Natriuretic action of angiotensin(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Diuresis; Glomerular Filtration Rate; Kidney; Kidney Tubules; Male; Natriuresis; Peptide Fragments; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1994 |
Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Arginine; Bradykinin; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Molecular Sequence Data; Muscle Relaxation; Nitric Oxide; Nitroarginine; Peptide Fragments; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Vasodilator Agents | 1994 |
Effects of angiotensin II and angiotensin-(1-7) on the release of [3H]norepinephrine from rat atria.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Interactions; Electric Stimulation; Female; Heart; Heart Atria; Imidazoles; Losartan; Myocardium; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles | 1994 |
Cardiovascular effects produced by micro-injection of angiotensin-(1-7) on vasopressor and vasodepressor sites of the ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Organ Specificity; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 1993 |
Comparative effects of angiotensin-(1-7) and angiotensin II on piglet pial arterioles.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Arterioles; Cerebral Arteries; Female; Indomethacin; Male; Peptide Fragments; Pia Mater; Prostaglandins; Swine; Vasodilator Agents | 1993 |
Modulation of phospholipase A2 activity and sodium transport by angiotensin-(1-7).
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin I; Angiotensin II; Animals; Biological Transport; Cells, Cultured; Kidney Tubules, Proximal; Lysophosphatidylcholines; Male; Peptide Fragments; Phospholipases A; Phospholipases A2; Rabbits; Sodium | 1993 |
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst | 1993 |
Alterations in prostaglandin production in spontaneously hypertensive rat smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Dinoprostone; Epoprostenol; Hypertension; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1993 |
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Indoles; Male; Peptide Fragments; Perindopril; Radioimmunoassay; Rats; Rats, Inbred SHR; Renin; Tissue Distribution | 1995 |
Angiotensin II and angiotensin-(1-7) effects on free cytosolic sodium, intracellular pH, and the Na(+)-H+ antiporter in vascular smooth muscle.
Topics: Amiloride; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cytosol; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Ouabain; Peptide Fragments; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1996 |
Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Vessels; Dogs; Kinins; Male; Nitric Oxide; Peptide Fragments; Receptors, Angiotensin; Vasodilation | 1996 |
Evidence for a physiological role of angiotensin-(1-7) in the control of hydroelectrolyte balance.
Topics: Angiotensin I; Angiotensin II; Animals; Male; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System; Water-Electrolyte Balance | 1996 |
The association of thirst, sodium appetite and vasopressin release with c-fos expression in the forebrain of the rat after intracerebroventricular injection of angiotensin II, angiotensin-(1-7) or carbachol.
Topics: Angiotensin I; Angiotensin II; Animals; Appetite; Carbachol; Drinking Behavior; Injections, Intraventricular; Male; Peptide Fragments; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Sodium; Thirst; Vasopressins | 1995 |
Angiotensin-(1-7) inhibits vascular smooth muscle cell growth.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Cattle; Cell Count; Cell Division; Cells, Cultured; Data Interpretation, Statistical; Male; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Receptors, Angiotensin; Thymidine | 1996 |
Renal actions of angiotensin-(1-7): in vivo and in vitro studies.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Hemodynamics; Kidney; Kidney Tubules, Proximal; Male; Nystatin; Osmolar Concentration; Ouabain; Oxygen Consumption; Peptide Fragments; Rats; Rats, Wistar; Renal Circulation; Sodium-Potassium-Exchanging ATPase | 1996 |
Effect of acute volume expansion associated with salt load on the profile of plasma angiotensins in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine Vasopressin; Male; Peptide Fragments; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride; Water-Electrolyte Balance | 1996 |
Pressor action of angiotensin I at the ventrolateral medulla: effect of selective angiotensin blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Ramipril; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Epoprostenol; Humans; Hypertension; Peptide Fragments | 1996 |
Bovine aortic endothelial cells contain an angiotensin-(1-7) receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Cattle; Endothelium, Vascular; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 1997 |
Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Male; Peptide Fragments; Vasodilation | 1997 |
Hypothalamic substance P release. Attenuated angiotensin responses in mRen2(27) transgenic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Hypothalamus; Male; Peptide Fragments; Rats; Substance P; Vasoconstrictor Agents | 1997 |
Angiotensin II activates distinct signal transduction pathways in astrocytes isolated from neonatal rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Bradykinin; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Epoprostenol; Humans; Hypothalamus; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol Diacylglycerol-Lyase; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Type C Phospholipases | 1997 |
Cardiovascular effects produced by microinjection of angiotensins and angiotensin antagonists into the ventrolateral medulla of freely moving rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles; Time Factors | 1997 |
Possible participation of nitric oxide in the increase of norepinephrine release caused by angiotensin peptides in rat atria.
Topics: Angiotensin I; Angiotensin II; Animals; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Female; Heart Atria; Heart Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar; Sympathomimetics | 1997 |
Angiotensin-(1-7) induces bradykinin-mediated hypotensive responses in anesthetized rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Hypotension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1997 |
Potentiation of the hypotensive effect of bradykinin by short-term infusion of angiotensin-(1-7) in normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Drug Synergism; Hypertension; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar | 1997 |
Role of angiotensin-(1-7) in the modulation of the baroreflex in renovascular hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Enalapril; Heart Rate; Hypertension, Renovascular; Injections, Intraventricular; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Wistar; Reflex | 1997 |
Angiotensin-(1-7) and the rat aorta: modulation by the endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1997 |
Effect of intratubular application of angiotensin 1-7 on nephron function.
Topics: Absorption; Angiotensin I; Angiotensin II; Animals; Feedback; Infusions, Parenteral; Kidney Function Tests; Kidney Tubules; Loop of Henle; Male; Nephrons; Peptide Fragments; Rats; Rats, Wistar | 1997 |
Signal transduction mechanisms involved in angiotensin-(1-7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Peptide Fragments; Phospholipases A; Phospholipases A2; Prostaglandins; Rabbits; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Pressure; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Kidney; Mice; Models, Cardiovascular; Muscle, Smooth, Vascular; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 1997 |
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1998 |
Metabolism of angiotensin-(1-7) by angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cell Membrane; Dogs; Humans; Kinetics; Lisinopril; Lung; Models, Chemical; Peptide Fragments; Peptidyl-Dipeptidase A | 1998 |
Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Immunoglobulin G; Lisinopril; Losartan; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Vasodilation | 1998 |
Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects.
Topics: Adult; Age Factors; Angiotensin I; Angiotensin II; Cross-Sectional Studies; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments | 1998 |
N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Bradykinin; Chlorides; CHO Cells; Cricetinae; Enzyme Repression; Humans; Hydrolysis; Peptide Fragments; Peptidyl-Dipeptidase A; Substrate Specificity; Transfection | 1998 |
Angiotensin 1-7 induces bradykinin-mediated relaxation in porcine coronary artery.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Vessels; Imidazoles; In Vitro Techniques; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Swine; Vasodilation | 1998 |
Angiotensin-(1-7) immunoreactivity in the hypothalamus of the (mRen-2d)27 transgenic rat.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Female; Hypothalamus; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Mice; Oxytocin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tissue Distribution; Vasopressins | 1998 |
[7-D-ALA]-angiotensin 1-7 blocks renal actions of angiotensin 1-7 in the anesthetized rat.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Kidney; Kidney Function Tests; Kidney Tubules, Proximal; Losartan; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Circulation | 1998 |
Diuresis and natriuresis produced by long term administration of a selective Angiotensin-(1-7) antagonist in normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Diuresis; Male; Natriuresis; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Time Factors | 1998 |
Converting enzyme determines plasma clearance of angiotensin-(1-7).
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Blood Pressure; Chromatography, High Pressure Liquid; Drug Combinations; Half-Life; Lisinopril; Losartan; Male; Metabolic Clearance Rate; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Species Specificity | 1998 |
Effect of angiotensin-(1-7) on ATPase activities in several tissues.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Kidney; Liver; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Sheep; Sodium-Potassium-Exchanging ATPase; Synaptosomes | 1998 |
Interaction of bradykinin and angiotensin-(1-7) in the central modulation of the baroreflex control of the heart rate.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Animals; Baroreflex; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Effect of selective angiotensin antagonists on the antidiuresis produced by angiotensin-(1-7) in water-loaded rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Diuresis; Drinking; Kidney; Losartan; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Agents | 1998 |
Angiotensin-(1-7) reduces smooth muscle growth after vascular injury.
Topics: Angiotensin I; Angiotensin II; Animals; Carotid Artery Injuries; Carotid Artery, Common; Catheterization; Cell Division; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tunica Intima | 1999 |
Differential response of angiotensin peptides in the urine of hypertensive animals.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Body Weight; Drinking; Electrolytes; Hemodynamics; Hypertension; Lisinopril; Losartan; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 1999 |
Angiotensin-(1-7) can interact with the rat proximal tubule AT(4) receptor system.
Topics: Angiotensin I; Angiotensin II; Animals; Cattle; Cells, Cultured; Kidney Tubules, Proximal; Oxygen Consumption; Peptide Fragments; Rats; Receptors, Angiotensin; Sodium | 1999 |
Angiotensin-(1-7) is a modulator of the human renin-angiotensin system.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Data Interpretation, Statistical; Female; Heart Atria; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Vasoconstriction | 1999 |
Haemorrhage increases the pressor effect of angiotensin-(1-7) but not of angiotensin II at the rat rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hemorrhage; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Wistar; Sympathetic Nervous System | 1999 |
State-of-the-Art lecture. Antiproliferative actions of angiotensin-(1-7) in vascular smooth muscle.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Diseases; Cell Division; Humans; Muscle, Smooth, Vascular; Peptide Fragments | 1999 |
Cardiovascular effects of angiotensin-(1-7) in conscious spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Hypertension; Infusions, Intravenous; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1999 |
Angiotensin-(1-7) binds at the type 1 angiotensin II receptors in rat renal cortex.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Iodine Radioisotopes; Kidney Cortex; Losartan; Male; Peptide Fragments; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin | 1999 |
Synergistic effect of angiotensin-(1-7) on bradykinin arteriolar dilation in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Enalaprilat; Mesenteric Arteries; Nitric Oxide; Peptide Fragments; Prostaglandins; Rats; Rats, Wistar; Receptor, Bradykinin B2; Vasodilation; Vasodilator Agents | 1999 |
Angiotensin III depressor action in the conscious rabbit is blocked by losartan but not PD 123319.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Imidazoles; Losartan; Male; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Opposing actions of angiotensins on angiogenesis.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Division; Male; Mice; Neovascularization, Physiologic; Peptide Fragments; Wound Healing | 2000 |
Effect of intrarenal infusion of angiotensin-(1-7) in the dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Dogs; Female; Glomerular Filtration Rate; Imidazoles; Infusions, Intra-Arterial; Kidney; Losartan; Male; Peptide Fragments; Receptors, Angiotensin; Renal Artery; Renal Circulation; Tetrazoles; Urodynamics; Vasodilator Agents | 2000 |
Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man.
Topics: Angiotensin I; Angiotensin II; Arteries; Drug Interactions; Forearm; Humans; Male; Norepinephrine; Peptide Fragments; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Angiotensin-(1-7) increases osmotic water permeability in isolated toad skin.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Anura; Humans; Losartan; Oxytocin; Peptide Fragments; Permeability; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Skin; Skin Absorption; Vasoconstrictor Agents; Vasotocin; Water | 2000 |
Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Blood Pressure Determination; Diet, Sodium-Restricted; Dipeptides; Dose-Response Relationship, Drug; Hypertension; Male; Peptide Fragments; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin | 2000 |
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 2000 |
Pathways for angiotensin-(1---7) metabolism in pulmonary and renal tissues.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Hydrolysis; In Vitro Techniques; Kidney; Lung; Male; Microvilli; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats | 2000 |
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine | 2000 |
Angiotensin-(1-7) does not affect norepinephrine neuronal uptake or catabolism in rat hypothalamus and atria.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Biological Transport; Catechol O-Methyltransferase; Female; Heart Atria; Hypothalamus; Monoamine Oxidase; Myocardium; Neurons; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar | 2000 |
Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Male; Microinjections; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Angiotensin; Solitary Nucleus | 2000 |
Angiotensin-(1--7) in the ovine fetus.
Topics: Allantois; Amniotic Fluid; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Female; Fetal Blood; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Glomerular Filtration Rate; Kidney; Mice; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Sheep | 2001 |
Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arterioles; Bradykinin; Drug Synergism; Hypertension; Male; Mesenteric Arteries; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation | 2001 |
Effects of angiotensin IV and angiotensin-(1-7) on basal and angiotensin II-stimulated cytosolic Ca2+ in mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium; Cell Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glomerular Mesangium; Inositol Phosphates; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents | 2001 |
Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Imidazoles; Losartan; Male; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptide Fragments; Prostheses and Implants; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2001 |
Downregulation of the AT1A receptor by pharmacologic concentrations of Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Inositol Phosphates; Peptide Fragments; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2001 |
Angiotensin-(1-7) downregulates the angiotensin II type 1 receptor in vascular smooth muscle cells.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cells, Cultured; Down-Regulation; Imidazoles; Male; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regression Analysis; Tetrazoles; Type C Phospholipases | 2001 |
The differential effect of angiotensin II and angiotensin 1-7 on norepinephrine, epinephrine, and dopamine concentrations in rat hypothalamus: the involvement of angiotensin receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Catecholamines; Dopamine; Epinephrine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Neurons; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin | 2001 |
Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradykinin; Heart Ventricles; In Vitro Techniques; Indomethacin; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Rats; Rats, Wistar | 2001 |
Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cell Membrane; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Tubules, Proximal; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saralasin; Sodium-Potassium-Exchanging ATPase; Swine | 2002 |
Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradykinin; Dogs; Heart; Hemodynamics; Imidazoles; Microdialysis; Myocardium; Peptide Fragments; Peptides; Pyridines | 2002 |
Effect of angiotensin-(1-7) on jejunal absorption of water in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; Indomethacin; Jejunum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyridines; Rats; Rats, Wistar; Time Factors; Water | 2002 |
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cyclic GMP; Dinoprostone; Epoprostenol; Hypertension; Male; Nitric Oxide; Peptide Fragments; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Salts; Thromboxane A2; Thromboxane B2; Time Factors | 2002 |
Urinary vasodilator and vasoconstrictor angiotensins during menstrual cycle, pregnancy, and lactation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Female; Humans; Lactation; Menstrual Cycle; Peptide Fragments; Pregnancy; Vasoconstriction; Vasodilation | 2001 |
Formation of angiotensin-(1-7) from angiotensin II by the venom of Conus geographus.
Topics: Angiotensin I; Angiotensin II; Animals; CHO Cells; Cricetinae; Humans; omega-Conotoxin GVIA; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tritium | 2002 |
Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Male; Norepinephrine; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Accelerated recovery from irradiation injury by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Bone Marrow Cells; Colony-Forming Units Assay; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Leukocyte Count; Lymphocyte Count; Megakaryocytes; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Platelet Count; Radiation Injuries, Experimental; Recombinant Proteins; Stem Cells | 2002 |
Effects of angiotensins on day-night fluctuations and stress-induced changes in blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Blood Pressure; Circadian Rhythm; Drug Administration Schedule; Heart Rate; Injections, Subcutaneous; Male; Peptide Fragments; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Telemetry | 2002 |
Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Brain; Cardiovascular System; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reference Values; Solitary Nucleus | 2002 |
Renal microvascular actions of angiotensin II fragments.
Topics: Angiotensin I; Angiotensin II; Animals; Hydronephrosis; In Vitro Techniques; Male; Microcirculation; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Vasoconstrictor Agents; Vasodilation | 2002 |
L-158,809 and (D-Ala(7))-angiotensin I/II (1-7) decrease PAI-1 release from human umbilical vein endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibrinolytic Agents; Humans; Imidazoles; Peptide Fragments; Plasminogen Activator Inhibitor 1; Tetrazoles; Tissue Plasminogen Activator; Umbilical Veins | 2002 |
Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Thiazepines | 2002 |
Hypotensive effect of ANG II and ANG-(1-7) at the caudal ventrolateral medulla involves different mechanisms.
Topics: Adrenergic Antagonists; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cholinergic Antagonists; Depression, Chemical; Heart Rate; Male; Medulla Oblongata; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 2002 |
Angiotensin-(1-7) inhibits angiotensin II-induced signal transduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Enzyme Activation; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Intrarenal infusion of angiotensin-(1-7) modulates renal functional responses to exogenous angiotensin II in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Glomerular Filtration Rate; Imidazoles; In Vitro Techniques; Kidney; Kidney Function Tests; Male; Organ Size; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Circulation; Sodium; Urodynamics | 2002 |
Angiotensin-(1-7) in normal and preeclamptic pregnancy.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Hormones; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Reference Values; Renin | 2002 |
Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Male; Peptide Fragments; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance; Vasodilator Agents | 2003 |
Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cicatrix; Female; Mice; Mice, Inbred NOD; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors; Wound Healing | 2003 |
Characterization of a new selective antagonist for angiotensin-(1-7), D-pro7-angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Culture Techniques; Male; Peptide Fragments; Rats; Rats, Wistar; Renal Agents; Vasodilation | 2003 |
Effect of angiotensin II and angiotensin(1-7) on hematopoietic recovery after intravenous chemotherapy.
Topics: Angiotensin I; Angiotensin II; Animals; Antineoplastic Agents; Blood Platelets; Cyclophosphamide; Female; Fluorouracil; Hematopoiesis; Hematopoietic Stem Cells; Leukocytes; Mice; Peptide Fragments | 2003 |
Angiotensin-(1-7): a novel peptide in the ovary.
Topics: Angiotensin I; Angiotensin II; Animals; Chorionic Gonadotropin; Estrus; Female; Horses; In Vitro Techniques; Osmolar Concentration; Ovary; Peptide Fragments; Proestrus; Rats; Rats, Wistar | 2003 |
Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2003 |
Effects of angiotensin-(1-7) and other bioactive components of the renin-angiotensin system on vascular resistance and noradrenaline release in rat kidney.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Kidney; Male; Norepinephrine; Peptide Fragments; Rats; Rats, Inbred WKY; Renin-Angiotensin System; Synaptic Transmission; Vascular Resistance; Vasoconstrictor Agents | 2003 |
Effects of different angiotensins during acute, double blockade of the renin system in conscious dogs.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Consciousness; Diuresis; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Natriuresis; Peptide Fragments; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Vasopressins | 2003 |
Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Female; Immunohistochemistry; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2003 |
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptide Fragments; Prostaglandins; Rats; Rats, Sprague-Dawley | 2003 |
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype.
Topics: Adult; Angiotensin I; Angiotensin II; Antihypertensive Agents; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Vasoconstrictor Agents | 2003 |
Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate.
Topics: Adult; Angiotensin I; Angiotensin II; Coronary Vessels; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Peptide Fragments | 2003 |
Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Carboxypeptidases; Cardiac Output, Low; Female; Heart Ventricles; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Up-Regulation | 2003 |
Angiotensin-(1-7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Antidiuretic Hormone Receptor Antagonists; Biological Transport; Colforsin; Cyclic AMP; Kidney Tubules, Collecting; Osmosis; Peptide Fragments; Permeability; Protein Isoforms; Rats; Receptors, Vasopressin; Signal Transduction; Water | 2003 |
Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cerebral Ventricles; Cerebrospinal Fluid; Heart Rate; Hemorrhage; Hypertension; Hypotension; Hypothalamus; Injections, Intraventricular; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Shock, Hemorrhagic; Species Specificity | 2003 |
The role of Ang (1-7) in mediating the chronic hypotensive effects of losartan in normal rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Drug Interactions; Heart Rate; Hypotension; Losartan; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2003 |
Localization of carboxypeptidase A-like enzyme in rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxypeptidases A; Kidney; Peptide Fragments; Peptides; Rats | 2003 |
Angiotensin-(1-7) modulates vascular resistance and sympathetic neurotransmission in kidneys of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Kidney; Male; Norepinephrine; Organ Culture Techniques; Peptide Fragments; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Stimulation, Chemical; Sympathetic Nervous System; Vascular Resistance | 2004 |
The role of bradykinin, AT2 and angiotensin 1-7 receptors in the EDRF-dependent vasodilator effect of angiotensin II on the isolated mesenteric vascular bed of the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Endothelium-Dependent Relaxing Factors; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation | 2004 |
Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Bradykinin; Hypertension; Hypothalamus; Imidazoles; In Vitro Techniques; Nitric Oxide; Norepinephrine; Peptide Fragments; Potassium; Pyridines; Rats; Rats, Wistar | 2004 |
Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Carboxypeptidases; Diuresis; Gene Expression Regulation; Hypotension; Kidney; Mice; Mice, Knockout; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Polyuria; Renin-Angiotensin System; RNA, Messenger | 2004 |
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomyopathy, Hypertrophic; Coronary Vessels; Disease Models, Animal; Enzyme Induction; Imidazoles; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2004 |
Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Drug Synergism; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Wistar | 2004 |
Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cattle; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Pulmonary Artery; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.
Topics: Adjuvants, Immunologic; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Imidazoles; Kidney Cortex; Losartan; Peptide Fragments; Pertussis Toxin; Pyridines; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents | 2004 |
The renin angiotensin system in childhood hypertension: selective increase of angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Angiotensin I; Angiotensin II; Calcium Channel Blockers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hypertension; Male; Peptide Fragments; Renin; Renin-Angiotensin System | 2004 |
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Binding Sites; Carboxypeptidases; CHO Cells; Cricetinae; Cricetulus; Humans; Hydrolysis; Kinetics; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Substrate Specificity | 2004 |
Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Carboxypeptidases; Cardiac Output, Low; Case-Control Studies; Coronary Circulation; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A | 2004 |
The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Kidney Tubules, Proximal; Male; Mass Spectrometry; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 2005 |
Chronic infusion of angiotensin-(1-7) reduces heart angiotensin II levels in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; DNA Primers; Male; Myocardium; Peptide Fragments; Peptides; Polymerase Chain Reaction; Protein Structure, Tertiary; Radioimmunoassay; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2005 |
Low sodium diet inhibits the local counter-regulator effect of angiotensin-(1-7) on angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Diet, Sodium-Restricted; Endothelium, Vascular; In Vitro Techniques; Male; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction | 2004 |
Pharmacological concentration of angiotensin-(1-7) activates NADPH oxidase after ischemia-reperfusion in rat heart through AT1 receptor stimulation.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Enzyme Activation; Heart; In Vitro Techniques; Losartan; Male; Myocardial Ischemia; Myocardium; NADPH Oxidases; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Reperfusion | 2005 |
Effects of angiotensin-(1-7) blockade on renal function in rats with enhanced intrarenal Ang II activity.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Diuresis; Glomerular Filtration Rate; Kidney; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2005 |
Cardiovascular effects of angiotensin II and angiotensin-(1-7) at the RVLM of trained normotensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Wistar | 2005 |
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Atenolol; Carboxypeptidases; Carotid Arteries; Gene Expression Regulation, Enzymologic; Hydralazine; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasodilator Agents | 2005 |
Chronic administration of angiotensin-(1-7) attenuates pressure-overload left ventricular hypertrophy and fibrosis in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Blood Pressure; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardium; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2005 |
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Gene Expression Regulation; Lisinopril; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; RNA, Messenger | 2005 |
[Angiotensin-(1-7) modulates fibrinolytic imbalance induced by oxidized low-density lipoprotein in cultured human umbilical vein endothelial cells].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Cells, Cultured; Endothelium, Vascular; Humans; Lipoproteins, LDL; Peptide Fragments; Plasminogen Activator Inhibitor 1; Tissue Plasminogen Activator; Umbilical Veins | 2005 |
Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Imidazoles; Kidney; Microinjections; Muscimol; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System | 2005 |
Short-term angiotensin(1-7) receptor MAS stimulation improves endothelial function in normotensive rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reference Values; Vasodilator Agents | 2005 |
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Sulfonic Acids; Tetrazoles; Time Factors | 2005 |
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Drug Synergism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents | 2005 |
Angiotensin-(1-7) enhances anti-aggregatory effects of the nitric oxide donor sodium nitroprusside.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Angiotensin I; Angiotensin II; Antihypertensive Agents; Coronary Disease; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Nitric Oxide Donors; Nitroprusside; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasoconstrictor Agents | 2005 |
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Astrocytes; Carboxypeptidases; Cells, Cultured; Cerebellum; Female; Gene Expression Regulation; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2006 |
Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Gene Expression Regulation, Enzymologic; Hypertension, Renal; Kidney; Lisinopril; Losartan; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Receptors, Angiotensin; Renin-Angiotensin System | 2005 |
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Genotype; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Rats, Inbred Lew; Rats, Mutant Strains | 2006 |
Baroreflex modulation by angiotensins at the rat rostral and caudal ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Models, Biological; Nitric Oxide Synthase Type I; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System; Sympathetic Nervous System | 2006 |
Are multiple angiotensin receptor types involved in angiotensin (1-7) actions on isolated rat portal vein.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Portal Vein; Rats; Receptors, Angiotensin | 2005 |
Does angiotensin (1-7) contribute to the anti-proteinuric effect of ACE-inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibiotics, Antineoplastic; Blood Pressure; Body Weight; Creatine; Creatinine; Doxorubicin; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Wistar | 2005 |
Localized accumulation of angiotensin II and production of angiotensin-(1-7) in rat luteal cells and effects on steroidogenesis.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Luteal Cells; Peptide Fragments; Rats; Signal Transduction; Steroids; Subcellular Fractions; Tissue Distribution | 2006 |
New mass spectrometric assay for angiotensin-converting enzyme 2 activity.
Topics: Angiotensin I; Angiotensin II; Animals; Humans; Isoenzymes; Kidney; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; JNK Mitogen-Activated Protein Kinases; Kidney Tubules, Proximal; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 2006 |
Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blotting, Western; Female; In Vitro Techniques; Iodine Radioisotopes; Kidney Tubules, Proximal; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Sheep | 2007 |
Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Down-Regulation; Enalapril; Hemodynamics; Male; Myocardial Infarction; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction; Ventricular Function, Left | 2006 |
The role of angiotensin(1-7) in renal vasculature of the rat.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; In Vitro Techniques; Kidney Glomerulus; Male; Peptide Fragments; Rats; Rats, Wistar; Renal Artery; Renal Circulation; Vasoconstrictor Agents | 2006 |
Endothelium-derived steroidogenic factor enhances angiotensin II-stimulated aldosterone release by bovine zona glomerulosa cells.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned; Endothelium; Iodine Radioisotopes; Peptide Fragments; Peptides; Vasoconstrictor Agents; Zona Glomerulosa | 2007 |
Effects of genetic deletion of angiotensin-(1-7) receptor Mas on cardiac function during ischemia/reperfusion in the isolated perfused mouse heart.
Topics: Angiotensin I; Angiotensin II; Animals; Diastole; Mice; Mice, Knockout; Myocardial Ischemia; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Reperfusion; Systole | 2006 |
Circulating renin Angiotensin system in childhood chronic renal failure: marked increase of Angiotensin-(1-7) in end-stage renal disease.
Topics: Adolescent; Angiotensin I; Angiotensin II; Angiotensins; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Disease Progression; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2006 |
Influence of gender and genetic variability on plasma angiotensin peptides.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Genotype; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Sex Factors | 2006 |
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7).
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart; Hypertension; Male; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2007 |
Evidence for a new angiotensin-(1-7) receptor subtype in the aorta of Sprague-Dawley rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation | 2007 |
The renin-angiotensin system in a rat model of hepatic fibrosis: evidence for a protective role of Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cytoprotection; Hydroxyproline; Liver; Liver Cirrhosis; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Transforming Growth Factor beta1 | 2007 |
Angiotensin-(1-7) potentiates responses to bradykinin but does not change responses to angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Carotid Artery, External; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Male; Meclofenamic Acid; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
The pregnancy-induced increase of plasma angiotensin-(1-7) is blunted in gestational diabetes.
Topics: Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Diabetes, Gestational; Female; Gestational Age; Humans; Peptide Fragments; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Radioimmunoassay; Renin-Angiotensin System | 2007 |
Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Cardiomegaly; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Kinetics; Leucine; Male; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin | 2007 |
Effects of angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Nitric Oxide; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Splanchnic Circulation; Streptozocin | 2007 |
Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Gene Expression; Imidazoles; Male; Myocardium; Nitrates; Nitrites; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Ventricular Remodeling | 2006 |
Angiotensin-(3-7) pressor effect at the rostral ventrolateral medulla.
Topics: Anesthetics, Intravenous; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Pulsatile Flow; Rats; Rats, Wistar; Urethane | 2007 |
Reduced circulating levels of angiotensin-(1--7) in systemic sclerosis: a new pathway in the dysregulation of endothelial-dependent vascular tone control.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Epoprostenol; Female; Humans; Male; Middle Aged; Neprilysin; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Scleroderma, Systemic; Vasoconstrictor Agents | 2007 |
Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype.
Topics: Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Female; Gene Deletion; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System | 2007 |
Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; CD13 Antigens; Cells, Cultured; Glutamyl Aminopeptidase; Humans; Mesangial Cells; Mice; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Podocytes; Protease Inhibitors; Renin; Renin-Angiotensin System; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Evaluation of angiotensin converting enzyme (ACE)-like activity of acellular hemoglobin.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Enzyme-Linked Immunosorbent Assay; Hemoglobins; Humans; Hydrogen Peroxide; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Spectrophotometry; Substrate Specificity; Vasoconstriction | 2007 |
Association of somatic and N-domain angiotensin-converting enzymes from Wistar rat tissue with renal dysfunction in diabetes mellitus.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Hypoglycemic Agents; Insulin; Kidney; Male; Molecular Weight; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.
Topics: Androstadienes; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Insulin; Insulin Receptor Substrate Proteins; Janus Kinase 2; Losartan; Male; Myocardium; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Tyrphostins; Wortmannin | 2007 |
On the mechanism of coronary vasodilation induced by angiotensin-(1-7) in the isolated guinea pig heart.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Bradykinin; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Vasodilation | 2007 |
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.
Topics: Acetophenones; Allopurinol; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Drug Antagonism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Onium Compounds; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxides | 2007 |
Angiotensin II and its receptor subtypes in the human retina.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Binding, Competitive; Blotting, Western; Female; Fluorescent Antibody Technique, Indirect; Humans; Male; Microscopy, Confocal; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retina; Tissue Donors | 2007 |
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium Chloride, Dietary; Vasodilator Agents | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Increased hypothalamic angiotensin-(1-7) levels in rats with aortic coarctation-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aortic Coarctation; Hypertension; Hypothalamus; Kidney; Male; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erectile Dysfunction; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penis; Peptide Fragments; Peptides; Potassium Channel Blockers; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Evidence for Mas-mediated bradykinin potentiation by the angiotensin-(1-7) nonpeptide mimic AVE 0991 in normotensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Vasodilator Agents | 2007 |
ACE2 and ANG-(1-7) in the rat uterus during early and late gestation.
Topics: Amnion; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Decidua; Disease Models, Animal; Epithelial Cells; Female; Hypertension, Pregnancy-Induced; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Uterus; Yolk Sac | 2008 |
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells.
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; CSK Tyrosine-Protein Kinase; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; NADPH Oxidases; Peptide Fragments; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; src-Family Kinases | 2007 |
Endothelial dysfunction through genetic deletion or inhibition of the G protein-coupled receptor Mas: a new target to improve endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Bradykinin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation | 2007 |
Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Losartan; Neovascularization, Physiologic; Peptide Fragments; Pyridines; Receptors, Angiotensin; Umbilical Veins; Vasoconstrictor Agents | 2007 |
ACE2 overexpression inhibits angiotensin II-induced monocyte chemoattractant protein-1 expression in macrophages.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Cell Line; Chemokine CCL2; Gene Expression Regulation; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2008 |
Differential regulation of renal angiotensin-converting enzyme (ACE) and ACE2 during ACE inhibition and dietary sodium restriction in healthy rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diet, Sodium-Restricted; Gene Expression Regulation, Enzymologic; Kidney; Lisinopril; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor.
Topics: Acetonitriles; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antiporters; Blotting, Western; Cations, Divalent; Chelating Agents; Female; Humans; Immunoprecipitation; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Plasma; Recombinant Proteins; Subcellular Fractions | 2008 |
Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Imidazoles; Injections; Intraocular Pressure; Male; Oligopeptides; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Tonometry, Ocular; Vitreous Body | 2008 |
Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Regional Blood Flow; Vasoconstrictor Agents | 2008 |
Activation of local chorionic villi angiotensin II levels but not angiotensin (1-7) in preeclampsia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Chorionic Villi; Female; Gene Expression; Humans; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2008 |
Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Cells, Cultured; DNA; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indicators and Reagents; Matrix Metalloproteinases; Myocytes, Cardiac; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazoles; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic; Valine; Valsartan | 2008 |
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Male; Neuroglia; Peptide Fragments; Rats; Renin-Angiotensin System; Solitary Nucleus; Tetrazoles | 2008 |
Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Carboxypeptidases A; Cell Proliferation; Fibrosis; Heart; Imidazoles; Immunohistochemistry; Leucine; Male; Membranes; Mice; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Succinates | 2008 |
Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension; Male; Myocardium; Peptide Fragments; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Time Factors | 2008 |
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis.
Topics: Adenoviridae; Angioplasty, Balloon; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Atherosclerosis; Cell Line; Cells, Cultured; Collagen; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Disease Progression; Genetic Vectors; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Time Factors; Transduction, Genetic; Up-Regulation | 2008 |
Angiotensin-(1-7) has a dual role on growth-promoting signalling pathways in rat heart in vivo by stimulating STAT3 and STAT5a/b phosphorylation and inhibiting angiotensin II-stimulated ERK1/2 and Rho kinase activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Dose-Response Relationship, Drug; Growth; Heart; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Tyrosine | 2008 |
Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Female; Hypertension; Kidney; Male; Mice; Myocardium; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Factors | 2008 |
Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Baroreflex; Biguanides; Blood Pressure; Female; Heart Rate; Male; Mice; Peptide Fragments; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Solitary Nucleus | 2008 |
Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Arteries; Cattle; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
The functional importance of the N-terminal region of human prolylcarboxypeptidase.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxypeptidases; Catalysis; Cell Line; Enzyme Stability; Humans; Peptide Fragments; Protein Conformation; Recombinant Proteins | 2008 |
MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cells, Cultured; Flavonoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Okadaic Acid; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Vanadates | 2008 |
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Vasodilator Agents | 2008 |
Angiotensin processing is partially carried out by carboxypeptidases in the rat mesenteric arterial bed perfusate.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Carboxypeptidases; In Vitro Techniques; Kinetics; Mesenteric Arteries; Peptide Fragments; Perfusion; Phenanthrolines; Protease Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Wistar; Substrate Specificity | 2008 |
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Crosses, Genetic; Heart; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Ventricular Remodeling | 2008 |
Regulation of ACE2 in cardiac myocytes and fibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Atrial Natriuretic Factor; Butadienes; Cells, Cultured; Endothelin-1; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Heart Ventricles; Losartan; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Nitriles; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction | 2008 |
The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Female; Heart; Humans; Hypertension; Male; Mice; Mice, Knockout; Models, Animal; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2008 |
Angiotensin-(1-7) enhances angiotensin II induced phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Bone Marrow Cells; Dendritic Cells; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptors, Cell Surface; RNA, Messenger | 2009 |
Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Betamethasone; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Development; Glucocorticoids; Hypertension; Kidney Tubules, Proximal; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Sheep | 2009 |
Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Cross-Sectional Studies; Female; Hemodynamics; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Peptide Fragments; Portal Vein; Propranolol; Renin; Renin-Angiotensin System; Splanchnic Circulation | 2008 |
Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Nuclear Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Signal Transduction | 2009 |
Therapeutic targets in liver transplantation: angiotensin II in nonsteatotic grafts and angiotensin-(1-7) in steatotic grafts.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Apoptosis; Fatty Liver; Graft Survival; Health; Liver Transplantation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Rats; Receptors, Angiotensin | 2009 |
Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.
Topics: Actins; Adult; Angiotensin I; Angiotensin II; Animals; Bile Ducts; Cells, Cultured; Drug Evaluation, Preclinical; Female; Hepatitis C, Chronic; Humans; Hydroxyproline; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Middle Aged; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2009 |
Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Common Bile Duct; Gene Expression Regulation, Enzymologic; Imidazoles; Leucine; Ligation; Lisinopril; Liver; Liver Cirrhosis, Experimental; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Portal Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Severity of Illness Index; Thiazepines; Time Factors; Vascular Resistance | 2009 |
[Effect of angiotensin1-7 on alpha-smooth muscle actin protein expression in rat hepatic stellate cells].
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Calcium; Cell Line; Gene Expression Regulation; Hepatic Stellate Cells; Peptide Fragments; Rats; rho-Associated Kinases; RNA, Messenger; Signal Transduction | 2009 |
Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis.
Topics: Angiotensin I; Angiotensin II; Animals; Cross-Sectional Studies; Female; Hemodynamics; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Splanchnic Circulation | 2009 |
Cell swelling, impulse conduction, and cardiac arrhythmias in the failing heart. Opposite effects of angiotensin II and angiotensin (1-7) on cell volume regulation.
Topics: Angiotensin I; Angiotensin II; Animals; Arrhythmias, Cardiac; Cardiomyopathies; Cell Size; Cells, Cultured; Cricetinae; Electrophysiology; Heart Conduction System; Heart Failure; Heart Ventricles; Hypotonic Solutions; Male; Membrane Potentials; Myocytes, Cardiac; Peptide Fragments; Pulse | 2009 |
Endothelium-dependent relaxation factor released by perivascular adipose tissue.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelium-Dependent Relaxing Factors; Immunohistochemistry; Male; Peptide Fragments; Potassium Channels; Pyridines; Rats; Rats, Wistar; Thiazepines | 2009 |
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.
Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Down-Regulation; Female; Gene Expression; Humans; Imidazoles; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stereoisomerism; Uterus | 2009 |
Acute modulation of myocardial function by angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Diastole; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Male; Myocardial Contraction; Naphthyridines; Nitroarginine; Papillary Muscles; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rabbits; Receptors, G-Protein-Coupled | 2009 |
Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Heart Rate; Hypertension; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Inbred F344 | 2009 |
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Disease Progression; Hypertension, Renovascular; Infusion Pumps, Implantable; Peptide Fragments; Rats; Rats, Transgenic; Surgical Instruments; Telemetry; Vasodilator Agents | 2009 |
Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carbon Tetrachloride Poisoning; Extracellular Signal-Regulated MAP Kinases; Gene Deletion; Hepatic Stellate Cells; Ligation; Liver Cirrhosis; Mice; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Renin-Angiotensin System | 2009 |
Gonadotropin stimulation increases the expression of angiotensin-(1--7) and MAS receptor in the rat ovary.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Female; Gonadotropins, Equine; Immunohistochemistry; Injections, Subcutaneous; Neprilysin; Ovary; Peptide Fragments; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Prolyl Oligopeptidases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger; Serine Endopeptidases; Spectrometry, Fluorescence; Superovulation; Up-Regulation | 2009 |
Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Irbesartan; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptor, Angiotensin, Type 1; RNA, Messenger; Superoxides; Tetrazoles; Time Factors; Ultrasonography; Ventricular Remodeling | 2009 |
Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Renin; RNA, Messenger; Sodium Chloride, Dietary; Ventricular Dysfunction, Left; Ventricular Remodeling | 2010 |
Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Enzyme Inhibitors; Female; Imidazoles; Kidney Cortex; Leucine; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Reactive Oxygen Species; Receptors, Angiotensin; Sheep; Time Factors | 2010 |
Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Infusion Pumps; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2010 |
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Calcium; Cardiomegaly; Cell Size; Cells, Cultured; Cyclic GMP; Hypertension; Microscopy, Confocal; Myocytes, Cardiac; NFATC Transcription Factors; Nitric Oxide; Peptide Fragments; Protein Transport; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Signal Transduction | 2010 |
Infusion of angiotensin-(1-7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Gene Expression Regulation; Glomerulonephritis; Infusion Pumps, Implantable; Infusions, Subcutaneous; Isoantibodies; Kidney; Male; Mesangial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2010 |
Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hypertension; Hypertrophy, Left Ventricular; Insulin; Insulin Resistance; Male; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
Circulating rather than cardiac angiotensin-(1-7) stimulates cardioprotection after myocardial infarction.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Bone Marrow Cells; Heart Failure; Hemodynamics; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocytes, Cardiac; Peptide Fragments; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2010 |
Simultaneous determination of angiotensins II and 1-7 by capillary zone electrophoresis in plasma and urine from hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Hypertension; Limit of Detection; Linear Models; Male; Peptide Fragments; Rats; Rats, Wistar; Temperature | 2010 |
Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Losartan; Male; Medulla Oblongata; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2010 |
Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Liver; Male; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction | 2010 |
Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Biosensing Techniques; Blood Pressure; Calcium Signaling; Catecholamines; Disease Models, Animal; Genes, Reporter; Hypertension; Losartan; Medulla Oblongata; Membrane Potentials; Microscopy, Confocal; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Tissue Culture Techniques | 2010 |
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7).
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Angiotensin I; Angiotensin II; Animals; Biomarkers; Blood Glucose; Body Weight; Cells, Cultured; Cholesterol; Insulin; Leptin; Lipid Metabolism; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Time Factors; Triglycerides; Up-Regulation | 2010 |
Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart Ventricles; Imidazoles; Leucine; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Transgenic | 2010 |
Regulation of angiotensin converting enzyme II by angiotensin peptides in human cardiofibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Fibroblasts; Humans; Mitogen-Activated Protein Kinase 3; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Up-Regulation | 2010 |
Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Chronic Disease; Disease Models, Animal; Glomerular Filtration Rate; Hematocrit; Imidazoles; Infusion Pumps; Injections, Subcutaneous; Inulin; Kidney; Kidney Diseases; Leucine; Losartan; Male; Mice; Nephrectomy; Organ Size; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Time Factors | 2010 |
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2010 |
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Kidney; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury; Urine | 2010 |
Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cadherins; Cell Differentiation; Cell Line; Epithelial Cells; Imidazoles; Kidney Tubules; Mesoderm; Models, Animal; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Angiotensin-(1-7) attenuates hyposmolarity-induced ANP secretion via the Na+-K+ pump.
Topics: Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Osmolar Concentration; Peptide Fragments; Perfusion; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Stress, Physiological; Time Factors | 2010 |
Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin-angiotensin system in inflammation.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autoantibodies; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Scleroderma, Systemic | 2010 |
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitroprusside; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autoradiography; Female; Fertilization in Vitro; Follicular Fluid; Humans; Immunohistochemistry; Iodine Radioisotopes; Middle Aged; Ovary; Ovulation Induction; Peptide Fragments; Peptidyl-Dipeptidase A; Postmenopause; Premenopause; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Tetrazoles | 2010 |
Angiotensin (1-7) receptor antagonism equalizes angiotensin II-induced hypertension in male and female spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Female; Hypertension; Kidney Cortex; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors; Vasoconstrictor Agents | 2010 |
Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Movement; Cell Proliferation; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Peptide Fragments; Phosphorylation; Receptor, Angiotensin, Type 1 | 2010 |
Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Line; Gene Expression Regulation; Membrane Potentials; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Peptide Fragments; Potassium; Protein Isoforms; Receptors, Angiotensin; Signal Transduction | 2011 |
Angiotensin II and angiotensin-(1-7) decrease sFlt1 release in normal but not preeclamptic chorionic villi: an in vitro study.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Cells, Cultured; Chorionic Villi; Down-Regulation; Female; Humans; Middle Aged; Peptide Fragments; Placenta; Placental Circulation; Placental Lactogen; Pre-Eclampsia; Pregnancy; Protein Isoforms; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Young Adult | 2010 |
Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Progression; Hypertension, Renovascular; Male; Mice; Mice, Knockout; Nitric Oxide; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Surgical Instruments; Vasomotor System | 2010 |
Enhanced angiotensin-converting enzyme 2 attenuates angiotensin II-induced collagen production via AT1 receptor-phosphoinositide 3-kinase-Akt pathway.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Kidney Failure, Chronic; Mesangial Cells; Mice; Molecular Targeted Therapy; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Transcriptional Activation | 2011 |
Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renovascular; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger | 2011 |
Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Adhesion; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Cytokines; Dietary Fats; Disease Models, Animal; Endothelial Cells; Humans; Inflammation Mediators; Losartan; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Peptide Fragments; Peptidyl-Dipeptidase A; Receptors, LDL | 2011 |
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomyopathy, Dilated; Disease Models, Animal; Enzyme Activation; Extracellular Matrix; Heart Failure; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Stress, Mechanical; Superoxides; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brain; Captopril; Cytokines; Heart; Hydralazine; Hypertension; In Vitro Techniques; Insulin; Kidney; Leptin; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Proteinuria; Rats; Rats, Inbred SHR; Ventricular Function, Left | 2011 |
Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carotid Sinus; Collagen; Denervation; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System | 2010 |
Impairment of the Plasmodium falciparum erythrocytic cycle induced by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Life Cycle Stages; Malaria, Falciparum; Peptide Fragments; Peptides; Plasmodium falciparum; Rats; Renin-Angiotensin System; Schizonts | 2011 |
Attenuating effect of angiotensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Body Weight; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Immunohistochemistry; Mesangial Cells; Mice; NADPH Oxidases; Peptide Fragments; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric | 2011 |
Chronic treatment with angiotensin-(1-7) improves renal endothelial dysfunction in apolipoproteinE-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Atherosclerosis; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Infusion Pumps, Implantable; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation | 2011 |
Purification and characterization of angiotensin converting enzyme 2 (ACE2) from murine model of mesangial cell in culture.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Cells, Cultured; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Kinetics; Mesangial Cells; Mice; Microscopy, Fluorescence; Peptide Fragments; Peptidyl-Dipeptidase A; Sequence Analysis, DNA | 2011 |
Beneficial effects of angiotensin (1-7) in diabetic rats with cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dyslipidemias; Fibrosis; Heart Ventricles; Hypertrophy, Left Ventricular; Lipids; Nitrates; Nitrites; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
Angiotensin-(1-7) induces ovulation and steroidogenesis in perfused rabbit ovaries.
Topics: Angiotensin I; Angiotensin II; Animals; Chorionic Gonadotropin; Estradiol; Female; Gonadotropins, Equine; Oocytes; Ovarian Follicle; Ovary; Ovulation; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled | 2011 |
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Endothelin-1; Enzyme Activation; Infarction, Middle Cerebral Artery; Male; Nitric Oxide Synthase Type II; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke | 2011 |
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan | 2011 |
Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Body Weight; Diabetes Mellitus; ErbB Receptors; Glucose; Hyperglycemia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinazolines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins | 2012 |
Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Chronic Disease; Consciousness; Disease Models, Animal; Heart Failure; Heart Rate; Infusions, Intraventricular; Kidney; Male; Metoprolol; Peptide Fragments; Rabbits; Sympathetic Nervous System; Vagus Nerve | 2011 |
[Influence of angiotensin-(1-7) on angiotensin II induced rat's tubular epithelial-myofibroblast transdifferentiation].
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cadherins; Cell Line; Cell Transdifferentiation; Epithelial Cells; Fibronectins; Gene Expression Regulation; Kidney Tubules; Matrix Metalloproteinase 2; Myofibroblasts; Peptide Fragments; Rats; RNA, Messenger | 2011 |
Direct renin inhibition in a rat model of chronic allograft injury.
Topics: Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fumarates; Kidney; Kidney Transplantation; Male; Models, Animal; Peptide Fragments; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Transplantation, Homologous | 2011 |
Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Enzyme Induction; Heart Failure; Humans; Male; Medulla Oblongata; Mice; Mice, Knockout; Myocardial Ischemia; Nerve Tissue Proteins; Nitric Oxide; Norepinephrine; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Reflex, Abnormal; Sympathetic Nervous System | 2011 |
The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Infusions, Subcutaneous; Kidney; Models, Animal; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstrictor Agents | 2012 |
Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma.
Topics: Adenocarcinoma; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Caco-2 Cells; Cell Cycle; Colonic Neoplasms; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intestinal Mucosa; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2012 |
Decidualized pseudopregnant rat uterus shows marked reduction in Ang II and Ang-(1-7) levels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blastocyst; Cell Polarity; Decidua; Down-Regulation; Embryo Implantation; Female; Isoenzymes; Models, Biological; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Transport; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Uterus | 2012 |
Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autoimmune Diseases; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Survival; Endoplasmic Reticulum Stress; Heart Diseases; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocarditis; Myosins; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Receptors, G-Protein-Coupled; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Tetrazoles | 2012 |
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Drug Interactions; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Myocardium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasoconstrictor Agents; Ventricular Remodeling | 2012 |
Angiotensin-(1-7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; MAP Kinase Signaling System; Mesangial Cells; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley | 2012 |
Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Heart Rate; Hypothalamus; Male; Morpholines; Neurons; Peptide Fragments; PTEN Phosphohydrolase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vanadium Compounds | 2012 |
Role of renin-angiotensin system and oxidative status on the maternal cardiovascular regulation in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Atrial Natriuretic Factor; Diabetes Mellitus; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System | 2012 |
Angiotensin-(1-7) inhibits vascular remodelling in rat jugular vein grafts via reduced ERK1/2 and p38 MAPK activity.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Blood Vessel Prosthesis; Body Weight; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hemodynamics; Infusions, Intravenous; Jugular Veins; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transplantation, Autologous | 2011 |
Angiotensin-(1-7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Collagen; Cyclooxygenase 2; DNA; Dual Specificity Phosphatase 1; Endothelin-1; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart Diseases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptide Fragments; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats; Signal Transduction | 2012 |
Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.
Topics: Allergens; Angiotensin I; Angiotensin II; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cells, Cultured; Humans; Leukocytes, Mononuclear; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Peptide Fragments; Phytohemagglutinins; Pneumonia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2012 |
Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Blood Pressure; Blotting, Western; C-Reactive Protein; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; Female; Hypertension; Immunohistochemistry; Kidney; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Characteristics; Vascular Endothelial Growth Factor A | 2012 |
Angiotensin-(1-7) suppresses the number and function of the circulating fibrocytes by upregulating endothelial nitric oxide synthase expression.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blood Cells; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Hydroxyproline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Up-Regulation | 2012 |
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
Topics: 3T3-L1 Cells; Adipocytes; Adiposity; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Estrogens; Female; Gene Expression Regulation, Enzymologic; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Risk Factors; RNA, Messenger; Sex Factors; Testosterone; Time Factors; Weight Gain | 2012 |
Modeling of angiotensin II-angiotensin-(1-7) counterbalance in disease progression in spontaneously hypertensive rats treated with/without perindopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Models, Biological; Peptide Fragments; Perindopril; Rats; Rats, Inbred SHR | 2012 |
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Losartan; MAP Kinase Signaling System; Mesangial Cells; Microscopy, Confocal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transforming Growth Factor beta1 | 2012 |
The Mas receptor mediates modulation of insulin signaling by angiotensin-(1-7).
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dyslipidemias; Fructose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GTPase-Activating Proteins; Hypertension; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction | 2012 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Hypertension, Renal; Kidney; Kidney Cortex; Male; Mass Spectrometry; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Sodium, Dietary; Spectrometry, Mass, Electrospray Ionization | 2012 |
Regulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cell Line, Transformed; Cell Line, Tumor; Choriocarcinoma; Cyclic AMP; Gene Expression Regulation; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Precursors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Secretory Pathway; Signal Transduction; Trophoblasts | 2012 |
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Collagen Type I; Collagen Type III; Desoxycorticosterone; Disease Models, Animal; Heart Rate; Heart Ventricles; Hypertension; Infusions, Intraventricular; Kidney; Lateral Ventricles; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2012 |
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Female; Imidazoles; Kidney Tubules, Proximal; Models, Animal; Natriuresis; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles | 2012 |
Central ventilatory and cardiovascular actions of angiotensin peptides in trout.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Female; Gills; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Time Factors; Trout | 2012 |
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrolysis; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Apoptosis Inducing Factor; Cell Survival; Cells, Cultured; Cytochromes c; Gene Expression Regulation; Hydrogen Peroxide; Kidney Tubules; Membrane Potential, Mitochondrial; Mitochondria; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Rats; Signal Transduction; Superoxides | 2012 |
Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cerebrovascular Circulation; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2012 |
Inhibition of angiotensin II-induced contraction of human airway smooth muscle cells by angiotensin-(1-7) via downregulation of the RhoA/ROCK2 signaling pathway.
Topics: Actins; Angiotensin I; Angiotensin II; Bronchi; Cells, Cultured; Humans; Muscle Contraction; Myocytes, Smooth Muscle; Peptide Fragments; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2012 |
Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation; Hypertension; Ion Channels; JNK Mitogen-Activated Protein Kinases; Male; Medulla Oblongata; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oligonucleotides, Antisense; Oxidative Stress; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Signal Transduction; Uncoupling Protein 2 | 2012 |
Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Collagen; Collagen Type I; Collagen Type III; Gene Expression Regulation; Heart; Hypertrophy, Left Ventricular; Male; Mice; Mice, Knockout; Peptide Fragments; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Remodeling | 2012 |
Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diet, High-Fat; Dietary Carbohydrates; Energy Intake; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Homeostasis; Insulin Resistance; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Myoblasts; Myogenic Regulatory Factors; Peptide Fragments; Peptidyl-Dipeptidase A | 2013 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance | 2012 |
Angiotensin-(1-7) treatment ameliorates angiotensin II-induced apoptosis of human umbilical vein endothelial cells.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blotting, Western; Caspase 3; Cell Culture Techniques; Dose-Response Relationship, Drug; Endothelial Cells; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Scavenger Receptors, Class E; Up-Regulation | 2012 |
[Angiotensin (1-7) inhibits angiotensin II-stimulated expression of connective tissue growth factor mRNA in hepatic stellate cells].
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Connective Tissue Growth Factor; Hepatic Stellate Cells; Humans; Peptide Fragments; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction | 2012 |
Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Endothelium, Vascular; In Situ Hybridization; Liver; Liver Circulation; Liver Cirrhosis; Male; Methoxamine; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Vasoconstrictor Agents | 2013 |
Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Hypertension; Male; Malondialdehyde; Neurons; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Adenine; Afferent Pathways; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Body Weight; Bucladesine; Cyclic AMP; Heart; Hypertension, Renovascular; Kidney; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reflex; Sympathetic Nervous System; Thionucleotides | 2012 |
Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging.
Topics: Acetylcholine; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Male; Mice; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Vasculitis; Vasodilation; Vasodilator Agents | 2012 |
Interaction between TGF-β and ACE2-Ang-(1-7)-Mas pathway in high glucose-cultured NRK-52E cells.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Benzamides; Cells, Cultured; Chromones; Dioxoles; Fibronectins; Gene Expression Regulation; Glucose; Janus Kinase 2; LLC-PK1 Cells; Molecular Sequence Data; Morpholines; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, G-Protein-Coupled; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Swine; Transcription, Genetic; Transforming Growth Factor beta; Tyrphostins | 2013 |
Angiotensin-(1-7) regulates Angiotensin II-induced VCAM-1 expression on vascular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; Cell Line; Endothelium, Vascular; Humans; NF-kappa B; Peptide Fragments; Protein Transport; Receptors, G-Protein-Coupled; Vascular Cell Adhesion Molecule-1 | 2013 |
Angiotensin (1-7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Adhesion; Chemokine CCL2; DNA; Endothelial Cells; Female; Humans; Inflammation; Male; NF-kappa B; Peptide Fragments; Rabbits; Scavenger Receptors, Class E; Vascular Cell Adhesion Molecule-1 | 2013 |
Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Heart; Heart Rate; Hypertension, Renovascular; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Reflex; Sympathetic Nervous System; Systole | 2012 |
Angiotensin-(1-7) inhibits vascular calcification in rats.
Topics: Actins; Alkaline Phosphatase; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Calcium-Binding Proteins; Calponins; Cholecalciferol; Cytoskeletal Proteins; Disease Models, Animal; Gene Expression Regulation; Male; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Nicotine; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Vascular Calcification | 2013 |
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.
Topics: Angiotensin I; Angiotensin II; Animals; Bleeding Time; Blood Platelets; Bone Marrow Transplantation; Cyclic AMP; Cyclic GMP; Epoprostenol; Immunoblotting; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Thrombosis; Time Factors | 2013 |
Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Dipeptides; Imidazoles; Kidney; Leucine; Male; Mice; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Diet composition modulates expression of sirtuins and renin-angiotensin system components in adipose tissue.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cholesterol, HDL; Diet, High-Fat; Dietary Fats; Dietary Proteins; Dietary Sucrose; Glucose; Lipids; Male; Mice; Mice, Inbred Strains; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sirtuins; Triglycerides | 2013 |
Up-regulation of components of the renin-angiotensin system in liver fibrosis in the rat induced by CCL₄.
Topics: Angiotensin I; Angiotensin II; Animals; Blotting, Western; Carbon Tetrachloride; Gene Expression Regulation, Enzymologic; Liver Cirrhosis; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; RNA; Statistics, Nonparametric; Up-Regulation | 2013 |
The balance between human maternal plasma angiotensin II and angiotensin 1-7 levels in early gestation pregnancy is influenced by fetal sex.
Topics: Angiotensin I; Angiotensin II; C-Reactive Protein; Female; Fetus; Humans; Male; Maternal Welfare; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Renin-Angiotensin System; Sex Characteristics | 2014 |
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Humans; Male; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2013 |
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Tetrazoles | 2013 |
Complete blockade of the vasorelaxant effects of angiotensin-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Human Umbilical Vein Endothelial Cells; Humans; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation; Vasodilator Agents | 2013 |
Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Autophagy; Blood Pressure; Brain; Hypertension; Imidazoles; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mesenteric Arteries; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2013 |
Role of angiotensin II and angiotensin-(1-7) in diabetes-induced oxidative DNA damage in the corpus cavernosum.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; DNA Damage; Male; Oxidative Stress; Penis; Peptide Fragments; Proto-Oncogene Mas; Random Allocation; Rats; Rats, Wistar; Signal Transduction | 2013 |
Prolyl carboxypeptidase: a forgotten kidney angiotensinase. Focus on "Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry".
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Male; Peptide Fragments; Peptidyl-Dipeptidase A | 2013 |
Abrogation of ER stress-induced apoptosis of alveolar epithelial cells by angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Antineoplastic Agents; Apoptosis; Autocrine Communication; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Leupeptins; Peptide Fragments; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein C; Receptors, Angiotensin; Signal Transduction; Vasoconstrictor Agents | 2013 |
Ang(1-7) treatment attenuates β-cell dysfunction by improving pancreatic microcirculation in a rat model of Type 2 diabetes.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Pancreas; Peptide Fragments; Rats; Rats, Wistar | 2013 |
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Naphthalenes; Neointima; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resorcinols; Severity of Illness Index; Time Factors; Vasodilation | 2013 |
Antinociceptive response in transgenic mice expressing rat tonin.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Behavior, Animal; Disease Models, Animal; Losartan; Male; Mice; Mice, Transgenic; Nociception; Nociceptive Pain; Pain Measurement; Peptide Fragments; Rats; Receptors, G-Protein-Coupled; Tissue Kallikreins | 2013 |
Fetal sex and the circulating renin-angiotensin system during early gestation in women who later develop preeclampsia or gestational hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Biomarkers; Blood Pressure; Case-Control Studies; Female; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System; Risk Assessment; Risk Factors; Sex Determination Analysis; Sex Factors; Ultrasonography, Doppler; Ultrasonography, Prenatal; Young Adult | 2014 |
The renin angiotensin system regulates Kupffer cells in colorectal liver metastases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colorectal Neoplasms; Disease Models, Animal; Gadolinium; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Renin-Angiotensin System | 2013 |
AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chronic Disease; Cytokines; Disease Models, Animal; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Mice; Mice, Inbred BALB C; Molecular Mimicry; Ovalbumin; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Veins; Receptors, G-Protein-Coupled; Time Factors | 2013 |
Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Lipopolysaccharides; Losartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Vasodilator Agents | 2013 |
Protective effects of angiotensin-(1-7) administrated with an angiotensin-receptor blocker in a rat model of chronic kidney disease.
Topics: Angiopoietins; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibronectins; Losartan; Male; Nephrectomy; Peptide Fragments; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Receptor, TIE-2; Renal Insufficiency, Chronic; Systole | 2013 |
Angiotensin-(1-7) protects from experimental acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electric Impedance; Endothelial Cells; Hemodynamics; Imidazoles; Irbesartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Respiratory Mechanics; Tetrazoles | 2013 |
The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Benzopyrans; Down-Regulation; Drug Therapy, Combination; Ethanolamines; Female; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Nebivolol; Peptide Fragments; Renin-Angiotensin System; Vasodilator Agents | 2013 |
The effects of angiotensin II and angiotensin-(1-7) in the rostral ventrolateral medulla of rats on stress-induced hypertension.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Gene Expression Regulation; Heart Rate; Hypertension; Male; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stress, Psychological | 2013 |
Angiotensin (1-7) contributes to nitric oxide tonic inhibition of vasopressin release during hemorrhagic shock in acute ethanol intoxicated rodents.
Topics: Alcoholic Intoxication; Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Enzyme Inhibitors; Hemodynamics; Injections, Intraventricular; Male; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Shock, Hemorrhagic; Up-Regulation | 2013 |
Role of angiotensin-(1-7) in gastroprotection against stress-induced ulcerogenesis. The involvement of mas receptor, nitric oxide, prostaglandins, and sensory neuropeptides.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Ulcer Agents; Capsaicin; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Denervation; Enzyme Inhibitors; Gastric Mucosa; Interleukin-1beta; Male; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Regional Blood Flow; Renin-Angiotensin System; Sensory Receptor Cells; Stomach; Stomach Ulcer; Tumor Necrosis Factor-alpha | 2013 |
Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Cardiomegaly; Cardiotonic Agents; Collagen; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Gene Expression Regulation; Irbesartan; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; PPAR alpha; PPAR delta; PPAR gamma; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Tetrazoles; Transforming Growth Factor beta | 2013 |
Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cattle; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Peptide Fragments; Vasodilation | 2013 |
Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; bcl-X Protein; Bleomycin; Cells, Cultured; Collagen Type I; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Infusions, Subcutaneous; Lung; Male; MAP Kinase Signaling System; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pneumonia; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2014 |
[Expression and significance of ACE2-Ang-(1-7)-Mas axis in the endometrium of patients with polycystic ovary syndrome].
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Case-Control Studies; Endometrium; Female; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Polycystic Ovary Syndrome; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Young Adult | 2013 |
Angiotensin 1-7 improves insulin sensitivity by increasing skeletal muscle glucose uptake in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Glucose; Insulin Resistance; Male; Muscle, Skeletal; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2014 |
Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthalenes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles; Receptors, G-Protein-Coupled; Renal Circulation; Vascular Resistance | 2014 |
Angiotensin (1-7) protects against stress-induced gastric lesions in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cold Temperature; Corticosterone; H(+)-K(+)-Exchanging ATPase; Infusions, Intraventricular; Male; Norepinephrine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 2014 |
Angiotensin-converting enzyme (ACE and ACE2) imbalance correlates with the severity of cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Amylases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Genotype; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Pancreas; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Severity of Illness Index; Time Factors | 2014 |
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Autocrine Communication; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Male; Myocardium; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Ventricular Remodeling | 2014 |
Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diminazene; Disease Models, Animal; Glutamyl Aminopeptidase; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Xanthones | 2014 |
Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Enzyme Inhibitors; Glutamyl Aminopeptidase; Kinetics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Tandem Mass Spectrometry; Ventricular Remodeling | 2014 |
Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Brain; Brain Edema; Brain Ischemia; Cell Death; Female; Glucose; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Male; Membrane Glycoproteins; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Reactive Oxygen Species; Stroke; Tissue Culture Techniques | 2014 |
The Ang-(1-7)/Mas-1 axis attenuates the expression and signalling of TGF-β1 induced by AngII in mouse skeletal muscle.
Topics: Angiotensin I; Angiotensin II; Animals; Mice; Mice, Inbred C57BL; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Smad4 Protein; Transforming Growth Factor beta1 | 2014 |
Ulinastatin activates the renin-angiotensin system to ameliorate the pathophysiology of severe acute pancreatitis.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Ceruletide; Disease Models, Animal; Gene Expression; Glycoproteins; Lipopolysaccharides; Mice, Inbred C57BL; Molecular Targeted Therapy; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Prospective Studies; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Severity of Illness Index | 2014 |
Angiotensin-(1-7) attenuates angiotensin II-induced signalling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Activation; Fibroblasts; Mitogen-Activated Protein Kinases; Myocardium; Peptide Fragments; Phosphorylation; Primary Cell Culture; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases | 2014 |
Female spontaneously hypertensive rats are more dependent on ANG (1-7) to mediate effects of low-dose AT1 receptor blockade than males.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Membrane Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sex Factors; Tetrazoles | 2014 |
Angiotensin-(1-7) recruits muscle microvasculature and enhances insulin's metabolic action via mas receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Blood Flow Velocity; Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Glucose; Hindlimb; Hypoglycemic Agents; In Vitro Techniques; Infusions, Intravenous; Insulin; Male; Microvessels; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Regional Blood Flow; Vasodilation | 2014 |
Angiotensin-(1-7) and angiotensin Ⅱ induce the transdifferentiation of human endometrial epithelial cells in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Cadherins; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Collagen Type I; Endometrium; Epithelial Cells; Female; Fibronectins; Humans; Immunohistochemistry; Peptide Fragments | 2014 |
Angiotensin (1-7) prevents angiotensin II-induced nociceptive behaviour via inhibition of p38 MAPK phosphorylation mediated through spinal Mas receptors in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Behavior, Animal; Injections, Spinal; Mice; Nociceptive Pain; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Spinal Cord | 2014 |
Ang (1-7) protects islet endothelial cells from palmitate-induced apoptosis by AKT, eNOS, p38 MAPK, and JNK pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Cell Line, Transformed; Endothelium, Vascular; Enzyme Activation; Fatty Acids, Nonesterified; Islets of Langerhans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Microvessels; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Peptide Fragments; Protective Agents; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction | 2014 |
Activation of the ACE2/Ang-(1-7)/Mas pathway reduces oxygen-glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Brain; Brain Edema; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Cerebral Cortex; Glucose; Hypoxia; Membrane Glycoproteins; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Stroke; Tissue Culture Techniques | 2014 |
Angiotensin II and 1-7 during aging in Metabolic Syndrome rats. Expression of AT1, AT2 and Mas receptors in abdominal white adipose tissue.
Topics: Adipose Tissue, White; Aging; Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Humans; Hypertension; Metabolic Syndrome; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2014 |
Angiotensin-(1-7) induces cerebral ischaemic tolerance by promoting brain angiogenesis in a Mas/eNOS-dependent pathway.
Topics: Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Animals; Brain; Cerebrovascular Circulation; Endostatins; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Ornithine; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2014 |
Estrogen regulation of the brain renin-angiotensin system in protection against angiotensin II-induced sensitization of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Brain; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Hypertension; Infusions, Intraventricular; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger; Sex Factors; Telemetry; Time Factors | 2014 |
Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cattle; Cell Line; Cell Nucleus; Epithelial Cells; Kidney; Peptide Fragments; Prorenin Receptor; Protease Inhibitors; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Sheep; Time Factors | 2015 |
Role of Mas receptor in renal blood flow response to angiotensin (1-7) in male and female rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Kidney; Male; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renal Circulation; Renin-Angiotensin System; Sex Factors | 2014 |
Fetal and maternal angiotensin (1-7) are associated with preterm birth.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Fetal Blood; Fetus; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Peptide Fragments; Pre-Eclampsia; Pregnancy; Premature Birth; Prospective Studies; Renin-Angiotensin System; Risk Factors; Term Birth | 2014 |
[Effect of tanshinone II(A) on expression of different components in renin-angiotensin system of left ventricles of hypertensive rats].
Topics: Abietanes; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Heart Ventricles; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2014 |
Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Male; Mesangial Cells; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Valsartan; Vascular Endothelial Growth Factor A | 2015 |
Angiotensin-(1-7) prevents angiotensin II-induced fibrosis in cremaster microvessels.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Chronic Disease; Connective Tissue Growth Factor; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Rats; Rats, Inbred Lew; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Vasoconstrictor Agents | 2015 |
Angiotensin-(1-7) attenuates damage to podocytes induced by preeclamptic serum through MAPK pathways.
Topics: Actins; Adult; Angiotensin I; Angiotensin II; Apoptosis; Cell Survival; Female; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Podocytes; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2014 |
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
MSCs modified with ACE2 restore endothelial function following LPS challenge by inhibiting the activation of RAS.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Endothelial Cells; Genetic Therapy; HEK293 Cells; Humans; Lipopolysaccharides; Mesenchymal Stem Cells; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2015 |
Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Male; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2015 |
The angiotensin-(1-7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Disease Models, Animal; Immunoblotting; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Peptide Fragments; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2015 |
Changes in levels of angiotensin II and its receptors in a model of inverted stress-induced cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Female; Myocardium; Peptide Fragments; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Stress, Physiological | 2014 |
Angiotensin-(1-7) modulates angiotensin II-induced vasoconstriction in human mammary artery.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Endothelium, Vascular; Female; Humans; Losartan; Male; Mammary Arteries; Middle Aged; Myocytes, Smooth Muscle; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Vasoconstriction | 2014 |
Hyperbaric oxygenation modulates vascular reactivity to angiotensin-(1-7) in diabetic rats: potential role of epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Enzyme Induction; Enzyme Inhibitors; Hyperbaric Oxygenation; Male; Oxidative Stress; Peptide Fragments; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2015 |
Lack of renoprotective effect of chronic intravenous angiotensin-(1-7) or angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis.
Topics: Angiotensin I; Angiotensin II; Animals; Drug Administration Schedule; Glomerulosclerosis, Focal Segmental; HEK293 Cells; Humans; Hypertension; Injections, Intravenous; Male; Nephrectomy; Peptide Fragments; Podocytes; Radioligand Assay; Rats; Treatment Failure | 2014 |
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 1; Fibrosis; Gene Expression Regulation; Histological Techniques; Hypertension; Immunohistochemistry; Injections, Subcutaneous; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled | 2015 |
Esophagoprotective activity of angiotensin-(1-7) in experimental model of acute reflux esophagitis. Evidence for the role of nitric oxide, sensory nerves, hypoxia-inducible factor-1alpha and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-1beta; Male; Mucous Membrane; Nitric Oxide; Peptide Fragments; Protective Agents; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptors, G-Protein-Coupled; Regional Blood Flow; RNA, Messenger; Sensory Receptor Cells; Tumor Necrosis Factor-alpha | 2014 |
Ang (1-7) is a modulator of the vasoconstrictor actions of Ang I and Ang II.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; In Vitro Techniques; Male; Myocardial Infarction; Myocardium; Peptide Fragments; Rats, Wistar; Vasoconstrictor Agents | 2015 |
The effect of angiotensin-(1-7) in mouse unilateral ureteral obstruction.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Fibronectins; Male; Mice; Muscle, Smooth; Peptide Fragments; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 2015 |
Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-κB pathways.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Cells, Cultured; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; MAP Kinase Signaling System; Microvessels; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction | 2015 |
The association of renin-angiotensin system genes with the progression of hepatocellular carcinoma.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antigens, CD34; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Gene Expression Regulation, Neoplastic; Humans; Liver Cirrhosis; Liver Neoplasms; Peptide Fragments; Peptidyl-Dipeptidase A; Prognosis; Reference Values; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2015 |
ACE2 and Ang-(1-7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Gene Transfer Techniques; Humans; In Vitro Techniques; Inflammation; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
Functional and molecular evidence for expression of the renin angiotensin system and ADAM17-mediated ACE2 shedding in COS7 cells.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Base Sequence; Chlorocebus aethiops; COS Cells; Molecular Sequence Data; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Transcription, Genetic; Transfection | 2015 |
Angiotensin-(1-7) protects against the development of aneurysmal subarachnoid hemorrhage in mice.
Topics: Aneurysm, Ruptured; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Brain; Cerebral Arteries; Cytokines; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 2; RNA, Messenger; Subarachnoid Hemorrhage | 2015 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
Angiotensin-(1-7) stimulates cholesterol efflux from angiotensin II-treated cholesterol-loaded THP-1 macrophages through the suppression of p38 and c-Jun N-terminal kinase signaling.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cholesterol; Gene Expression Regulation, Enzymologic; Humans; JNK Mitogen-Activated Protein Kinases; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; PPAR gamma; Renin-Angiotensin System; RNA, Messenger | 2015 |
Downregulation of the vascular renin-angiotensin system by aerobic training - focus on the balance between vasoconstrictor and vasodilator axes - .
Topics: Aerobiosis; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Femoral Artery; Kidney; Male; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin-Angiotensin System; Running; Vasoconstriction; Vasodilation | 2015 |
Development of a sensitive, accurate and robust liquid chromatography/mass spectrometric method for profiling of angiotensin peptides in plasma and its application for atherosclerotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Apolipoproteins E; Atherosclerosis; Chromatography, Liquid; Mass Spectrometry; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Receptors, LDL | 2015 |
Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Humans; Male; Mice; Mice, Inbred C57BL; Myocardium; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Signal Transduction | 2015 |
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Benzoates; Diet; Energy Intake; Energy Metabolism; Insulin Resistance; Leptin; Male; Obesity; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Telmisartan; Weight Gain; Weight Loss | 2015 |
Angiotensin-(1-7) Attenuates Angiotensin II-Induced ICAM-1, VCAM-1, and MCP-1 Expression via the MAS Receptor Through Suppression of P38 and NF-κB Pathways in HUVECs.
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Chemokine CCL2; Human Umbilical Vein Endothelial Cells; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cytochrome P-450 Enzyme System; Disease Progression; Enzyme Inhibitors; Epoxide Hydrolases; Fatty Acids, Monounsaturated; Female; Fistula; Heart Failure; Heart Rate; Hemodynamics; Kidney; Male; Peptide Fragments; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Solubility; Time Factors; Vena Cava, Inferior | 2015 |
Intracellular angiotensin (1-7) increases the inward calcium current in cardiomyocytes. On the role of PKA activation.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Heart Ventricles; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Inbred WKY | 2015 |
Activation of angiotensin-(1-7)/Mas axis in the brain lowers blood pressure and attenuates cardiac remodeling in hypertensive transgenic (mRen2)27 rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Heart; Heart Rate; Hypertension; Male; Myocardium; Peptide Fragments; Rats, Sprague-Dawley; Rats, Transgenic; Renin-Angiotensin System; RNA, Messenger | 2015 |
Angiotensin (1-7), small but complicated, needs more exercise.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Male; Peptide Fragments; Physical Conditioning, Animal; Renal Artery; Renin-Angiotensin System | 2015 |
Angiotensin II type 1 receptor-associated protein plays a role in regulating the local renin-angiotensin system in HSC-T6 cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Peptide Fragments; Rats; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger | 2015 |
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzoates; Disease Models, Animal; Drug Evaluation, Preclinical; Epoxide Hydrolases; Epoxy Compounds; Heart Failure; Kidney; Male; Myocardium; Peptide Fragments; Random Allocation; Rats; Renal Insufficiency; Renin-Angiotensin System; Ultrasonography; Urea | 2015 |
Angiotensin-(1-7) counteracts angiotensin II-induced dysfunction in cerebral endothelial cells via modulating Nox2/ROS and PI3K/NO pathways.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blotting, Western; Brain; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Humans; Microvessels; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Vasoconstrictor Agents; Vasodilator Agents | 2015 |
Baicalin attenuates angiotensin II-induced endothelial dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Flavonoids; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Tissue Culture Techniques; Vasodilation | 2015 |
Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue.
Topics: Adult; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Gingiva; Humans; Inflammation; Male; Middle Aged; Peptide Fragments; Periodontitis; Periodontium; Rats, Wistar; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Young Adult | 2015 |
Long-Term Regulation of the Local Renin-Angiotensin System in the Myocardium of Spontaneously Hypertensive Rats by Feeding Bioactive Peptides Derived from Spirulina platensis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Myocardium; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spirulina | 2015 |
Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Gene Deletion; Humans; Inflammation; Kidney; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Signal Transduction; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Angiotensin-(1-7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Intracranial Hemorrhages; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Wound Healing | 2015 |
ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antigens, CD34; Cell Adhesion; Cell Movement; Cell Proliferation; Diminazene; Humans; Leukocytes, Mononuclear; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents; Wound Healing; Xanthones | 2015 |
Differential control of vasomotion by angiotensins in the rostral ventrolateral medulla of hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Heart Rate; Male; Medulla Oblongata; Mesenteric Arteries; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Vascular Resistance | 2015 |
[Telmisartan reduces retina vessel endothelial cell apoptosis via upregulating retinal ACE2-Ang-(1-7)-Mas axis in spontaneous hypertensive rats].
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Benzimidazoles; Benzoates; Blood Pressure; Endothelial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Retina; Systole; Telmisartan; Up-Regulation | 2015 |
Angiotensin-(1-7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Drug Interactions; Hypertension, Renovascular; Losartan; Male; Medulla Oblongata; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; Treatment Outcome | 2015 |
Effect of angiotensin-(1-7) and angiotensin II on the proliferation and activation of human endometrial stromal cells in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Cell Proliferation; Collagen Type I; Endometrium; Female; Fibronectins; Humans; Insulin-Like Growth Factor I; Peptide Fragments; Stromal Cells; Transforming Growth Factor beta1 | 2015 |
Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Line; Kidney; Kidney Diseases; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2015 |
The effect of angiotensin-converting enzyme inhibition throughout a superovulation protocol in ewes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Embryo, Nonmammalian; Enalapril; Estradiol; Female; Ovulation; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Sheep; Superovulation | 2015 |
Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelium; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Tunicamycin | 2015 |
Osthole Alleviates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/Angiotensin-(1-7) Axis and Decreasing Inflammation Responses in Rats.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Coumarins; Cytokines; Edema; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2016 |
Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Chromatography, High Pressure Liquid; Citrate (si)-Synthase; Hypertension; Male; Medulla Oblongata; Oxidative Stress; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction | 2016 |
The renin-angiotensin system and its vasoactive metabolite angiotensin-(1-7) in the mechanism of the healing of preexisting gastric ulcers. The involvement of Mas receptors, nitric oxide, prostaglandins and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cytokines; Enzyme Inhibitors; Gastric Mucosa; Imidazoles; Indomethacin; Interleukin-1beta; Lisinopril; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Renal hemodynamics and renin-angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Case-Control Studies; Enzyme Inhibitors; Essential Hypertension; Female; Fibromuscular Dysplasia; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renovascular; Male; Microvessels; Middle Aged; Nitric Oxide Synthase; Peptide Fragments; Renal Artery; Renal Circulation; Renin; Renin-Angiotensin System; Sex Factors | 2016 |
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aortic Coarctation; Captopril; Catalase; Clofibrate; Drug Synergism; Heart Ventricles; Hypertension; Lipid Peroxidation; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; PPAR alpha; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Superoxide Dismutase; Vasodilation | 2016 |
Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.
Topics: Angiotensin I; Angiotensin II; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Epithelial Cells; Humans; Hydrolysis; Kidney; Oligopeptides; Peptide Fragments; Reactive Oxygen Species | 2016 |
Serum angiotensin-converting enzyme 2 concentration and angiotensin-(1-7) concentration in patients with acute heart failure patients requiring emergency hospitalization.
Topics: Acute Disease; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Blood Pressure; Case-Control Studies; Emergencies; Female; Heart Failure; Hospitalization; Humans; Japan; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Regression Analysis; Renin; Renin-Angiotensin System | 2017 |
Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Albuminuria; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP1A1; Hypertension, Malignant; Indoles; Kidney; Male; Peptide Fragments; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Time Factors | 2016 |
Imbalance between angiotensin II and angiotensin-(1-7) in human coronary atherosclerosis.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Peptide Fragments; Tumor Necrosis Factor-alpha | 2016 |
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Epithelial-Mesenchymal Transition; Gene Expression; Hepatocytes; Humans; Hydrogen Peroxide; Inflammasomes; Interleukin-1beta; Liver Cirrhosis; Male; Mice; NADPH Oxidase 4; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Rats, Wistar; Signal Transduction; Smad Proteins | 2016 |
Neuroinflammatory mechanisms of hypertension: potential therapeutic implications.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cytokines; Humans; Hypertension; Inflammation; Lipopolysaccharides; Microglia; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin; Toll-Like Receptor 4 | 2016 |
The kinetics of angiotensin-I metabolism in human carotid atheroma: An emerging role for angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Carotid Artery Diseases; Chromatography, High Pressure Liquid; Disease Progression; Humans; Mass Spectrometry; Peptide Fragments; Plaque, Atherosclerotic; Time Factors | 2016 |
Renin-angiotensin system in ventilator-induced diaphragmatic dysfunction: Potential protective role of Angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cell Membrane; Diaphragm; Humans; Insulin-Like Growth Factor I; Mice; Models, Theoretical; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; Peptide Fragments; Rats; Renin-Angiotensin System; Respiration, Artificial | 2016 |
Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm.
Topics: Adolescent; Adrenal Cortex Hormones; Angiotensin I; Angiotensin II; Cohort Studies; Female; Fetal Organ Maturity; Humans; Infant, Newborn; Infant, Premature; Male; Peptide Fragments; Pregnancy; Prenatal Exposure Delayed Effects; Renin; Renin-Angiotensin System | 2017 |
Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney.
Topics: Aminobutyrates; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Biopsy; Biphenyl Compounds; Female; Gene Expression; Humans; Immunohistochemistry; Kidney; Kidney Cortex; Mice; Mice, Knockout; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2016 |
A Novel Mechanism of Action for Angiotensin-(1-7) via the Angiotensin Type 1 Receptor.
Topics: Angiotensin I; Angiotensin II; Humans; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2016 |
Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Abdominal; beta-Arrestins; Cardiotonic Agents; Cells, Cultured; HEK293 Cells; Humans; Muscles; Peptide Fragments; Phenylephrine; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction; Vasoconstriction | 2016 |
The Interplay between the Renin Angiotensin System and Pacing Postconditioning Induced Cardiac Protection.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Cardiac Pacing, Artificial; Heart; Hemodynamics; Irbesartan; Male; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 2016 |
Chymase-dependent production of angiotensin II: an old enzyme in old hearts.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Chymases; Enzyme-Linked Immunosorbent Assay; Myocardium; NADPH Oxidases; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Superoxides | 2017 |
Adhesion ability of angiotensin II with model membranes.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Binding Sites; Histidine; Humans; Membranes; Molecular Weight; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System | 2017 |
Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Angiotensin I; Angiotensin II; Apolipoproteins E; Autopsy; Brain; Case-Control Studies; Cohort Studies; Female; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Single Nucleotide; Statistics as Topic; tau Proteins | 2016 |
Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Estradiol; Estrogens; Exercise Therapy; Humans; Hypertension; Ovariectomy; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2017 |
Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen Type I; Exenatide; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred BALB C; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ureteral Obstruction; Venoms | 2016 |
Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoantigens; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Kidney; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Time Factors | 2017 |
Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelial Cells; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Male; Middle Cerebral Artery; Neovascularization, Physiologic; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2017 |
Vascular Reactivity of Isolated Aorta to Study the Angiotensin-(1-7) Actions.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Aorta; In Vitro Techniques; Mice; Peptide Fragments; Phenylephrine; Rats; Vasodilation; Vasodilator Agents | 2017 |
Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carboxypeptidases; Kidney; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Mice; Mice, Mutant Strains; Myocardium; Peptide Fragments | 2017 |
Angiotensin II/Angiotensin (1-7) ratio and 24-h blood pressure throughout the menstrual cycle and in women using oral contraceptives.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estradiol; Female; Humans; Menstrual Cycle; Peptide Fragments; Progesterone; Renin-Angiotensin System; Young Adult | 2017 |
Angiotensin-(1-7) regulates angiotensin II-induced matrix metalloproteinase-8 in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Humans; Matrix Metalloproteinase 8; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Plaque, Atherosclerotic; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Time Factors | 2017 |
Chronic overexpression of angiotensin-(1-7) in rats reduces cardiac reactivity to acute stress and dampens anxious behavior.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Anxiety; Heart Rate; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2017 |
A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Fluorometry; HEK293 Cells; Humans; Immunoassay; Intercellular Signaling Peptides and Proteins; Kidney; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylalanine; Substrate Specificity | 2017 |
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac hypertrophy via a Sirt3-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Cardiotonic Agents; Cell Size; Fibrosis; Male; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Sirtuins; Superoxide Dismutase | 2017 |
The ACE-2/Ang1-7/Mas cascade enhances bone structure and metabolism following angiotensin-II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Female; Femur; Losartan; Minerals; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
Anti-inflammatory action of angiotensin 1-7 in experimental colitis may be mediated through modulation of serum cytokines/chemokines and immune cell functions.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Movement; Chemokines; Chemotaxis; Colitis; Colon; Cytokines; Dextran Sulfate; Immunity, Cellular; Immunomodulation; Mice; Mice, Inbred BALB C; Models, Animal; Neutrophils; Peptide Fragments; Renin-Angiotensin System; Superoxides | 2017 |
Reduced anxiety-like behavior in transgenic rats with chronically overproduction of angiotensin-(1-7): Role of the Mas receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Anxiety; Behavior, Animal; Imidazoles; Peptide Fragments; Pyridines; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Captopril; Delayed-Action Preparations; Female; Femur; Humans; Osteolysis; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Spectrophotometry, Atomic; X-Ray Microtomography | 2017 |
Exercise training modulates the hepatic renin-angiotensin system in fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Fatty Liver; Fructose; Gluconeogenesis; Interleukin-6; Lipid Metabolism; Liver; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2017 |
Angiotensin 1-7 inhibits angiotensin II-stimulated head and neck cancer progression.
Topics: Angiotensin I; Angiotensin II; Cell Culture Techniques; Cell Movement; Disease Progression; Fibroblasts; Head and Neck Neoplasms; Humans; Immunoblotting; Peptide Fragments; Polymerase Chain Reaction; Renin-Angiotensin System; Signal Transduction; Transfection; Tumor Cells, Cultured | 2017 |
The ACE2-Ang (1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen; Fibrosis; Heart Function Tests; Immunohistochemistry; Male; Myocardial Infarction; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Ventricular Dysfunction, Left; Ventricular Remodeling | 2017 |
Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7.
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Carotid Arteries; Female; Interleukin-6; Male; Mice; NF-kappa B; Oxidative Stress; Peptide Fragments; PPAR gamma; Pyridines; Renin-Angiotensin System; Vascular Diseases; Vasoconstrictor Agents; Vasodilation | 2017 |
Angiotensin‑(1‑7) attenuates caerulein‑induced pancreatic acinar cell apoptosis.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Ceruletide; Mice; Pancreas; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2017 |
Vasodilator Effect of Angiotensin-(1-7) on Vascular Coronary Bed of Rats: Role of Mas, ACE and ACE2.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Vessels; Heart; Humans; In Vitro Techniques; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Vasodilation; Vasodilator Agents | 2017 |
BML-111 equilibrated ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis to protect hepatic fibrosis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Down-Regulation; Heptanoic Acids; Liver Cirrhosis; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Up-Regulation | 2017 |
Angiotensin-(1-7) in Paraventricular Nucleus Contributes to the Enhanced Cardiac Sympathetic Afferent Reflex and Sympathetic Activity in Chronic Heart Failure Rats.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Capsaicin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Heart Failure; Hemodynamics; Kidney; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Signal Transduction; Spin Labels; Superoxides; Sympathetic Nervous System | 2017 |
Intrarenal Mas and AT
Topics: Anesthesia, General; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diet, Sodium-Restricted; Glomerular Filtration Rate; Hemodynamics; Infusions, Parenteral; Kidney; Losartan; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renal Circulation; Renal Elimination; Renin-Angiotensin System; Signal Transduction; Sodium, Dietary | 2017 |
Angiotensin 1-7 in the rostro-ventrolateral medulla increases blood pressure and splanchnic sympathetic nerve activity in anesthetized rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Angiotensin I; Angiotensin II; Animals; Astrocytes; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats, Sprague-Dawley; Receptors, Glutamate; Splanchnic Nerves; Sympathetic Nervous System; Sympatholytics; Sympathomimetics | 2018 |
Mir-21 Mediates the Inhibitory Effect of Ang (1-7) on AngII-induced NLRP3 Inflammasome Activation by Targeting Spry1 in lung fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Bleomycin; Cells, Cultured; Collagen Type I; Fibroblasts; Inflammasomes; Lung; Male; MAP Kinase Signaling System; MicroRNAs; Nerve Tissue Proteins; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Peptide Hormones; Pulmonary Fibrosis; Rats; Rats, Wistar; Signal Transduction | 2017 |
Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Astrocytes; Case-Control Studies; Cell Nucleus; Cells, Cultured; Dopaminergic Neurons; Gene Deletion; Haplorhini; Male; Mesencephalon; Microglia; Mitochondria; Models, Biological; Neuroprotection; Oxidative Stress; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Nitrogen Species; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Rodentia; Signal Transduction; Substantia Nigra | 2018 |
Obligatory Metabolism of Angiotensin II to Angiotensin III for Zona Glomerulosa Cell-Mediated Relaxations of Bovine Adrenal Cortical Arteries.
Topics: Abattoirs; Adrenal Cortex; Aldosterone; Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arterioles; Cattle; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Muscle, Smooth, Vascular; Peptide Fragments; Protease Inhibitors; Vasodilation; Zona Glomerulosa | 2018 |
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Imidazoles; Inflammation; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
Topics: ADAM17 Protein; Adaptor Proteins, Signal Transducing; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Apoptosis; beta Catenin; Cardiomegaly; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Inflammation; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinases; Mice, Inbred C57BL; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Angiotensin-(1-7) and Vascular Function: The Clinical Context.
Topics: Angiotensin I; Angiotensin II; Humans; Muscle, Smooth, Vascular; Peptide Fragments | 2018 |
Angiotensin 1-7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Animals; Cell Line; Ceruletide; Down-Regulation; Inflammation; Interleukin-10; Interleukin-6; Microscopy, Fluorescence; NF-kappa B; Peptide Fragments; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Modulating Role of Ang1-7 in Control of Blood Pressure and Renal Function in AngII-infused Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Urodynamics | 2018 |
[ACE2 agonist DIZE alleviates lung injury induced by limb ischemia-reperfusion in mice].
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Hindlimb; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Reperfusion Injury | 2018 |
FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular System; Fibroblast Growth Factors; Hypertension; Kidney; Loss of Function Mutation; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Link between FGF21 and blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Fibroblast Growth Factors; Humans; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
FGF21 ACEs hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Fibroblast Growth Factors; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Lower circulating levels of angiotensin-converting enzyme (ACE) in patients with schizophrenia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Schizophrenia | 2018 |
[Role of mesenteric lymph drainage in the balance of ACE/ACE2 in murine myocardium following hemorrhagic shock].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drainage; Fluid Therapy; Lymph; Lymph Nodes; Male; Mesentery; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Resuscitation; Shock, Hemorrhagic | 2017 |
Angiotensin (1-7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Arrestins; beta-Arrestins; Cell Line; CHO Cells; Cricetulus; Endothelial Cells; GTP-Binding Proteins; HEK293 Cells; Humans; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Lipoxin A
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line, Tumor; Disease Models, Animal; Humans; Imidazoles; Leucine; Lipopolysaccharides; Lipoxins; Male; Mice; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drugs, Chinese Herbal; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2018 |
Perindopril ameliorates lipopolysaccharide-induced brain injury through modulation of angiotensin-II/angiotensin-1-7 and related signaling pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Brain; Brain Injuries; Glutathione; Lipopolysaccharides; Male; Malondialdehyde; Peptide Fragments; Perindopril; Rats; Rats, Wistar; Signal Transduction; Transcription Factor RelA | 2018 |
Dynamics of Renin, Angiotensin II, and Angiotensin (1-7) during Pregnancy and Predisposition to Hypertension-Associated Complications.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Peptide Fragments; Pregnancy; Renin; Vasoconstrictor Agents | 2018 |
[Role of ACE2-Ang (1-7)-Mas receptor axis in heart failure with preserved ejection fraction with hypertension].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Atrial Remodeling; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Heart Failure; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition.
Topics: Adrenocortical Carcinoma; Aldosterone; Angiotensin I; Angiotensin II; Cardiovascular Diseases; Cell Line, Tumor; Culture Media, Conditioned; Cytochrome P-450 CYP11B2; Humans; Janus Kinases; Peptide Fragments; Phosphorylation; Signal Transduction; STAT Transcription Factors | 2019 |
Effects of angiotensin-(1-7) and angiotensin II on vascular tone in human cirrhotic splanchnic vessels.
Topics: Angiotensin I; Angiotensin II; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Omentum; Peptide Fragments; Renin-Angiotensin System; Vasodilation | 2018 |
Involvement of angiotensin-(1-7) in the neuroprotection of captopril against focal cerebral ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Brain Ischemia; Captopril; Male; Neuroprotection; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2018 |
Increased expression of miR-33a in monocytes from Mexican hypertensive patients in elevated carotid intima-media thickness.
Topics: Aged; Angiotensin I; Angiotensin II; Carotid Intima-Media Thickness; Case-Control Studies; Female; Humans; Hypertension; Male; MicroRNAs; Middle Aged; Monocytes; Peptide Fragments; Sterol Regulatory Element Binding Proteins | 2018 |
Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm.
Topics: Adolescent; Angiotensin I; Angiotensin II; Body Mass Index; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Pediatric Obesity; Peptide Fragments; Pregnancy; Premature Birth; Prospective Studies | 2019 |
BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system.
Topics: Angiotensin I; Angiotensin II; Animals; Cytoprotection; Down-Regulation; Heptanoic Acids; Liver; Lung Injury; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Lipoxin; Renin-Angiotensin System; Up-Regulation | 2019 |
Anti-hypersensitive effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperesthesia; Male; Mice; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Perception; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord; Vasodilator Agents | 2019 |
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Collagen Type IV; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Plant Extracts; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Renin-Angiotensin System; Resveratrol; Superoxide Dismutase | 2018 |
Anti-inflammatory effects of Ang-(1-7) via TLR4-mediated inhibition of the JNK/FoxO1 pathway in lipopolysaccharide-stimulated RAW264.7 cells.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Forkhead Box Protein O1; Interleukin-6; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 4; Mice; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
[Aliskiren inhibits angiotensin II/angiotensin 1-7(Ang II/Ang1-7) signal pathway in rats with diabetic nephropathy].
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fumarates; Male; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Unique mechanistic insights into the beneficial effects of angiotensin-(1-7) on the prevention of cardiac fibrosis: A metabolomic analysis of primary cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Cell Proliferation; Cells, Cultured; Fibroblasts; Fibrosis; Gas Chromatography-Mass Spectrometry; Glutathione; Heart Diseases; Male; Metabolome; Oxidative Stress; Peptide Fragments; Rats, Sprague-Dawley; Reactive Oxygen Species | 2019 |
Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Coronary Vessels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Nitric Oxide; Peptide Fragments; Pulmonary Artery; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2019 |
Egg White-Derived Antihypertensive Peptide IRW (Ile-Arg-Trp) Reduces Blood Pressure in Spontaneously Hypertensive Rats via the ACE2/Ang (1-7)/Mas Receptor Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Egg Proteins; Endothelium, Vascular; Male; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Vasodilation | 2019 |
Chronic Angiotensin 1-7 Infusion Prevents Angiotensin-II-Induced Cognitive Dysfunction and Skeletal Muscle Injury in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cerebrovascular Circulation; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Maze Learning; Mice; Muscle, Skeletal; Peptide Fragments; Rotarod Performance Test | 2019 |
Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Body Weight; Cardiotonic Agents; Diastole; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Kidney; Kidney Function Tests; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sitagliptin Phosphate; Up-Regulation; Ventricular Remodeling | 2019 |
Aerobic exercise training prevents obesity and insulin resistance independent of the renin angiotensin system modulation in the subcutaneous white adipose tissue.
Topics: Adipose Tissue, White; Adiposity; Angiotensin I; Angiotensin II; Animals; Biomarkers; Body Weight; Feeding Behavior; Glucose; Insulin Resistance; Male; Mice, Inbred C57BL; Obesity; Peptide Fragments; Peptides; Physical Conditioning, Animal; Renin-Angiotensin System; RNA, Messenger; Subcutaneous Fat; Thermogenesis; Uncoupling Protein 1 | 2019 |
Cardiac hypertrophy in mice submitted to a swimming protocol: influence of training volume and intensity on myocardial renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Hypertrophy, Left Ventricular; Male; Mice, Inbred BALB C; Myocardium; Peptide Fragments; Physical Conditioning, Animal; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Swimming; Ventricular Remodeling | 2019 |
Modulation of renin angiotensin system components by high glucose levels in the culture of collecting duct cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Glucose; Kidney Tubules, Collecting; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2019 |
Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracosis; Captopril; Cell Differentiation; Cell Line; Collagen; Disease Models, Animal; Female; Hedgehog Proteins; Humans; Lung; Male; Middle Aged; Myofibroblasts; Oligopeptides; Peptide Fragments; Pulmonary Fibrosis; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Silicosis | 2019 |
Protective Effect of Angiotensin (1-7) on Silicotic Fibrosis in Rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Lung; Myofibroblasts; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Silicosis | 2019 |
Prehypertension exercise training attenuates hypertension and cardiac hypertrophy accompanied by temporal changes in the levels of angiotensin II and angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Diastole; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Prehypertension; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling | 2019 |
Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Humans; Kidney; Kidney Transplantation; Male; Middle Aged; Models, Biological; Peptide Fragments; Postoperative Complications; Renin; Renin-Angiotensin System | 2019 |
Ang-(1-7) treatment attenuates lipopolysaccharide-induced early pulmonary fibrosis.
Topics: Angiotensin I; Angiotensin II; Animals; Bronchoalveolar Lavage Fluid; Cadherins; Drug Evaluation, Preclinical; Imidazoles; Lipopolysaccharides; Lung; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Random Allocation; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Transforming Growth Factor beta; Vasodilator Agents; Vimentin | 2019 |
Interaction of N-acetyl-seryl-aspartyl-lysyl-proline with the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cell Differentiation; Cells, Cultured; Collagen; Collagen Type I; Fibroblasts; Humans; Male; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Silicosis | 2019 |
Sex-related differences in the intratubular renin-angiotensin system in two-kidney, one-clip hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Constriction; Disease Models, Animal; Estrogens; Female; Hypertension; Hypertrophy, Left Ventricular; Kidney Tubules; Macrophages; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Artery; Renin-Angiotensin System; Sex Factors; Signal Transduction | 2019 |
AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Heat Stroke; Hepatocytes; Humans; Imidazoles; Inflammasomes; Inflammation; Interleukin-1beta; Liver; Liver Cirrhosis; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Prospective Studies; Pyroptosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
Therapeutic Delivery of Ang(1-7) via Genetically Modified Probiotic: A Dosing Study.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drug Administration Schedule; Lacticaseibacillus paracasei; Male; Models, Animal; Peptide Fragments; Pharmaceutical Vehicles; Probiotics; Proof of Concept Study; Rats; Rats, Inbred BN; Rats, Inbred F344; Recombinant Proteins | 2020 |
Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments | 2020 |
Assessment of Pregabalin-Induced Cardiotoxicity in Rats: Mechanistic Role of Angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Cardiotoxicity; Cyclic AMP-Dependent Protein Kinases; Heart Diseases; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinase; Pregabalin; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Stroke Volume; Ventricular Function, Left | 2020 |
Significance of the angiotensin I/angiotensin II/angiotensin-(1-7) axis in the pathogenesis of systemic sclerosis.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Female; Humans; Male; Middle Aged; Peptide Fragments; Scleroderma, Systemic; Young Adult | 2020 |
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Hypertension; Male; Nitric Oxide; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 2019 |
Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Male; Medicine, Tibetan Traditional; Peptide Fragments; Peptidyl-Dipeptidase A; Plant Preparations; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ventricular Remodeling | 2020 |
Role of Angiotensin-(1-7) via MAS receptor in human sperm motility and acrosome reaction.
Topics: Acrosome Reaction; Adult; Angiotensin I; Angiotensin II; Asthenozoospermia; Humans; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Sperm Motility; Spermatozoa | 2020 |
Severe food restriction activates the central renin angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Autoradiography; Caloric Restriction; Female; Heart Rate; Hypothalamus; Injections, Intraventricular; Losartan; Organum Vasculosum; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Preoptic Area; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Starvation; Subfornical Organ | 2020 |
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Formaldehyde; Humans; Injections, Spinal; Male; Mice; Microglia; Neurons; Nociception; p38 Mitogen-Activated Protein Kinases; Pain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord | 2020 |
High hydrostatic pressure induces atrial electrical remodeling through angiotensin upregulation mediating FAK/Src pathway activation.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Atrial Appendage; Atrial Fibrillation; Atrial Remodeling; Cell Line, Tumor; Focal Adhesion Kinase 1; Humans; Hydrostatic Pressure; Mice; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; src-Family Kinases; Up-Regulation; Valsartan | 2020 |
AVE0991, a nonpeptide angiotensin-(1-7) mimic, inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Disease Models, Animal; Humans; Imidazoles; Immunohistochemistry; Lipids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Molecular Mimicry; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments | 2020 |
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anxiety; Cerebrovascular Disorders; Down-Regulation; Electroacupuncture; Hippocampus; Male; Memory Disorders; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Up-Regulation | 2020 |
Association of circulating uric acid and angiotensin-(1-7) in relation to higher blood pressure in adolescents and the influence of preterm birth.
Topics: Adolescent; Angiotensin I; Angiotensin II; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Peptide Fragments; Pregnancy; Premature Birth; Renin; Renin-Angiotensin System; Uric Acid | 2020 |
Diminazene aceturate extenuate the renal deleterious consequences of angiotensin-II induced by γ-irradiation through boosting ACE2 signaling cascade.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Gamma Rays; Glutathione; Male; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Superoxide Dismutase | 2020 |
Critical Role of Neprilysin in Kidney Angiotensin Metabolism.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Case-Control Studies; Chymases; Enzyme Inhibitors; Female; Humans; Kidney; Male; Mice, Inbred C57BL; Middle Aged; Neprilysin; Peptide Fragments; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2020 |
Angiotensin-(1-7) receptor Mas antagonist (A779) influenced gliosis and reduced synaptic density in the spinal cord after peripheral axotomy.
Topics: Angiotensin I; Angiotensin II; Animals; Astrocytes; Axotomy; Fluorescent Antibody Technique; Gliosis; Male; Mice, Inbred C57BL; Microglia; Peptide Fragments; Receptors, G-Protein-Coupled; Spinal Cord; Synapses | 2020 |
Physiological cyclic stretch up-regulates angiotensin-converting enzyme 2 expression to reduce proliferation and migration of vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cell Movement; Cell Proliferation; Cells, Cultured; Enzyme Induction; Humans; JNK Mitogen-Activated Protein Kinases; Mechanotransduction, Cellular; Muscle Spindles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Peptide Fragments; Protein Kinase C beta; Transcription Factor AP-1 | 2020 |
Effect of angiotensin II and angiotensin-(1-7) on proliferation of stem cells from human dental apical papilla.
Topics: Adolescent; Angiotensin I; Angiotensin II; Cell Proliferation; Cells, Cultured; Dental Papilla; Female; Humans; Imidazoles; Male; MAP Kinase Signaling System; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Stem Cells | 2021 |
Apelin-potential therapy for COVID-19?
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Apelin; Apelin Receptors; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Mice; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; SARS-CoV-2 | 2020 |
SARS-CoV-2 Pathogenesis: Imbalance in the Renin-Angiotensin System Favors Lung Fibrosis.
Topics: Alveolar Epithelial Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; Host Microbial Interactions; Humans; Lung; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pulmonary Fibrosis; Receptors, Coronavirus; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Transforming Growth Factor beta | 2020 |
Angiotensin-Ⅱ and angiotensin-(1-7) imbalance affects comorbidity of depression and coronary heart disease.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Case-Control Studies; China; Comorbidity; Coronary Disease; Depression; Female; Gene Expression Regulation; Genotype; Humans; Linear Models; Male; Middle Aged; Peptide Fragments; Polymorphism, Single Nucleotide; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; ROC Curve; Signal Transduction; Surveys and Questionnaires | 2020 |
Cardioprotection Generated by Aerobic Exercise Training is Not Related to the Proliferation of Cardiomyocytes and Angiotensin-(1-7) Levels in the Hearts of Rats with Supravalvar Aortic Stenosis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Stenosis, Supravalvular; Aurora Kinase B; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclin D2; Echocardiography; Exercise Test; Male; Myeloid Ecotropic Viral Integration Site 1 Protein; Myocardium; Myocytes, Cardiac; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Wistar; Renin-Angiotensin System | 2020 |
Alteration and association between serum ACE2/ angiotensin(1-7)/Mas axis and oxidative stress in chronic kidney disease: A pilot study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Female; Humans; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Pilot Projects; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2020 |
COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Anticoagulants; Cardiovascular Diseases; COVID-19; Humans; Hypertension; Models, Theoretical; Peptide Fragments; Renin-Angiotensin System; Respiration; Risk Factors; Venous Thromboembolism; Virus Internalization | 2020 |
Angiotensin-converting enzyme 2 activator, DIZE in the basolateral amygdala attenuates the tachycardic response to acute stress by modulating glutamatergic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Basolateral Nuclear Complex; Diminazene; Glutamic Acid; Heart Rate; Neurons; Peptide Fragments; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tachycardia | 2020 |
Localization of angiotensin-(1-7) and Mas receptor in the rat ovary throughout the estrous cycle.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Enzyme Activation; Estrous Cycle; Female; Granulosa Cells; Immunohistochemistry; Ovarian Follicle; Ovary; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; RNA, Messenger | 2020 |
Altered Serum Levels of Renin-Angiotensin System Markers in Migraine.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Biomarkers; Cross-Sectional Studies; Female; Humans; Male; Migraine Disorders; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Severity of Illness Index; Young Adult | 2020 |
Different reactive species modulate the hypotensive effect triggered by angiotensins at CVLM of 2K1C hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Male; Medulla Oblongata; Peptide Fragments; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Vasoconstrictor Agents | 2020 |
Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diminazene; Imidazoles; Ischemia; Kidney; Liver; Male; Myocardium; Oxidative Stress; Peptide Fragments; Peroxidase; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2020 |
N-Acetyl-Seryl-Asparyl-Lysyl-Proline regulates lung renin angiotensin system to inhibit epithelial-mesenchymal transition in silicotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Losartan; Lung; Male; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Silicosis | 2020 |
Angiotensinergic receptors in the medial amygdaloid nucleus differently modulate behavioral responses in the elevated plus-maze and forced swimming test in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Corticomedial Nuclear Complex; Imidazoles; Losartan; Male; Maze Learning; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Swimming | 2021 |
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Female; Imidazoles; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice, Inbred BALB C; Neutrophils; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Smoke; Sulfonamides; Thiophenes; Tobacco Products | 2020 |
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2020 |
Mica Can Alleviate TNBS-Induced Colitis in Mice by Reducing Angiotensin II and IL-17A and Increasing Angiotensin-Converting Enzyme 2, Angiotensin 1-7, and IL-10.
Topics: Aluminum Silicates; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Colitis; Eating; Enzyme-Linked Immunosorbent Assay; Interleukin-10; Interleukin-17; Male; Mice; Peptide Fragments; Trinitrobenzenesulfonic Acid | 2020 |
Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose.
Topics: 3T3 Cells; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Development; Glucose; Male; Mice; Osteoblasts; Osteoclasts; Osteoporosis; Peptide Fragments; Phosphorylation; Rats; Rats, Inbred SHR; RAW 264.7 Cells | 2021 |
Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1-7) and Angiotensin II in Human Plasma.
Topics: Angiotensin I; Angiotensin II; Chromatography, Agarose; COVID-19; Enzyme-Linked Immunosorbent Assay; Humans; Peptide Fragments; Radioimmunoassay; Reference Standards; Renin-Angiotensin System; SARS-CoV-2; Sensitivity and Specificity; Specimen Handling | 2021 |
Metabolism of angiotensin peptides by angiotensin converting enzyme 2 (ACE2) and analysis of the effect of excess zinc on ACE2 enzymatic activity.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Humans; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins; Renin-Angiotensin System; Zinc | 2021 |
ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Vascular Endothelial Growth Factor A | 2021 |
Renin-angiotensin-aldosterone system peptide profiles in patients with COVID-19.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Case-Control Studies; COVID-19; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Prospective Studies; Renin; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex.
Topics: Adrenal Cortex; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Peptide Fragments; Proto-Oncogene Mas | 2021 |
Strengthening CoViD-19 therapy via combinations of RAS modulators.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19 Drug Treatment; Humans; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2021 |
Myocardial Angiotensin Metabolism in End-Stage Heart Failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Disease Progression; Female; Heart Failure; Heart Transplantation; Humans; Male; Mass Spectrometry; Middle Aged; Myocardium; Peptide Fragments; Renin-Angiotensin System; Stroke Volume | 2021 |
Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Female; Gene Expression Profiling; HLA-DR Antigens; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Peptide Fragments; Pilot Projects; Prospective Studies; RNA, Messenger; Virus Shedding | 2021 |
Scorpion bradykinin potentiating factor mitigates lung damage induced by γ-irradiation in rats: Insights on AngII/ACE/Ang(1-7) axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Gamma Rays; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Scorpions | 2021 |
Sex differences in the lung ACE/ACE2 balance in hypertensive rats.
Topics: ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Down-Regulation; Female; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Sex Characteristics | 2021 |
Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries.
Topics: ADAM17 Protein; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Enzyme Activation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peptide Fragments; Prognosis; Prospective Studies; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Renin-Angiotensin System; Respiration, Artificial; Risk; SARS-CoV-2; Treatment Outcome | 2022 |
Angiotensin (ang) 1-7 inhibits ang II-induced atrial fibrosis through regulating the interaction of proto-oncogene tyrosine-protein kinase Src (c-Src) and Src homology region 2 domain-containing phosphatase-1 (SHP-1)).
Topics: Angiotensin I; Angiotensin II; Animals; Fibrosis; Matrix Metalloproteinase 2; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; Signal Transduction; src Homology Domains; Transforming Growth Factor beta | 2021 |
The Effects of Angiotensin II or Angiotensin 1-7 on Rat Pial Microcirculation during Hypoperfusion and Reperfusion Injury: Role of Redox Stress.
Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Female; Male; Microcirculation; Microscopy, Fluorescence; Peptide Fragments; Pia Mater; Proto-Oncogene Mas; Rats; Reactive Oxygen Species; Reperfusion Injury; Tetrazoles | 2021 |
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase | 2021 |
Renin-angiotensin system blockade on angiotensin-converting enzyme 2 and TMPRSS2 in human type II pneumocytes.
Topics: Adult; Age Factors; Aged; Alveolar Epithelial Cells; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Lung; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Retrospective Studies; Serine Endopeptidases; Smoking | 2022 |
Angiotensin-(1-7), a protective peptide against vascular aging.
Topics: Aged; Aging; Angiotensin I; Angiotensin II; Frailty; Humans; Peptide Fragments; Renin-Angiotensin System | 2022 |
Exercise training improves cardiovascular control in sinoaortic denervated SHR by reducing the elevated angiotensin II and augmenting angiotensin-(1-7) availability within autonomic and neuroendocrine PVN nuclei.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Hypertension; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred SHR | 2022 |
Angiotensin-(1-7) promotes mitochondrial translocation of human telomerase reverse transcriptase in HUVECs through the TOM20 complex.
Topics: Angiotensin I; Angiotensin II; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Peptide Fragments; Telomerase | 2022 |
Angiotensin 1-7 mitigates rhabdomyolysis induced renal injury in rats via modulation of TLR-4/NF-kB/iNOS and Nrf-2/heme‑oxygenase-1 signaling pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Heme; Kidney; Male; NF-kappa B; Nitric Oxide Synthase Type II; Peptide Fragments; Rats; Receptors, G-Protein-Coupled; Rhabdomyolysis; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Renin-Angiotensin System in Huntington's Disease: Evidence from Animal Models and Human Patients.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Humans; Huntington Disease; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2022 |
Angiotensin (1-7) Delivered Orally via Probiotic in Combination With Exercise: Sex-Dependent Influence on Health Span.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Peptide Fragments; Quality of Life; Rats; Renin-Angiotensin System | 2023 |
Activation of Angiotensin-converting Enzyme 2 Protects Against Lipopolysaccharide-induced Glial Activation by Modulating Angiotensin-converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents; Lipopolysaccharides; Male; Neuroglia; Neuroinflammatory Diseases; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2023 |
Effects of intrarenal angiotensin 1-7 infusion on renal haemodynamic and excretory function in anaesthetised two-kidney one-clip and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Acetates; Angiotensin II; Animals; Desoxycorticosterone Acetate; Hemodynamics; Hypertension; Kidney; Rats | 2023 |
Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype | 2022 |
Angiotensin-(1-7) ameliorates sepsis-induced cardiomyopathy by alleviating inflammatory response and mitochondrial damage through the NF-κB and MAPK pathways.
Topics: Angiotensin II; Cardiomyopathies; Cells, Cultured; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Sepsis | 2023 |
Anti-Fibrotic Potential of Angiotensin (1-7) in Hemodynamically Overloaded Rat Heart.
Topics: Angiotensin II; Animals; Connexin 43; Fibrosis; Heart; Heart Failure; Hypertension; Male; Rats; Rats, Transgenic | 2023 |
Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor-Biased Ligand in Adults With COVID-19: Two Randomized Clinical Trials.
Topics: Adult; Angiotensin II; Angiotensins; COVID-19; Female; Humans; Hypoxia; Infusions, Intravenous; Ligands; Male; Middle Aged; Oligopeptides; Randomized Controlled Trials as Topic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; SARS-CoV-2; Vasodilator Agents | 2023 |
All-trans retinoic acid inhibits oxidative stress via ACE2/Ang (1-7)/MasR pathway in renal tubular epithelial cells stimulated with high glucose.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Epithelial Cells; Fibrosis; Glucose; Humans; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Tretinoin | 2023 |
Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7).
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Claudin-1; Dysbiosis; Gastrointestinal Microbiome; Male; Mice; Occludin; Peptide Fragments; Peptidyl-Dipeptidase A | 2023 |
Ang-(1-7) attenuates podocyte injury induced by high glucose
Topics: Angiotensin II; Animals; Diabetic Nephropathies; Glucose; Mice; Podocytes | 2023 |
Effects of Angiotensin 1-7 and Mas Receptor Agonist on Renal System in a Rat Model of Heart Failure.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Heart Failure; Kidney; Peptide Fragments; Rats; Renin-Angiotensin System | 2023 |
Altered renin-angiotensin system gene expression in airways of antigen-challenged mice: ACE2 downregulation and unexpected increase in angiotensin 1-7.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Asthma; COVID-19; Down-Regulation; Gene Expression; Mice; Ovalbumin; Renin-Angiotensin System; SARS-CoV-2 | 2023 |
Inhibition of smooth muscle cell death by Angiotensin 1-7 protects against abdominal aortic aneurysm.
Topics: Angiotensin II; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Apoptosis Regulatory Proteins; Disease Models, Animal; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Reactive Oxygen Species | 2023 |