angiotensin ii has been researched along with angiotensin i in 2141 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 467 (21.81) | 18.7374 |
| 1990's | 638 (29.80) | 18.2507 |
| 2000's | 467 (21.81) | 29.6817 |
| 2010's | 450 (21.02) | 24.3611 |
| 2020's | 119 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Coffman, TM; Cunha, TS; Elased, KM; Gurley, SB; Morris, M | 1 |
| Averill, DB; Chappell, MC; Diz, DI; Ferrario, CM; Figueroa, JP; Rose, JC; Shaltout, HA; Westwood, BM | 1 |
| Castro, P; Collantes, P; Copaja, M; Diaz-Araya, G; Godoy, I; Jalil, JE; Lavandero, S; Ocaranza, MP; Pinto, M; Ramirez, C; Roman, M; Varas, M | 1 |
| Arthur, JM; Bland, AM; Janech, MG; Raymond, JR; Velez, JC | 1 |
| Oliveira, EB; Pereira, HJ; Salgado, MC; Souza, LL | 1 |
| Apablaza, F; Chiong, M; Godoy, I; Gonzalez, L; Hernandez, C; Jalil, JE; Lavandero, S; Lopez, R; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M; Varas, M; Verdejo, H | 1 |
| Buczko, W; Kramkowski, K; Leszczynska, A; Mogielnicki, A | 1 |
| Costa-Neto, CM; Oliveira, EB; Pereira, HJ; Salgado, MC; Souza, LL | 1 |
| Batlle, D; Evora, K; Garcia-Halpin, L; Gonzalez-Pacheco, FR; Poglitsch, M; Salem, M; Schuster, M; Wysocki, J; Ye, M | 1 |
| Bujak-Gizycka, B; Gebska, A; Jawien, J; Korbut, R; Kus, K; Madej, J; Olszanecki, R; Suski, M; Toton-Zuranska, J | 1 |
| Cha, SA; Gao, S; Kim, SH; Park, BM | 1 |
| Alzamora, R; Ayala, P; Barrientos, V; Chiong, M; Díaz-Araya, G; Escudero, N; García, L; Godoy, I; Hevia, D; Jalil, JE; Lavandero, S; Michea, L; Morales, C; Moya, J; Novoa, U; Ocaranza, MP; Pinto, M | 1 |
| Akashi, AP; Amaral, SL; Becari, C; Colombini-Ishikiriama, BL; Didier, DN; Dionísio, TJ; Faria, FA; Figueiredo, CM; Garlet, GP; Greene, AS; Lima, MC; Maciel, RP; Matus, I; Morandini, AC; Oliveira, EB; Rodini, CO; Salgado, MC; Santos, CF; Sipert, CR; Souza, GP | 1 |
| Azocar, A; Castro, PF; Chiong, M; Jalil, JE; Lavandero, S; Mendoza-Torres, E; Mondaca-Ruff, D; Ocaranza, MP; Oyarzún, A | 1 |
| Kittana, N | 1 |
| Awan, FR; Hussain, M | 1 |
| Barrett, JD; Eggena, P; Sambhi, MP | 1 |
| Bangham, DR; Robertson, I; Robertson, JI; Robinson, CJ; Tree, M | 1 |
| Ganten, D; Stock, G | 1 |
| Ackerly, JA; Gianfagna, W; Miller, ED; Peach, MJ | 1 |
| Hermle, M; Schnermann, J; Stowe, N | 1 |
| Ercan, ZS; Türker, RK | 1 |
| Amery, AK; Lijnen, PJ | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP; Millar, JA | 2 |
| Atkinson, AB; Brown, JJ; Davies, DL; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Aikawa, T; Hashiba, K; Ishikawa, E; Kitagawa, T; Murayama, M; Suzuki, S | 1 |
| Anees, M; Mulrow, PJ; Sweet, P; Tan, SY | 1 |
| Hansmann, M; Kaulhausen, H; Oney, T; Venbrocks, RA | 1 |
| Boccagno, JA; Vollmer, RR | 1 |
| Heinemann, HO; Ryan, JW; Ryan, US | 1 |
| Goldberg, ME; Murthy, VS; Vollmer, RR; Waldron, TL | 1 |
| Devynck, MA; Meyer, P | 1 |
| Coviello, A; Elso, G; Orce, G; Raisman, R | 1 |
| Antonaccio, MJ; Goldberg, ME; Goldenberg, HJ; Harris, DN; Heran, CL; High, JP; Laffan, RJ; Rubin, B | 1 |
| Bor, N; Ercan, ZS; Oner, G; Türker, RK | 1 |
| Cornish, KG; Gilmore, JP; Joyner, WL | 3 |
| Davis, JO; DeForrest, JM; Freeman, RH; Stephens, GA; Watkins, BE | 1 |
| Magnan, J; Regoli, D | 1 |
| Felix, D; Ganten, D; Hoffman, WE; Phillips, MI; Weyhenmeyer, J | 1 |
| Jung, D | 1 |
| Casals-Stenzel, J; Lever, AF; Millar, JA; Morton, JJ; Riegger, AJ; Tree, M | 1 |
| Barney, CC; Fregly, MJ; Katovich, MJ; McCaa, RE | 1 |
| Baumann, R; Kuhl, H | 1 |
| Swales, JD | 1 |
| Amery, AK; Fagard, RH; Lijnen, PJ | 1 |
| Johnston, CI; Matthews, PG; McGrath, BP | 2 |
| Peach, MJ | 1 |
| Brown, JJ; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Padfield, PL; Robertson, JI; Semple, PF | 1 |
| Dietz, R; Ganten, D; Mann, JF; Rascher, W; Schömig, A | 1 |
| Abe, Y; Kishimoto, T; Okahara, T; Yamamoto, K | 1 |
| Atkinson, AB; Brown, JJ; Fraser, R; Leckie, B; Lever, AF; Morton, JJ; Robertson, JI | 1 |
| Ganten, D; Schölkens, B; Steinbach, R | 1 |
| Chiu, AT; Day, AR; Freer, RJ; Sutherland, JC | 1 |
| Bakhle, YS; Hartiala, J; Toivonen, H; Uotila, P | 1 |
| Beierwaltes, WH; Britton, SL; Fiksen-Olsen, MJ; Romero, JC | 1 |
| Iso, T; Iwao, J; Nishimura, K; Oya, M | 1 |
| Chrabaszcz, G; Oparil, S; Peterson, DR; Peterson, WR | 1 |
| Alekseenko, LP; Orekhovich, VN; Pozdnev, VF; Zolotov, NN | 1 |
| Malvin, RL | 1 |
| Reid, IA | 2 |
| Navar, LG; Ploth, DW | 1 |
| Beierwaltes, WH; Britton, SL; Fiksen-Olsen, MJ; Romero, JC; Sexton, JM | 1 |
| Mendelsohn, FA | 1 |
| Stein, JH | 1 |
| Cier, JF | 1 |
| Lefer, AM; Trachte, GJ | 1 |
| Cumming, AM; Millar, JA; Semple, PF | 1 |
| Ferriss, JB; Gonggrijp, H; Long, AA; O'Sullivan, DJ; Sullivan, PA | 1 |
| Eguchi, T; Kondo, K; Nakamura, R; Okuno, T; Saruta, T; Yasui, T | 1 |
| Bökesoy, TA; Ercan, ZS; Türker, RK | 1 |
| Munday, KA; Noble, AR; Rowe, BP | 4 |
| Bakhle, YS; Ben-Harari, RR | 1 |
| Holcombe, RF; Opdyke, DF | 1 |
| Brunner, HR; Ferguson, RK; Gavras, H; Jaeger, P; Kirchertz, EJ | 1 |
| Prószyńska, K | 1 |
| Kotchen, TA; Talwalkar, RT; Welch, WJ | 1 |
| Bumpus, FM; Nishimura, H; Norton, VM | 1 |
| Staszewska-Barczak, J | 1 |
| Adam, T; Macgregor, GA; Markandu, ND; Roulston, JE | 1 |
| Hayashi, S; Miyazaki, M; Toda, N | 1 |
| Fahrer, A; Ganten, D; Rettig, R; Schelling, P; Simon, W; Speck, G | 1 |
| Bönner, G; Ganten, D; Gless, KH; Gram, N; Helber, A; Mann, JF | 1 |
| Gaynes, RP; Oparil, S; Szidon, JP | 1 |
| Baranowski, RL; Kurtzman, NA; Westenfelder, C | 1 |
| Csicsmann, J; Hutchinson, JS | 1 |
| Mackenzie, JC; Osborn, EC; Rigby, GV; Sugden, PL; Wilton, A | 1 |
| Hirose, T; Matsuzaki, Y; Nagano, H; Sugiyama, K | 1 |
| Jin, XR; Wang, DX; Yu, XL | 1 |
| Brunner, HR; Christen, Y; Lee, RJ; Munafo, A; Nussberger, J; Waeber, B | 1 |
| Guo, J | 1 |
| Davenport, A; Goodship, AE; Mackenzie, JC; Osborn, EC | 1 |
| Brosnihan, KB; DiCorleto, PE; Ferrario, CM; Jacobsen, DW; Santos, RA | 1 |
| Fox, J; Guan, S; Hymel, AA; Navar, LG | 1 |
| Dzau, VJ; Wilcox, CS | 1 |
| Leite, R; Salgado, MC | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Yamamoto, K | 1 |
| Li, T; Zimmerman, BG | 2 |
| Brunner, D; Brunner, HR; Keller, I; Nussberger, J | 1 |
| Hiramori, K; Imanashi, M; Ito, K; Kawamura, M; Matsushima, Y | 1 |
| Bost, JG; Leenders, PJ; Nelissen-Vrancken, MH; Smits, JF; Struijker-Boudier, HA | 1 |
| Chiyotani, A; Isono, K; Kanemura, T; Konno, K; Sakai, N; Tamaoki, J | 1 |
| Fedorov, VI | 1 |
| Fox, J; Guan, S; Mitchell, KD; Navar, LG | 1 |
| Konno, K; Tamaoki, J; Yamauchi, F | 1 |
| Paul, M; Schunkert, H | 1 |
| Beraldo, WT; Gualberto, MP; Nunes, RL; Pesquero, JL | 1 |
| Atkins, JF; Dayhuff, TJ; Gesteland, RF | 1 |
| Okamura, T; Toda, N; Wang, Y | 1 |
| Krieger, EM; Lovenberg, WM; Yamori, Y | 1 |
| Baracho, NC; Santos, RA | 1 |
| Diz, DI; Pirro, NT | 1 |
| Armstrong, PW; Forster, C; Larosa, G | 1 |
| Baker, KM; Conrad, KM; Cooper, GR; Dostal, DE; Rothblum, KN | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA | 1 |
| Armanini, D; Caregaro, L; D'Agostino, D; Fallo, F; Mantero, F | 1 |
| Braszko, J; Hoły, Z; Kupryszewski, G; Wiśniewski, K; Witczuk, B | 1 |
| Fukuchi, S; Gomibuchi, T; Haga, H; Mizuno, K; Niimura, S; Sanada, H; Tani, M | 1 |
| Carey, RM; Geary, KM; Gomez, RA; Hunt, MK; Norling, LL; Peach, MJ; Ramos, SP | 1 |
| Head, GA; Williams, NS | 1 |
| Hermann, K; Ring, J; Rittweger, R | 2 |
| Bie, P; Emmeluth, C | 1 |
| Chiu, AT; McCall, DE; Roscoe, WA | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; Widdop, RE | 1 |
| Balfagón, G; Encabo, A; Ferrer, M; Marín, J | 2 |
| Davies, E; Edwards, CR; Flapan, AD; Rademaker, M; Shaw, TR; Williams, BC | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Koning, MM; Schalekamp, MA; Verdouw, PD | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Koning, MM; Sassen, LM; Schalekamp, MA; Verdouw, PD | 1 |
| Andersson, KE; Hedlund, H; Stahl, M | 1 |
| Hermann, K; Phillips, MI; Ring, J; Rittweger, R | 1 |
| Bottari, SP; Steckelings, UM; Unger, T | 1 |
| Grinstead, WC; Young, JB | 1 |
| Caputo, FA; Fregly, MJ; Rowland, NE | 1 |
| Dunne, JF; Melching, G; Momiyama, M; Ransom, JT; Sharif, NA | 1 |
| de Jong, JW; Huizer, T; van der Meer, P | 1 |
| Allen, AM; Mendelsohn, FA; Paxinos, G; Song, K | 1 |
| Dessì-Fulgheri, P; Fallo, F; Lanari, A; Mantero, F; Paci, VM; Pistorello, M; Rappelli, A; Sarzani, R | 1 |
| Fukuchi, S; Haga, H; Hashimoto, S; Mizuno, K; Niimura, S; Ohtsuki, M; Sanada, H; Tani, M; Watanabe, H | 1 |
| Campbell, DJ; Clark, IJ; Lawrence, AC | 1 |
| Claybaugh, JR; Hashiro, GM; Hebden, RA | 1 |
| Silldorff, EP; Stephens, GA | 1 |
| Jarrott, B; Krstew, E; Widdop, RE | 1 |
| Batista, EN; Campagnole-Santos, MJ; Heringer, SB; Khosla, MC; Santos, RA | 1 |
| Bünning, P; Gohlke, P; Unger, T | 1 |
| Fujitsuka, T; Ishida, R; Kubo, M | 1 |
| Epstein, WL; Fukuyama, K; Hara, K; Iida, T; Nozaki, Y; Sato, N | 1 |
| De Mey, JG; Schiffers, PM; Struyker-Boudier, HA | 1 |
| Araujo, GW; Lindsey, CJ; Paiva, AC; Pesquero, JB; Pesquero, JL | 1 |
| Saavedra, JM; Strömberg, C; Tsutsumi, K; Viswanathan, M | 1 |
| Chai, SY; Jackson, B; Johnston, CI; Kohzuki, M; Mendelsohn, FA; Paxton, D; Perich, R | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Greene, LJ; Santos, RA; Welches, WR | 1 |
| Uchendu, CN; Wong, PY | 2 |
| Byrd, EW; Carr, BR; Rainey, WE; Sinnokrot, RA | 1 |
| Li, TC; Zimmerman, BG | 1 |
| Fortier, P; Godin, D; Lambert, C; Nadeau, R | 1 |
| Bidiville, J; Brunner, HR; Burnier, M; Juillerat, L; Mooser, V; Nussberger, J; Pauly, N; Waeber, B | 1 |
| Arakawa, K; Ideishi, M; Ikeda, M; Sasaguri, M | 2 |
| Ayajiki, K; Okamura, T; Okunishi, H; Toda, N | 1 |
| Levens, NR | 4 |
| Gasic, S; Heinz, G; Kleinbloesem, CH; Waldhäusl, W | 1 |
| Miledi, R; Woodward, RM | 1 |
| Abou-Samra, AB; Bergwitz, C; Jüppner, H; Madoff, S | 1 |
| Brunner, HR; Camenzind, E; Coassolo, P; Fischli, W; Juillerat, L; Kleinbloesem, CH; Munafo, A; Nussberger, J; van Brummelen, P; Waeber, B | 1 |
| Jackson, EK | 1 |
| Chappell, MC; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC | 1 |
| Higaki, J; Miyazaki, M; Morishita, R; Ogihara, T | 1 |
| Boulanger, CM; Bühler, FR; Dohi, Y; Hahn, AW; Lüscher, TF | 1 |
| Jackson, EK; Pong, AS; Tofovic, SP | 1 |
| Aso, T; Kubota, T | 1 |
| Sato, Y | 1 |
| Fearn, LM; Francis, RJ; MacKenzie, JC; Osborn, EC; Wilson, J | 1 |
| Ertl, G; Haas, U; Neubauer, S; Pulzer, F; Tian, R | 1 |
| Templ, E; Templ, H | 1 |
| Brunner, HR; Evéquoz, D; Flückiger, JP; Hui, KY; Nussberger, J; Waeber, B | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Sassen, LM; Schalekamp, MA; Verdouw, PD | 1 |
| Branca, Q; Clozel, JP; el Amrani, K; Fischli, W; Neidhart, W; Stadler, H; Wostl, W | 1 |
| Fearn, LM; Mackenzie, JC; Osborn, EC | 1 |
| Franco-Saenz, R; Lotshaw, DP; Mulrow, PJ; Oda, H | 1 |
| Brosnihan, KB; Chappell, MC; Ferrario, CM; Khosla, MC; Kohara, K | 1 |
| Kawaguchi, H; Sawa, H; Yasuda, H | 5 |
| Story, DF; Ziogas, J | 3 |
| Campbell, DJ; Kladis, A; Skinner, SL; Whitworth, JA | 1 |
| Chiou, CY; Fallo, F; Kifor, I; Menachery, A; Moore, TJ; Sperling, E; Williams, GH | 1 |
| Lundin-Schiller, S; Mitchell, MD | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Tallant, EA | 1 |
| Admiraal, PJ; Derkx, FH; Fischli, W; Man in't Veld, AJ; Schalekamp, MA; van Brummelen, P; van den Meiracker, AH | 1 |
| Beutler, JJ; Boer, P; Dorhout Mees, EJ; Koomans, HA; Rabelink, AJ; Vos, PF | 1 |
| Bihovsky, R; Chou, YL; Erhardt, PW; Lumma, WC; Mohan, R; Shaw, KJ | 1 |
| Andersson, B; Eriksson, S | 1 |
| Higashimori, K; Inagami, T; Mizuno, K | 3 |
| Bernadet, P; Chatellier, G; Guyene, TT; Kleinbloesem, CH; Ménard, J | 1 |
| Baum, HP; Bunkenburg, B; Cumin, F; Schnell, C; Wood, JM | 1 |
| Aalkjaer, C; Kvist, S; Mulvany, MJ | 1 |
| Correa, FM; Saavedra, JM; Tsutsumi, K; Viswanathan, M | 1 |
| Fregly, MJ; Rowland, NE | 5 |
| Kerkhoff, J; van den Buuse, M | 1 |
| Bumpus, FM | 1 |
| Brosnihan, KB; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Milsted, A; Tallant, EA | 1 |
| Faraci, FM; Heistad, DD; Maktabi, MA | 1 |
| Mayer, E; Richardt, G; Schömig, A | 1 |
| Akabane, S; Imanishi, M; Ito, K; Kawamura, M; Kuramochi, M; Matsushima, Y; Omae, T | 1 |
| Szurkowski, M; Wiecek, A | 1 |
| Coviello, A; de Bruno, MP | 1 |
| Ganten, D; Hilgenfeldt, U; Hilgers, KF; Mann, JF | 1 |
| Borland, RM; Brunner, HR; Christen, Y; Lee, RJ; Maggon, K; Nussberger, J; Porchet, M; Shum, L; Timmermans, PB; Waeber, B | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Tallant, EA | 1 |
| Samani, NJ | 1 |
| Barnes, KL; Felix, D; Ferrario, CM; Imboden, H; Khosla, MC; Montani, B | 1 |
| Cononie, CC; Graves, JE; Hagberg, JM; Phillips, MI; Pollock, ML; Sumners, C | 1 |
| Catt, KJ; Ji, H; Millan, MA; Sandberg, K | 1 |
| Hosoi, M; Kim, S; Shimamoto, K; Takada, T; Yamamoto, K | 1 |
| Matsuo, H; Nishida, M; Obata, H; Sano, H; Yasuda, H | 1 |
| Fukuda, Y; Inukai, T; Kuroda, K; Nakao, K | 1 |
| Bigorgne, JC; Corvol, P; Denolle, T; Galland, F; Guyene, TT; Rohmer, V; Saint-Adnré, JP; Schambelan, M | 1 |
| Andries, LJ; Brutsaert, DL; Meulemans, AL | 1 |
| Anderson, JW; Jennings, DB; Sarda, IR | 1 |
| Gecse, A; Mezei, Z; Telegdy, G; Zádori, J | 1 |
| Bennett, T; Gardiner, SM; Tomlinson, KC | 1 |
| Gasic, S; Heinz, G; Kleinbloesem, C | 1 |
| Sheng, DY; Wang, YM | 1 |
| Biollaz, J; Brunner, HR; Leuenberger, P; Nussberger, J; Vonmoos, S; Waeber, B | 1 |
| Dzau, VJ; Stevenson, L; Tang, SS | 1 |
| Bumpus, FM; Healy, B; Husain, A; Stewart, RW; Urata, H | 1 |
| Bodzin, JH; Ehrinpreis, MN; Jaszewski, R; Korlipara, R; Peleman, RR; Tolia, V; Weinstock, JV | 1 |
| Bumpus, FM; Daud, AI; Husain, A | 1 |
| Campbell, DJ; Kladis, A | 1 |
| Iizuka, K; Kawaguchi, H; Sawa, H; Yasuda, H | 1 |
| Ganten, D; Hellmann, T; Keuneke, C; Metzger, R; Peters, J; Yacullo, R | 1 |
| Rónai, AZ | 1 |
| Fu, WO; Huang, SJ; Law, WK; Wong, PY | 1 |
| Cohen, ML; Neubauer, BL; Steidle, CP | 1 |
| Raimbach, SJ; Thomas, AL | 1 |
| Epstein, WL; Fukuyama, K; Hirayama, K | 1 |
| Majewski, H; Murphy, TV | 1 |
| Brunner, HR; Christen, Y; Graf, P; Juillerat, L; Ménard, J; Mooser, V; Nussberger, J; Waeber, B | 1 |
| Apstein, CS; Dzau, VJ; Hirsch, AT; Lorell, BH; Schunkert, H; Tang, SS | 1 |
| Erdös, EG; Skidgel, RA | 1 |
| Inagami, T; Kawamura, M; Mizuno, K; Naruse, K; Okamura, T | 1 |
| Bumpus, FM; Fouad-Tarazi, FM; Healy, B; Hirakata, H; Husain, A; Khosla, M; Kumagai, H; Urata, H | 1 |
| Ganten, D; Mullins, JJ; Peters, J | 1 |
| Braso, MA; Gubert, S; Ortiz, JA; Sacristán, A | 1 |
| Campbell, DJ; Kladis, A; Ziogas, J | 1 |
| Hasegawa, Y; Takei, Y | 1 |
| Center, DM; Danilov, SM; Farber, HW; Rounds, S | 1 |
| Judd, AM; Kubota, T; MacLeod, RM | 1 |
| Cressier, F; Eglème, C; Wood, JM | 1 |
| Jacobsen, J; Poulsen, K | 2 |
| Han, JS; Wang, KW | 1 |
| Ganten, D; Jin, MW; Lindpaintner, K; Niedermaier, N; Wilhelm, MJ | 1 |
| Wen, S | 1 |
| Fujioka, H; Hada, T; Higashino, K; Iwahashi, N; Maeda, J; Nakano, T; Tamura, S; Yamamoto, T | 1 |
| Admiraal, PJ; Danser, AH; Derkx, FH; Pieterman, H; Schalekamp, MA | 2 |
| Hermann, K; Ring, J | 4 |
| Fukuchi, S; Higashimori, K; Inagami, T; Mizuno, K; Shimamoto, K; Stone, WJ | 1 |
| Bumpus, FM; Husain, A; Kinoshita, A; Misono, KS; Urata, H | 1 |
| Andre, P; Nehlig, H; Schott, C; Stoclet, JC | 1 |
| Rump, LC; Schollmeyer, P; Schuster, MJ; Wilde, K | 1 |
| Müller-Schweinitzer, E; Olea-Baza, I | 1 |
| Ferrario, C; Fouad-Tarazi, FM; Khosla, M; Kumagai, H | 1 |
| Campagnole-Santos, MJ; Diz, DI; Ferrario, CM | 1 |
| Lin, C; Stone, RA; Wax, MB | 1 |
| Barnes, KL; Ferrario, CM; Knowles, WD | 1 |
| Ferrario, CM; Khosla, MC; Meixner, K; Trachte, GJ | 1 |
| Holm, A; Lauritzen, E; Masson, M; Rubin, I | 1 |
| Fregly, MJ; Paulding, W; Rowland, NE | 1 |
| Barnes, KL; Block, CH; Brosnihan, KB; Diz, DI; Ferrario, CM; Khosla, MC; Santos, RA | 1 |
| Drummer, OH; Johnson, H; Kourtis, S | 2 |
| Atrash, B; Donovan, B; Hallett, A; Jones, DM; Leckie, B; Lever, AF; Morton, JJ; Sueiras-Diaz, J; Szelke, M; Tree, M | 1 |
| Brunner, HR; Nussberger, J; Waeber, B | 2 |
| Baudouin, B; Geniteau Legendre, M; Moullier, P; Picard, C; Ronco, P; Verroust, P; Yao, J | 1 |
| Biollaz, J; Brunner, HR; Nussberger, J; Waeber, B | 1 |
| Brunner, HR; Bussien, JP; Fasanella d'Amore, T; Francis, RJ; Kler, L; Nussberger, J; Turini, GA; Waeber, B | 1 |
| Brown, AN; Brunner, DB; Brunner, HR; Fasanella d'Amore, T; Francis, RJ; Kler, L; Nussberger, J; Porchet, M; Waeber, B | 1 |
| Li, T; Rassier, ME; Zimmerman, BG | 1 |
| Collier, JG; Webb, DJ | 2 |
| Miyazaki, M; Okamura, T; Okunishi, H; Toda, N | 2 |
| Aalkjaer, C; Juul, B; Mulvany, MJ | 1 |
| Arakawa, K; Ikeda, M; Maruta, H; Sasaguri, M | 1 |
| Hayashi, K; Ito, K; Murakami, T; Nakashima, T | 1 |
| Chai, SY; Jackson, B; Johnson, CI; Mendelsohn, FA; Sakaguchi, K | 1 |
| Boer, P; Boer, WH; Dorhout Mees, EJ; Koomans, HA | 1 |
| Canonico, PL | 1 |
| Ehmke, H; Kirchheim, H; Kögler, U; Persson, PB | 1 |
| Berridge, MJ; Burgoyne, RD; Cheek, TR; Colyer, J; East, JM; Lee, AG; Mata, AM; Moreton, RB; Morgan, A; O'Sullivan, AJ | 1 |
| Giese, J; Hommel, E; Mathiesen, ER; Nielsen, MD; Parving, HH; Schütten, HJ | 1 |
| Albus, U; Just, M; Kaiser, J; Linz, W; Petry, P; Qi, BY; Schölkens, BA | 1 |
| Hermann, K; Phillips, MI; Raizada, MK | 1 |
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| Hackenthal, E; Hilgenfeldt, U; Rix, E; Taugner, R | 1 |
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| Bazan, SGZ; Casarini, DE; Cicogna, AC; da Silva, VL; de Campos, DHS; de Oliveira, EM; de Souza, SLB; Fernandes, T; Gatto, M; Gomes, ERM; Mota, GAF; Padovani, CR; Sant'Ana, PG; Sugizaki, MM; Vileigas, DF | 1 |
| Cao, JJ; Zheng, H | 1 |
| Lu, K; Shi, C; Xia, H; Zhang, B; Zhang, P | 1 |
| Casarini, DE; Messias, A; Paula, JS; Seki, VBB; Souza, GR | 1 |
| Gan, R; Georgius, P; Henshaw, DJE; Noble, EP; Rosoman, NP; Sommerfeld, N | 1 |
| Jha, S; Macheroux, P; Speth, RC | 1 |
| Correa, AMB; de Almeida, JFQ; Ferreira, AJ; Fontes, MAP; Kushmerick, C; Moreira, FA; Patel, KP; Sharma, NM; Silva, CC | 1 |
| Filipeanu, CM; Guidry, JJ; Lazartigues, E; Mukerjee, S; Ogunlade, B; Sriramula, S | 1 |
| Casalechi, M; Cassali, GD; Pereira, VM; Reis, AM; Reis, FM; Santos, RAS; Santos, SHS | 1 |
| Bhering Martins, L; Braga Tibaes, JR; Ferreira, AVM; Gomez, RS; Rodrigues, AMDS; Silva de Miranda, A; Teixeira, AL | 1 |
| Bragina, ME; Costa-Fraga, F; Ebadi, B; Fraga-Silva, RA; Ruoccolo, RT; Santos, RAS; Stergiopulos, N; Sturny, M | 1 |
| Alzamora, AC; Barbosa, CM; Barbosa, MA; Campagnole-Santos, MJ; de Sousa, GG; Lima, TC; Souza Dos Santos, RA | 1 |
| Gaikwad, AB; Sharma, N | 1 |
| Gao, X; Ge, X; Jin, F; Li, S; Li, Y; Mao, N; Wei, Z; Xu, H; Yang, F; Yang, Y; Zhang, M; Zhang, Y | 1 |
| Costa-Ferreira, W; Crestani, CC; Marchi-Coelho, C; Moreno-Santos, B | 1 |
| Heng, CKM; Liao, W; Mei, D; Tan, WSD; Wong, WSF | 1 |
| Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL | 1 |
| Bai, B; Gao, Z; Li, J; Peng, L; Wang, Y; Wei, X; Zhu, W | 1 |
| Lv, B; Meng, L; Shen, M; Wang, M; Zhang, B | 1 |
| Li, WX; Li, Y; Lin, FH; Lin, WP; Poon, CC; Sha, NN; Shi, W; Wang, YF; Wang, YJ; Zhang, JL; Zhang, Y | 1 |
| Akula, S; Berglund, P; Fu, Z; Hellman, L; Thorpe, M | 1 |
| Rakugi, H; Takeshita, H; Yamamoto, K | 1 |
| De, A; Pande, V; Sinha, A; Tiwari, A | 2 |
| Cohen, JB; Edmonston, DL; South, AM; Sparks, MA | 1 |
| Ahmad, S; Cheng, CP; Ferrario, CM; Groban, L; Sun, X; VonCannon, JL; Wang, H; Wright, KN | 1 |
| Balestrieri, A; Barcellona, D; Caocci, G; Castagnola, M; Cau, R; Coghe, F; Coni, P; D'Andrea, F; Faa, G; Fanni, D; Gerosa, C; La Nasa, G; Ledda, F; Marongiu, F; Orru, G; Piras, M; Ronchi, A; Saba, L; Suri, JS | 1 |
| Chen, A; Desai, AA; Han, Y; Pan, Y; Tang, H; Wang, X; Xu, Y; Zhang, F | 1 |
| Chappell, MC; Gwathmey, TM; Pirro, NT; South, AM | 1 |
| Polak, Y; Speth, RC | 1 |
| Ahmed, A; Hasan, M; Rahman, MM | 1 |
| Amin, S; Bakouny, Z; Bhasin, M; Bhatt, RS; Catalano, P; Chen, CH; Choueiri, TK; Joslin, PN; Khanna, P; McKay, R; Moore, A; Naughton, M; O'Callaghan, C; Saxena, R; Signoretti, S; Soh, HJ; Walther, T | 1 |
| Bernasconi, L; Conen, A; Domenig, O; Gregoriano, C; Haubitz, S; Koch, D; Kutz, A; Mueller, B; Schuetz, P | 1 |
| Broeker, K; Daniel, C; Fuchs, M; Kurtz, A; Schrankl, J; Wagner, C | 1 |
| Alcaro, F; Antonelli, M; Cutuli, SL; Eleuteri, D; Montini, L; Rossi, C | 1 |
| Caroccia, B; Domenig, O; Iacobone, M; Lenzini, L; Piazza, M; Poglitsch, M; Prisco, S; Rossi, GP; Seccia, TM; Torresan, F; Vanderriele, PE | 1 |
| Bernstein, EA; Bernstein, KE; Cao, D; Giani, JF; Gonzalez-Villalobos, RA; Khan, Z; Okwan-Duodu, D; Shen, JZY; Veiras, LC | 1 |
| Hoang, T; Revoori, R; Rianto, F; Sparks, MA | 1 |
| Cantero-Navarro, E; Fernández-Fernández, B; Ortiz, A; Ramos, AM; Rayego-Mateos, S; Rodrigues-Diez, RR; Ruiz-Ortega, M; Sánchez-Niño, MD; Sanz, AB | 1 |
| Addai, D; Alexandrova, R; Ananiev, J; Rashev, P; Todev, A; Tolekova, A; Uzunova, VV; Zarkos, J | 1 |
| Batlle, D; Soler, MJ | 1 |
| Arfsten, H; Bartko, PE; Domenig, O; Goliasch, G; Hengstenberg, C; Hülsmann, M; Mascherbauer, J; Pavo, N; Poglitsch, M; Prausmüller, S; Spinka, G; Strunk, G; Uyanik-Ünal, K; Wurm, R; Zuckermann, A | 1 |
| Gao, L; Jin, J; Liu, P; Xie, X | 1 |
| Brouqui, P; Devaux, CA; La Scola, B; Lagier, JC; Meddeb, L; Mege, JL; Melenotte, C; Million, M; Osman, IO; Parola, P; Raoult, D; Stein, A | 1 |
| Haddad, F; Hatam, M; Mirzaei-Damabi, N; Nasimi, A; Rostami, B | 1 |
| Abreu, MAD; de Oliveira, TA; Moreira, FRC; Ramos, NE; Simões E Silva, AC | 1 |
| Galal, SM; Hasan, HF; Mohmed, HK | 1 |
| Balachandran, K; Ozkizilcik, A; Patel, S; Sysavanh, F; Tandon, I | 1 |
| Benetti, A; Caramelli, B; Girardi, ACC; Krieger, JE; Malagrino, PA; Martins, FL; Pereira, GMD; Rentz, T; Rios, TMS; Tavares, CAM; Teixeira, SK | 1 |
| Boytsova, EB; Lopatina, OL; Morgun, AV; Salmin, VV; Salmina, AB | 1 |
| Colombo, D; Del Nonno, F; Gheblawi, M; Kassiri, Z; MacIntyre, E; Munan, M; Nikhanj, A; O'Neil, C; Oudit, GY; Poglitsch, M; Sligl, W; Wang, K | 1 |
| Javanmardi, K; Soltani Hekmat, A | 1 |
| Cao, L; Chen, Y; Fan, J; Liu, Y; Lu, L; Yin, Y | 1 |
| Bartosova, L; Galis, P; Goncalvesova, E; Klimas, J; Paulis, L; Rajtik, T | 1 |
| Kuruppu, S; Rajapakse, NW; Tran, S | 1 |
| Ahmad, S; Ferrario, CM; Figueroa, JP; Groban, L; Meredith, JW; Saha, A; VonCannon, JL; Wright, KN; Zhang, J | 1 |
| Belfiore, A; Cammalleri, M; Chiurazzi, M; Colantuoni, A; Dal Monte, M; Damiano, S; De Conno, B; Di Maro, M; Guida, B; Lapi, D; Mondola, P; Nasti, G; Santillo, M; Serao, N; Trio, R | 1 |
| Carletti, R; Castoldi, G; di Gioia, CRT; Ippolito, S; Pelucchi, S; Stella, A; Zatti, G; Zerbini, G | 1 |
| Alfie, J; Corradi, GR; Falcoff, NL; Gironacci, MM; Guman, GR; Iglesias, LI; Nuñez, M; Seguel, RF; Silva, MG; Tabaj, GC | 1 |
| De la Cuesta, F; Peiró, C; Romero, A; Sánchez-Ferrer, CF; Shamoon, L | 1 |
| Gallagher, PE; Grier, RDM; Melo, AC; Rahimi, O; Tallant, EA; Westwood, B | 1 |
| Annoni, F; Caruso, E; Moro, F; Taccone, FS; Zanier, ER; Zoerle, T | 1 |
| Ceroni, A; Manica, LA; Michelini, LC; Raquel, HA | 1 |
| Abi Khattar, Z; Annweiler, C; Cao, Z; El-Arif, G; Fajloun, Z; Farhat, A; Harb, J; Khazaal, S; Kovacic, H; Sabatier, JM; Wu, Y | 1 |
| Cui, T; Guo, Y; Hu, W; Li, C; Liu, R; Wang, X; Yin, C | 1 |
| Abdel Hafez, SMN; Abdel-Hakeem, EA; Abdel-Hamid, HA; Kamel, BA | 1 |
| Chiong, M; Hernandez-Fuentes, C; Lavandero, S; Lopez-Crisosto, C; Martinez-Bilbao, J; Norambuena-Soto, I; Parra, V | 1 |
| Almeida-Santos, AF; Colpo, GD; Furr Stimming, E; Guatimosim, C; Joviano-Santos, JV; Kangussu, LM; Latham, LB; Machado, TCG; Miranda, AS; Rocha, NP; Simões E Silva, AC; Soares, KB; Teixeira, AL; Valadão, PAC | 1 |
| Banerjee, A; Baptista, L; Buford, TW; Carter, CS; Hernandez, A; Li, Q; Sun, Y; Verma, A; Yang, Y | 1 |
| Choopani, S; Nematbakhsh, M | 1 |
| Aileru, A; Byrum, R; Diz, D; Peele, K; Swami Vetha, BS | 1 |
| Gupta, S; Hanif, K; Shukla, S; Tiwari, P; Tiwari, V | 1 |
| Chen, F; Hou, Z; Liu, G; Lu, Y; Lv, X; Xing, C; Zhang, C; Zhang, D | 1 |
| Adin, DB; Hernandez, JA | 1 |
| Aberle, JH; Abrahamowicz, A; Binder, C; Bonderman, D; Domenig, O; Eskandary, F; Gorkiewicz, G; Hecking, M; Heinzel, A; Hödlmoser, S; Jilma, B; Karolyi, M; König, F; Krenn, K; Krenn, S; Mayfurth, H; Mußnig, S; Oberbauer, R; Poglitsch, M; Puchhammer-Stöckl, E; Rathkolb, V; Reindl-Schwaighofer, R; Rumpf, B; Schmölz, L; Schörgenhofer, C; Strassl, R; Tinhof, V; Traugott, MT; Ullrich, R; Wenisch, C; Zoufaly, A | 1 |
| Ballasy, NN; Belke, D; Fedak, PWM; Gomes, KP; Jadli, AS; Mackay, CDA; Meechem, M; Patel, VB; Thompson, J; Wijesuriya, TM | 1 |
| Guatimosim, S; Jesus, ICG; Mesquita, T; Souza Santos, RA | 1 |
| Mogi, M; Nozato, S; Rakugi, H; Takeshita, H; Yamamoto, K | 1 |
| Chaturvedi, S; Gupta, S; Hanif, K; Mishra, A; Shukla, S; Singh, J; Singh, S; Tiwari, P; Tiwari, V; Wahajuddin, M | 1 |
| Chittimalli, K; Ericsson, AC; Jahan, J; Jarajapu, YPR; McAdams, ZL; Sakamuri, A | 1 |
| Bao, X; Fan, H; Wang, Z; Wu, J | 1 |
| Coleman, DM; Dalman, J | 1 |
| Huang, M; Li, W; Song, T; Zhao, M; Zheng, L; Zhou, M | 1 |
| Abassi, Z; Aronson, D; Cohen-Segev, R; Hamoud, S; Kabala, A; Karram, T; Kinaneh, S; Nativ, O | 1 |
| Gan, PXL; Liao, W; Linke, KM; Mei, D; Wong, WSF; Wu, XD | 1 |
| Alenina, N; Bader, M; Beier, SL; Braga, JF; de Oliveira, ML; de Sousa, FG; Lautner, RQ; Santos, R; Todiras, M; Velloso, EPP; Vieira Pimentel, RL | 1 |
| Aryal, S; Joe, B; Lai, K; Li, Q; Manandhar, I; Mei, X; Mell, B; Tummala, R; Yang, T; Yeoh, BS; Zubcevic, J | 1 |
188 review(s) available for angiotensin ii and angiotensin i
| Article | Year |
|---|---|
ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular Diseases; Humans; Hypertension; Kidney Diseases; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Rats; Renin-Angiotensin System | 2015 |
Angiotensin-converting enzyme 2-Angiotensin 1-7/1-9 system: novel promising targets for heart failure treatment.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Agents; Heart Failure; Humans; Molecular Mimicry; Molecular Targeted Therapy; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Treatment Outcome | 2018 |
Hypertension regulating angiotensin peptides in the pathobiology of cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Peptide Fragments; Protective Factors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2018 |
Humoral and neurohormonal aspects of blood pressure regulation: focus on angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Brain Chemistry; Cerebral Ventricles; Kidney; Neurotransmitter Agents; Renin | 1978 |
Is the lung a para-endocrine organ?
Topics: Adenine Nucleotides; Angiotensin I; Angiotensin II; Animals; Bradykinin; Capillaries; Endocrine Glands; Endothelium; Hormones; Humans; Lung; Peptidyl-Dipeptidase A; Pinocytosis; Pulmonary Circulation | 1977 |
Renin-angiotensin system in hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Blood Pressure; Chemical Phenomena; Chemistry; Humans; Hypertension; Hypertension, Renal; Peptidyl-Dipeptidase A; Renin; Sodium | 1979 |
Significance of renin and angiotensin in hypertension.
Topics: Adenoma; Adrenal Cortex Neoplasms; Aldosterone; Angiotensin I; Angiotensin II; Female; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renal; Kidney Neoplasms; Pregnancy; Pregnancy Complications, Cardiovascular; Renal Artery Obstruction; Renal Dialysis; Renin; Sodium | 1978 |
Angiotensin receptor subtypes in the brain.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Drinking; Humans; Natriuresis; Receptors, Angiotensin; Signal Transduction; Vasopressins | 1992 |
The myocardial renin-angiotensin system: existence, importance, and clinical implications.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Myocardial Contraction; Myocardium; Renin-Angiotensin System | 1992 |
Twenty years of investigating angiotensin activity: an overview.
Topics: Angiotensin I; Angiotensin II; Electrolytes; Humans; Receptors, Angiotensin; Renin-Angiotensin System | 1991 |
Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1991 |
Angiotensin-(1-7): a new hormone of the angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Biotransformation; Humans; Peptide Fragments; Renin; RNA, Messenger | 1991 |
Renal metabolism of angiotensin I and II.
Topics: Angiotensin I; Angiotensin II; Humans; Kidney; Kidney Tubules, Proximal; Neprilysin; Peptidyl-Dipeptidase A | 1990 |
Pathways of angiotensin formation and function in the brain.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Humans; Models, Biological; Peptide Fragments | 1990 |
Effects of angiotensin converting enzyme inhibition: a clinical point of view.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Circulation; Blood Pressure; Bradykinin; Brain; Heart Rate; Humans; Hypertension; Renin-Angiotensin System; Sodium | 1985 |
Immunologic approaches to blockade of the renin-angiotensin system: a review.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Humans; Hypertension; Immunization, Passive; Immunotherapy; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1989 |
Experience with perindopril in normal volunteers.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Drug Administration Schedule; Humans; Indoles; Peptidyl-Dipeptidase A; Perindopril; Renin-Angiotensin System | 1989 |
Cellular organization of the brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Brain; Immunohistochemistry; Models, Biological; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1987 |
The renin-angiotensin system and body function.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Brain; Hemorrhage; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Pituitary Gland; Renin; Renin-Angiotensin System; Water-Electrolyte Balance | 1985 |
Pharmacology of angiotensin converting enzyme inhibitors. A review.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Binding Sites; Blood Pressure; Captopril; Eating; Enalapril; Half-Life; Humans; Intestinal Absorption; Kinetics; Oligopeptides; Peptidyl-Dipeptidase A; Renin; Teprotide | 1986 |
Renin and reproduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Extraembryonic Membranes; Female; Genitalia, Female; Humans; Hypertension; Menstrual Cycle; Ovary; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Prostaglandins; Rabbits; Renin; Reproduction; Research | 1988 |
Control of intestinal absorption by the renin-angiotensin system.
Topics: Adrenalectomy; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Hemodynamics; Humans; In Vitro Techniques; Intestinal Absorption; Intestines; Kallikreins; Kinins; Nephrectomy; Renin-Angiotensin System; Seasons; Sympathetic Nervous System | 1985 |
The site of angiotensin production.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Humans; Hypertension; Renin-Angiotensin System; Sheep | 1985 |
An overview of the clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Dipeptides; Drug Administration Schedule; Enalapril; Enalaprilat; Heart Failure; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Norepinephrine; Prostaglandins; Renal Circulation; Renin | 1984 |
Measurement of the hormones of the renin system in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Volume; Body Water; Diuretics; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Kidney; Methods; Regional Blood Flow; Renal Veins; Renin; Sodium; Vasoconstriction | 1981 |
[Role of peptidases in regulating vascular tonus].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Endopeptidases; Humans; In Vitro Techniques; Kinins; Peptidyl-Dipeptidase A; Receptors, Bradykinin; Receptors, Cell Surface; Renin-Angiotensin System; Vascular Resistance | 1982 |
The surgical implications of nonrespiratory lung function.
Topics: Adenine Nucleotides; Amines; Anaphylaxis; Angiotensin I; Angiotensin II; Animals; Bradykinin; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Glucuronosyltransferase; Histamine Release; Humans; Inactivation, Metabolic; Lung; NADP; Neurotransmitter Agents; Physical Stimulation; Prostaglandins; SRS-A; Stimulation, Chemical | 1980 |
[The renin-angiotensin system. Physiopathological aspects and clinical implications of hypertensive syndromes. A survey].
Topics: Acromegaly; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Cushing Syndrome; Glycoproteins; Humans; Hyperaldosteronism; Hypertension; Kidney; Kidney Diseases; Prostaglandins; Receptors, Adrenergic; Receptors, Angiotensin; Renin; Sodium; Sympathetic Nervous System; Teprotide | 1981 |
[Renin-angiotensin system blockers].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Animals; Humans; Hypertension; Kidney; Oligopeptides; Pepstatins; Renin; Renin-Angiotensin System; Teprotide | 1982 |
Inhibition of renin: recent developments.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Callithrix; Chemical Phenomena; Chemistry; Dogs; Horses; Humans; Macaca fascicularis; Oligopeptides; Papio; Pepstatins; Rats; Renin; Renin-Angiotensin System; Teprotide | 1984 |
Angiotensin II and renal hypertension in dog, rat and man: effect of converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Female; Furosemide; Humans; Hypertension, Renal; Male; Middle Aged; Potassium; Proline; Radioimmunoassay; Rats; Renal Artery Obstruction; Renin; Saralasin; Sodium | 1980 |
Drugs inhibiting the renin - angiotensin system.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Cardiac Output; Dogs; Hypertension; Lipids; Pepstatins; Phospholipids; Rats; Renin; Structure-Activity Relationship; Substrate Specificity | 1981 |
[Cerebral renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Cattle; Dogs; Humans; Mice; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Thirst | 1983 |
The renin angiotensin system--its physiology and role in disease states.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Diagnosis; Humans; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 1983 |
The brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Biogenic Amines; Blood Pressure; Blood-Brain Barrier; Brain; Brain Chemistry; Cerebrospinal Fluid; Dogs; Endopeptidases; Histocytochemistry; Humans; Immunologic Techniques; Peptidyl-Dipeptidase A; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 1984 |
Renin in the brain and neuroblastoma cells: an endogenous and intracellular system.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Brain; Cathepsin D; Cathepsins; Cell Line; Chemical Phenomena; Chemistry, Physical; Chromatography, Affinity; Histocytochemistry; Hydrogen-Ion Concentration; Hypertension; Immunologic Techniques; Mice; Nephrectomy; Neuroblastoma; Rats; Renin; Tissue Distribution | 1982 |
Possible hormonal role of the angiotensin-like peptides in mammals' pineal gland.
Topics: Angiotensin I; Angiotensin II; Animals; Endopeptidases; Hormones; Peptides; Pineal Gland; Renin; Serotonin | 1981 |
Hydrolysis and transport of small peptides by the proximal tubule.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Animals; Biological Transport; Carbon Radioisotopes; Cell Membrane; Intestinal Mucosa; Kidney Tubules, Proximal; Microvilli; Peptides; Rats | 1980 |
Effects of captopril in animal models of hypertension.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Bradykinin; Captopril; Dogs; Hemodynamics; Hydralazine; Hydrochlorothiazide; Hypertension; Kallikreins; Kidney; Proline; Prostaglandins; Rabbits; Rats; Renin; Sodium | 1980 |
[Alternative pathways of angiotensin I. The glimpse of new possibilities in the treatment of hypertension and heart failure].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Circulation; Blood Pressure; Heart Failure; Humans; Hypertension; Renin-Angiotensin System | 1995 |
The chymase-angiotensin system in humans: biochemistry, molecular biology and potential role in cardiovascular diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Cardiovascular Diseases; Chymases; Heart Diseases; Humans; Hypertension; Molecular Biology; Serine Endopeptidases | 1995 |
Connective tissue and repair in the heart. Potential regulatory mechanisms.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Connective Tissue; Fibrosis; Heart; Hormones; Humans; Models, Cardiovascular; Myocardium; Prostaglandins; Wound Healing | 1995 |
Human angiotensin receptor subtypes.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; DNA, Complementary; Gene Library; Humans; Imidazoles; Losartan; Oligopeptides; Pyridines; Receptors, Angiotensin; Tetrazoles | 1994 |
[Endothelial mechanisms in vasomotor effects of ACE inhibitors].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Culture Techniques; Endothelium, Vascular; Hemodynamics; Humans; Nitric Oxide; Peptide Fragments; Receptors, Bradykinin; Vasomotor System | 1994 |
The intrarenal renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Humans; Kidney; Renin; Renin-Angiotensin System | 1993 |
A new myocardial conversion of angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Chymases; Coronary Artery Disease; Heart Failure; Humans; Hypertension; Myocardium; Renin-Angiotensin System; Serine Endopeptidases | 1994 |
Central and peripheral actions of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Brain; Medulla Oblongata; Peptide Fragments; Rats; Receptors, Angiotensin; Renin-Angiotensin System | 1994 |
Renin is not synthesized by cardiac and extrarenal vascular tissues. A review of experimental evidence.
Topics: Angiotensin I; Angiotensin II; Animals; Enzyme Precursors; Gene Expression; Gene Expression Regulation; Humans; Kidney; Muscle, Smooth, Vascular; Myocardium; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; RNA, Messenger | 1994 |
Modulation of sympathetic control by ACE inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Epinephrine; Norepinephrine; Sympathetic Nervous System | 1993 |
Angiotensin receptor heterogeneity in the dorsal medulla oblongata as defined by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Genetic Heterogeneity; Medulla Oblongata; Motor Neurons; Neurons, Afferent; Peptide Fragments; Receptors, Angiotensin; Vagus Nerve | 1996 |
Molecular biology of angiotensin receptors and their role in human cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Cardiovascular Diseases; Humans; Receptors, Angiotensin | 1996 |
Hypertension, thermotolerance, and the "African gene": an hypothesis.
Topics: Angiotensin I; Angiotensin II; Black People; Body Temperature Regulation; Gene Deletion; Humans; Hypertension; Mutagenesis, Insertional; Peptidyl-Dipeptidase A; Prevalence; Renin-Angiotensin System; United States | 1996 |
[Angiotensin-2 receptor blockade--new therapeutic approach to treatment of hypertension].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Tetrazoles | 1996 |
The renin-angiotensin system and coronary vasomotion.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Flow Velocity; Cardiomegaly; Coronary Vessels; Dogs; Humans; Hypoxia; In Vitro Techniques; Myocardial Ischemia; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Swine | 1996 |
Is there an internal cardiac renin-angiotensin system?
Topics: Angiotensin I; Angiotensin II; Animals; Humans; Kidney; Myocardium; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Sheep; Swine; Transcription, Genetic | 1996 |
Human type-1 angiotensin II (AT1) receptor gene structure and function.
Topics: Alternative Splicing; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Axons; Humans; Molecular Weight; Open Reading Frames; Polymerase Chain Reaction; Polymorphism, Genetic; Protein Biosynthesis; Receptors, Angiotensin; RNA, Messenger; Transcription, Genetic | 1996 |
Intrarenal production of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Hemodynamics; Humans; Hypertension; Kidney; Rats; Renin-Angiotensin System | 1997 |
Counterregulatory actions of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Endothelium, Vascular; Humans; Kidney; Muscle, Smooth, Vascular; Peptide Fragments; Vasodilator Agents | 1997 |
Expression of angiotensin type-1 (AT1) and type-2 (AT2) receptor mRNAs in the adult rat brain: a functional neuroanatomical review.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Brain Chemistry; Rats; Receptors, Angiotensin; RNA, Messenger | 1997 |
[The renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Homeostasis; Humans; Hypertension; Renin-Angiotensin System; Sodium | 1997 |
[AT1 angiotensin receptor inhibition as a new therapeutic possibility].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Female; Heart Failure; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1997 |
The renin-angiotensin system and vascular function. The role of angiotensin II, angiotensin-converting enzyme, and alternative conversion of angiotensin I.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Brain; Chymases; Endothelium, Vascular; Heart; Humans; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Serine Endopeptidases; Vasoconstriction | 1997 |
Physiological and pharmacological implications of AT1 versus AT2 receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Humans; Kidney; Receptors, Angiotensin | 1998 |
Angiotensin-(1-7): a novel vasodilator of the coronary circulation.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Circulation; Dogs; Peptide Fragments; Vasodilator Agents | 1998 |
Differential actions of angiotensin-(1-7) in the kidney.
Topics: Angiotensin I; Angiotensin II; Humans; Kidney; Peptide Fragments; Renin-Angiotensin System | 1998 |
Gene targeting in physiological investigations: studies of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Gene Targeting; Kidney; Mice; Mice, Transgenic; Mutation; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System | 1998 |
Effect of the angiotensin-(1-7) peptide on nitric oxide release.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Muscle, Smooth, Vascular; Nitric Oxide; Peptide Fragments; Vasoconstrictor Agents; Vasodilation | 1998 |
Antihypertensive effects of angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Hypertension; Peptide Fragments; Renin-Angiotensin System | 1998 |
Angiotensin-(1-7): a bioactive fragment of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System | 1998 |
The relative roles of circulating and tissue renin-angiotensin systems.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Humans; Renin; Renin-Angiotensin System | 1999 |
Chymase: its pathophysiological roles and inhibitors.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Diseases; Chymases; Cytokines; Humans; Inflammation; Peptidyl-Dipeptidase A; Serine Endopeptidases; Serine Proteinase Inhibitors; Species Specificity; Structure-Activity Relationship | 1998 |
Intrarenal angiotensin II generation and renal effects of AT1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Natriuresis; Rats; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Tetrazoles | 1999 |
Renin-angiotensin systems and reproduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Humans; Male; Mice; Rats; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Reproduction | 1999 |
[Hypertension therapy and molecular biology--with special reference to renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension | 1999 |
Hypertension as a paraneoplastic syndrome in hepatocellular carcinoma.
Topics: Aged; Angiotensin I; Angiotensin II; Carcinoma, Hepatocellular; Fatal Outcome; Humans; Hypertension; Hypoglycemia; Liver Neoplasms; Male; Paraneoplastic Syndromes; Renin; Tomography, X-Ray Computed; Ultrasonography | 1999 |
[Pathophysiological roles of chymase and effects of chymase inhibitor].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chymases; Chymotrypsin; Cricetinae; Dogs; Enzyme Inhibitors; Humans; Hypertension; Neovascularization, Physiologic; Oligopeptides; Rats; Serine Endopeptidases; Serine Proteinase Inhibitors; Species Specificity; Vasoconstriction | 1999 |
Prothrombotic effects of angiotensin.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Blood Coagulation; Blood Platelets; Bradykinin; Fibrinolysis; Fibrinolytic Agents; Free Radical Scavengers; Humans; Nitric Oxide; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Renin-Angiotensin System; Serine Proteinase Inhibitors; Superoxides; Thrombosis; Tissue Plasminogen Activator | 2000 |
Is there a local renin-angiotensin system in the heart?
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Cell Membrane; Cells, Cultured; Humans; Intracellular Fluid; Mannosephosphates; Myocardium; Peptidyl-Dipeptidase A; Perfusion; Renin; Renin-Angiotensin System | 1999 |
Interactions among ACE, kinins and NO.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteriosclerosis; Biological Availability; Cardiovascular Diseases; Endothelium, Vascular; Humans; Hypertension; Kinins; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Ventricular Remodeling | 1999 |
[Angiotensin I, angiotensin II, angiotensin III].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Humans | 1999 |
The physiological role of AT1 receptors in the ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Blood Pressure; Cardiovascular Physiological Phenomena; Heart Rate; Humans; Kidney; Medulla Oblongata; Neurons; Rabbits; Receptors, Angiotensin; Sympathetic Nervous System; Vasoconstrictor Agents | 2000 |
Angiotensin-(1-7): an update.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Central Nervous System; Humans; Kidney; Losartan; Models, Biological; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 2000 |
Angiotensin II type 1 receptor blockers.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Blood Pressure; Drug Design; Humans; Irbesartan; Losartan; Peptidyl-Dipeptidase A; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Saralasin; Tetrazoles; Valine; Valsartan | 2001 |
Angiotensin receptors: distribution, signalling and function.
Topics: Angiotensin I; Angiotensin II; Animals; Humans; Mice; Mice, Knockout; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 2001 |
Regulation of the renal proximal tubule second sodium pump by angiotensins.
Topics: Angiotensin I; Angiotensin II; Animals; Extracellular Space; Kidney Tubules, Proximal; Receptors, Angiotensin; Sodium; Sodium-Potassium-Exchanging ATPase | 2001 |
Interactions between angiotensin-(1-7), kinins, and angiotensin II in kidney and blood vessels.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Humans; Kidney; Kinins; Models, Biological; Peptide Fragments; Renin-Angiotensin System | 2001 |
New insights into actions of the renin-angiotensin system in the kidney: concentrating on the Ang II receptors and the newly described Ang-(1-7) and its receptor.
Topics: Angiotensin I; Angiotensin II; Humans; Kidney; Peptide Fragments; Receptors, Angiotensin; Renin-Angiotensin System | 2001 |
The protective effect of blocking angiotensin in both type I and type II diabetics with nephropathy.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Irbesartan; Losartan; Male; Middle Aged; Primary Prevention; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Tetrazoles; Treatment Outcome | 2001 |
Angiotensin I, angiotensin II and their biologically active peptides.
Topics: Angiotensin I; Angiotensin II; Humans; Peptide Fragments | 2002 |
Dissecting the role of chymase in angiotensin II formation and heart and blood vessel diseases.
Topics: Angiotensin I; Angiotensin II; Arteriosclerosis; Cardiomegaly; Cardiovascular Diseases; Chymases; Heart Diseases; Heart Failure; Humans; Hypertension; Peptidyl-Dipeptidase A; Serine Endopeptidases | 2002 |
Effect of chymase inhibitor on vascular proliferation.
Topics: Angioplasty, Balloon; Angiotensin I; Angiotensin II; Animals; Arteries; Cell Division; Chymases; Dogs; Mast Cells; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Serine Endopeptidases; Serine Proteinase Inhibitors; Veins | 2002 |
Angiotensin-converting enzyme inhibitors: mechanisms of action and implications in anesthesia practice.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Renin-Angiotensin System | 2003 |
Cellular targets for angiotensin II fragments: pharmacological and molecular evidence.
Topics: Angiotensin I; Angiotensin II; Animals; Cells; Cystinyl Aminopeptidase; Humans; Peptide Fragments; Receptors, Angiotensin | 2002 |
Angiotensin II dose-effect curves and Schild regression plots for characterization of different angiotensin II AT1 receptor antagonists in clinical pharmacology.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Humans; Receptors, Angiotensin; Regression Analysis | 2003 |
Novel angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Heart; Humans; Kidney; Peptide Fragments; Reproduction | 2004 |
The renin-angiotensin system: peptides and enzymes beyond angiotensin II.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Animals; Humans; Peptide Fragments; Renin-Angiotensin System | 2005 |
Involvement of placental peptidases associated with renin-angiotensin systems in preeclampsia.
Topics: Angiotensin I; Angiotensin II; Cell Hypoxia; Female; Glutamyl Aminopeptidase; Humans; Peptidyl-Dipeptidase A; Placenta; Placental Circulation; Pre-Eclampsia; Pregnancy; Renin-Angiotensin System | 2005 |
[The renin-angiotensin-aldosterone system -- more complex as previously thought].
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chronic Disease; Chymases; Clinical Trials as Topic; Diabetic Nephropathies; Disease Progression; Drug Therapy, Combination; Humans; Indoles; Kidney Diseases; Kidney Tubules, Proximal; Losartan; Prospective Studies; Receptors, Angiotensin; Renin-Angiotensin System; Risk Factors; Serine Endopeptidases | 2005 |
[Angiotensin I, angiotensin II, angiotensin III].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Biomarkers; Chromatography, High Pressure Liquid; Cushing Syndrome; Diagnosis, Differential; Diagnostic Techniques, Endocrine; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Myocardial Infarction; Radioimmunoassay; Reference Values; Renin-Angiotensin System; Specimen Handling; Water-Electrolyte Imbalance | 2005 |
Angiotensin and diabetic retinopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Diabetic Retinopathy; Humans; Hypertension; Neovascularization, Pathologic; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Retina | 2006 |
Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fibrosis; Humans; Hyperglycemia; Hypoglycemia; Islets of Langerhans; Pancreas; Peptidyl-Dipeptidase A; PPAR gamma; Receptors, Angiotensin; Renin; Renin-Angiotensin System | 2006 |
Macroangiopathy in adults and children with diabetes: from molecular mechanisms to vascular damage (part 1).
Topics: Adult; Angiotensin I; Angiotensin II; Atherosclerosis; Child; Cholesterol, LDL; Diabetic Angiopathies; Fatty Liver; Humans; Inflammation; Macrophages; Thrombosis | 2006 |
Opposite effects of angiotensin II and angiotensin (1-7) on impulse propagation, excitability and cardiac arrhythmias. Is the overexpression of ACE2 arrhythmogenic?
Topics: Action Potentials; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arrhythmias, Cardiac; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction | 2009 |
Regulatory mechanisms of atrial fibrotic remodeling in atrial fibrillation.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Atrial Fibrillation; Endomyocardial Fibrosis; Heart Atria; Humans; Inflammation; Matrix Metalloproteinases; Models, Biological; Oxidative Stress; Peptide Fragments; ras GTPase-Activating Proteins; Signal Transduction; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta1; Ventricular Remodeling | 2008 |
Angiotensin-converting enzyme 2: possible role in hypertension and kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Biological Assay; Humans; Hypertension; Kidney; Kidney Diseases; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2008 |
Liver disease and the renin-angiotensin system: recent discoveries and clinical implications.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Humans; Hypertension, Portal; Kallikreins; Kinins; Liver; Liver Cirrhosis; Liver Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2008 |
Pharmacologic modulation of ACE2 expression.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Disease Progression; Humans; Hypertension; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2008 |
Renin-angiotensin system revisited.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System; Vacuolar Proton-Translocating ATPases | 2008 |
The renin-angiotensin system and diabetes: an update.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Diabetes Mellitus; Endothelium, Vascular; Humans; Hyaluronan Receptors; Insulin; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Signal Transduction | 2008 |
Immunization against angiotensins for the treatment of hypertension.
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Humans; Hypertension; Renin-Angiotensin System; Treatment Outcome; Vaccination; Vaccines | 2010 |
Regulation of central angiotensin type 1 receptors and sympathetic outflow in heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Chronic Disease; Exercise; Heart; Heart Failure; Humans; Medulla Oblongata; Neurons; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Transcription Factor AP-1; Transcription, Genetic; Up-Regulation | 2009 |
Dual blockade of the renin-angiotensin system in diabetic nephropathy.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Humans; Meta-Analysis as Topic; Renin-Angiotensin System | 2009 |
Mechanisms of proximal tubule sodium transport regulation that link extracellular fluid volume and blood pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Extracellular Fluid; Homeostasis; Humans; Kidney Tubules, Proximal; Natriuresis; Renal Circulation; Sodium; Sodium-Hydrogen Exchangers | 2010 |
The ANG-(1-7)/ACE2/mas axis in the regulation of nephron function.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nephrons; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2010 |
Vaccines in the management of hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Oligopeptides; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Treatment Outcome; Vaccines | 2010 |
ACE2: more of Ang-(1-7) or less Ang II?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2011 |
Endogenous angiotensin II levels and the mechanism of action of angiotensin-converting enzyme inhibitors and angiotensin receptor type 1 antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Humans; Receptor, Angiotensin, Type 1 | 1996 |
Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Cardiovascular Diseases; Humans; Neurons; Nitric Oxide; Oxidation-Reduction; Peptide Fragments; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase | 2011 |
Angiotensin peptides and central autonomic regulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Baroreflex; Blood Pressure; Brain; Humans; Hypertension; MAP Kinase Signaling System; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol 3-Kinases | 2011 |
Do genetic variants of the Renin-Angiotensin system predict blood pressure response to Renin-Angiotensin system-blocking drugs?: a systematic review of pharmacogenomics in the Renin-Angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Genetic Variation; Humans; Hypertension; Peptidyl-Dipeptidase A; Pharmacogenetics; Polymorphism, Genetic; Renin-Angiotensin System | 2011 |
Role of ACE2 in diastolic and systolic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Heart Failure; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction | 2012 |
New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cystinyl Aminopeptidase; Humans; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Transgenic; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction | 2011 |
Alternative pathways for angiotensin II generation in the cardiovascular system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular System; Chymases; Humans; Mice; Rats; Renin-Angiotensin System; Serine Endopeptidases | 2011 |
Role of angiotensin in ovarian follicular development and ovulation in mammals: a review of recent advances.
Topics: Angiotensin I; Angiotensin II; Animals; Autocrine Communication; Cattle; Female; Models, Biological; Ovarian Follicle; Ovulation; Paracrine Communication; Peptide Fragments; Rabbits; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction | 2012 |
[Research progress in relations between renin angiotensin system and diabetic cardiomyopathy].
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Diabetic Cardiomyopathies; Humans; NF-kappa B; Oligopeptides; Peptide Fragments; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2011 |
Angiotensin-converting enzyme 2: enhancing the degradation of angiotensin II as a potential therapy for diabetic nephropathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetic Nephropathies; Humans; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
Angiotensin peptides and nitric oxide in cardiovascular disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cardiovascular Diseases; Heart Failure; Humans; Nitric Oxide; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2013 |
Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin-angiotensin system: a patent review.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Agents; Drug Design; Enzyme Activation; Enzyme Activators; Humans; Legislation, Drug; Molecular Structure; Patents as Topic; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Structure-Activity Relationship | 2012 |
The renin-angiotensin system, bone marrow and progenitor cells.
Topics: Adipogenesis; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bone Marrow; Erythropoiesis; Hematopoiesis; Humans; Kidney; Mesenchymal Stem Cells; Metabolic Syndrome; Myocytes, Cardiac; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stem Cells; Tetrazoles; Valine; Valsartan | 2012 |
The role of the renin-angiotensin system in the development of insulin resistance in skeletal muscle.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport, Active; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin Resistance; Insulin-Secreting Cells; Muscle, Skeletal; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2013 |
Angiotensin (1-7) and other angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Glucose; Humans; Kidney Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2013 |
The renin angiotensin aldosterone system and insulin resistance in humans.
Topics: Adipose Tissue; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Glucose; Hemodynamics; Humans; Insulin Resistance; Models, Animal; Muscle, Skeletal; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2013 |
Pathophysiological role of the renin-angiotensin system on erectile dysfunction.
Topics: Angiotensin I; Angiotensin II; Erectile Dysfunction; Humans; Male; Penile Erection; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2013 |
Interactions of neuropeptide y, catecholamines, and angiotensin at the vascular neuroeffector junction.
Topics: Angiotensin I; Angiotensin II; Animals; Catecholamines; Humans; Hypertension; Neuroeffector Junction; Neuropeptide Y; Peptide Fragments; Sympathetic Nervous System | 2013 |
Modulation of the action of insulin by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction | 2014 |
ACE2: angiotensin II/angiotensin-(1-7) balance in cardiac and renal injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Heart Diseases; Humans; Hypertension; Kidney Diseases; Peptide Fragments; Peptidyl-Dipeptidase A | 2014 |
New components of the renin-angiotensin system: alamandine and the MAS-related G protein-coupled receptor D.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Oligopeptides; Peptide Fragments; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Risk Assessment; Sensitivity and Specificity | 2014 |
Protective axis of the renin-angiotensin system in the brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Blood Pressure; Brain; Neurotransmitter Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction | 2014 |
How to design a potent, specific, and stable angiotensin-converting enzyme inhibitor.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Drug Design; Humans; Peptidyl-Dipeptidase A; Quantitative Structure-Activity Relationship | 2014 |
ACE and ACE2 in inflammation: a tale of two enzymes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
Counter-regulatory effects played by the ACE - Ang II - AT1 and ACE2 - Ang-(1-7) - Mas axes on the reactive oxygen species-mediated control of vascular function: perspectives to pharmacological approaches in controlling vascular complications.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Humans; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Vascular Diseases | 2014 |
The role of renin-angiotensin system modulation on treatment and prevention of liver diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Humans; Liver Diseases; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2014 |
The intrarenal renin-angiotensin system in hypertension.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Kidney; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sodium | 2015 |
Therapeutic uses for Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Clinical Trials as Topic; Drug Design; Humans; Neoplasms; Patents as Topic; Peptide Fragments; Renin-Angiotensin System | 2016 |
Unraveling the Pivotal Role of Bradykinin in ACE Inhibitor Activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cardiovascular Diseases; Endothelium, Vascular; Humans; Renin-Angiotensin System; Risk Factors; Vasodilation | 2016 |
Role of renin-angiotensin system in liver diseases: an outline on the potential therapeutic points of intervention.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Enzyme Activation; Enzyme Activators; Humans; Liver; Liver Diseases; Molecular Targeted Therapy; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Treatment Outcome | 2016 |
Measurement of Angiotensin Peptides: HPLC-RIA.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Humans; Peptide Fragments; Radioimmunoassay; Renin-Angiotensin System | 2017 |
Angiotensin converting enzymes in fish venom.
Topics: Angiotensin I; Angiotensin II; Animals; Batrachoidiformes; Blood Pressure; Bradykinin; Brazil; Fish Venoms; Homeostasis; Peptidyl-Dipeptidase A | 2017 |
Angiotensin II and skeletal muscle abnormalities.
Topics: Angiotensin I; Angiotensin II; Animals; Chronic Disease; Exercise; Humans; Muscle, Skeletal; Weight Loss | 2017 |
Renin-Angiotensin System in Diabetes.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus; Humans; Peptide Fragments; Renin-Angiotensin System | 2017 |
Physical Exercise and ACE2-Angiotensin-(1-7)-Mas Receptor Axis of the Renin Angiotensin System.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Exercise; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Vasoconstriction | 2017 |
Cognitive benefits of angiotensin IV and angiotensin-(1-7): A systematic review of experimental studies.
Topics: Angiotensin I; Angiotensin II; Animals; Cognition Disorders; Databases, Bibliographic; Dementia; Disease Models, Animal; Humans; Memory, Short-Term; Peptide Fragments | 2018 |
The renin-angiotensin system as a target to solve the riddle of endocrine pancreas homeostasis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Drug Delivery Systems; Homeostasis; Humans; Insulin Resistance; Islets of Langerhans; Peptide Fragments; Renin-Angiotensin System | 2019 |
ACE2 in Brain Physiology and Pathophysiology: Evidence from Transgenic Animal Models.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Brain; Brain Diseases; Cardiomegaly; Models, Animal; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Serotonin; Stress, Psychological; Tryptophan | 2019 |
The Protective Arm of Renin Angiotensin System; Recent Research Progress and Expectation for New Therapeutic Approach.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2016 |
Classic and Nonclassic Renin-Angiotensin Systems in the Critically Ill.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Blood Pressure; Critical Illness; Female; Homeostasis; Humans; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Respiratory Distress Syndrome; Shock, Septic; Vasoconstrictor Agents | 2019 |
Levels of angiotensin peptides in healthy and cardiovascular/renal-diseased paediatric population-an investigative review.
Topics: Adolescent; Age Factors; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Hypertension; Infant; Infant, Newborn; Kidney Failure, Chronic; Male; Peptide Fragments; Renin-Angiotensin System | 2019 |
Muscle wasting: A review of exercise, classical and non-classical RAS axes.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Exercise; Fibrosis; Humans; Mitochondria; Muscle, Skeletal; Muscular Atrophy; NADPH Oxidases; Peptide Fragments; Protein Biosynthesis; Reactive Oxygen Species; Renin-Angiotensin System; Ubiquitin-Protein Ligases | 2019 |
Angiotensin II and angiotensin 1-7: which is their role in atrial fibrillation?
Topics: Angiotensin I; Angiotensin II; Atrial Fibrillation; Atrial Remodeling; Humans; Peptide Fragments | 2020 |
AMPK: a balancer of the renin-angiotensin system.
Topics: AMP-Activated Protein Kinases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autophagy; Blood Pressure; Blood Vessels; Gene Expression Regulation; Humans; Insulin Resistance; Kidney; Muscle, Skeletal; Myocardium; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction | 2019 |
Effect of renin-angiotensin system on senescence.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cellular Senescence; Humans; Longevity; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Signal Transduction | 2020 |
Potential influence of COVID-19/ACE2 on the female reproductive system.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; Female; Gene Expression Regulation; Genitalia, Female; Host-Pathogen Interactions; Humans; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pregnancy; Protein Binding; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Spike Glycoprotein, Coronavirus | 2020 |
The Network of Angiotensin Receptors in Breast Cancer.
Topics: Angiotensin I; Angiotensin II; Breast Neoplasms; Female; Humans; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2020 |
The ACE2/Ang (1-7)/MasR axis as an emerging target for antihypertensive peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Vasodilation | 2021 |
Angiotensin-Converting Enzyme Gene Polymorphism and Severe Lung Injury in Patients with Coronavirus Disease 2019.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Lung Injury; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; Polymorphism, Genetic; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2 | 2020 |
ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Humans; Muscle, Skeletal; Peptide Fragments; SARS-CoV-2 | 2020 |
Coronavirus Disease 2019 and Hypertension: The Role of Angiotensin-Converting Enzyme 2 and the Renin-Angiotensin System.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Comorbidity; COVID-19; Humans; Hypertension; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Peptide Fragments; Protective Factors; Receptors, Coronavirus; Renin-Angiotensin System; Risk Factors; SARS-CoV-2; Up-Regulation | 2020 |
The Angiotensin-(1-12)/Chymase axis as an alternate component of the tissue renin angiotensin system.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biocatalysis; Bone Marrow; Brain; Cardiovascular Diseases; Chymases; Gene Expression; Humans; Intestines; Kidney; Myocardium; Peptide Fragments; Rats; Renin-Angiotensin System | 2021 |
Molecular pathways triggered by COVID-19 in different organs: ACE2 receptor-expressing cells under attack? A review.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Atrial Fibrillation; Blood Coagulation; Capillary Permeability; Cardiomyopathies; COVID-19; Cytokine Release Syndrome; Cytokines; Endothelium, Vascular; Fibroblasts; Fibrosis; Humans; Liver Cirrhosis; Myocarditis; Receptors, Coronavirus; Renin-Angiotensin System; SARS-CoV-2; Systemic Inflammatory Response Syndrome; Thrombosis; Virus Internalization | 2020 |
Research Progress on Pulmonary Arterial Hypertension and the Role of the Angiotensin Converting Enzyme 2-Angiotensin-(1-7)-Mas Axis in Pulmonary Arterial Hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Arterial Hypertension; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2022 |
Potential detrimental role of soluble ACE2 in severe COVID-19 comorbid patients.
Topics: ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Comorbidity; COVID-19; Humans; Peptide Fragments; SARS-CoV-2 | 2021 |
Novel roles of the renal angiotensin-converting enzyme.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Mice; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Kidney Tubules, Proximal; Mice; Mice, Knockout; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Insufficiency, Chronic; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Renin-angiotensin system and inflammation update.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoimmunity; Blood Pressure; Gene Expression Regulation; Humans; Inflammation; Kidney; Klotho Proteins; Peptide Fragments; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; T-Lymphocytes; Water-Electrolyte Balance | 2021 |
The role of renin angiotensin system in the pathophysiology of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Osteoarthritis; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Treatment Outcome | 2021 |
Evolutionary trilogy of malaria, angiotensin II and hypertension: deeper insights and the way forward.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Malaria; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin-Angiotensin System | 2022 |
Molecular Mechanisms of Proteins - Targets for SARS-CoV-2 (Review).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Astrocytes; Basigin; Brain; COVID-19; Humans; Peptide Fragments; SARS-CoV-2; Serine Endopeptidases | 2021 |
Alamandine: Potential Protective Effects in SARS-CoV-2 Patients.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Humans; Oligopeptides; Peptide Fragments; Renin-Angiotensin System | 2021 |
Alternative RAS in Various Hypoxic Conditions: From Myocardial Infarction to COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; COVID-19; Humans; Hypoxia; Lung; Myocardial Infarction; Peptide Fragments; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Cytokines; Dementia, Vascular; Humans; Hypertension; Inflammation; Peptide Fragments; Renin-Angiotensin System | 2022 |
Angiotensin-(1-7) reduces doxorubicin-induced aortic arch dysfunction in male and female juvenile Sprague Dawley rats through pleiotropic mechanisms.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Doxorubicin; Female; Humans; Male; Peptide Fragments; Pulse Wave Analysis; Rats; Rats, Sprague-Dawley | 2022 |
Angiotensin-(1-7) as a Potential Therapeutic Strategy for Delayed Cerebral Ischemia in Subarachnoid Hemorrhage.
Topics: Angiotensin I; Angiotensin II; Brain Ischemia; Humans; Peptide Fragments; Subarachnoid Hemorrhage | 2022 |
Angiotensin II Type I Receptor (AT1R): The Gate towards COVID-19-Associated Diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; COVID-19 Drug Treatment; Humans; Receptor, Angiotensin, Type 1; SARS-CoV-2 | 2022 |
Angiotensin-(1-9) in hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Hypertension; Imidazoles; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sulfonamides; Thiophenes | 2022 |
Sex Difference in MasR Expression and Functions in the Renal System.
Topics: Angiotensin I; Angiotensin II; Female; Humans; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Sex Characteristics | 2022 |
An overview of alamadine/MrgD signaling and its role in cardiomyocytes.
Topics: Angiotensin I; Angiotensin II; Myocytes, Cardiac; Peptide Fragments; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction | 2023 |
Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?-Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2023 |
Nonatherosclerotic Renovascular Hypertension.
Topics: Angiotensin I; Angiotensin II; Blood Pressure; Humans; Hypertension; Hypertension, Renovascular; Renin; Sodium | 2023 |
81 trial(s) available for angiotensin ii and angiotensin i
| Article | Year |
|---|---|
Long-term effects of captopril (SQ14 225) on blood-pressure and hormone levels in essential hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Drug Synergism; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Potassium; Proline; Renin | 1979 |
Hormonal changes with long-term converting-enzyme inhibition by captopril in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Potassium; Proline; Renin | 1979 |
Clinical experience with angiotensin II receptor antagonists.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Imidazoles; Injections, Intravenous; Losartan; Renin-Angiotensin System; Tetrazoles; Time Factors | 1992 |
Reactive hyperreninemia is a major determinant of plasma angiotensin II during ACE inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Humans; Indoles; Iodine Radioisotopes; Renin; Renin-Angiotensin System | 1990 |
Effect of the renin response during renin inhibition: oral Ro 42-5892 in normal humans.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Blood Pressure; Heart Rate; Humans; Imidazoles; Injections, Intravenous; Male; Renin; Single-Blind Method | 1991 |
Nonparallel effects of renin inhibitor treatment on plasma renin activity and angiotensins I and II in hypertensive subjects. An assay-related artifact.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1991 |
Renin release regulation during acute renin inhibition in normal volunteers.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Heart Rate; Humans; Imidazoles; Infusions, Intravenous; Male; Renin | 1991 |
Oral administration of DuP 753, a specific angiotensin II receptor antagonist, to normal male volunteers. Inhibition of pressor response to exogenous angiotensin I and II.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Blood Pressure; Drug Evaluation; Heart Rate; Humans; Imidazoles; Losartan; Male; Renin-Angiotensin System; Tetrazoles | 1991 |
Effect of the circulating renin-angiotensin system on prolactin release in humans.
Topics: Adenoma; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Circadian Rhythm; Enalapril; Humans; Hypertension; Prolactin; Renin; Renin-Angiotensin System; Thyrotropin-Releasing Hormone | 1990 |
Determinants of angiotensin II generation during converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Male; Peptidyl-Dipeptidase A; Renin | 1990 |
Chronic treatment of hypertensive patients with converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Coronary Circulation; Enalapril; Heart Rate; Humans; Hypertension; Lipids; Oligopeptides; Peptidyl-Dipeptidase A; Potassium; Rats; Rats, Inbred SHR; Renin; Sodium; Teprotide | 1986 |
Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Double-Blind Method; Drug Administration Schedule; Heart Rate; Humans; Kinetics; Male; Pyridazines; Renin | 1987 |
Need for plasma angiotensin measurements to investigate converting-enzyme inhibition in humans.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Clinical Trials as Topic; Enalapril; Humans | 1989 |
The assessment of ACE activity in man following angiotensin I challenges: a comparison of cilazapril, captopril and enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Cilazapril; Dose-Response Relationship, Drug; Enalapril; Humans; Peptidyl-Dipeptidase A; Pyridazines; Time Factors; Vascular Resistance | 1989 |
Severe hypotension with bradycardia during renin inhibition with H142 in sodium deplete man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Bradycardia; Dose-Response Relationship, Drug; Epinephrine; Hemodynamics; Humans; Hypotension; Infusions, Intravenous; Male; Norepinephrine; Randomized Controlled Trials as Topic; Renin; Sodium | 1989 |
Interactions between cilazapril and propranolol in man; plasma drug concentrations, hormone and enzyme responses, haemodynamics, agonist dose-effect curves and baroreceptor reflex.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Heart Rate; Hemodynamics; Humans; Isoproterenol; Male; Norepinephrine; Pressoreceptors; Propranolol; Pyridazines; Renin; Renin-Angiotensin System; Time Factors | 1988 |
Converting enzyme inhibition in mild and moderate essential hypertension. I. Acute effects on blood pressure, the renin-angiotensin system and blood bradykinin after a single dose of captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Captopril; Clinical Trials as Topic; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 1985 |
Effect of dietary sodium on angiotensin-converting enzyme (ACE) inhibition and the acute hypotensive effect of enalapril (MK-421) in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Clinical Trials as Topic; Diet, Sodium-Restricted; Dipeptides; Double-Blind Method; Enalapril; Enalaprilat; Female; Humans; Hypertension; Male; Middle Aged; Peptidyl-Dipeptidase A; Random Allocation; Renin; Sodium | 1984 |
Effects of tibalosine, a new alpha-adrenoceptor antagonist, in essential hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin I; Angiotensin II; Blood Glucose; Blood Pressure Determination; Clinical Trials as Topic; Creatinine; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Male; Metabolic Clearance Rate; Middle Aged; Posture; Propanolamines; Renin; Sodium | 1983 |
The renin-angiotensin system during converting enzyme inhibition with captopril in patients with severe treatment-resistant hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Blood Pressure; Captopril; Drug Resistance; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Proline; Propranolol; Renin; Renin-Angiotensin System | 1984 |
Comparison of angiotensin-converting enzyme inhibition with angiotensin II receptor antagonism in the human forearm.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Bradykinin; Double-Blind Method; Drug Interactions; Enalapril; Forearm; Heart Rate; Humans; Imidazoles; Losartan; Male; Regional Blood Flow; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 1993 |
Value of different clinical and biochemical correlates to assess angiotensin converting enzyme inhibition.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Humans; Injections, Intravenous; Male; Reproducibility of Results; Tablets; Thiazepines | 1994 |
Comparison of the angiotensin II antagonist UP269-6 with the angiotensin converting enzyme inhibitor enalapril in normotensive volunteers challenged with angiotensin I.
Topics: Administration, Oral; Adult; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Humans; Male; Plethysmography; Pyrimidines; Renin; Tetrazoles | 1995 |
Additive effects of combined angiotensin-converting enzyme inhibition and angiotensin II antagonism on blood pressure and renin release in sodium-depleted normotensives.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Synergism; Heart Rate; Humans; Hydrocortisone; Male; Peptidyl-Dipeptidase A; Reference Values; Renin; Sodium | 1995 |
Inhibition of angiotensin-converting enzyme with libenzapril in normotensive males.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Pressure; Drug Administration Schedule; Humans; Infusions, Intravenous; Male | 1994 |
Angiotensin II formation by an alternative pathway during exercise in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Benzamidines; Blood Pressure; Bradykinin; Captopril; Cross-Over Studies; Double-Blind Method; Exercise; Guanidines; Heart Rate; Humans; Lactates; Lactic Acid; Male; Peptidyl-Dipeptidase A; Renin; Serine Proteinase Inhibitors | 1994 |
Blood pressure effects of acute intravenous renin or oral angiotensin converting enzyme inhibition in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Injections, Intravenous; Male; Middle Aged; Renin; Time Factors | 1994 |
Fetotoxicity of angiotensin-converting enzyme inhibition in primate pregnancy: a prospective, placebo-controlled study in baboons (Papio hamadryas).
Topics: Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Enalapril; Female; Fetal Death; Fetal Growth Retardation; Papio; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Outcome; Prospective Studies; Random Allocation; Renin | 1994 |
A comparison of spirapril and isradipine in patients with diabetic nephropathy and hypertension.
Topics: Adult; Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Double-Blind Method; Enalapril; Endothelium, Vascular; Female; Humans; Hypertension; Isradipine; Lipoproteins; Male; Middle Aged; Potassium; Sodium | 1993 |
Comparison of blood pressure and angiotensin responses to the renin inhibitor Ro 42-5892 and the angiotensin converting enzyme inhibitor enalapril in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Enalapril; Female; Hemodynamics; Humans; Hypertension; Imidazoles; Male; Middle Aged; Renin | 1993 |
N-acetylcysteine inhibits angiotensin converting enzyme in vivo.
Topics: Acetylcysteine; Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Female; Heart Rate; Humans; Isosorbide Dinitrate; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin | 1993 |
Differential effects of oral losartan and enalapril on local venous and systemic pressor responses to angiotensin I and II in healthy men.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Enalapril; Hand; Humans; Imidazoles; Losartan; Male; Reference Values; Renin; Tetrazoles; Vasoconstriction; Veins | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Epoprostenol; Female; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Time Factors | 1996 |
Interruption of prolonged ramipril treatment in hypertensive patients: effects on the renin-angiotensin system.
Topics: Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Peptidyl-Dipeptidase A; Potassium; Ramipril; Renin; Renin-Angiotensin System | 1996 |
Additive effects of losartan and enalapril on blood pressure and plasma active renin.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enalapril; Heart Rate; Humans; Hydrocortisone; Imidazoles; Losartan; Male; Peptidyl-Dipeptidase A; Renin; Tetrazoles; Time Factors | 1997 |
Further evidence that chronic perindopril treatment maintains neurohormonal suppression but does not lower blood pressure in chronic cardiac failure.
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiac Output, Low; Chronic Disease; Depression, Chemical; Female; Humans; Indoles; Kidney Function Tests; Male; Middle Aged; Perindopril | 1997 |
[AT1 angiotensin receptor inhibition as a new therapeutic possibility].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Female; Heart Failure; Humans; Hypertension; Losartan; Renin-Angiotensin System | 1997 |
Gender affects renal vasoconstrictor response to Ang I and Ang II.
Topics: Adult; Aldosterone; Analysis of Variance; Angiotensin I; Angiotensin II; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Male; Renal Circulation; Renin; Sex Characteristics; Single-Blind Method; Vasoconstriction | 1998 |
Endogenous angiotensin II contributes to basal peripheral vascular tone in sodium deplete but not sodium replete man.
Topics: Adult; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Vessels; Bradykinin; Diuretics; Dose-Response Relationship, Drug; Forearm; Furosemide; Humans; Losartan; Lower Body Negative Pressure; Male; Norepinephrine; Regional Blood Flow; Sodium; Sodium, Dietary; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Human vascular renin-angiotensin system and its functional changes in relation to different sodium intakes.
Topics: Adult; Angiotensin I; Angiotensin II; Double-Blind Method; Female; Forearm; Humans; Leg; Male; Renin-Angiotensin System; Sodium, Dietary | 1998 |
Effects of MDL 100,240, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase on the vasopressor response to exogenous angiotensin I and angiotensin II challenges in healthy volunteers.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Area Under Curve; Benzazepines; Blood Pressure; Double-Blind Method; Enzyme Inhibitors; Humans; Male; Neprilysin; Placebos; Pyridines; Reference Values | 1998 |
A radioreceptor assay for the analysis of AT1-receptor antagonists. Correlation with complementary LC data reveals a potential contribution of active metabolites.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Proteins; Chromatography, High Pressure Liquid; Double-Blind Method; Humans; Imidazoles; Losartan; Male; Placebos; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Reference Values; Sensitivity and Specificity; Tetrazoles | 1998 |
Pharmacokinetic-pharmacodynamic interactions of candesartan cilexetil and losartan.
Topics: Administration, Oral; Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Double-Blind Method; Humans; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles | 1999 |
Effect of angiotensin-(1-7) and bradykinin in patients with heart failure treated with an ACE inhibitor.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Cardiac Output, Low; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Humans; Male; Peptide Fragments | 1999 |
Nonadherence with angiotensin-converting enzyme inhibitor therapy: a comparison of different ways of measuring it in patients with chronic heart failure.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Chronic Disease; Diuretics; Drug Therapy, Combination; Echocardiography; Furosemide; Heart Failure; Humans; Lisinopril; Oligopeptides; Peptidyl-Dipeptidase A; Radionuclide Ventriculography; Treatment Outcome; Treatment Refusal | 1999 |
Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure.
Topics: Aged; Angiotensin I; Angiotensin II; Chronic Disease; Cross-Over Studies; Diuretics; Double-Blind Method; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Heart Failure; Humans; Male; Middle Aged; Nitric Oxide; omega-N-Methylarginine; Spironolactone; Vasodilation | 2000 |
The angiotensin-converting enzyme gene polymorphism and responses to angiotensins and bradykinin in the human forearm.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Bradykinin; Forearm; Genotype; Humans; Infusions, Intravenous; Male; Middle Aged; Nitroprusside; Peptidyl-Dipeptidase A; Plethysmography; Polymorphism, Genetic; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
Functional importance of angiotensin-converting enzyme-dependent in situ angiotensin II generation in the human forearm.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Brachial Artery; Enalaprilat; Endothelium, Vascular; Forearm; Humans; Losartan; Male; Middle Aged; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Regional Blood Flow; Vasoconstriction | 2000 |
Angiotensin II formation in human vasculature after chronic ACE inhibition: a prospective, randomized, placebo-controlled study. QUO VADIS Investigators.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiovascular Diseases; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Single-Blind Method | 2000 |
Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Dipeptides; Double-Blind Method; Female; Fishes; Humans; Hydrolysis; Hypertension; Male; Middle Aged; Muscles; Reference Values | 2000 |
Augmented responses of angiotensin I and II in patients with ischemic heart disease: relation to left ventricular function.
Topics: Aged; Angiotensin I; Angiotensin II; Exercise Test; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Pilot Projects; Renin-Angiotensin System; Stroke Volume; Sympathetic Nervous System; Ventricular Dysfunction, Left; Ventricular Function, Left | 2000 |
Nicardipine did not activate renin-angiotensin-aldosterone system during isoflurane or sevoflurane anesthesia.
Topics: Aged; Aldosterone; Anesthesia, Inhalation; Anesthetics, Inhalation; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Isoflurane; Male; Methyl Ethers; Middle Aged; Nicardipine; Renin; Renin-Angiotensin System; Sevoflurane | 2000 |
Cigarette smoking in men and vascular responsiveness.
Topics: Acetylcholine; Adolescent; Adult; Angiotensin I; Angiotensin II; Blood Flow Velocity; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Plethysmography; Receptors, Endothelin; Smoking; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2001 |
Vasoconstrictor effect of the angiotensin-converting enzyme-resistant, chymase-specific substrate [Pro(11)(D)-Ala(12)] angiotensin I in human dorsal hand veins: in vivo demonstration of non-ace production of angiotensin II in humans.
Topics: Administration, Oral; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chronic Disease; Chymases; Dose-Response Relationship, Drug; Double-Blind Method; Hand; Humans; Infusions, Intravenous; Irbesartan; Middle Aged; Peptidyl-Dipeptidase A; Reproducibility of Results; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction; Veins | 2001 |
Angiotensin(1-7) potentiates bradykinin-induced vasodilatation in man.
Topics: Adult; Angiotensin I; Angiotensin II; Bradykinin; Cross-Over Studies; Double-Blind Method; Drug Synergism; Enzyme Inhibitors; Humans; Male; omega-N-Methylarginine; Peptide Fragments; Reference Values; Vasoconstrictor Agents; Vasodilation | 2001 |
Long-term effects of olmesartan, an Ang II receptor antagonist, on blood pressure and the renin-angiotensin-aldosterone system in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Olmesartan Medoxomil; Pulse; Renin; Renin-Angiotensin System; Respiration Disorders; Tetrazoles; Time Factors | 2001 |
Angiotensin II suppression in humans by the orally active renin inhibitor Aliskiren (SPP100): comparison with enalapril.
Topics: Administration, Oral; Adult; Aldosterone; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Enalapril; Fumarates; Heart Rate; Humans; Male; Potassium; Renin; Renin-Angiotensin System; Sodium | 2002 |
Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Chronic Disease; Cross-Over Studies; Cross-Sectional Studies; Double-Blind Method; Female; Heart Failure; Humans; Lisinopril; Longitudinal Studies; Male; Middle Aged; Time Factors | 2002 |
Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Diet, Sodium-Restricted; Female; Genotype; Glomerular Filtration Rate; Humans; Kidney; Male; Peptidyl-Dipeptidase A; Renal Circulation; Vascular Resistance | 2002 |
Elevated plasma aldosterone levels despite complete inhibition of the vascular angiotensin-converting enzyme in chronic heart failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Chronic Disease; Enzyme Activation; Female; Heart Failure; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Radial Artery; Sodium, Dietary; Tonometry, Ocular; Treatment Outcome | 2002 |
Effects of truncated angiotensins in humans after double blockade of the renin system.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Chromium Radioisotopes; Edetic Acid; Humans; Male; Natriuresis; Peptide Fragments; Potassium; Renin; Renin-Angiotensin System; Sodium; Vasopressins | 2003 |
Effects of conjugated oestrogen and droloxifene on the renin-angiotensin system, blood pressure and renal blood flow in postmenopausal women.
Topics: Aged; Angiotensin I; Angiotensin II; Blood Pressure; Cross-Over Studies; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Linear Models; Middle Aged; Postmenopause; Renal Circulation; Renin-Angiotensin System; Selective Estrogen Receptor Modulators; Tamoxifen | 2004 |
Blockade of the angiotensin II type 1 receptor stabilizes atherosclerotic plaques in humans by inhibiting prostaglandin E2-dependent matrix metalloproteinase activity.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Collagen; Combined Modality Therapy; Cyclooxygenase 1; Cyclooxygenase 2; Depression, Chemical; Dinoprostone; Endarterectomy, Carotid; Enzyme Induction; Extracellular Matrix; Female; Gene Expression Regulation; Humans; Inflammation; Intramolecular Oxidoreductases; Irbesartan; Isoenzymes; Macrophages; Male; Matrix Metalloproteinase Inhibitors; Membrane Proteins; Prostaglandin-E Synthases; Prostaglandin-Endoperoxide Synthases; Protease Inhibitors; Rupture, Spontaneous; Tetrazoles | 2004 |
17ss oestradiol does not attenuate the response to angiotensin I and II during long term therapy in postmenopausal women.
Topics: Angiotensin I; Angiotensin II; Blood Flow Velocity; Double-Blind Method; Estradiol; Estrogen Replacement Therapy; Female; Forearm; Humans; Middle Aged; Postmenopause; Vasoconstrictor Agents | 2004 |
Statin therapy increases vascular sensitivity to angiotensin II in hypercholesterolaemic patients.
Topics: Angiotensin I; Angiotensin II; Brachial Artery; Cholesterol; Cross-Over Studies; Double-Blind Method; Female; Forearm; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Norepinephrine; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption.
Topics: Administration, Oral; Adolescent; Adult; Aldosterone; Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Drug Synergism; Feedback, Physiological; Fumarates; Humans; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2004 |
Losartan increases bradykinin levels in hypertensive humans.
Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes | 2005 |
Sodium status and angiotensin-converting enzyme inhibition: effects on plasma angiotensin-(1-7) in healthy man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Diet, Sodium-Restricted; Enalapril; Humans; Male; Peptide Fragments; Placebos; Renin-Angiotensin System; Sodium, Dietary | 2005 |
Angiotensin II plays an important role in maintaining blood pressure in postmenopausal women receiving hormone replacement therapy.
Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Therapy, Combination; Epinephrine; Estrogens; Female; Heart Rate; Hormone Replacement Therapy; Humans; Middle Aged; Norepinephrine; Peptidyl-Dipeptidase A; Postmenopause; Renin; Tetrazoles; Treatment Outcome | 2005 |
Different effects of transdermal and oral hormone replacement therapy on the renin-angiotensin system, plasma bradykinin level, and blood pressure of normotensive postmenopausal women.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Estradiol; Estrogen Replacement Therapy; Female; Humans; Middle Aged; Postmenopause; Renin-Angiotensin System | 2006 |
Gradual reactivation of vascular angiotensin I to angiotensin II conversion during chronic ACE inhibitor therapy in patients with diabetes mellitus.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Hypertension; Kinetics; Lisinopril; Male; Middle Aged | 2007 |
Does blockade of the renin angiotensin system affect sympathetic and blood pressure responses to amlodipine in young hypertensive patients?
Topics: Adult; Amlodipine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Norepinephrine; Quinapril; Renin; Sympathetic Nervous System; Tetrahydroisoquinolines | 2007 |
Development of hypertension and effects of benazepril hydrochloride in a canine remnant kidney model of chronic renal failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Dog Diseases; Dogs; Female; Hypertension; Kidney Failure, Chronic; Male; Renin | 2008 |
Renal and hormonal responses to direct renin inhibition with aliskiren in healthy humans.
Topics: Administration, Oral; Adult; Amides; Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Diet; Dose-Response Relationship, Drug; Female; Fumarates; Glomerular Filtration Rate; Humans; Male; Middle Aged; Natriuresis; Predictive Value of Tests; Reference Values; Renal Circulation; Renal Plasma Flow; Renin; Sodium; Sodium, Dietary; Vasodilation | 2008 |
A new-generation N/L-type calcium channel blocker leads to less activation of the renin-angiotensin system compared with conventional L type calcium channel blocker.
Topics: Aged; Albuminuria; Aldosterone; Amlodipine; Angiotensin I; Angiotensin II; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle Aged; Renin; Renin-Angiotensin System | 2010 |
Safety, tolerability, pharmacokinetics, and pharmacodynamics of fimasartan following single and repeated oral administration in the fasted and fed states in healthy subjects.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Food-Drug Interactions; Half-Life; Humans; Intestinal Absorption; Male; Metabolic Clearance Rate; Middle Aged; Pyrimidines; Renin; Tetrazoles; Young Adult | 2011 |
Imidapril provides a protective effect on pulmonary hypertension induced by low ambient temperature in broiler chickens.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterial Pressure; Chickens; Cold Temperature; Hypertension, Pulmonary; Imidazolidines; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Poultry Diseases; Proliferating Cell Nuclear Antigen; Pulmonary Artery | 2014 |
Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Double-Blind Method; Female; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2013 |
Imidapril inhibits right ventricular remodeling induced by low ambient temperature in broiler chickens.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animal Husbandry; Animals; Chickens; Cold Temperature; Gene Expression Regulation; Heart Ventricles; Housing, Animal; Imidazolidines; Peptide Fragments; Peptidyl-Dipeptidase A; Ventricular Remodeling | 2013 |
Angiotensin-(1-7)-induced renal vasodilation in hypertensive humans is attenuated by low sodium intake and angiotensin II co-infusion.
Topics: Angiotensin I; Angiotensin II; Diet, Sodium-Restricted; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Vasodilation | 2013 |
Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements.
Topics: Adult; Allostasis; Angiotensin I; Angiotensin II; Biomarkers; C-Reactive Protein; Electroencephalography; Epinephrine; Heart Rate; Humans; Interleukin-1; Interleukin-10; Interleukin-6; Male; Middle Aged; Military Personnel; Monitoring, Physiologic; Norepinephrine; North Carolina; Peptide Fragments; Pilot Projects; Self Report; Stress Disorders, Post-Traumatic; Vasopressins; Veterans | 2017 |
1874 other study(ies) available for angiotensin ii and angiotensin i
| Article | Year |
|---|---|
New mass spectrometric assay for angiotensin-converting enzyme 2 activity.
Topics: Angiotensin I; Angiotensin II; Animals; Humans; Isoenzymes; Kidney; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Angiotensin metabolism in renal proximal tubules, urine, and serum of sheep: evidence for ACE2-dependent processing of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blotting, Western; Female; In Vitro Techniques; Iodine Radioisotopes; Kidney Tubules, Proximal; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Sheep | 2007 |
Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Down-Regulation; Enalapril; Hemodynamics; Male; Myocardial Infarction; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Ventricular Dysfunction; Ventricular Function, Left | 2006 |
Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; CD13 Antigens; Cells, Cultured; Glutamyl Aminopeptidase; Humans; Mesangial Cells; Mice; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Podocytes; Protease Inhibitors; Renin; Renin-Angiotensin System; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2007 |
Angiotensin processing is partially carried out by carboxypeptidases in the rat mesenteric arterial bed perfusate.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Carboxypeptidases; In Vitro Techniques; Kinetics; Mesenteric Arteries; Peptide Fragments; Perfusion; Phenanthrolines; Protease Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Wistar; Substrate Specificity | 2008 |
Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Cardiomegaly; Cell Enlargement; Cells, Cultured; Enalapril; Humans; Hypertrophy, Left Ventricular; In Vitro Techniques; Insulin-Like Growth Factor I; Male; Myocardial Infarction; Myocytes, Cardiac; Norepinephrine; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Ventricular Function, Left | 2010 |
Angiotensin-(1-9), the product of angiotensin I conversion in platelets, enhances arterial thrombosis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Blood Platelets; Humans; Losartan; Male; Partial Thromboplastin Time; Peptide Fragments; Platelet Aggregation; Prothrombin Time; Rats; Rats, Wistar; Thrombosis | 2010 |
Carboxypeptidases A1 and A2 from the perfusate of rat mesenteric arterial bed differentially process angiotensin peptides.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Base Sequence; Carboxypeptidases A; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Kinetics; Mesenteric Arteries; Molecular Sequence Data; Organ Specificity; Peptide Fragments; Perfusion; Rats | 2012 |
Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Humans; Hydrolysis; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins | 2012 |
The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Benzopyrans; Down-Regulation; Drug Therapy, Combination; Ethanolamines; Female; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Nebivolol; Peptide Fragments; Renin-Angiotensin System; Vasodilator Agents | 2013 |
Stimulation of ANP by angiotensin-(1-9) via the angiotensin type 2 receptor.
Topics: Algorithms; Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Atrial Natriuretic Factor; Cyclic GMP; Heart Atria; Hemodynamics; Imidazoles; Male; Nitric Oxide; Oncogene Protein v-akt; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction; Stimulation, Chemical | 2013 |
Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cardiovascular Diseases; Disease Models, Animal; Echocardiography; Endothelium, Vascular; Heart Ventricles; Hemodynamics; Hypertension; Imidazoles; Male; Oxidative Stress; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley | 2014 |
Functional Local Renin-Angiotensin System in Human and Rat Periodontal Tissue.
Topics: Adult; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Gingiva; Humans; Inflammation; Male; Middle Aged; Peptide Fragments; Periodontitis; Periodontium; Rats, Wistar; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Young Adult | 2015 |
"Big big renin*. Enzymatic and partial physical characterization of a new high molecular weight renin from normal human kidney.
Topics: Angiotensin I; Angiotensin II; Chromatography, Gel; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Isoelectric Point; Kidney; Kinetics; Molecular Weight; Renin | 1977 |
An international collaborative study of renin assay: establishment of the international reference preparation of human renin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Biological Assay; Humans; Hydrogen-Ion Concentration; Radioimmunoassay; Reference Values; Renin | 1975 |
Converting-enzyme activity and pressor responses to angiotensin I and II in the rat awake and during anesthesia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Ethers; Halothane; Hyponatremia; In Vitro Techniques; Ketamine; Male; Peptidyl-Dipeptidase A; Rabbits; Rats; Renin | 1979 |
Feedback regulation of nephron filtration rate during pharmacologic interference with the renin-angiotensin and adrenergic systems in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Catecholamines; Glomerular Filtration Rate; Kidney Glomerulus; Kidney Tubules; Male; Nephrons; Rats; Renin; Teprotide | 1979 |
Change of the activities of angiotensins I and II on the vascular smooth muscle by crude kallikrein.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aorta; Kallikreins; Kinetics; Perfusion; Rabbits; Structure-Activity Relationship | 1977 |
Cryoactivation of renin in human plasma [proceedings].
Topics: Angiotensin I; Angiotensin II; Enzyme Activation; Freezing; Humans; Renin | 1978 |
Hyponatraemic hypertensive syndrome with renal-artery occlusion corrected by captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Arginine Vasopressin; Blood Pressure; Captopril; Female; Humans; Hypertension, Malignant; Hyponatremia; Middle Aged; Potassium; Proline; Renal Artery Obstruction; Renin; Syndrome | 1979 |
Enzyme immunoassay of angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; beta-Galactosidase; Dogs; Immunoenzyme Techniques; Radioimmunoassay; Renin; Vasopressins | 1979 |
Influence of angiotensins (I, II, & III), bradykinin and arachidonic acid on renomedullary PGE production in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Arachidonic Acids; Bradykinin; Cyclooxygenase Inhibitors; Indomethacin; Kidney Medulla; Male; Meclofenamic Acid; Prostaglandins E; Rabbits; Rats | 1979 |
Renin activity and concentrations of angiotensin I and II in amniotic fluid of normal and Rh-sensitized pregnancies.
Topics: Adult; Amniotic Fluid; Angiotensin I; Angiotensin II; Angiotensins; Betamethasone; Blood Group Incompatibility; Female; Gestational Age; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications, Hematologic; Radioimmunoassay; Renin; Rh-Hr Blood-Group System; Urine | 1979 |
Central cardiovascular effects of SQ 14,225, an angiotensin-converting enzyme inhibitor in chloralose-anesthetized cats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain; Cats; Female; Heart Rate; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Male; Proline; Time Factors | 1977 |
Inhibition of angiotensin converting enzyme by SQ 14,225 in conscious rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Drug Synergism; Kidney; Male; Proline; Rabbits; Substrate Specificity | 1977 |
Angiotensin receptors.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Animals; Aorta; Female; In Vitro Techniques; Kinetics; Nephrectomy; Receptors, Angiotensin; Receptors, Cell Surface; Uterus | 1978 |
Role of cyclic AMP and angiotensin III in the response of toad skin to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Bufo arenarum; Cyclic AMP; Electrophysiology; In Vitro Techniques; Permeability; Skin; Water | 1978 |
Effects of SQ 14,225, an orally active inhibitor of angiotensin-converting enzyme on blood pressure, heart rate and plasma renin activity of conscious normotensive dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs; Heart Rate; Proline; Renin | 1978 |
Zinc deficiency and lung converting enzyme activity in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Lung; Peptidyl-Dipeptidase A; Rats; Zinc | 1979 |
Direct evidence for the presence of a different converting enzyme in the hamster cheek pouch.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cheek; Cricetinae; Female; Oligopeptides; Peptidyl-Dipeptidase A; Vasoconstriction | 1979 |
Effects of continuous converting enzyme blockade on renovascular hypertension in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Hypertension, Renal; Hypertension, Renovascular; Male; Peptidyl-Dipeptidase A; Rats; Time Factors | 1979 |
Characterization of receptors for angiotensin in the rat vas deferens.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Aorta; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Vas Deferens | 1979 |
Evidence for an endogenous brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Cathepsins; Cattle; Dogs; Humans; Peptidyl-Dipeptidase A; Rabbits; Radioimmunoassay; Rats; Receptors, Angiotensin; Renin | 1979 |
[Pathogenesis of arterial hypertension with special reference to the kinins and prostaglandins].
Topics: Angiotensin I; Angiotensin II; Cyclic AMP; Humans; Hypertension; Kallidin; Kallikreins; Kinins; Pressoreceptors; Prostaglandins; Renin | 1979 |
Inhibitors of the renin-angiotensin system in experimental hypertension, with a note on the measurement of angiotensin I, II and III during infusion of converting-enzyme inhibitor.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Dogs; Female; Hypertension, Renal; Male; Oligopeptides; Proline; Rats; Saralasin; Teprotide | 1979 |
Effect of an angiotensin converting enzyme inhibitor (SQ 14,225) on beta-adrenergic and angiotensin-induced thirsts.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Drinking; Female; Isoproterenol; Proline; Rats; Thirst | 1979 |
Interaction of [125I]LH-RH and other oligopeptides with plasma membranes of rat anterior pituitaries.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Membrane; Female; Gonadotropin-Releasing Hormone; Membrane Proteins; Oxytocin; Pituitary Gland, Anterior; Rats; Receptors, Cell Surface; Temperature | 1979 |
Active and inactive renin in normal human plasma. Comparison between acid activation and cryoactivation.
Topics: Acids; Adult; Aldosterone; Angiotensin I; Angiotensin II; Cold Temperature; Diet; Enzyme Activation; Humans; Peptidyl-Dipeptidase A; Renin | 1979 |
Structural features of angiotensin II which are important for biologic activity.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Guinea Pigs; Molecular Conformation; Rabbits; Rats; Structure-Activity Relationship | 1979 |
Effects of an orally active converting-enzyme inhibitor, SQ 14225, on pressor responses to angiotensin administered into the brain ventricles of spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cerebral Ventricles; Enzyme Inhibitors; Hypertension; Male; Pressoreceptors; Proline; Rats | 1979 |
Evidence for the conversion of angiotensin I to angiotensin II by the coronary microcirculation.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Coronary Vessels; Cricetinae; Female; Heart Transplantation; Microcirculation; Myocardial Contraction; Saralasin; Transplantation, Homologous; Vasoconstriction | 1979 |
Intrarenal role of renin-angiotensin system in the regulation of renal hemodynamics.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Hemodynamics; Kidney; Renin | 1979 |
Captopril in hypertension with renal artery stenosis and in intractable hypertension; acute and chronic changes in circulating concentrations of renin, angiotensins I and II and aldosterone, and in body composition.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Potassium; Proline; Renal Artery Obstruction; Renin; Sodium | 1979 |
Blood pressure effects of endogenous brain angiotensin in rats are increased by inhibition of prostaglandin biosynthesis.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Indomethacin; Male; Nephrectomy; Rats; Renin | 1979 |
Synthesis and pharmacology of a prohormone angiotensin antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Saralasin; Uterine Contraction | 1979 |
Effects of cigarette smoke on the metabolism of vasoactive hormones in rat isolated lungs.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Hormones; In Vitro Techniques; Indomethacin; Lung; Male; Methysergide; Prostaglandins E; Rats; Smoking; Time Factors | 1979 |
Intrarenal vascular effects of [des-Asp1] angiotensin I and angiotensin III in the dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Dogs; Dose-Response Relationship, Drug; Female; Injections, Intra-Arterial; Kidney; Male; Receptors, Angiotensin; Regional Blood Flow; Teprotide | 1979 |
Potentiating mechanism of bradykinin action on smooth muscle by sulfhydryl compounds.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Animals; Bradykinin; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Time Factors | 1979 |
Mechanism for renal tubular handling of angiotensin.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; In Vitro Techniques; Kidney Tubules, Proximal; Leucine; Microvilli; Rabbits; Tritium | 1979 |
[Effect of propyl-(D,L)-alanine peptidylhydrolase on vasoactive peptides].
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Catalysis; Cattle; Peptide Fragments; Peptides; Pituitary Gland; Teprotide | 1979 |
Physiological effects of angiotensin. Introduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Humans; Renin | 1979 |
The brain renin-angiotensin system: a critical analysis.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Brain; Brain Chemistry; Cathepsins; Dogs; Renin | 1979 |
Intrarenal effects of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Dogs; Glomerular Filtration Rate; Hemodynamics; Kidney; Rats; Renin; Saralasin; Teprotide | 1979 |
Formation of angiotensin III from [des-Asp1]angiotensin I in the mesentric vasculature.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Dogs; Dose-Response Relationship, Drug; Female; Male; Mesenteric Arteries; Mesentery; Regional Blood Flow; Teprotide; Vasoconstrictor Agents | 1979 |
Evidence for the local occurrence of angiotensin II in rat kidney and its modulation by dietary sodium intake and converting enzyme blockade.
Topics: Angiotensin I; Angiotensin II; Animals; Diet; Diet, Sodium-Restricted; Freezing; Kidney; Male; Oligopeptides; Perfusion; Rats; Renin; Sheep; Sodium Chloride; Teprotide | 1979 |
The kidney in health and disease: XII. Hormones and the kidney.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Bartter Syndrome; Dihydroxycholecalciferols; Hormones; Humans; Hydrocortisone; Insulin; Kidney; Parathyroid Hormone; Potassium; Prostaglandins; Renin | 1979 |
[Physiology of the renin-angiotensin system].
Topics: Aldosterone; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Chromaffin System; Humans; Kidney; Muscle Contraction; Renin; Sodium | 1979 |
Inotropic and vasoactive effects of the naturally occurring angiotensins in isolated cat cardiac muscle and coronary arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cats; Coronary Vessels; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Myocardial Contraction | 1979 |
Angiotensins I and II in renal vein blood.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensins; Humans; Hypertension; Middle Aged; Renal Artery; Renal Artery Obstruction; Renal Veins; Renin | 1979 |
Hypertension, hyperkalaemia and abnormalities of the renin-angiotensin system in diabetes mellitus.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hyperkalemia; Hypertension; Middle Aged; Potassium; Renin | 1979 |
Central hypertensive actions of angiotensin I, II and III in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Injections, Intraventricular; Male; Rats | 1979 |
Role of endogenous prostaglandins on the conversion of angiotensin I to angiotensin II in the pulmonary circulation.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aspirin; Biotransformation; Blood Pressure; Female; Lung; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Prostaglandins E; Rats; Teprotide | 1979 |
Cross-tachyphylaxis of the pressor response to angiotensins in conscious rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Dose-Response Relationship, Drug; Norepinephrine; Rabbits; Tachyphylaxis; Vasomotor System | 1979 |
Metabolism of angiotensin and bradykinin in rat isolated lungs during the oestrous cycle [proceedings].
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Estrus; Female; In Vitro Techniques; Lung; Metabolism; Pregnancy; Rats | 1979 |
Blockade of pressor responses to angiotensins I and II and noradrenaline using phentolamine, propranolol and hexamethonium in conscious rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Autonomic Nervous System; Blood Pressure; Hexamethonium Compounds; Norepinephrine; Phentolamine; Propranolol; Rabbits | 1979 |
Actions of alpha-, beta- and ganglion-blockade on the pressor responses to angiotensins I and II in the conscious rabbit [proceedings].
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Isoproterenol; Norepinephrine; Phentolamine; Propranolol; Rabbits | 1978 |
Effect of angiotensins and epinephrine on vascular resistance of isolated dogfish gut.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Digestive System; Dogfish; Epinephrine; Female; In Vitro Techniques; Regional Blood Flow; Sharks; Vascular Resistance | 1978 |
Differential actions of anaesthetic agents on the pressor potency of angiotensins I and II in the rabbit [proceedings].
Topics: Anesthetics; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Pentobarbital; Rabbits; Thiopental; Urethane | 1978 |
Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Drug Interactions; Female; Hypertension; Nephrectomy; Oligopeptides; Rats; Saralasin; Sodium Chloride; Teprotide | 1978 |
Comparison of angiotensin I and angiotensin II antibody trapping methods for determination of plasma renin concentration and activity.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Antigen-Antibody Reactions; Humans; Radioimmunoassay; Renin | 1978 |
In vitro and in vivo inhibition of renin by fatty acids.
Topics: Angiotensin I; Angiotensin II; Animals; Arachidonic Acids; Blood Pressure; Fatty Acids, Nonesterified; Kinetics; Linoleic Acids; Male; Rats; Renin; Substrate Specificity | 1978 |
Lack of specific inhibition of angiotensin II in eels by angiotensin antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Eels; Female; Norepinephrine; Phentolamine; Rats; Receptors, Angiotensin; Saralasin; Species Specificity; Teprotide; Vasomotor System | 1978 |
Role of renal prostaglandins in circulatory homeostasis.
Topics: Adrenal Cortex; Aldosterone; Angiotensin I; Angiotensin II; Animals; Catecholamines; Dogs; Hemodynamics; Homeostasis; Humans; Kallikreins; Kidney; Kinins; Prostaglandins E; Prostaglandins F; Rabbits; Regional Blood Flow; Renin; Sodium Chloride | 1978 |
Measurement of plasma renin activity as a valid estimation of plasma angiotensin status.
Topics: Angiotensin I; Angiotensin II; Humans; Radioimmunoassay; Renin | 1978 |
Contractile responses of isolated dog mesenteric arteries to angiotensin I, II and III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Bradykinin; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth; Saralasin; Vasoconstrictor Agents | 1978 |
Nomenclature of the renin-angiotensin system. Report of the Nomenclature Committee of the International Society of Hypertension (ISH) on the occasion of the 5th meeting of the ISH in Paris, June 12--14, 1978.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Renin; Terminology as Topic | 1978 |
In vivo enzyme activity of purified human brain renin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood Pressure; Brain; Cathepsins; Humans; Injections, Intraventricular; Male; Rats; Renin | 1978 |
Pharmacokinetic and pharmacodynamic studies of infusions with [Sar 1, Val5, Ala8] angiotensin II (saralasin).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chlorthalidone; Diet, Sodium-Restricted; Female; Humans; Hypertension, Renal; Kinetics; Male; Rats; Renin; Saralasin | 1978 |
In vivo and in vitro conversion of des-1-Asp angiotensin I to angiotensin III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Dogs; Female; Hydrolysis; In Vitro Techniques; Male; Plasma | 1978 |
Intrarenal renin and angiotensins in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Animals; Blood Urea Nitrogen; Dehydration; Female; Glomerular Filtration Rate; Glycerol; Radioimmunoassay; Rats; Renin | 1978 |
The distribution of immunoreactive angiotensins I and II extracted from rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Antigen-Antibody Reactions; Brain Chemistry; Female; Hypothalamus; Nephrectomy; Pituitary Gland; Radioimmunoassay; Rats; Thalamus | 1978 |
Radioimmunoassay of unprocessed sheep blood extracts to follow angiotensin metabolism.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Antibodies; Cross Reactions; Kidney; Radioimmunoassay; Sheep; Tissue Distribution | 1977 |
[Interaction of renin-angiotensin system with prostaglandins for the mediation of pulmonary vasoconstrictive response to alveolar hypoxia (author's transl)].
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Hypoxia; Lung; Prostaglandins; Prostaglandins E; Prostaglandins F; Pulmonary Alveoli; Rats; Vasomotor System | 1977 |
Effects of cigarette smoking on the function of metabolizing arachidonic acid and angiotensin I in the isolated perfused rat lungs.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Arachidonic Acid; In Vitro Techniques; Lung; Male; Rats; Rats, Wistar; Thromboxane B2; Tobacco Smoke Pollution | 1992 |
[The changes in plasma renin angiotensin and arginine vasopressin in pulmonary hypertension rats].
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Hypertension, Pulmonary; Hypoxia; Rats; Rats, Wistar; Renin; Renin-Angiotensin System | 1992 |
A peptide family being re-united: the angiotensins coming in from the cold.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Blood Pressure; Homeostasis; Kidney; Renin-Angiotensin System | 1992 |
Production of angiotensin-(1-7) by human vascular endothelium.
Topics: Angiotensin I; Angiotensin II; Animals; Enalaprilat; Endothelium, Vascular; Humans; Iodine Radioisotopes; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Umbilical Veins | 1992 |
Dietary Na and ACE inhibition effects on renal tissue angiotensin I and II and ACE activity in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chromatography, High Pressure Liquid; Diet; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium | 1992 |
Effect of captopril on the release of the components of the renin-angiotensin system into plasma and lymph.
Topics: Angiotensin I; Angiotensin II; Animals; Capillary Resistance; Captopril; Dehydration; Denervation; Dogs; Glomerular Filtration Rate; Kidney Transplantation; Lymph; Peptidyl-Dipeptidase A; Renal Circulation; Renin; Renin-Angiotensin System; Sodium Chloride; Transplantation, Heterotopic | 1992 |
Increased vascular formation of angiotensin II in one-kidney, one clip hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blood Vessels; Captopril; Enalapril; Hypertension, Renovascular; In Vitro Techniques; Male; Mesenteric Arteries; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Reference Values; Saralasin | 1992 |
In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalaprilat; Endopeptidases; Hypertension; Male; Neprilysin; Osmolar Concentration; Peptide Fragments; Prolyl Oligopeptidases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Serine Endopeptidases; Time Factors | 1992 |
Relation between inhibition of renal angiotensin II production and hemodynamic effect of captopril in anesthetized rabbit.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rabbits; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles | 1992 |
Measurement of converting enzyme activity by antibody-trapping of generated angiotensin II. Comparison with two other methods.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Antibodies, Monoclonal; Antibody Specificity; Enalapril; Humans; Methods; Peptidyl-Dipeptidase A; Radioimmunoassay; Reference Values | 1992 |
Circulating angiotensin II levels under repeated administration of lisinopril in normal subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dipeptides; Humans; Lisinopril; Peptidyl-Dipeptidase A; Renin; Substance Withdrawal Syndrome | 1992 |
Comparison of angiotensin-converting enzyme inhibitors in the rat in perfused hindlimbs and in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dipeptides; Dose-Response Relationship, Drug; Hemodynamics; Hindlimb; Lisinopril; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred SHR; Vascular Resistance | 1992 |
[Effects of angiotensin peptides on airway epithelial ion transport and its modulation by angiotensin converting enzyme].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cells, Cultured; Chlorine; Dogs; Dose-Response Relationship, Drug; Enalaprilat; Epithelial Cells; Epithelium; Ion Transport; Peptidyl-Dipeptidase A; Trachea | 1992 |
[Cholinergic suppression of the angiotensin I-converting reaction].
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; Heart Rate; Male; Rats; Receptors, Cholinergic; Renin-Angiotensin System | 1992 |
Angiotensin and angiotensin converting enzyme tissue levels in two-kidney, one clip hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Hypertension, Renovascular; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Reference Values; Renin | 1992 |
Effects of angiotensin peptides on cholinergic neurotransmission in rabbit tracheal smooth muscle.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Parasympathetic Nervous System; Physostigmine; Rabbits; Synaptic Transmission; Trachea | 1992 |
Cardiac angiotensin converting enzyme and diastolic function of the heart.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Diastole; Enalaprilat; Heart; In Vitro Techniques; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Reference Values; RNA, Messenger; Ventricular Function, Left | 1992 |
Tonin-like activity present in the human submandibular gland.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Humans; Molecular Sequence Data; Molecular Weight; Peptidyl-Dipeptidase A; Submandibular Gland; Substrate Specificity | 1992 |
Electrophoresis, autoradiography and electroblotting of peptides: T4 gene 60 hopping.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Autoradiography; Bacteriophage T4; DNA Topoisomerases, Type I; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data; Protein Biosynthesis | 1992 |
Local generation and action of angiotensin II in dog iris sphincter muscle.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Dogs; Dose-Response Relationship, Drug; Female; Iris; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A | 1992 |
Angiotensin converting activity assessed in vivo is increased in hereditary hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Hypertension; Lung; Male; Nitroprusside; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1992 |
Angiotensin-(1-7) is a potent antidiuretic peptide in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Diuresis; Dose-Response Relationship, Drug; Male; Peptide Fragments; Rats; Rats, Wistar; Water-Electrolyte Balance | 1992 |
Differential actions of angiotensin II and angiotensin-(1-7) on transmitter release.
Topics: Angiotensin I; Angiotensin II; Animals; Brain Chemistry; Male; Medulla Oblongata; Neurotransmitter Agents; Peptide Fragments; Potassium; Rats; Rats, Inbred Strains | 1992 |
Impact of enalapril therapy on in vitro coronary artery responsiveness in pacing-induced heart failure.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; Dogs; Enalapril; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Male; Vasoconstriction | 1992 |
Detection of angiotensin I and II in cultured rat cardiac myocytes and fibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Biological Assay; Cells, Cultured; Chromatography, High Pressure Liquid; Fibroblasts; Fluorescent Antibody Technique; Myocardium; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Staining and Labeling | 1992 |
Effects of the neutral endopeptidase inhibitor, SQ 28,603, on regional haemodynamic responses to atrial natriuretic peptide or proendothelin-1 [1-38] in conscious rats.
Topics: Alanine; Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Endothelin-1; Endothelins; Heart Rate; Injections, Intravenous; Male; Neprilysin; Protein Precursors; Rats | 1992 |
Concomitant release of renin, angiotensin I, and angiotensin II during superfusion of human juxtaglomerular cell tumor.
Topics: Adult; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Dopamine; Female; Humans; Juxtaglomerular Apparatus; Kidney Neoplasms; Microscopy, Electron; Octreotide; Perfusion; Renin | 1992 |
Angiotensin II--derived peptides devoid of phenylalanine in position 8 have full psychotropic activity of the parent hormone.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Avoidance Learning; Behavior, Animal; Injections, Intraventricular; Male; Motor Activity; Peptide Fragments; Phenylalanine; Psychotropic Drugs; Rats; Rats, Wistar; Stereotyped Behavior; Time Factors | 1992 |
Antihypertensive and hormonal activity of MK 954 in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Hormones; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Tetrazoles | 1992 |
Colocalization and release of angiotensin and renin in renal cortical cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Enalapril; Hemolytic Plaque Technique; Immunohistochemistry; Kidney Cortex; Male; Microscopy, Electron; Microscopy, Immunoelectron; Rats; Rats, Inbred WKY; Renin; Tissue Distribution | 1992 |
Hemodynamic effects of central angiotensin I, II, and III in conscious rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain; Dose-Response Relationship, Drug; Enalapril; Female; Heart Rate; Hemodynamics; Injections, Intraventricular; Male; Rabbits | 1992 |
Urinary excretion of angiotensin I, II, arginine vasopressin and oxytocin in patients with anaphylactoid reactions.
Topics: Adult; Anaphylaxis; Angiotensin I; Angiotensin II; Antipyrine; Arginine Vasopressin; Aspirin; Benzoates; Benzoic Acid; Female; Humans; Male; Middle Aged; Oxytocin; Vitamin B 12 | 1992 |
Effects, release and disposal of endothelin-1 in conscious dogs.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Blood Pressure; Dogs; Enalapril; Endothelins; Female; Heart Rate; Potassium; Radioimmunoassay; Sodium; Urea | 1992 |
[125I]EXP985: a highly potent and specific nonpeptide radioligand antagonist for the AT1 angiotensin receptor.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Iodine Radioisotopes; Ligands; Losartan; Microsomes; Muscle, Smooth, Vascular; Rats; Tetrazoles | 1992 |
Inhibition of the haemodynamic effects of angiotensin II in conscious rats by AT2-receptor antagonists given after the AT1-receptor antagonist, EXP 3174.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Pyridines; Rats; Regional Blood Flow; Tetrazoles | 1992 |
Vasoconstrictive effects of angiotensin I and II in cat femoral arteries. Role of endothelium.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cats; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Saralasin; Vasoconstriction | 1992 |
Lack of correlation between the acute haemodynamic response to intravenous captopril and plasma concentrations of angiotensin II in patients with chronic cardiac failure.
Topics: Aged; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Cardiac Output; Cardiomyopathy, Dilated; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Vascular Resistance | 1992 |
Metabolism of angiotensin I by different tissues in the intact animal.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Heart Ventricles; Hemodynamics; Injections; Iodine Radioisotopes; Peptides; Swine; Tissue Distribution | 1992 |
Production of angiotensins I and II at tissue sites in intact pigs.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Renin; Swine; Tissue Distribution | 1992 |
Contractions induced by angiotensin I, angiotensin II and bradykinin in isolated smooth muscle from the human detrusor.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Mesenteric Arteries; Middle Aged; Muscle, Smooth; Muscle, Smooth, Vascular; Potassium Chloride; Rabbits | 1992 |
Presence of angiotensin peptides in human urine.
Topics: Adult; Anaphylaxis; Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Radioimmunoassay | 1992 |
Angiotensin-related intakes of water and NaCl in Fischer 344 and Sprague-Dawley rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Appetite; Blood Pressure; Cerebral Ventricles; Drinking Behavior; Heart Rate; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Renin; Sodium, Dietary; Species Specificity | 1992 |
AT1 angiotensin receptors mobilize intracellular calcium in a subclone of NG108-15 neuroblastoma cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Imidazoles; Intracellular Membranes; Losartan; Neuroblastoma; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1992 |
Captopril inhibits angiotensin I-induced coronary flow reduction in isolated rat heart but has no effect on contractility or energy metabolism.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Animals; Captopril; Coronary Circulation; Coronary Disease; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
Mapping of angiotensin II receptor subtype heterogeneity in rat brain.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Brain; Brain Mapping; Dithiothreitol; Imidazoles; Iodine Radioisotopes; Losartan; Male; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1992 |
Local renin-angiotensin system in human adrenals and aldosteronomas.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Male; Middle Aged; Renin; Renin-Angiotensin System; RNA, Messenger | 1992 |
Losartan, a specific angiotensin II receptor antagonist, increases angiotensin I and angiotensin II release from isolated rat hind legs: evidence for locally regulated renin-angiotensin system in vascular tissue.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Vessels; Hindlimb; Imidazoles; Losartan; Male; Muscle, Smooth, Vascular; Nephrectomy; Perfusion; Rats; Renin-Angiotensin System; Tetrazoles; Time Factors | 1992 |
Increased angiotensin-(1-7) in hypophysial-portal plasma of conscious sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Chromatography, High Pressure Liquid; Endopeptidases; Gonadotropin-Releasing Hormone; Median Eminence; Peptide Fragments; Peptides; Pituitary Gland; Portal System; Prolyl Oligopeptidases; Radioimmunoassay; Renin; Serine Endopeptidases; Sheep | 1992 |
Comparative effects of Des Leu Angiotensin I and Angiotensin II on AVP secretion from the hypothalamoneurohypophysis and pituitary of the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Hypothalamus; In Vitro Techniques; Male; Pituitary Gland, Posterior; Potassium Chloride; Rats; Rats, Inbred Strains | 1992 |
The pressor response to exogenous angiotensin I and its blockade by angiotensin II analogues in the American alligator.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Alligators and Crocodiles; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Injections, Intravenous; Norepinephrine; Saralasin | 1992 |
Electrophysiological responses of angiotensin peptides on the rat isolated nodose ganglion.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Electrophysiology; In Vitro Techniques; Male; Nodose Ganglion; Peptide Fragments; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Serotonin | 1992 |
Differential baroreceptor reflex modulation by centrally infused angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Brain; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex | 1992 |
Distribution and metabolism of angiotensin I and II in the blood vessel wall.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Blood Vessels; In Vitro Techniques; Male; Rabbits; Time Factors; Tissue Distribution | 1992 |
Effects of the new angiotensin-I-converting enzyme inhibitor imidapril on the responses of isolated vascular preparations to various agonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Bradykinin; Dinoprost; Dogs; Endothelium, Vascular; Female; Imidazoles; Imidazolidines; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Rabbits; Serotonin | 1992 |
Prolyl endopeptidase purified from granulomatous inflammation in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Female; Granuloma; Hydrolysis; Immunohistochemistry; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Prolyl Oligopeptidases; Serine Endopeptidases; Substrate Specificity | 1992 |
Effects of angiotensin II and angiotensin converting enzyme inhibitors on contractile and growth responses in isolated carotid arteries of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carotid Arteries; DNA; Enalapril; In Vitro Techniques; Lisinopril; Male; Rats; Rats, Inbred WKY; Vasoconstriction | 1991 |
Identification of serine proteinases with tonin-like activity in the rat submandibular and prostate glands.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kallikreins; Male; Peptidyl-Dipeptidase A; Prostate; Rats; Rats, Inbred Strains; Serine Endopeptidases; Serine Proteinase Inhibitors; Submandibular Gland | 1991 |
Angiotensin-II receptor subtypes in fetal tissue of the rat: autoradiography, guanine nucleotide sensitivity, and association with phosphoinositide hydrolysis.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Fetus; Gestational Age; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Imidazoles; Losartan; Oligopeptides; Phosphatidylinositols; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1991 |
Measurement of angiotensin converting enzyme induction and inhibition using quantitative in vitro autoradiography: tissue selective induction after chronic lisinopril treatment.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Autoradiography; Edetic Acid; Enalapril; Enzyme Induction; Kidney; Lisinopril; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Testis | 1991 |
Evidence that prolyl endopeptidase participates in the processing of brain angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Dogs; Endopeptidases; Hypothalamus; In Vitro Techniques; Iodine Radioisotopes; Male; Peptide Fragments; Prolyl Oligopeptidases; Radioimmunoassay; Renin-Angiotensin System; Serine Endopeptidases | 1991 |
Studies on the renin-angiotensin system in primary monolayer cell cultures of the rat epididymis.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Epididymis; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1991 |
Angiotensin-II activation of cAMP and corticosterone production in bovine adrenocortical cells: effects of nonpeptide angiotensin-II antagonists.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cattle; Corticosterone; Cyclic AMP; Imidazoles; Losartan; Pyridines; Saralasin; Tetrazoles | 1991 |
Beta-adrenergic-induced local angiotensin generation in the rabbit hind limb is dependent on the kidney.
Topics: Adrenergic beta-Agonists; Angiotensin I; Angiotensin II; Animals; Blood Urea Nitrogen; Hematocrit; Hemodynamics; Hindlimb; Isoproterenol; Kidney; Male; Rabbits; Renin | 1991 |
Direct effects in vivo of angiotensins I and II on the canine sinus node.
Topics: Adrenergic beta-Antagonists; Anesthesia; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Heart Rate; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Saralasin; Sinoatrial Node; Vagotomy | 1991 |
Substrate-dependent angiotensin II formation in the peripheral circulation.
Topics: Angiotensin I; Angiotensin II; Animals; Aprotinin; Captopril; Chromatography, High Pressure Liquid; Chymotrypsin; Male; Oligopeptides; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Substrate Specificity | 1990 |
Conversion of angiotensin I to angiotensin II in dog isolated renal artery: role of two different angiotensin II-generating enzymes.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dinoprost; Dogs; Endothelium, Vascular; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Oligopeptides; Peptidyl-Dipeptidase A; Renal Artery; Serine Endopeptidases; Thiazolidines; Tranylcypromine | 1990 |
Angiotensin-converting activity of tissue kallikrein.
Topics: Angiotensin I; Angiotensin II; Animals; Aprotinin; Captopril; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kallikreins; Rats | 1990 |
Control of renal function by intrarenal angiotensin II in the dog.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; Peptidyl-Dipeptidase A | 1990 |
Contribution of splanchnic and peripheral vascular tissues to the disposal of angiotensin-II and to regional conversion rates of angiotensin-I: a pilot study in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biotransformation; Blood Pressure; Enalaprilat; Femur; Heart Rate; Humans; Indocyanine Green; Injections, Intra-Arterial; Liver Circulation; Male; Regional Blood Flow; Splanchnic Circulation | 1991 |
Angiotensin II receptors in Xenopus oocytes.
Topics: Action Potentials; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Calcium; Chlorides; Female; Ion Channels; Molecular Sequence Data; Oocytes; Ovarian Follicle; Potassium; Receptors, Angiotensin; Xenopus laevis | 1991 |
Specific, high-affinity binding sites for angiotensin II on Mycoplasma hyorhinis.
Topics: Angiotensin I; Angiotensin II; Animals; Aprotinin; Bacitracin; Binding, Competitive; Cell Line; Dithiothreitol; Humans; Kinetics; Mycoplasma; Radioligand Assay; Receptors, Angiotensin; Species Specificity | 1991 |
In vivo evaluation of the antagonist activity of angiotensin I analogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Biphenyl Compounds; Captopril; Imidazoles; Losartan; Lung; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Tetrazoles | 1992 |
Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Epoprostenol; Imidazoles; Losartan; Oligopeptides; Prostaglandins; Pyridines; Receptors, Angiotensin; Tetrazoles | 1992 |
Possible role of the vascular renin-angiotensin system in hypertension and vascular hypertrophy.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Hypertension, Renovascular; Hypertrophy; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; RNA, Messenger; Veins | 1992 |
Endothelin stimulated by angiotensin II augments contractility of spontaneously hypertensive rat resistance arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Endothelins; Endothelium, Vascular; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Vascular Resistance; Vasoconstriction | 1992 |
Effects of angiotensin subtype 1 and subtype 2 receptor antagonists in normotensive versus hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Infusions, Intravenous; Losartan; Mesentery; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1991 |
Role of angiotensin on paracrine prolactin release in the pituitary gland and its possible effects on ovarian function.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Enalapril; Estradiol; Female; Gonadotropin-Releasing Hormone; In Vitro Techniques; Luteinizing Hormone; Male; Microscopy, Phase-Contrast; Ovary; Pituitary Gland; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Saralasin; Swine; Time Factors | 1991 |
Renin- and angiotensin-like immunoactivities in human ovarian follicular fluid in in vitro fertilization.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Buserelin; Chorionic Gonadotropin; Embryo Transfer; Estradiol; Female; Fertilization in Vitro; Follicular Fluid; Humans; Menotropins; Oogenesis; Ovulation Induction; Pregnancy; Radioimmunoassay; Renin; Renin-Angiotensin System | 1991 |
Receptors for angiotensins I and II: their relevance to renal haemodynamics, blood pressure control and hind-limb blood flow.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Models, Biological; Receptors, Angiotensin; Regional Blood Flow; Renal Circulation; Sheep | 1991 |
Angiotensin I conversion and coronary constriction by angiotensin II in ischemic and hypoxic isolated rat hearts.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Heart; Hypoxia; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Saralasin; Vasoconstriction | 1991 |
Quantitation of circulating angiotensin II using commercial immunoassays.
Topics: Angiotensin I; Angiotensin II; Humans; Radioimmunoassay; Reagent Kits, Diagnostic | 1991 |
Angiotensin I and II disappear completely from circulating blood within 48 hours after binephrectomy: improved measurement of angiotensins in rat plasma.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Chromatography, High Pressure Liquid; Diet, Sodium-Restricted; Hypertension, Renal; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin; Time Factors | 1991 |
Regional production of angiotensins I and II: contribution of vascular kidney-derived renin.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Female; Furosemide; Head; Kidney; Lung; Muscles; Myocardium; Renin; Skin; Swine | 1991 |
Ro 42-5892 is a potent orally active renin inhibitor in primates.
Topics: Administration, Oral; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Callitrichinae; Cattle; Cilazapril; Dogs; Dose-Response Relationship, Drug; Heart Rate; Humans; Imidazoles; Immunoradiometric Assay; Kidney; Minoxidil; Nephrectomy; Pyridazines; Rats; Regression Analysis; Renin; Saimiri; Sodium Chloride; Stereoisomerism | 1991 |
Local generation of angiotensin II as a mechanism of aldosterone secretion in rat adrenal capsules.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Enalapril; Female; In Vitro Techniques; Lisinopril; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1991 |
Angiotensin-(1-7). A member of circulating angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Dogs; Enalaprilat; Heart Rate; Male; Nephrectomy; Peptide Fragments; Peptides; Radioimmunoassay; Renin | 1991 |
Effect of endothelin on angiotensin converting enzyme activity in cultured pulmonary artery endothelial cells.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Cattle; Cells, Cultured; Endothelins; Endothelium, Vascular; In Vitro Techniques; Peptidyl-Dipeptidase A; Pulmonary Artery; Type C Phospholipases | 1991 |
Angiotensin II generation in the rat vena cava: stimulation of local synthesis by beta-adrenoceptor activation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Female; Guinea Pigs; Heart Atria; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin-Angiotensin System; Saralasin; Trachea; Tritium; Vena Cava, Superior | 1991 |
Characterization of angiotensin peptides in plasma of anephric man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Chromatography, High Pressure Liquid; Enzyme Precursors; Female; Humans; Kidney; Male; Middle Aged; Nephrectomy; Radioimmunoassay; Renin; Renin-Angiotensin System | 1991 |
Potassium-stimulated angiotensin release from superfused adrenal capsules and enzymatically dispersed cells of the zona glomerulosa.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Female; Periodicity; Potassium; Radioimmunoassay; Rats; Rats, Inbred Strains; Zona Glomerulosa | 1991 |
Renin increases human amnion cell prostaglandin E2 biosynthesis.
Topics: Amnion; Angiotensin I; Angiotensin II; Cells, Cultured; Cesarean Section; Dinoprostone; Female; Humans; Kinetics; Placenta; Pregnancy; Renin | 1991 |
Human astrocytes contain two distinct angiotensin receptor subtypes.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Astrocytes; Astrocytoma; Calcium; Cell Line; Cytosol; Dinoprostone; Dose-Response Relationship, Drug; Epoprostenol; Humans; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Peptide Fragments; Prostaglandins F; Receptors, Angiotensin; Signal Transduction; Tumor Cells, Cultured | 1991 |
Response of urinary angiotensin to challenges of the renin-angiotensin system.
Topics: Adult; Angiotensin I; Angiotensin II; Captopril; Enalapril; Female; Furosemide; Humans; Immersion; Indomethacin; Male; Renin; Renin-Angiotensin System; Sodium, Dietary | 1991 |
Synthesis and biological activity of angiotensin II analogues containing a Val-His replacement, Val psi[CH(CONH2)NH]His.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Chemical Phenomena; Chemistry, Physical; Dipeptides; Guinea Pigs; Ileum; Molecular Sequence Data; Muscle Contraction; Oligopeptides; Peptide Fragments; Rabbits; Receptors, Angiotensin; Saralasin | 1991 |
Evidence in the sheep for an interaction between systemic angiotensin II and cerebral angiotensinergic mechanisms.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Captopril; Carotid Arteries; Drinking Behavior; Hydrocortisone; Injections, Intra-Arterial; Injections, Intraventricular; Sheep | 1991 |
Juxtaglomerular cells as a source of intrarenal angiotensin II production.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; In Vitro Techniques; Juxtaglomerular Apparatus; Perfusion; Rats; Rats, Inbred Strains; Renin | 1991 |
Prolonged angiotensin II antagonism in spontaneously hypertensive rats. Hemodynamic and biochemical consequences.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Benzazepines; Biphenyl Compounds; Blood Pressure; Body Weight; Dose-Response Relationship, Drug; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Nephrectomy; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Time Factors | 1991 |
Studies of the renin-angiotensin system in the wall of rat femoral resistance vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Enzyme Precursors; Femoral Artery; In Vitro Techniques; Indoles; Kallikreins; Male; Muscle, Smooth, Vascular; Norepinephrine; Oligopeptides; Perindopril; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Saralasin; Vascular Resistance | 1991 |
Changes in expression of angiotensin receptor subtypes in the rat aorta during development.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Autoradiography; Binding, Competitive; Female; Fetus; Gestational Age; Iodine Radioisotopes; Kinetics; Male; Muscle Development; Muscle, Smooth, Vascular; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1991 |
Effect of a nonpeptide angiotensin II receptor antagonist, DuP 753, on angiotensin-related water intake in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Ventricles; Drinking Behavior; Imidazoles; Injections, Intraventricular; Injections, Subcutaneous; Losartan; Male; Mice; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Reference Values; Tetrazoles; Time Factors | 1991 |
Interaction of bradykinin and angiotensin in the regulation of blood pressure in conscious rats.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Drug Interactions; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Saralasin | 1991 |
Angiotensin I and II. Some early observations made at the Cleveland Clinic Foundation and recent discoveries relative to angiotensin II formation in human heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Myocardium | 1991 |
Effects of central and intravascular angiotensin I and II on the choroid plexus.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Circulation; Blood Pressure; Carbon Dioxide; Cerebral Ventricles; Cerebrovascular Circulation; Choroid Plexus; Infusions, Parenteral; Oxygen; Partial Pressure; Rabbits; Renal Circulation | 1991 |
Role of angiotensin and sodium intake in cardiac noradrenaline release.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Electric Stimulation; Heart; Male; Myocardium; Norepinephrine; Perfusion; Rats; Rats, Inbred Strains; Sodium; Tritium | 1991 |
A comparison of lisinopril with enalapril by monitoring plasma angiotensin II levels in humans.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Enalapril; Humans; Lisinopril; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Time Factors | 1990 |
[The vascular renin-angiotensin system].
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Humans; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System | 1990 |
Angiotensin converting enzyme inhibitor potentiated the vasorelaxant response of atrial natriuretic peptide in toad aortic rings.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Bufo arenarum; Dose-Response Relationship, Drug; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Time Factors | 1990 |
Vascular production and regulation of angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin | 1991 |
Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glioma; Imidazoles; Losartan; Oligopeptides; Peptide Fragments; Prostaglandins; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1991 |
New developments in renin and hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cardiovascular System; Humans; Hypertension; Kidney; Renin; Renin-Angiotensin System | 1991 |
Neurophysiological responses to angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Brain; Electrophysiology; Female; Iontophoresis; Neurons; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred WKY; Vasopressins | 1991 |
Effect of exercise training on blood pressure in 70- to 79-yr-old men and women.
Topics: Aged; Angiotensin I; Angiotensin II; Blood Pressure; Body Composition; Cardiac Output; Epinephrine; Exercise; Female; Heart Rate; Humans; Male; Norepinephrine; Oxygen Consumption; Physical Education and Training; Stroke Volume | 1991 |
Amphibian myocardial angiotensin II receptors are distinct from mammalian AT1 and AT2 receptor subtypes.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Cell Membrane; Dithiothreitol; Kinetics; Myocardium; Oocytes; Receptors, Angiotensin; Saralasin; Xenopus laevis | 1991 |
Increased production of angiotensin II in the adrenal gland of stroke-prone spontaneously hypertensive rats with malignant hypertension.
Topics: Adrenal Glands; Aging; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hypertension; Hypertension, Malignant; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin | 1991 |
Effect of captopril on congestive heart failure.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Captopril; Epinephrine; Female; Half-Life; Heart Failure; Humans; Male; Metabolic Clearance Rate; Middle Aged; Norepinephrine; Renin | 1990 |
Antihypertensive mechanism of action of the novel angiotensin converting enzyme inhibitor benazepril. Effect on isolated vascular preparations.
Topics: Alprostadil; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Bradykinin; Dinoprost; Dinoprostone; Epoprostenol; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rabbits; Rats; Rats, Inbred Strains; Serotonin | 1990 |
Does endocardial endothelium mediate positive inotropic response to angiotensin I and angiotensin II?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cats; Cyclooxygenase Inhibitors; Endocardium; Endothelium; In Vitro Techniques; Microscopy, Electron; Microscopy, Electron, Scanning; Myocardial Contraction | 1990 |
Acute changes in osmolality and renin and respiratory control of arterial PCO2 and [H+].
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Dogs; Female; Hydrogen-Ion Concentration; Male; Osmolar Concentration; Partial Pressure; Plasma Volume; Renin; Renin-Angiotensin System; Respiratory Physiological Phenomena; Vasopressins; Ventilation-Perfusion Ratio; Water-Electrolyte Balance | 1990 |
The effect of angiotensin I and III on the arachidonate cascade of brain microvessels.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arachidonic Acid; Arachidonic Acids; Brain Chemistry; Male; Microcirculation; Rats; Rats, Inbred Strains | 1990 |
Central effects of angiotensins I and II in conscious streptozotocin-treated rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Consciousness; Drinking; Heart Rate; Injections, Intraventricular; Male; Pressoreceptors; Rats; Rats, Brattleboro; Rats, Inbred Strains; Reflex; Streptozocin; Vasopressins | 1990 |
Quantitative evidence of peripheral conversion of angiotensin within the human leg: effects of local angiotensin-I administration and angiotensin-converting enzyme inhibition on regional blood flow and angiotensin-II balance across the leg.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biotransformation; Blood Pressure; Cilazapril; Heart Rate; Humans; Indocyanine Green; Leg; Muscles; Pyridazines; Regional Blood Flow | 1990 |
Flight influence on the plasma level of renin-angiotensin-aldosterone system and atrial natriuretic peptide.
Topics: Adult; Aerospace Medicine; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Humans; Hypertension; Male; Radioimmunoassay; Renin-Angiotensin System | 1990 |
Effect of metoclopramide on angiotensins, aldosterone, and atrial peptide during hypoxia.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Humans; Hypoxia; Metoclopramide; Oxygen; Potassium; Reference Values; Renin-Angiotensin System; Sodium | 1990 |
Endothelial renin-angiotensin pathway. Adrenergic regulation of angiotensin secretion.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Atenolol; Captopril; Cattle; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media; Endothelium, Vascular; Isoproterenol; Phenylephrine; Propanolamines; Radioimmunoassay; Receptors, Adrenergic, beta; Renin-Angiotensin System | 1990 |
Angiotensin II-forming pathways in normal and failing human hearts.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Captopril; Cardiac Output, Low; Female; Glycine max; Heart; Heart Ventricles; Humans; Male; Middle Aged; Myocardium; Peptidyl-Dipeptidase A; Reference Values; Trypsin Inhibitors | 1990 |
Increased colonic mucosal angiotensin I and II concentrations in Crohn's colitis.
Topics: Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Colitis; Colitis, Ulcerative; Colon; Colonoscopy; Crohn Disease; Humans; Intestinal Mucosa; Peptidyl-Dipeptidase A; Sigmoidoscopy; Single-Blind Method | 1990 |
Characterization of angiotensin I-converting enzyme (ACE)-containing follicles in the rat ovary during the estrous cycle and effects of ACE inhibitor on ovulation.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Captopril; Cell Membrane; Chorionic Gonadotropin; Dipeptides; Estrus; Female; Follicle Stimulating Hormone; Granulosa Cells; Iodine Radioisotopes; Ovarian Follicle; Ovary; Ovulation; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1990 |
Mechanism of increased angiotensin-converting enzyme activity stimulated by platelet-activating factor.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Cattle; Cells, Cultured; Endothelium; Neomycin; Peptidyl-Dipeptidase A; Platelet Activating Factor; Pulmonary Artery; Type C Phospholipases | 1990 |
Simultaneous radioimmunoassay of six angiotensin peptides in arterial and venous plasma of man.
Topics: Adult; Angiotensin I; Angiotensin II; Arteries; Chromatography, High Pressure Liquid; Humans; Male; Middle Aged; Radioimmunoassay; Renin; Veins | 1990 |
Platelet-activating factor stimulates angiotensin converting enzyme activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cattle; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Peptidyl-Dipeptidase A; Platelet Activating Factor | 1990 |
The role of tissue renin-angiotensin systems in hypertension and effects of chronic converting-enzyme inhibition.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Captopril; Enalapril; Gene Expression Regulation; Heart; Hydralazine; Hypertension; Isoquinolines; Kidney; Lisinopril; Male; Quinapril; Rats; Rats, Inbred SHR; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrahydroisoquinolines | 1990 |
Inhibition of neurotransmission by angiotensin I and II in rabbit isolated ear artery.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Captopril; Ear; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Regional Blood Flow; Saralasin; Synaptic Transmission | 1990 |
Effect of angiotensins on electrogenic anion transport in monolayer cultures of rat epididymis.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Anions; Captopril; Cells, Cultured; Cyclic AMP; Electron Transport; Epididymis; Male; Peptidyl-Dipeptidase A; Rats | 1990 |
The role of angiotensin-converting enzyme in the rat epididymis.
Topics: Angiotensin I; Angiotensin II; Animals; Body Fluids; Captopril; Epididymis; Fertility; Male; Orchiectomy; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1990 |
Bradykinin-induced contractions of canine prostate and bladder: effect of angiotensin-converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dogs; Enalaprilat; Female; Male; Muscle Contraction; Muscle, Smooth; Peptidyl-Dipeptidase A; Prostate; Urinary Bladder | 1990 |
Renin and angiotensin converting enzyme concentrations in the fetal and neonatal guinea-pig.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Female; Fetal Blood; Fetus; Gestational Age; Guinea Pigs; Lung; Male; Peptidyl-Dipeptidase A; Pregnancy; Propranolol; Renin | 1990 |
Angiotensin II-producing proteases from granulomatous tissue reaction in mice infected with Schistosoma mansoni.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Carboxypeptidases; Carboxypeptidases A; Chromatography, High Pressure Liquid; Granuloma; Hydrolases; Hydrolysis; Kinetics; Liver Diseases, Parasitic; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Peptidyl-Dipeptidase A; Schistosomiasis mansoni; Substrate Specificity | 1990 |
Pertussis toxin attenuates angiotensin II but not beta-adrenoceptor facilitation of noradrenaline release from rat kidney cortex.
Topics: Angiotensin I; Angiotensin II; Animals; Electric Stimulation; GTP-Binding Proteins; In Vitro Techniques; Isoproterenol; Kidney Cortex; Male; Norepinephrine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Virulence Factors, Bordetella | 1990 |
Effect of atrial natriuretic factor on angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Endothelium, Vascular; In Vitro Techniques; Peptide Fragments; Peptidyl-Dipeptidase A | 1990 |
Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Cattle; Cells, Cultured; Enalapril; Endothelins; Endothelium, Vascular; Nifedipine; Peptidyl-Dipeptidase A; Pulmonary Artery; Stimulation, Chemical | 1990 |
Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation.
Topics: Angiotensin I; Angiotensin II; Animals; Blotting, Northern; Cardiomyopathy, Hypertrophic; Coronary Circulation; Gene Expression; Hemodynamics; Male; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; RNA, Messenger; Vascular Resistance | 1990 |
Intracellular formation and release of angiotensins from juxtaglomerular cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Cytoplasmic Granules; Juxtaglomerular Apparatus; Microscopy, Electron; Peptidyl-Dipeptidase A; Rats; Renin | 1990 |
Angiotensins and the failing heart. Enhanced positive inotropic response to angiotensin I in cardiomyopathic hamster heart in the presence of captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Captopril; Cardiac Output, Low; Cardiomyopathies; Cricetinae; Drug Synergism; Heart; Male; Mesocricetus; Myocardial Contraction; Myocardium; Receptors, Angiotensin | 1990 |
Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Disease Models, Animal; Enzyme Precursors; Gene Expression; Hypertension; Kidney; Mice; Mice, Inbred DBA; Rats; Renin; Submandibular Gland; Transfection | 1990 |
Synthesis and pharmacological screening of new angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Availability; Blood Pressure; Bradykinin; Captopril; Chemical Phenomena; Chemistry; Enalapril; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Inbred Strains | 1990 |
Metabolism of tetradecapeptide, angiotensinogen and angiotensin I and II by isolated perfused rat hindlimbs.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Cattle; Hindlimb; Kidney; Nephrectomy; Pepstatins; Perfusion; Rats; Renin; Vasoconstrictor Agents | 1990 |
Vasopressor and depressor effects of native angiotensins and inhibition of these effects in the Japanese quail.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cardiovascular Physiological Phenomena; Cardiovascular System; Coturnix; Eels; Heart Rate; Humans; Kinetics; Male; Molecular Sequence Data; Quail; Species Specificity | 1990 |
Components of the angiotensin system cause release of a neutrophil chemoattractant from cultured bovine and human endothelial cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Endothelium, Vascular; Humans; In Vitro Techniques; Interleukin-8; Neutrophils; Pulmonary Artery; Renin-Angiotensin System; Saralasin; Umbilical Veins | 1990 |
The paracrine role of angiotensin in gonadotrophin-releasing hormone-stimulated prolactin release in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Estradiol; Estradiol Congeners; Luteinizing Hormone; Male; Pituitary Gland, Anterior; Pituitary Hormone-Releasing Hormones; Prolactin; Rats; Rats, Inbred Strains | 1990 |
Local formation of angiotensin II in the rat aorta: effect of endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Thoracic; Endothelium, Vascular; In Vitro Techniques; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Rats, Inbred Strains; Renin | 1990 |
In vivo generation and elimination of angiotensin in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Lung; Male; Rats; Rats, Inbred Strains; Renin | 1990 |
Accelerated synthesis and release of angiotensin II in the rat brain during electroacupuncture tolerance.
Topics: Acupuncture Analgesia; Angiotensin I; Angiotensin II; Animals; Brain; Electroacupuncture; Rats; Renin | 1990 |
Cardiac angiotensinogen and its local activation in the isolated perfused beating heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Dexamethasone; Female; Heart; In Vitro Techniques; Myocardium; Perfusion; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1990 |
[Local angiotensin in the myocardium of aging rats].
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Female; Myocardium; Rats; Rats, Inbred Strains | 1990 |
[A case report of high plasma renin activity in chronic pulmonary disease and the effect of angiotensin-II-analogue (1-sarcosine, 8-isoleucine-angiotensin-II)].
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Blood Pressure; Chronic Disease; Female; Humans; Lung Diseases; Male; Renin | 1990 |
Intrarenal de novo production of angiotensin I in subjects with renal artery stenosis.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Female; Humans; Kidney; Male; Middle Aged; Renal Artery Obstruction; Renin | 1990 |
Hymenoptera venom anaphylaxis: may decreased levels of angiotensin peptides play a role?
Topics: Adult; Anaphylaxis; Angiotensin I; Angiotensin II; Animals; Bee Venoms; Female; Humans; Male; Renin-Angiotensin System; Wasp Venoms | 1990 |
Re-evaluation of the plasma renin-angiotensin system in anephric patients.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Female; Humans; Male; Middle Aged; Nephrectomy; Radioimmunoassay; Renin; Renin-Angiotensin System | 1990 |
Identification of a highly specific chymase as the major angiotensin II-forming enzyme in the human heart.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Chromatography, Affinity; Chromatography, Gel; Chromatography, High Pressure Liquid; Chymases; Endopeptidases; Heart Ventricles; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Myocardium; Neuropeptides; Peptides; Protease Inhibitors; Sequence Homology, Nucleic Acid; Serine Endopeptidases; Substrate Specificity | 1990 |
Aortic smooth muscle cells are able to convert angiotensin I to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Cytosol; Endothelium, Vascular; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains | 1990 |
Modulation of noradrenaline release from rat cortical kidney slices: effects of angiotensin I and II.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Dioxanes; Electric Stimulation; Idazoxan; In Vitro Techniques; Kidney Cortex; Norepinephrine; Rats; Rats, Inbred Strains; Saralasin; Tetrodotoxin | 1990 |
Pharmacological evidence for the existence of a local renin-angiotensin system in porcine interlobar renal arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dinoprost; Enalapril; In Vitro Techniques; Indomethacin; Kallikreins; Kidney; Masoprocol; Muscle Relaxation; Renal Artery; Renin-Angiotensin System; Saralasin; Swine; Tranylcypromine | 1990 |
Biological activity of angiotensin-(1-7) heptapeptide in the hamster heart.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiac Output; Cardiomyopathies; Coronary Circulation; Cricetinae; Heart; Male; Mesocricetus; Peptide Fragments; Perfusion; Pressure; Reference Values | 1990 |
Actions of angiotensin peptides after partial denervation of the solitary tract nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Binding Sites; Denervation; Male; Medulla Oblongata; Peptide Fragments; Peptides; Rats; Rats, Inbred Strains; Sinus of Valsalva | 1990 |
Angiotensin binding sites in rabbit anterior uvea and human ciliary epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Binding, Competitive; Cells, Cultured; Ciliary Body; Data Interpretation, Statistical; Epithelium; Guanosine Triphosphate; Humans; Iris; Rabbits; Radioligand Assay; Receptors, Angiotensin; Regression Analysis; Uvea | 1990 |
Angiotensin II and angiotensin (1-7) excite neurons in the canine medulla in vitro.
Topics: Action Potentials; Angiotensin I; Angiotensin II; Animals; Dogs; In Vitro Techniques; Male; Medulla Oblongata; Peptide Fragments; Vagus Nerve | 1990 |
Prostaglandin production in response to angiotensin-(1-7) in rabbit isolated vasa deferentia.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Male; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Prostaglandins E; Rabbits; Stimulation, Chemical; Vas Deferens | 1990 |
Dot immunobinding and immunoblotting of picogram and nanogram quantities of small peptides on activated nitrocellulose.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, Thin Layer; Collodion; Enkephalin, Leucine; Enkephalin, Methionine; HIV; Humans; Immunoblotting; Peptides; Rabbits | 1990 |
Comparison of the dipsogenic responsiveness of Long-Evans and Sprague-Dawley rats.
Topics: Angiotensin I; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drinking; Isoproterenol; Male; Natriuresis; Rats; Rats, Inbred Strains; Species Specificity; Thirst; Water-Electrolyte Balance | 1990 |
Metabolism and production of angiotensin I in different vascular beds in subjects with hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Male; Middle Aged; Renin; Tissue Distribution | 1990 |
In vivo comparison of renal and femoral vascular sensitivity and local angiotensin generation.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Femoral Artery; Femoral Vein; Hemodynamics; Male; Nephrectomy; Rabbits; Renal Circulation; Renin; Renin-Angiotensin System | 1990 |
Effect of chronic enalapril treatment on enzymes responsible for the catabolism of angiotensin I and formation of angiotensin II.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Enalapril; Kidney; Neprilysin; Oligopeptides; Peptide Fragments; Peptides; Rats; Rats, Inbred WKY; Thiorphan | 1990 |
Renin inhibitors: their use in understanding the role of angiotensin II as a pressor hormone.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Dogs; Humans; Male; Oligopeptides; Papio; Renin; Sodium | 1985 |
Epitope diversity of angiotensin II analysed with monoclonal antibodies.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Binding Sites, Antibody; Binding, Competitive; Cross Reactions; Epitopes; Mice; Mice, Inbred BALB C; Phenylalanine | 1986 |
Effects of single doses of the converting enzyme inhibitor cilazapril in normal volunteers.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Dose-Response Relationship, Drug; Heart Rate; Humans; Male; Pyridazines | 1987 |
Analysis of influence of extra- and intrarenally formed angiotensin II on renal blood flow.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Male; Rabbits; Regional Blood Flow; Renal Circulation | 1986 |
Local control of jejunal absorption by the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; In Vitro Techniques; Intestinal Absorption; Jejunum; Kidney; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Tissue Extracts | 1986 |
Vascular angiotensin conversion in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Forearm; Humans; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Pyrroles; Ramipril; Reference Values; Regional Blood Flow; Renin | 1986 |
Vascular angiotensin converting enzyme in the development of renal hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Blood Pressure; Hypertension, Renal; Peptidyl-Dipeptidase A; Rats | 1986 |
Contractile effects of tetradecapeptide renin substrate on rat femoral resistance vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aprotinin; Captopril; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Vascular Resistance | 1987 |
Formation of angiotensin II by tonin-inhibitor complex.
Topics: alpha-Macroglobulins; Angiotensin I; Angiotensin II; Animals; Half-Life; Hydrolysis; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred Strains | 1988 |
Alteration of fate of vasoactive autacoids in pulmonary circulation following monocrotaline-induced lung vascular injury in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Autacoids; Blood Pressure; Body Weight; Bradykinin; Dinoprostone; Injections, Subcutaneous; Lung; Lung Diseases; Male; Monocrotaline; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Substance P; Time Factors | 1988 |
Effects of perindopril on tissue angiotensin-converting enzyme activity demonstrated by quantitative in vitro autoradiography.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Autoradiography; Blood Pressure; Indoles; Kidney; Lung; Male; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred Strains; Testis; Time Factors | 1988 |
Urinary angiotensin excretion during sodium restriction and diuretics.
Topics: Adult; Angiotensin I; Angiotensin II; Chlorothiazide; Diet, Sodium-Restricted; Diuretics; Female; Furosemide; Humans; Male; Metabolic Clearance Rate; Posture; Renin | 1989 |
Angiotensin increases arachidonate metabolism in cultured anterior pituitary cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin I; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diglycerides; Female; Indomethacin; Kinetics; Masoprocol; Phospholipids; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Saralasin | 1989 |
Modulation of natriuresis by sympathetic nerves and angiotensin II in conscious dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carotid Arteries; Dogs; Glomerular Filtration Rate; Kidney; Natriuresis; Ramipril; Reference Values; Reflex; Renal Artery; Renin; Sympathetic Nervous System | 1989 |
Distribution of two distinct Ca2+-ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaffin cells.
Topics: Adrenal Medulla; Angiotensin I; Angiotensin II; Animals; Antibodies, Monoclonal; Benzofurans; Caffeine; Calcium; Calcium-Transporting ATPases; Cattle; Cells, Cultured; Fluorescent Antibody Technique; Fluorescent Dyes; Fura-2; Inositol 1,4,5-Trisphosphate; Isoenzymes; Methacholine Chloride; Methacholine Compounds; Molecular Weight | 1989 |
On the pathogenesis of arterial blood pressure elevation early in the course of diabetic nephropathy.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Atrial Natriuretic Factor; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Extracellular Space; Female; Glomerular Filtration Rate; Humans; Hypertension; Male; Middle Aged; Plasma Volume; Renin; Renin-Angiotensin System | 1989 |
Cardiac arrhythmias are ameliorated by local inhibition of angiotensin formation and bradykinin degradation with the converting-enzyme inhibitor ramipril.
Topics: Action Potentials; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Bradykinin; Bridged Bicyclo Compounds; Digoxin; Female; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Rabbits; Ramipril; Rats; Rats, Inbred Strains | 1989 |
Metabolism of angiotensin peptides by neuronal and glial cultures from rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Hypertension; Kinetics; Neuroglia; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1989 |
Angiotensinogen's role in ANG formation, renin release, and renal hemodynamics in isolated perfused kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Inbred Strains; Renal Circulation; Renin-Angiotensin System | 1989 |
Kinetic studies of the pharmacologic response to captopril in rats. I. Role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension, Renovascular; Infusions, Intravenous; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System; Sodium | 1989 |
Enalapril decreases angiotensin II receptors in subfornical organ of SHR.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Enalapril; Male; Neurosecretory Systems; Organ Specificity; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Reference Values; Renin; Renin-Angiotensin System; Species Specificity; Subfornical Organ | 1989 |
Effects of angiotensin blockade on the splanchnic circulation in normotensive humans.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardiac Output; Enalapril; Epinephrine; Female; Gravitation; Heart Rate; Hemodynamics; Humans; Male; Norepinephrine; Splanchnic Circulation | 1989 |
The renin-angiotensin system during pregnancy in chronically instrumented, conscious rats.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Drug Synergism; Enalaprilat; Female; Glomerular Filtration Rate; Hemodynamics; Norepinephrine; Postpartum Period; Pregnancy; Pregnancy, Animal; Rats; Renal Circulation; Renin; Renin-Angiotensin System; Vasoconstriction | 1989 |
[Biochemical and functional changes during immunization of rats with angiotensin II].
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Brain; Drinking Behavior; Immunization; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Serum Albumin, Bovine | 1989 |
Effect of atrial natriuretic factor on angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Cattle; Cells, Cultured; Endothelium, Vascular; Peptidyl-Dipeptidase A; Pulmonary Artery; Vasodilation | 1989 |
Local inhibition of converting enzyme and vascular responses to angiotensin and bradykinin in the human forearm.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Circulation; Bradykinin; Enalaprilat; Forearm; Humans; Injections, Intra-Arterial; Male; Vasodilation | 1989 |
Angiotensin II-producing enzyme III from acidified serum of nephrectomized dogs.
Topics: Adrenergic alpha-Antagonists; alpha 1-Antitrypsin; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cathepsin G; Cathepsins; Dogs; Enzyme Precursors; Epinephrine; Female; Male; Nephrectomy; Norepinephrine; Serine Endopeptidases; Serine Proteinase Inhibitors | 1989 |
Angiotensin II vascular receptors in fowl aorta: binding specificity and modulation by divalent cations and guanine nucleotides.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Calcium; Endothelium, Vascular; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; In Vitro Techniques; Magnesium; Manganese; Poultry; Receptors, Angiotensin | 1989 |
Estimation of regional metabolism and production of angiotensins in hypertensive subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Arteries; Blood; Humans; Hypertension; Infusions, Intravenous; Iodine Radioisotopes; Middle Aged; Veins | 1989 |
Plasma kinin levels in experimental hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Hypertension; Kinins; Male; Rats; Rats, Inbred Strains; Reference Values; Sodium, Dietary | 1989 |
S-nitrosocaptopril. II. Effects on vascular reactivity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cattle; Coronary Vessels; Drug Interactions; Femoral Artery; In Vitro Techniques; Methylene Blue; Saralasin; Vasodilator Agents | 1989 |
Tumor promoter 12-O-tetradecanoylphorbol 13-acetate inhibits mas/angiotensin receptor-stimulated inositol phosphate production and intracellular Ca2+ elevation in the 401L-C3 neuronal cell line.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Bradykinin; Calcium; Cell Line; Enzyme Activation; Hydrogen-Ion Concentration; Inositol Phosphates; Neoplasm Proteins; Neurons; Protein Kinase C; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Spectrometry, Fluorescence; Sugar Phosphates; Tetradecanoylphorbol Acetate; Transfection | 1989 |
Angiotensin converting enzyme inhibition and renin inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Humans; Oligopeptides; Renin | 1989 |
Does angiotensin regulate systemic conversion of prorenin to renin?
Topics: Angiotensin I; Angiotensin II; Animals; Enzyme Precursors; In Vitro Techniques; Kidney Cortex; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renin | 1989 |
Effects of renin inhibition in the conscious primate Macaca fascicularis.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Furosemide; Heart Rate; Macaca mulatta; Oligopeptides; Osmolar Concentration; Renin; Structure-Activity Relationship | 1989 |
Angiotensin formation in the isolated rat hindlimb.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Hindlimb; In Vitro Techniques; Male; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Vasoconstriction | 1989 |
Direct evidence for local generation and release of angiotensin II in human vascular tissue.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Captopril; Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Pregnancy; Umbilical Veins | 1989 |
Facilitation of noradrenaline release by isoprenaline in rat isolated atria does not involve angiotensin II formation.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cocaine; Electric Stimulation; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred Strains; Saralasin | 1989 |
Local generation of angiotensin II in the isolated rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta; In Vitro Techniques; Male; Muscle Contraction; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1989 |
Pressure-dependent contraction of rat juxtamedullary afferent arterioles.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Arterioles; Furosemide; Homeostasis; Kidney Glomerulus; Kidney Medulla; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nephrons; Norepinephrine; Perfusion; Pressure; Rats; Renal Circulation | 1989 |
Characterization of binding sites for the angiotensin II antagonist 125I-[Sarc1,Ile8]-angiotensin II on murine neuroblastoma N1E-115 cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cell Division; Cell Membrane; Guanylyl Imidodiphosphate; Kinetics; Mice; Neuroblastoma; Receptors, Angiotensin; Tumor Cells, Cultured | 1989 |
Cardiovascular effects of angiotensin-(1-7) injected into the dorsal medulla of rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Peptide Fragments; Rats; Rats, Inbred Strains | 1989 |
Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensins; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Hypothalamus; Immune Sera; Male; Peptide Fragments; Protein Processing, Post-Translational; Radioimmunoassay; Rats; Rats, Inbred Strains | 1989 |
Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery.
Topics: Angiotensin I; Angiotensin II; Animals; Cerebral Arteries; Dogs; Drug Interactions; Endothelium, Vascular; Female; In Vitro Techniques; Male; Vasoconstriction | 1989 |
Effect of a monoclonal antibody to angiotensin II on hemodynamic responses to noradrenergic stimulation in pithed rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies, Monoclonal; Decerebrate State; Electric Stimulation; Hemodynamics; Male; Norepinephrine; Rats; Rats, Inbred Strains; Spinal Cord; Sympathetic Nervous System; Vasopressins | 1989 |
Renin-angiotensin system in sepsis.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Epinephrine; Furosemide; Humans; Multiple Trauma; Peptidyl-Dipeptidase A; Pneumonia; Renin; Renin-Angiotensin System; Respiratory Distress Syndrome; Sepsis | 1987 |
Hypoxia-induced inhibition of converting enzyme activity: role in vascular regulation.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Hypoxia; Male; Peptidyl-Dipeptidase A; Phenylephrine; Pulmonary Artery; Rats; Rats, Inbred Strains | 1987 |
Stimulation by angiotensins I and II of ACTH release from goldfish pituitary cell columns.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenocorticotropic Hormone; Angiotensin I; Angiotensin II; Animals; Captopril; Cells, Cultured; Cyprinidae; Female; Goldfish; In Vitro Techniques; Male; Pituitary Gland, Anterior; Saralasin | 1987 |
Effects of angiotensin I converting enzyme (ACE) related substances upon the vascular prostacyclin generation.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Cells, Cultured; Endothelium, Vascular; Epoprostenol; Humans; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY | 1987 |
The ventrolateral medulla. A new site of action of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cats; Enalapril; Enalaprilat; Heart Rate; Medulla Oblongata; Receptors, Angiotensin; Renin-Angiotensin System | 1988 |
In vitro renin inhibition to prevent generation of angiotensins during determination of angiotensin I and II.
Topics: Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Enalapril; Humans; Oligopeptides; Radioimmunoassay; Renin | 1988 |
Suppression of angiotensin II release by prostaglandin synthesis inhibitors in hind legs.
Topics: Angiotensin I; Angiotensin II; Animals; Dose-Response Relationship, Drug; Hindlimb; Indomethacin; Isoproterenol; Male; Meclofenamic Acid; ortho-Aminobenzoates; Propranolol; Prostaglandins; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Renin-Angiotensin System | 1988 |
Altered angiotensin-converting enzyme in lung and extrapulmonary tissues of hypoxia-adapted rats.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Dipeptides; Enalapril; Hypoxia; Lisinopril; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 1988 |
Measurement of angiotensin-converting enzyme activity in intact human alveolar macrophages and effect of smoking.
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Culture Media; Humans; Macrophages; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Smoking | 1988 |
In vivo renal angiotensin converting enzyme activity decreases in glycerol-induced acute renal failure.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Animals; Glomerular Filtration Rate; Glycerol; Kidney; Male; Mercuric Chloride; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renal Circulation | 1988 |
[Direct cardiac effects of angiotensins I and II and 2 converting enzyme inhibitors (captopril and perindopril). Indirect demonstration of a converting enzyme in the rat heart].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Coronary Circulation; Coronary Disease; Heart; Heart Rate; Indoles; Male; Myocardium; Peptidyl-Dipeptidase A; Perindopril; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Saralasin | 1988 |
Facilitatory presynaptic angiotensin receptors on the sympathetic nerves of the human saphenous vein and pulmonary artery. Potential involvement in beta-adrenoceptor-mediated facilitation of noradrenaline release.
Topics: Adrenergic Fibers; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin III; Cocaine; Corticosterone; Desipramine; Electric Stimulation; Female; Humans; Male; Norepinephrine; Pulmonary Artery; Receptors, Adrenergic, beta; Receptors, Angiotensin; Saphenous Vein; Saralasin | 1988 |
Formation of angiotensin II and other angiotensin peptides from des-leu 10-angiotensin I in rat lung and kidney.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Kidney; Lung; Lysine Carboxypeptidase; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats; Rats, Inbred Strains | 1988 |
Comparison of the effects of the dipeptidyl peptidase inhibitors captopril, ramipril, and enalapril on water intake and sodium appetite of Sprague-Dawley rats.
Topics: Angiotensin I; Angiotensin II; Animals; Appetite; Brain; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Captopril; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Drinking; Enalapril; Ramipril; Rats; Rats, Inbred Strains; Renin; Sodium Chloride | 1988 |
Influence of angiotensin II (AII) and angiotensin I (AI) on renal renin synthesis and release.
Topics: Angiotensin I; Angiotensin II; Animals; Enalapril; Female; Kidney; Rats; Rats, Inbred Strains; Renin | 1988 |
Facilitation of noradrenaline release from sympathetic nerves in rat anococcygeus muscle by activation of prejunctional beta-adrenoceptors and angiotensin receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Desipramine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Muscles; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Angiotensin; Saralasin; Sympathetic Nervous System | 1988 |
Conversion of kinins and their antagonists into B1 receptor activators and blockers in isolated vessels.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Bradykinin; Captopril; Dogs; Endothelium; In Vitro Techniques; Kinins; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter | 1986 |
Difference in the potency of alpha 2-adrenoceptor agonists and antagonists between the pithed rabbit and rat.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Guanabenz; Male; Norepinephrine; Phenylephrine; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Sympathetic Nervous System | 1987 |
Characterization of neurohormonal changes following the production of the benign and malignant phases of two-kidney, two-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Captopril; Catecholamines; Disease Models, Animal; Dogs; Epinephrine; Hexamethonium; Hexamethonium Compounds; Hypertension, Malignant; Hypertension, Renovascular; Neuropeptides; Norepinephrine; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1987 |
Effect of locally generated angiotensin II on noradrenergic neuroeffector function in the rat isolated caudal artery.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arteries; Enalapril; Enalaprilat; Female; Male; Neurotransmitter Agents; Oligopeptides; Rats; Rats, Inbred Strains; Tail | 1987 |
Changes in the biological activity of autacoids during passage through the human perfused fetoplacental lobule.
Topics: Angiotensin I; Angiotensin II; Autacoids; Bradykinin; Dinoprost; Female; Humans; In Vitro Techniques; Perfusion; Placenta; Pregnancy; Prostaglandins F; Regional Blood Flow; Serotonin; Vascular Resistance | 1987 |
Angiotensin metabolism by cerebral microvascular aminopeptidase A.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Animals; Brain; Cerebrovascular Circulation; gamma-Glutamyltransferase; Glutamyl Aminopeptidase; Kinetics; Microcirculation; Substrate Specificity; Swine | 1988 |
Perturbation of intracellular calcium ion concentration in single rat granulosa cells by angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Cells, Cultured; Female; Granulosa Cells; Kinetics; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Intrarenal generation of angiotensin II evaluated by an electrophysiological technique.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Bridged Bicyclo Compounds; Captopril; Female; Hydronephrosis; Juxtaglomerular Apparatus; Kidney; Membrane Potentials; Mice; Ramipril; Renin | 1987 |
Influence of ramipril diacid on the peripheral vascular effects of angiotensin I.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Forearm; Humans; Middle Aged; Ramipril; Regional Blood Flow; Renin | 1987 |
[Effects of conversion enzyme inhibitors on the synthesis of angiotensin II by the isolated rat kidney].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bridged Bicyclo Compounds; Captopril; Kidney; Male; Ramipril; Rats; Rats, Inbred Strains | 1987 |
Measurement and characterization of angiotensin peptides in plasma.
Topics: Adult; Angiotensin I; Angiotensin II; Animals; Blood Specimen Collection; Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Female; Humans; Iodine Radioisotopes; Male; Nephrectomy; Radioimmunoassay; Ramipril; Rats; Reference Values | 1988 |
Purification and identification of endogenous anti-opioid substances from bovine brain.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Angiotensins; Animals; Biological Assay; Brain Chemistry; Cattle; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enkephalin, Methionine; Guinea Pigs; Ileum; Male; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid | 1985 |
Apparently high plasma angiotensin II levels in patients with essential hypertension treated by converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Dipeptides; Enalapril; Enzyme Inhibitors; Humans; Hypertension; Radioimmunoassay | 1985 |
[Acute and long-term effect of captopril in severe chronic heart failure].
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Captopril; Chronic Disease; Drug Evaluation; Female; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Peptidyl-Dipeptidase A; Proline; Time Factors | 1985 |
Cardiovascular effects of a renin inhibitor in relation to posture in nonhuman primates.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Blood Pressure; Humans; Hypotension, Orthostatic; Macaca fascicularis; Male; Oligopeptides; Posture; Reflex; Renin; Renin-Angiotensin System; Saralasin; Sodium | 1985 |
[Drugs that block the angiotensin converting enzyme].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Drug Administration Schedule; Enalapril; Humans; Hypertension; Kidney; Kidney Glomerulus | 1985 |
Captopril in the hepatorenal syndrome.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Female; Humans; Iodine Radioisotopes; Kidney Diseases; Liver Diseases; Male; Middle Aged; Radioimmunoassay; Renin; Sodium; Syndrome | 1985 |
Synthesis and pharmacology of the potent angiotensin-converting enzyme inhibitor N-[1(S)-(ethoxycarbonyl)-3-phenylpropyl]-(S)-alanyl-(S)-pyroglutamic acid.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chemical Phenomena; Chemistry; Diet, Sodium-Restricted; Dipeptides; Enalapril; Heart Rate; Hydrochlorothiazide; Hypertension; Hypertension, Renovascular; Male; Rats; Rats, Inbred SHR | 1985 |
Angiotensin peptides stimulate phosphoinositide breakdown and prolactin release in anterior pituitary cells in culture.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Cells, Cultured; Female; Inositol Phosphates; Kinetics; Phosphatidylinositols; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin | 1986 |
Pharmacokinetic studies on pharmacologic response of captopril in rats.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Kinetics; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Sodium | 1985 |
Haemodynamic and humoral effects of lower body negative pressure in normal, sodium-replete man during angiotensin-converting enzyme inhibition with captopril.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arginine Vasopressin; Captopril; Epinephrine; Hemodynamics; Humans; Lower Body Negative Pressure; Male; Norepinephrine; Renin; Renin-Angiotensin System; Sodium | 1986 |
Role of the endothelium on the facilitatory effects of angiotensin I and angiotensin II on noradrenergic transmission in the caudal artery of the rat.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Vessels; Electric Stimulation; Enalapril; Enalaprilat; Endothelium; Female; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Synaptic Transmission; Tail | 1986 |
Effects of locally formed angiotensin II on renal hemodynamics.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Peptidyl-Dipeptidase A; Renal Circulation | 1986 |
An improved method for measuring angiotensin I converting enzyme activity using a highly sensitive angiotensin II radioimmunoassay.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Cross Reactions; Edetic Acid; Enalapril; Leucine; Lisinopril; Oligopeptides; Pepstatins; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits; Radioimmunoassay; Renin; Spectrophotometry; Substrate Specificity | 1985 |
Impaired pulmonary conversion of angiotensin I to angiotensin II in rats exposed to chronic hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Chronic Disease; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Peptidyl-Dipeptidase A; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains | 1986 |
Specific measurement of angiotensin metabolites and in vitro generated angiotensin II in plasma.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Chromatography, High Pressure Liquid; Cross Reactions; Enalapril; Humans; In Vitro Techniques; Male; Radioimmunoassay | 1986 |
Prostacyclin generation by cultured human vascular endothelial cells with reference to angiotensin I-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Bradykinin; Captopril; Cells, Cultured; Endothelium; Enzyme Activation; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1986 |
Dual peroxidase and colloidal gold-labeling study of angiotensin converting enzyme and angiotensin-like immunoreactivity in the rat subfornical organ.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Astrocytes; Axons; Cross Reactions; Dendrites; Endothelium; Ependyma; Gold; Histocytochemistry; Horseradish Peroxidase; Immunologic Techniques; Male; Microscopy, Electron; Neurosecretory Systems; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Subfornical Organ | 1986 |
Response of isolated rat jejunum to angiotensin peptides.
Topics: Adrenalectomy; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Chlorides; Enalapril; Enalaprilat; Intestinal Absorption; Jejunum; Male; Nephrectomy; Potassium; Prazosin; Rats; Rats, Inbred Strains; Sodium; Water | 1986 |
Angiotensin I level and sporadic hypokalemic periodic paralysis.
Topics: Adolescent; Angiotensin I; Angiotensin II; Glomerular Filtration Rate; Humans; Hypertension, Renal; Hypokalemia; Male; Paralyses, Familial Periodic; Peptidyl-Dipeptidase A; Renin | 1986 |
Twenty-four hour changes in active and inactive renin after various oral doses of the converting enzyme inhibitor ramipril (HOE498) in normal man.
Topics: Administration, Oral; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Dose-Response Relationship, Drug; Humans; Male; Ramipril; Renin | 1986 |
Pressor sensitivity to angiotensin I and angiotensin II during the development of experimental renal hypertension in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Renal; Indoles; Male; Oligopeptides; Perindopril; Pressoreceptors; Rats; Rats, Inbred Strains; Teprotide | 1986 |
Cardiac and vascular actions of decapeptide angiotensin analogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Cardiovascular System; Enalapril; Enalaprilat; Male; Myocardial Contraction; Myocardium; Rabbits; Receptors, Angiotensin; Sarcolemma | 1986 |
[The effect of induced hyperthermia on kidney function in dogs].
Topics: 2,4-Dinitrophenol; Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Animals; Dinitrophenols; Dogs; Hyperthermia, Induced; Kidney; Renin; Vasopressins | 1986 |
Enhancing effects of angiotensin I on the vasopressin-stimulated water flow of toad bladder through increased cyclic AMP in mucosal cells.
Topics: Angiotensin I; Angiotensin II; Animals; Body Water; Bufo bufo; Cyclic AMP; Diuresis; Drug Interactions; Mucous Membrane; Urinary Bladder; Vasopressins | 1986 |
Interrelation between the renin-angiotensin system and kallikrein-kinin system in patients with essential hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Humans; Hypertension; Kallikreins; Kinins; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1986 |
Hyperoxia-induced converting enzyme insufficiency in conscious rat: cardiovascular effects.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Lung; Lysine Carboxypeptidase; Male; Microscopy, Electron; Oxygen; Peptidyl-Dipeptidase A; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains; Renin | 1987 |
Superficial nephron responses to peritubular capillary infusions of angiotensins I and II.
Topics: Angiotensin I; Angiotensin II; Animals; Capillaries; Enalapril; Enalaprilat; Glomerular Filtration Rate; Injections; Kidney Tubules; Male; Nephrons; Rats; Rats, Inbred Strains | 1987 |
Induction by fibroblast growth factor of angiotensin converting enzyme in vascular endothelial cells in vitro.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Captopril; Cells, Cultured; Edetic Acid; Endothelium; Enzyme Induction; Fibroblast Growth Factors; Growth Substances; Kinetics; Peptidyl-Dipeptidase A; Swine | 1987 |
Enzymatic formation of angiotensins II and III in the hindlimb circulation of dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Captopril; Dogs; Epinephrine; Female; Hindlimb; Iliac Artery; Male; Peptidyl-Dipeptidase A; Vasoconstriction | 1987 |
No substrate specificity of converting enzyme for N-terminal substituted angiotensin I in man.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Humans; Male; Substrate Specificity | 1987 |
Regulation of prostacyclin generation by angiotensin converting enzyme related substances in cultured human vascular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cells, Cultured; Endothelium; Epoprostenol; Humans; Peptidyl-Dipeptidase A | 1987 |
Heart and vascular wall as targets for tissue converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Vessels; Bradykinin; Bridged Bicyclo Compounds; Endothelium; Guinea Pigs; Heart; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardium; Ramipril; Rats | 1987 |
Elevated vascular angiotensin converting enzyme in chronic two-kidney, one clip hypertension in the dog.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Dogs; Dose-Response Relationship, Drug; Hypertension, Renal; Male; Muscle Contraction; Peptidyl-Dipeptidase A; Renin; Thiazolidines | 1987 |
Hypoxia does not alter angiotensin converting enzyme activity in hamster pulmonary microvessels.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Arterioles; Cheek; Cricetinae; Female; Hypoxia; Lung; Lung Transplantation; Mesocricetus; Methods; Microcirculation; Peptidyl-Dipeptidase A; Pulmonary Circulation; Veins; Venules | 1987 |
Thirst in Brattleboro rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Captopril; Crosses, Genetic; Drinking Behavior; Heterozygote; Homozygote; Isoproterenol; Male; Nephrectomy; Rats; Rats, Brattleboro; Rats, Inbred Strains; Rats, Mutant Strains; Saline Solution, Hypertonic; Sodium; Species Specificity; Thirst | 1988 |
Systemic effects resulting from topical ocular administration of SCH 33861, a novel ACE inhibitor ocular hypotensive agent.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Heart Rate; Intraocular Pressure; Male; Phenylbutyrates; Rabbits; Spiro Compounds | 1988 |
Alternative routes for angiotensin-I conversion: kinetics of the renin-angiotensin system in mouse plasma.
Topics: Angiotensin I; Angiotensin II; Animals; Kinetics; Mice; Mice, Inbred BALB C; Renin-Angiotensin System | 1988 |
Altered function of pulmonary endothelium following monocrotaline-induced lung vascular injury in rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Lung; Lung Diseases; Male; Monocrotaline; Muscle Relaxation; Potassium Chloride; Pulmonary Artery; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1988 |
Effects of chronic hyperoxia on the cardiovascular responses to vasoactive compounds in the rabbit.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Dinoprostone; Female; Heart Rate; Hemodynamics; Lung; Male; Nitroprusside; Organ Size; Oxygen; Prostaglandins E; Rabbits; Time Factors | 1988 |
Angiotensin reactivity in the cheek pouch of the renovascular hypertensive hamster.
Topics: Adenosine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cricetinae; Dose-Response Relationship, Drug; Female; Hypertension, Renovascular; Microcirculation | 1988 |
Vasopressin and angiotensin II stimulate oxygen uptake in the perfused rat hindlimb.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arginine Vasopressin; Hindlimb; Male; Nitroprusside; Norepinephrine; Oxygen; Oxygen Consumption; Phentolamine; Propranolol; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Subcellular localization in rat brain of angiotensin-related carboxypeptidase activity distinct from converting enzyme.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Carboxypeptidases; Hydrolysis; In Vitro Techniques; Rats; Rats, Inbred Strains; Subcellular Fractions | 1988 |
Role of sodium ions in angiotensin tachyphylaxis in the guinea-pig ileum and taenia coli.
Topics: Angiotensin I; Angiotensin II; Animals; Colon; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Sodium; Tachyphylaxis | 1988 |
Direct evidence for the local generation of vascular angiotensin II and its prostaglandin-mediated release from isolated hind legs in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Hindlimb; Indomethacin; Male; Meclofenamic Acid; ortho-Aminobenzoates; Prostaglandins; Rats; Rats, Inbred Strains | 1988 |
Conformationally restricted analogs of angiotensin II: titration and biological activity.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Guinea Pigs; Ileum; Molecular Conformation; Rats | 1988 |
A new syndrome: angiotensin-converting enzyme dysfunction syndrome: differential diagnosis and pathogenesis--case reports.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Bartter Syndrome; Humans; Hyperaldosteronism; Hypertension, Renovascular; Male; Middle Aged; Paralyses, Familial Periodic; Paralysis; Periodicity; Potassium; Renin; Syndrome | 1988 |
Enhancement of water intake by captopril (SQ14225), an angiotensin I-converting enzyme inhibitor, in the goldfish, Carassius auratus.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cyprinidae; Dose-Response Relationship, Drug; Drinking Behavior; Female; Goldfish; Male | 1988 |
Des-Leu angiotensin I: biosynthesis and drinking response.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Captopril; Carboxypeptidases; Cattle; Drinking; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Saralasin; Synaptosomes | 1988 |
Differential pressor and renal vascular reactivity to angiotensin II in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Species Specificity | 1987 |
Regulation of angiotensin II in rat adrenal gland.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Animals; Dehydration; Kinetics; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Renin; Saline Solution, Hypertonic | 1987 |
Effect of captopril on angiotensin II release from vascular tissues in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Hindlimb; Male; Nephrectomy; Rats; Rats, Inbred Strains | 1987 |
Angiotensin II-noradrenergic interactions in renovascular hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chronic Disease; Electric Stimulation; Hypertension, Renovascular; Norepinephrine; Rats; Renal Artery; Renin; Sympathetic Nervous System; Vascular Resistance | 1987 |
Direct release of angiotensins I and II from isolated rat kidney perfused with angiotensinogen-free medium.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; In Vitro Techniques; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Renin | 1987 |
The differential effect of aldosterone and dexamethasone on pressor responses in adrenalectomized rats.
Topics: Adrenal Glands; Adrenalectomy; Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Consciousness; Dexamethasone; Male; Norepinephrine; Pressoreceptors; Rats; Rats, Inbred Strains | 1988 |
Immunocytochemical and biochemical characterization of angiotensin I and II in cultured neuronal and glial cells from rat brain.
Topics: Angiotensin I; Angiotensin II; Animals; Brain Stem; Cells, Cultured; Hypothalamus; Immunohistochemistry; Neuroglia; Neurons; Rats; Rats, Inbred SHR; Rats, Inbred Strains | 1988 |
Angiotensin analogues that selectively augment the force of contraction of the isolated heart.
Topics: Angiotensin I; Angiotensin II; Animals; In Vitro Techniques; Myocardial Contraction; Pressoreceptors; Stimulation, Chemical; Structure-Activity Relationship; Vasoconstriction | 1988 |
Hydrolysis of angiotensin I by peptidases in homogenates of rat lung and aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Freezing; Hydrolysis; In Vitro Techniques; Lung; Rats; Rats, Inbred Strains | 1988 |
Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; In Vitro Techniques; Peptide Fragments; Rats; Receptors, Angiotensin; Saralasin | 1988 |
Biosynthesis of angiotensinogen and angiotensins by brain cells in primary culture.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Brain; Cells, Cultured; Chromatography, High Pressure Liquid; Leucine; Molecular Weight; Radioimmunoassay; Rats; Rats, Inbred Strains | 1988 |
Conversion of angiotensin I to angiotensin II by cathepsin A isoenzymes of porcine kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxypeptidases; Cathepsin A; Cathepsins; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Isoenzymes; Kidney; Kinetics; Swine | 1988 |
Enhanced tubuloglomerular feedback during peritubular infusions of angiotensins I and II.
Topics: Angiotensin I; Angiotensin II; Animals; Capillaries; Dose-Response Relationship, Drug; Feedback; Kidney Glomerulus; Kidney Tubules; Male; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Effects of angiotensins injected into various brain areas on luteinizing hormone release in female rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Brain; Female; Hypothalamus, Anterior; Hypothalamus, Posterior; Injections, Intraventricular; Luteinizing Hormone; Preoptic Area; Rats; Rats, Inbred Strains; Saralasin | 1987 |
Role of endothelial cells in responses of spontaneously hypertensive rat mesenteric arteries to norepinephrine and angiotensins.
Topics: Angiotensin I; Angiotensin II; Animals; Endothelium, Vascular; Hypertension; Male; Mesenteric Arteries; Norepinephrine; Rats; Rats, Inbred SHR; Vasoconstriction; Vasodilation | 1987 |
Levels of brain angiotensin in the spontaneously hypertensive rat and treatment with ramiprilat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Hypertension; Pyrroles; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spinal Cord | 1986 |
Characterization of a vasopressor substance generated in human plasma by incubation.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Blood; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hot Temperature; Humans; Isoflurophate; Pronase; Rats | 1986 |
Conversion of angiotensin-1 to angiotensin-2 by a latent endothelial cell peptidyl dipeptidase that is not angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cattle; Endopeptidases; Endothelium; Kinetics; Substrate Specificity | 1986 |
Regulation of renin angiotensins by gonadotropic hormones in cultured murine Leydig tumor cells. Release of angiotensin but not renin.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cells, Cultured; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Leydig Cell Tumor; Luteinizing Hormone; Male; Mice; Mice, Inbred C57BL; Radioimmunoassay; Renin; Testicular Neoplasms; Time Factors | 1986 |
Renal handling of angiotensins I and II in patients with renovascular hypertension.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Captopril; Female; Humans; Hypertension, Renovascular; Kidney; Male; Middle Aged; Renin | 1986 |
Effect of low doses of angiotensin II perfusion on the hypotensive action of captopril in anaesthetized normotensive and spontaneously hypertensive rats.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Catecholamines; Heart Rate; Hypertension; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1986 |
Central renin-angiotensin system and the pathogenesis of DOCA-salt hypertension in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Captopril; Desoxycorticosterone; Diuresis; Drinking; Hematocrit; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Pressoreceptors; Rats; Rats, Inbred WKY; Reflex; Renin; Renin-Angiotensin System; Sodium; Sodium Chloride; Vasopressins | 1986 |
Changes in central and peripheral renin-angiotensin system after furosemide injection.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Dogs; Furosemide; Male; Renin; Renin-Angiotensin System | 1986 |
Pre- and postsynaptic effects of angiotensins in the femoral artery of spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Captopril; Dinoprost; Endothelium; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Prostaglandins F; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Yohimbine | 1987 |
The role of the renin-angiotensin system in normotensive and hypertensive rats with varying renin status.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Captopril; Hypertension; Hypertension, Renal; Kidney Cortex; Male; Nephrectomy; Rats; Rats, Inbred Strains; Renal Artery; Renin; Renin-Angiotensin System; Urethane | 1987 |
Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cell Line; Endothelium; Intracellular Membranes; Renin; Renin-Angiotensin System | 1987 |
The response of retinal vasculature to angiotensin.
Topics: Angiotensin I; Angiotensin II; Animals; Cats; Female; Male; Optic Disk; Retina; Retinal Artery; Saralasin; Vasoconstriction | 1987 |
A sensitive method for precise measurement of endogenous angiotensins I, II&III in human plasma.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Chromatography, High Pressure Liquid; Humans; Iodine Radioisotopes; Radioimmunoassay | 1987 |
Effects of platelet-activating factor on conversion of angiotensin I to II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cattle; Cell Survival; Cells, Cultured; Endothelium; Platelet Activating Factor; Pulmonary Artery | 1987 |
Do peripheral and cerebroventricular injections of angiotensin II act at the same site? Studies on additivity of drinking.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Drinking; Female; Injections, Intravenous; Injections, Intraventricular; Injections, Subcutaneous; Rats; Rats, Inbred Strains; Saralasin | 1986 |
Angiotensin I and II in the assessment of baroreceptor function in fetal and neonatal sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Animals, Newborn; Blood Pressure; Fetus; Heart Rate; Norepinephrine; Pressoreceptors; Reflex; Sheep; Spinal Cord; Vagus Nerve | 1986 |
Biological activities of angiotensin II-(1-6)-hexapeptide and angiotensin II-(1-7)-heptapeptide in man.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Bartter Syndrome; Blood Pressure; Humans; Hyperaldosteronism; Infusions, Parenteral; Kinetics; Male; Peptide Fragments; Reference Values; Time Factors | 1986 |
Pregnancy causes a decrease in the number and affinity of myometrial angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Bradykinin; Female; Myometrium; Pregnancy; Receptors, Angiotensin; Saralasin; Sheep | 1986 |
The effect of angiotensin II upon electrogenic ion transport in rat intestinal epithelia.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Autonomic Agents; Biological Transport, Active; Colon; Electrolytes; Epithelium; In Vitro Techniques; Indomethacin; Intestinal Mucosa; Intestines; Jejunum; Male; ortho-Aminobenzoates; Piroxicam; Rats; Rats, Inbred Strains; Receptors, Angiotensin | 1987 |
Intraocular pressure and systemic blood pressure after administration of vasoactive substances in hypertensive and normal rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Bradykinin; Hypertension; Intraocular Pressure; Kallikreins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values | 1985 |
Angiotensin increases inositol phosphate content in anterior pituitary cells in culture: a relationship with its prolactin-stimulating activity.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Inositol Phosphates; Pituitary Gland, Anterior; Prolactin; Rats; Saralasin; Stimulation, Chemical; Sugar Phosphates | 1985 |
Effects of 100 percent oxygen on the cardiovascular responses to vasoactive compounds in the dog.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Body Weight; Dinoprostone; Dogs; Female; Heart Rate; Hemodynamics; Hyperbaric Oxygenation; Male; Organ Size; Prostaglandins E; Regional Blood Flow; Renin-Angiotensin System; Vascular Resistance | 1985 |
Conversion of angiotensin I to angiotensin II in the human foetoplacental vascular bed.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Blood Pressure; Captopril; Female; Humans; In Vitro Techniques; Placenta; Pregnancy; Saralasin; Vasoconstriction | 1985 |
A transition-state analogue inhibitor of human renin (H.261): test in vitro and a comparison with captopril in the anaesthetized baboon.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Female; Papio; Renin; Structure-Activity Relationship; Substrate Specificity | 1985 |
Effect of intracoronary captopril on coronary blood flow and regional myocardial function in dogs.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Female; Heart; Hemodynamics; Male; Proline | 1985 |
The pulmonary endothelial surface.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Angiotensin I; Angiotensin II; Animals; Bradykinin; Endothelium; Epoprostenol; Lung; Microscopy, Electron; Pneumonia; Rabbits | 1985 |
A role for the adrenal renin-angiotensin system in the regulation of potassium-stimulated aldosterone production.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Culture Techniques; Male; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium | 1985 |
Evidence for existence of angiotensins I and II in mature renin granules from rat kidney cortex.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cell Fractionation; Centrifugation, Density Gradient; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Histocytochemistry; Juxtaglomerular Apparatus; Kidney Cortex; Male; Rats; Renin; Sodium Chloride | 1985 |
Captopril mediated decrease of aortic regurgitation.
Topics: Angiotensin I; Angiotensin II; Aortic Valve Insufficiency; Blood Pressure; Captopril; Heart Rate; Humans; Radioimmunoassay; Stroke Volume | 1985 |
Bovine and human endothelial cell production of neutrophil chemoattractant activity in response to components of the angiotensin system.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Cattle; Cells, Cultured; Chemotaxis, Leukocyte; Diethylcarbamazine; Dose-Response Relationship, Drug; Endothelium; Humans; Indomethacin; Neutrophils; Saralasin | 1985 |
Blockade of the pressor response to angiotensins I and II in the bullfrog, Rana catesbeiana.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Norepinephrine; Phenoxybenzamine; Pulse; Rana catesbeiana; Structure-Activity Relationship | 1985 |
Action of brain cathepsin B, cathepsin D, and high-molecular-weight aspartic proteinase on angiotensins I and II.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aspartic Acid Endopeptidases; Catalysis; Cathepsin B; Cathepsin D; Cathepsins; Cattle; Endopeptidases; Humans; Hydrolysis; In Vitro Techniques | 1985 |
Effects of angiotensin I and II and their interactions with some prostanoids in perfused human umbilical arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Captopril; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Perfusion; Pregnancy; Prostaglandins; Saralasin; Umbilical Arteries; Vasoconstriction | 1985 |
Angiotensin extraction by trout tissues in vivo and metabolism by the perfused gill.
Topics: Angiotensin I; Angiotensin II; Animals; Carbon Radioisotopes; Gills; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Perfusion; Salmonidae; Sucrose; Tissue Distribution; Trout | 1986 |
Hormonal and pharmacological alteration of angiotensinogen secretion from rat hepatocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Colchicine; Cycloheximide; Dactinomycin; Immune Sera; In Vitro Techniques; Kinetics; Liver; Male; Puromycin; Radioimmunoassay; Rats; Rats, Inbred Strains; Serum Albumin; Tunicamycin; Vinblastine | 1986 |
Influence of angiotensin II on the concentration of arterial plasma electrolytes in anaesthetized sheep.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Calcium; Chlorides; Dose-Response Relationship, Drug; Electrolytes; Epinephrine; Female; Norepinephrine; Potassium; Sheep; Sodium | 1985 |
Evidence for the existence of des-Asp1-angiotensin II in human uterine and adrenal tissues.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin III; Chromatography, High Pressure Liquid; Epididymis; Female; Humans; Male; Radioimmunoassay; Renin-Angiotensin System; Salivary Glands; Testis; Uterus | 1985 |
Characterization of angiotensin I, II, and III from mouse as position-5 isoleucine [Ile5] angiotensins. An HPLC Study.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Rats; Submandibular Gland | 1985 |
Angiotensin and thirst: studies with a converting enzyme inhibitor and a receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Teprotide; Thirst | 1974 |
Effect of SQ20881 and captopril on pulmonary angiotensin II formation and blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Lung; Male; Oligopeptides; Proline; Teprotide | 1983 |
The effect of angiotensins I, II, and III on formation of cyclic GMP in murine neuroblastoma clone N1E-115.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Clone Cells; Cyclic GMP; Mice; Neuroblastoma; Neurons; Receptors, Angiotensin | 1984 |
Kallikrein-kinin and renin-angiotensin systems in rat renal lymph.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, Gel; Kallikreins; Kidney; Kinins; Lymph; Male; Molecular Weight; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Inbred Strains; Renin; Renin-Angiotensin System | 1984 |
Acute hemodynamic and hormonal effects of MK-521 in congestive heart failure.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dipeptides; Female; Heart Failure; Hemodynamics; Hormones; Humans; Lisinopril; Male; Middle Aged; Renin; Time Factors | 1984 |
The influence of ACE-inhibition by captopril on renal formation and metabolism of angiotensins I and II in patients with renovascular hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Captopril; Catheterization; Female; Femoral Artery; Humans; Hypertension, Renovascular; Kidney; Male; Middle Aged; Proline; Renal Veins | 1984 |
Hormonal and metabolic effects of angiotensin converting enzyme inhibitors. Possible differences between enalapril and captopril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dipeptides; Enalapril; Humans; Hypertension; Kinins; Posture; Potassium; Proline; Prostaglandins; Renin; Renin-Angiotensin System; Sodium | 1984 |
Enalapril in treatment of hypertension with renal artery stenosis. Changes in blood pressure, renin, angiotensin I and II, renal function, and body composition.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Body Composition; Creatinine; Dipeptides; Drug Evaluation; Enalapril; Female; Heart Rate; Humans; Hypertension; Kidney; Male; Middle Aged; Posture; Potassium; Renal Artery Obstruction; Renin; Sodium | 1984 |
Mechanism of pressor effects by angiotensin in the nucleus tractus solitarius of rats.
Topics: Angiotensin I; Angiotensin II; Animals; Autonomic Nerve Block; Biomechanical Phenomena; Blood Pressure; Capillaries; Cardiovascular System; Hypophysectomy; Male; Medulla Oblongata; Microinjections; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Respiratory Center; Vasopressins | 1984 |
Angiotensin I conversion by human and rat chymotryptic proteinases.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cathepsin G; Cathepsins; Chromatography, High Pressure Liquid; Chymases; Chymotrypsin; Endopeptidases; Humans; Mast Cells; Neutrophils; Peptidyl-Dipeptidase A; Rats; Salivary Glands; Serine Endopeptidases; Skin; Substrate Specificity | 1984 |
Brain angiotensin: on the way to becoming a well-studied neuropeptide system.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Brain; DNA; Mice; Neurons; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Transcription, Genetic | 1984 |
Renal prostaglandin E in the hypotensive mechanism of MK-421 in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biomechanical Phenomena; Blood Pressure; Consciousness; Dipeptides; Enalapril; Hypertension; Kidney; Male; Norepinephrine; Prostaglandins E; Rats; Rats, Inbred Strains; Sodium; Vasopressins | 1984 |
Effects of locally generated angiotensin II on noradrenergic transmission in guinea-pig isolated atria.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Function; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Synaptic Transmission | 1984 |
Evidence for a putatively new angiotensin II-generating enzyme in the vascular wall.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Vessels; Dogs; Female; In Vitro Techniques; Macaca; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Sulfhydryl Compounds; Thiazolidines | 1984 |
Mechanism of the pressor response to tetradecapeptide renin substrate in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Male; Nephrectomy; Pepstatins; Peptides; Phenylephrine; Rats; Rats, Inbred SHR; Renin | 1984 |
Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Brain; Captopril; Chromatography, High Pressure Liquid; Female; Hypertension; Male; Nephrectomy; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tissue Distribution | 1984 |
Biochemical monitoring of vasoactive peptides during angiotensin converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Captopril; Cross Reactions; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Kinetics; Peptidyl-Dipeptidase A; Radioimmunoassay; Renin | 1983 |
Clinical pharmacology of enalapril.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biological Availability; Blood Pressure; Enalapril; Half-Life; Humans; Hypertension; Renin | 1984 |
Aminopeptidase A is angiotensinase A. II. Biochemical studies on aminopeptidase A and M in rat kidney homogenate.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Calcium; CD13 Antigens; Fluorometry; Glutamyl Aminopeptidase; Ion Channels; Kidney; Kidney Glomerulus; Kinetics; Male; Rats; Rats, Inbred Strains | 1982 |
Enhancement by locally generated angiotensin II of release of the adrenergic transmitter in the isolated rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dipeptides; Enalapril; Guanethidine; Kidney; Male; Neurotransmitter Agents; Norepinephrine; Pregnenediones; Pressure; Rats; Rats, Inbred Strains; Renin; Serum Albumin, Bovine; Tetrodotoxin | 1983 |
Kinin receptors and angiotensin converting enzyme in rabbits basilar arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Basilar Artery; Bradykinin; Cycloheximide; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rabbits; Receptors, Bradykinin; Receptors, Cell Surface; Serotonin; Time Factors | 1983 |
Effect of chronic treatment with captopril on reactivity of aortic smooth muscle from normotensive and renal hypertensive rats.
Topics: Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Body Weight; Captopril; Female; Hypertension, Renal; Isoproterenol; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Organ Size; Phenylephrine; Potassium Chloride; Proline; Rats; Rats, Inbred Strains | 1983 |
Action of angiotensins I, II, and III on aldosterone production by isolated rat adrenal zona glomerulosa cells. importance of metabolism and conversion of peptides in vitro.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cells, Cultured; Corticosterone; Dose-Response Relationship, Drug; Rats; Teprotide | 1980 |
Specific inhibition of renin by an angiotensinogen analog: studies in sodium depletion and renin-dependent hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Hypertension; Macaca fascicularis; Male; Oligopeptides; Peptidyl-Dipeptidase A; Renin; Sodium; Teprotide | 1980 |
Screening for rabbit brain neuropeptide-metabolizing peptidases. Inhibition of endopeptidase B by bradykinin potentiating peptide 9a (SQ 20881).
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Brain; Gonadotropin-Releasing Hormone; Isoenzymes; Kinetics; Neurotensin; Oligopeptides; Rabbits; Substance P; Substrate Specificity; Teprotide | 1980 |
Analysis of the mechanism of acute decrease of blood pressure induced by captopril (SQ 14,225) in dogs by the use of aprotinin, SAR1-ILE8-angiotensin II and indomethacin.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Aprotinin; Blood Pressure; Bradykinin; Captopril; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Indomethacin; Male; Proline | 1981 |
Comparison of intrarenal and extrarenal converting-enzyme inhibition by SQ 20 881 on canine renal blood flow.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs; Female; Injections, Intra-Arterial; Injections, Intravenous; Kidney; Male; Oligopeptides; Renal Circulation; Teprotide; Vasodilation | 1981 |
Neuropeptides in the pineal gland? A critical immunocytochemical study.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Immune Sera; Immunoassay; Male; Microscopy, Electron; Pineal Gland; Rats; Rats, Inbred Strains; Staining and Labeling | 1981 |
Hormonal and blood pressure changes during converting enzyme inhibition by teprotide.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Female; Humans; Hypertension, Renal; Kidney Transplantation; Oligopeptides; Radioimmunoassay; Renin; Teprotide | 1981 |
Angiotensin I converting enzyme activity in portal vein studied in normotensive rats and in models of primary and secondary hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Hypertension; Male; Muscle, Smooth, Vascular; Oligopeptides; Portal Vein; Rats; Rats, Inbred Strains; Teprotide | 1981 |
Alteration by kallikrein and bradykinin of the conversion of angiotensin I to angiotensin II in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Biotransformation; Bradykinin; Female; Kallikreins; Lung; Male; Muscle Contraction; Rats; Teprotide | 1982 |
Effects of SQ 20881 and captopril on mesenteric, renal, and iliac vasculatures.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Iliac Artery; Iliac Vein; Male; Mesenteric Arteries; Mesenteric Veins; Oligopeptides; Proline; Regional Blood Flow; Renal Circulation; Teprotide | 1983 |
Neural mechanisms affecting pressor responses to angiotensins in the Pekin duck, Anas platyrhynchos.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Ducks; Kinetics; Male; Pentobarbital; Phenobarbital; Teprotide | 1983 |
Potentiation of bradykinin by inhibitors of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Drug Synergism; Female; Hydrolysis; Kinetics; Oligopeptides; Rats; Rats, Inbred Strains; Teprotide | 1983 |
Possible prostacyclin-mediated vascular effect of angiotensin II in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Animals; Aspirin; Colon; Epoprostenol; Female; Iloprost; Lung; Lysine; Male; Nicotine; Pulmonary Circulation; Rats | 1983 |
Vascular renin-angiotensin: a possible autocrine or paracrine system in control of vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Dogs; Hydrogen-Ion Concentration; Kinetics; Muscle, Smooth, Vascular; Renin; Renin-Angiotensin System | 1984 |
The afferent glomerular arteriole: immunocytochemical and electrophysiological investigations.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arterioles; Cricetinae; Cricetulus; Electrophysiology; Guinea Pigs; Histocytochemistry; Immunochemistry; Kidney Glomerulus; Mice; Rats; Rats, Inbred Strains; Renal Circulation; Renin; Swine | 1984 |
Alterations in responses to bradykinin, angiotensin I, and angiotensin II during the induction phase of one-kidney, one-wrapped hypertension and associated arterial disease in rabbits.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Disease Models, Animal; Hypertension, Renal; Hypertension, Renovascular; Male; Nephrectomy; Peptidyl-Dipeptidase A; Perinephritis; Rabbits; Renin | 1980 |
Postnatal development of the renin-angiotensin system in rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Endopeptidases; Kidney; Male; Rats; Renin | 1980 |
Hormonal responses to angiotensin blockade. Comparison between receptor antagonism and converting enzyme inhibition.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Rats; Receptors, Angiotensin; Receptors, Cell Surface; Renin; Saralasin | 1980 |
Inhibitor of angiotensin I converting enzyme: (4R)-3-[(2S)-3-mercapto-2-methylpropanoyl]-4-thiazolidinecarboxylic acid (YS-980).
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; In Vitro Techniques; Kinetics; Norepinephrine; Pentobarbital; Pentolinium Tartrate; Rabbits; Renin; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1980 |
Comparative study of an angiotensin-II analog and a converting enzyme inhibitor.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Peptidyl-Dipeptidase A; Proline; Renin; Saralasin | 1980 |
Effects of angiotensin I converting enzyme inhibitor (SQ 14225) on control of aldosterone.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Female; Potassium; Proline; Rabbits; Renin | 1980 |
The effect of captopril on blood pressure and angiotensins I, II and III in sodium-depleted dogs: problems associated with the measurement of angiotensin II after inhibition of converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dogs; Male; Proline; Radioimmunoassay; Sodium | 1980 |
Effect of inhibition of converting enzyme on inactive renin in the circulation of salt-replete and salt-deplete normal subjects.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Kidney; Proline; Renin; Sodium Chloride | 1980 |
Role of extrarenal and intrarenal converting enzyme inhibition in renal vasodilator response to intravenous captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Captopril; Dogs; Female; Femoral Artery; Kidney; Male; Proline; Renal Artery; Vascular Resistance; Vasoconstriction | 1980 |
des-Asp-angiotensin I: its identification in rat blood and confirmation as a substrate for converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Dose-Response Relationship, Drug; Hormones; Infusions, Parenteral; Male; Peptidyl-Dipeptidase A; Rats | 1981 |
Angiotensin-converting enzyme activity in ocular fluids.
Topics: Angiotensin I; Angiotensin II; Animals; Aqueous Humor; Bradykinin; Dipeptides; Eye Color; Female; Humans; Male; Peptidyl-Dipeptidase A; Rabbits; Tears | 1981 |
Effect of captopril on the blood pressure response to angiotensin I in turkeys.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Epinephrine; Male; Proline; Time Factors; Turkeys | 1981 |
Evidence for bradykinin potentiation by angiotensin congeners in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Vessels; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Infusions, Parenteral; Male; Peptidyl-Dipeptidase A; Rats; Saralasin; Vasoconstriction | 1981 |
The fate of circulating biologically active peptides in the lungs.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Crotalid Venoms; Endopeptidases; Kinins; Lung; Organ Specificity; Peptides; Peptidyl-Dipeptidase A; Pulmonary Circulation; Rats | 1980 |
Non-respiratory functions of the lung in the perinatal period.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Coagulation; Blood Pressure; Bradykinin; Fetus; Fibrinolysis; Gestational Age; Humans; Infant, Newborn; Kallikreins; Kinins; Lung; Peptidyl-Dipeptidase A; Placenta; Rabbits; Renin; Respiratory Distress Syndrome, Newborn | 1980 |
Antihypertensive effects of the novel converting-enzyme inhibitor YS 980 in spontaneously hypertensive rats.
Topics: 3-Mercaptopropionic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Bradykinin; Catecholamines; Hypertension; Male; Rats; Sulfhydryl Compounds; Thiazoles; Thiazolidines | 1981 |
Three new long-acting converting-enzyme inhibitors: relationship between plasma converting-enzyme activity and response to angiotensin I.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Blood Pressure; Dose-Response Relationship, Drug; Humans; Male; Peptidyl-Dipeptidase A; Renin | 1981 |
Effects of continuous angiotensin I-converting enzyme blockade on blood pressure, sympathetic activity and renin-angiotensin system in stroke-prone spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Captopril; Disease Susceptibility; Hypertension; Male; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Renin; Sympathetic Nervous System | 1981 |
Characterization of angiotensin receptors on bovine adrenal fasciculata cells.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Binding, Competitive; Calcium; Cattle; Cyclic AMP; Potassium; Receptors, Angiotensin; Receptors, Cell Surface | 1981 |
Vasoactive peptides and hypertension: role of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; Humans; Hypertension; Hypertension, Renovascular; Peptidyl-Dipeptidase A; Renin | 1981 |
Inhibition of the renin-angiotensin system. A new approach to the therapy of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Captopril; Enzyme Activation; Humans; Hypertension; Peptidyl-Dipeptidase A; Renin | 1981 |
Tonin, an esteroprotease from rat submaxillary glands.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Macromolecular Substances; Male; Peptidyl-Dipeptidase A; Rats; Submandibular Gland; Substrate Specificity | 1981 |
The action of angiotensin on the isolated perfused cat heart.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cats; Drug Interactions; Heart; In Vitro Techniques; Reserpine; Sympatholytics; Sympathomimetics | 1981 |
Renin and angiotensin: the complete system within the neuroblastoma x glioma cell.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cell Line; Cricetinae; Glioma; Hybrid Cells; Mice; Neuroblastoma; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Renin | 1981 |
Renin, angiotensins, and angiotensin-converting enzyme in neuroblastoma cells: evidence for intracellular formation of angiotensins.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cell Line; Clone Cells; Hydrogen-Ion Concentration; Kinetics; Mice; Neoplasms, Experimental; Neuroblastoma; Peptidyl-Dipeptidase A; Rats; Renin; Species Specificity | 1981 |
Converting enzyme inhibition and modulation of plasma renin activity with captopril in anesthetized rats.
Topics: Acetylcholine; Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Isoproterenol; Male; Norepinephrine; Proline; Rats; Rats, Inbred Strains; Renin | 1981 |
[Relationship between the kininase and angiotensin-converting lung functions in rabbits with cerebroischemic and renovascular hypertension].
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Brain Ischemia; Carboxypeptidases; Dose-Response Relationship, Drug; Hypertension, Renal; Hypertension, Renovascular; Lung; Lysine Carboxypeptidase; Peptidyl-Dipeptidase A; Rabbits | 1982 |
Juxtaglomerular cells grown as monolayer cell culture contain renin, angiotensin I-converting enzyme, and angiotensin I and II/III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cells, Cultured; Cytoplasmic Granules; Endoplasmic Reticulum; Kidney Glomerulus; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Renin | 1982 |
Separation of angiotensins and assay of angiotensin-generating enzymes by high-performance liquid chromatography.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Chromatography, High Pressure Liquid; Kinetics; Peptides; Peptidyl-Dipeptidase A; Renin | 1982 |
Release of beta-lipotropin- and beta-endorphin-like material induced by angiotensin in the conscious rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; beta-Endorphin; beta-Lipotropin; Captopril; Dexamethasone; Drug Interactions; Endorphins; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Saralasin; Species Specificity | 1982 |
Reversal by acetylsalicylic acid of the captopril-induced inhibition of angiotensin converting enzyme in the hindquarters of guinea-pig.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspirin; Biotransformation; Blood Pressure; Captopril; Colon; Diet; Female; Guinea Pigs; Male; Proline | 1982 |
Immunocytochemistry of the renin-angiotensin system: renin, angiotensinogen, angiotensin I, angiotensin II, and converting enzyme in the kidneys of mice, rats, and tree shrews.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Arterioles; Histocytochemistry; Immunochemistry; Juxtaglomerular Apparatus; Kidney; Male; Mice; Peptidyl-Dipeptidase A; Rats; Renin; Tupaiidae | 1982 |
Angiotensin does contribute to drinking induced by caval ligation in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Drinking Behavior; Male; Proline; Rats; Renin; Thirst; Vena Cava, Inferior | 1982 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; Humans; Hydralazine; Hydrocortisone; Hypertension; Middle Aged; Nifedipine; Peptidyl-Dipeptidase A; Pyridines; Renin; Renin-Angiotensin System | 1982 |
Brain angiotensinogen: in vitro synthesis and chromatographic characterization.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Blood-Brain Barrier; Brain; Chromatography, Gel; Concanavalin A; Culture Techniques; Cycloheximide; Cytosol; Endopeptidases; Female; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Vinblastine | 1983 |
Proteolytic conversion of angiotensins in rat brain tissue.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Biotransformation; Brain Chemistry; In Vitro Techniques; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Synaptic Membranes | 1983 |
Significance of renin-angiotensin system during and after surface-induced simple hypothermia in open-heart surgery.
Topics: Adolescent; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cardiac Surgical Procedures; Child; Dogs; Female; Humans; Hypothermia, Induced; Male; Middle Aged; Peptidyl-Dipeptidase A; Renal Circulation; Renin; Renin-Angiotensin System | 1983 |
Attenuation of pressor responses to intracerebroventricular angiotensin I by angiotensin converting enzyme inhibitors and their effects on systemic blood pressure in conscious rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain; Captopril; Cerebral Ventricles; Dipeptides; Enalapril; Hypertension; Male; Peptidyl-Dipeptidase A; Proline; Rats; Rats, Inbred Strains | 1983 |
Effect of the angiotensin I converting enzyme inhibitor, MK-421, on experimentally induced drinking.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dehydration; Dipeptides; Dose-Response Relationship, Drug; Drinking; Enalapril; Estrus; Female; Heart Rate; Isoproterenol; Pregnancy; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic | 1982 |
Effect of hypoxia on the conversion of angiotensin I to II in cultured porcine pulmonary endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cells, Cultured; Endothelium; Kinetics; Oxygen; Peptidyl-Dipeptidase A; Pulmonary Artery; Swine | 1983 |
Biochemistry of the renin-angiotensin system. Introduction.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Humans; Kinins; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1983 |
[The renin-angiotensin system of the brain].
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Brain; Humans; Mice; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Vasopressins | 1983 |
Intrarenal angiotensin I conversion at normal and reduced renal blood flow in the dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Blood Pressure; Dipeptides; Dogs; Enalaprilat; Female; Glomerular Filtration Rate; Kidney; Male; Radioimmunoassay; Renal Artery; Renal Circulation | 1983 |
Enalapril in the treatment of hypertension with renal artery stenosis.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Creatinine; Dipeptides; Enalapril; Female; Humans; Hypertension, Renovascular; Male; Middle Aged; Potassium; Renin; Sodium; Time Factors; Urea | 1983 |
Extrarenal angiotensin-forming enzymes.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Chemical Phenomena; Chemistry; Endopeptidases; Enzyme Activation; Humans; In Vitro Techniques; Neutrophils; Peptidyl-Dipeptidase A; Serine Endopeptidases | 1983 |
Levels of renin, angiotensin I and II, angiotensin-converting enzyme and aldosterone in infancy and childhood.
Topics: Adolescent; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Peptidyl-Dipeptidase A; Potassium; Reference Values; Renin; Sodium | 1983 |
Long-term survival and aldosterone secretion pattern of aldosteronoma in culture.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Bucladesine; Cell Survival; Cells, Cultured; Humans; Hyperaldosteronism | 1983 |
Measurement of low angiotensin concentrations after ethanol and Dowex extraction procedures.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anion Exchange Resins; Dipeptides; Enalapril; Ethanol; Humans; Indoles; Kidney; Lisinopril; Male; Radioimmunoassay; Rats; Resins, Synthetic | 1984 |
Coronary vascular actions of the converting enzyme inhibitor, enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Captopril; Cats; Coronary Vessels; Dipeptides; Dose-Response Relationship, Drug; Enalapril; In Vitro Techniques; Kinetics; Vasoconstriction | 1984 |
Generation and elimination of angiotensins I and II in the kidney, liver and lung.
Topics: Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Humans; Hypertension; Kidney; Liver; Lung; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1983 |
Angiotensin stimulates beta-endorphin release from anterior pituitary gland cell cultures of rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; beta-Endorphin; Captopril; Cells, Cultured; Drug Interactions; Endorphins; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Renin | 1984 |
Inhibition of adenylate cyclase in rat adrenal glomerulosa cells by angiotensin II.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adenylyl Cyclase Inhibitors; Adrenal Glands; Adrenocorticotropic Hormone; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cations, Monovalent; Guanosine Triphosphate; Lithium; Rats; Rats, Inbred Strains; Sodium | 1984 |
Generation of angiotensins in cultured pheochromocytoma cells.
Topics: Adrenal Medulla; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cell Line; Peptidyl-Dipeptidase A; Pheochromocytoma; Rats; Renin | 1984 |
Evidence for an angiotensin II-like material and for a rapid metabolism of angiotensin II in the rat brain.
Topics: Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Brain; Chromatography, High Pressure Liquid; Male; Metabolic Clearance Rate; Peptides; Radioimmunoassay; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Receptors, Cell Surface | 1984 |
Angiotensin II in the renal excretory response to behavioral stress in conscious dogs.
Topics: Angiotensin I; Angiotensin II; Animals; Avoidance Learning; Captopril; Dogs; Glomerular Filtration Rate; Humans; Kidney; Male; Renal Circulation; Saralasin; Sodium; Stress, Psychological | 1983 |
[Action of two thiol proteinases from the spleen which are active in neutral media on vasoactive peptides].
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Bradykinin; Cattle; Cysteine Endopeptidases; Endopeptidases; Gastrointestinal Hormones; Kallidin; Kinetics; Spleen; Substrate Specificity | 1983 |
The converting enzyme inhibitor captopril stimulates prostacyclin synthesis by isolated rat aorta.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Blood Vessels; Captopril; Epoprostenol; In Vitro Techniques; Proline; Rats | 1983 |
The renin-angiotensin system and drinking in the euryhaline flounder, Platichthys flesus.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Captopril; Chlorides; Drinking; Fishes; Fresh Water; Osmolar Concentration; Renin-Angiotensin System; Seawater; Sodium | 1983 |
Effect of captopril on the renin-angiotensin system in hypertensive children.
Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Child; Humans; Hypertension; Proline; Renin; Renin-Angiotensin System | 1983 |
Vascular effects and metabolism of angiotensins and their metabolites in the isolated perfused rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation; Renin | 1983 |
Temperature sensitivity of the renin-angiotensin system in Ambystoma tigrinum.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Isoproterenol; Kidney; Male; Muscle, Smooth, Vascular; Radioimmunoassay; Renin; Renin-Angiotensin System; Temperature; Urodela | 1984 |
Stimulation of spontaneous and dopamine-inhibited prolactin release from anterior pituitary reaggregate cell cultures by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Anti-Bacterial Agents; Captopril; Cells, Cultured; Dopamine; Dose-Response Relationship, Drug; Male; Oligopeptides; Peptides; Pituitary Gland, Anterior; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains | 1984 |
Effects of dehydration and renin on vasopressin concentration in the subfornical organ area.
Topics: Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Dehydration; Hematocrit; Injections, Intraventricular; Male; Neurosecretory Systems; Rats; Rats, Inbred Strains; Renin; Subfornical Organ | 1984 |
Angiotensin III-induced dipsogenic and pressor responses in rodents.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Drinking Behavior; Gerbillinae; Male; Neurosecretory Systems; Rats; Rats, Inbred Strains; Rodentia; Species Specificity | 1984 |
Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Male; Muscle Tonus; Muscle, Smooth, Vascular; Oligopeptides; Perfusion; Rats; Rats, Inbred Strains; Renin; Vasoconstrictor Agents | 1984 |
Disappearance of enkephalins in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Assay; Captopril; Colon; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalin, Methionine; Enkephalins; Indomethacin; Lung; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains; Stomach | 1984 |
The vasopressor action of the renin-angiotensin system in the rat snake, Ptyas korros.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Kidney; Male; Norepinephrine; Phentolamine; Renin-Angiotensin System; Reserpine; Saralasin; Snakes; Tissue Extracts | 1984 |
Interactions between brain angiotensin and prostaglandins in rats.
Topics: Alprostadil; Angiotensin I; Angiotensin II; Angiotensins; Animals; Cerebral Ventricles; Epoprostenol; Injections, Intraventricular; Male; Prostaglandins E; Rats; Rats, Inbred Strains; Renin-Angiotensin System | 1984 |
Prostaglandins and the contractile effect of angiotensin I and II in the uterus isolated from ovariectomized rats. Influences of indomethacin and 17-beta estradiol.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Castration; Estradiol; Female; In Vitro Techniques; Indomethacin; Prostaglandins; Rats; Rats, Inbred Strains; Uterine Contraction; Uterus | 1984 |
New inhibitors of human renin tested in vitro and in vivo in the anaesthetized baboon.
Topics: Anesthesia, General; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cathepsin D; Chemical Phenomena; Chemistry; Dogs; Humans; Infusions, Parenteral; Papio; Peptides; Rats; Renin; Sodium | 1983 |
Effects of circulating renin substrate on renal function in isolated perfused rat kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Angiotensins; Animals; Chromatography, High Pressure Liquid; In Vitro Techniques; Kidney; Kinetics; Perfusion; Rats; Renin | 1983 |
Feedback pressure-flow responses in normal and angiotensin-prostaglandin-blocked rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Capillaries; Feedback; Glomerular Filtration Rate; Hydrostatic Pressure; Kidney Glomerulus; Kidney Tubules; Male; Nephrons; Pressure; Prostaglandin Antagonists; Rats; Rats, Inbred Strains | 1984 |
Effects of renal arterial angiotensin I infusion on glomerular dynamics in sodium replete dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Dogs; Female; Glomerular Filtration Rate; Hemodynamics; Infusions, Intra-Arterial; Kidney Glomerulus; Male; Mathematics; Renal Artery; Renal Circulation; Renin-Angiotensin System; Sodium; Vascular Resistance | 1984 |
Combined high-performance liquid chromatography-radioimmunoassay for the characterization and quantitative measurement of neuropeptides.
Topics: Angiotensin I; Angiotensin II; Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Endorphins; Guinea Pigs; Myocardium; Nerve Tissue Proteins; Radioimmunoassay; Rats; Spectrophotometry, Ultraviolet | 1984 |
A role for central angiotensin in regulation of blood pressure at the nucleus tractus solitarius.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Brain Mapping; Efferent Pathways; Male; Medulla Oblongata; Rats; Rats, Inbred Strains | 1984 |
Chemical structure of angiotensin in the bullfrog Rana catesbeiana.
Topics: Amino Acid Sequence; Amino Acids; Angiotensin I; Angiotensin II; Angiotensins; Animals; Chromatography, High Pressure Liquid; Female; Kidney; Male; Peptide Fragments; Rana catesbeiana | 1983 |
[Renin-angiotensin system under extracorporeal circulation during heart valve surgery].
Topics: Angiotensin I; Angiotensin II; Aortic Valve; Cardiopulmonary Bypass; Female; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Lysine Carboxypeptidase; Male; Middle Aged; Mitral Valve; Renin-Angiotensin System | 1983 |
The high-performance liquid chromatographic analysis of diastereomers and structural analogs of angiotensins I and II.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Angiotensins; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Peptide Fragments; Stereoisomerism | 1983 |
Mechanisms of the central pressor action of angiotensin II in conscious rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Carotid Arteries; Injections, Intra-Arterial; Male; Rats; Rats, Inbred Strains; Saralasin; Vascular Resistance; Vasoconstriction | 1984 |
Cardiovascular responsiveness to physiological agonists of male rats made hypertensive by long-term exposure to cadmium.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cadmium; Catechol O-Methyltransferase Inhibitors; Copper; Epinephrine; Heart; Heart Rate; Hemodynamics; Histamine; Hypertension; Kidney; Male; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Serotonin; Zinc | 1984 |
Effects of angiotensins of the motility of human sperm.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Humans; In Vitro Techniques; Male; Saralasin; Sperm Motility | 1984 |
Separation of radioiodinated angiotensins by chromatofocusing in minicolumns.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Chromatography, Ion Exchange; Iodine Radioisotopes; Isoelectric Point; Rats; Receptors, Angiotensin; Saralasin | 1984 |
Chronotropic effects of angiotensin I, angiotensin II, bradykinin and vasopressin in guinea pig atria.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Catecholamines; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Indomethacin; Male; Reserpine; Saralasin; Vasopressins | 1982 |
In vivo conversion of [des-Asp1]-angiotensin I to [des-Asp1]-angiotensin II in conscious sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Captopril; Sheep | 1982 |
Measurement and localization of angiotensin-like immunoreactivity in juxtaglomerular cells of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Chromatography, Gel; Immunoenzyme Techniques; Kidney; Kidney Glomerulus; Male; Radioimmunoassay; Rats | 1982 |
Captopril in renovascular hypertension: long-term use in predicting surgical outcome.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension, Renal; Hypertension, Renovascular; Kidney; Male; Middle Aged; Preoperative Care; Prognosis; Proline; Renin | 1982 |
Captopril in the long-term treatment of essential hypertension: changes in the renin-angiotensin-aldosterone system.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Electrolytes; Humans; Hypertension; Long-Term Care; Proline; Renin; Renin-Angiotensin System | 1982 |
Rapid conversion of angiotensin I to angiotensin II by neutrophil and mast cell proteinases.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Angiotensins; Captopril; Cathepsin G; Cathepsins; Chromatography, High Pressure Liquid; Chymosin; Humans; Mast Cells; Neutrophils; Serine Endopeptidases; Skin; Time Factors | 1982 |
Drinking in goats as effect of simultaneous intravenous infusions of angiotensin (I or II) and hypertonic NaCl or mannitol.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Drinking; Female; Goats; Infusions, Parenteral; Male; Mannitol; Saline Solution, Hypertonic; Sodium Chloride | 1981 |
Pharmacological responses of the microvasculature of transplanted cardiac tissue.
Topics: Acetylcholine; Adenosine; Angiotensin I; Angiotensin II; Animals; Coronary Circulation; Cricetinae; Female; Isoproterenol; Microcirculation; Models, Cardiovascular; Nitroglycerin; Norepinephrine; Vasodilation | 1982 |
The specificity of angiotensin-antisera. A cautionary note.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Antibody Specificity; Cross Reactions; Immune Sera | 1983 |
Control of renal function by intrarenal angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Body Water; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Kidney; Natriuresis; Potassium; Regional Blood Flow; Saralasin | 1983 |
Angiotensin synthesis in the brain and increased turnover in hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Brain; Hypertension; Nephrectomy; Radioimmunoassay; Rats | 1983 |
Effects on renal hemodynamics of intra-arterial infusions of angiotensins I and II.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Dogs; Female; Glomerular Filtration Rate; Infusions, Parenteral; Kidney; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Renal Circulation; Vascular Resistance | 1983 |
Kinin-inactivating enzyme from the mushroom Tricholoma conglobatum. VI. Actions on angiotensins I and II.
Topics: Agaricales; Angiotensin I; Angiotensin II; Angiotensins | 1981 |
Fleischner Lecture. Metabolic functions of the lung and their clinical relevance.
Topics: Adult; Angiotensin I; Angiotensin II; Capillary Permeability; Female; Humans; Hypoxia; Infant, Newborn; Kallikreins; Kinins; Lung; Male; Renin-Angiotensin System; Respiratory Distress Syndrome, Newborn | 1982 |
Reflex and hormonal influences on cerebral control of water balance. Studies of alimentary and cardiovascular factors, and of systemic angiotensin in the regulation of water intake and ADH secretion.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Female; Goats; Hemorrhage; Rana temporaria; Reflex; Renin-Angiotensin System; Thirst; Vasopressins; Water; Water-Electrolyte Balance | 1982 |
A microassay for active and total renin concentration in human plasma based on antibody trapping.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Specimen Collection; Cattle; Female; Hydrogen-Ion Concentration; Kinetics; Male; Microchemistry; Pregnancy; Radioimmunoassay; Reference Standards; Renin; Sheep; Trypsin | 1980 |
Endogenous mechanisms that regulate prostacyclin release.
Topics: Angiotensin I; Angiotensin II; Animals; Aspirin; Biological Assay; Cats; Epoprostenol; Gas Chromatography-Mass Spectrometry; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Platelet Aggregation; Prostaglandins; Rabbits | 1980 |
Biological significance of active and inactive renin in man.
Topics: Adult; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension; Male; Renin; Saralasin | 1980 |
Plasma converting enzyme activity (C.E.A.): an index of plasma levels of captopril?
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Endopeptidases; Male; Proline; Rabbits | 1980 |
Angiotensin-induced release of prostacyclin from perfused organs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Captopril; Epoprostenol; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Mesenteric Arteries; Prostaglandins; Rabbits; Saralasin | 1980 |
Interrelation of the renin system and erythropoietin in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Erythropoietin; Female; Hypoxia; Male; Rats; Renin | 1980 |
Prostacyclin release and the modulation of some vasoactive hormones.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Cats; Cattle; Dogs; Epoprostenol; Female; Indomethacin; Kidney; Lung; Male; Prostaglandins; Rabbits | 1980 |
[An experimental study on the effects of the chronic administration of an angiotensin converting enzyme inhibitor (captopril) on blood pressure and the renin-angiotensin-aldosterone system (author's transl)].
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Captopril; Male; Proline; Rats; Renin | 1980 |
Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Captopril; Dogs; Epoprostenol; Female; Hemodynamics; Indomethacin; Kidney; Male; Proline; Prostaglandins; Regional Blood Flow | 1980 |
Separation and quantification of angiotensins and some related peptides by high-performance liquid chromatography.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Chromatography, High Pressure Liquid; Oligopeptides; Peptides; Rats; Renin | 1980 |
Effective use of captopril (angiotensin I-converting enzyme inhibitor) in severe childhood hypertension.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Child; Humans; Hypertension, Malignant; Proline; Renin | 1980 |
Evidence that the acute hypotensive effect of captopril in dogs is not wholly explained by a reduction of plasma angiotensin II and its direct vasoconstrictor effect.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Male; Proline; Renin; Sodium; Vasoconstriction | 1980 |
[DES-ASP1] Angiotensin II in the sheep: blood levels and its effect on plasma renin concentration.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Chromatography; Renin; Sheep; Sodium | 1980 |
Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood-Brain Barrier; Brain Chemistry; Dogs; In Vitro Techniques; Male; Rats; Renin | 1980 |
Angiotensin II in human cerebrospinal fluid may be an immunoassay artifact.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Male; Middle Aged; Radioimmunoassay; Renin | 1980 |
Suppression of captopril-induced increase in plasma renin activity by des-Asp1-,Ileu8-angiotensin II in man.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Blood Pressure; Captopril; Female; Humans; Hypertension; Isoleucine; Kinetics; Male; Middle Aged; Proline; Renin | 1981 |
Renin.
Topics: Angiotensin I; Angiotensin II; Humans; Hypertension; Kidney; Renin; Saralasin | 1981 |
Acute effects of captopril on blood pressure and circulating hormone levels in salt-replete and depleted normal subjects and essential hypertensive patients.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Bradykinin; Captopril; Diet, Sodium-Restricted; Epinephrine; Female; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Proline; Pulse; Renin; Sodium | 1981 |
Captopril attenuates adrenergic vasoconstriction in rat mesenteric arteries by angiotensin-dependent and -independent mechanisms.
Topics: Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Bradykinin; Captopril; Electric Stimulation; In Vitro Techniques; Male; Mesenteric Arteries; Norepinephrine; Potassium Chloride; Proline; Rats; Saralasin; Vasoconstriction | 1981 |
Angiotensin II's role in mediating angiotensin I- and tetradecapeptide-induced steroidogenesis by rat glomerulosa cells.
Topics: Adrenal Glands; Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Captopril; Female; In Vitro Techniques; Kinetics; Rats | 1981 |
Prostacyclin (PGI2) release accompanying angiotensin conversion in rat mesenteric vasculature.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Captopril; Epoprostenol; In Vitro Techniques; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; Prostaglandins; Rats; Saralasin | 1981 |
A human neutrophil-dependent pathway for generation of angiotensin II. Purification of the product and identification as angiotensin II.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Blood Proteins; Endopeptidases; Humans; Isoelectric Point; Neutrophils | 1981 |
Pharmacological evaluation in conscious dogs of factors involved in the renal vasodilator effect of captopril.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Female; Indomethacin; Kidney; Male; Proline; Renal Circulation; Saralasin; Vascular Resistance; Vasodilation | 1981 |
Use of captopril in the diagnosis of renal hypertension.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension, Renal; Male; Middle Aged; Proline; Renin | 1981 |
Effect of infused captopril on blood pressure and the renin-angiotensin-aldosterone system in normal dogs subjected to varying sodium balance.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Male; Proline; Renin-Angiotensin System; Vasoconstriction; Water-Electrolyte Balance | 1982 |
Renal tubular processing of small peptide hormones.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Transport; Bradykinin; Endocytosis; Gonadotropin-Releasing Hormone; Hormones; Hydrolysis; In Vitro Techniques; Kidney Tubules; Kidney Tubules, Proximal; Lysosomes; Microvilli; Molecular Weight; Peptides; Rabbits; Rats | 1982 |
Discrimination of renovascular from essential hypertension by converting enzyme inhibition with an orally active compound.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Captopril; Diagnosis, Differential; Female; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Aged; Proline; Renin | 1982 |
Captopril treatment: inter-dose variations in renin, angiotensins I and II, aldosterone and blood pressure.
Topics: Adolescent; Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Proline; Renin; Renin-Angiotensin System; Time Factors | 1982 |
Further studies on the role of angiotensin in the osmotic control of vasopressin release by the organ-cultured rat hypothalamo-neurohypophyseal system.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Captopril; Drug Synergism; Hypothalamo-Hypophyseal System; Male; Organ Culture Techniques; Osmosis; Rats; Saralasin; Sodium Chloride; Vasopressins | 1982 |
Vasopressor and depressor actions of angiotensin in the anesthetized fowl.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Chickens; Epinephrine; Female; Isoproterenol; Vasoconstriction; Vasodilation; Vasomotor System; Vasopressins | 1982 |
Effect of hypoxia on the conversion of angiotensin I to II in the isolated perfused rat lung.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Biotransformation; Female; Hypoxia; Lung; Male; Perfusion; Rats; Rats, Inbred Strains | 1982 |
Fast atom bombardment mass spectrometry of the angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Mass Spectrometry | 1982 |
Aminopeptidase A is angiotensinase A- I. Quantitative histochemical studies in the kidney glomerulus.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Densitometry; Glutamyl Aminopeptidase; Histocytochemistry; Kidney Glomerulus; Kinetics; Male; Mice; Rats; Rats, Inbred Strains | 1982 |
Influence of angiotensins (I, II & III) on prostaglandin production by minced rat renal medulla.
Topics: Alprostadil; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; In Vitro Techniques; Kidney Medulla; Male; Prostaglandins; Prostaglandins E; Rats; Rats, Inbred Strains; Thromboxane B2 | 1981 |
Loss of activity of angiotensin I and II in the perfused heart and kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; In Vitro Techniques; Kidney; Myocardium; Perfusion; Rats | 1980 |
Dipsogenesis in cold-acclimated rats.
Topics: Acclimatization; Angiotensin I; Angiotensin II; Animals; Cold Temperature; Drinking; Female; Isoproterenol; Rats; Saline Solution, Hypertonic; Serotonin; Temperature; Water Deprivation | 1981 |
Intrarenal vascular effects of angiotensin I and angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Dogs; Female; Functional Laterality; Kidney; Kidney Cortex; Male; Microspheres; Regional Blood Flow | 1981 |
Analysis of angiotensins I, II, III, and iodinated derivatives by high-performance liquid chromatography.
Topics: Acetonitriles; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Chromatography, High Pressure Liquid; Iodine Radioisotopes; Phosphates; Saralasin; Solvents | 1981 |
Effects of high oxygen tension on the metabolism of vasoactive hormones in isolated perfused rat lungs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Bradykinin; Lung; Male; Oxygen; Perfusion; Prostaglandins E; Pulmonary Circulation; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1981 |
Biological activity of des-Asp1-angiotensin I in man.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Blood Pressure; Humans; Male; Structure-Activity Relationship | 1980 |
Effect of acute hypoxia on the pulmonary conversion of angiotensin I to angiotensin II in dogs.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Carbon Dioxide; Cardiac Output; Dogs; Hydrogen-Ion Concentration; Hypoxia; Injections, Intravenous; Lung; Oxygen; Time Factors; Vasoconstriction | 1980 |
Angiotensin in the brain?
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain; Humans; Hypertension; Kidney; Rats; Receptors, Angiotensin; Renin; Stress, Physiological | 1980 |
Angiotensin I conversion and vascular reactivity in pathophysiological states in dogs.
Topics: Acid-Base Imbalance; Acidosis; Acidosis, Respiratory; Acute Disease; Alkalosis; Alkalosis, Respiratory; Angiotensin I; Angiotensin II; Angiotensins; Animals; Dogs; Hypoxia; Vascular Resistance | 1980 |
Effect of chronic treatment with estrogen on the dipsogenic response of rats to angiotensin.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Drinking; Estradiol; Female; Potassium; Rats; Sodium; Urination | 1980 |
Peripheral production of angiotensin II and III in sheep.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arteries; Sheep; Sodium; Veins | 1980 |
Laser raman spectroscopic analysis of angiotensin peptides' conformation.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Hydrogen Bonding; Protein Conformation; Saralasin; Spectrum Analysis, Raman; Tyrosine | 1980 |
Effect of nicotine on the metabolism of angiotensin I and II and prostaglandin E2 in isolated rat lungs.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; In Vitro Techniques; Lung; Male; Nicotine; Prostaglandins E; Rats; Smoking | 1980 |
Organ selective angiotensin antagonists: sarcosyl1-cysteinyl(S-methyl)8-angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Female; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Organ Specificity; Rabbits; Rats | 1980 |
Blood pressure responses of rats to angiotensin I and II after exposure to cigarette smoke.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Male; Oxygen; Rats; Smoking | 1980 |
Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Hypertension; Isoquinolines; Lung; Male; Rabbits; Rats; Rats, Inbred SHR; Tetrahydroisoquinolines; Time Factors | 1995 |
Effects of losartan on angiotensin and bradykinin peptides and angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Imidazoles; Losartan; Male; Organ Specificity; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Tetrazoles | 1995 |
In field-stimulated guinea-pig atria an AT1-receptor mediated increase of noradrenaline release by angiotensin II is seen only in the presence of prejunctional autoinhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Electric Stimulation; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Myocardium; Nerve Endings; Neuromuscular Junction; Norepinephrine; Receptors, Angiotensin; Refractory Period, Electrophysiological; Stimulation, Chemical; Sympathetic Nervous System | 1995 |
Pressor and reflex sensitivity is altered in spontaneously hypertensive rats treated with angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Peptide Fragments; Phenylephrine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reflex; Time Factors; Vasoconstrictor Agents | 1995 |
Angiotensin-(1-7) potentiates the hypotensive effect of bradykinin in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Indomethacin; Male; Peptide Fragments; Prostaglandins; Rats; Rats, Wistar; Renin-Angiotensin System; Vasoconstrictor Agents | 1995 |
Interaction of Phe8 of angiotensin II with Lys199 and His256 of AT1 receptor in agonist activation.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Line; Histidine; Inositol Phosphates; Lysine; Phenylalanine; Rats; Receptors, Angiotensin | 1995 |
Regulation of luminal alkalinization and acidification in the cortical collecting duct by angiotensin II.
Topics: Acids; Alkalies; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Biphenyl Compounds; Female; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Kidney Tubules, Collecting; Losartan; Osmolar Concentration; Perfusion; Rabbits; Tetrazoles | 1995 |
Metabolism of angiotensin I in isolated rat hearts. Effect of angiotensin converting enzyme inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Heart; In Vitro Techniques; Iodine Radioisotopes; Male; Myocardium; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar | 1995 |
Different effects of angiotensin-converting enzyme inhibition in human arteries and veins.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Bradykinin; Enalaprilat; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Losartan; Mammary Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Saphenous Vein; Tetrazoles | 1993 |
Phosphoramidon inhibits the conversion of big ET-1 into ET-1 in the pithed rat and in isolated perfused rat kidneys.
Topics: Angiotensin I; Angiotensin II; Animals; Aspartic Acid Endopeptidases; Blood Pressure; Decerebrate State; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Glycopeptides; Hemodynamics; In Vitro Techniques; Kidney; Male; Metalloendopeptidases; Norepinephrine; Protein Precursors; Rats; Rats, Sprague-Dawley; Rats, Wistar | 1993 |
Dual action of angiotensin II on coronary resistance in the isolated perfused rabbit heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelium, Vascular; Heart; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nitric Oxide Synthase; Oligopeptides; Organ Size; Quinolines; Rabbits; Receptors, Angiotensin; Vascular Resistance; Vasodilation | 1993 |
Is an intracellular renin-angiotensin system involved in control of cell communication in heart?
Topics: Angiotensin I; Angiotensin II; Animals; Cell Communication; Enalaprilat; In Vitro Techniques; Myocardium; Protein Kinase C; Rats; Renin-Angiotensin System | 1994 |
Vasoconstrictor responses after neo-intima formation and endothelial removal in the rabbit carotid artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin I; Angiotensin II; Animals; Arginine; Carotid Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Potassium Chloride; Prostaglandin Endoperoxides, Synthetic; Rabbits; Serotonin; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1994 |
Angiotensin-(1-7) and nitric oxide interaction in renovascular hypertension.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine; Biphenyl Compounds; Dogs; Hemodynamics; Hypertension, Renovascular; Imidazoles; Lisinopril; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Peptidyl-Dipeptidase A; Tetrazoles | 1995 |
Degradation of kinins, angiotensins and substance P by polymorphonuclear matrix metalloproteinases MMP 8 and MMP 9.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensins; Bradykinin; Chromatography, High Pressure Liquid; Collagenases; Hydrolysis; Kinetics; Kinins; Matrix Metalloproteinase 8; Matrix Metalloproteinase 9; Molecular Sequence Data; Peptide Fragments; Substance P; Substrate Specificity; Time Factors | 1994 |
Local angiotensin-converting enzyme inhibition blunts endothelin-1-induced increase in forearm vascular resistance.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Endothelins; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Middle Aged; Renin; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Human urinary kallikrein can generate angiotensin II from homologous renin substrates.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Kallikreins; Substrate Specificity | 1995 |
Renal pharmacology of GR138950, a novel non-peptide angiotensin AT1 receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzofurans; Captopril; Dogs; Female; Hemodynamics; Kidney; Kidney Function Tests; Male; Renal Agents; Renal Circulation; Urodynamics | 1995 |
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1995 |
Coronary kinin generation mediates nitric oxide release after angiotensin receptor stimulation.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Arginine; Coronary Vessels; Data Interpretation, Statistical; Dogs; In Vitro Techniques; Kinins; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Peptide Fragments; Receptors, Angiotensin; Stimulation, Chemical | 1995 |
Analysis of responses to angiotensin peptides in the hindquarters vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arachidonic Acid; Arginine; Blood Flow Velocity; Captopril; Cats; Dose-Response Relationship, Drug; Female; Hindlimb; Imidazoles; Male; Meclofenamic Acid; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Acid; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Pyridines; Regional Blood Flow; Tetrazoles; Thromboxane A2; Vasoconstrictor Agents | 1995 |
Direct effects of angiotensin I, angiotensin II, an ACE inhibitor and a serine proteinase inhibitor on cultured heart cells from spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Hypertension; Immunohistochemistry; Myocardium; Rats; Rats, Inbred SHR; Serine Proteinase Inhibitors; Uridine | 1995 |
Angiotensin I- and II- and norepinephrine-mediated pressor responses in an ancient holostean fish, the bowfin (Amia calva).
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; Fishes; Male; Norepinephrine; Phentolamine | 1995 |
Sympathetic nerve activity in conscious renal hypertensive rats treated with an angiotensin converting enzyme inhibitor or an angiotensin II antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Disease Models, Animal; Heart Rate; Hypertension, Renal; Imidazoles; Lisinopril; Losartan; Male; Nitroprusside; Rats; Rats, Wistar; Renin-Angiotensin System; Splanchnic Nerves; Sympathetic Nervous System; Tetrazoles | 1995 |
Antihypertensive actions of angiotensin-(1-7) in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diuresis; Heart Rate; Hypertension; Infusions, Intravenous; Male; Natriuresis; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Time Factors; Vasopressins | 1995 |
Angiotensin-(1-7) binding at angiotensin II receptors in the rat brain.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain; Cell Nucleus; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1995 |
Conversion and degradation of [125I] labelled angiotensin I in isolated perfused porcine coronary and carotid arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Carotid Arteries; Coronary Vessels; In Vitro Techniques; Iodine Radioisotopes; Models, Biological; Peptidyl-Dipeptidase A; Perfusion; Swine | 1995 |
Angiotensin II formation in the intact human heart. Predominance of the angiotensin-converting enzyme pathway.
Topics: Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Enalaprilat; Heart; Heart Transplantation; Humans; Iodine Radioisotopes; Kinetics; Models, Theoretical; Myocardium; Peptidyl-Dipeptidase A | 1995 |
[Renin synthesis by renal cells during chronic inhibition of angiotensin I converting enzyme].
Topics: Angiotensin I; Angiotensin II; Animals; Enalapril; Female; Kidney; Mice; Renin; Renin-Angiotensin System | 1994 |
Cardiac renin-angiotensin system: role in development of pressure-overload hypertrophy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Stenosis; Blood Pressure; Cardiomegaly; Disease Models, Animal; Heart Failure; Humans; Myocardial Contraction; Rats; Renin-Angiotensin System; Ventricular Function, Left | 1995 |
Effects of captopril on the human foetal placental circulation: an interaction with bradykinin and angiotensin I.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Placenta; Placental Function Tests; Pregnancy; Prostaglandins; Regional Blood Flow; Vasoconstriction | 1995 |
Inhibition by BMS 186295, a selective nonpeptide AT1 antagonist, of adrenal catecholamine release induced by angiotensin II in the dog in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Electrochemistry; Heart Rate; Irbesartan; Male; Tetrazoles | 1995 |
Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Captopril; Imidazoles; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptors, Angiotensin | 1995 |
Angiotensin-(1-7) and nitric oxide synthase in the hypothalamo-neurohypophysial system.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Animals; Cerebral Ventricles; Hypothalamo-Hypophyseal System; Immunohistochemistry; Male; NADP; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus | 1993 |
Differential responses to angiotensin-(1-7) in the feline mesenteric and hindquarters vascular beds.
Topics: Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arginine; Biphenyl Compounds; Cats; Hindlimb; Imidazoles; Losartan; Meclofenamic Acid; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Perfusion; Tetrazoles; Vascular Resistance; Vasoconstriction | 1993 |
Systemic and coronary effects of the angiotensin II receptor antagonist EXP3174 in dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Coronary Circulation; Dogs; Enalaprilat; Female; Furosemide; Hemodynamics; Imidazoles; Losartan; Male; Renin-Angiotensin System; Tetrazoles | 1993 |
Frequencies of the angiotensinogen gene and angiotensin I converting enzyme (ACE) gene polymorphisms in African Americans.
Topics: Alleles; Angiotensin I; Angiotensin II; Angiotensinogen; Black People; Gene Frequency; Genotype; Humans; Peptidyl-Dipeptidase A; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Renin-Angiotensin System | 1994 |
Effects of kidney transplantation on the renin-angiotensin systems of the recipients.
Topics: Acetylcholinesterase; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Disease Models, Animal; Hybridization, Genetic; Hypertension; Kidney; Kidney Transplantation; Male; Nephrectomy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 1994 |
Angiotensin II effects on second messengers involved in prolactin secretion are mediated by AT1 receptor in anterior pituitary cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; Cyclic AMP; Female; Inositol Phosphates; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; Receptors, Angiotensin; Second Messenger Systems; Tetradecanoylphorbol Acetate | 1994 |
On the plasticity of the cerebellar renin-angiotensin system: localization of components and effects of mechanical perturbation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cerebellum; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Situ Hybridization; Male; Microscopy, Confocal; Neuroglia; Neuronal Plasticity; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 1994 |
Effects of angiotensin II generated by an angiotensin converting enzyme-independent pathway on left ventricular performance in the conscious baboon.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Artifacts; Captopril; Chymases; Consciousness; Diastole; Dose-Response Relationship, Drug; Female; Hemodynamics; Infusions, Intra-Arterial; Male; Mast Cells; Papio; Peptidyl-Dipeptidase A; Serine Endopeptidases; Systole; Tissue Distribution; Ventricular Function, Left | 1995 |
Angiotensin(1-7) is an antagonist at the type 1 angiotensin II receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Rabbits; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Functional significance of angiotensin receptors in human myocardium. Significant differences between atrial and ventricular myocardium.
Topics: Angiotensin I; Angiotensin II; Atrial Function; Culture Techniques; Dose-Response Relationship, Drug; Heart Atria; Heart Ventricles; Hemodynamics; Humans; Myocardial Contraction; Prazosin; Propranolol; Receptors, Angiotensin; Saralasin; Ventricular Function | 1994 |
Angiotensin modulation of vascular tone and adrenergic neurotransmission in cat femoral arteries.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Cats; Endothelium, Vascular; Female; Femoral Artery; In Vitro Techniques; Male; Norepinephrine; Vasoconstriction | 1994 |
ACE inhibitors in heart failure. What dose?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Drug Administration Schedule; Heart Failure; Humans | 1995 |
Efficacy of intrarenal ACE-inhibition estimated from the renal response to angiotensin I and II in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Enalapril; Female; Humans; Infusions, Intravenous; Kidney; Male; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 1995 |
Photolabelling implicates an amino acid in the second transmembrane domain of the rat AT1A receptor in agonist binding.
Topics: Affinity Labels; Angiotensin I; Angiotensin II; Animals; Azides; Cell Line; Endopeptidases; GTP-Binding Proteins; Humans; Kidney; Molecular Weight; Peptide Fragments; Rats; Receptors, Angiotensin; Recombinant Proteins; Transfection | 1995 |
Characterization of protease-catalyzed hydrolysis of cyanine-labeled angiotensin using capillary electrophoresis with laser-induced fluorescence detection.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Carbocyanines; Carboxypeptidases; Cathepsin A; Electrophoresis; Endopeptidase K; Endopeptidases; Humans; Lasers; Molecular Sequence Data; Peptides; Serine Endopeptidases; Spectrometry, Fluorescence; Trypsin | 1995 |
Association between the natriuretic action of angiotensin-(1-7) and selective stimulation of renal prostaglandin I2 release.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Body Water; Electrolytes; Epoprostenol; Glomerular Filtration Rate; Indomethacin; Kidney; Male; Natriuresis; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance | 1995 |
Opposing actions of angiotensin-(1-7) and angiotensin II in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Brain; Female; Hypertension; Immune Sera; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 1995 |
Enhanced pressor response to angiotensin I in normotensive men with the deletion genotype (DD) for angiotensin-converting enzyme.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Base Sequence; Blood Pressure; Genotype; Humans; Male; Molecular Sequence Data; Peptidyl-Dipeptidase A; Renin | 1995 |
Ileoproctostomy is preferred over ileoanal pull-through in patients with indeterminate colitis.
Topics: Adult; Anastomosis, Surgical; Angiotensin I; Angiotensin II; Colectomy; Colitis; Colitis, Ulcerative; Colon; Crohn Disease; Elective Surgical Procedures; Female; Follow-Up Studies; Humans; Ileostomy; Intestinal Mucosa; Male; Proctocolectomy, Restorative; Rectum; Retrospective Studies; Treatment Outcome | 1995 |
Fos induced in brain of spontaneously hypertensive rats by angiotensin II and co-localization with AT-1 receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Hypertension; Hypothalamus; Immunohistochemistry; Phenylephrine; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Angiotensin; Saline Solution, Hypertonic; Solitary Nucleus | 1995 |
Prevention of angiotensin II induced myocyte necrosis and coronary vascular damage by lisinopril and losartan in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Coronary Vessels; Dose-Response Relationship, Drug; Heart; Hypertension, Renovascular; Imidazoles; Lisinopril; Losartan; Male; Necrosis; Rats; Rats, Sprague-Dawley; Tetrazoles | 1995 |
BMS-180560, an insurmountable inhibitor of angiotensin II-stimulated responses: comparison with losartan and EXP3174.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Extracellular Space; Imidazoles; In Vitro Techniques; Losartan; Male; Membranes; Muscle Contraction; Muscle, Smooth, Vascular; Phosphatidylinositols; Rabbits; Rats; Tetrazoles | 1994 |
Anti-hypertensive effect of oral controlled-release microspheres containing an ACE inhibitor (delapril hydrochloride) in rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Glycerides; Hydrogen-Ion Concentration; Indans; Male; Microspheres; Polymers; Rats; Rats, Sprague-Dawley; Solubility; Stearates | 1994 |
Hypotensive and natriuretic effects of RB 105, a new dual inhibitor of angiotensin converting enzyme and neutral endopeptidase in hypertensive rats.
Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Male; Natriuresis; Neprilysin; Rats; Rats, Inbred SHR; Rats, Wistar; Renin | 1995 |
Enhanced slow pressor effect of angiotensin II in two-kidney, one clip rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Water; Enalapril; Heart Rate; Hypertension, Renovascular; Male; Natriuresis; Rats; Rats, Sprague-Dawley | 1995 |
Angiotensin 1-7 has a biphasic effect on fluid absorption in the proximal straight tubule.
Topics: Adsorption; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bicarbonates; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Peptide Fragments; Perfusion; Permeability; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Tubular fluid concentrations and kidney contents of angiotensins I and II in anesthetized rats.
Topics: Angiotensin I; Angiotensin II; Animals; Kidney; Kidney Tubules, Proximal; Male; Punctures; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1994 |
[7-D-ALA]-angiotensin-(1-7): selective antagonism of angiotensin-(1-7) in the rat paraventricular nucleus.
Topics: Action Potentials; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Male; Neurons; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1994 |
Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors.
Topics: Adrenal Glands; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Female; Heart Rate; In Vitro Techniques; Injections, Intraventricular; Male; Medulla Oblongata; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Uterine Contraction | 1994 |
Evidence that angiotensin II is present in human monocytes.
Topics: Adult; Angiotensin I; Angiotensin II; Fluorescent Antibody Technique; Humans; Immunohistochemistry; In Vitro Techniques; Leukocytes, Mononuclear; Neutrophils; Radioimmunoassay | 1995 |
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Binding, Competitive; Biphenyl Compounds; Cell Division; Cells, Cultured; Coronary Vessels; DNA; DNA Primers; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression; Imidazoles; Kinetics; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Thymidine | 1995 |
Retrovirus-mediated transfer of an angiotensin type I receptor (AT1-R) antisense sequence decreases AT1-Rs and angiotensin II action in astroglial and neuronal cells in primary cultures from the brain.
Topics: Angiotensin I; Angiotensin II; Animals; Astrocytes; Base Sequence; Cells, Cultured; Gene Transfer Techniques; Genetic Vectors; Molecular Sequence Data; Neurons; Oligonucleotides, Antisense; Rats; Rats, Inbred WKY; Receptors, Angiotensin; Retroviridae | 1995 |
Plasma kinins increase after angiotensin-converting enzyme inhibition in human subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cross Reactions; Humans; Immune Sera; Isoquinolines; Kinins; Male; Peptidyl-Dipeptidase A; Quinapril; Radioimmunoassay; Renin; Sensitivity and Specificity; Tetrahydroisoquinolines | 1994 |
Angiotensin II stimulates tyrosine phosphorylation of the focal adhesion-associated protein paxillin in aortic smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Cell Adhesion Molecules; Cytoskeletal Proteins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Male; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Rats; Receptors, Angiotensin; Tyrosine | 1995 |
Species-related differences in inotropic effects of angiotensin II in mammalian ventricular muscle: receptors, subtypes and phosphoinositide hydrolysis.
Topics: Angiotensin I; Angiotensin II; Animals; Dogs; Ferrets; Heart; Heart Ventricles; In Vitro Techniques; Iodine Radioisotopes; Male; Myocardial Contraction; Myocardium; Phosphatidylinositols; Rabbits; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin; Species Specificity; Stimulation, Chemical | 1995 |
Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles | 1994 |
Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diuresis; Glomerular Filtration Rate; Imidazoles; Losartan; Male; Natriuresis; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1995 |
Local action of the renin angiotensin system in the porcine ophthalmic circulation: effects of ACE-inhibitors and angiotensin receptor antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Ciliary Body; Endothelium, Vascular; Eye; Microcirculation; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Regional Blood Flow; Renin-Angiotensin System; Swine; Vasodilation | 1995 |
Angiotensin-converting enzyme activity and contractile effects of angiotensin I and II in human uteroplacental arteries.
Topics: Angiotensin I; Angiotensin II; Arteries; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Myometrium; Peptidyl-Dipeptidase A; Placenta; Pregnancy | 1995 |
Plasma angiotensin(1-7) immunoreactivity is increased by salt load, water deprivation, and hemorrhage.
Topics: Angiotensin I; Angiotensin II; Animals; Hemorrhage; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Wistar; Sodium Chloride; Water Deprivation; Water-Electrolyte Imbalance | 1994 |
Characterization of contractile endothelin and angiotensin receptors in human resistance arteries: evidence for two endothelin and one angiotensin receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Azepines; Benzazepines; Bosentan; Endothelin Receptor Antagonists; Endothelins; Humans; In Vitro Techniques; Indoles; Mammary Arteries; Muscle Contraction; Plasmids; Receptors, Angiotensin; Receptors, Endothelin; Sulfonamides; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Viper Venoms | 1994 |
Increased expression of angiotensin peptides in the brain of transgenic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Cerebral Cortex; Female; Hypertension; Hypothalamus; Medulla Oblongata; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin | 1994 |
The origin of urinary angiotensins in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Enalapril; Female; Humans; Infusions, Intravenous; Kidney; Male; Peptidyl-Dipeptidase A; Radioimmunoassay; Sodium; Sodium, Dietary | 1994 |
Relative effects of alpha 1-adrenoceptor blockade, converting enzyme inhibitor therapy, and angiotensin II subtype 1 receptor blockade on ventricular remodeling in the dog.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; Hemodynamics; Magnetic Resonance Imaging; Myocardium; Phenylephrine; Ramipril; Receptors, Angiotensin; Renin; Stress, Mechanical; Ventricular Function | 1994 |
Analysis of responses to angiotensin IV in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Gas Analysis; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Male; Peptide Fragments; Pulmonary Circulation; Pyridines; Tetrazoles; Vascular Resistance | 1994 |
Natriuretic action of angiotensin(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Diuresis; Glomerular Filtration Rate; Kidney; Kidney Tubules; Male; Natriuresis; Peptide Fragments; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1994 |
Release of nitric oxide by angiotensin-(1-7) from porcine coronary endothelium: implications for a novel angiotensin receptor.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Arginine; Bradykinin; Coronary Vessels; Endothelium, Vascular; In Vitro Techniques; Isoquinolines; Molecular Sequence Data; Muscle Relaxation; Nitric Oxide; Nitroarginine; Peptide Fragments; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Vasodilator Agents | 1994 |
The deleterious effects of exogenous angiotensin I and angiotensin II on myocardial ischemia-reperfusion injury.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Circulation; Creatine Kinase; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred WKY; Renin-Angiotensin System | 1994 |
Comparison of pressor responses to angiotensin I, II, and III in pulmonary vascular bed of cats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Cats; Female; Imidazoles; Male; Pulmonary Circulation; Tetrazoles | 1994 |
Angiotensin I is converted to angiotensin II by a serine protease in human detrusor smooth muscle.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Enalaprilat; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle, Smooth; Peptidyl-Dipeptidase A; Serine Endopeptidases; Urinary Bladder | 1994 |
Angiotensins induce the release of prostacyclin from rabbit vas deferens: evidence for receptor heterogeneity.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Epoprostenol; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle, Smooth; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles; Vas Deferens | 1994 |
Increased urinary excretion of angiotensin during anaphylactoid reactions.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angiotensin I; Angiotensin II; Child; Child, Preschool; Drug Hypersensitivity; Female; Food Hypersensitivity; Humans; Male; Middle Aged; Renin-Angiotensin System | 1994 |
[Activity of the enzyme converting angiotensin I to angiotensin II (ACE) in patients with polycystic ovary syndrome].
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Hormones; Humans; Peptidyl-Dipeptidase A; Polycystic Ovary Syndrome; Spectrometry, Fluorescence | 1993 |
Myocardial beta-receptor and cardiac angiotensin alterations during the acute and chronic phases of viral myocarditis.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovirus Infections; Down-Regulation; Encephalomyocarditis virus; Female; Iodocyanopindolol; Mice; Mice, Inbred C3H; Myocarditis; Myocardium; Pindolol; Radioligand Assay; Receptors, Adrenergic, beta; Up-Regulation | 1994 |
Calcium dependency of the AT1-receptor mediated effects in the rat portal vein: influence of calcium antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium; Calcium Channel Blockers; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Rats; Rats, Wistar; Receptors, Angiotensin | 1994 |
Expression of angiotensin-converting enzyme in human placenta and its physiologic role in the fetal circulation.
Topics: Angiotensin I; Angiotensin II; Blotting, Northern; Female; Fetus; Gene Expression; Humans; Peptidyl-Dipeptidase A; Placenta; Pregnancy; RNA, Messenger | 1994 |
AT1 receptor characteristics of angiotensin analogue binding in human synovium.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Arthritis, Rheumatoid; Autoradiography; Biphenyl Compounds; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Imidazoles; Immunohistochemistry; In Vitro Techniques; Iodine Radioisotopes; Ligands; Losartan; Male; Middle Aged; Osteoarthritis; Pyridines; Receptors, Angiotensin; Synovial Fluid; Tetrazoles | 1994 |
Vasoconstrictor responses to components of the renin-angiotensin system in cyclosporin-induced hypertension in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Cyclosporine; Female; Hypertension; In Vitro Techniques; Mesenteric Arteries; Rats; Rats, Wistar; Renin-Angiotensin System; Sensitivity and Specificity; Vascular Resistance; Vasoconstriction | 1994 |
Novel central action of des-Asp-angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Hypothalamus; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1994 |
Effects of angiotensin II and angiotensin-(1-7) on the release of [3H]norepinephrine from rat atria.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Drug Interactions; Electric Stimulation; Female; Heart; Heart Atria; Imidazoles; Losartan; Myocardium; Norepinephrine; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles | 1994 |
Converting enzyme inhibition and renal tissue angiotensin II in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Enalapril; Kidney; Male; Radioimmunoassay; Ramipril; Rats; Rats, Sprague-Dawley | 1994 |
Positive inotropic action of angiotensin II in the pithed rat.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Myocardial Contraction; Pyridines; Rats; Rats, Wistar; Stimulation, Chemical; Tetrazoles | 1993 |
The pharmacological characterization of FK 739, a new angiotensin II-receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bronchial Diseases; Cattle; Cell Membrane; Cerebellum; Dogs; Edema; Guinea Pigs; Hypertension; Hypertension, Renovascular; Imidazoles; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pyridines; Rabbits; Rats; Rats, Inbred SHR; Rats, Wistar | 1993 |
Pulmonary hypertension as a fatal complication of extrahepatic portal hypertension.
Topics: Angiotensin I; Angiotensin II; Child; Dinoprost; Fatal Outcome; Female; Humans; Hypertension, Portal; Hypertension, Pulmonary; Thromboxane B2 | 1993 |
Angiotensin levels in the eye.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Animals; Blood-Retinal Barrier; Child; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Eye; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Peptidyl-Dipeptidase A; Rabbits; Renin-Angiotensin System; Swine | 1994 |
The renin-angiotensin system in the type II diabetic obese Zucker rat.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; In Vitro Techniques; Male; Norepinephrine; Obesity; Rats; Rats, Zucker; Renin; Renin-Angiotensin System; Vasoconstriction | 1993 |
Role of angiotensin AT1 receptor in the cardiovascular response to footshock.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Electroshock; Heart Rate; Hemodynamics; Imidazoles; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1994 |
Direct evidence for erythropoietin-induced release of endothelin from peripheral vascular tissue.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Endothelins; Erythropoietin; Hindlimb; Humans; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Thromboxane B2 | 1994 |
Cardiac renin is kidney-derived.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Myocardium; Nephrectomy; Renin; Swine; Tissue Distribution | 1993 |
Renin-angiotensin system in neonatal rats: induction of a renal abnormality in response to ACE inhibition or angiotensin II antagonism.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Pressure; Body Fluids; Body Weight; Electrolytes; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Renin-Angiotensin System | 1994 |
Analysis of angiotensins I, II, and III in pulmonary vascular bed of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Blood Vessels; Captopril; Enalaprilat; Imidazoles; In Vitro Techniques; Losartan; Male; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tetrazoles | 1994 |
Cardiovascular effects produced by micro-injection of angiotensin-(1-7) on vasopressor and vasodepressor sites of the ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Organ Specificity; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 1993 |
Selective changes in angiotensin II AT1 and AT2 receptor subtypes in the rat superior colliculus following eye enucleation.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Eye Enucleation; Geniculate Bodies; Imidazoles; Iodine Radioisotopes; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Retina; Saralasin; Subcellular Fractions; Superior Colliculi; Suprachiasmatic Nucleus; Synapses; Tetrazoles; Visual Pathways | 1994 |
TCV-116, a newly developed angiotensin II receptor antagonist, induces regression of cardiac hypertrophy through suppression of the tissue renin-angiotensin system in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Heart Atria; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Male; Organ Size; Rats; Rats, Inbred SHR; Renin; Tetrazoles | 1994 |
Effects of LTD4 and its specific antagonist L-660,711 in isolated rat hearts with chronic myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Animals; Body Weight; Bronchodilator Agents; Coronary Circulation; Heart; Heart Rate; In Vitro Techniques; Leukotriene D4; Male; Myocardial Infarction; Organ Size; Propionates; Quinolines; Rats; Rats, Wistar; Time Factors; Ventricular Function, Left | 1994 |
Angiotensin II overflow from canine skeletal muscle in vivo: importance of plasma angiotensin I.
Topics: Angiotensin I; Angiotensin II; Animals; Dogs; Electric Stimulation; Female; Isoproterenol; Kinetics; Muscles; Oligopeptides; Propranolol; Renin; Sympathetic Nervous System; Time Factors; Vasodilation | 1994 |
Vascular renin in the guinea pig. Suppression by the renin inhibitor remikiren.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Captopril; Chromatography, High Pressure Liquid; Guinea Pigs; Hindlimb; Imidazoles; Male; Radioimmunoassay; Renin | 1994 |
Peptide dot immunoassay and immunoblotting: electroblotting from aluminum thin-layer chromatography plates and isoelectric focusing gels to activated nitrocellulose.
Topics: Acquired Immunodeficiency Syndrome; Aluminum; Amino Acid Sequence; Angiotensin I; Angiotensin II; Antigens, Viral; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Collodion; HIV-1; HIV-2; Humans; Immunoassay; Immunoblotting; Isoelectric Focusing; Molecular Sequence Data; Peptide Fragments; Proteins; Viral Proteins | 1993 |
Etiology of the sexual dimorphism in renal peripheral benzodiazepine receptor response to stress in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arousal; Circadian Rhythm; Escape Reaction; Fear; Female; Glucocorticoids; Gonadal Steroid Hormones; Kidney; Male; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Renin; Sex Characteristics | 1993 |
Long-term low-dose angiotensin converting enzyme inhibitor treatment increases vascular cyclic guanosine 3',5'-monophosphate.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Bradykinin; Cyclic GMP; Dose-Response Relationship, Drug; Female; Hypertension; In Vitro Techniques; Indoles; Maternal-Fetal Exchange; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Perindopril; Pregnancy; Ramipril; Rats; Rats, Inbred SHR; Reference Values; Systole | 1993 |
Angiotensin II increases norepinephrine release from atria by acting on angiotensin subtype 1 receptors.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Male; Myocardium; Norepinephrine; Ramipril; Receptors, Angiotensin; Tetrazoles | 1993 |
Dose-response differences in the ability of ramipril to improve retention in diabetic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Avoidance Learning; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male; Mice; Ramipril; Retention, Psychology | 1993 |
[The changes in the levels of angiotensins and angiotensin converting enzyme and effects of captopril in patients with hypoxic pulmonary hypertension].
Topics: Aged; Angiotensin I; Angiotensin II; Captopril; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Peptidyl-Dipeptidase A | 1993 |
Comparative effects of angiotensin-(1-7) and angiotensin II on piglet pial arterioles.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Arterioles; Cerebral Arteries; Female; Indomethacin; Male; Peptide Fragments; Pia Mater; Prostaglandins; Swine; Vasodilator Agents | 1993 |
Renal tissue angiotensin II: response to infusions of angiotensin I and an angiotensin-converting enzyme inhibitor.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chromatography, High Pressure Liquid; Infusions, Parenteral; Kidney; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Reproducibility of Results | 1993 |
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Cytoplasmic Granules; Endothelins; Gene Expression Regulation; Genes, fos; Hypertrophy; In Vitro Techniques; Mechanoreceptors; Myocardium; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger; Stress, Mechanical | 1993 |
Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Hindlimb; Hypertension; Male; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 1993 |
Rapid reversal of angiotensin I-induced contractions in rat carotid arteries after acute and chronic treatment with the angiotensin-converting enzyme inhibitor, 3-[(5-amino-1-carboxy-1S-pentyl)amino]2,3,4,5-tetrahydro-2-oxo- 3S-1H-1-benzazepena-1-acetic a
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Carbon Radioisotopes; Carotid Arteries; Drug Interactions; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Tissue Distribution | 1993 |
Modulation of phospholipase A2 activity and sodium transport by angiotensin-(1-7).
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin I; Angiotensin II; Animals; Biological Transport; Cells, Cultured; Kidney Tubules, Proximal; Lysophosphatidylcholines; Male; Peptide Fragments; Phospholipases A; Phospholipases A2; Rabbits; Sodium | 1993 |
Plasma concentrations of arginine vasopressin, oxytocin and angiotensin in patients with hymenoptera venom anaphylaxis.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine Vasopressin; Arthropod Venoms; Child; Chromatography, High Pressure Liquid; Female; Humans; Hymenoptera; Male; Middle Aged; Oxytocin; Radioimmunoassay | 1993 |
Effects of a metalloendopeptidase-24.15. Inhibitor on renal hemodynamics and function in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Binding Sites; Blood Pressure; Bradykinin; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; Metalloendopeptidases; Oligopeptides; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Renal Circulation; Urination | 1994 |
Oxytocic effect of trypsin on the isolated rat uterus.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Enalaprilat; Female; Imidazoles; In Vitro Techniques; Isometric Contraction; Losartan; Oxytocin; Pepstatins; Rats; Saralasin; Tetrazoles; Trypsin; Uterine Contraction; Uterus | 1994 |
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles | 1994 |
Human leukocytes contain angiotensin I, angiotensin II and angiotensin metabolites.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angiotensin I; Angiotensin II; Animals; Arthropod Venoms; Chromatography, High Pressure Liquid; Female; Humans; Hymenoptera; Leukocytes; Male; Middle Aged; Radioimmunoassay | 1994 |
[Effect of hypoxia on the conversion of angiotensin I to A II in pulmonary vascular endothelial cells].
Topics: Angiotensin I; Angiotensin II; Animals; Cell Hypoxia; Cells, Cultured; Endothelium, Vascular; Pulmonary Artery; Rats; Rats, Wistar | 1993 |
Comparison of the effects of EXP3174, an angiotensin II antagonist and enalaprilat on myocardial infarct size in anaesthetized dogs.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Disease Models, Animal; Dogs; Enalaprilat; Female; Furosemide; Heart Rate; Imidazoles; Injections, Intravenous; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Renin-Angiotensin System; Tetrazoles | 1993 |
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst | 1993 |
New angiotensin I isolated from a reptile, Alligator mississippiensis.
Topics: Alligators and Crocodiles; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Coturnix; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Species Specificity | 1993 |
Localization of angiotensin peptide-forming enzymes of 3T3-F442A adipocytes.
Topics: 3T3 Cells; Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Base Sequence; Blotting, Northern; Glycerolphosphate Dehydrogenase; Mice; Molecular Sequence Data; Oligonucleotide Probes; Polymerase Chain Reaction; Renin; RNA, Messenger; Tissue Distribution | 1993 |
Prevention of genetic hypertension by early treatment of spontaneously hypertensive rats with the angiotensin converting enzyme inhibitor captopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Hypertension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Inbred SHR | 1993 |
Marked species-difference in the vascular angiotensin II-forming pathways: humans versus rodents.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Animals; Arteries; Captopril; Female; Humans; In Vitro Techniques; Male; Middle Aged; Oligopeptides; Rabbits; Rats; Rats, Wistar; Serine Endopeptidases; Species Specificity | 1993 |
Nonpeptide angiotensin II receptor antagonists: potential advantages over ACE inhibitors.
Topics: Acrylates; Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cough; Dogs; Enalapril; Female; Glomerular Filtration Rate; Imidazoles; Male; Renal Circulation; Thiophenes | 1993 |
Effects of the blockade of the renin-angiotensin system in cyclosporin-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Cilazapril; Cyclosporine; Female; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Male; Renin; Renin-Angiotensin System; Saimiri | 1993 |
Arteriolar constriction and local renin-angiotensin system in rat microcirculation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arterioles; In Vitro Techniques; Male; Microcirculation; Muscle, Smooth, Vascular; Muscles; Nephrectomy; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasoconstriction | 1993 |
Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dipeptides; Enalaprilat; Hypertrophy, Left Ventricular; Iodine Radioisotopes; Male; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Up-Regulation; Ventricular Function, Left | 1993 |
Indirect evidence for vascular uptake of circulating renin in hypertensive patients.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Vessels; Female; Forearm; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Male; Middle Aged; Receptors, Adrenergic, beta; Regional Blood Flow; Renin; Renin-Angiotensin System | 1993 |
Measurement of angiotensin I converting enzyme inhibition in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Captopril; Cricetinae; Dipeptides; Enalaprilat; Humans; Isoquinolines; Lisinopril; Male; Mesocricetus; Papillary Muscles; Tetrahydroisoquinolines | 1993 |
Responses to angiotensin with and without angiotensin-converting enzyme inhibition in the canine left anterior descending coronary artery.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Circulation; Coronary Vessels; Dogs; Enalaprilat | 1993 |
Angiotensin I and II exert inotropic effects in atrial but not in ventricular human myocardium. An in vitro study under physiological experimental conditions.
Topics: Aged; Angiotensin I; Angiotensin II; Child, Preschool; Female; Heart Atria; Heart Ventricles; Humans; In Vitro Techniques; Infant; Male; Middle Aged; Myocardial Contraction; Myocardium; Peptidyl-Dipeptidase A; Receptors, Angiotensin; Renin-Angiotensin System; Stimulation, Chemical | 1993 |
Complete primary structure and biochemical properties of gilatoxin, a serine protease with kallikrein-like and angiotensin-degrading activities.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Coagulation Factors; Female; Humans; Kallikreins; Lizards; Male; Mice; Molecular Sequence Data; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sequence Homology, Amino Acid; Serine Endopeptidases; Venoms | 1993 |
Response of the human urinary bladder to angiotensins: a comparison between neurogenic and control bladders.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Urinary Bladder; Urinary Bladder, Neurogenic | 1993 |
Regional angiotensin II production in essential hypertension and renal artery stenosis.
Topics: Adult; Angiotensin I; Angiotensin II; Arteries; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Renal Artery Obstruction; Tissue Distribution; Veins | 1993 |
Effect of nonpeptide angiotensin AT-1 and AT-2 antagonists on isoproterenol-induced renin release.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Injections, Intraventricular; Isoproterenol; Losartan; Male; Potassium; Pyridines; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1993 |
Functional role of brain AT1 and AT2 receptors in the central angiotensin II pressor response.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Brain; Chlorisondamine; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1993 |
Regulation of vascular angiotensin release.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aorta; Base Sequence; Biphenyl Compounds; Dexamethasone; Ethinyl Estradiol; Hindlimb; Imidazoles; Losartan; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Muscles; Nephrectomy; Oligodeoxyribonucleotides; Perfusion; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles; Triiodothyronine | 1993 |
Binding and signal transduction of the cloned vascular angiotensin II (AT1a) receptor cDNA stably expressed in Chinese hamster ovary cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adenylyl Cyclases; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Biphenyl Compounds; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA; Imidazoles; Losartan; Pyridines; Radioligand Assay; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Transfection | 1993 |
Degradation of angiotensin I in the endothelium and smooth muscle of the rat aorta.
Topics: Amino Acid Sequence; Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Anti-Bacterial Agents; Aorta; Endothelium, Vascular; Leucine; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Peptides; Rats; Rats, Sprague-Dawley | 1993 |
Role of angiotensin AT1 and AT2 receptors in mediating the renal effects of angiotensin II in the anaesthetized dog.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dogs; Female; Glomerular Filtration Rate; Imidazoles; Kidney; Kidney Function Tests; Male; Nicotinic Acids; Pyridines; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1993 |
Simplified method for quantitation of angiotensin peptides in tissue.
Topics: Angiotensin I; Angiotensin II; Animals; Brain Stem; Chromatography, High Pressure Liquid; Hypothalamus; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley | 1993 |
Tissue renin: focus on vascular angiotensin formation.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Male; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Renin | 1993 |
Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Vessels; Captopril; Hindlimb; In Vitro Techniques; Male; Perfusion; Rats; Rats, Sprague-Dawley | 1993 |
Alterations in prostaglandin production in spontaneously hypertensive rat smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Dinoprostone; Epoprostenol; Hypertension; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 1993 |
Angiotensin blockade and the progression of renal damage in the spontaneously hypertensive rat.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Chromatography, High Pressure Liquid; Hydralazine; Hypertension; Indans; Kidney; Male; Proteinuria; Rats; Rats, Inbred SHR; Survival Analysis; Tetrazoles | 1993 |
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Dipeptides; Humans; Imidazoles; Losartan; Male; Mice; Mice, Transgenic; Morpholines; Recombinant Proteins; Renin; Renin-Angiotensin System; Tetrazoles | 1993 |
Responses of the bovine mammary artery to angiotensins.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Arteries; Captopril; Cattle; Female; Mammary Glands, Animal | 1993 |
Effects of ACE inhibitors on circulating versus cardiac angiotensin II in volume overload-induced cardiac hypertrophy in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Hypertrophy, Left Ventricular; Isoquinolines; Male; Myocardium; Quinapril; Rats; Rats, Wistar; Tetrahydroisoquinolines; Ventricular Pressure | 1995 |
Angiotensin and bradykinin metabolism by peptidases identified in skeletal muscle.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Bradykinin; In Vitro Techniques; Methionyl Aminopeptidases; Muscle, Skeletal; Neprilysin; Peptide Hydrolases; Peptidyl-Dipeptidase A; Rabbits | 1995 |
Angiotensin II-forming activity in a reconstructed ancestral chymase.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensins; Animals; Binding Sites; Chymases; Evolution, Molecular; Genes, Synthetic; Humans; Molecular Sequence Data; Rats; Serine Endopeptidases; Substrate Specificity | 1996 |
Bradykinin B2 receptor-mediated chronotropic effect of bradykinin in isolated guinea pig atria.
Topics: Adrenergic beta-Agonists; Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Function; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Enzyme Inhibitors; Guinea Pigs; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Kallidin; Male; Myocardium; Nitric Oxide; Prostaglandins; Receptor, Bradykinin B2; Receptors, Bradykinin; Sensitivity and Specificity | 1995 |
Activation of angiotensin-generating systems in the developing rat kidney.
Topics: Aging; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Female; Gene Expression; Humans; Kidney; Male; Peptidyl-Dipeptidase A; Pregnancy; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1996 |
Role of dopamine in the striatum, renin-angiotensin system and renal sympathetic nerve on the development of two-kidney, one-clip Goldblatt hypertension.
Topics: 3,4-Dihydroxyphenylacetic Acid; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Corpus Striatum; Dopamine; Homovanillic Acid; Hypertension, Renovascular; Kidney; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sympathetic Nervous System | 1996 |
Converting enzyme inhibition and its withdrawal in spontaneously hypertensive rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Indoles; Male; Peptide Fragments; Perindopril; Radioimmunoassay; Rats; Rats, Inbred SHR; Renin; Tissue Distribution | 1995 |
Characterization of contractile response to angiotensin in epididymal rat vas deferens.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth; Oligopeptides; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Vas Deferens; Vasoconstrictor Agents | 1995 |
Effects of dietary salt on angiotensin peptides in kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Chromatography, High Pressure Liquid; Diet, Sodium-Restricted; Drug Resistance; Kidney; Male; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Sodium Chloride | 1995 |
Angiotensin II and angiotensin-(1-7) effects on free cytosolic sodium, intracellular pH, and the Na(+)-H+ antiporter in vascular smooth muscle.
Topics: Amiloride; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cytosol; Hydrogen-Ion Concentration; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Ouabain; Peptide Fragments; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Hydrogen Exchangers | 1996 |
Structure and effects of a kinin potentiating fraction F (AppF) isolated from Agkistrodon piscivorus piscivorus venom.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Crotalid Venoms; Drug Synergism; Guinea Pigs; Mass Spectrometry; Muscle, Smooth; Oligopeptides; Peptide Fragments; Rats | 1995 |
Activation of p70 S6 protein kinase is necessary for angiotensin II-induced hypertrophy in neonatal rat cardiac myocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Cells, Cultured; Enzyme Activation; Gene Expression; Genes, fos; Immunosuppressive Agents; Myocardium; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; Sirolimus | 1996 |
Metabolism of angiotensins by head membranes of the leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Cell Membrane; Endopeptidases; Head; Helminth Proteins; Kinetics; Leeches; Membrane Proteins; Molecular Sequence Data; Neprilysin; Protease Inhibitors; Substrate Specificity | 1996 |
Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Vessels; Dogs; Kinins; Male; Nitric Oxide; Peptide Fragments; Receptors, Angiotensin; Vasodilation | 1996 |
Evidence for a physiological role of angiotensin-(1-7) in the control of hydroelectrolyte balance.
Topics: Angiotensin I; Angiotensin II; Animals; Male; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System; Water-Electrolyte Balance | 1996 |
The association of thirst, sodium appetite and vasopressin release with c-fos expression in the forebrain of the rat after intracerebroventricular injection of angiotensin II, angiotensin-(1-7) or carbachol.
Topics: Angiotensin I; Angiotensin II; Animals; Appetite; Carbachol; Drinking Behavior; Injections, Intraventricular; Male; Peptide Fragments; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred Strains; Sodium; Thirst; Vasopressins | 1995 |
C-type natriuretic peptide. An endogenous inhibitor of vascular angiotensin-converting enzyme activity.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Forearm; Humans; Natriuretic Peptide, C-Type; Proteins; Regional Blood Flow; Vasoconstriction | 1996 |
Involvement of neurohumoral factors in the pressor mechanism of NG-nitro-L-arginine.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Captopril; Dogs; Female; Hexamethonium; Male; Nitroarginine; Phentolamine; Phenylephrine; Vasoconstrictor Agents | 1995 |
Angiotensin-(1-7) inhibits vascular smooth muscle cell growth.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Cattle; Cell Count; Cell Division; Cells, Cultured; Data Interpretation, Statistical; Male; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Receptors, Angiotensin; Thymidine | 1996 |
Ability of angiotensin II to modulate striatal dopamine release via the AT1 receptor in vitro and in vivo.
Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Corpus Striatum; Dopamine; Extracellular Space; Female; Imidazoles; In Vitro Techniques; Losartan; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1996 |
Isolation of a renin-like enzyme from the leech Theromyzon tessulatum.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; Binding Sites; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Leeches; Molecular Sequence Data; Molecular Weight; Peptides; Rats; Renin; Substrate Specificity; Swine; Temperature | 1995 |
Angiotensin and bradykinin metabolism by peptidases identified in cultured human skeletal muscle myocytes and fibroblasts.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Bradykinin; Cells, Cultured; Endopeptidases; Fibroblasts; Humans; Methionyl Aminopeptidases; Muscle, Skeletal; Neprilysin; Peptidyl-Dipeptidase A | 1995 |
Comparison of ANG II with other growth factors on Egr-1 and matrix gene expression in cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Extracellular Matrix Proteins; Fibroblasts; Gene Expression; Growth Substances; Heart; Immediate-Early Proteins; Myocardium; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger; Transcription Factors | 1996 |
Renal actions of angiotensin-(1-7): in vivo and in vitro studies.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Hemodynamics; Kidney; Kidney Tubules, Proximal; Male; Nystatin; Osmolar Concentration; Ouabain; Oxygen Consumption; Peptide Fragments; Rats; Rats, Wistar; Renal Circulation; Sodium-Potassium-Exchanging ATPase | 1996 |
Angiotensin II formation in dog heart is mediated by different pathways in vivo and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Dogs; Hemodynamics; In Vitro Techniques; Male; Myocardium | 1996 |
Peripheral artery structure and endothelial function in heart failure: effect of ACE inhibition.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output, Low; Endothelium, Vascular; Femoral Artery; Hemodynamics; In Vitro Techniques; Indoles; Male; Myocardial Infarction; Nitroprusside; Perindopril; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
Down-regulation of angiotensin AT1 receptor by progesterone in human placenta.
Topics: Angiotensin I; Angiotensin II; Chloroquine; Down-Regulation; Female; Humans; Placenta; Pregnancy; Progesterone; Receptors, Angiotensin; Trophoblasts | 1996 |
In situ production of angiotensin II by fibrosed rat pericardium.
Topics: Angiotensin I; Angiotensin II; Animals; Fibrosis; In Vitro Techniques; Male; Myocardium; Peptidyl-Dipeptidase A; Pericardium; Rats; Rats, Sprague-Dawley; Reference Values | 1996 |
The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cognition; Imidazoles; Losartan; Oligopeptides; Rats; Receptors, Angiotensin; Tetrazoles | 1996 |
Angiotensin peptide research overlooked.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Chromatography, High Pressure Liquid; Humans; Radioimmunoassay; Solvents | 1996 |
Angiotensin type 1 receptor antagonists CV-11974 and EXP 3174 cause selective renal vasodilatation in conscious spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Tetrazoles; Vasodilation | 1996 |
A novel action of angiotensin peptides in inhibiting neurite outgrowth from isolated chick sympathetic neurons in culture.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cells, Cultured; Chick Embryo; Imidazoles; Neurites; Neuropeptides; Pyridines; Sympathetic Nervous System; Tissue Fixation | 1996 |
Comparative studies of the angiogenic activity of vasoactive intestinal peptide, endothelins-1 and -3 and angiotensin II in a rat sponge model.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Endothelins; Male; Neovascularization, Pathologic; Rats; Rats, Wistar; Receptors, Vasoactive Intestinal Peptide; Vasoactive Intestinal Peptide; Vasoconstrictor Agents; Xenon Radioisotopes | 1996 |
Identification of nonconserved amino acids in the AT1 receptor which comprise a general binding site for biphenylimidazole antagonists.
Topics: Amino Acid Sequence; Amino Acids; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anura; Binding Sites; Binding, Competitive; Biphenyl Compounds; COS Cells; Imidazoles; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Rats; Receptors, Angiotensin | 1996 |
Renin-angiotensin system in stretch-induced hypertrophy of cultured neonatal rat heart cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Cardiomegaly; Cells, Cultured; Heart; Imidazoles; Losartan; Muscle Proteins; Muscle Spindles; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 1996 |
Potentiation of purinergic transmission by angiotensin in prostatic rat vas deferens.
Topics: Adrenergic Uptake Inhibitors; Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Norepinephrine; Oligopeptides; Prostate; Protease Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reserpine; Synaptic Transmission; Tetrazoles; Vas Deferens | 1996 |
Electrophysiological properties of paraventricular magnocellular neurons in rat brain slices: modulation of IA by angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Electrophysiology; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1996 |
The urinary bladder angiotensin system: response to infusions of angiotensin I and angiotensin-converting enzyme inhibitors.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Enalaprilat; Male; Ramipril; Rats; Rats, Sprague-Dawley; Urinary Bladder | 1996 |
Development of [11C]L-159,884: a radiolabelled, nonpeptide angiotensin II antagonist that is useful for angiotensin II, AT1 receptor imaging.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Hydrocarbons, Iodinated; Image Processing, Computer-Assisted; Imidazoles; Isotope Labeling; Pyridines; Receptors, Angiotensin; Tomography, Emission-Computed | 1996 |
Enhanced renal sensitivity to angiotensin actions in diabetes mellitus in the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Injections, Intra-Arterial; Injections, Intravenous; Kidney; Male; Rats; Rats, Inbred Strains; Renal Circulation | 1996 |
Effect of acute volume expansion associated with salt load on the profile of plasma angiotensins in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Arginine Vasopressin; Male; Peptide Fragments; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride; Water-Electrolyte Balance | 1996 |
Pressor action of angiotensin I at the ventrolateral medulla: effect of selective angiotensin blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Ramipril; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1996 |
Enhanced angiotensin receptor type 1 mRNA degradation and induction of polyribosomal mRNA binding proteins by angiotensin II in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Autoradiography; Cells, Cultured; Cycloheximide; Drug Stability; Muscle, Smooth, Vascular; Polyribosomes; Rats; Receptors, Angiotensin; RNA-Binding Proteins; RNA, Messenger; RNA, Ribosomal; Stimulation, Chemical; Subcellular Fractions | 1996 |
Evidence for the existence of a functional cardiac renin-angiotensin system in humans.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Chromatography, High Pressure Liquid; Coronary Circulation; Diet, Sodium-Restricted; Female; Humans; Male; Middle Aged; Myocardium; Peptide Fragments; Renin-Angiotensin System; Tissue Distribution | 1996 |
Analysis of responses to angiotensin I and angiotensin I-(3-10) in the mesenteric vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Cats; Dose-Response Relationship, Drug; Female; Male; Splanchnic Circulation | 1996 |
Effects of angiotensin-converting enzyme inhibition on arterial, venous and capillary functions in cat skeletal muscle in vivo.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Capillaries; Cats; Enalaprilat; Male; Muscle Tonus; Muscle, Skeletal; Muscle, Smooth, Vascular; Regional Blood Flow; Sympathectomy; Vascular Resistance | 1996 |
Effects of angiotensin I and angiotensin II in blood vessels: greater influence of converting enzyme activity in the rabbit basilar artery.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Basilar Artery; Captopril; Carotid Arteries; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rabbits; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 1996 |
Excess extrafetal fluid without demonstrable changes in placental concentration gradients after week-long infusions of angiotensin into fetal lambs.
Topics: Angiotensin I; Angiotensin II; Animals; Bicarbonates; Body Water; Chlorides; Female; Fetus; Glucose; Osmolar Concentration; Placenta; Polyhydramnios; Potassium; Pregnancy; Sheep; Sodium; Urea | 1995 |
Modulation by locally produced luminal angiotensin II of proximal tubular sodium reabsorption via an AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Imidazoles; Kidney Tubules, Proximal; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sodium; Tetrazoles | 1996 |
Cyclical changes in the renin-angiotensin-aldosterone system during the menstrual cycle of the baboon (Papio hamadryas).
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Electrolytes; Enalapril; Female; Lactation; Male; Menstrual Cycle; Papio; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1996 |
Valvular interstitial cells express angiotensinogen and cathepsin D, and generate angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; Cathepsin D; Cells, Cultured; Dexamethasone; Enzyme Inhibitors; Gene Expression; Haloperidol; Heart Valves; Lisinopril; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1996 |
Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Pressure; Captopril; Epoprostenol; Humans; Hypertension; Peptide Fragments | 1996 |
Angiotensin II, via an action at AT1 receptors, may modulate the behavioural effects of ET-1 in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Biphenyl Compounds; Drug Synergism; Endothelin-1; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
Angiotensin II stimulates sperm motility.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Male; Microscopy, Video; Sperm Motility; Spermatozoa; Stimulation, Chemical | 1996 |
Effect of renin on brain arterioles and cerebral blood flow in rabbits.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Captopril; Cerebrovascular Circulation; Femoral Artery; Injections, Intravenous; Jugular Veins; Laser-Doppler Flowmetry; Male; Rabbits; Renin; Vasodilation | 1996 |
Analysis of responses to angiotensin I-(3-10) in the hindlimb vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Captopril; Cats; Dose-Response Relationship, Drug; Hindlimb; Receptors, Angiotensin; Regional Blood Flow; Vasoconstriction | 1996 |
Conformational analysis of neuropeptide Y-[18-36] analogs in hydrophobic environments.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Chromatography, High Pressure Liquid; Circular Dichroism; Models, Structural; Molecular Sequence Data; Neuropeptide Y; Peptide Fragments; Peptides; Protein Conformation; Protein Structure, Secondary; Structure-Activity Relationship; Thermodynamics | 1997 |
Forebrain angiotensin type 1 receptors and parabrachial serotonin in the control of NaCl and water intake.
Topics: Angiotensin I; Angiotensin II; Animals; Drinking; Injections; Male; Methysergide; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Rhombencephalon; Serotonin; Serotonin Antagonists; Sodium Chloride; Subfornical Organ; Water | 1996 |
Angiotensin II is generated from angiotensin I by bone cells and stimulates osteoclastic bone resorption in vitro.
Topics: Angiotensin I; Angiotensin II; Animals; Bone Resorption; Cattle; Cells, Cultured; Coculture Techniques; Dose-Response Relationship, Drug; Mice; Mice, Inbred CBA; Osteoblasts; Osteoclasts; Rats; Rats, Wistar; Stimulation, Chemical | 1997 |
Vascular angiotensin-converting enzyme expression regulates local angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Gene Expression; Hindlimb; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
Bovine aortic endothelial cells contain an angiotensin-(1-7) receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Cattle; Endothelium, Vascular; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 1997 |
Angiotensin-(1-7) augments bradykinin-induced vasodilation by competing with ACE and releasing nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Indomethacin; Male; Peptide Fragments; Vasodilation | 1997 |
Hypothalamic substance P release. Attenuated angiotensin responses in mRen2(27) transgenic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Hypothalamus; Male; Peptide Fragments; Rats; Substance P; Vasoconstrictor Agents | 1997 |
Distribution of Fos-immunoreactivity in rat brain following a dipsogenic dose of captopril and effects of angiotensin receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain Chemistry; Captopril; Drinking; Enalapril; Hypothalamus; Immunohistochemistry; Male; Naphthyridines; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley | 1997 |
Effect of angiotensin receptor blockade in the rabbit aorta: influence of the endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Enalapril; Endothelium, Vascular; Imidazoles; Losartan; Male; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles | 1996 |
Early versus delayed angiotensin-converting enzyme inhibition in experimental chronic heart failure. Effects on survival, hemodynamics, and cardiovascular remodeling.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diastole; Femoral Artery; Heart; Heart Failure; Hemodynamics; In Vitro Techniques; Lisinopril; Male; Muscle, Smooth, Vascular; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Survival Rate; Vascular Resistance; Ventricular Function, Left | 1997 |
Plasma angiotensins and human forearm circulation: effects of sympatho-adrenal activation.
Topics: Adrenal Glands; Adrenergic beta-Agonists; Adult; Angiotensin I; Angiotensin II; Epinephrine; Forearm; Humans; Male; Norepinephrine; Regional Blood Flow; Stress, Psychological; Sympathetic Nervous System; Vasodilation | 1997 |
The renin-angiotensin system in patients with repeated anaphylactic reactions during hymenoptera venom hyposensitization and sting challenge.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Arthropod Venoms; Child; Desensitization, Immunologic; Female; Humans; Hymenoptera; Immunotherapy; Insect Bites and Stings; Male; Middle Aged; Radioallergosorbent Test; Renin; Renin-Angiotensin System | 1997 |
Mapping of angiotensin II receptor subtypes in peripheral tissues of spontaneously hypertensive rats by in vitro autoradiography.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Heart; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1995 |
Angiotensin II activates distinct signal transduction pathways in astrocytes isolated from neonatal rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Bradykinin; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Epoprostenol; Humans; Hypothalamus; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol Diacylglycerol-Lyase; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Type C Phospholipases | 1997 |
Cardiovascular effects produced by microinjection of angiotensins and angiotensin antagonists into the ventrolateral medulla of freely moving rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles; Time Factors | 1997 |
Recognition of tissue- and subtype-specific modulation of angiotensin II receptors using antibodies against AT1 and AT2 receptors.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Antibodies; Antibody Formation; Antibody Specificity; Binding, Competitive; Cell Line; Humans; Immunoblotting; Male; Mice; Muscle, Smooth, Vascular; Myocardium; Organ Specificity; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1997 |
Video-microscopic assessment of the role of tissue angiotensin-converting enzyme in the control of the renal microcirculation.
Topics: Angiotensin I; Angiotensin II; Animals; Arterioles; Biphenyl Compounds; Imidazoles; Indoles; Kidney; Losartan; Male; Microscopy, Video; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction | 1997 |
Meet the "other" angiotensins.
Topics: Angiotensin I; Angiotensin II; Chymosin; Endopeptidases; Peptidyl-Dipeptidase A; Receptors, Angiotensin | 1997 |
Characterization of renin activity in brown adipose tissue.
Topics: Adipocytes; Adipose Tissue; Adipose Tissue, Brown; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Gene Expression; Hydrogen-Ion Concentration; Immunologic Techniques; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
Acute and chronic in vivo inhibition of angiotensin-converting enzyme by perindopril in the endothelium and adventitia of large arteries and organs of the rabbit.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arteries; Autoradiography; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Femoral Artery; Indoles; Kidney; Lung; Male; Myocardium; Peptidyl-Dipeptidase A; Perindopril; Rabbits; Renin | 1997 |
Vascular angiotensin-converting enzyme activity in cholesterol-fed rabbits: effects of enalapril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Arteriosclerosis; Blood Pressure; Cholesterol, Dietary; Enalapril; Male; Peptidyl-Dipeptidase A; Rabbits | 1997 |
Separation of proteins and peptides by capillary electrochromatography in diol- and octadecyl-modified etched capillaries.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Chromatography, High Pressure Liquid; Cytochrome c Group; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Muramidase; Myoglobin; Peptides; Proteins; Ribonuclease, Pancreatic; Silanes; Surface Properties | 1997 |
Angiotensin II stimulates rapid serine phosphorylation of transcription factor Stat3.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; CHO Cells; Cricetinae; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Flavonoids; Kinetics; Mitogen-Activated Protein Kinase Kinases; Myocardium; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase Inhibitors; Rats; Receptors, Angiotensin; Recombinant Proteins; Serine; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Transfection | 1997 |
Pressor and hormonal responses to angiotensin I infusion in healthy subjects of different angiotensin-converting enzyme genotypes.
Topics: Adult; Aldosterone; Alleles; Angiotensin I; Angiotensin II; Blood Pressure; DNA; Genotype; Heart Rate; Humans; Infusions, Intravenous; Male; Oligopeptides; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin; Renin-Angiotensin System; Sodium; Spectrophotometry, Ultraviolet; White People | 1997 |
Expression of a recombinant preproendothelin-1 gene in arteries stimulates vascular contractility.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Cells, Cultured; Endothelin-1; Endothelins; Gene Expression; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Protein Precursors; Protein Processing, Post-Translational; Rats; Swine; Transfection; Vasoconstriction | 1997 |
Possible participation of nitric oxide in the increase of norepinephrine release caused by angiotensin peptides in rat atria.
Topics: Angiotensin I; Angiotensin II; Animals; Drug Interactions; Electrophysiology; Enzyme Inhibitors; Female; Heart Atria; Heart Rate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar; Sympathomimetics | 1997 |
Cultured myofibroblasts generate angiotensin peptides de novo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aspartic Acid Endopeptidases; beta 2-Microglobulin; Blotting, Western; Cathepsin D; Cells, Cultured; Fluorescent Antibody Technique, Indirect; Gene Expression; Heart Ventricles; Lisinopril; Male; Myocardium; Peptide Biosynthesis; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1997 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 1st communication: antihypertensive effects of valsartan in hypertensive models.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Dogs; Enalapril; Heart Rate; Hypertension; Hypertension, Renal; Male; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Tetrazoles; Valine; Valsartan | 1997 |
Pharmacological profile of valsartan, a non-peptide angiotensin II type 1 receptor antagonist. 3rd communication: hemodynamic effects of valsartan in rats and dogs.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Circulation; Blood Pressure; Bradykinin; Cardiac Output; Dogs; Enalapril; Female; Heart Rate; Hemodynamics; Male; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Tetrazoles; Valine; Valsartan; Vascular Resistance | 1997 |
Differential inhibition of plasma versus tissue ACE by utibapril: biochemical and functional evidence for inhibition of vascular ACE activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Coronary Circulation; Heart; Hemodynamics; Male; Muscle Contraction; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Prodrugs; Rats; Rats, Wistar; Thiadiazoles; Vasoconstrictor Agents | 1997 |
Compartmentalization of angiotensin II generation in the dog heart. Evidence for independent mechanisms in intravascular and interstitial spaces.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Chromatography, High Pressure Liquid; Coronary Vessels; Dogs; Extracellular Space; Heart Rate; Myocardium; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Renin-Angiotensin System | 1997 |
Angiotensin I modulates Ca-transport systems in the rat heart through angiotensin II.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blotting, Northern; Calcium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Enalapril; Heart; In Situ Hybridization; Isradipine; Male; Myocardium; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium-Potassium-Exchanging ATPase | 1997 |
Effects of chronic hormone replacement on the renin-angiotensin system in cynomolgus monkeys.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Drug Interactions; Estradiol; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Macaca fascicularis; Medroxyprogesterone Acetate; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 1997 |
Atypical angiotensin II receptors coupled to phosphoinositide turnover/calcium signalling in catfish hepatocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Calcium; Cell Membrane; Egtazic Acid; Humans; Ictaluridae; Imidazoles; Liver; Losartan; Phosphatidylinositols; Pyridines; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1997 |
Renin angiotensin system in rabbit corpus cavernosum: functional characterization of angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Autoradiography; Male; Muscle, Smooth; Penis; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System | 1997 |
Long-term follow-up of a girl with the neonatal form of Bartter's syndrome.
Topics: Angiotensin I; Angiotensin II; Bartter Syndrome; Female; Follow-Up Studies; Growth; Humans; Indomethacin; Infant; Potassium; Spironolactone | 1997 |
Angiotensin II type 1 (AT1) receptor-mediated accumulation of angiotensin II in tissues and its intracellular half-life in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Chromatography, High Pressure Liquid; Diuretics; Endocytosis; Female; Furosemide; Half-Life; Iodine Radioisotopes; Kidney; Myocardium; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine | 1997 |
Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Blotting, Northern; Bradykinin; Cardiovascular System; DNA, Complementary; Electrophoresis, Agar Gel; Female; Gene Targeting; Heart Rate; Injections, Intravenous; Male; Mice; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Phenotype; Receptors, Angiotensin; RNA; RNA, Messenger | 1997 |
Characterization of the AT1 angiotensin II receptor expressed in guinea pig liver.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding, Competitive; Biphenyl Compounds; Enzyme Activation; Guinea Pigs; Imidazoles; Irbesartan; Liver; Losartan; Male; Polymerase Chain Reaction; Pyridines; Receptors, Angiotensin; RNA, Messenger; Tetrazoles | 1997 |
Characterization of angiotensin II formation in human isolated bladder by selective inhibitors of ACE and human chymase: a functional and biochemical study.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cell Membrane; Chymases; Humans; In Vitro Techniques; Middle Aged; Muscle Contraction; Oligopeptides; Serine Endopeptidases; Serine Proteinase Inhibitors; Urinary Bladder | 1997 |
Angiotensins stimulate catecholamine release from the chromaffin tissue of the rainbow trout.
Topics: Angiotensin I; Angiotensin II; Animals; Chromaffin System; Epinephrine; Female; Interrenal Gland; Male; Norepinephrine; Oncorhynchus mykiss; Receptors, Angiotensin | 1997 |
Renal vasoconstrictor response to 5-hydroxytryptamine in the in situ autoperfused rat kidney: involvement of angiotensin II and the 5-HT2 receptor activation.
Topics: Angiotensin I; Angiotensin II; Animals; Electric Stimulation; Kidney; Male; Perfusion; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction; Vasoconstrictor Agents | 1997 |
Angiotensin receptor subtypes in the uterine artery during ovine pregnancy.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Binding, Competitive; Female; Kinetics; Pregnancy; Pregnancy, Animal; Receptors, Angiotensin; Sheep; Uterus | 1997 |
Role of angiotensin in the dipsogenic effect of bradykinin in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Bradykinin; Brain; Captopril; Cerebral Ventricles; Drinking; Imidazoles; Immunohistochemistry; Losartan; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Thirst | 1997 |
[Angiotensin II antagonist for heart insufficiency].
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Biphenyl Compounds; Heart Failure; Humans; Imidazoles; Losartan; Prognosis; Tetrazoles | 1997 |
Angiotensin-(1-7) induces bradykinin-mediated hypotensive responses in anesthetized rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Hypotension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 1997 |
Renal effects of an angiotensin II antagonist in stroke-prone spontaneously hypertensive rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Imidazoles; Kidney; Kidney Function Tests; Kidney Glomerulus; Losartan; Organ Size; Proteinuria; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Tetrazoles; Tissue Embedding | 1997 |
Conversion of angiotensin I to angiotensin II by chymase activity in human pulmonary membranes.
Topics: Aged; Angiotensin I; Angiotensin II; Aprotinin; Chromatography, High Pressure Liquid; Chymases; Female; Humans; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Lung; Male; Membranes; Middle Aged; Peptidyl-Dipeptidase A; Protease Inhibitors; Serine Endopeptidases | 1997 |
In vitro pharmacological properties of KRH-594, a novel angiotensin II type 1 receptor antagonist.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Guinea Pigs; Ileum; In Vitro Techniques; Losartan; Male; Muscle Contraction; Rabbits; Tetrazoles; Thiadiazoles; Vasoconstrictor Agents | 1997 |
Angiotensin receptor antagonism and angiotensin converting enzyme inhibition improve diastolic dysfunction and Ca(2+)-ATPase expression in the sarcoplasmic reticulum in hypertensive cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Blotting, Northern; Blotting, Western; Calcium-Transporting ATPases; Captopril; Cardiomyopathy, Hypertrophic; Diastole; Dihydropyridines; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Mice; Mice, Transgenic; Myocardium; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sarcoplasmic Reticulum; Tetrazoles | 1997 |
Potentiation of the hypotensive effect of bradykinin by short-term infusion of angiotensin-(1-7) in normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Drug Synergism; Hypertension; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar | 1997 |
Role of angiotensin-(1-7) in the modulation of the baroreflex in renovascular hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Enalapril; Heart Rate; Hypertension, Renovascular; Injections, Intraventricular; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Wistar; Reflex | 1997 |
Contractile responses of cultured bovine retinal pericytes to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Nitroprusside; Retinal Vessels; Saralasin; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; GTP-Binding Proteins; Humans; Models, Structural; Molecular Sequence Data; Receptors, Angiotensin | 1994 |
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents | 1997 |
Angiotensin-(1-7) and the rat aorta: modulation by the endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1997 |
Effect of intratubular application of angiotensin 1-7 on nephron function.
Topics: Absorption; Angiotensin I; Angiotensin II; Animals; Feedback; Infusions, Parenteral; Kidney Function Tests; Kidney Tubules; Loop of Henle; Male; Nephrons; Peptide Fragments; Rats; Rats, Wistar | 1997 |
[Renal tissue angiotensins during converting enzyme inhibition of angiotensin I in spontaneously hypertensive rat].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Renal; In Vitro Techniques; Kidney; Male; Ramipril; Rats; Rats, Inbred SHR; Renin; Time Factors | 1997 |
AT1 receptor-mediated nuclear translocation of Raf-1 in brain neurons.
Topics: Angiotensin I; Angiotensin II; Animals; Biological Transport; Brain; Cell Nucleus; Fluorescent Antibody Technique; Immunoblotting; Microscopy, Confocal; Neurons; Proto-Oncogene Proteins c-raf; Rats; Rats, Inbred WKY; Receptors, Angiotensin | 1998 |
Effects of the dual metallopeptidase inhibitor, MDL 100,240, on regional haemodynamic responses to vasoactive peptides in conscious rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Benzazepines; Bradykinin; Endothelin-1; Hemodynamics; Male; Neprilysin; Protease Inhibitors; Pyridines; Rats | 1997 |
Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo.
Topics: Adrenal Glands; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cricetinae; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Mesocricetus; Middle Aged; Muscle, Smooth, Vascular; Rabbits; Rats; Tetrazoles; Thermodynamics | 1997 |
Signal transduction mechanisms involved in angiotensin-(1-7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Male; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Peptide Fragments; Phospholipases A; Phospholipases A2; Prostaglandins; Rabbits; Rats; Rats, Sprague-Dawley; Signal Transduction | 1998 |
[Pro11,D-Ala12]angiotensin I has rapid onset vasoconstrictor activity in the cat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Captopril; Cats; Female; Hindlimb; Imidazoles; Male; Norepinephrine; Pyridines; Receptors, Angiotensin; Tetrazoles; Time Factors; Vasoconstrictor Agents | 1997 |
Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Aorta, Thoracic; Blood Pressure; Estradiol; Estrogen Replacement Therapy; Female; Hypertension; Kidney; Mice; Models, Cardiovascular; Muscle, Smooth, Vascular; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; Renin-Angiotensin System; Vasoconstriction; Vasodilation | 1997 |
Different modulation of steroidogenesis and prostaglandin production in frog ovary in vitro by ACE and ANG II.
Topics: Androgens; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dinoprost; Dinoprostone; Estradiol; Female; Gonadal Steroid Hormones; Kidney; Lisinopril; Lung; Ovary; Peptidyl-Dipeptidase A; Progesterone; Prostaglandins; Rabbits; Rana catesbeiana; Rana esculenta | 1997 |
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 1998 |
Metabolism of angiotensin-(1-7) by angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cell Membrane; Dogs; Humans; Kinetics; Lisinopril; Lung; Models, Chemical; Peptide Fragments; Peptidyl-Dipeptidase A | 1998 |
Angiotensinases restrict locally generated angiotensin II to the blood vessel wall.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Vessels; Endopeptidases; Hindlimb; Kinetics; Male; Phenanthrolines; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renin | 1998 |
Angiotensin inhibits neurotransmission of calcitonin gene-related peptide-containing vasodilator nerves in mesenteric artery of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Mesenteric Arteries; Methoxamine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Saralasin; Synaptic Transmission; Thiazepines; Vasodilation; Vasomotor System | 1998 |
Vasodepressor actions of angiotensin-(1-7) unmasked during combined treatment with lisinopril and losartan.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Blood Pressure; Heart Rate; Imidazoles; Immunoglobulin G; Lisinopril; Losartan; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Vasodilation | 1998 |
Plasma active renin, angiotensin I, and angiotensin II during pregnancy and in preeclampsia.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Humans; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System | 1998 |
Comparison of blood pressure responses to intra-arterial and intra-venous injections of angiotensin I, angiotensin II and bradykinin.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Female; Injections, Intra-Arterial; Injections, Intravenous; Rats; Rats, Sprague-Dawley | 1998 |
Cardiac effects of angiotensin I and angiotensin II: dose-response studies in the isolated perfused rat heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Heart; Heart Rate; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Perfusion; Rats; Rats, Sprague-Dawley | 1998 |
Synergistic exacerbation of diastolic stiffness from short-term tachycardia-induced cardiodepression and angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Diastole; Dogs; Enzyme Activation; Female; Heart Failure; Heart Rate; Hemodynamics; Male; Metalloendopeptidases; Myocardial Contraction; Tachycardia; Time Factors | 1998 |
Actions of des-Asp angiotensin I on the aortic rings of the normo- and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Aorta; Drug Evaluation, Preclinical; Hypertension; In Vitro Techniques; Logistic Models; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasoconstriction | 1998 |
Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects.
Topics: Adult; Age Factors; Angiotensin I; Angiotensin II; Cross-Sectional Studies; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Peptide Fragments | 1998 |
N-domain-specific substrate and C-domain inhibitors of angiotensin-converting enzyme: angiotensin-(1-7) and keto-ACE.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arachidonic Acid; Bradykinin; Chlorides; CHO Cells; Cricetinae; Enzyme Repression; Humans; Hydrolysis; Peptide Fragments; Peptidyl-Dipeptidase A; Substrate Specificity; Transfection | 1998 |
Angiotensin II stimulation of the stress-activated protein kinases in renal mesangial cells is mediated by the angiotensin AT1 receptor subtype.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Glomerular Mesangium; Indoles; Phosphorylation; Protein Kinase C; Rats; Receptors, Angiotensin | 1998 |
Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition.
Topics: alpha 1-Antichymotrypsin; Angiotensin I; Angiotensin II; Catalysis; Cathepsin G; Cathepsins; Cell Membrane; Enzyme Activation; Humans; Kinetics; Leukocyte Elastase; Myeloblastin; Neutrophil Activation; Neutrophils; Peptidyl-Dipeptidase A; Proteinase Inhibitory Proteins, Secretory; Proteins; Serine Endopeptidases; Serine Proteinase Inhibitors | 1998 |
Reduction of cold-induced hypertension by antisense oligodeoxynucleotides to angiotensinogen mRNA and AT1-receptor mRNA in brain and blood.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antisense Elements (Genetics); Aorta; Autoradiography; Blood; Blood Pressure; Brain; Cold Temperature; Drinking; Hypertension; Kidney; Male; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 1998 |
The receptor subtype mediating the action of angiotensin II on intracellular sodium in rat proximal tubules.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Extracellular Space; Imidazoles; In Vitro Techniques; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium | 1998 |
Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin | 1998 |
Modulation of angiotensin-converting enzyme by nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Carotid Arteries; Diethylamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Male; Molsidomine; Muscle, Smooth, Vascular; Nitric Oxide; Oligopeptides; Oxadiazoles; Peptidyl-Dipeptidase A; Quinoxalines; Rabbits; Rats; Rats, Sprague-Dawley | 1998 |
Angiotensin 1-7 induces bradykinin-mediated relaxation in porcine coronary artery.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Vessels; Imidazoles; In Vitro Techniques; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Receptor, Bradykinin B2; Receptors, Bradykinin; Substance P; Swine; Vasodilation | 1998 |
Effects of the AT1 antagonist HR 720 in comparison to losartan on stimulated sympathetic outflow, blood pressure, and heart rate in pithed spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Catecholamines; Decerebrate State; Dose-Response Relationship, Drug; Electric Stimulation; Heart Rate; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Sympathetic Nervous System | 1998 |
Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Female; Iodine Radioisotopes; Myocardium; Renin; Swine | 1998 |
Angiotensin-(1-7) immunoreactivity in the hypothalamus of the (mRen-2d)27 transgenic rat.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Female; Hypothalamus; Image Processing, Computer-Assisted; Immunohistochemistry; Male; Mice; Oxytocin; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tissue Distribution; Vasopressins | 1998 |
Renal AT1 receptor: autoradiographic localization and quantification in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Dose-Response Relationship, Drug; Hypertension; Imidazoles; Kidney; Kidney Cortex; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1998 |
[7-D-ALA]-angiotensin 1-7 blocks renal actions of angiotensin 1-7 in the anesthetized rat.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Kidney; Kidney Function Tests; Kidney Tubules, Proximal; Losartan; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renal Circulation | 1998 |
Dissociation between the renal effects of angiotensin I and II in sodium-restricted normal subjects.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Catecholamines; Diet, Sodium-Restricted; Dose-Response Relationship, Drug; Double-Blind Method; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney; Male; Middle Aged; Regression Analysis; Renin; Time Factors; Vasoconstrictor Agents | 1998 |
Cold exposure regulates the renin-angiotensin system.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Body Weight; Cold Temperature; Drinking; Eating; Iodine Radioisotopes; Leptin; Liver; Male; Norepinephrine; Proteins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Time Factors | 1998 |
Pouch tissue and angiotensin peptide generation.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Aspartic Acid Endopeptidases; Cathepsin D; Collagen; Gene Expression; Imidazoles; Lisinopril; Losartan; Myocardium; Peptide Biosynthesis; Peptides; Peptidyl-Dipeptidase A; Pyridines; Rats; Renin; Transforming Growth Factor beta | 1998 |
Diuresis and natriuresis produced by long term administration of a selective Angiotensin-(1-7) antagonist in normotensive and hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Diuresis; Male; Natriuresis; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Time Factors | 1998 |
Ontogeny and regulation of cardiac angiotensin types 1 and 2 receptors during fetal life in sheep.
Topics: Angiotensin I; Angiotensin II; Animals; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Heart; Myocardium; Pregnancy; Receptors, Angiotensin; RNA, Messenger; Sheep | 1998 |
Endothelial vasoconstrictor prostanoids, vascular reactivity, and acute renal failure.
Topics: Acute Kidney Injury; Adrenergic Fibers; Angiotensin I; Angiotensin II; Animals; Aorta; Endothelium, Vascular; Kidney; Male; Norepinephrine; Rats; Rats, Inbred WKY; Renal Artery; Thromboxane A2; Vasoconstriction; Vasoconstrictor Agents | 1998 |
Converting enzyme determines plasma clearance of angiotensin-(1-7).
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Blood Pressure; Chromatography, High Pressure Liquid; Drug Combinations; Half-Life; Lisinopril; Losartan; Male; Metabolic Clearance Rate; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Species Specificity | 1998 |
Functional evidence for alternative ANG II-forming pathways in hamster cardiovascular system.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Aprotinin; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Captopril; Chymases; Cricetinae; Heart Ventricles; Humans; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Serine Endopeptidases; Substrate Specificity; Tetrazoles; Vasoconstriction | 1998 |
Specificity of Pseudomonas aeruginosa serralysin revisited, using biologically active peptides as substrates.
Topics: Angiotensin I; Angiotensin II; Arginine; Bacterial Proteins; Endopeptidases; Fibrin Fibrinogen Degradation Products; Hydrolysis; Kinetics; Mass Spectrometry; Metalloendopeptidases; Oligopeptides; Peptide Fragments; Pseudomonas aeruginosa; Substance P; Substrate Specificity | 1998 |
Effects of sustained flow reduction on postnatal intestinal circulation.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Hemodynamics; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Intestine, Small; Isometric Contraction; Mesenteric Arteries; Muscle Development; Muscle, Smooth; Muscle, Smooth, Vascular; omega-N-Methylarginine; Oxygen Consumption; Peptides; Perfusion; Regional Blood Flow; Swine; Vascular Resistance | 1998 |
Angiotensin II and insulin induce growth of ciliary artery smooth muscle: effects of AT1/AT2 antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Ciliary Arteries; DNA; DNA Replication; Dose-Response Relationship, Drug; Drug Combinations; Insulin; Muscle, Smooth, Vascular; Oligopeptides; Swine; Tetrazoles; Valine; Valsartan | 1998 |
Angiotensin II receptor antagonists for heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptors, Angiotensin | 1998 |
Purification and substrate specificity of an angiotensin converting elastase-2 from the rat mesenteric arterial bed perfusate.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Chromatography, Affinity; Chromatography, Gel; Kinetics; Male; Mesenteric Artery, Superior; Molecular Sequence Data; Pancreatic Elastase; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Substrate Specificity | 1998 |
Perindopril effects on angiotensin I elimination in lung after experimental myocardial injury induced by intracoronary microembolization in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Chromatography, High Pressure Liquid; Hemodynamics; Indoles; Infusions, Intravenous; Lung; Male; Microspheres; Perindopril; Rats; Rats, Wistar | 1998 |
Effect of angiotensin-(1-7) on ATPase activities in several tissues.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Kidney; Liver; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Sheep; Sodium-Potassium-Exchanging ATPase; Synaptosomes | 1998 |
[Tissue concentration and secretion of renin in human placental villi during early pregnancy].
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Chorionic Villi; Female; Gestational Age; Humans; Pregnancy; Pregnancy Trimester, First; Renin | 1997 |
Functional role of chymase in angiotensin II formation in human vascular tissue.
Topics: alpha 1-Antitrypsin; Angiotensin I; Angiotensin II; Blood Vessels; Chymases; Female; Humans; Male; Middle Aged; Serine Endopeptidases; Vasoconstriction | 1998 |
Do intraocular angiotensin II levels, plasma prothrombotic factors and endothelial dysfunction contribute to proliferative diabetic retinopathy?
Topics: Aged; Angiotensin I; Angiotensin II; Aqueous Humor; Blood Pressure; Cell Division; Cross-Sectional Studies; Diabetic Retinopathy; Endothelium, Vascular; Female; Hemorheology; Humans; Lipoprotein(a); Male; Neovascularization, Pathologic; P-Selectin; Retinal Neovascularization; Retinal Vessels; Thrombosis | 1998 |
The renin-angiotensin system in the vessel wall.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Aorta; Blood Vessels; Coronary Vessels; Hindlimb; Humans; Hypertension, Renovascular; In Vitro Techniques; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Swine | 1998 |
Direct vasoconstrictor action of homologous angiotensin II on isolated arterial ring preparations in an elasmobranch fish.
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Vessels; Brachial Artery; Captopril; Celiac Artery; Dogfish; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Mammals; Norepinephrine; Phentolamine; Receptors, Angiotensin; Saralasin; Vasoconstriction | 1998 |
Dual pathway for angiotensin II formation in human internal mammary arteries.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Female; Humans; Mammary Arteries; Middle Aged; Oligopeptides; Renin-Angiotensin System; Vasoconstriction | 1998 |
Interaction of bradykinin and angiotensin-(1-7) in the central modulation of the baroreflex control of the heart rate.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Animals; Baroreflex; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Rats; Rats, Wistar | 1998 |
Effect of selective angiotensin antagonists on the antidiuresis produced by angiotensin-(1-7) in water-loaded rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Diuresis; Drinking; Kidney; Losartan; Male; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Agents | 1998 |
The hyperglycemia induced by angiotensin II in rats is mediated by AT1 receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Hyperglycemia; Losartan; Male; Rats; Rats, Wistar; Receptors, Angiotensin; Vasoconstrictor Agents | 1998 |
Adrenal, kidney, and heart angiotensins in female murine Ren-2 transfected hypertensive rats.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensins; Animals; Animals, Genetically Modified; Chromatography, High Pressure Liquid; Estrus; Female; Hemodynamics; Hypertension; Kidney; Mice; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Transgenes | 1998 |
The hemoregulatory peptide N-acetyl-ser-asp-lys-pro impairs angiotensin I-induced contractions in rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Drug Interactions; In Vitro Techniques; Male; Oligopeptides; Rats; Rats, Wistar; Vasoconstriction | 1998 |
Angiotensin I-to-II conversion in the human renal vascular bed.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Animals; Female; Humans; Infusions, Intra-Arterial; Iodine Radioisotopes; Kidney; Male; Middle Aged; Renal Artery; Renal Circulation; Renal Veins; Swine | 1998 |
Changes in cardiac ANG II postmyocardial infarction in rats: effects of nephrectomy and ACE inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Heart Ventricles; Isoquinolines; Male; Myocardial Infarction; Myocardium; Nephrectomy; Quinapril; Rats; Rats, Wistar; Renin; Tetrahydroisoquinolines | 1999 |
Differential regulation of renal angiotensin subtype AT1A and AT2 receptor protein in rats with angiotensin-dependent hypertension.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Animals; Blotting, Western; Down-Regulation; Female; Gene Expression Regulation; Hypertension; Hypertension, Renal; Immunohistochemistry; Kidney; Kidney Glomerulus; Kidney Tubules; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1999 |
Proximal tubular angiotensin II levels and renal functional responses to AT1 receptor blockade in nonclipped kidneys of Goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Data Interpretation, Statistical; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Kidney Tubules, Proximal; Male; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Tetrazoles | 1999 |
Angiotensin-(1-7) reduces smooth muscle growth after vascular injury.
Topics: Angiotensin I; Angiotensin II; Animals; Carotid Artery Injuries; Carotid Artery, Common; Catheterization; Cell Division; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tunica Intima | 1999 |
Effects of human prorenin in rats transgenic for human angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Chemotherapy, Cancer, Regional Perfusion; Enzyme Precursors; Female; Humans; Infusions, Intravenous; Kinetics; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renin | 1999 |
Regulation of angiotensin II type 1 receptor mRNA and protein in angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Gene Expression Regulation; Hypertension; Infusions, Intravenous; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic | 1999 |
Roles of AT1 and AT2 receptors in the hypertensive Ren-2 gene transgenic rat kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Blood Pressure; Heart Rate; Hemodynamics; Homozygote; Hypertension; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values; Renal Circulation; Renin | 1999 |
Vascular injury causes neointimal formation in angiotensin II type 1a receptor knockout mice.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Carotid Artery Injuries; Mice; Mice, Knockout; Receptors, Angiotensin; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tunica Intima | 1999 |
Local renin-angiotensin system and mitogen-activated protein kinase activation in rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Captopril; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Male; Nephrectomy; Pepstatins; Protease Inhibitors; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Vasoconstrictor Agents | 1999 |
Effects of the new angiotensin II type 1 receptor antagonist KRH-594 on several types of experimental hypertension.
Topics: Administration, Oral; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Callithrix; Dogs; Female; Heart Rate; Hypertension; Kidney Function Tests; Male; Mice; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Species Specificity; Tetrazoles; Thiadiazoles | 1999 |
Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; COS Cells; Phenylalanine; Receptors, Angiotensin; Tyrosine | 1999 |
Comparison of irbesartan with captopril effects on cardiac hypertrophy and gene expression in heart failure-prone male SHHF/Mcc-fa(cp) rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Dose-Response Relationship, Drug; Echocardiography; Gene Expression; Heart Failure; Irbesartan; Isoenzymes; Male; Myosin Heavy Chains; Organ Size; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; RNA, Messenger; Systole; Tetrazoles | 1999 |
Analysis of responses to angiotensin I (3-10) and Leu3 angiotensin (3-8) in the pulmonary vascular bed of the cat.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Male; Peptide Fragments; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
Insertion/deletion angiotensin converting enzyme gene polymorphism affects the microvascular structure of the kidney in patients with nondiabetic renal disease.
Topics: Adult; Angiotensin I; Angiotensin II; Biopsy; Disease Progression; DNA; DNA Primers; Female; Follow-Up Studies; Gene Deletion; Genotype; Humans; Kidney Diseases; Kidney Medulla; Male; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Renal Artery; Renin | 1999 |
Contractile effects by intracellular angiotensin II via receptors with a distinct pharmacological profile in rat aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Peptides; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Vasoconstriction | 1999 |
Angiotensin-converting enzyme inhibition as antiatherosclerotic therapy: no answer yet.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Coronary Artery Disease; Disease Progression; Humans; Rats; Treatment Outcome | 1999 |
Vascular response to angiotensin II is exaggerated through an upregulation of AT1 receptor in AT2 knockout mice.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Aorta; Base Sequence; Binding, Competitive; DNA Primers; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Protein Binding; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction | 1999 |
Differential response of angiotensin peptides in the urine of hypertensive animals.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Body Weight; Drinking; Electrolytes; Hemodynamics; Hypertension; Lisinopril; Losartan; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley | 1999 |
Functional evidence for subfornical organ-intrinsic conversion of angiotensin I to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Drinking; Electrophysiology; Losartan; Male; Rats; Rats, Wistar; Reaction Time; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Subfornical Organ | 1999 |
Evidence for a causal role of the renin-angiotensin system in nitrate tolerance.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Female; Gene Expression; Losartan; Luminescent Measurements; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide; Nitroglycerin; Peptidyl-Dipeptidase A; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sulfonamides; Superoxides; Vasoconstriction; Vasodilation; Vasodilator Agents | 1999 |
Intrarenal angiotensin converting enzyme inhibition in spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dose-Response Relationship, Drug; Enalapril; Heart Rate; Hypertension; Infusion Pumps; Kidney; Kidney Medulla; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Species Specificity | 1999 |
Angiotensin-(1-7) can interact with the rat proximal tubule AT(4) receptor system.
Topics: Angiotensin I; Angiotensin II; Animals; Cattle; Cells, Cultured; Kidney Tubules, Proximal; Oxygen Consumption; Peptide Fragments; Rats; Receptors, Angiotensin; Sodium | 1999 |
Chymase-dependent angiotensin II formation in human vascular tissue.
Topics: Adult; alpha 1-Antitrypsin; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aprotinin; Arteries; Chymases; Female; Heparin; Humans; Lisinopril; Macromolecular Substances; Male; Mast Cells; Middle Aged; Oligopeptides; Protein Binding; Proteoglycans; Serine Endopeptidases; Serine Proteinase Inhibitors | 1999 |
Quantification of conversion and degradation of circulating angiotensin in rats.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Animals; CD13 Antigens; Female; Glutamyl Aminopeptidase; Heart Ventricles; Infusions, Intravenous; Injections, Intra-Arterial; Kidney; Lung; Male; Models, Biological; Pulmonary Circulation; Rats; Rats, Wistar; Renal Artery; Renal Circulation | 1999 |
Angiotensin-converting enzyme inhibition modifies angiotensin but not kinin peptide levels in human atrial tissue.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chromatography, High Pressure Liquid; Data Interpretation, Statistical; Female; Heart Atria; Humans; Kallidin; Kinins; Male; Middle Aged; Peptides; Peptidyl-Dipeptidase A; Radioimmunoassay | 1999 |
Angiotensin-(1-7) is a modulator of the human renin-angiotensin system.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Data Interpretation, Statistical; Female; Heart Atria; Humans; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Vasoconstriction | 1999 |
Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Bosentan; Calcium; Calcium Channel Blockers; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Space; Glycopeptides; Hypoxia; In Vitro Techniques; Indoles; Lisinopril; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Pulmonary Artery; Rats; Rats, Wistar; Sulfonamides | 1999 |
Haemorrhage increases the pressor effect of angiotensin-(1-7) but not of angiotensin II at the rat rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Hemorrhage; Male; Peptide Fragments; Pressoreceptors; Rats; Rats, Wistar; Sympathetic Nervous System | 1999 |
Angiotensin II is a growth factor in the peri-implantation rat embryo.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blastocyst; Culture Techniques; Embryonic and Fetal Development; Female; Growth Substances; Imidazoles; Nicotinic Acids; Pyridines; Rats; Rats, Wistar; Statistics, Nonparametric; Tetrazoles | 1999 |
Interactions between AT1 and AT2 receptors in uterine arteries from pregnant ewes.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Arteries; Female; Hypersensitivity; In Vitro Techniques; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Pregnancy; Pregnancy, Animal; Receptors, Angiotensin; Sheep; Uterus | 1999 |
Distribution of angiotensin AT1 and AT2 receptor subtypes in the rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Immunohistochemistry; Kidney; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; RNA, Messenger | 1999 |
Differing effects of enalapril and losartan on renal medullary blood flow and renal interstitial hydrostatic pressure in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Enalapril; Hydrostatic Pressure; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation | 1999 |
Alternative angiotensin II formation in rat arteries occurs only at very high concentrations of angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Arteries; Benzimidazoles; Biphenyl Compounds; Carotid Arteries; Cricetinae; Male; Mesocricetus; Pressoreceptors; Rats; Rats, Inbred WKY; Serine Proteinase Inhibitors; Tetrazoles; Time Factors; Vasoconstriction | 1999 |
Renal responses to AT1 blockade in angiotensin II-induced hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Glomerular Filtration Rate; Hypertension, Renal; Losartan; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium | 1997 |
Role of mast cell chymase in angiotensin-induced vascular contraction of hamster cheek pouch microvessels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chymases; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Male; Mast Cells; Microcirculation; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; p-Methoxy-N-methylphenethylamine; Serine Endopeptidases; Serine Proteinase Inhibitors | 1999 |
State-of-the-Art lecture. Antiproliferative actions of angiotensin-(1-7) in vascular smooth muscle.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiovascular Diseases; Cell Division; Humans; Muscle, Smooth, Vascular; Peptide Fragments | 1999 |
Cardiovascular effects of angiotensin-(1-7) in conscious spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Drug Interactions; Hypertension; Infusions, Intravenous; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors | 1999 |
Interactions of the systemic and brain renin-angiotensin systems in the control of drinking and the central mediation of pressor responses.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain Chemistry; Captopril; Central Nervous System; Drinking; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 1999 |
Angiotensin-(1-7) binds at the type 1 angiotensin II receptors in rat renal cortex.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Iodine Radioisotopes; Kidney Cortex; Losartan; Male; Peptide Fragments; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Angiotensin | 1999 |
Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Animals, Newborn; Captopril; Cells, Cultured; Culture Media, Serum-Free; Enzyme Precursors; Fibroblasts; Hypertrophy; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin; Stress, Mechanical | 1999 |
Renal vascular and biochemical responses to systemic renin inhibition in dogs at low renal perfusion pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Dogs; Heart Rate; Imidazoles; Kidney; Male; Perfusion; Renal Circulation; Renin; Renin-Angiotensin System | 1999 |
Increased bradykinin levels accompany the hemodynamic response to acute inhibition of angiotensin-converting enzyme in dogs with heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Cardiac Output; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Enalaprilat; Heart Failure; Indoles; Norepinephrine; Peptide Fragments; Ventricular Function, Left | 1999 |
Synergistic effect of angiotensin-(1-7) on bradykinin arteriolar dilation in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Enalaprilat; Mesenteric Arteries; Nitric Oxide; Peptide Fragments; Prostaglandins; Rats; Rats, Wistar; Receptor, Bradykinin B2; Vasodilation; Vasodilator Agents | 1999 |
Losartan reduces the vasorelaxant effect of atrial natriuretic peptide on basal tone in aorta.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Atrial Natriuretic Factor; Calcium; Female; Imidazoles; In Vitro Techniques; Intracellular Fluid; Isotonic Solutions; Losartan; Male; Muscle, Smooth, Vascular; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Resistance; Vasodilation | 1999 |
Pharmacological characterization of KR-30988, a novel non-peptide AT1 receptor antagonist, in rat, rabbit and dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Dogs; Furosemide; Hypertension, Renal; Imidazoles; Losartan; Male; Oligopeptides; Pressoreceptors; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Vasoconstriction | 1999 |
Plasma concentrations of angiotensin metabolites in young male normotensive and mild hypertensive subjects.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Humans; Hypertension; Male | 1999 |
Cardiovascular responses to angiotensins I and II in normotensive and hypertensive rats; effects of NO synthase inhibition or ET receptor antagonism.
Topics: Angiotensin I; Angiotensin II; Animals; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hemodynamics; Hypertension; Indans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Vasoconstrictor Agents | 1999 |
Functional role of local angiotensin-converting enzyme (ACE) in adrenal catecholamine secretion in vivo.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Captopril; Catecholamines; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine; Norepinephrine; Peptidyl-Dipeptidase A; Time Factors | 1999 |
The effects of angiotensin metabolites on the regulation of coagulation and fibrinolysis in cultured rat aortic endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta; Blood Coagulation; Endothelium, Vascular; Fibrinolysis; Gene Expression Regulation; Imidazoles; Lipoproteins; Losartan; Plasminogen Activator Inhibitor 1; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thromboplastin; Tissue Plasminogen Activator | 1999 |
Modulation of the intrahepatic renin-angiotensin system after stimulation of the gastric sodium monitor in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Gastric Mucosa; Liver; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Sodium; Time Factors | 2000 |
Regulation of angiotensin II production and angiotensin receptors in microvascular endothelial cells from bovine corpus luteum.
Topics: Angiotensin I; Angiotensin II; Animals; Cattle; Corpus Luteum; Endothelial Growth Factors; Endothelium, Vascular; Estradiol; Estrus; Female; Fibroblast Growth Factor 2; Gene Expression; Kinetics; Lymphokines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
[Involvement of chymase in angiogenesis in hamster sponge granulomas].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chymases; Chymotrypsin; Cricetinae; Endothelial Growth Factors; Granuloma; Hemoglobins; Humans; Lymphokines; Male; Mesocricetus; Neovascularization, Physiologic; Oligopeptides; Protein Isoforms; Serine Endopeptidases; Serine Proteinase Inhibitors; Tetrazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Changes in angiotensin converting enzyme activity in the renal vascular bed of streptozotocin-induced diabetic rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Drug Interactions; Kidney; Losartan; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renal Artery; Streptozocin; Vasoconstriction | 1999 |
Angiotensin III depressor action in the conscious rabbit is blocked by losartan but not PD 123319.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Imidazoles; Losartan; Male; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Opposing actions of angiotensins on angiogenesis.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Division; Male; Mice; Neovascularization, Physiologic; Peptide Fragments; Wound Healing | 2000 |
Secretory production of recombinant human chymase as an active form in Pichia pastoris.
Topics: Angiotensin I; Angiotensin II; Chymases; Culture Media; Gene Expression; Glycosylation; Humans; Kinetics; Pichia; Plasmids; Recombinant Proteins; Serine Endopeptidases | 2000 |
A novel stable inhibitor of endopeptidases EC 3.4.24.15 and 3.4.24.16 potentiates bradykinin-induced hypotension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Bradykinin; Dipeptides; Drug Evaluation; Drug Synergism; Heart Rate; Hypotension; Iodine Radioisotopes; Protease Inhibitors; Rabbits; Vasoconstrictor Agents | 2000 |
Chymase as a proangiogenic factor. A possible involvement of chymase-angiotensin-dependent pathway in the hamster sponge angiogenesis model.
Topics: Angiotensin I; Angiotensin II; Animals; Chymases; Cricetinae; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Granuloma; Hemoglobins; Humans; Immunohistochemistry; Male; Mesocricetus; Neovascularization, Physiologic; RNA, Messenger; Serine Endopeptidases; Time Factors; Transfection | 2000 |
The effects of Z13752A, a combined ACE/NEP inhibitor, on responses to coronary artery occlusion; a primary protective role for bradykinin.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Blood Pressure; Bradykinin; Coronary Circulation; Coronary Disease; Dogs; Dose-Response Relationship, Drug; Female; Kidney; Lung; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine | 2000 |
Vasoconstriction by in situ formed angiotensin II: role of ACE and chymase.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Child; Child, Preschool; Chymases; Coronary Vessels; Culture Techniques; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Imidazoles; Irbesartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Pyridines; Serine Endopeptidases; Swine; Tetrazoles; Vasoconstriction | 1999 |
Maximally recommended doses of angiotensin-converting enzyme (ACE) inhibitors do not completely prevent ACE-mediated formation of angiotensin II in chronic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enalapril; Female; Fosinopril; Heart Failure; Humans; Lisinopril; Male; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Treatment Failure; Valine; Valsartan | 2000 |
Gene polymorphism of the renin-angiotensin system associates with risk for lacunar infarction. The Ohasama study.
Topics: Aged; Alleles; Angiotensin I; Angiotensin II; Brain; Brain Infarction; DNA; Female; Genotype; Humans; Incidence; Japan; Magnetic Resonance Imaging; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Renin-Angiotensin System; Risk Factors; Rural Population | 2000 |
Angiotensin I to angiotensin II conversion in the human forearm and leg. Effect of the angiotensin converting enzyme gene insertion/deletion polymorphism.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; DNA Transposable Elements; Female; Forearm; Gene Deletion; Humans; Leg; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic | 1999 |
Cardiac interstitial fluid levels of angiotensin I and II in the pig.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Coronary Vessels; Extracellular Space; Female; Microdialysis; Myocardium; Swine | 1999 |
Effects of YM358, an angiotensin II type 1 (AT1) receptor antagonist, and enalapril on blood pressure and vasoconstriction in two renal hypertension models.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azoles; Biphenyl Compounds; Blood Pressure; Enalapril; Heart Rate; Hypertension, Renovascular; Male; Mesenteric Arteries; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Splanchnic Circulation; Vasoconstriction | 2000 |
Active immunization with angiotensin I peptide analogue vaccines selectively reduces the pressor effects of exogenous angiotensin I in conscious rats.
Topics: Algorithms; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies, Blocking; Blood Pressure; Blotting, Western; Carrier Proteins; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Male; Rats; Rats, Sprague-Dawley; Serine Proteinase Inhibitors; Vaccines; Vasoconstrictor Agents | 2000 |
Platelets and prostacyclin in arterial bypasses: implications for coronary artery surgery.
Topics: Angiotensin I; Angiotensin II; Blood Platelets; Carbazoles; Coronary Artery Bypass; Epoprostenol; Humans; In Vitro Techniques; Ketanserin; Mammary Arteries; Platelet Aggregation Inhibitors; Radial Artery; Receptors, Thromboxane; Serotonin Antagonists; Sulfonamides; Vasoconstriction | 2000 |
Effect of intrarenal infusion of angiotensin-(1-7) in the dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Diuresis; Dogs; Female; Glomerular Filtration Rate; Imidazoles; Infusions, Intra-Arterial; Kidney; Losartan; Male; Peptide Fragments; Receptors, Angiotensin; Renal Artery; Renal Circulation; Tetrazoles; Urodynamics; Vasodilator Agents | 2000 |
Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man.
Topics: Angiotensin I; Angiotensin II; Arteries; Drug Interactions; Forearm; Humans; Male; Norepinephrine; Peptide Fragments; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
The renin angiotensin system and hymenoptera venom anaphylaxis.
Topics: Adolescent; Adult; Aged; Aldosterone; Anaphylaxis; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensinogen; Bee Venoms; Child; Desensitization, Immunologic; Female; Homeostasis; Humans; Hypotension; Male; Middle Aged; Renin; Renin-Angiotensin System; Severity of Illness Index; Wasp Venoms | 1993 |
Structural comparison between type I and type II antagonists: possible implications in the drug design of AT1 antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Drug Design; Female; Magnetic Resonance Spectroscopy; Models, Molecular; Rats; Receptors, Angiotensin; Structure-Activity Relationship; Uterus | 2000 |
Various effects of angiotensin II on amygdaloid neuronal activity in normotensive control and hypertensive transgenic [TGR(mREN-2)27] rats.
Topics: Amygdala; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Evoked Potentials; Hypertension; Neurons; Rats; Rats, Sprague-Dawley | 2000 |
[Clinical efficacy of losartan: are there any differences between angiotensin II type I receptor antagonists and other drugs?].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Losartan; Receptors, Angiotensin | 2000 |
Effect of ACE inhibition on pressor, renal vascular, and adrenal responses to infusion of angiotensin I in normal subjects eating a low-salt diet.
Topics: Adolescent; Adrenal Glands; Adult; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricted; Enalapril; Humans; Infusions, Intravenous; Kidney; Male; Middle Aged; Reference Values; Renal Artery; Renal Plasma Flow; Renal Veins; Vasoconstriction | 2000 |
Renin angiotensin system of rabbit clitoral cavernosum: interaction with nitric oxide.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Clitoris; Culture Techniques; Female; Imidazoles; Losartan; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Pyridines; Rabbits; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2000 |
Angiotensin II analogues with sulphur-containing side-chains in position 5. A structure-activity relationship study.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin II; Animals; Cattle; Chromatography, Gel; In Vitro Techniques; Membranes; Rabbits; Receptors, Angiotensin; Structure-Activity Relationship | 2000 |
Renin angiotensin aldosterone system and drug allergies complicated with hypotension.
Topics: Adolescent; Adult; Aldosterone; Anaphylaxis; Angiotensin I; Angiotensin II; Cohort Studies; Drug Hypersensitivity; Female; Humans; Hypotension; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Statistics, Nonparametric | 2000 |
Plasma brain natriuretic peptides and renal hypertension.
Topics: Adolescent; Angiotensin I; Angiotensin II; Atrophy; Blood Pressure; Child; Child, Preschool; Female; Heart Failure; Humans; Hypertension, Renal; Kidney; Male; Natriuretic Peptide, Brain; Neuroblastoma; Renin; Ventricular Function, Left | 2000 |
Comparison of the antihypertensive effects of the new angiotensin II (AT1) receptor antagonist candesartan cilexetil (TCV-116) and the angiotensin converting enzyme inhibitor enalapril in rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Bradykinin; Enalapril; Enzyme Activation; Hypertension, Renal; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; Surgical Instruments; Tetrazoles; Vasoconstrictor Agents | 1996 |
A new method for simultaneous measurements of mast cell proteases in human vascular tissue.
Topics: Angiotensin I; Angiotensin II; Arteries; Carboxypeptidases; Carboxypeptidases A; Chromatography, High Pressure Liquid; Chymases; Endothelium, Vascular; Female; Humans; Male; Mast Cells; Middle Aged; Muscle, Smooth, Vascular; Peptide Fragments; Serine Endopeptidases; Tissue Extracts; Tryptases | 2000 |
Angiotensin-(1-7) increases osmotic water permeability in isolated toad skin.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Anura; Humans; Losartan; Oxytocin; Peptide Fragments; Permeability; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Skin; Skin Absorption; Vasoconstrictor Agents; Vasotocin; Water | 2000 |
Quantification of the contribution of type 1 and type 2 angiotensin II receptors to the net tissue specific effect of angiotensin II.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Blotting, Western; Ligands; Linear Models; Male; Models, Biological; Proteins; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sensitivity and Specificity; Sodium, Dietary | 2000 |
Contribution of angiotensin-(1-7) to blood pressure regulation in salt-depleted hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Blood Pressure Determination; Diet, Sodium-Restricted; Dipeptides; Dose-Response Relationship, Drug; Hypertension; Male; Peptide Fragments; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin | 2000 |
[Activation of the renin-angiotensin system and blood pressure variability in rats].
Topics: Adrenergic beta-Agonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Catecholamines; Catheters, Indwelling; Femoral Artery; Fourier Analysis; Heart Rate; Infusions, Intravenous; Isoproterenol; Male; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Renin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tachycardia; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2000 |
Cardiac hypertrophy and cardiac renin-angiotensin system in Dahl rats on high salt intake.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Brain Chemistry; Cardiomegaly; Gene Expression; Heart Ventricles; Immunoglobulin Fab Fragments; Male; Myocardium; Organ Size; Ouabain; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Dahl; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium, Dietary; Sympathetic Nervous System | 2000 |
Automation of data collection for matrix-assisted laser desorption/ionization mass spectrometry using a correlative analysis algorithm.
Topics: Algorithms; Angiotensin I; Angiotensin II; Electronic Data Processing; Enkephalin, Methionine; Insulin; Molecular Weight; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1998 |
Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles | 2000 |
Effects of ACE inhibitor, AT1 antagonist, and combined treatment in mice with heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiac Output; Chronic Disease; Echocardiography; Female; Heart; Heart Failure; Imidazoles; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Organ Size; Ramipril; Stroke Volume; Tetrazoles; Ventricular Remodeling | 2000 |
Pathways for angiotensin-(1---7) metabolism in pulmonary and renal tissues.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Membrane; Chromatography, High Pressure Liquid; Hydrolysis; In Vitro Techniques; Kidney; Lung; Male; Microvilli; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Rats | 2000 |
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine | 2000 |
Contribution of circulating renin to local synthesis of angiotensin peptides in the heart.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Gene Expression Regulation; Humans; Losartan; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Myocardium; Organ Specificity; Peptide Biosynthesis; Renin; Transgenes | 2000 |
Angiotensin-(1-7) does not affect norepinephrine neuronal uptake or catabolism in rat hypothalamus and atria.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Biological Transport; Catechol O-Methyltransferase; Female; Heart Atria; Hypothalamus; Monoamine Oxidase; Myocardium; Neurons; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar | 2000 |
SSeCKS gene expression in vascular smooth muscle cells: regulation by angiotensin II and a potential role in the regulation of PAI-1 gene expression.
Topics: A Kinase Anchor Proteins; Angiotensin I; Angiotensin II; Animals; Blotting, Northern; Blotting, Western; Cell Cycle Proteins; Cells, Cultured; COS Cells; Cytoplasm; Cytoskeleton; Dose-Response Relationship, Drug; Fibroblasts; Fluorescent Antibody Technique; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Luciferases; Mitogens; Muscle, Smooth, Vascular; Plasmids; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Rats; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Ribosomal, 18S; RNA, Ribosomal, 28S; Serine Proteinase Inhibitors; Signal Transduction; Time Factors; Transfection | 2000 |
Angiotensin II type 1 receptor blockade abolishes specific K(ATP)channel gene expression in rats with myocardial ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Blotting, Northern; Blotting, Western; DNA, Complementary; Lisinopril; Male; Myocardial Ischemia; Myocardium; Natriuretic Peptide, Brain; Potassium Channels; Potassium Channels, Inwardly Rectifying; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System; RNA; RNA, Messenger; Tetrazoles; Time Factors; Up-Regulation | 2000 |
Severe hyponatremia resulting from insufficient conversion of angiotensin I to angiotensin II.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Fludrocortisone; Humans; Hypoaldosteronism; Hyponatremia; Male; Middle Aged; Peptidyl-Dipeptidase A; Renin; Severity of Illness Index; Sodium | 2000 |
Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Hypertension; Male; Microinjections; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Receptors, Angiotensin; Solitary Nucleus | 2000 |
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glycopeptides; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Renin | 2001 |
Opposite regulation of brain angiotensin type 1 and type 2 receptors in cold-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Autoradiography; Brain; Cold Temperature; Hypertension; Male; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
The functional ratio of chymase and angiotensin converting enzyme in angiotensin I-induced vascular contraction in monkeys, dogs and rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Chymases; Dogs; Female; Lisinopril; Macaca; Male; Muscle Contraction; Oligopeptides; Peptidyl-Dipeptidase A; Potassium Chloride; Rats; Rats, Sprague-Dawley; Serine Endopeptidases; Serine Proteinase Inhibitors; Species Specificity; Vasoconstriction | 2000 |
High salt intake and the brain renin--angiotensin system in Dahl salt-sensitive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Brain; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hypertension; Immunoglobulin Fab Fragments; Injections, Intraventricular; Male; Ouabain; Peptidyl-Dipeptidase A; Radioimmunoassay; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium, Dietary; Spectrometry, Fluorescence | 2001 |
Angiotensin-(1--7) in the ovine fetus.
Topics: Allantois; Amniotic Fluid; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Female; Fetal Blood; Fetus; Gene Expression Regulation, Developmental; Gestational Age; Glomerular Filtration Rate; Kidney; Mice; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Sheep | 2001 |
Angiotensin II signaling to phospholipase D in renal microvascular smooth muscle cells in SHR.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brefeldin A; Cells, Cultured; Hypertension; Models, Chemical; Muscle, Smooth, Vascular; Phospholipase D; Protein Synthesis Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Artery; RNA, Messenger; Signal Transduction | 2001 |
Responses to central Na(+) and ouabain are attenuated in transgenic rats deficient in brain angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Blood Pressure; Brain; Cerebrospinal Fluid; Heart Rate; Injections, Intraventricular; Male; Ouabain; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium | 2001 |
Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arterioles; Bradykinin; Drug Synergism; Hypertension; Male; Mesenteric Arteries; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilation | 2001 |
Effects of angiotensin IV and angiotensin-(1-7) on basal and angiotensin II-stimulated cytosolic Ca2+ in mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Calcium; Cell Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glomerular Mesangium; Inositol Phosphates; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Vasoconstrictor Agents | 2001 |
Mechanisms of angiotensin-(1-7)-induced inhibition of angiogenesis.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Imidazoles; Losartan; Male; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Peptide Fragments; Prostheses and Implants; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2001 |
3-D QSAR studies of triazolinone based balanced AT1/AT2 receptor antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding Sites; Brain; Expert Systems; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rabbits; Triazoles | 2001 |
Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease.
Topics: Acetylcholine; Aged; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Bradykinin; Chymases; Enalaprilat; Female; Heart Failure; Humans; In Vitro Techniques; Losartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Serine Endopeptidases; Vascular Resistance; Vasoconstriction | 2001 |
Hormone replacement therapy increases plasma level of angiotensin II in postmenopausal hypertensive women.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Bradykinin; Female; Hormone Replacement Therapy; Humans; Hypertension; Middle Aged; Peptidyl-Dipeptidase A; Postmenopause; Renin | 2001 |
Endothelium-independent conversion of angiotensin I by vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Cell Compartmentation; Cells, Cultured; Coculture Techniques; Dexamethasone; Endothelium, Vascular; Enzyme Activation; Glucocorticoids; Humans; Iodine Radioisotopes; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Type C Phospholipases | 2001 |
Comparison of pulmonary vascular function and structure in early and established hypoxic pulmonary hypertension in rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin I; Angiotensin II; Animals; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Organ Size; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Renin-Angiotensin System; Serotonin; Vasodilator Agents | 2001 |
Evidence that the renin decrease during hypoxia is adenosine mediated in conscious dogs.
Topics: Acute Disease; Adenosine; Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carbon Dioxide; Consciousness; Diet, Sodium-Restricted; Dogs; Female; Heart Rate; Hemodynamics; Hypoxia; Oxygen; Partial Pressure; Potassium; Purinergic P1 Receptor Antagonists; Renin; Renin-Angiotensin System; Theophylline | 2001 |
Downregulation of the AT1A receptor by pharmacologic concentrations of Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Down-Regulation; Inositol Phosphates; Peptide Fragments; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2001 |
Angiotensin-(1-7) downregulates the angiotensin II type 1 receptor in vascular smooth muscle cells.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cells, Cultured; Down-Regulation; Imidazoles; Male; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regression Analysis; Tetrazoles; Type C Phospholipases | 2001 |
Automated high-throughput infusion ESI-MS with direct coupling to a microtiter plate.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Automation; Humans; Peptides; Spectrometry, Mass, Electrospray Ionization | 2001 |
The bladder angiotensin system in female rats: response to infusions of angiotensin I and the angiotensin converting enzyme inhibitor enalaprilat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Diestrus; Enalaprilat; Estrus; Female; Infusions, Intravenous; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Urinary Bladder | 2001 |
Cardiac angiotensin II formation in the clinical course of heart failure and its relationship with left ventricular function.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensinogen; Cardiomyopathy, Dilated; Cardiovascular Diseases; Chymases; Endothelin-1; Gene Expression; Gene Expression Regulation; Heart Ventricles; Immunohistochemistry; In Situ Hybridization; Insulin-Like Growth Factor I; Iodine Radioisotopes; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Platelet-Derived Growth Factor; Protein Precursors; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Serine Endopeptidases; Ventricular Function, Left | 2001 |
Selective inhibition of the renal angiotensin type 2 receptor increases blood pressure in conscious rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autacoids; Blood Pressure; Blotting, Western; Bradykinin; Cyclic GMP; Female; Kidney; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger | 2001 |
AT(1) antisense distinguishes receptors mediating angiotensin II actions in solitary tract nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Heart Rate; Male; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Solitary Nucleus | 2001 |
Angiotensin converting enzyme is the main contributor to angiotensin I-II conversion in the interstitium of the isolated perfused rat heart.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Extracellular Space; Male; Myocardium; Peptidyl-Dipeptidase A; Perfusion; Rats; Rats, Wistar; Tissue Distribution | 2001 |
The differential effect of angiotensin II and angiotensin 1-7 on norepinephrine, epinephrine, and dopamine concentrations in rat hypothalamus: the involvement of angiotensin receptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Catecholamines; Dopamine; Epinephrine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypothalamus; Male; Neurons; Norepinephrine; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin | 2001 |
Differential effects of angiotensin AT1 and AT2 receptors on the expression, translation and function of the Na+-H+ exchanger and Na+-HCO3- symporter in the rat heart after myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Animals; Bicarbonates; Blotting, Northern; Carrier Proteins; Male; Myocardial Infarction; Myocardium; Random Allocation; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers | 2001 |
Controlled hypertension, a transgenic toggle switch reveals differential mechanisms underlying vascular disease.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antioxidants; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Precursors; Hypertension; In Situ Hybridization; Indoles; Kidney; Kinetics; Mice; Pedigree; Peptidyl-Dipeptidase A; Precipitin Tests; Promoter Regions, Genetic; Rats; Rats, Inbred Strains; Renin; Time Factors; Transcription, Genetic; Transgenes | 2001 |
Cardiovascular regulation in TGR(mREN2)27 rats: 24h variation in plasma catecholamines, angiotensin peptides, and telemetric heart rate variability.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Animals, Genetically Modified; Catecholamines; Heart Rate; Heterozygote; Hypertension; Male; Peptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin; Time Factors | 2001 |
Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Bradycardia; Cell Communication; Connexin 43; Endothelium, Vascular; Exons; Gap Junctions; Gene Deletion; Gene Expression Regulation; Genes, Synthetic; Homeostasis; Hypotension; Integrases; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Nitric Oxide; Organ Specificity; Promoter Regions, Genetic; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Recombinant Fusion Proteins; Recombination, Genetic; Regulatory Sequences, Nucleic Acid; Transgenes; Vascular Resistance; Viral Proteins | 2001 |
Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Captopril; Chymases; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; In Vitro Techniques; Mammary Arteries; Oligopeptides; Peptidyl-Dipeptidase A; Recombinant Proteins; Serine Endopeptidases; Substrate Specificity; Vasoconstriction; Vasoconstrictor Agents | 2001 |
Circulating angiotensin II mediates sodium appetite in adrenalectomized rats.
Topics: Adrenalectomy; Angiotensin I; Angiotensin II; Animals; Appetite Regulation; Behavior, Animal; Blood Pressure; Captopril; Drinking; Drinking Behavior; Drug Administration Schedule; Infusions, Intravenous; Injections, Intraventricular; Male; Potassium; Rats; Rats, Long-Evans; Sodium; Sodium, Dietary | 2001 |
Renin uptake by the endothelium mediates vascular angiotensin formation.
Topics: Angiotensin I; Angiotensin II; Animals; Cholic Acids; Detergents; Endothelium, Vascular; Kidney; Male; Nephrectomy; Perfusion; Protein Transport; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; RNA, Messenger; Vasoconstrictor Agents | 2001 |
Persistent cardiovascular effects of chronic renin-angiotensin system inhibition following withdrawal in adult spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Vessels; Cardiomegaly; Cardiovascular System; Drug Administration Schedule; Heart Rate; Hydralazine; Hypertension; Kidney; Male; Motor Activity; Perindopril; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Vasodilator Agents | 2001 |
Effects of ACE inhibition and angiotensin II type 1 receptor blockade on cardiac function and G proteins in rats with chronic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chronic Disease; Collagen; Dose-Response Relationship, Drug; Fibroblasts; GTP-Binding Proteins; Heart; Heart Failure; Heart Septum; Heart Ventricles; Hemodynamics; Imidazoles; Indoles; Lung; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2001 |
Activation of the kallikrein-kinin system by cardiopulmonary bypass in humans.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Blood Proteins; Bradykinin; Cardiopulmonary Bypass; Carrier Proteins; Enzyme Activation; Heart Diseases; Humans; Kallidin; Kininogens; Kinins; Plasma Kallikrein; Serpins; Tissue Kallikreins; Veins | 2001 |
Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradykinin; Heart Ventricles; In Vitro Techniques; Indomethacin; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Rats; Rats, Wistar | 2001 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission | 2001 |
Effects of combined administration of ACE inhibitor and angiotensin II receptor antagonist are prevented by a high NaCl intake.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Blood; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Drug Synergism; Eating; Heart; Losartan; Organ Size; Perindopril; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 2001 |
Effects of P5, a novel oxazolo(3,2-a)pyridine derivative with a long-acting antihypertensive activity, on different agonist-mediated pressor responses in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Gluconate; Decerebrate State; Drug Interactions; Enzyme Inhibitors; Male; Nifedipine; Nitric Oxide Synthase; Potassium Channels; Pyridines; Rats; Rats, Wistar | 2001 |
The upregulation of angiotensin-converting enzyme during neointima formation does not have functional consequences.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Carotid Artery, Common; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Peptidyl-Dipeptidase A; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tunica Intima; Up-Regulation | 2001 |
Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system.
Topics: Adrenergic beta-Agonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Collagen; Coronary Circulation; Heart Rate; Isoproterenol; Isoquinolines; Losartan; Male; Myocardium; Organ Size; Peptidyl-Dipeptidase A; Quinapril; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrahydroisoquinolines | 2001 |
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cell Division; Chemokine CCL2; Femoral Artery; Inflammation; Interleukin-1; Interleukin-6; Leukocyte Common Antigens; Leukocytes; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima; Valine; Valsartan | 2001 |
Angiotensin-(1-7) reverts the stimulatory effect of angiotensin II on the proximal tubule Na(+)-ATPase activity via a A779-sensitive receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cell Membrane; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Tubules, Proximal; Losartan; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saralasin; Sodium-Potassium-Exchanging ATPase; Swine | 2002 |
The dipsogenic effect of the renin-angiotensin system in elasmobranch fish.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogfish; Drinking; Female; Fishes; Male; Papaverine; Renin-Angiotensin System; Thirst; Water-Electrolyte Balance | 2001 |
Release and degradation of angiotensin I and angiotensin II from angiotensinogen by neutrophil serine proteinases.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Binding Sites; Cathepsin G; Cathepsins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Humans; Inflammation; Models, Biological; Myeloblastin; Neutrophils; Pancreatic Elastase; Protein Binding; Serine Endopeptidases; Time Factors; Wound Healing | 2002 |
Isolation and properties of stachyrase A, a chymotrypsin-like serine proteinase from Stachybotrys chartarum.
Topics: alpha 1-Antichymotrypsin; alpha-Macroglobulins; Angiotensin I; Angiotensin II; Binding Sites; Bradykinin; Chymotrypsin; Collagen; Elastin; Neurotensin; Serine Endopeptidases; Serine Proteinase Inhibitors; Stachybotrys; Substance P; Tosylphenylalanyl Chloromethyl Ketone | 2002 |
Radioligand binding reveals chymase as the predominant enzyme for mediating tissue conversion of angiotensin I in the normal human heart.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Chymases; Enzyme Inhibitors; Female; Heart Ventricles; Humans; Male; Oligopeptides; Peptidyl-Dipeptidase A; Radioligand Assay; Serine Endopeptidases; Statistics, Nonparametric | 2002 |
Angiotensin peptides modulate bradykinin levels in the interstitium of the dog heart in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Bradykinin; Dogs; Heart; Hemodynamics; Imidazoles; Microdialysis; Myocardium; Peptide Fragments; Peptides; Pyridines | 2002 |
Vasoconstriction is determined by interstitial rather than circulating angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Carotid Arteries; Dose-Response Relationship, Drug; Femoral Artery; Imidazoles; In Vitro Techniques; Irbesartan; Isoquinolines; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrahydroisoquinolines; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Vasoactive intestinal peptide down-regulates the intrahepatic renin-angiotensin system in the anaesthetized rat.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Down-Regulation; Gastrointestinal Agents; Liver; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Vasoactive Intestinal Peptide | 2000 |
Evidence for activation of the renin-angiotensin system in the human prostate: increased angiotensin II and reduced AT(1) receptor expression in benign prostatic hyperplasia.
Topics: Angiotensin I; Angiotensin II; Case-Control Studies; Epithelium; Humans; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Prostate; Prostatic Hyperplasia; Receptors, Angiotensin; Renin-Angiotensin System | 2002 |
Ang II accumulation in rat renal endosomes during Ang II-induced hypertension: role of AT(1) receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dextrans; Endosomes; Flow Cytometry; Fluoresceins; Hypertension; Kidney; Male; Microvilli; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Systole; Tetrazoles | 2002 |
Renal interstitial fluid concentrations of angiotensins I and II in anesthetized rats.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blood Volume; Enalapril; Extracellular Space; Infusions, Intra-Arterial; Kidney; Microdialysis; Rats; Rats, Sprague-Dawley; Thiopental | 2002 |
Salt-sensitive hypertension resulting from nitric oxide synthase inhibition is associated with loss of regulation of angiotensin II in the rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Enzyme Inhibitors; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Effect of angiotensin-(1-7) on jejunal absorption of water in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Imidazoles; Indomethacin; Jejunum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Protein Binding; Pyridines; Rats; Rats, Wistar; Time Factors; Water | 2002 |
1A-779 attenuates angiotensin-(1-7) depressor response in salt-induced hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cyclic GMP; Dinoprostone; Epoprostenol; Hypertension; Male; Nitric Oxide; Peptide Fragments; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Salts; Thromboxane A2; Thromboxane B2; Time Factors | 2002 |
Activation of vascular tissue angiotensin-converting enzyme (ACE) in heart failure. Effects of ACE inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Vessels; Heart Failure; Humans | 2002 |
Urinary vasodilator and vasoconstrictor angiotensins during menstrual cycle, pregnancy, and lactation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Female; Humans; Lactation; Menstrual Cycle; Peptide Fragments; Pregnancy; Vasoconstriction; Vasodilation | 2001 |
Formation of angiotensin-(1-7) from angiotensin II by the venom of Conus geographus.
Topics: Angiotensin I; Angiotensin II; Animals; CHO Cells; Cricetinae; Humans; omega-Conotoxin GVIA; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tritium | 2002 |
Vasodilator action of angiotensin-(1-7) on isolated rabbit afferent arterioles.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Kidney Glomerulus; Male; Norepinephrine; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2002 |
Dysregulation of angiotensin II synthesis is associated with salt sensitivity in the spontaneous hypertensive rat.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Hypertension; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin; Sodium Chloride, Dietary | 2002 |
Val-Tyr as a natural antihypertensive dipeptide can be absorbed into the human circulatory blood system.
Topics: Absorption; Administration, Oral; Adult; Aldosterone; Angiotensin I; Angiotensin II; Antihypertensive Agents; Blood Circulation; Dipeptides; Dose-Response Relationship, Drug; Humans; Male | 2002 |
Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog.
Topics: Alabama; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Chymases; Disease Models, Animal; Dogs; Female; Heart Ventricles; Hemodynamics; Male; Mitral Valve Insufficiency; Receptor, Angiotensin, Type 1; Renin; Serine Endopeptidases; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling | 2002 |
Accelerated recovery from irradiation injury by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Bone Marrow Cells; Colony-Forming Units Assay; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Leukocyte Count; Lymphocyte Count; Megakaryocytes; Mice; Mice, Inbred C57BL; Peptide Fragments; Peptides; Platelet Count; Radiation Injuries, Experimental; Recombinant Proteins; Stem Cells | 2002 |
Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene.
Topics: Angiotensin I; Angiotensin II; Animals; Chymases; Gene Expression; Kidney; Kinetics; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutagenesis, Insertional; Myocardium; Peptidyl-Dipeptidase A; Serine Endopeptidases | 2002 |
Effects of angiotensins on day-night fluctuations and stress-induced changes in blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Autonomic Nervous System; Blood Pressure; Circadian Rhythm; Drug Administration Schedule; Heart Rate; Injections, Subcutaneous; Male; Peptide Fragments; Rats; Rats, Wistar; Restraint, Physical; Stress, Physiological; Telemetry | 2002 |
Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Brain; Cardiovascular System; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reference Values; Solitary Nucleus | 2002 |
Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Base Sequence; Blotting, Northern; Calcium; Cell Division; Cloning, Molecular; Cross-Linking Reagents; Cyclic AMP; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Precursors; Gene Library; Glomerular Mesangium; Humans; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Receptors, Cell Surface; Renin; RNA, Messenger; Time Factors; Tissue Distribution; Transcription, Genetic; Transfection; Vacuolar Proton-Translocating ATPases | 2002 |
Renal microvascular actions of angiotensin II fragments.
Topics: Angiotensin I; Angiotensin II; Animals; Hydronephrosis; In Vitro Techniques; Male; Microcirculation; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Vasoconstrictor Agents; Vasodilation | 2002 |
L-158,809 and (D-Ala(7))-angiotensin I/II (1-7) decrease PAI-1 release from human umbilical vein endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibrinolytic Agents; Humans; Imidazoles; Peptide Fragments; Plasminogen Activator Inhibitor 1; Tetrazoles; Tissue Plasminogen Activator; Umbilical Veins | 2002 |
Differential regulation of elevated renal angiotensin II in chronic renal ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Chronic Disease; Chymases; Cilazapril; Dogs; Hemodynamics; Hypertension, Renal; Imidazoles; Ischemia; Kidney; Male; Oligopeptides; Olmesartan Medoxomil; Peptidyl-Dipeptidase A; Renal Circulation; Renin-Angiotensin System; Serine Endopeptidases; Tetrazoles | 2002 |
The mechanism of the angiotensin-converting enzyme inhibitor quinapril is not related to bradykinin level in heart tissue.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Isoquinolines; Kidney; Male; Myocardium; Peptidyl-Dipeptidase A; Quinapril; Radioimmunoassay; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Tetrahydroisoquinolines; Time Factors; Tissue Distribution | 2002 |
[Peptide-protein complexes of angiotensins in the mechanisms of thirst].
Topics: Angiotensin I; Angiotensin II; Animals; Captopril; Cattle; Drinking Behavior; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Serum Albumin, Bovine; Thirst | 2002 |
Chymase inhibition suppresses high-cholesterol diet-induced lipid accumulation in the hamster aorta.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Aorta; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Chymases; Cricetinae; Male; Mesocricetus; Peptidyl-Dipeptidase A; Quinazolines; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Triglycerides; Tunica Intima | 2002 |
Separation and detection of angiotensin peptides by Cu(II) complexation and capillary electrophoresis with UV and electrochemical detection.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Biuret Reaction; Copper; Electrochemistry; Electrophoresis, Capillary; Humans; Spectrophotometry, Ultraviolet | 2002 |
Comparative effects of angiotensin IV and two hemorphins on angiotensin-converting enzyme activity.
Topics: Angiotensin I; Angiotensin II; Animals; Hemoglobins; Peptide Fragments; Peptidyl-Dipeptidase A; Rats | 2002 |
Renal interstitial fluid angiotensin I and angiotensin II concentrations during local angiotensin-converting enzyme inhibition.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalaprilat; Extracellular Space; Kidney Cortex; Microdialysis; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2002 |
Characterization of PgPepO, a bacterial homologue of endothelin-converting enzyme-1.
Topics: Angiotensin I; Angiotensin II; Aspartic Acid Endopeptidases; Bacterial Proteins; Bradykinin; Chromatography, High Pressure Liquid; Endothelin-Converting Enzymes; Enzyme Activation; Enzyme Inhibitors; Glycopeptides; Humans; Hydrolysis; Inhibitory Concentration 50; Metalloendopeptidases; Neurotensin; Porphyromonas gingivalis; Substance P; Thiorphan | 2002 |
Vasopeptidase inhibition and Ang-(1-7) in the spontaneously hypertensive rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Thiazepines | 2002 |
Angiotensin II vs its type I antagonists: conformational requirements for receptor binding assessed from NMR spectroscopic and receptor docking experiments.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Receptors, Angiotensin; Saralasin; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2002 |
Transendothelial transport of renin-angiotensin system components.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Biological Transport; Endothelium, Vascular; Enzyme Precursors; Horseradish Peroxidase; Humans; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Serine Proteinase Inhibitors; Serum Albumin; Umbilical Veins | 2002 |
Effects of dietary salt changes on renal renin-angiotensin system in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney Cortex; Kidney Medulla; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Diet, Sodium-Restricted; Kidney Cortex; Kidney Medulla; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary | 2002 |
Hypotensive effect of ANG II and ANG-(1-7) at the caudal ventrolateral medulla involves different mechanisms.
Topics: Adrenergic Antagonists; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Cholinergic Antagonists; Depression, Chemical; Heart Rate; Male; Medulla Oblongata; Microinjections; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 2002 |
The role of locally expressed angiotensin converting enzyme in cardiac remodeling after myocardial infarction in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Collagen; Hemodynamics; Kidney; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Ventricular Remodeling | 2002 |
Angiotensin-(1-7) inhibits angiotensin II-induced signal transduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Enzyme Activation; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction | 2002 |
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis | 2002 |
Intrarenal infusion of angiotensin-(1-7) modulates renal functional responses to exogenous angiotensin II in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Glomerular Filtration Rate; Imidazoles; In Vitro Techniques; Kidney; Kidney Function Tests; Male; Organ Size; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Renal Circulation; Sodium; Urodynamics | 2002 |
Angiotensin-(1-7) in normal and preeclamptic pregnancy.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Hormones; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Pregnancy Trimester, Third; Reference Values; Renin | 2002 |
Angiotensin receptors contribute to blood pressure homeostasis in salt-depleted SHR.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Homeostasis; Imidazoles; Immune Sera; Losartan; Male; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Time Factors | 2003 |
Paradoxical augmentation of bradykinin-induced vasodilatation by xanthine/xanthine oxidase-derived free radicals in isolated guinea pig heart.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Coronary Circulation; Female; Free Radicals; Guinea Pigs; In Vitro Techniques; Male; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Xanthine; Xanthine Oxidase | 2002 |
Isolation, synthesis, and biological activity of flounder [Asn1,Ile5,Thr9] angiotensin I.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Flounder; Humans; Injections, Intra-Arterial; Sequence Analysis; Vasotocin | 2003 |
[The levels of angiotensin and aldosterone in gases of hyperthyroid Graves' disease with and without hypokalemic periodic paralysis].
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Female; Graves Disease; Humans; Hypokalemic Periodic Paralysis; Male | 2001 |
[Study on the determination of peptide mixture by HPCE].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Electrophoresis, Capillary; Neurokinin A; Peptides; Somatostatin; Substance P | 2000 |
Subcellular identification of angiotensin I/II- and angiotensin II (AT1)-receptor-immunoreactivity in the central nervous system of rats.
Topics: Angiotensin I; Angiotensin II; Animals; Artifacts; Axons; Brain; Endoplasmic Reticulum; Endothelium; Immunohistochemistry; In Vitro Techniques; Nerve Endings; Neurons; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin | 2003 |
Leukocyte angiotensin II levels inpatients with essential hypertension:relation to insulin resistance.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Body Mass Index; Chromatography, High Pressure Liquid; Cilazapril; Female; Homeostasis; Humans; Hypertension; Insulin; Insulin Resistance; Leptin; Leukocytes; Male; Middle Aged | 2003 |
Pressor responsiveness to angiotensin in soy-fed spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Caseins; Dose-Response Relationship, Drug; Female; Glycine max; Hypertension; Male; Ovariectomy; Rats; Rats, Inbred SHR | 2002 |
Systemic and regional hemodynamic effects of angiotensin-(1-7) in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Hemodynamics; Male; Peptide Fragments; Rats; Rats, Wistar; Regional Blood Flow; Vascular Resistance; Vasodilator Agents | 2003 |
Mice lacking endothelial ACE: normal blood pressure with elevated angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Endothelium, Vascular; Female; Genotype; Heterozygote; Kidney; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Peptidyl-Dipeptidase A; Plasma Volume; Sodium; Sodium, Dietary | 2003 |
ACE-versus chymase-dependent angiotensin II generation in human coronary arteries: a matter of efficiency?
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chymases; Coronary Vessels; Extracellular Space; Female; Humans; In Vitro Techniques; Isotonic Solutions; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Perfusion; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Vasoconstriction | 2003 |
Role of angiotensin in body fluid homeostasis of mice: fluid intake, plasma hormones, and brain Fos.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Behavior, Animal; Body Fluids; Body Water; Brain Chemistry; Drinking; Enalapril; Female; Furosemide; Hematocrit; Homeostasis; Hormones; Male; Mice; Mice, Inbred Strains; Polyethylene Glycols; Proto-Oncogene Proteins c-fos; Renin; Sodium Chloride; Subfornical Organ; Water-Electrolyte Balance | 2003 |
Angiotensins in plasma of hypertensive rats and human.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Disease Models, Animal; Enalapril; Humans; Hypertension; Male; Middle Aged; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Rats, Wistar | 2003 |
Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cicatrix; Female; Mice; Mice, Inbred NOD; Peptide Fragments; Rats; Rats, Sprague-Dawley; Time Factors; Wound Healing | 2003 |
Characterization of a new selective antagonist for angiotensin-(1-7), D-pro7-angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Culture Techniques; Male; Peptide Fragments; Rats; Rats, Wistar; Renal Agents; Vasodilation | 2003 |
Mouse mast cell protease-1 cleaves angiotensin I to form angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Chromatography, High Pressure Liquid; Chymases; Humans; Mice; Serine Endopeptidases | 2003 |
Effect of angiotensin II and angiotensin(1-7) on hematopoietic recovery after intravenous chemotherapy.
Topics: Angiotensin I; Angiotensin II; Animals; Antineoplastic Agents; Blood Platelets; Cyclophosphamide; Female; Fluorouracil; Hematopoiesis; Hematopoietic Stem Cells; Leukocytes; Mice; Peptide Fragments | 2003 |
Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Cell Culture Techniques; Culture Media; Glomerular Mesangium; Glucose Solution, Hypertonic; Male; Rats; Rats, Sprague-Dawley; Renin | 2003 |
Depressor effect induced by dipeptide, Val-Tyr, in hypertensive transgenic mice is due, in part, to the suppression of human circulating renin-angiotensin system.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dipeptides; Humans; Hypertension; Male; Mice; Mice, Transgenic; Renin-Angiotensin System | 2003 |
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation | 2003 |
Angiotensin-(1-7): a novel peptide in the ovary.
Topics: Angiotensin I; Angiotensin II; Animals; Chorionic Gonadotropin; Estrus; Female; Horses; In Vitro Techniques; Osmolar Concentration; Ovary; Peptide Fragments; Proestrus; Rats; Rats, Wistar | 2003 |
Comparison of the solution structures of angiotensin I & II. Implication for structure-function relationship.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Dimethyl Sulfoxide; Free Radical Scavengers; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptide Biosynthesis; Protein Conformation; Protein Structure, Tertiary; Protons; Renin-Angiotensin System; Structure-Activity Relationship | 2003 |
Maintenance of normal blood pressure and renal functions are independent effects of angiotensin-converting enzyme.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Endothelium, Vascular; Female; Gene Expression Regulation, Enzymologic; Infertility, Male; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Peptidyl-Dipeptidase A; Pregnancy; Transgenes | 2003 |
Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin: insights from selective inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Bradykinin; Dose-Response Relationship, Drug; Drug Stability; Humans; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Peptidyl-Dipeptidase A; Phosphinic Acids; Substrate Specificity | 2003 |
Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Drug Interactions; Imidazoles; In Vitro Techniques; Losartan; Male; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2003 |
Human-derived vascular smooth muscle cells produce angiotensin II by changing to the synthetic phenotype.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Cathepsin D; Cathepsin G; Cathepsins; Cell Division; Cells, Cultured; Fibronectins; Humans; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligonucleotides, Antisense; Oligopeptides; Phenotype; Serine Endopeptidases; Serine Proteinase Inhibitors; Thiazepines | 2003 |
Effects of angiotensin-(1-7) and other bioactive components of the renin-angiotensin system on vascular resistance and noradrenaline release in rat kidney.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Kidney; Male; Norepinephrine; Peptide Fragments; Rats; Rats, Inbred WKY; Renin-Angiotensin System; Synaptic Transmission; Vascular Resistance; Vasoconstrictor Agents | 2003 |
Angioedema and AT1 receptor blockers: proceed with caution.
Topics: Angioedema; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Humans; Losartan | 2003 |
Angiotensin I conversion to angiotensin II stimulates cortical collecting duct sodium transport.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Captopril; Culture Techniques; Kidney Tubules, Collecting; Microscopy, Fluorescence; Peptidyl-Dipeptidase A; Rabbits; Sodium | 2003 |
Effects of different angiotensins during acute, double blockade of the renin system in conscious dogs.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Consciousness; Diuresis; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Natriuresis; Peptide Fragments; Renin; Renin-Angiotensin System; Vasoconstrictor Agents; Vasopressins | 2003 |
Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Female; Immunohistochemistry; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 2003 |
Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Body Weight; Cardiomegaly; Collagen; Hemodynamics; Losartan; Mice; Mice, Transgenic; Myocardium; Organ Size; Organ Specificity; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Tumor Necrosis Factor-alpha; Ventricular Remodeling | 2003 |
Do studies with ACE N- and C-domain-selective inhibitors provide evidence for a non-ACE, non-chymase angiotensin II-forming pathway?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Bradykinin; Chymases; Humans; Molecular Mimicry; Oligopeptides; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Serine Endopeptidases; Substrate Specificity | 2003 |
Hypotensive effect of butein via the inhibition of angiotensin converting enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Chalcone; Chalcones; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents | 2003 |
Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Peptide Fragments; Prostaglandins; Rats; Rats, Sprague-Dawley | 2003 |
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-I-converting enzyme deletion/deletion genotype.
Topics: Adult; Angiotensin I; Angiotensin II; Antihypertensive Agents; Female; Gene Deletion; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Vasoconstrictor Agents | 2003 |
Angiotensin-(1-7) formation in the intact human heart: in vivo dependence on angiotensin II as substrate.
Topics: Adult; Angiotensin I; Angiotensin II; Coronary Vessels; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardium; Peptide Fragments | 2003 |
Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Carboxypeptidases; Cardiac Output, Low; Female; Heart Ventricles; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Up-Regulation | 2003 |
Angiotensin II type 1 receptor-mediated augmentation of renal interstitial fluid angiotensin II in angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Body Weight; Extracellular Fluid; Hypertension, Renal; Kidney; Male; Microdialysis; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstrictor Agents | 2003 |
Angiotensin-(1-7) stimulates water transport in rat inner medullary collecting duct: evidence for involvement of vasopressin V2 receptors.
Topics: Angiotensin I; Angiotensin II; Animals; Antidiuretic Hormone Receptor Antagonists; Biological Transport; Colforsin; Cyclic AMP; Kidney Tubules, Collecting; Osmosis; Peptide Fragments; Permeability; Protein Isoforms; Rats; Receptors, Vasopressin; Signal Transduction; Water | 2003 |
Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Blood Pressure; Cerebral Ventricles; Cerebrospinal Fluid; Heart Rate; Hemorrhage; Hypertension; Hypotension; Hypothalamus; Injections, Intraventricular; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin; Shock, Hemorrhagic; Species Specificity | 2003 |
High dietary sodium blunts affects of angiotensin-converting enzyme inhibition on vascular angiotensin I-to-angiotensin II conversion in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; In Vitro Techniques; Rats; Rats, Wistar; Sodium, Dietary | 2003 |
[Dosage equivalents of AT1-receptor antagonists available in Germany].
Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan | 2003 |
The role of Ang (1-7) in mediating the chronic hypotensive effects of losartan in normal rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Chronic Disease; Drug Interactions; Heart Rate; Hypotension; Losartan; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2003 |
Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Binding Sites; Carboxypeptidases; Chlorides; CHO Cells; Cricetinae; Humans; Hydrolysis; Male; Models, Molecular; Molecular Sequence Data; Peptidyl-Dipeptidase A; Sequence Homology, Amino Acid; Sodium Chloride; Substrate Specificity; Testis | 2003 |
Localization of carboxypeptidase A-like enzyme in rat kidney.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxypeptidases A; Kidney; Peptide Fragments; Peptides; Rats | 2003 |
Protein-peptide complexes of angiotensins in the mechanisms of thirst motivation.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Captopril; Drinking Behavior; Drug Combinations; Instinct; Male; Rats; Rats, Wistar; Serum Albumin, Bovine; Thirst; Time Factors | 2003 |
Stenosis progression after surgical injury in Milan hypertensive rat carotid arteries.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Carotid Arteries; Carotid Stenosis; Disease Progression; Gene Expression; Genes, fos; Genes, jun; Genes, myc; Hypertension; Models, Animal; Rats; Rats, Inbred Strains; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 2003 |
Application of molecular beam deflection time-of-flight mass spectrometry to peptide analysis.
Topics: Algorithms; Amino Acid Sequence; Amino Acids, Neutral; Angiotensin I; Angiotensin II; Dipeptides; Electrochemistry; Gramicidin; Luteinizing Hormone; Mass Spectrometry; Molecular Sequence Data; Molecular Weight; Peptides; Protein Conformation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2003 |
Identification of angiotensin I in several vertebrate species: its structural and functional evolution.
Topics: Ambystoma; Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chromatography; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Dromaiidae; Eels; Evolution, Molecular; Kidney; Lampreys; Mass Spectrometry; Sequence Homology, Amino Acid; Tissue Extracts; Vertebrates | 2004 |
Angiotensin-(1-7) modulates vascular resistance and sympathetic neurotransmission in kidneys of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Kidney; Male; Norepinephrine; Organ Culture Techniques; Peptide Fragments; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Stimulation, Chemical; Sympathetic Nervous System; Vascular Resistance | 2004 |
The role of bradykinin, AT2 and angiotensin 1-7 receptors in the EDRF-dependent vasodilator effect of angiotensin II on the isolated mesenteric vascular bed of the rat.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Endothelium-Dependent Relaxing Factors; In Vitro Techniques; Male; Mesenteric Arteries; Mesenteric Veins; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation | 2004 |
Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Bradykinin; Hypertension; Hypothalamus; Imidazoles; In Vitro Techniques; Nitric Oxide; Norepinephrine; Peptide Fragments; Potassium; Pyridines; Rats; Rats, Wistar | 2004 |
Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Brain; Enzyme Induction; Female; Kidney; Lisinopril; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A | 2004 |
A short synthetic peptide inhibits signal transduction, migration and angiogenesis mediated by Tie2 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Binding, Competitive; Biological Assay; Cell Movement; Cells, Cultured; Chick Embryo; Consensus Sequence; Endothelial Cells; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Physiologic; Oligopeptides; Peptide Library; Receptor, TIE-2; Signal Transduction; Umbilical Veins; Vascular Endothelial Growth Factor A | 2004 |
Depletion of tissue angiotensin-converting enzyme differentially influences the intrarenal and urinary expression of angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Carboxypeptidases; Diuresis; Gene Expression Regulation; Hypotension; Kidney; Mice; Mice, Knockout; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Polyuria; Renin-Angiotensin System; RNA, Messenger | 2004 |
Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Cardiomyopathy, Hypertrophic; Coronary Vessels; Disease Models, Animal; Enzyme Induction; Imidazoles; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Ventricular Remodeling | 2004 |
Sub-second isoelectric focusing in free flow using a microfluidic device.
Topics: Angiotensin I; Angiotensin II; Hydrogen-Ion Concentration; Insulin-Like Growth Factor I; Isoelectric Focusing; Microcomputers; Nanotechnology; Peptides | 2003 |
Improved PSD and CID on a MALDI TOFMS.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Calibration; Electrochemistry; Ions; Peptides; Reference Values; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substance P | 2004 |
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats.
Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine | 2004 |
Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Captopril; Drug Synergism; Hypertension; Infusions, Intra-Arterial; Infusions, Intravenous; Male; Peptide Fragments; Rats; Rats, Wistar | 2004 |
Increased ACE 2 and decreased ACE protein in renal tubules from diabetic mice: a renoprotective combination?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Carboxypeptidases; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Induction; Kidney Tubules; Lipids; Lung; Membrane Proteins; Mice; Myocardium; Organ Size; Organ Specificity; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger | 2004 |
A genetic variant of ACE increases cell survival: a new paradigm for biology and disease.
Topics: Alu Elements; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Base Sequence; Captopril; Cell Survival; Cells, Cultured; Endothelial Cells; Fluorescent Antibody Technique; Gene Expression Profiling; Humans; Isoenzymes; Molecular Sequence Data; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Sequence Analysis, DNA | 2004 |
Localization of components of the renin-angiotensin system in the suprachiasmatic nucleus of normotensive Sprague-Dawley rats: part A. angiotensin I/II, a light and electron microscopic study.
Topics: Angiotensin I; Angiotensin II; Animals; Axons; Biological Transport, Active; Blood Vessels; Cell Nucleus; Cytosol; Dendrites; Endothelial Cells; Immunohistochemistry; Microscopy, Electron; Neurons; Neuropil; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Subcellular Fractions; Suprachiasmatic Nucleus; Synapses | 2004 |
Angiotensin administration stimulates renal 11 beta-hydroxysteroid dehydrogenase activity in healthy men.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adult; Angiotensin I; Angiotensin II; Cortisone; Humans; Hydrocortisone; Kidney; Male | 2004 |
Angiotensin-converting enzyme inhibition studies by natural leech inhibitors by capillary electrophoresis and competition assay.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Electrophoresis, Capillary; Leeches; Neurons; Neuropeptides; Oligopeptides; Peptidyl-Dipeptidase A | 2004 |
Angiotensin II stimulates nitric oxide production in pulmonary artery endothelium via the type 2 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cattle; Cells, Cultured; Dithiothreitol; Dose-Response Relationship, Drug; Endothelium, Vascular; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Pulmonary Artery; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Vasoconstriction; Vasoconstrictor Agents | 2004 |
Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Animals; Carboxypeptidases A; Cells, Cultured; Chromatography, High Pressure Liquid; Chymases; Enzyme-Linked Immunosorbent Assay; Heparin; Humans; Kinetics; Mast Cells; Mice; Mice, Inbred C57BL; Models, Biological; Molecular Sequence Data; Peritoneum; Serine Endopeptidases; Time Factors; Transgenes | 2004 |
Angiotensin II and angiotensin-(1-7) inhibit the inner cortex Na+ -ATPase activity through AT2 receptor.
Topics: Adjuvants, Immunologic; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Cholera Toxin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Imidazoles; Kidney Cortex; Losartan; Peptide Fragments; Pertussis Toxin; Pyridines; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase; Swine; Vasoconstrictor Agents | 2004 |
Raised prorenin and renin concentrations in pre-eclamptic placentae when measured after acid activation.
Topics: Adult; Amnion; Angiotensin I; Angiotensin II; Chorion; Female; Humans; Placenta; Pre-Eclampsia; Pregnancy; Renin | 2004 |
Differential response of human cardiac fibroblasts to angiotensin I and angiotensin II.
Topics: Angiotensin I; Angiotensin II; Captopril; Cell Line; Collagen; Fibroblasts; Humans; Losartan; Myocardium; Peptidyl-Dipeptidase A | 2004 |
TP receptors regulate renal hemodynamics during angiotensin II slow pressor response.
Topics: 6-Ketoprostaglandin F1 alpha; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Body Weight; Dinoprost; Electrolytes; Epoprostenol; Female; Heart Rate; Hematocrit; Hypertension, Renal; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrates; Nitrites; Organ Size; Receptor, Angiotensin, Type 1; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Specific Pathogen-Free Organisms; Thiobarbituric Acid Reactive Substances; Thromboxane B2; Urine; Vascular Resistance; Vasoconstrictor Agents | 2004 |
The renin angiotensin system in childhood hypertension: selective increase of angiotensin-(1-7) in essential hypertension.
Topics: Adolescent; Angiotensin I; Angiotensin II; Calcium Channel Blockers; Case-Control Studies; Child; Child, Preschool; Female; Humans; Hypertension; Male; Peptide Fragments; Renin; Renin-Angiotensin System | 2004 |
Tandem time-of-flight mass spectrometer for photodissociation of biopolymer ions generated by matrix-assisted laser desorption ionization (MALDI-TOF-PD-TOF) using a linear-plus-quadratic potential reflectron.
Topics: Angiotensin I; Angiotensin II; Biopolymers; Bradykinin; Nanotechnology; Peptide Fragments; Photochemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vasoconstrictor Agents | 2004 |
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Binding Sites; Carboxypeptidases; CHO Cells; Cricetinae; Cricetulus; Humans; Hydrolysis; Kinetics; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Substrate Specificity | 2004 |
Intracellular and extracellular angiotensin II enhance the L-type calcium current in the failing heart.
Topics: Adenosine Triphosphatases; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Calcium Channels, L-Type; Calcium Signaling; Cardiomyopathies; Cells, Cultured; Cricetinae; Enalaprilat; Enzyme Activation; Extracellular Fluid; Intracellular Fluid; Losartan; Male; Mesocricetus; Myocytes, Cardiac; Protein Kinase C; Sarcoplasmic Reticulum; Staurosporine; Thapsigargin | 2004 |
Insulin stimulates endogenous angiotensin II production via a mitogen-activated protein kinase pathway in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta; Cell Division; Cells, Cultured; Cytosol; Enzyme Inhibitors; Flavonoids; Hypoglycemic Agents; Immunohistochemistry; Insulin; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2004 |
Transport of angiotensin peptides across the Caco-2 monolayer.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Biological Transport, Active; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; Diffusion; Humans; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Structure-Activity Relationship | 2004 |
Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Carboxypeptidases; Cardiac Output, Low; Case-Control Studies; Coronary Circulation; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A | 2004 |
Angiotensin II receptor modulation of renal vascular resistance and neurotransmission in young and adult spontaneously hypertensive rats.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WF; Receptor, Angiotensin, Type 1; Signal Transduction; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstrictor Agents | 2005 |
The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Kidney Tubules, Proximal; Male; Mass Spectrometry; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger | 2005 |
Tissue distribution of antihypertensive dipeptide, Val-Tyr, after its single oral administration to spontaneously hypertensive rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dipeptides; Hypertension; Rats; Rats, Inbred SHR; Tissue Distribution | 2004 |
Inhibition of diabetic nephropathy by a decoy peptide corresponding to the "handle" region for nonproteolytic activation of prorenin.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Kidney; Peptides; Protein Conformation; Protein Precursors; Protein Structure, Tertiary; Rats; Renin; Renin-Angiotensin System; Urine | 2004 |
Chemiluminescence detection of arginine-containing peptides separated with monolithic high-performance liquid chromatography.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Arginine; Bradykinin; Chromatography, High Pressure Liquid; Luminescent Measurements; Peptides | 2005 |
Chronic infusion of angiotensin-(1-7) reduces heart angiotensin II levels in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; DNA Primers; Male; Myocardium; Peptide Fragments; Peptides; Polymerase Chain Reaction; Protein Structure, Tertiary; Radioimmunoassay; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2005 |
Low sodium diet inhibits the local counter-regulator effect of angiotensin-(1-7) on angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Diet, Sodium-Restricted; Endothelium, Vascular; In Vitro Techniques; Male; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction | 2004 |
Angiotensin II modulates frizzled-2 receptor expression in rat vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Base Sequence; Cells, Cultured; Drosophila Proteins; Drug Implants; Frizzled Receptors; Gene Expression Regulation; Intercellular Signaling Peptides and Proteins; Male; Molecular Sequence Data; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Receptors, Neurotransmitter; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Time Factors; Transforming Growth Factor beta; Wnt Proteins | 2005 |
Pharmacological concentration of angiotensin-(1-7) activates NADPH oxidase after ischemia-reperfusion in rat heart through AT1 receptor stimulation.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Enzyme Activation; Heart; In Vitro Techniques; Losartan; Male; Myocardial Ischemia; Myocardium; NADPH Oxidases; Peptide Fragments; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Reperfusion | 2005 |
Pressor and intra-renal effects of angiotensins I and II, and noradrenaline, in anaesthetized and conscious sheep. The effects of halothane anaesthesia on pressor sensitivity and electrolyte shifts: the proposed use of angiotensin I in treating septicaemi
Topics: Angiotensin I; Angiotensin II; Animals; Electrolytes; Halothane; Kidney; Norepinephrine; Sepsis; Sheep; Shock, Septic | 2005 |
A novel mechanism for angiotensin II formation in streptozotocin-diabetic rat glomeruli.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Glucose; Body Weight; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Kidney Glomerulus; Male; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2005 |
Mast cells: the missing source of cardiac renin?
Topics: Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Humans; Mast Cells; Myocardium; Rats; Renin; Renin-Angiotensin System | 2005 |
Mast cell chymase in the ischemic kidney of severe unilateral renovascular hypertension.
Topics: Angiography, Digital Subtraction; Angiotensin I; Angiotensin II; Arteriosclerosis; Captopril; Chymases; Female; Humans; Hyperaldosteronism; Hypertension, Renovascular; Ischemia; Kidney; Mast Cells; Middle Aged; Nephrectomy; Renal Artery; Renal Artery Obstruction; Renal Veins; Renin; Renin-Angiotensin System; Serine Endopeptidases; Smoking | 2005 |
Effects of angiotensin-(1-7) blockade on renal function in rats with enhanced intrarenal Ang II activity.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Diuresis; Glomerular Filtration Rate; Kidney; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 2005 |
Effect of bestatin on angiotensin I-, II- and III-induced collagen gel contraction in cardiac fibroblasts.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Anilides; Animals; Cells, Cultured; Collagen; DNA; Fibroblasts; Gels; Hydrolysis; Leucine; Male; Myocardium; Nitro Compounds; Rats; Rats, Wistar; Thymidine | 2004 |
Cardiovascular effects of angiotensin II and angiotensin-(1-7) at the RVLM of trained normotensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Wistar | 2005 |
Angiotensin II AT1 receptors regulate ACE2 and angiotensin-(1-7) expression in the aorta of spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Atenolol; Carboxypeptidases; Carotid Arteries; Gene Expression Regulation, Enzymologic; Hydralazine; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; RNA, Messenger; Tetrazoles; Vasodilator Agents | 2005 |
Expression of components of the renin-angiotensin system in autosomal recessive polycystic kidney disease.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Female; Humans; Immunohistochemistry; Infant; Infant, Newborn; Kidney; Kidney Tubules; Polycystic Kidney, Autosomal Recessive; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2005 |
Angiotensin-cleaving catalysts: conversion of N-terminal aspartate to pyruvate through oxidative decarboxylation catalyzed by Co(III)cyclen.
Topics: Angiotensin I; Angiotensin II; Catalysis; Decarboxylation; Drug Design; Humans; Oligopeptides; Organometallic Compounds; Oxidation-Reduction | 2005 |
Chronic administration of angiotensin-(1-7) attenuates pressure-overload left ventricular hypertrophy and fibrosis in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aortic Coarctation; Blood Pressure; Fibrosis; Hypertrophy, Left Ventricular; Male; Myocardium; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Ventricular Function, Left | 2005 |
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Gene Expression Regulation; Lisinopril; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; RNA, Messenger | 2005 |
Des-aspartate-angiotensin I and angiotensin AT1 receptors in rat cardiac ventricles.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Heart Ventricles; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2005 |
Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats.
Topics: Angiotensin Amide; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Vessels; Diabetes Mellitus, Experimental; Kidney; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Splanchnic Circulation; Vasoconstrictor Agents | 2005 |
[Angiotensin-(1-7) modulates fibrinolytic imbalance induced by oxidized low-density lipoprotein in cultured human umbilical vein endothelial cells].
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Cells, Cultured; Endothelium, Vascular; Humans; Lipoproteins, LDL; Peptide Fragments; Plasminogen Activator Inhibitor 1; Tissue Plasminogen Activator; Umbilical Veins | 2005 |
Mechanical unloading during left ventricular assist device support increases left ventricular collagen cross-linking and myocardial stiffness.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Cardiomyopathy, Dilated; Collagen; Female; Heart-Assist Devices; Humans; Immunohistochemistry; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 9; Middle Aged; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Tissue Inhibitor of Metalloproteinase-1; Ventricular Function, Left | 2005 |
NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria.
Topics: Adenoviridae; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Carboxypeptidases; Dietary Proteins; Female; I-kappa B Proteins; Kidney; NF-kappa B; NF-KappaB Inhibitor alpha; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; RNA, Messenger | 2005 |
Infusion of angiotensin II reduces loss of glomerular capillary area in the early phase of anti-Thy-1.1 nephritis possibly via regulating angiogenesis-associated factors.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Capillaries; Glomerulonephritis; Hypertension, Renal; Immunohistochemistry; Isoantibodies; Kidney Glomerulus; Macrophages; Male; Monocytes; Neovascularization, Physiologic; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, TIE-2; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vasoconstrictor Agents | 2005 |
Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Imidazoles; Kidney; Microinjections; Muscimol; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System | 2005 |
Dynamic pH junction technique for on-line preconcentration of peptides in capillary electrophoresis.
Topics: Angiotensin I; Angiotensin II; Buffers; Electrophoresis, Capillary; Flow Injection Analysis; Hydrogen-Ion Concentration; Peptides | 2005 |
Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cachexia; Cell Culture Techniques; Imidazolidines; Male; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Neoplasms; Proteasome Endopeptidase Complex; Ubiquitin | 2005 |
Role of blood pressure reduction in prevention of cardiac and vascular hypertrophy.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiomegaly; Collagen; Disease Progression; Endothelium, Vascular; Heart Rate; Hypertension; Imidazoles; Male; Mesenteric Arteries; Myocardium; Rats; Rats, Inbred SHR; Tetrazoles; Vascular Diseases; Vascular Resistance | 2005 |
Short-term angiotensin(1-7) receptor MAS stimulation improves endothelial function in normotensive rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reference Values; Vasodilator Agents | 2005 |
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Chromatography; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; gamma-Aminobutyric Acid; Imidazoles; Male; Microdialysis; NG-Nitroarginine Methyl Ester; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Sulfonic Acids; Tetrazoles; Time Factors | 2005 |
Adrenal angiotensin: origin and site of generation.
Topics: Acrylates; Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Chromatography, High Pressure Liquid; Female; Imidazoles; Infusions, Intra-Arterial; Iodine Radioisotopes; Male; Models, Biological; Renin-Angiotensin System; Swine; Thiophenes | 2005 |
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Role of chymase-dependent angiotensin II formation in regulating blood pressure in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Body Weight; Chymases; Gene Expression Regulation, Enzymologic; Hypertension; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Serine Endopeptidases; Vasoconstriction | 2005 |
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Drug Synergism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents | 2005 |
Angiotensin-(1-7) enhances anti-aggregatory effects of the nitric oxide donor sodium nitroprusside.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Angiotensin I; Angiotensin II; Antihypertensive Agents; Coronary Disease; Drug Synergism; Female; Humans; Male; Myocardial Infarction; Nitric Oxide Donors; Nitroprusside; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Vasoconstrictor Agents | 2005 |
Role of elastase-2 as an angiotensin II-forming enzyme in rat carotid artery.
Topics: Amino Acid Chloromethyl Ketones; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Captopril; Carotid Artery, Common; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Oligopeptides; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine Endopeptidases; Serine Proteinase Inhibitors; Vasoconstriction | 2005 |
Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Astrocytes; Carboxypeptidases; Cells, Cultured; Cerebellum; Female; Gene Expression Regulation; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents | 2006 |
Effects of renin-angiotensin system blockade on renal angiotensin-(1-7) forming enzymes and receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Gene Expression Regulation, Enzymologic; Hypertension, Renal; Kidney; Lisinopril; Losartan; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Receptors, Angiotensin; Renin-Angiotensin System | 2005 |
Nephron function in transgenic mice with selective vascular or tubular expression of Angiotensin-converting enzyme.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Pressure Determination; Disease Models, Animal; Female; Glomerular Filtration Rate; Immunohistochemistry; Injections, Intravenous; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Nephrons; Peptidyl-Dipeptidase A; Species Specificity | 2005 |
Effect of hypertension on angiotensin-(1-7) levels in rats with different angiotensin-I converting enzyme polymorphism.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Genotype; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Rats; Rats, Inbred Lew; Rats, Mutant Strains | 2006 |
Antiproliferative action of an angiotensin I-converting enzyme inhibitory peptide, Val-Tyr, via an L-type Ca2+ channel inhibition in cultured vascular smooth muscle cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Division; Cells, Cultured; Cytoskeletal Proteins; Dipeptides; Humans; Muscle, Smooth, Vascular; Paxillin; Phosphoproteins; Potassium Channel Blockers; Vasoconstrictor Agents | 2005 |
Ultra-rapid separation of an angiotensin mixture in nanochannels using shear-driven chromatography.
Topics: Angiotensin I; Angiotensin II; Chromatography, Liquid; Nanotechnology | 2006 |
Mechanism of induction of muscle protein degradation by angiotensin II.
Topics: Active Transport, Cell Nucleus; Angiotensin I; Angiotensin II; Animals; Blood Proteins; Cell Line; Enzyme Activation; I-kappa B Kinase; Luciferases; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Naphthalenes; NF-kappa B; Proteasome Endopeptidase Complex; Protein Kinase C; Proteoglycans; Resveratrol; Signal Transduction; Stilbenes; Transcriptional Activation | 2006 |
Baroreflex modulation by angiotensins at the rat rostral and caudal ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Animals; Baroreflex; Blood Pressure; Heart Rate; Male; Medulla Oblongata; Microinjections; Models, Biological; Nitric Oxide Synthase Type I; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System; Sympathetic Nervous System | 2006 |
Determinants of increased angiotensin II levels in severe chronic heart failure patients despite ACE inhibition.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Feedback, Physiological; Female; Heart Failure; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Spironolactone | 2006 |
High-performance SPME/AP MALDI system for high-throughput sampling and determination of peptides.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Peptides; Polymers; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Microextraction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Pathways of glomerular toxicity of cyclosporine-A: an "in vitro" study.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin-1; Female; Kidney Glomerulus; Oligopeptides; Organ Culture Techniques; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors | 2005 |
Differential expression of nuclear AT1 receptors and angiotensin II within the kidney of the male congenic mRen2. Lewis rat.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Animals, Genetically Modified; Cell Membrane; Cell Nucleus; Crosses, Genetic; Heterozygote; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Mice; Rats; Rats, Inbred Lew; Receptor, Angiotensin, Type 1; Renin | 2006 |
High glucose increases extracellular matrix production in pancreatic stellate cells by activating the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Collagen; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Extracellular Matrix; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Glucose; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Male; Pancreas; Pancreatitis; Ramipril; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta | 2006 |
Changes in vascular leakage and expression of angiopoietins in the corpus luteum during pregnancy in rats.
Topics: Angiopoietins; Angiotensin I; Angiotensin II; Animals; Blood Vessels; Contrast Media; Corpus Luteum; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Female; Immunohistochemistry; Microscopy, Fluorescence; Neovascularization, Physiologic; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor, TIE-2; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA, Messenger | 2006 |
Are multiple angiotensin receptor types involved in angiotensin (1-7) actions on isolated rat portal vein.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Portal Vein; Rats; Receptors, Angiotensin | 2005 |
Does angiotensin (1-7) contribute to the anti-proteinuric effect of ACE-inhibitors.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibiotics, Antineoplastic; Blood Pressure; Body Weight; Creatine; Creatinine; Doxorubicin; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Wistar | 2005 |
Localized accumulation of angiotensin II and production of angiotensin-(1-7) in rat luteal cells and effects on steroidogenesis.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Female; Luteal Cells; Peptide Fragments; Rats; Signal Transduction; Steroids; Subcellular Fractions; Tissue Distribution | 2006 |
Renin-angiotensin system is an important factor in hormone refractory prostate cancer.
Topics: Androgen Antagonists; Angiotensin I; Angiotensin II; Antineoplastic Agents, Hormonal; Blotting, Western; Cell Line, Tumor; Dexamethasone; Dihydrotestosterone; Drug Resistance, Neoplasm; Estradiol; Gene Expression Regulation, Neoplastic; Humans; Male; Peptidyl-Dipeptidase A; Prostate; Prostatic Neoplasms; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2006 |
Pressor responses to alligator Angiotensin I and some analogs in the spectacled caiman (Caiman crocodilus).
Topics: Alligators and Crocodiles; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Epinephrine; Losartan; Male; Norepinephrine | 2006 |
Escherichia coli lipopolysaccharide inhibits renin activity in human mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Blotting, Western; Cell Line; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Endotoxemia; Escherichia coli; Humans; Lipopolysaccharides; Mesangial Cells; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System; Time Factors | 2006 |
Mechanisms of apoptosis after ischemia and reperfusion: role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Shape; fas Receptor; Female; Heart; Myocardial Infarction; Myocardium; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Random Allocation; Renin-Angiotensin System; Reperfusion Injury; Swine; Tetrahydroisoquinolines; Tumor Suppressor Protein p53 | 2006 |
Angiotensin II production and distribution in the kidney--II. Model-based analysis of experimental data.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Vessels; Kidney; Kinetics; Models, Biological; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation; Renin-Angiotensin System; Swine | 2006 |
Central and peripheral renin-angiotensin systems in ouabain-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cardiotonic Agents; Central Nervous System; Heart; Heart Rate; Hypertension; Kidney; Male; Ouabain; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Peripheral Nervous System; Preoptic Area; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subfornical Organ | 2006 |
Cardioprotective effects of rosiglitazone are associated with selective overexpression of type 2 angiotensin receptors and inhibition of p42/44 MAPK.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cardiotonic Agents; Enzyme Inhibitors; Hemodynamics; Hypoglycemic Agents; Immunohistochemistry; Ligands; Male; Mitogen-Activated Protein Kinase 1; Myocardial Infarction; Myocardium; PPAR gamma; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones | 2006 |
Angiotensin-(1-7) inhibits angiotensin II-stimulated phosphorylation of MAP kinases in proximal tubular cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; JNK Mitogen-Activated Protein Kinases; Kidney Tubules, Proximal; Male; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Specific receptor for angiotensinogen on human renal cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Binding, Competitive; Cells, Cultured; Epithelial Cells; Humans; Iodine Radioisotopes; Kidney Tubules; Receptors, Angiotensin; Time Factors | 2006 |
Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Congenic; Animals, Genetically Modified; Crosses, Genetic; Hypertension, Renal; Kinetics; Lisinopril; Losartan; Male; Models, Genetic; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Time Factors | 2006 |
Renal Angiotensin receptor type 1 and 2 upregulation in intrauterine growth restriction of newborn piglets.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Birth Weight; Female; Fetal Growth Retardation; Kidney; Kidney Cortex; Kidney Medulla; Reference Values; Renin-Angiotensin System; Swine; Up-Regulation | 2006 |
ACE and ACE2: their role to balance the expression of angiotensin II and angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Strains | 2006 |
The role of angiotensin(1-7) in renal vasculature of the rat.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; In Vitro Techniques; Kidney Glomerulus; Male; Peptide Fragments; Rats; Rats, Wistar; Renal Artery; Renal Circulation; Vasoconstrictor Agents | 2006 |
A case of Gitelman's syndrome with decreased angiotensin II-forming activity.
Topics: Adult; Angiotensin I; Angiotensin II; Bartter Syndrome; DNA; Glomerulonephritis; Humans; Hyperaldosteronism; Leukocytes; Lymphocytes; Male; Receptors, Drug; Renin; Renin-Angiotensin System; Solute Carrier Family 12, Member 3; Symporters | 2006 |
Endothelium-derived steroidogenic factor enhances angiotensin II-stimulated aldosterone release by bovine zona glomerulosa cells.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Animals; Cattle; Cells, Cultured; Culture Media, Conditioned; Endothelium; Iodine Radioisotopes; Peptide Fragments; Peptides; Vasoconstrictor Agents; Zona Glomerulosa | 2007 |
Effects of genetic deletion of angiotensin-(1-7) receptor Mas on cardiac function during ischemia/reperfusion in the isolated perfused mouse heart.
Topics: Angiotensin I; Angiotensin II; Animals; Diastole; Mice; Mice, Knockout; Myocardial Ischemia; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Reperfusion; Systole | 2006 |
Circulating renin Angiotensin system in childhood chronic renal failure: marked increase of Angiotensin-(1-7) in end-stage renal disease.
Topics: Adolescent; Angiotensin I; Angiotensin II; Angiotensins; Case-Control Studies; Child; Child, Preschool; Cross-Sectional Studies; Disease Progression; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2006 |
Influence of gender and genetic variability on plasma angiotensin peptides.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Female; Genotype; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Sex Factors | 2006 |
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7).
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart; Hypertension; Male; Myocardium; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Time Factors; Transforming Growth Factor beta; Ventricular Remodeling | 2007 |
Evidence for a new angiotensin-(1-7) receptor subtype in the aorta of Sprague-Dawley rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation | 2007 |
Apoptosis and proliferation of mesangial cells isolated from kidneys undergoing compensatory growth following contralateral nephrectomy: role of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Bradykinin; Captopril; Cell Proliferation; Cell Separation; Cells, Cultured; Gene Expression Regulation; Mesangial Cells; Nephrectomy; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger | 2007 |
The renin-angiotensin system in a rat model of hepatic fibrosis: evidence for a protective role of Angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cytoprotection; Hydroxyproline; Liver; Liver Cirrhosis; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Transforming Growth Factor beta1 | 2007 |
Differential sympathetic and angiotensinergic responses in rats submitted to low- or high-salt diet.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Gene Expression Regulation; Hypertension; Kidney; Male; Rats; Rats, Wistar; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium Chloride, Dietary; Sympathetic Nervous System | 2007 |
Regulation of angiotensin II receptors levels during rat induced pulpitis.
Topics: Angiotensin I; Angiotensin II; Animals; Dental Pulp; Inflammation; Male; Pulpitis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2007 |
Angiotensin-(1-7) potentiates responses to bradykinin but does not change responses to angiotensin I.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Carotid Artery, External; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enalaprilat; Male; Meclofenamic Acid; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
The pregnancy-induced increase of plasma angiotensin-(1-7) is blunted in gestational diabetes.
Topics: Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Diabetes, Gestational; Female; Gestational Age; Humans; Peptide Fragments; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Radioimmunoassay; Renin-Angiotensin System | 2007 |
Effector peptides of the renin-angiotensin system in the central mechanisms of acquired and innate behavior in thirst in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Behavior, Animal; Drinking; Instinct; Male; Peptides; Rats; Rats, Wistar; Renin-Angiotensin System; Thirst; Time Factors | 2007 |
Identification of a novel non-AT1, non-AT2 angiotensin binding site in the rat brain.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Autoradiography; Binding, Competitive; Brain; Drug Interactions; Imidazoles; Iodine Isotopes; Losartan; p-Chloromercuribenzoic Acid; Pyridines; Rats; Rats, Sprague-Dawley | 2007 |
Primary role of angiotensin-converting enzyme-2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Cardiomegaly; Disease Models, Animal; Half-Life; Hypertension; Imidazoles; Kinetics; Leucine; Male; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin | 2007 |
Effects of angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; Nitric Oxide; Peptide Fragments; Prostaglandins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Renal Circulation; Splanchnic Circulation; Streptozocin | 2007 |
Olmesartan is an angiotensin II receptor blocker with an inhibitory effect on angiotensin-converting enzyme.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Gene Expression; Imidazoles; Male; Myocardium; Nitrates; Nitrites; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Tetrazoles; Ventricular Remodeling | 2006 |
Angiotensin-(3-7) pressor effect at the rostral ventrolateral medulla.
Topics: Anesthetics, Intravenous; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Pulsatile Flow; Rats; Rats, Wistar; Urethane | 2007 |
Reduced circulating levels of angiotensin-(1--7) in systemic sclerosis: a new pathway in the dysregulation of endothelial-dependent vascular tone control.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Epoprostenol; Female; Humans; Male; Middle Aged; Neprilysin; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Scleroderma, Systemic; Vasoconstrictor Agents | 2007 |
A 90-day subchronic toxicity study and reproductive toxicity studies on ACE-inhibiting lactotripeptide.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Blood Glucose; Chlorides; Cholesterol; Female; Fetal Development; Kidney; Male; Oligopeptides; Potassium; Rabbits; Random Allocation; Rats; Rats, Wistar; Reproduction; Sodium; Specific Pathogen-Free Organisms; Statistics, Nonparametric; Toxicity Tests, Chronic | 2007 |
Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletion/deletion genotype.
Topics: Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Female; Gene Deletion; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System | 2007 |
Evaluation of angiotensin converting enzyme (ACE)-like activity of acellular hemoglobin.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Enzyme-Linked Immunosorbent Assay; Hemoglobins; Humans; Hydrogen Peroxide; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Spectrophotometry; Substrate Specificity; Vasoconstriction | 2007 |
Ab initio study of non-peptidic antihypertensives.
Topics: Angiotensin I; Angiotensin II; Antihypertensive Agents; Computational Biology; Computer Simulation; Inhibitory Concentration 50; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptides; Static Electricity; Structure-Activity Relationship; Substrate Specificity | 2007 |
Association of somatic and N-domain angiotensin-converting enzymes from Wistar rat tissue with renal dysfunction in diabetes mellitus.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Hypoglycemic Agents; Insulin; Kidney; Male; Molecular Weight; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Structure, Tertiary; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Slowly progressive, angiotensin II-independent glomerulosclerosis in human (pro)renin receptor-transgenic rats.
Topics: Age Factors; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Chlorocebus aethiops; COS Cells; Disease Progression; Glomerulosclerosis, Focal Segmental; Humans; MAP Kinase Signaling System; Prorenin Receptor; Proteinuria; Rats; Receptors, Cell Surface; Transforming Growth Factor beta1 | 2007 |
Angiotensin-(1 7) stimulates the phosphorylation of JAK2, IRS-1 and Akt in rat heart in vivo: role of the AT1 and Mas receptors.
Topics: Androstadienes; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Insulin; Insulin Receptor Substrate Proteins; Janus Kinase 2; Losartan; Male; Myocardium; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Tyrphostins; Wortmannin | 2007 |
On the mechanism of coronary vasodilation induced by angiotensin-(1-7) in the isolated guinea pig heart.
Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Bradykinin; Coronary Vessels; Dose-Response Relationship, Drug; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Vasodilation | 2007 |
The association between angiotensin II-induced free radical generation and membrane fluidity in neutrophils of patients with metabolic syndrome.
Topics: Adult; Angiotensin I; Angiotensin II; Anticholesteremic Agents; Cholesterol; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Female; Fluvastatin; Homeostasis; Humans; Hypercholesterolemia; Indoles; Leukotriene C4; Male; Membrane Fluidity; Metabolic Syndrome; Middle Aged; Neutrophils; Pertussis Toxin; Protein Prenylation; Quinacrine; Signal Transduction; Superoxides; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2006 |
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.
Topics: Acetophenones; Allopurinol; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Drug Antagonism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Onium Compounds; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxides | 2007 |
Angiotensin II and its receptor subtypes in the human retina.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Binding, Competitive; Blotting, Western; Female; Fluorescent Antibody Technique, Indirect; Humans; Male; Microscopy, Confocal; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Retina; Tissue Donors | 2007 |
Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Kidney; Rats; Rats, Inbred WKY; Renal Circulation; Renin-Angiotensin System; Sulfhydryl Compounds; Time Factors | 2007 |
Characterization of the first angiotensin-converting like enzyme in bacteria: Ancestor ACE is already active.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Bacterial Proteins; Cloning, Molecular; Computational Biology; Genome, Bacterial; Molecular Sequence Data; Peptidyl-Dipeptidase A; Phylogeny; Protein Conformation; Sequence Homology, Amino Acid; Structure-Activity Relationship; Xanthomonas axonopodis | 2007 |
Long-term AT1 receptor blockade improves metabolic function and provides renoprotection in Fischer-344 rats.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Imidazoles; Insulin; Kidney; Leptin; Male; Metabolic Syndrome; Metabolism; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles | 2007 |
Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function.
Topics: Angiotensin I; Angiotensin II; Animals; Desoxycorticosterone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Erectile Dysfunction; Hypertension; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Sodium Chloride, Dietary; Vasodilator Agents | 2007 |
Mechanism of high glucose induced angiotensin II production in rat vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cathepsin D; Cells, Cultured; Chymases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; RNA, Messenger; RNA, Small Interfering; Tissue Plasminogen Activator | 2007 |
Ovariectomy is protective against renal injury in the high-salt-fed older mRen2. Lewis rat.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Animals, Congenic; Blood Pressure; C-Reactive Protein; Cell Adhesion Molecules; Disease Models, Animal; Female; Fibrosis; Hypertension; Hypertrophy; Insulin-Like Growth Factor I; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Diseases; Membrane Proteins; Ovariectomy; Peptide Fragments; Proteinuria; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; RNA, Messenger; Sodium Chloride, Dietary | 2007 |
Increased hypothalamic angiotensin-(1-7) levels in rats with aortic coarctation-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Aortic Coarctation; Hypertension; Hypothalamus; Kidney; Male; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Renin-Angiotensin System | 2007 |
Different responses to angiotensin-(1-7) in young, aged and diabetic rabbit corpus cavernosum.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erectile Dysfunction; Large-Conductance Calcium-Activated Potassium Channels; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Penis; Peptide Fragments; Peptides; Potassium Channel Blockers; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2007 |
Antiangiogenic role of somatostatin receptor 2 in a model of hypoxia-induced neovascularization in the retina: results from transgenic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Capillaries; Disease Models, Animal; Hypoxia; Insulin-Like Growth Factor I; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Receptor, IGF Type 1; Receptor, TIE-1; Receptor, TIE-2; Receptors, Somatostatin; Retinal Diseases; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2007 |
Evidence for Mas-mediated bradykinin potentiation by the angiotensin-(1-7) nonpeptide mimic AVE 0991 in normotensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Vasodilator Agents | 2007 |
Hepatic conversion of angiotensin I and the portal hypertensive response to angiotensin II in normal and regenerating liver.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Hypertension, Portal; Kinetics; Liver; Liver Circulation; Liver Regeneration; Rats; Rats, Wistar | 2007 |
Role of endogenously secreted angiotensin II in the CO2-induced stimulation of HCO3 reabsorption by renal proximal tubules.
Topics: Absorption; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Bicarbonates; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Kidney Tubules, Proximal; Lisinopril; Peptidyl-Dipeptidase A; Rabbits; Renin-Angiotensin System | 2008 |
The progression of inflammation parallels the dermal angiogenesis in a keratin 14 IL-4-transgenic model of atopic dermatitis.
Topics: Angiotensin I; Angiotensin II; Animals; Antigens, CD; Cadherins; Cells, Cultured; Dermatitis, Atopic; Dermis; Disease Models, Animal; GTP-Binding Proteins; Interferon-gamma; Interleukin-4; Interleukin-6; Keratin-14; Keratinocytes; Mice; Mice, Transgenic; Microcirculation; Neovascularization, Pathologic; Up-Regulation; Vascular Endothelial Growth Factor A | 2008 |
ACE2 and ANG-(1-7) in the rat uterus during early and late gestation.
Topics: Amnion; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Decidua; Disease Models, Animal; Epithelial Cells; Female; Hypertension, Pregnancy-Induced; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Uterus; Yolk Sac | 2008 |
Angiotensin-(1-7) counterregulates angiotensin II signaling in human endothelial cells.
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; CSK Tyrosine-Protein Kinase; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; NADPH Oxidases; Peptide Fragments; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; src-Family Kinases | 2007 |
Endothelial dysfunction through genetic deletion or inhibition of the G protein-coupled receptor Mas: a new target to improve endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Bradykinin; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation | 2007 |
Angiotensin-(1-7) inhibits in vitro endothelial cell tube formation in human umbilical vein endothelial cells through the AT(1-7) receptor.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Imidazoles; Losartan; Neovascularization, Physiologic; Peptide Fragments; Pyridines; Receptors, Angiotensin; Umbilical Veins; Vasoconstrictor Agents | 2007 |
Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy.
Topics: Alleles; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Aorta, Abdominal; Blood Pressure; Blotting, Western; Cardiac Catheterization; Cardiomegaly; Connexin 43; DNA; Electrocardiography; Heart; Kidney; Mice; Mice, Knockout; Mice, Transgenic; Myocardium; Osmolar Concentration; Peptidyl-Dipeptidase A; Reverse Transcriptase Polymerase Chain Reaction; Tissue Distribution; Ventricular Function, Left | 2008 |
Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins.
Topics: Angiotensin I; Angiotensin II; Animals; Arrestins; Aspartic Acid Endopeptidases; beta-Arrestins; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Receptor-Like Protein; Cell Line, Tumor; Cell Membrane; Endocytosis; Endosomes; Endothelin-Converting Enzymes; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Hydrolysis; Intracellular Signaling Peptides and Proteins; Isoenzymes; Membrane Proteins; Metalloendopeptidases; Protein Binding; Protein Transport; Rats; Receptor Activity-Modifying Protein 1; Receptor Activity-Modifying Proteins; Receptor, Angiotensin, Type 1; Receptors, Calcitonin; Signal Transduction | 2007 |
Hydrolysis of various bioactive peptides by goat brain dipeptidylpeptidase-III homologue.
Topics: Adrenocorticotropic Hormone; Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Brain; Chromatography, Thin Layer; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Enkephalin, Leucine; Goats; Hydrolysis; Molecular Sequence Data; Peptides; Sequence Homology, Amino Acid; Tetragastrin | 2008 |
Role of ACE/AT2R complex in the control of mesenteric resistance artery contraction induced by ACE/AT1R complex activation in response to Ang I.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Dose-Response Relationship, Drug; Imidazoles; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Vascular Resistance; Vasoconstrictor Agents | 2008 |
Angiotensin-converting enzyme C-terminal catalytic domain is the main site of angiotensin I cleavage in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Blood Pressure; Bradykinin; Catalytic Domain; Hematocrit; Infusions, Intravenous; Kidney; Mice; Mice, Mutant Strains; Osmolar Concentration; Peptidyl-Dipeptidase A; Point Mutation; Renin; Substrate Specificity; Zinc Fingers | 2008 |
Determination of the structure of lipid vesicle-bound angiotensin II and angiotensin I.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Deuterium Exchange Measurement; Liposomes; Phospholipids; Protein Conformation; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry; Tyrosine | 2008 |
ACE2 overexpression inhibits angiotensin II-induced monocyte chemoattractant protein-1 expression in macrophages.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Cell Line; Chemokine CCL2; Gene Expression Regulation; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2008 |
Differential regulation of renal angiotensin-converting enzyme (ACE) and ACE2 during ACE inhibition and dietary sodium restriction in healthy rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Diet, Sodium-Restricted; Gene Expression Regulation, Enzymologic; Kidney; Lisinopril; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Altered regulation of renal interstitial hydrostatic pressure and the renal renin-angiotensin system in the absence of atrial natriuretic peptide.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Gene Expression Profiling; Kidney; Male; Mice; Mice, Knockout; Renin; Renin-Angiotensin System; RNA, Messenger | 2008 |
Assessment of brain AT1-receptor on the nocturnal basal and angiotensin-induced thirst and sodium appetite in ovariectomised rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensins; Animals; Antihypertensive Agents; Appetite; Brain; Circadian Rhythm; Darkness; Drinking; Estrogens; Female; Injections, Intraventricular; Losartan; Ovariectomy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sodium; Thirst | 2007 |
Antihypertensive mechanism of the dipeptide Val-Tyr in rat aorta.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Dipeptides; Dose-Response Relationship, Drug; Free Radical Scavengers; In Vitro Techniques; Lisinopril; Male; Norepinephrine; Oligopeptides; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction | 2008 |
Angiotensin-converting enzyme 2 catalytic activity in human plasma is masked by an endogenous inhibitor.
Topics: Acetonitriles; Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Antiporters; Blotting, Western; Cations, Divalent; Chelating Agents; Female; Humans; Immunoprecipitation; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Plasma; Recombinant Proteins; Subcellular Fractions | 2008 |
Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Imidazoles; Injections; Intraocular Pressure; Male; Oligopeptides; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Tonometry, Ocular; Vitreous Body | 2008 |
Hemodynamic effect produced by microinjection of angiotensins at the caudal ventrolateral medulla of spontaneously hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hemodynamics; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Regional Blood Flow; Vasoconstrictor Agents | 2008 |
Activation of local chorionic villi angiotensin II levels but not angiotensin (1-7) in preeclampsia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Chorionic Villi; Female; Gene Expression; Humans; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2008 |
Interplay of angiotensin II and angiotensin(1-7) in the regulation of matrix metalloproteinases of human cardiocytes.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Blotting, Western; Cells, Cultured; DNA; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Indicators and Reagents; Matrix Metalloproteinases; Myocytes, Cardiac; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrazoles; Tissue Inhibitor of Metalloproteinases; Transcription, Genetic; Valine; Valsartan | 2008 |
Different contributions of the angiotensin-converting enzyme C-domain and N-domain in subjects with the angiotensin-converting enzyme II and DD genotype.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Vessels; Enzyme Activation; Female; Genotype; Humans; In Vitro Techniques; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Phosphinic Acids; Point Mutation; Protein Structure, Tertiary; Sus scrofa; Tetrahydroisoquinolines; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
In vitro effect of cyclosporine-A on angiotensins secretion by glomerular cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Female; Immunosuppressive Agents; Kidney Glomerulus; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors; Tissue Culture Techniques; Up-Regulation | 2008 |
Modulation of reflex function by endogenous angiotensins in older transgenic rats with low glial angiotensinogen.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Baroreflex; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Heart Rate; Male; Neuroglia; Peptide Fragments; Rats; Renin-Angiotensin System; Solitary Nucleus; Tetrazoles | 2008 |
Distinct roles for angiotensin-converting enzyme 2 and carboxypeptidase A in the processing of angiotensins within the murine heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Carboxypeptidases A; Cell Proliferation; Fibrosis; Heart; Imidazoles; Immunohistochemistry; Leucine; Male; Membranes; Mice; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Protease Inhibitors; Succinates | 2008 |
Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Disease Models, Animal; Hypertension; Male; Myocardium; Peptide Fragments; Perfusion; Rats; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Time Factors | 2008 |
The periphery of the human fetal adrenal gland is a site of angiogenesis: zonal differential expression and regulation of angiogenic factors.
Topics: Adrenal Glands; Angiogenic Proteins; Angiotensin I; Angiotensin II; Cell Differentiation; Cells, Cultured; Endothelial Cells; Female; Fetus; Fibroblast Growth Factor 2; Gene Expression Regulation, Developmental; Gestational Age; Humans; Models, Biological; Neovascularization, Physiologic; Pregnancy; RNA, Messenger; Tissue Distribution; Vascular Endothelial Growth Factor A | 2008 |
Comparative expression analysis of the renin-angiotensin system components between white and brown perivascular adipose tissue.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Angiotensin I; Angiotensin II; Animals; Ion Channels; Male; Mitochondrial Proteins; Peptidyl-Dipeptidase A; Prorenin Receptor; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Cell Surface; Renin-Angiotensin System; RNA, Messenger; Uncoupling Protein 1 | 2008 |
Overexpression of ACE2 enhances plaque stability in a rabbit model of atherosclerosis.
Topics: Adenoviridae; Angioplasty, Balloon; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Atherosclerosis; Cell Line; Cells, Cultured; Collagen; Diet, Atherogenic; Dietary Fats; Disease Models, Animal; Disease Progression; Genetic Vectors; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled; Time Factors; Transduction, Genetic; Up-Regulation | 2008 |
Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Hypertension, Renovascular; Immunohistochemistry; Juxtaglomerular Apparatus; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Surgical Instruments; Up-Regulation; Vasoconstrictor Agents | 2008 |
A brief history of renin.
Topics: Angiotensin I; Angiotensin II; Animals; History, 19th Century; History, 20th Century; Humans; Mice; Peptidyl-Dipeptidase A; Rabbits; Renin | 2008 |
Angiotensin-(1-7) has a dual role on growth-promoting signalling pathways in rat heart in vivo by stimulating STAT3 and STAT5a/b phosphorylation and inhibiting angiotensin II-stimulated ERK1/2 and Rho kinase activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Dose-Response Relationship, Drug; Growth; Heart; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Phosphorylation; Rats; Receptor, Angiotensin, Type 1; rho-Associated Kinases; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Tyrosine | 2008 |
Sex differences in circulating and renal angiotensins of hypertensive mRen(2). Lewis but not normotensive Lewis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Angiotensins; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Female; Hypertension; Kidney; Male; Mice; Myocardium; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Factors | 2008 |
Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Baroreflex; Biguanides; Blood Pressure; Female; Heart Rate; Male; Mice; Peptide Fragments; Phenylephrine; Rats; Rats, Sprague-Dawley; Renin; Solitary Nucleus | 2008 |
Angiotensin II relaxations of bovine adrenal cortical arteries: role of angiotensin II metabolites and endothelial nitric oxide.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenal Cortex; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Arteries; Cattle; Endothelium, Vascular; Imidazoles; Losartan; Nitric Oxide; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2008 |
Angiotensin-converting enzyme inhibitors, inhibition of brain and peripheral angiotensin-converting enzymes, and left ventricular dysfunction in rats after myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Brain; Fibrosis; Hemodynamics; Indoles; Infusions, Intravenous; Injections, Subcutaneous; Kidney; Lisinopril; Male; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Renin-Angiotensin System; Sympathetic Nervous System; Ventricular Dysfunction, Left | 2008 |
Increased expression of angiotensin converting enzyme 2 in conjunction with reduction of neointima by angiotensin II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Aorta, Abdominal; Blood Pressure; Carotid Arteries; Catheterization; Disease Models, Animal; Heart Rate; Hyperplasia; Hypertension; Imidazoles; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Tunica Intima | 2008 |
Renin and prorenin disappearance in humans post-nephrectomy: evidence for binding?
Topics: Adenocarcinoma; Adult; Aged; Angiotensin I; Angiotensin II; Female; Humans; Kidney; Kidney Diseases; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Postoperative Period; Protein Binding; Pyelonephritis; Renal Dialysis; Renin; Renin-Angiotensin System | 2008 |
XIAP-associated factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.
Topics: Adaptor Proteins, Signal Transducing; Adenoviridae; Angiotensin I; Angiotensin II; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Cell Proliferation; Endothelium, Vascular; F-Box Proteins; Mice; Neovascularization, Physiologic; Proto-Oncogene Proteins c-myc; Receptor, TIE-1; Signal Transduction; Up-Regulation | 2008 |
Heme peroxidase-catalyzed iodination of human angiotensins and the effect of iodination on angiotensin converting enzyme activity.
Topics: Agaricales; Angiotensin I; Angiotensin II; Catalysis; Enzyme Inhibitors; Halogenation; Hemeproteins; Humans; Kinetics; Lactoperoxidase; Peptidyl-Dipeptidase A; Peroxidase | 2008 |
Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diabetes Mellitus, Experimental; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1 | 2008 |
The functional importance of the N-terminal region of human prolylcarboxypeptidase.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxypeptidases; Catalysis; Cell Line; Enzyme Stability; Humans; Peptide Fragments; Protein Conformation; Recombinant Proteins | 2008 |
Adapting the stretched sample method from tissue profiling to imaging.
Topics: Algorithms; Angiotensin I; Angiotensin II; Glass; Microspheres; Specimen Handling; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2008 |
The effect of recombinant aminopeptidase A on hypertension in spontaneously hypertensive rats: its effect in comparison with candesartan.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Baculoviridae; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Genetic Vectors; Glutamyl Aminopeptidase; Humans; Hypertension; Male; Mutation; Nitroprusside; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; Tetrazoles | 2008 |
MAP kinase/phosphatase pathway mediates the regulation of ACE2 by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cells, Cultured; Flavonoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Phosphatases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Okadaic Acid; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Vanadates | 2008 |
Expression of renin-angiotensin system and peroxisome proliferator-activated receptors in alcoholic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Biphenyl Compounds; Cardiomyopathy, Alcoholic; Disease Models, Animal; Flavonoids; Irbesartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptidyl-Dipeptidase A; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles; Ventricular Remodeling | 2008 |
Transgenic angiotensin-converting enzyme 2 overexpression in vessels of SHRSP rats reduces blood pressure and improves endothelial function.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Blood Pressure; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Hypertension; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Vasodilator Agents | 2008 |
Anti-plasmodium activity of angiotensin II and related synthetic peptides.
Topics: Aedes; Angiotensin I; Angiotensin II; Animals; Antiparasitic Agents; Cell Membrane; Chickens; Cytoplasm; Hemolysis; Humans; Malaria; Models, Statistical; Peptides; Plasmodium gallinaceum; Sporozoites | 2008 |
Angiotensin(1-7) blunts hypertensive cardiac remodeling by a direct effect on the heart.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Crosses, Genetic; Heart; Hypertension; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Ventricular Remodeling | 2008 |
Regulation of ACE2 in cardiac myocytes and fibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Atrial Natriuretic Factor; Butadienes; Cells, Cultured; Endothelin-1; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Heart Ventricles; Losartan; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Nitriles; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction | 2008 |
Ameliorative effect of Captopril and Valsartan on an animal model of diabetic cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cardiomyopathies; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Microscopy, Electron; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2008 |
Residues affecting the chloride regulation and substrate selectivity of the angiotensin-converting enzymes (ACE and ACE2) identified by site-directed mutagenesis.
Topics: Allosteric Site; Amino Acid Substitution; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Captopril; Catalysis; Catalytic Domain; Chlorides; Enzyme Inhibitors; Humans; Imidazoles; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Peptidyl-Dipeptidase A; Recombinant Proteins; Substrate Specificity | 2008 |
The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication?
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Female; Heart; Humans; Hypertension; Male; Mice; Mice, Knockout; Models, Animal; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2008 |
Angiotensin-(1-7) enhances angiotensin II induced phosphorylation of ERK1/2 in mouse bone marrow-derived dendritic cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Bone Marrow Cells; Dendritic Cells; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptors, Cell Surface; RNA, Messenger | 2009 |
Alterations in circulatory and renal angiotensin-converting enzyme and angiotensin-converting enzyme 2 in fetal programmed hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Betamethasone; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetal Development; Glucocorticoids; Hypertension; Kidney Tubules, Proximal; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Sheep | 2009 |
Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensins; Cross-Sectional Studies; Female; Hemodynamics; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Peptide Fragments; Portal Vein; Propranolol; Renin; Renin-Angiotensin System; Splanchnic Circulation | 2008 |
Angiotensin-converting enzyme-derived angiotensin II formation during angiotensin II-induced hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Kidney; Lisinopril; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A | 2009 |
Rehmannia glutinosa ameliorates the progressive renal failure induced by 5/6 nephrectomy.
Topics: Albumins; Angiotensin I; Angiotensin II; Animals; Blood Urea Nitrogen; Collagen Type IV; Creatinine; Kidney; Lipids; Male; Nephrectomy; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Rehmannia; Renal Insufficiency; RNA, Messenger; Transforming Growth Factor beta1 | 2009 |
Endogenous angiotensin-(1-7) reduces cardiac ischemia-induced dysfunction in diabetic hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; NF-kappa B; Nuclear Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA, Messenger; Signal Transduction | 2009 |
Therapeutic targets in liver transplantation: angiotensin II in nonsteatotic grafts and angiotensin-(1-7) in steatotic grafts.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Apoptosis; Fatty Liver; Graft Survival; Health; Liver Transplantation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Rats; Receptors, Angiotensin | 2009 |
Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Kidney; Male; Models, Animal; Myocardium; Nephrectomy; Peptide Fragments; Rats; Rats, Inbred WKY; Renin; Renin-Angiotensin System; RNA, Messenger | 2009 |
Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Dose-Response Relationship, Drug; Fluorometry; Genistein; Male; Rats; Rats, Wistar | 2009 |
Endogenous angiotensinergic system in neurons of rat and human trigeminal ganglia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Humans; Immunohistochemistry; In Situ Hybridization; Male; Neurons; Radioimmunoassay; Rats; Rats, Inbred WKY; RNA, Messenger; Trigeminal Ganglion | 2009 |
Tie-2 is overexpressed by monocytes in autoimmune thyroid disorders and participates in their recruitment to the thyroid gland.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Autoimmune Diseases; Cells, Cultured; Chemotaxis, Leukocyte; Female; Humans; Male; Middle Aged; Monocytes; Receptor, TIE-2; Thyroid Diseases; Thyroid Gland; Young Adult | 2009 |
Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.
Topics: Actins; Adult; Angiotensin I; Angiotensin II; Animals; Bile Ducts; Cells, Cultured; Drug Evaluation, Preclinical; Female; Hepatitis C, Chronic; Humans; Hydroxyproline; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Male; Middle Aged; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; RNA, Messenger; Up-Regulation | 2009 |
Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Common Bile Duct; Gene Expression Regulation, Enzymologic; Imidazoles; Leucine; Ligation; Lisinopril; Liver; Liver Cirrhosis, Experimental; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Portal Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Severity of Illness Index; Thiazepines; Time Factors; Vascular Resistance | 2009 |
[Effect of angiotensin1-7 on alpha-smooth muscle actin protein expression in rat hepatic stellate cells].
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Calcium; Cell Line; Gene Expression Regulation; Hepatic Stellate Cells; Peptide Fragments; Rats; rho-Associated Kinases; RNA, Messenger; Signal Transduction | 2009 |
NaCl plus chitosan as a dietary salt to prevent the development of hypertension in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood Urea Nitrogen; Body Weight; Chitosan; Chlorides; Creatinine; Heart; Histocytochemistry; Hypertension; Kidney; Male; Potassium; Potassium Chloride; Random Allocation; Rats; Rats, Inbred SHR; Sodium; Sodium Chloride, Dietary; Systole | 2009 |
Relationship between angiotensin-(1-7) and angiotensin II correlates with hemodynamic changes in human liver cirrhosis.
Topics: Angiotensin I; Angiotensin II; Animals; Cross-Sectional Studies; Female; Hemodynamics; Humans; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Splanchnic Circulation | 2009 |
Cell swelling, impulse conduction, and cardiac arrhythmias in the failing heart. Opposite effects of angiotensin II and angiotensin (1-7) on cell volume regulation.
Topics: Angiotensin I; Angiotensin II; Animals; Arrhythmias, Cardiac; Cardiomyopathies; Cell Size; Cells, Cultured; Cricetinae; Electrophysiology; Heart Conduction System; Heart Failure; Heart Ventricles; Hypotonic Solutions; Male; Membrane Potentials; Myocytes, Cardiac; Peptide Fragments; Pulse | 2009 |
Endothelium-dependent relaxation factor released by perivascular adipose tissue.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelium-Dependent Relaxing Factors; Immunohistochemistry; Male; Peptide Fragments; Potassium Channels; Pyridines; Rats; Rats, Wistar; Thiazepines | 2009 |
The uterine placental bed Renin-Angiotensin system in normal and preeclamptic pregnancy.
Topics: Alanine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Down-Regulation; Female; Gene Expression; Humans; Imidazoles; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Placenta; Pre-Eclampsia; Pregnancy; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stereoisomerism; Uterus | 2009 |
Acute modulation of myocardial function by angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Diastole; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Male; Myocardial Contraction; Naphthyridines; Nitroarginine; Papillary Muscles; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rabbits; Receptors, G-Protein-Coupled | 2009 |
Oxidized low-density lipoprotein, angiotensin II and increased waist cirumference are associated with valve inflammation in prehypertensive patients with aortic stenosis.
Topics: Adiponectin; Angiotensin I; Angiotensin II; Angiotensinogen; Aortic Valve Stenosis; Biomarkers; Blood Pressure; Humans; Interleukin-6; Linear Models; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Myocarditis; Oxidative Stress; Prehypertension; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Waist Circumference | 2010 |
Muscarinic effects and foetal cardiovascular and hormonal responses in utero.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Atropine; Biological Assay; Blood Pressure; Cardiovascular System; Female; Fetus; Heart Rate; Hormones; Infusions, Intravenous; Muscarinic Antagonists; Pregnancy; Sheep | 2009 |
Angiotensin-(1-7) antagonist, A-779, microinjection into the caudal ventrolateral medulla of renovascular hypertensive rats restores baroreflex bradycardia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradycardia; Heart Rate; Hypertension; Losartan; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats; Rats, Inbred F344 | 2009 |
Impairment of the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis contributes to the acceleration of two-kidney, one-clip Goldblatt hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Disease Progression; Hypertension, Renovascular; Infusion Pumps, Implantable; Peptide Fragments; Rats; Rats, Transgenic; Surgical Instruments; Telemetry; Vasodilator Agents | 2009 |
Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carbon Tetrachloride Poisoning; Extracellular Signal-Regulated MAP Kinases; Gene Deletion; Hepatic Stellate Cells; Ligation; Liver Cirrhosis; Mice; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Renin-Angiotensin System | 2009 |
Gonadotropin stimulation increases the expression of angiotensin-(1--7) and MAS receptor in the rat ovary.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Female; Gonadotropins, Equine; Immunohistochemistry; Injections, Subcutaneous; Neprilysin; Ovary; Peptide Fragments; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Prolyl Oligopeptidases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger; Serine Endopeptidases; Spectrometry, Fluorescence; Superovulation; Up-Regulation | 2009 |
Dietary sodium deprivation evokes activation of brain regional neurons and down-regulation of angiotensin II type 1 receptor and angiotensin-convertion enzyme mRNA expression.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Animals; Brain; Down-Regulation; Gene Expression Regulation; Hypothalamus; Hypothalamus, Anterior; Male; Neurons; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; RNA, Messenger; Sodium; Sodium, Dietary; Subfornical Organ | 2009 |
Mechanism of VEGF expression by high glucose in proximal tubule epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Enzyme Activation; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Glucose; Kidney Tubules, Proximal; Mice; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2010 |
Prenatal dehydration alters renin-angiotensin system associated with angiotensin-increased blood pressure in young offspring.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Baroreflex; Birth Weight; Blood Pressure; Female; Fetal Development; Gene Expression; Heart; Heart Rate; Hypertension; Liver; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Water Deprivation | 2009 |
A cysteine-type carboxypeptidase, cathepsin X, generates peptide receptor agonists.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Cathepsin K; Cell Line; Cloning, Molecular; Enzyme-Linked Immunosorbent Assay; Humans; Kallidin; Kallikrein-Kinin System; Peptidyl-Dipeptidase A; Radioligand Assay; Receptors, Peptide; Renin-Angiotensin System | 2010 |
Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction.
Topics: Adaptation, Physiological; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Disease Models, Animal; Enzyme Activation; Inflammation Mediators; Irbesartan; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardium; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Receptor, Angiotensin, Type 1; RNA, Messenger; Superoxides; Tetrazoles; Time Factors; Ultrasonography; Ventricular Remodeling | 2009 |
Major role for ACE-independent intrarenal ANG II formation in type II diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Arterioles; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Kidney; Male; Mice; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Serine Proteases; Signal Transduction; Vasoconstriction | 2010 |
Sensing of peptide hormones with dynamic combinatorial libraries of metal-dye complexes: the advantage of time-resolved measurements.
Topics: Angiotensin I; Angiotensin II; Coloring Agents; Combinatorial Chemistry Techniques; Discriminant Analysis; Kinetics; Metals; Peptide Hormones; Spectrophotometry, Ultraviolet; Time Factors; Titrimetry | 2009 |
Ontogenetic role of angiontensin-converting enzyme in rats: thirst and sodium appetite evaluation.
Topics: Adrenergic beta-Agonists; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Appetite; Blood Pressure; Body Weight; Captopril; Dehydration; Diuretics, Osmotic; Drinking; Female; Heart Rate; Injections, Intraventricular; Isoproterenol; Kidney; Lactation; Male; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Sodium Chloride; Sodium, Dietary; Thirst; Time Factors; Water-Electrolyte Balance | 2010 |
Angiotensin II up-regulates CX3CR1 expression in THP-1 monocytes: impact on vascular inflammation and atherogenesis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Endothelial Cells; Gene Expression Regulation; Humans; Inflammation; Jurkat Cells; Losartan; Monocytes; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Vasculitis; Vasoconstrictor Agents | 2010 |
A vaccine for hypertension based on peptide AngI-R: a pilot study.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Hypertension; Isoantibodies; Male; Pilot Projects; Rabbits; Random Allocation; Rats; Rats, Inbred SHR; Vaccines, Subunit | 2011 |
Decreased cardiac Ang-(1-7) is associated with salt-induced cardiac remodeling and dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Renin; RNA, Messenger; Sodium Chloride, Dietary; Ventricular Dysfunction, Left; Ventricular Remodeling | 2010 |
Angiotensin-(1-7)-angiotensin-converting enzyme 2 attenuates reactive oxygen species formation to angiotensin II within the cell nucleus.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Enzyme Inhibitors; Female; Imidazoles; Kidney Cortex; Leucine; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A; Pyridines; Reactive Oxygen Species; Receptors, Angiotensin; Sheep; Time Factors | 2010 |
Targeting the degradation of angiotensin II with recombinant angiotensin-converting enzyme 2: prevention of angiotensin II-dependent hypertension.
Topics: Anesthesia; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Dose-Response Relationship, Drug; Humans; Hypertension; Infusion Pumps; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins | 2010 |
Angiotensin-(1-7) prevents cardiomyocyte pathological remodeling through a nitric oxide/guanosine 3',5'-cyclic monophosphate-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Blood Pressure; Calcium; Cardiomegaly; Cell Size; Cells, Cultured; Cyclic GMP; Hypertension; Microscopy, Confocal; Myocytes, Cardiac; NFATC Transcription Factors; Nitric Oxide; Peptide Fragments; Protein Transport; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Signal Transduction | 2010 |
Infusion of angiotensin-(1-7) reduces glomerulosclerosis through counteracting angiotensin II in experimental glomerulonephritis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Proliferation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Gene Expression Regulation; Glomerulonephritis; Infusion Pumps, Implantable; Infusions, Subcutaneous; Isoantibodies; Kidney; Male; Mesangial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Plasminogen Activator Inhibitor 1; Proteinuria; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Time Factors; Transforming Growth Factor beta1 | 2010 |
Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Dietary Carbohydrates; Disease Models, Animal; Fructose; Hypertension; Hypertrophy, Left Ventricular; Insulin; Insulin Resistance; Male; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2010 |
Circulating rather than cardiac angiotensin-(1-7) stimulates cardioprotection after myocardial infarction.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Bone Marrow Cells; Heart Failure; Hemodynamics; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocytes, Cardiac; Peptide Fragments; Proto-Oncogene Proteins c-kit; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2010 |
Simultaneous determination of angiotensins II and 1-7 by capillary zone electrophoresis in plasma and urine from hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Hypertension; Limit of Detection; Linear Models; Male; Peptide Fragments; Rats; Rats, Wistar; Temperature | 2010 |
Development of a fast liquid chromatography/mass spectrometry screening method for angiotensin-converting enzyme (ACE) inhibitors in complex natural mixtures like snake venom.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bothrops; Chromatography, High Pressure Liquid; Complex Mixtures; Crotalid Venoms; Mass Spectrometry; Peptides; Peptidyl-Dipeptidase A; Reproducibility of Results | 2010 |
Angiotensin-(1-7) and angiotension II in the rostral ventrolateral medulla modulate the cardiac sympathetic afferent reflex and sympathetic activity in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Losartan; Male; Medulla Oblongata; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2010 |
Plasma and tissue levels of proangiotensin-12 and components of the renin-angiotensin system (RAS) following low- or high-salt feeding in rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Male; Radioimmunoassay; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Sodium Chloride | 2010 |
Angiotensin-(1-7) stimulates the phosphorylation of Akt in rat extracardiac tissues in vivo via receptor Mas.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Liver; Male; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction | 2010 |
Decoupling CE and ESI for a more robust interface with MS.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Electrolytes; Electrophoresis, Capillary; Equipment Design; Mass Spectrometry; Online Systems; Reproducibility of Results; Sensitivity and Specificity | 2010 |
Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Astrocytes; Biosensing Techniques; Blood Pressure; Calcium Signaling; Catecholamines; Disease Models, Animal; Genes, Reporter; Hypertension; Losartan; Medulla Oblongata; Membrane Potentials; Microscopy, Confocal; Patch-Clamp Techniques; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Tissue Culture Techniques | 2010 |
Improved lipid and glucose metabolism in transgenic rats with increased circulating angiotensin-(1-7).
Topics: Adipocytes; Adiponectin; Adipose Tissue; Adiposity; Angiotensin I; Angiotensin II; Animals; Biomarkers; Blood Glucose; Body Weight; Cells, Cultured; Cholesterol; Insulin; Leptin; Lipid Metabolism; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Time Factors; Triglycerides; Up-Regulation | 2010 |
Inhibition of angiotensin-converting enzyme 2 exacerbates cardiac hypertrophy and fibrosis in Ren-2 hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cardiomegaly; Fibrosis; Heart Ventricles; Imidazoles; Leucine; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Transgenic | 2010 |
Regulation of angiotensin converting enzyme II by angiotensin peptides in human cardiofibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Fibroblasts; Humans; Mitogen-Activated Protein Kinase 3; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Up-Regulation | 2010 |
Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Chronic Disease; Disease Models, Animal; Glomerular Filtration Rate; Hematocrit; Imidazoles; Infusion Pumps; Injections, Subcutaneous; Inulin; Kidney; Kidney Diseases; Leucine; Losartan; Male; Mice; Nephrectomy; Organ Size; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Time Factors | 2010 |
Chronic treatment with quercetin does not inhibit angiotensin-converting enzyme in vivo or in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Captopril; Chromatography, High Pressure Liquid; In Vitro Techniques; Injections, Intraperitoneal; Male; Peptidyl-Dipeptidase A; Quercetin; Rats; Rats, Wistar | 2010 |
Reduced expression of angiotensin I-converting enzyme in caveolin-1 knockout mouse lungs.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Capillaries; Caveolin 1; Endothelial Cells; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Immunohistochemistry; Lung; Mice; Mice, Knockout; Peptidyl-Dipeptidase A; Perfusion; Pulmonary Artery; Signal Transduction | 2010 |
Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Superoxides; Time Factors; Vasodilation; Vasodilator Agents | 2010 |
Long-term effects of telmisartan on blood pressure, the renin-angiotensin-aldosterone system, and lipids in hypertensive patients.
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Natriuretic Factor; Benzimidazoles; Benzoates; Biomarkers; Blood Pressure; Cholesterol; Drug Administration Schedule; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Peptidyl-Dipeptidase A; Prospective Studies; Renin; Renin-Angiotensin System; Telmisartan; Time Factors; Treatment Outcome; Triglycerides | 2010 |
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Kidney; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury; Urine | 2010 |
Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cadherins; Cell Differentiation; Cell Line; Epithelial Cells; Imidazoles; Kidney Tubules; Mesoderm; Models, Animal; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Angiotensin-(1-7) attenuates hyposmolarity-induced ANP secretion via the Na+-K+ pump.
Topics: Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Osmolar Concentration; Peptide Fragments; Perfusion; Rats; Rats, Sprague-Dawley; Sodium-Potassium-Exchanging ATPase; Stress, Physiological; Time Factors | 2010 |
Angiotensin-converting enzyme 2 autoantibodies: further evidence for a role of the renin-angiotensin system in inflammation.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autoantibodies; Humans; Hypertension; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Scleroderma, Systemic | 2010 |
Renin-angiotensin system may trigger kidney damage in NOD mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blotting, Western; Bradykinin; Kidney; Mice; Mice, Inbred NOD; Organ Specificity; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2011 |
Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cerebral Arterial Diseases; Cerebral Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitroprusside; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Superoxides; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Genetically determined angiotensin converting enzyme level and myocardial tolerance to ischemia.
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Apoptosis; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Fumarates; Heart; Kinins; Lung; Mice; Mice, Mutant Strains; Myocardial Infarction; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Renin; Reperfusion Injury | 2010 |
Angiotensin-(1-7), its receptor Mas, and the angiotensin-converting enzyme type 2 are expressed in the human ovary.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Autoradiography; Female; Fertilization in Vitro; Follicular Fluid; Humans; Immunohistochemistry; Iodine Radioisotopes; Middle Aged; Ovary; Ovulation Induction; Peptide Fragments; Peptidyl-Dipeptidase A; Postmenopause; Premenopause; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Tetrazoles | 2010 |
Angiotensin (1-7) receptor antagonism equalizes angiotensin II-induced hypertension in male and female spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Female; Hypertension; Kidney Cortex; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sex Factors; Vasoconstrictor Agents | 2010 |
Drinking and arterial blood pressure responses to ANG II in young and old rats.
Topics: Adaptation, Physiological; Age Factors; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Baroreflex; Behavior, Animal; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Heart Rate; Infusions, Intravenous; Male; Minoxidil; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Urodynamics; Vasodilator Agents; Water-Electrolyte Balance | 2010 |
The renin-angiotensin system and hypertension in autosomal recessive polycystic kidney disease.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Hypertension; Kidney; Male; Mutation; Peptidyl-Dipeptidase A; Polycystic Kidney, Autosomal Recessive; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Time Factors | 2010 |
Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Movement; Cell Proliferation; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Peptide Fragments; Phosphorylation; Receptor, Angiotensin, Type 1 | 2010 |
Studies on the mechanism of antihypertensive action by nicotianamine.
Topics: Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Azetidinecarboxylic Acid; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Plant Extracts; Potassium Chloride; Rats; Rats, Wistar; Vasoconstriction | 2010 |
Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain.
Topics: Angiotensin I; Angiotensin II; Animals; Brain; Radioligand Assay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2010 |
[Angiotensin I, angiotensin II, angiotensin III].
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Humans; Radioimmunoassay | 2010 |
Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Line; Gene Expression Regulation; Membrane Potentials; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Peptide Fragments; Potassium; Protein Isoforms; Receptors, Angiotensin; Signal Transduction | 2011 |
Angiotensin II and angiotensin-(1-7) decrease sFlt1 release in normal but not preeclamptic chorionic villi: an in vitro study.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensins; Cells, Cultured; Chorionic Villi; Down-Regulation; Female; Humans; Middle Aged; Peptide Fragments; Placenta; Placental Circulation; Placental Lactogen; Pre-Eclampsia; Pregnancy; Protein Isoforms; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Young Adult | 2010 |
Knockout of angiotensin 1-7 receptor Mas worsens the course of two-kidney, one-clip Goldblatt hypertension: roles of nitric oxide deficiency and enhanced vascular responsiveness to angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Progression; Hypertension, Renovascular; Male; Mice; Mice, Knockout; Nitric Oxide; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Surgical Instruments; Vasomotor System | 2010 |
Intrarenal angiotensin-converting enzyme induces hypertension in response to angiotensin I infusion.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Female; Hypertension; Infusions, Subcutaneous; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2011 |
Angiotensin1-9 antagonises pro-hypertrophic signalling in cardiomyocytes via the angiotensin type 2 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Cell Line, Transformed; Cell Survival; Cells, Cultured; HeLa Cells; Humans; Hypertrophy; Myocytes, Cardiac; Peptide Fragments; Rabbits; Rats; Receptor, Angiotensin, Type 2; Signal Transduction | 2011 |
Enhanced angiotensin-converting enzyme 2 attenuates angiotensin II-induced collagen production via AT1 receptor-phosphoinositide 3-kinase-Akt pathway.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Kidney Failure, Chronic; Mesangial Cells; Mice; Molecular Targeted Therapy; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Transcriptional Activation | 2011 |
Reciprocal changes in renal ACE/ANG II and ACE2/ANG 1-7 are associated with enhanced collecting duct renin in Goldblatt hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension, Renovascular; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Renin; RNA, Messenger | 2011 |
Angiotensinogen metabolism in rat aorta: robust formation of proangiotensin-12.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Angiotensins; Animals; Aorta; Male; Peptide Fragments; Rats; Rats, Wistar; Renin; Renin-Angiotensin System | 2010 |
Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Atherosclerosis; Bone Marrow Cells; Bone Marrow Transplantation; Cell Adhesion; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Cytokines; Dietary Fats; Disease Models, Animal; Endothelial Cells; Humans; Inflammation Mediators; Losartan; Macrophages; Male; Mice; Mice, Knockout; Monocytes; Peptide Fragments; Peptidyl-Dipeptidase A; Receptors, LDL | 2011 |
Enhanced susceptibility to biomechanical stress in ACE2 null mice is prevented by loss of the p47(phox) NADPH oxidase subunit.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomyopathy, Dilated; Disease Models, Animal; Enzyme Activation; Extracellular Matrix; Heart Failure; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Stress, Mechanical; Superoxides; Time Factors; Ventricular Function, Left; Ventricular Remodeling | 2011 |
Visfatin stimulates a cellular renin-angiotensin system in cultured rat mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cell Line; Diabetic Nephropathies; Glomerular Mesangium; Nicotinamide Phosphoribosyltransferase; Peptidyl-Dipeptidase A; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger | 2011 |
Angiotensin-(1-7) blockade attenuates captopril- or hydralazine-induced cardiovascular protection in spontaneously hypertensive rats treated with NG-nitro-L-arginine methyl ester.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Brain; Captopril; Cytokines; Heart; Hydralazine; Hypertension; In Vitro Techniques; Insulin; Kidney; Leptin; Male; Myocardial Contraction; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Proteinuria; Rats; Rats, Inbred SHR; Ventricular Function, Left | 2011 |
Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carotid Sinus; Collagen; Denervation; Disease Models, Animal; Heart Ventricles; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Peptide Fragments; Random Allocation; Rats; Rats, Wistar; Renin-Angiotensin System | 2010 |
Impairment of the Plasmodium falciparum erythrocytic cycle induced by angiotensin peptides.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Erythrocytes; Humans; Life Cycle Stages; Malaria, Falciparum; Peptide Fragments; Peptides; Plasmodium falciparum; Rats; Renin-Angiotensin System; Schizonts | 2011 |
Attenuating effect of angiotensin-(1-7) on angiotensin II-mediated NAD(P)H oxidase activation in type 2 diabetic nephropathy of KK-A(y)/Ta mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Body Weight; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Immunohistochemistry; Mesangial Cells; Mice; NADPH Oxidases; Peptide Fragments; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Statistics, Nonparametric | 2011 |
Chronic treatment with angiotensin-(1-7) improves renal endothelial dysfunction in apolipoproteinE-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apolipoproteins E; Atherosclerosis; Cyclic GMP; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydrogen Peroxide; Infusion Pumps, Implantable; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation | 2011 |
Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats.
Topics: Achillea; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Flavonoids; Hypertension; Male; Methylene Chloride; Oils, Volatile; Peptidyl-Dipeptidase A; Phytotherapy; Plant Extracts; Rats; Rats, Wistar | 2011 |
Purification and characterization of angiotensin converting enzyme 2 (ACE2) from murine model of mesangial cell in culture.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Cells, Cultured; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Kinetics; Mesangial Cells; Mice; Microscopy, Fluorescence; Peptide Fragments; Peptidyl-Dipeptidase A; Sequence Analysis, DNA | 2011 |
Carboxypeptidase activity common to viridans group streptococci cleaves angiotensin I to angiotensin II: an activity homologous to angiotensin-converting enzyme (ACE).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Base Sequence; Captopril; Carboxypeptidases; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enalapril; Endocarditis, Bacterial; Fibrinogen; Humans; Lisinopril; Molecular Sequence Data; Peptidyl-Dipeptidase A; Sequence Analysis, DNA; Streptococcal Infections; Streptococcus gordonii | 2011 |
Beneficial effects of angiotensin (1-7) in diabetic rats with cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dyslipidemias; Fibrosis; Heart Ventricles; Hypertrophy, Left Ventricular; Lipids; Nitrates; Nitrites; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2011 |
Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Carotid Arteries; Disease Models, Animal; Enalapril; Hypertension; Immunohistochemistry; Male; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Serine Endopeptidases; Time Factors; Up-Regulation; Vasoconstriction | 2011 |
Evidence of an intracellular angiotensin-generating system and non-AT1, non-AT2 binding site in a human pancreatic cell line.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Binding Sites; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Humans; Intracellular Space; Losartan; Pancreatic Neoplasms; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Endothelial Growth Factor A | 2011 |
Contributions of ACE and mast cell chymase to endogenous angiotensin II generation and leucocyte recruitment in vivo.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Movement; Chymases; Leukocytes; Male; Mast Cells; Mice; Mice, Inbred C57BL; p-Methoxy-N-methylphenethylamine; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1 | 2011 |
Angiotensin-(1-7) induces ovulation and steroidogenesis in perfused rabbit ovaries.
Topics: Angiotensin I; Angiotensin II; Animals; Chorionic Gonadotropin; Estradiol; Female; Gonadotropins, Equine; Oocytes; Ovarian Follicle; Ovary; Ovulation; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Receptors, G-Protein-Coupled | 2011 |
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Endothelin-1; Enzyme Activation; Infarction, Middle Cerebral Artery; Male; Nitric Oxide Synthase Type II; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke | 2011 |
Role of angiotensin-(1-7) in rostral ventrolateral medulla in blood pressure regulation via sympathetic nerve activity in Wistar-Kyoto and spontaneous hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan | 2011 |
Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cystinyl Aminopeptidase; Dietary Fats; Dietary Sucrose; Drug Administration Schedule; Glucose Intolerance; Hyperglycemia; Indomethacin; Insulin; Insulin Receptor Substrate Proteins; Janus Kinase 2; Losartan; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction | 2011 |
Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Body Weight; Diabetes Mellitus; ErbB Receptors; Glucose; Hyperglycemia; Male; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinazolines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases; Transcriptional Activation; Tyrphostins | 2012 |
Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Chronic Disease; Consciousness; Disease Models, Animal; Heart Failure; Heart Rate; Infusions, Intraventricular; Kidney; Male; Metoprolol; Peptide Fragments; Rabbits; Sympathetic Nervous System; Vagus Nerve | 2011 |
[Influence of angiotensin-(1-7) on angiotensin II induced rat's tubular epithelial-myofibroblast transdifferentiation].
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cadherins; Cell Line; Cell Transdifferentiation; Epithelial Cells; Fibronectins; Gene Expression Regulation; Kidney Tubules; Matrix Metalloproteinase 2; Myofibroblasts; Peptide Fragments; Rats; RNA, Messenger | 2011 |
Direct renin inhibition in a rat model of chronic allograft injury.
Topics: Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Fumarates; Kidney; Kidney Transplantation; Male; Models, Animal; Peptide Fragments; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles; Transplantation, Homologous | 2011 |
Niaspan enhances vascular remodeling after stroke in type 1 diabetic rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Blood-Brain Barrier; Cerebral Hemorrhage; Cerebrovascular Circulation; Cholesterol, HDL; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Disease Models, Animal; Infarction, Middle Cerebral Artery; Male; Niacin; Rats; Rats, Wistar; Vasodilator Agents | 2011 |
Renin released from mast cells activated by circulating MCP-1 initiates the microvascular phase of the systemic inflammation of alveolar hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Cell Degranulation; Cells, Cultured; Chemokine CCL2; Hypoxia; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages, Peritoneal; Peptidyl-Dipeptidase A; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Receptors, CCR2; Renin; Renin-Angiotensin System | 2011 |
Plasma and tissue concentrations of proangiotensin-12 in rats treated with inhibitors of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Blood Pressure; Body Weight; Imidazolidines; Kidney; Losartan; Male; Myocardium; Organ Size; Peptide Fragments; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Renin-Angiotensin System | 2012 |
Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Enzyme Induction; Heart Failure; Humans; Male; Medulla Oblongata; Mice; Mice, Knockout; Myocardial Ischemia; Nerve Tissue Proteins; Nitric Oxide; Norepinephrine; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Reflex, Abnormal; Sympathetic Nervous System | 2011 |
The arterial depressor response to chronic low-dose angiotensin II infusion in female rats is estrogen dependent.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Infusions, Subcutaneous; Kidney; Models, Animal; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Signal Transduction; Vasoconstrictor Agents | 2012 |
Characterization and significance of ACE2 and Mas receptor in human colon adenocarcinoma.
Topics: Adenocarcinoma; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Caco-2 Cells; Cell Cycle; Colonic Neoplasms; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Intestinal Mucosa; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2012 |
Decidualized pseudopregnant rat uterus shows marked reduction in Ang II and Ang-(1-7) levels.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blastocyst; Cell Polarity; Decidua; Down-Regulation; Embryo Implantation; Female; Isoenzymes; Models, Biological; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Transport; Pseudopregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Uterus | 2012 |
Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autoimmune Diseases; Benzimidazoles; Biphenyl Compounds; Blotting, Western; Cell Survival; Endoplasmic Reticulum Stress; Heart Diseases; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocarditis; Myosins; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Receptors, G-Protein-Coupled; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Tetrazoles | 2012 |
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac remodeling associated with upregulation of dual-specificity phosphatase 1.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Cardiomegaly; Drug Interactions; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Myocardium; Peptide Fragments; Rats; Rats, Sprague-Dawley; Up-Regulation; Vasoconstrictor Agents; Ventricular Remodeling | 2012 |
Angiotensin-(1-7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; MAP Kinase Signaling System; Mesangial Cells; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley | 2012 |
Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Heart Rate; Hypothalamus; Male; Morpholines; Neurons; Peptide Fragments; PTEN Phosphohydrolase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vanadium Compounds | 2012 |
Role of renin-angiotensin system and oxidative status on the maternal cardiovascular regulation in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Female; Hypertension; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Inbred SHR; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2012 |
Angiotensin-converting enzyme 2 regulates renal atrial natriuretic peptide through angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Atrial Natriuretic Factor; Diabetes Mellitus; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System | 2012 |
Angiotensin-(1-7) inhibits vascular remodelling in rat jugular vein grafts via reduced ERK1/2 and p38 MAPK activity.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Blood Vessel Prosthesis; Body Weight; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Hemodynamics; Infusions, Intravenous; Jugular Veins; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Transplantation, Autologous | 2011 |
Angiotensin-(1-7) abrogates mitogen-stimulated proliferation of cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Collagen; Cyclooxygenase 2; DNA; Dual Specificity Phosphatase 1; Endothelin-1; Fibroblasts; Fibrosis; Gene Expression Regulation; Heart Diseases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Peptide Fragments; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Rats; Signal Transduction | 2012 |
Angiotensin-(1-7) inhibits allergic inflammation, via the MAS1 receptor, through suppression of ERK1/2- and NF-κB-dependent pathways.
Topics: Allergens; Angiotensin I; Angiotensin II; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cells, Cultured; Humans; Leukocytes, Mononuclear; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Ovalbumin; Peptide Fragments; Phytohemagglutinins; Pneumonia; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2012 |
Differential regulation of circulating and renal ACE2 and ACE in hypertensive mRen2.Lewis rats with early-onset diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Blood Pressure; Blotting, Western; C-Reactive Protein; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; Female; Hypertension; Immunohistochemistry; Kidney; Male; Muscle Contraction; Muscle, Smooth, Vascular; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin; Renin-Angiotensin System; Sex Characteristics; Vascular Endothelial Growth Factor A | 2012 |
Duplexed iMALDI for the detection of angiotensin I and angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Antibodies; Calibration; Enzyme Activation; Enzyme Assays; Humans; Immunoglobulin G; Isotope Labeling; Limit of Detection; Plasma; Reference Values; Renin; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry | 2012 |
Granulocyte colony stimulating factor prevents kidney infarction and attenuates renovascular hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Granulocyte Colony-Stimulating Factor; Hemodynamics; Hypertension, Renovascular; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL | 2012 |
Angiotensin-(1-7) suppresses the number and function of the circulating fibrocytes by upregulating endothelial nitric oxide synthase expression.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blood Cells; Cell Proliferation; Cells, Cultured; Collagen Type I; Fibroblasts; Humans; Hydroxyproline; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Up-Regulation | 2012 |
Angiotensin converting enzyme 2 contributes to sex differences in the development of obesity hypertension in C57BL/6 mice.
Topics: 3T3-L1 Cells; Adipocytes; Adiposity; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diet, High-Fat; Disease Models, Animal; Estrogens; Female; Gene Expression Regulation, Enzymologic; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Risk Factors; RNA, Messenger; Sex Factors; Testosterone; Time Factors; Weight Gain | 2012 |
Enzymatic processing of angiotensin peptides by human glomerular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Carboxypeptidases; Cells, Cultured; Endothelial Cells; Humans; Kidney Glomerulus; Neprilysin; Peptidyl-Dipeptidase A; Podocytes; Renin-Angiotensin System | 2012 |
Divergent pathways for the angiotensin-(1-12) metabolism in the rat circulation and kidney.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Angiotensins; Animals; Hypertension; Kidney; Lisinopril; Male; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred Lew; Renin | 2012 |
Modeling of angiotensin II-angiotensin-(1-7) counterbalance in disease progression in spontaneously hypertensive rats treated with/without perindopril.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Models, Biological; Peptide Fragments; Perindopril; Rats; Rats, Inbred SHR | 2012 |
Structure and reorientational dynamics of angiotensin I and II: a microscopic physical insight.
Topics: Angiotensin I; Angiotensin II; Circular Dichroism; Fluorescence Polarization; Molecular Dynamics Simulation; Peptides; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Water | 2012 |
Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chymases; Colonic Neoplasms; Diabetes Complications; Diabetes Mellitus; Glucose; Glycated Hemoglobin; HT29 Cells; Humans; Hyperglycemia; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Oligoribonucleotides, Antisense; Receptor, Angiotensin, Type 1; Renin; RNA Interference; RNA, Small Interfering | 2012 |
Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Interactions; Endothelin-1; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Glomerular Mesangium; Imidazoles; Losartan; MAP Kinase Signaling System; Mesangial Cells; Microscopy, Confocal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transforming Growth Factor beta1 | 2012 |
The Mas receptor mediates modulation of insulin signaling by angiotensin-(1-7).
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dyslipidemias; Fructose; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; GTPase-Activating Proteins; Hypertension; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction | 2012 |
Unraveling the glomerular RAS: one peptidase at a time.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Endothelial Cells; Humans; Kidney Glomerulus; Peptide Hydrolases; Peptidyl-Dipeptidase A; Podocytes; Renin-Angiotensin System | 2012 |
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury | 2012 |
Role of angiotensin-converting enzyme (ACE and ACE2) imbalance on tourniquet-induced remote kidney injury in a mouse hindlimb ischemia-reperfusion model.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Urea Nitrogen; Creatinine; Hindlimb; Kidney; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Multiple Organ Failure; Oxidative Stress; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Reperfusion Injury; Superoxide Dismutase; Tourniquets | 2012 |
High Na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese Zucker rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Hypertension, Renal; Kidney; Kidney Cortex; Male; Mass Spectrometry; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Sodium, Dietary; Spectrometry, Mass, Electrospray Ionization | 2012 |
Regulation of the renin-angiotensin system (RAS) in BeWo and HTR-8/SVneo trophoblast cell lines.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cell Line, Transformed; Cell Line, Tumor; Choriocarcinoma; Cyclic AMP; Gene Expression Regulation; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Precursors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Secretory Pathway; Signal Transduction; Trophoblasts | 2012 |
Rosiglitazone inhibits angiotensin II-induced C-reactive protein production in human aortic endothelial cells through regulating AT(1)-ROS-MAPK signal pathway.
Topics: Angiotensin I; Angiotensin II; Anti-Inflammatory Agents; Aorta; C-Reactive Protein; Cells, Cultured; Endothelial Cells; Humans; Mitogen-Activated Protein Kinases; PPAR gamma; Reactive Oxygen Species; RNA, Messenger; Rosiglitazone; Thiazolidinediones | 2012 |
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Collagen Type I; Collagen Type III; Desoxycorticosterone; Disease Models, Animal; Heart Rate; Heart Ventricles; Hypertension; Infusions, Intraventricular; Kidney; Lateral Ventricles; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sympathetic Nervous System; Time Factors | 2012 |
Intrarenal angiotensin III is the predominant agonist for proximal tubule angiotensin type 2 receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Benzimidazoles; Biphenyl Compounds; Female; Imidazoles; Kidney Tubules, Proximal; Models, Animal; Natriuresis; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Tetrazoles | 2012 |
Central ventilatory and cardiovascular actions of angiotensin peptides in trout.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Female; Gills; Heart Rate; Injections, Intraventricular; Male; Peptide Fragments; Time Factors; Trout | 2012 |
[Role of rennin-angiotensin system in cholinergic agonist carbachol-induced cardiovascular responses in ovine fetus].
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Fetus; Heart Rate; Renin-Angiotensin System; Sheep; Vasopressins | 2012 |
Angiotensin II-induced mitochondrial Nox4 is a major endogenous source of oxidative stress in kidney tubular cells.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Apoptosis Inducing Factor; Cell Survival; Cells, Cultured; Cytochromes c; Gene Expression Regulation; Hydrogen Peroxide; Kidney Tubules; Membrane Potential, Mitochondrial; Mitochondria; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Rats; Signal Transduction; Superoxides | 2012 |
Suppressing inflammation by inhibiting the NF-κB pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Anti-Inflammatory Agents; Behavior, Animal; Cerebrovascular Circulation; Imidazoles; Infarction, Middle Cerebral Artery; Inflammation; Male; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2012 |
Inhibition of angiotensin II-induced contraction of human airway smooth muscle cells by angiotensin-(1-7) via downregulation of the RhoA/ROCK2 signaling pathway.
Topics: Actins; Angiotensin I; Angiotensin II; Bronchi; Cells, Cultured; Humans; Muscle Contraction; Myocytes, Smooth Muscle; Peptide Fragments; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction | 2012 |
Involvement of brain ANG II in acute sodium depletion induced salty taste changes.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Appetite; Appetitive Behavior; Body Weight; Captopril; Drug Combinations; Drug Evaluation, Preclinical; Furosemide; Immunohistochemistry; Male; Paraventricular Hypothalamic Nucleus; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Sodium Chloride, Dietary; Subfornical Organ; Supraoptic Nucleus; Taste | 2012 |
Targeted analyte detection by standard addition improves detection limits in matrix-assisted laser desorption/ionization mass spectrometry.
Topics: Amyloid beta-Peptides; Angiotensin I; Angiotensin II; Limit of Detection; Peptide Fragments; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Differences in oxidative stress status and expression of MKP-1 in dorsal medulla of transgenic rats with altered brain renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Blood Pressure; Disease Models, Animal; Dual Specificity Phosphatase 1; Gene Expression Regulation; Hypertension; Ion Channels; JNK Mitogen-Activated Protein Kinases; Male; Medulla Oblongata; Mitochondria; Mitochondrial Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NADPH Oxidases; Oligonucleotides, Antisense; Oxidative Stress; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Signal Transduction; Uncoupling Protein 2 | 2012 |
Exercise induces renin-angiotensin system unbalance and high collagen expression in the heart of Mas-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Collagen; Collagen Type I; Collagen Type III; Gene Expression Regulation; Heart; Hypertrophy, Left Ventricular; Male; Mice; Mice, Knockout; Peptide Fragments; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Remodeling | 2012 |
Perinatal Na+ overload programs raised renal proximal Na+ transport and enalapril-sensitive alterations of Ang II signaling pathways during adulthood.
Topics: Adenosine Triphosphatases; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blood Pressure; Body Weight; Cation Transport Proteins; Creatinine; Cyclic AMP-Dependent Protein Kinases; Enalapril; Female; Gene Expression Regulation; Kidney Tubules, Proximal; Lipid Peroxidation; Macrophages; Male; Parturition; Pregnancy; Protein Kinase C; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Transduction; Sodium; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances; Water; Weaning | 2012 |
Loss of ACE2 exaggerates high-calorie diet-induced insulin resistance by reduction of GLUT4 in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diet, High-Fat; Dietary Carbohydrates; Energy Intake; Glucose; Glucose Intolerance; Glucose Transporter Type 4; Homeostasis; Insulin Resistance; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Myoblasts; Myogenic Regulatory Factors; Peptide Fragments; Peptidyl-Dipeptidase A | 2013 |
Captopril avoids hypertension, the increase in plasma angiotensin II but increases angiotensin 1-7 and angiotensin II-induced perfusion pressure in isolated kidney in SHR.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Hypertension; Kidney; Kidney Cortex; Kidney Medulla; Male; Peptide Fragments; Prehypertension; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Specific Pathogen-Free Organisms; Vascular Resistance | 2012 |
Angiogenic factors and their soluble receptors predict organ dysfunction and mortality in post-cardiac arrest syndrome.
Topics: Aged; Angiotensin I; Angiotensin II; Female; Heart Arrest; Humans; Male; Middle Aged; Mortality; Multiple Organ Failure; Predictive Value of Tests; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Syndrome; Vascular Endothelial Growth Factor A | 2012 |
Angiotensin-(1-7) treatment ameliorates angiotensin II-induced apoptosis of human umbilical vein endothelial cells.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blotting, Western; Caspase 3; Cell Culture Techniques; Dose-Response Relationship, Drug; Endothelial Cells; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Humans; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Scavenger Receptors, Class E; Up-Regulation | 2012 |
[Angiotensin (1-7) inhibits angiotensin II-stimulated expression of connective tissue growth factor mRNA in hepatic stellate cells].
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Connective Tissue Growth Factor; Hepatic Stellate Cells; Humans; Peptide Fragments; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction | 2012 |
Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blotting, Western; Endothelium, Vascular; In Situ Hybridization; Liver; Liver Circulation; Liver Cirrhosis; Male; Methoxamine; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Vasoconstrictor Agents | 2013 |
Angiotensin-(1-7) modulates renin-angiotensin system associated with reducing oxidative stress and attenuating neuronal apoptosis in the brain of hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Hypertension; Male; Malondialdehyde; Neurons; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Superoxide Dismutase | 2013 |
Angiotensin-(1-7) in paraventricular nucleus modulates sympathetic activity and cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Adenine; Afferent Pathways; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Body Weight; Bucladesine; Cyclic AMP; Heart; Hypertension, Renovascular; Kidney; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Reflex; Sympathetic Nervous System; Thionucleotides | 2012 |
An integrated physiology-based model for the interaction of RAA system biomarkers with drugs.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Computer Simulation; Enalapril; Enalaprilat; Humans; Injections, Intravenous; Models, Biological; Renin-Angiotensin System | 2012 |
Association of all-trans retinoic acid treatment with the renin-angiotensin aldosterone system expression in glomerulosclerosis rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen Type IV; Fibronectins; Glomerulonephritis; Immunohistochemistry; Kidney Glomerulus; Male; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; RNA, Messenger; Tretinoin | 2013 |
Impact of ACE2 deficiency and oxidative stress on cerebrovascular function with aging.
Topics: Acetylcholine; Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Male; Mice; Mice, Knockout; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Vasculitis; Vasodilation; Vasodilator Agents | 2012 |
Interaction between TGF-β and ACE2-Ang-(1-7)-Mas pathway in high glucose-cultured NRK-52E cells.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Benzamides; Cells, Cultured; Chromones; Dioxoles; Fibronectins; Gene Expression Regulation; Glucose; Janus Kinase 2; LLC-PK1 Cells; Molecular Sequence Data; Morpholines; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, G-Protein-Coupled; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Swine; Transcription, Genetic; Transforming Growth Factor beta; Tyrphostins | 2013 |
Angiotensin-(1-7) regulates Angiotensin II-induced VCAM-1 expression on vascular endothelial cells.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; Cell Line; Endothelium, Vascular; Humans; NF-kappa B; Peptide Fragments; Protein Transport; Receptors, G-Protein-Coupled; Vascular Cell Adhesion Molecule-1 | 2013 |
Angiotensin (1-7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Adhesion; Chemokine CCL2; DNA; Endothelial Cells; Female; Humans; Inflammation; Male; NF-kappa B; Peptide Fragments; Rabbits; Scavenger Receptors, Class E; Vascular Cell Adhesion Molecule-1 | 2013 |
Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats.
Topics: Afferent Pathways; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Heart; Heart Rate; Hypertension, Renovascular; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Reflex; Sympathetic Nervous System; Systole | 2012 |
Angiotensin-(1-7) inhibits vascular calcification in rats.
Topics: Actins; Alkaline Phosphatase; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Calcium-Binding Proteins; Calponins; Cholecalciferol; Cytoskeletal Proteins; Disease Models, Animal; Gene Expression Regulation; Male; Microfilament Proteins; Muscle Proteins; Muscle, Smooth, Vascular; Nicotine; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Vascular Calcification | 2013 |
Gynura procumbens causes vasodilation by inhibiting angiotensin II and enhancing bradykinin actions.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Arterial Pressure; Asteraceae; Blood Pressure; Bradykinin; Cardiovascular Agents; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Plant Extracts; Rats; Rats, Sprague-Dawley; Vasodilation; Vasodilator Agents | 2013 |
Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation.
Topics: Angiotensin I; Angiotensin II; Animals; Bleeding Time; Blood Platelets; Bone Marrow Transplantation; Cyclic AMP; Cyclic GMP; Epoprostenol; Immunoblotting; Mice; Mice, 129 Strain; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Thrombosis; Time Factors | 2013 |
Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Carboxypeptidases; Dipeptides; Imidazoles; Kidney; Leucine; Male; Mice; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2013 |
Diet composition modulates expression of sirtuins and renin-angiotensin system components in adipose tissue.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cholesterol, HDL; Diet, High-Fat; Dietary Fats; Dietary Proteins; Dietary Sucrose; Glucose; Lipids; Male; Mice; Mice, Inbred Strains; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Renin; Renin-Angiotensin System; Sirtuins; Triglycerides | 2013 |
Up-regulation of components of the renin-angiotensin system in liver fibrosis in the rat induced by CCL₄.
Topics: Angiotensin I; Angiotensin II; Animals; Blotting, Western; Carbon Tetrachloride; Gene Expression Regulation, Enzymologic; Liver Cirrhosis; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Renin-Angiotensin System; RNA; Statistics, Nonparametric; Up-Regulation | 2013 |
The balance between human maternal plasma angiotensin II and angiotensin 1-7 levels in early gestation pregnancy is influenced by fetal sex.
Topics: Angiotensin I; Angiotensin II; C-Reactive Protein; Female; Fetus; Humans; Male; Maternal Welfare; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Renin-Angiotensin System; Sex Characteristics | 2014 |
Discovery and characterization of alamandine: a novel component of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Drug Discovery; Humans; Male; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2013 |
Predominance of AT(1) blockade over mas-mediated angiotensin-(1-7) mechanisms in the regulation of blood pressure and renin-angiotensin system in mRen2.Lewis rats.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Imidazoles; Male; Olmesartan Medoxomil; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred Lew; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Tetrazoles | 2013 |
Complete blockade of the vasorelaxant effects of angiotensin-(1-7) and bradykinin in murine microvessels by antagonists of the receptor Mas.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Human Umbilical Vein Endothelial Cells; Humans; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Microvessels; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasodilation; Vasodilator Agents | 2013 |
Angiotensin-(1-7) inhibits autophagy in the brain of spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Autophagy; Blood Pressure; Brain; Hypertension; Imidazoles; Male; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2013 |
The effects of para-chloromercuribenzoic acid and different oxidative and sulfhydryl agents on a novel, non-AT1, non-AT2 angiotensin binding site identified as neurolysin.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Binding Sites; Losartan; Male; Metalloendopeptidases; Oxidation-Reduction; p-Chloromercuribenzoic Acid; Rats; Sulfhydryl Compounds | 2013 |
An important role of matrix metalloproteinase-8 in angiogenesis in vitro and in vivo.
Topics: Aneurysm; Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; beta Catenin; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Gene Knockdown Techniques; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 8; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Neovascularization, Physiologic; Plaque, Atherosclerotic; Platelet Endothelial Cell Adhesion Molecule-1; RNA Interference; Time Factors; Transfection | 2013 |
Angiotensin (1-7) counteracts the negative effect of angiotensin II on insulin signalling in HUVECs.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mesenteric Arteries; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2013 |
Role of angiotensin II and angiotensin-(1-7) in diabetes-induced oxidative DNA damage in the corpus cavernosum.
Topics: Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; DNA Damage; Male; Oxidative Stress; Penis; Peptide Fragments; Proto-Oncogene Mas; Random Allocation; Rats; Rats, Wistar; Signal Transduction | 2013 |
Prolyl carboxypeptidase: a forgotten kidney angiotensinase. Focus on "Identification of prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry".
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Male; Peptide Fragments; Peptidyl-Dipeptidase A | 2013 |
Abrogation of ER stress-induced apoptosis of alveolar epithelial cells by angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Antineoplastic Agents; Apoptosis; Autocrine Communication; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Leupeptins; Peptide Fragments; Pulmonary Alveoli; Pulmonary Surfactant-Associated Protein C; Receptors, Angiotensin; Signal Transduction; Vasoconstrictor Agents | 2013 |
Angiotensin II induces endothelin-1 expression in human hepatic stellate cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Cells, Cultured; Endothelin-1; Hepatic Stellate Cells; Humans; Liver Cirrhosis; Renin-Angiotensin System | 2013 |
Ang(1-7) treatment attenuates β-cell dysfunction by improving pancreatic microcirculation in a rat model of Type 2 diabetes.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Insulin; Insulin Secretion; Islets of Langerhans; Male; Microcirculation; Nitric Oxide; Nitric Oxide Synthase Type III; Pancreas; Peptide Fragments; Rats; Rats, Wistar | 2013 |
ACE2 activation confers endothelial protection and attenuates neointimal lesions in prevention of severe pulmonary arterial hypertension in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Cytoprotection; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Activators; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Naphthalenes; Neointima; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resorcinols; Severity of Illness Index; Time Factors; Vasodilation | 2013 |
Antinociceptive response in transgenic mice expressing rat tonin.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Behavior, Animal; Disease Models, Animal; Losartan; Male; Mice; Mice, Transgenic; Nociception; Nociceptive Pain; Pain Measurement; Peptide Fragments; Rats; Receptors, G-Protein-Coupled; Tissue Kallikreins | 2013 |
Angiotensin-converting enzyme inhibitor does not suppress renal angiotensin II levels in angiotensin I-infused rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Imidazoles; Kidney; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Thiazepines | 2013 |
Differential mechanisms of activation of the Ang peptide receptors AT1, AT2, and MAS: using in silico techniques to differentiate the three receptors.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin III; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Sequence Data; Peptides; Peptidyl-Dipeptidase A; Protein Binding; Protein Interaction Domains and Motifs; Protein Transport; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Sequence Alignment; Structural Homology, Protein | 2013 |
Fetal sex and the circulating renin-angiotensin system during early gestation in women who later develop preeclampsia or gestational hypertension.
Topics: Adult; Angiotensin I; Angiotensin II; Biomarkers; Blood Pressure; Case-Control Studies; Female; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Pre-Eclampsia; Pregnancy; Renin; Renin-Angiotensin System; Risk Assessment; Risk Factors; Sex Determination Analysis; Sex Factors; Ultrasonography, Doppler; Ultrasonography, Prenatal; Young Adult | 2014 |
The renin angiotensin system regulates Kupffer cells in colorectal liver metastases.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Colorectal Neoplasms; Disease Models, Animal; Gadolinium; Kupffer Cells; Liver Neoplasms; Macrophages; Male; Mice; Mice, Inbred CBA; Peptide Fragments; Renin-Angiotensin System | 2013 |
Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion.
Topics: AMP-Activated Protein Kinases; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cardiomegaly; Hyperthyroidism; Imidazoles; Male; Myocardial Reperfusion Injury; Myocardium; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Thyroxine; Triiodothyronine; Ventricular Pressure | 2013 |
Angiotensin-[1-12] interacts with angiotensin type I receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation; Male; Membrane Potentials; Peptide Fragments; Phosphorylation; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Transfection | 2014 |
Contributions of leukocyte angiotensin-converting enzyme to development of atherosclerosis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atherosclerosis; Bone Marrow Transplantation; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Enalapril; Hypercholesterolemia; Leukocytes; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Receptors, LDL; Transplantation Chimera | 2013 |
AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chronic Disease; Cytokines; Disease Models, Animal; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Mice; Mice, Inbred BALB C; Molecular Mimicry; Ovalbumin; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Veins; Receptors, G-Protein-Coupled; Time Factors | 2013 |
Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Lipopolysaccharides; Losartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Receptors, G-Protein-Coupled; Respiratory Distress Syndrome; Vasodilator Agents | 2013 |
Protective effects of angiotensin-(1-7) administrated with an angiotensin-receptor blocker in a rat model of chronic kidney disease.
Topics: Angiopoietins; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Fibronectins; Losartan; Male; Nephrectomy; Peptide Fragments; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Receptor, TIE-2; Renal Insufficiency, Chronic; Systole | 2013 |
Angiotensin-(1-7) protects from experimental acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electric Impedance; Endothelial Cells; Hemodynamics; Imidazoles; Irbesartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Respiratory Mechanics; Tetrazoles | 2013 |
The effects of angiotensin II and angiotensin-(1-7) in the rostral ventrolateral medulla of rats on stress-induced hypertension.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Gene Expression Regulation; Heart Rate; Hypertension; Male; Medulla Oblongata; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stress, Psychological | 2013 |
Angiotensin (1-7) contributes to nitric oxide tonic inhibition of vasopressin release during hemorrhagic shock in acute ethanol intoxicated rodents.
Topics: Alcoholic Intoxication; Angiotensin I; Angiotensin II; Animals; Arginine Vasopressin; Enzyme Inhibitors; Hemodynamics; Injections, Intraventricular; Male; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Shock, Hemorrhagic; Up-Regulation | 2013 |
Role of angiotensin-(1-7) in gastroprotection against stress-induced ulcerogenesis. The involvement of mas receptor, nitric oxide, prostaglandins, and sensory neuropeptides.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Ulcer Agents; Capsaicin; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytokines; Denervation; Enzyme Inhibitors; Gastric Mucosa; Interleukin-1beta; Male; Neuropeptides; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Regional Blood Flow; Renin-Angiotensin System; Sensory Receptor Cells; Stomach; Stomach Ulcer; Tumor Necrosis Factor-alpha | 2013 |
Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biphenyl Compounds; Cardiomegaly; Cardiotonic Agents; Collagen; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Gene Expression Regulation; Irbesartan; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; PPAR alpha; PPAR delta; PPAR gamma; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Tetrazoles; Transforming Growth Factor beta | 2013 |
Endothelial metabolism of angiotensin II to angiotensin III, not angiotensin (1-7), augments the vasorelaxation response in adrenal cortical arteries.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Cattle; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Peptide Fragments; Vasodilation | 2013 |
Renin inhibition ameliorates renal damage through prominent suppression of both angiotensin I and II in human renin angiotensinogen transgenic mice with high salt loading.
Topics: Albuminuria; Amides; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Blood Pressure; Cytoprotection; Disease Models, Animal; Disease Progression; Down-Regulation; Fumarates; Humans; Hydralazine; Hypertension; Kidney; Kidney Diseases; Mice; Mice, Transgenic; Ramipril; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Time Factors | 2014 |
Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; bcl-X Protein; Bleomycin; Cells, Cultured; Collagen Type I; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Infusions, Subcutaneous; Lung; Male; MAP Kinase Signaling System; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pneumonia; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2014 |
Evaluation of a rapid pressor response test in healthy cats.
Topics: Administration, Intravenous; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Male; Vasoconstrictor Agents | 2013 |
[Expression and significance of ACE2-Ang-(1-7)-Mas axis in the endometrium of patients with polycystic ovary syndrome].
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Case-Control Studies; Endometrium; Female; Humans; Peptide Fragments; Peptidyl-Dipeptidase A; Polycystic Ovary Syndrome; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Young Adult | 2013 |
Angiotensin 1-7 improves insulin sensitivity by increasing skeletal muscle glucose uptake in vivo.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Glucose; Insulin Resistance; Male; Muscle, Skeletal; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2014 |
Angiotensin-(1-7) modulates renal vascular resistance through inhibition of p38 mitogen-activated protein kinase in apolipoprotein E-deficient mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apolipoproteins E; Atherosclerosis; Blood Pressure; Disease Models, Animal; Female; Hypertension, Renal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Naphthalenes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyrazoles; Receptors, G-Protein-Coupled; Renal Circulation; Vascular Resistance | 2014 |
Angiotensin (1-7) protects against stress-induced gastric lesions in rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cold Temperature; Corticosterone; H(+)-K(+)-Exchanging ATPase; Infusions, Intraventricular; Male; Norepinephrine; Peptide Fragments; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 2014 |
Enhanced angiotensin-converting enzyme activity and systemic reactivity to angiotensin II in normotensive rats exposed to a high-sodium diet.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sodium Chloride, Dietary | 2014 |
Angiotensin-converting enzyme (ACE and ACE2) imbalance correlates with the severity of cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Amylases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Ceruletide; Disease Models, Animal; Genotype; Inflammation Mediators; Male; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Pancreas; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Severity of Illness Index; Time Factors | 2014 |
Autocrine and paracrine function of Angiotensin 1-7 in tissue repair during hypertension.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Autocrine Communication; Disease Models, Animal; Fibrosis; Hypertension; Kidney; Male; Myocardium; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Signal Transduction; Ventricular Remodeling | 2014 |
Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diminazene; Disease Models, Animal; Glutamyl Aminopeptidase; Hypertension; Imidazoles; In Vitro Techniques; Kidney; Leucine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Xanthones | 2014 |
Novel role of aminopeptidase-A in angiotensin-(1-7) metabolism post myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Enzyme Inhibitors; Glutamyl Aminopeptidase; Kinetics; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Tandem Mass Spectrometry; Ventricular Remodeling | 2014 |
Recognition and neutralization of angiotensins I and II using an artificial nanogel receptor fabricated by ligand specificity determinant imprinting.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Ligands; Molecular Imprinting; Nanostructures; Rats; Receptors, Angiotensin | 2014 |
Angiotensin converting enzyme 2/Ang-(1-7)/mas axis protects brain from ischemic injury with a tendency of age-dependence.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Brain; Brain Edema; Brain Ischemia; Cell Death; Female; Glucose; Hypoxia, Brain; Infarction, Middle Cerebral Artery; Male; Membrane Glycoproteins; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Reactive Oxygen Species; Stroke; Tissue Culture Techniques | 2014 |
The Ang-(1-7)/Mas-1 axis attenuates the expression and signalling of TGF-β1 induced by AngII in mouse skeletal muscle.
Topics: Angiotensin I; Angiotensin II; Animals; Mice; Mice, Inbred C57BL; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Smad4 Protein; Transforming Growth Factor beta1 | 2014 |
Ulinastatin activates the renin-angiotensin system to ameliorate the pathophysiology of severe acute pancreatitis.
Topics: Acute Disease; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Ceruletide; Disease Models, Animal; Gene Expression; Glycoproteins; Lipopolysaccharides; Mice, Inbred C57BL; Molecular Targeted Therapy; Pancreatitis; Peptide Fragments; Peptidyl-Dipeptidase A; Prospective Studies; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Severity of Illness Index | 2014 |
Angiotensin-(1-7) attenuates angiotensin II-induced signalling associated with activation of a tyrosine phosphatase in Sprague-Dawley rats cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; CSK Tyrosine-Protein Kinase; Enzyme Activation; Fibroblasts; Mitogen-Activated Protein Kinases; Myocardium; Peptide Fragments; Phosphorylation; Primary Cell Culture; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats, Sprague-Dawley; Signal Transduction; src-Family Kinases | 2014 |
Female spontaneously hypertensive rats are more dependent on ANG (1-7) to mediate effects of low-dose AT1 receptor blockade than males.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hypertension; Male; Membrane Proteins; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sex Factors; Tetrazoles | 2014 |
Angiotensin-(1-7) recruits muscle microvasculature and enhances insulin's metabolic action via mas receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Arteries; Blood Flow Velocity; Blotting, Western; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Glucose; Hindlimb; Hypoglycemic Agents; In Vitro Techniques; Infusions, Intravenous; Insulin; Male; Microvessels; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Regional Blood Flow; Vasodilation | 2014 |
Angiotensin-(1-7) and angiotensin Ⅱ induce the transdifferentiation of human endometrial epithelial cells in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Cadherins; Cell Proliferation; Cell Transdifferentiation; Cells, Cultured; Collagen Type I; Endometrium; Epithelial Cells; Female; Fibronectins; Humans; Immunohistochemistry; Peptide Fragments | 2014 |
Angiotensin (1-7) prevents angiotensin II-induced nociceptive behaviour via inhibition of p38 MAPK phosphorylation mediated through spinal Mas receptors in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Behavior, Animal; Injections, Spinal; Mice; Nociceptive Pain; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Spinal Cord | 2014 |
Ang (1-7) protects islet endothelial cells from palmitate-induced apoptosis by AKT, eNOS, p38 MAPK, and JNK pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Cell Line, Transformed; Endothelium, Vascular; Enzyme Activation; Fatty Acids, Nonesterified; Islets of Langerhans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Microvessels; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Peptide Fragments; Protective Agents; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction | 2014 |
Activation of the ACE2/Ang-(1-7)/Mas pathway reduces oxygen-glucose deprivation-induced tissue swelling, ROS production, and cell death in mouse brain with angiotensin II overproduction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Brain; Brain Edema; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Cerebral Cortex; Glucose; Hypoxia; Membrane Glycoproteins; Mice, Transgenic; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Neurons; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Stroke; Tissue Culture Techniques | 2014 |
Angiotensin II and 1-7 during aging in Metabolic Syndrome rats. Expression of AT1, AT2 and Mas receptors in abdominal white adipose tissue.
Topics: Adipose Tissue, White; Aging; Angiotensin I; Angiotensin II; Animals; Gene Expression Regulation; Humans; Hypertension; Metabolic Syndrome; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2014 |
Angiotensin-(1-7) induces cerebral ischaemic tolerance by promoting brain angiogenesis in a Mas/eNOS-dependent pathway.
Topics: Angiogenesis Inhibitors; Angiotensin I; Angiotensin II; Animals; Brain; Cerebrovascular Circulation; Endostatins; Infarction, Middle Cerebral Artery; Male; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Ornithine; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled | 2014 |
Estrogen regulation of the brain renin-angiotensin system in protection against angiotensin II-induced sensitization of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Brain; Disease Models, Animal; Estradiol; Estrogen Replacement Therapy; Female; Gene Expression Regulation; Hypertension; Infusions, Intraventricular; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger; Sex Factors; Telemetry; Time Factors | 2014 |
Nuclear expression of renin-angiotensin system components in NRK-52E renal epithelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cattle; Cell Line; Cell Nucleus; Epithelial Cells; Kidney; Peptide Fragments; Prorenin Receptor; Protease Inhibitors; Rats; Receptors, Cell Surface; Renin; Renin-Angiotensin System; Sheep; Time Factors | 2015 |
Role of Mas receptor in renal blood flow response to angiotensin (1-7) in male and female rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Kidney; Male; Peptide Fragments; Perfusion; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renal Circulation; Renin-Angiotensin System; Sex Factors | 2014 |
Fetal and maternal angiotensin (1-7) are associated with preterm birth.
Topics: Adult; Angiotensin I; Angiotensin II; Female; Fetal Blood; Fetus; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Peptide Fragments; Pre-Eclampsia; Pregnancy; Premature Birth; Prospective Studies; Renin-Angiotensin System; Risk Factors; Term Birth | 2014 |
Dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Hypertension; Male; Peptide Fragments | 2014 |
Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiovascular Diseases; Hypertension; Male; Peptide Fragments | 2014 |
Effect of all-trans retinoic acid treatment on prohibitin and renin-angiotensin-aldosterone system expression in hypoxia-induced renal tubular epithelial cell injury.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Hypoxia; Collagen Type IV; Epithelial Cells; Fibronectins; Kidney Tubules; Oxidation-Reduction; Oxidative Stress; Peptidyl-Dipeptidase A; Prohibitins; Rats; Renin-Angiotensin System; Repressor Proteins; RNA, Messenger; Transforming Growth Factor beta1; Tretinoin | 2014 |
[Effect of tanshinone II(A) on expression of different components in renin-angiotensin system of left ventricles of hypertensive rats].
Topics: Abietanes; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Heart Ventricles; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2014 |
Beneficial effects of houttuynin on ventricular remodeling induced by coronary artery ligation in rats.
Topics: Aldehydes; Aldosterone; Angiotensin I; Angiotensin II; Animals; Catalase; Collagen; Coronary Vessels; Endothelin-1; Glutathione Peroxidase; Ligation; Male; Myocardium; Rats, Sprague-Dawley; Ventricular Remodeling | 2014 |
Angiotensin(1-7) attenuates the progression of streptozotocin-induced diabetic renal injury better than angiotensin receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Proliferation; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Male; Mesangial Cells; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Valsartan; Vascular Endothelial Growth Factor A | 2015 |
Angiotensin-(1-7) prevents angiotensin II-induced fibrosis in cremaster microvessels.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Chronic Disease; Connective Tissue Growth Factor; Dual Specificity Phosphatase 1; Fibrosis; Hypertension; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Muscle, Skeletal; Peptide Fragments; Phosphorylation; Rats; Rats, Inbred Lew; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta; Vasoconstrictor Agents | 2015 |
Angiotensin-(1-7) attenuates damage to podocytes induced by preeclamptic serum through MAPK pathways.
Topics: Actins; Adult; Angiotensin I; Angiotensin II; Apoptosis; Cell Survival; Female; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Podocytes; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2014 |
Inhibition of PKC-dependent extracellular Ca2+ entry contributes to the depression of contractile activity in long-term pressure-overloaded endothelium-denuded rat aortas.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Aortic Coarctation; Blood Pressure; Blotting, Western; Calcium; Chromatography, High Pressure Liquid; Endothelium, Vascular; Male; Muscle, Smooth, Vascular; Neuromuscular Depolarizing Agents; Phenylephrine; Potassium; Protein Kinase C; Radioimmunoassay; Rats, Wistar; Receptor, Angiotensin, Type 2; Vasoconstriction | 2014 |
The actions of the renin-angiotensin system on cardiovascular and osmoregulatory function in embryonic chickens (Gallus gallus domesticus).
Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Avian Proteins; Cardiovascular System; Catecholamines; Chick Embryo; Heart Rate; Kidney; Nicotinic Antagonists; Organogenesis; Osmoregulation; Renin-Angiotensin System; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2014 |
Combined suppression of the intrarenal and circulating vasoconstrictor renin-ACE-ANG II axis and augmentation of the vasodilator ACE2-ANG 1-7-Mas axis attenuates the systemic hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Age Factors; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Hypoxia; Kidney; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
Intrapulmonary activation of the angiotensin-converting enzyme type 2/angiotensin 1-7/G-protein-coupled Mas receptor axis attenuates pulmonary hypertension in Ren-2 transgenic rats exposed to chronic hypoxia.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Rats, Transgenic; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Signal Transduction; Vasoconstriction; Vasodilation | 2015 |
MSCs modified with ACE2 restore endothelial function following LPS challenge by inhibiting the activation of RAS.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Endothelial Cells; Genetic Therapy; HEK293 Cells; Humans; Lipopolysaccharides; Mesenchymal Stem Cells; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2015 |
Blood pressure-lowering peptides from neo-fermented buckwheat sprouts: a new approach to estimating ACE-inhibitory activity.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Fagopyrum; Fermentation; In Vitro Techniques; Male; Plant Extracts; Rats, Inbred SHR | 2014 |
Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Male; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Muscular Atrophy; Myosin Heavy Chains; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, G-Protein-Coupled; Signal Transduction; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases | 2015 |
Serine proteases as candidates for proteolytic processing of angiotensin-I converting enzyme.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Humans; Hypertension; Mesangial Cells; Peptidyl-Dipeptidase A; Protein Isoforms; Proteolysis; Rats; Serine Proteases | 2015 |
The angiotensin-(1-7)/Mas axis reduces myonuclear apoptosis during recovery from angiotensin II-induced skeletal muscle atrophy in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Disease Models, Animal; Immunoblotting; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Muscular Atrophy; Peptide Fragments; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2015 |
Changes in levels of angiotensin II and its receptors in a model of inverted stress-induced cardiomyopathy.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomyopathies; Disease Models, Animal; Female; Myocardium; Peptide Fragments; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Stress, Physiological | 2014 |
Angiotensin-(1-7) modulates angiotensin II-induced vasoconstriction in human mammary artery.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; Endothelium, Vascular; Female; Humans; Losartan; Male; Mammary Arteries; Middle Aged; Myocytes, Smooth Muscle; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Vasoconstriction | 2014 |
Ion collision crosssection measurements in quadrupole ion traps using a time-frequency analysis method.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Computer Simulation; Fourier Analysis; Mass Spectrometry; Models, Theoretical; Ubiquitin | 2014 |
Hyperbaric oxygenation modulates vascular reactivity to angiotensin-(1-7) in diabetic rats: potential role of epoxyeicosatrienoic acids.
Topics: 8,11,14-Eicosatrienoic Acid; Amides; Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Enzyme Induction; Enzyme Inhibitors; Hyperbaric Oxygenation; Male; Oxidative Stress; Peptide Fragments; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2015 |
Lack of renoprotective effect of chronic intravenous angiotensin-(1-7) or angiotensin-(2-10) in a rat model of focal segmental glomerulosclerosis.
Topics: Angiotensin I; Angiotensin II; Animals; Drug Administration Schedule; Glomerulosclerosis, Focal Segmental; HEK293 Cells; Humans; Hypertension; Injections, Intravenous; Male; Nephrectomy; Peptide Fragments; Podocytes; Radioligand Assay; Rats; Treatment Failure | 2014 |
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 1; Fibrosis; Gene Expression Regulation; Histological Techniques; Hypertension; Immunohistochemistry; Injections, Subcutaneous; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; Receptors, G-Protein-Coupled | 2015 |
Esophagoprotective activity of angiotensin-(1-7) in experimental model of acute reflux esophagitis. Evidence for the role of nitric oxide, sensory nerves, hypoxia-inducible factor-1alpha and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Animals; Cyclooxygenase 2; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-1beta; Male; Mucous Membrane; Nitric Oxide; Peptide Fragments; Protective Agents; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptors, G-Protein-Coupled; Regional Blood Flow; RNA, Messenger; Sensory Receptor Cells; Tumor Necrosis Factor-alpha | 2014 |
Angiotensin II can directly induce mitochondrial dysfunction, decrease oxidative fibre number and induce atrophy in mouse hindlimb skeletal muscle.
Topics: Angiotensin I; Angiotensin II; Animals; Caspase 3; DNA Nucleotidylexotransferase; Hindlimb; Male; Mice; Mice, Inbred C57BL; Mitochondria; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; NADPH Oxidases; Oxidation-Reduction; Renin-Angiotensin System | 2015 |
Ang (1-7) is a modulator of the vasoconstrictor actions of Ang I and Ang II.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; In Vitro Techniques; Male; Myocardial Infarction; Myocardium; Peptide Fragments; Rats, Wistar; Vasoconstrictor Agents | 2015 |
The effect of angiotensin-(1-7) in mouse unilateral ureteral obstruction.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Fibronectins; Male; Mice; Muscle, Smooth; Peptide Fragments; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 2015 |
Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-κB pathways.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Cells, Cultured; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Lung; MAP Kinase Signaling System; Microvessels; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Small Interfering; Signal Transduction | 2015 |
The association of renin-angiotensin system genes with the progression of hepatocellular carcinoma.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antigens, CD34; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Gene Expression Regulation, Neoplastic; Humans; Liver Cirrhosis; Liver Neoplasms; Peptide Fragments; Peptidyl-Dipeptidase A; Prognosis; Reference Values; Renin-Angiotensin System; Vascular Endothelial Growth Factor A | 2015 |
Angiotensin processing activities in the venom of Thalassophryne nattereri.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Animals; Batrachoidiformes; Bradykinin; Brazil; Chromatography, High Pressure Liquid; Disease Models, Animal; Fish Venoms; Fishes, Poisonous; Mice | 2015 |
Angiotensin II causes cellular proliferation in infantile haemangioma via angiotensin II receptor 2 activation.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cell Proliferation; Hemangioma; Humans; Infant; Ki-67 Antigen; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Tissue Culture Techniques | 2015 |
ACE2 and Ang-(1-7) protect endothelial cell function and prevent early atherosclerosis by inhibiting inflammatory response.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Cell Adhesion; Cell Movement; Chemokine CCL2; Disease Models, Animal; E-Selectin; Endothelium, Vascular; Gene Transfer Techniques; Humans; In Vitro Techniques; Inflammation; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
Functional and molecular evidence for expression of the renin angiotensin system and ADAM17-mediated ACE2 shedding in COS7 cells.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Base Sequence; Chlorocebus aethiops; COS Cells; Molecular Sequence Data; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; RNA Interference; RNA, Messenger; Transcription, Genetic; Transfection | 2015 |
Angiotensin-(1-7) protects against the development of aneurysmal subarachnoid hemorrhage in mice.
Topics: Aneurysm, Ruptured; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Brain; Cerebral Arteries; Cytokines; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Pyridines; Receptor, Angiotensin, Type 2; RNA, Messenger; Subarachnoid Hemorrhage | 2015 |
Early co-expression of cyclooxygenase-2 and renin in the rat kidney cortex contributes to the development of N(G)-nitro-L-arginine methyl ester induced hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Captopril; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypertension, Renal; Kidney Cortex; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Random Allocation; Rats, Wistar; Renin; RNA, Messenger | 2015 |
Angiotensin-(1-7) stimulates cholesterol efflux from angiotensin II-treated cholesterol-loaded THP-1 macrophages through the suppression of p38 and c-Jun N-terminal kinase signaling.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Cholesterol; Gene Expression Regulation, Enzymologic; Humans; JNK Mitogen-Activated Protein Kinases; Liver X Receptors; Macrophages; Orphan Nuclear Receptors; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; PPAR gamma; Renin-Angiotensin System; RNA, Messenger | 2015 |
Downregulation of the vascular renin-angiotensin system by aerobic training - focus on the balance between vasoconstrictor and vasodilator axes - .
Topics: Aerobiosis; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Femoral Artery; Kidney; Male; Organ Specificity; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin-Angiotensin System; Running; Vasoconstriction; Vasodilation | 2015 |
Development of a sensitive, accurate and robust liquid chromatography/mass spectrometric method for profiling of angiotensin peptides in plasma and its application for atherosclerotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Animals; Apolipoproteins E; Atherosclerosis; Chromatography, Liquid; Mass Spectrometry; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Receptors, LDL | 2015 |
Des-aspartate angiotensin I (DAA-I) reduces endothelial dysfunction in the aorta of the spontaneously hypertensive rat through inhibition of angiotensin II-induced oxidative stress.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Hypertension; Male; Organ Culture Techniques; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2015 |
Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Humans; Male; Mice; Mice, Inbred C57BL; Myocardium; Nitric Oxide Synthase Type III; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Signal Transduction | 2015 |
Lack of weight gain after angiotensin AT1 receptor blockade in diet-induced obesity is partly mediated by an angiotensin-(1-7)/Mas-dependent pathway.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Genetically Modified; Benzimidazoles; Benzoates; Diet; Energy Intake; Energy Metabolism; Insulin Resistance; Leptin; Male; Obesity; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Signal Transduction; Telmisartan; Weight Gain; Weight Loss | 2015 |
Angiotensin-(1-7) Attenuates Angiotensin II-Induced ICAM-1, VCAM-1, and MCP-1 Expression via the MAS Receptor Through Suppression of P38 and NF-κB Pathways in HUVECs.
Topics: Angiotensin I; Angiotensin II; Cells, Cultured; Chemokine CCL2; Human Umbilical Vein Endothelial Cells; Humans; I-kappa B Proteins; Intercellular Adhesion Molecule-1; NF-kappa B; NF-KappaB Inhibitor alpha; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Cell Adhesion Molecule-1 | 2015 |
Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Cytochrome P-450 Enzyme System; Disease Progression; Enzyme Inhibitors; Epoxide Hydrolases; Fatty Acids, Monounsaturated; Female; Fistula; Heart Failure; Heart Rate; Hemodynamics; Kidney; Male; Peptide Fragments; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Solubility; Time Factors; Vena Cava, Inferior | 2015 |
Intracellular angiotensin (1-7) increases the inward calcium current in cardiomyocytes. On the role of PKA activation.
Topics: Angiotensin I; Angiotensin II; Animals; Calcium; Calcium Channels; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Heart Ventricles; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Inbred WKY | 2015 |
Activation of angiotensin-(1-7)/Mas axis in the brain lowers blood pressure and attenuates cardiac remodeling in hypertensive transgenic (mRen2)27 rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Heart; Heart Rate; Hypertension; Male; Myocardium; Peptide Fragments; Rats, Sprague-Dawley; Rats, Transgenic; Renin-Angiotensin System; RNA, Messenger | 2015 |
Angiotensin (1-7), small but complicated, needs more exercise.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Kidney; Male; Peptide Fragments; Physical Conditioning, Animal; Renal Artery; Renin-Angiotensin System | 2015 |
ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cytokines; Dependovirus; Disease Models, Animal; Enzyme Activation; Gene Expression; Genetic Therapy; Genetic Vectors; Hepatic Stellate Cells; Inflammation Mediators; Injections, Intraperitoneal; Lipid Peroxidation; Liver Cirrhosis; Liver Function Tests; Male; MAP Kinase Signaling System; Methoxamine; Mice; NADPH Oxidases; Neovascularization, Pathologic; Organ Specificity; Oxidative Stress; Peptidyl-Dipeptidase A; RNA, Messenger | 2015 |
Angiotensin II type 1 receptor-associated protein plays a role in regulating the local renin-angiotensin system in HSC-T6 cells.
Topics: Angiotensin I; Angiotensin II; Animals; Cell Line; Gene Expression Regulation; Peptide Fragments; Rats; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger | 2015 |
A different role of angiotensin II type 1a receptor in the development and hypertrophy of plantaris muscle in mice.
Topics: Angiotensin I; Angiotensin II; Animals; Gene Expression; Hypertrophy; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Receptor, Angiotensin, Type 1; RNA, Messenger; SKP Cullin F-Box Protein Ligases | 2016 |
Inhibition of soluble epoxide hydrolase does not improve the course of congestive heart failure and the development of renal dysfunction in rats with volume overload induced by aorto-caval fistula.
Topics: 8,11,14-Eicosatrienoic Acid; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzoates; Disease Models, Animal; Drug Evaluation, Preclinical; Epoxide Hydrolases; Epoxy Compounds; Heart Failure; Kidney; Male; Myocardium; Peptide Fragments; Random Allocation; Rats; Renal Insufficiency; Renin-Angiotensin System; Ultrasonography; Urea | 2015 |
Differential expression of the angiotensin-(1-12)/chymase axis in human atrial tissue.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensinogen; Atrial Fibrillation; Chymases; Echocardiography; Female; Gene Expression Regulation, Enzymologic; Heart Atria; Heart Valve Diseases; Humans; Male; Middle Aged; Myocardial Ischemia; RNA, Messenger; Up-Regulation; Ventricular Remodeling | 2015 |
Malaria in Pregnancy Interacts with and Alters the Angiogenic Profiles of the Placenta.
Topics: Angiotensin I; Angiotensin II; Brazil; Cross-Sectional Studies; Cytokines; Enzyme-Linked Immunosorbent Assay; Epidemiological Monitoring; Female; Humans; Malaria; Neovascularization, Physiologic; Placenta; Pregnancy; Prevalence; Receptor, TIE-2; Statistics, Nonparametric | 2015 |
Angiotensin-(1-7) counteracts angiotensin II-induced dysfunction in cerebral endothelial cells via modulating Nox2/ROS and PI3K/NO pathways.
Topics: Angiotensin I; Angiotensin II; Apoptosis; Blotting, Western; Brain; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation; Humans; Microvessels; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Vasoconstrictor Agents; Vasodilator Agents | 2015 |
Baicalin attenuates angiotensin II-induced endothelial dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aorta, Thoracic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Flavonoids; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Signal Transduction; Tissue Culture Techniques; Vasodilation | 2015 |
Long-Term Regulation of the Local Renin-Angiotensin System in the Myocardium of Spontaneously Hypertensive Rats by Feeding Bioactive Peptides Derived from Spirulina platensis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Male; Myocardium; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spirulina | 2015 |
Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Gene Deletion; Humans; Inflammation; Kidney; Male; Membrane Proteins; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 1; Receptors, Tumor Necrosis Factor, Type I; Recombinant Proteins; Signal Transduction; Superoxides; Tumor Necrosis Factor-alpha | 2015 |
Antibody-free ultra-high performance liquid chromatography/tandem mass spectrometry measurement of angiotensin I and II using magnetic epitope-imprinted polymers.
Topics: Acrylamides; Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Chromatography, Liquid; Epitopes; Feasibility Studies; Humans; Magnetite Nanoparticles; Molecular Imprinting; Polymethacrylic Acids; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2015 |
Angiotensin-(1-7) counteracts the effects of Ang II on vascular smooth muscle cells, vascular remodeling and hemorrhagic stroke: Role of the NFкB inflammatory pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Movement; Cell Proliferation; Cells, Cultured; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Infarction, Middle Cerebral Artery; Inflammation Mediators; Intracranial Hemorrhages; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neuroprotective Agents; NF-kappa B; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction; Vascular Remodeling; Wound Healing | 2015 |
Maternal hyperthyroidism increases the susceptibility of rat adult offspring to cardiovascular disorders.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Newborn; Disease Models, Animal; Disease Susceptibility; Female; Hypertension; Hyperthyroidism; Male; Myocardial Reperfusion Injury; Plethysmography; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Thyroxine | 2015 |
ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antigens, CD34; Cell Adhesion; Cell Movement; Cell Proliferation; Diminazene; Humans; Leukocytes, Mononuclear; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents; Wound Healing; Xanthones | 2015 |
Differential control of vasomotion by angiotensins in the rostral ventrolateral medulla of hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Blood Pressure; Cardiac Output; Cerebrovascular Circulation; Heart Rate; Male; Medulla Oblongata; Mesenteric Arteries; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Vascular Resistance | 2015 |
[Telmisartan reduces retina vessel endothelial cell apoptosis via upregulating retinal ACE2-Ang-(1-7)-Mas axis in spontaneous hypertensive rats].
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Benzimidazoles; Benzoates; Blood Pressure; Endothelial Cells; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Retina; Systole; Telmisartan; Up-Regulation | 2015 |
Angiotensin-(1-7) enhances the effects of angiotensin II on the cardiac sympathetic afferent reflex and sympathetic activity in rostral ventrolateral medulla in renovascular hypertensive rats.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Disease Models, Animal; Drug Interactions; Hypertension, Renovascular; Losartan; Male; Medulla Oblongata; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Reflex; Sympathetic Nervous System; Treatment Outcome | 2015 |
Effect of angiotensin-(1-7) and angiotensin II on the proliferation and activation of human endometrial stromal cells in vitro.
Topics: Actins; Angiotensin I; Angiotensin II; Cell Proliferation; Collagen Type I; Endometrium; Female; Fibronectins; Humans; Insulin-Like Growth Factor I; Peptide Fragments; Stromal Cells; Transforming Growth Factor beta1 | 2015 |
Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Cell Line; Kidney; Kidney Diseases; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2015 |
Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options.
Topics: Adolescent; Aldosterone; Angiotensin I; Angiotensin II; Angiotensins; Arterial Pressure; Blood Pressure; Catecholamines; Child; Diastole; Dopamine; Epinephrine; Female; Heart Rate; Humans; Hypotension, Orthostatic; Male; Norepinephrine; Orthostatic Intolerance; Postural Orthostatic Tachycardia Syndrome; Prospective Studies; Renin; Syncope; Systole; Tilt-Table Test; Vasopressins | 2016 |
The effect of angiotensin-converting enzyme inhibition throughout a superovulation protocol in ewes.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Embryo, Nonmammalian; Enalapril; Estradiol; Female; Ovulation; Peptide Fragments; Peptidyl-Dipeptidase A; Progesterone; Sheep; Superovulation | 2015 |
Angiotensin 1-7 Protects against Angiotensin II-Induced Endoplasmic Reticulum Stress and Endothelial Dysfunction via Mas Receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Endothelium; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Tunicamycin | 2015 |
Two-dimensional honeycomb network through sequence-controlled self-assembly of oligopeptides.
Topics: Angiotensin I; Angiotensin II; Microscopy, Scanning Tunneling; Molecular Dynamics Simulation; Nanostructures; Oligopeptides; Peptides; Protein Conformation | 2016 |
Osthole Alleviates Bleomycin-Induced Pulmonary Fibrosis via Modulating Angiotensin-Converting Enzyme 2/Angiotensin-(1-7) Axis and Decreasing Inflammation Responses in Rats.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents; Bleomycin; Collagen; Coumarins; Cytokines; Edema; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Pulmonary Fibrosis; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2016 |
Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cardiovascular System; Chromatography, High Pressure Liquid; Citrate (si)-Synthase; Hypertension; Male; Medulla Oblongata; Oxidative Stress; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species; Renin-Angiotensin System; Signal Transduction | 2016 |
The renin-angiotensin system and its vasoactive metabolite angiotensin-(1-7) in the mechanism of the healing of preexisting gastric ulcers. The involvement of Mas receptors, nitric oxide, prostaglandins and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cytokines; Enzyme Inhibitors; Gastric Mucosa; Imidazoles; Indomethacin; Interleukin-1beta; Lisinopril; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Renal hemodynamics and renin-angiotensin system activity in humans with multifocal renal artery fibromuscular dysplasia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Case-Control Studies; Enzyme Inhibitors; Essential Hypertension; Female; Fibromuscular Dysplasia; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renovascular; Male; Microvessels; Middle Aged; Nitric Oxide Synthase; Peptide Fragments; Renal Artery; Renal Circulation; Renin; Renin-Angiotensin System; Sex Factors | 2016 |
Peroxisome proliferator-activated receptor-α stimulation by clofibrate favors an antioxidant and vasodilator environment in a stressed left ventricle.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antioxidants; Aortic Coarctation; Captopril; Catalase; Clofibrate; Drug Synergism; Heart Ventricles; Hypertension; Lipid Peroxidation; Male; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; PPAR alpha; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Superoxide Dismutase; Vasodilation | 2016 |
Dietary peptides from the non-digestible fraction of Phaseolus vulgaris L. decrease angiotensin II-dependent proliferation in HCT116 human colorectal cancer cells through the blockade of the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Catalytic Domain; Cell Culture Techniques; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Digestion; HCT116 Cells; Humans; Inhibitory Concentration 50; Models, Biological; Molecular Docking Simulation; Peptides; Peptidyl-Dipeptidase A; Phaseolus; Plant Extracts; Renin; Renin-Angiotensin System | 2016 |
Alternative pathways for angiotensin II production as an important determinant of kidney damage in endotoxemia.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Endotoxemia; Kidney; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin; Renin-Angiotensin System | 2016 |
Identification of dipeptidyl peptidase 3 as the Angiotensin-(1-7) degrading peptidase in human HK-2 renal epithelial cells.
Topics: Angiotensin I; Angiotensin II; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Epithelial Cells; Humans; Hydrolysis; Kidney; Oligopeptides; Peptide Fragments; Reactive Oxygen Species | 2016 |
The Renin-Angiotensin-Aldosterone System in Smokers and Non-Smokers of the Ludwigshafen Risk and Cardiovascular Health (LURIC) Study.
Topics: Aged; Aldosterone; Angiotensin I; Angiotensin II; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Female; Humans; Male; Middle Aged; Prognosis; Prospective Studies; Renin; Renin-Angiotensin System; Smoking; Survival Rate | 2016 |
Serum angiotensin-converting enzyme 2 concentration and angiotensin-(1-7) concentration in patients with acute heart failure patients requiring emergency hospitalization.
Topics: Acute Disease; Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Blood Pressure; Case-Control Studies; Emergencies; Female; Heart Failure; Hospitalization; Humans; Japan; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Regression Analysis; Renin; Renin-Angiotensin System | 2017 |
Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats.
Topics: 8,11,14-Eicosatrienoic Acid; Albuminuria; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cytochrome P-450 CYP1A1; Hypertension, Malignant; Indoles; Kidney; Male; Peptide Fragments; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Time Factors | 2016 |
Imbalance between angiotensin II and angiotensin-(1-7) in human coronary atherosclerosis.
Topics: Angiotensin I; Angiotensin II; Atherosclerosis; Coronary Artery Disease; Female; Humans; Male; Middle Aged; Peptide Fragments; Tumor Necrosis Factor-alpha | 2016 |
Angiotensin(1-7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H2O2-activated NLRP3 inflammasome/IL-1β/Smad circuit.
Topics: Angiotensin I; Angiotensin II; Animals; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Epithelial-Mesenchymal Transition; Gene Expression; Hepatocytes; Humans; Hydrogen Peroxide; Inflammasomes; Interleukin-1beta; Liver Cirrhosis; Male; Mice; NADPH Oxidase 4; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Rats, Wistar; Signal Transduction; Smad Proteins | 2016 |
Primacy of cardiac chymase over angiotensin converting enzyme as an angiotensin-(1-12) metabolizing enzyme.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Chymases; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR | 2016 |
Neuroinflammatory mechanisms of hypertension: potential therapeutic implications.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Blood-Brain Barrier; Cytokines; Humans; Hypertension; Inflammation; Lipopolysaccharides; Microglia; NF-kappa B; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Renin; Toll-Like Receptor 4 | 2016 |
The kinetics of angiotensin-I metabolism in human carotid atheroma: An emerging role for angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Carotid Artery Diseases; Chromatography, High Pressure Liquid; Disease Progression; Humans; Mass Spectrometry; Peptide Fragments; Plaque, Atherosclerotic; Time Factors | 2016 |
Renin-angiotensin system in ventilator-induced diaphragmatic dysfunction: Potential protective role of Angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Animals; Cell Membrane; Diaphragm; Humans; Insulin-Like Growth Factor I; Mice; Models, Theoretical; Muscle, Skeletal; Muscular Diseases; Oxidative Stress; Peptide Fragments; Rats; Renin-Angiotensin System; Respiration, Artificial | 2016 |
Antenatal corticosteroids and the renin-angiotensin-aldosterone system in adolescents born preterm.
Topics: Adolescent; Adrenal Cortex Hormones; Angiotensin I; Angiotensin II; Cohort Studies; Female; Fetal Organ Maturity; Humans; Infant, Newborn; Infant, Premature; Male; Peptide Fragments; Pregnancy; Prenatal Exposure Delayed Effects; Renin; Renin-Angiotensin System | 2017 |
Neprilysin is a Mediator of Alternative Renin-Angiotensin-System Activation in the Murine and Human Kidney.
Topics: Aminobutyrates; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Biopsy; Biphenyl Compounds; Female; Gene Expression; Humans; Immunohistochemistry; Kidney; Kidney Cortex; Mice; Mice, Knockout; Neprilysin; Peptide Fragments; Peptidyl-Dipeptidase A; Renin; Renin-Angiotensin System | 2016 |
Exogenous melatonin reduced blood pressure in late-term ovine fetus via MT1/MT2 receptor pathways.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenocorticotropic Hormone; Aldosterone; Angiotensin I; Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Corticotropin-Releasing Hormone; Endothelins; Fetus; Heart Rate; Hydrocortisone; Melatonin; Prazosin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sheep; Sheep, Domestic; Signal Transduction; Tryptamines | 2016 |
A Novel Mechanism of Action for Angiotensin-(1-7) via the Angiotensin Type 1 Receptor.
Topics: Angiotensin I; Angiotensin II; Humans; Peptide Fragments; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2016 |
Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Abdominal; beta-Arrestins; Cardiotonic Agents; Cells, Cultured; HEK293 Cells; Humans; Muscles; Peptide Fragments; Phenylephrine; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Sensitivity and Specificity; Signal Transduction; Vasoconstriction | 2016 |
Cross-talk between AMP-activated protein kinase and renin-angiotensin system in uninephrectomised rats.
Topics: AMP-Activated Protein Kinases; Angiotensin I; Angiotensin II; Animals; Enzyme Activation; Fluorescent Antibody Technique; Kidney; Male; Microscopy, Confocal; Nephrectomy; Phosphorylation; Rats, Sprague-Dawley; Renin-Angiotensin System | 2016 |
First Report of
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bradykinin; Eurycoma; Kallikrein-Kinin System; Male; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Vasodilator Agents | 2016 |
The Interplay between the Renin Angiotensin System and Pacing Postconditioning Induced Cardiac Protection.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Cardiac Pacing, Artificial; Heart; Hemodynamics; Irbesartan; Male; Myocardial Reperfusion Injury; Myocardium; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles | 2016 |
Chymase-dependent production of angiotensin II: an old enzyme in old hearts.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blotting, Western; Chymases; Enzyme-Linked Immunosorbent Assay; Myocardium; NADPH Oxidases; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Superoxides | 2017 |
Adhesion ability of angiotensin II with model membranes.
Topics: Amino Acids; Angiotensin I; Angiotensin II; Binding Sites; Histidine; Humans; Membranes; Molecular Weight; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Protein Binding; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System | 2017 |
Angiotensin-converting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Angiotensin I; Angiotensin II; Apolipoproteins E; Autopsy; Brain; Case-Control Studies; Cohort Studies; Female; Humans; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Polymorphism, Single Nucleotide; Statistics as Topic; tau Proteins | 2016 |
Exercise modulates the aortic renin-angiotensin system independently of estrogen therapy in ovariectomized hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Estradiol; Estrogens; Exercise Therapy; Humans; Hypertension; Ovariectomy; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Renin-Angiotensin System | 2017 |
Effects of exendin-4 on the intrarenal renin-angiotensin system and interstitial fibrosis in unilateral ureteral obstruction mice: Exendin-4 and unilateral ureteral obstruction.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen Type I; Exenatide; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred BALB C; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1; Ureteral Obstruction; Venoms | 2016 |
Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Autoantigens; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Kidney; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A; Recombinant Proteins; Time Factors | 2017 |
Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Endothelial Cells; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Male; Middle Cerebral Artery; Neovascularization, Physiologic; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2017 |
Positive association between KCNJ5 rs2604204 (A/C) polymorphism and plasma aldosterone levels, but also plasma renin and angiotensin I and II levels, in newly diagnosed hypertensive Chinese: a case-control study.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure Monitoring, Ambulatory; Case-Control Studies; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Gene Frequency; Genotype; Humans; Hypertension; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Renin | 2017 |
Vascular Reactivity of Isolated Aorta to Study the Angiotensin-(1-7) Actions.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Aorta; In Vitro Techniques; Mice; Peptide Fragments; Phenylephrine; Rats; Vasodilation; Vasodilator Agents | 2017 |
Prolylcarboxypeptidase deficiency is associated with increased blood pressure, glomerular lesions, and cardiac dysfunction independent of altered circulating and cardiac angiotensin II.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Carboxypeptidases; Kidney; Kidney Glomerulus; Kidney Tubules, Collecting; Male; Mice; Mice, Mutant Strains; Myocardium; Peptide Fragments | 2017 |
Screening of inhibitors of angiotensin-converting enzyme (ACE) employing high performance liquid chromatography-electrospray ionization triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Calibration; Chromatography, High Pressure Liquid; Lisinopril; Peptides; Peptidyl-Dipeptidase A; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2017 |
Effects of Root Extracts of Eurycoma longifolia Jack on Corpus Cavernosum of Rat.
Topics: Angiotensin I; Angiotensin II; Animals; Eurycoma; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Penis; Peptidyl-Dipeptidase A; Phenylephrine; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley | 2017 |
Angiotensin II/Angiotensin (1-7) ratio and 24-h blood pressure throughout the menstrual cycle and in women using oral contraceptives.
Topics: Adolescent; Adult; Angiotensin I; Angiotensin II; Blood Pressure; Contraceptives, Oral; Estradiol; Female; Humans; Menstrual Cycle; Peptide Fragments; Progesterone; Renin-Angiotensin System; Young Adult | 2017 |
Angiotensin-(1-7) regulates angiotensin II-induced matrix metalloproteinase-8 in vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Animals; Atherosclerosis; Cells, Cultured; Disease Models, Animal; Enzyme Activation; Humans; Matrix Metalloproteinase 8; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Plaque, Atherosclerotic; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Time Factors | 2017 |
Chronic overexpression of angiotensin-(1-7) in rats reduces cardiac reactivity to acute stress and dampens anxious behavior.
Topics: Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Anxiety; Heart Rate; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Stress, Psychological | 2017 |
A Fluorometric Method of Measuring Carboxypeptidase Activities for Angiotensin II and Apelin-13.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carboxypeptidases; Fluorometry; HEK293 Cells; Humans; Immunoassay; Intercellular Signaling Peptides and Proteins; Kidney; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylalanine; Substrate Specificity | 2017 |
Angiotensin-(1-7) attenuates angiotensin II-induced cardiac hypertrophy via a Sirt3-dependent mechanism.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cardiomegaly; Cardiotonic Agents; Cell Size; Fibrosis; Male; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Sirtuins; Superoxide Dismutase | 2017 |
The ACE-2/Ang1-7/Mas cascade enhances bone structure and metabolism following angiotensin-II type 1 receptor blockade.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Female; Femur; Losartan; Minerals; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
Anti-inflammatory action of angiotensin 1-7 in experimental colitis may be mediated through modulation of serum cytokines/chemokines and immune cell functions.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Movement; Chemokines; Chemotaxis; Colitis; Colon; Cytokines; Dextran Sulfate; Immunity, Cellular; Immunomodulation; Mice; Mice, Inbred BALB C; Models, Animal; Neutrophils; Peptide Fragments; Renin-Angiotensin System; Superoxides | 2017 |
Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cerebral Ventricles; Genotype; Humans; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Renin; Renin-Angiotensin System; Subfornical Organ; Time Factors; Up-Regulation | 2017 |
Reduced anxiety-like behavior in transgenic rats with chronically overproduction of angiotensin-(1-7): Role of the Mas receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Anxiety; Behavior, Animal; Imidazoles; Peptide Fragments; Pyridines; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2017 |
ACE-2/Ang1-7/Mas cascade mediates ACE inhibitor, captopril, protective effects in estrogen-deficient osteoporotic rats.
Topics: Administration, Oral; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Captopril; Delayed-Action Preparations; Female; Femur; Humans; Osteolysis; Osteoporosis, Postmenopausal; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Spectrophotometry, Atomic; X-Ray Microtomography | 2017 |
DRILL: An Electrospray Ionization-Mass Spectrometry Interface for Improved Sensitivity via Inertial Droplet Sorting and Electrohydrodynamic Focusing in a Swirling Flow.
Topics: Angiotensin I; Angiotensin II; Chromatography, High Pressure Liquid; Humans; Isotope Labeling; Limit of Detection; Peptides; Spectrometry, Mass, Electrospray Ionization | 2017 |
Exercise training modulates the hepatic renin-angiotensin system in fructose-fed rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Fatty Liver; Fructose; Gluconeogenesis; Interleukin-6; Lipid Metabolism; Liver; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tumor Necrosis Factor-alpha | 2017 |
Angiotensin 1-7 inhibits angiotensin II-stimulated head and neck cancer progression.
Topics: Angiotensin I; Angiotensin II; Cell Culture Techniques; Cell Movement; Disease Progression; Fibroblasts; Head and Neck Neoplasms; Humans; Immunoblotting; Peptide Fragments; Polymerase Chain Reaction; Renin-Angiotensin System; Signal Transduction; Transfection; Tumor Cells, Cultured | 2017 |
The ACE2-Ang (1-7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Collagen; Fibrosis; Heart Function Tests; Immunohistochemistry; Male; Myocardial Infarction; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Ventricular Dysfunction, Left; Ventricular Remodeling | 2017 |
Genetic Interference With Endothelial PPAR-γ (Peroxisome Proliferator-Activated Receptor-γ) Augments Effects of Angiotensin II While Impairing Responses to Angiotensin 1-7.
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Animals, Genetically Modified; Carotid Arteries; Female; Interleukin-6; Male; Mice; NF-kappa B; Oxidative Stress; Peptide Fragments; PPAR gamma; Pyridines; Renin-Angiotensin System; Vascular Diseases; Vasoconstrictor Agents; Vasodilation | 2017 |
Angiotensin‑(1‑7) attenuates caerulein‑induced pancreatic acinar cell apoptosis.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Ceruletide; Mice; Pancreas; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2017 |
Vasodilator Effect of Angiotensin-(1-7) on Vascular Coronary Bed of Rats: Role of Mas, ACE and ACE2.
Topics: Angiotensin I; Angiotensin II; Animals; Coronary Vessels; Heart; Humans; In Vitro Techniques; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Vasodilation; Vasodilator Agents | 2017 |
BML-111 equilibrated ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis to protect hepatic fibrosis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Down-Regulation; Heptanoic Acids; Liver Cirrhosis; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Up-Regulation | 2017 |
Angiotensin-(1-7) in Paraventricular Nucleus Contributes to the Enhanced Cardiac Sympathetic Afferent Reflex and Sympathetic Activity in Chronic Heart Failure Rats.
Topics: Acetophenones; Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Capsaicin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Heart Failure; Hemodynamics; Kidney; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Sprague-Dawley; Signal Transduction; Spin Labels; Superoxides; Sympathetic Nervous System | 2017 |
Intrarenal Mas and AT
Topics: Anesthesia, General; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Diet, Sodium-Restricted; Glomerular Filtration Rate; Hemodynamics; Infusions, Parenteral; Kidney; Losartan; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renal Circulation; Renal Elimination; Renin-Angiotensin System; Signal Transduction; Sodium, Dietary | 2017 |
Angiotensinergic Innervation of the Human Right Atrium: Implications for Cardiac Reflexes.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensins; Autonomic Nervous System; Heart Atria; Humans; Male; Middle Aged; Nerve Fibers; Peptide Fragments; Reflex; Synaptophysin; Tyrosine 3-Monooxygenase | 2018 |
Angiotensin 1-7 in the rostro-ventrolateral medulla increases blood pressure and splanchnic sympathetic nerve activity in anesthetized rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine Triphosphate; Angiotensin I; Angiotensin II; Animals; Astrocytes; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Rats, Sprague-Dawley; Receptors, Glutamate; Splanchnic Nerves; Sympathetic Nervous System; Sympatholytics; Sympathomimetics | 2018 |
Mir-21 Mediates the Inhibitory Effect of Ang (1-7) on AngII-induced NLRP3 Inflammasome Activation by Targeting Spry1 in lung fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Apoptosis; Bleomycin; Cells, Cultured; Collagen Type I; Fibroblasts; Inflammasomes; Lung; Male; MAP Kinase Signaling System; MicroRNAs; Nerve Tissue Proteins; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Peptide Hormones; Pulmonary Fibrosis; Rats; Rats, Wistar; Signal Transduction | 2017 |
Paracrine and Intracrine Angiotensin 1-7/Mas Receptor Axis in the Substantia Nigra of Rodents, Monkeys, and Humans.
Topics: Aging; Angiotensin I; Angiotensin II; Animals; Astrocytes; Case-Control Studies; Cell Nucleus; Cells, Cultured; Dopaminergic Neurons; Gene Deletion; Haplorhini; Male; Mesencephalon; Microglia; Mitochondria; Models, Biological; Neuroprotection; Oxidative Stress; Paracrine Communication; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Nitrogen Species; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Rodentia; Signal Transduction; Substantia Nigra | 2018 |
Obligatory Metabolism of Angiotensin II to Angiotensin III for Zona Glomerulosa Cell-Mediated Relaxations of Bovine Adrenal Cortical Arteries.
Topics: Abattoirs; Adrenal Cortex; Aldosterone; Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Arterioles; Cattle; Cells, Cultured; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; In Vitro Techniques; Muscle, Smooth, Vascular; Peptide Fragments; Protease Inhibitors; Vasodilation; Zona Glomerulosa | 2018 |
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Imidazoles; Inflammation; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways.
Topics: ADAM17 Protein; Adaptor Proteins, Signal Transducing; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Apoptosis; beta Catenin; Cardiomegaly; Cell Proliferation; Disease Models, Animal; Fibroblasts; Fibrosis; Glycogen Synthase Kinase 3 beta; Inflammation; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinases; Mice, Inbred C57BL; Peptide Fragments; Peptidyl-Dipeptidase A; Perfusion; Phosphorylation; Signal Transduction; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Angiotensin-(1-7) and Vascular Function: The Clinical Context.
Topics: Angiotensin I; Angiotensin II; Humans; Muscle, Smooth, Vascular; Peptide Fragments | 2018 |
The evolving role of the renin-angiotensin system in ARDS.
Topics: Angiotensin I; Angiotensin II; Humans; Renin; Renin-Angiotensin System | 2017 |
Angiotensin 1-7 ameliorates caerulein-induced inflammation in pancreatic acinar cells by downregulating Toll-like receptor 4/nuclear factor-κB expression.
Topics: Acinar Cells; Angiotensin I; Angiotensin II; Animals; Cell Line; Ceruletide; Down-Regulation; Inflammation; Interleukin-10; Interleukin-6; Microscopy, Fluorescence; NF-kappa B; Peptide Fragments; Rats; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Homocysteine directly interacts and activates the angiotensin II type I receptor to aggravate vascular injury.
Topics: Allosteric Regulation; Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; HEK293 Cells; Homocysteine; Humans; Male; Mice, Inbred C57BL; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Protein Conformation; Receptor, Angiotensin, Type 1; Vascular System Injuries | 2018 |
Modulating Role of Ang1-7 in Control of Blood Pressure and Renal Function in AngII-infused Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Hypertension; Male; Natriuresis; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction; Urodynamics | 2018 |
Direct renin inhibition is not enough to prevent reactive oxygen species generation and vascular dysfunction in renovascular hypertension.
Topics: Amides; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Drug Synergism; Fumarates; Hypertension, Renovascular; Losartan; Male; Nitrites; Oxidative Stress; Rats; Reactive Oxygen Species; Relaxation; Renin | 2018 |
Combined maternal and postnatal high-fat diet leads to metabolic syndrome and is effectively reversed by resveratrol: a multiple-organ study.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Diet, High-Fat; Female; Glucose Tolerance Test; Male; Maternal Nutritional Physiological Phenomena; Metabolic Syndrome; Obesity; Pregnancy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Resveratrol; Sirtuin 1; Triglycerides | 2018 |
[ACE2 agonist DIZE alleviates lung injury induced by limb ischemia-reperfusion in mice].
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Hindlimb; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Reperfusion Injury | 2018 |
FGF21 Prevents Angiotensin II-Induced Hypertension and Vascular Dysfunction by Activation of ACE2/Angiotensin-(1-7) Axis in Mice.
Topics: Adipose Tissue; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular System; Fibroblast Growth Factors; Hypertension; Kidney; Loss of Function Mutation; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Link between FGF21 and blood pressure.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Fibroblast Growth Factors; Humans; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
FGF21 ACEs hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Fibroblast Growth Factors; Hypertension; Mice; Peptide Fragments; Peptidyl-Dipeptidase A | 2018 |
Lower circulating levels of angiotensin-converting enzyme (ACE) in patients with schizophrenia.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Schizophrenia | 2018 |
[Role of mesenteric lymph drainage in the balance of ACE/ACE2 in murine myocardium following hemorrhagic shock].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drainage; Fluid Therapy; Lymph; Lymph Nodes; Male; Mesentery; Mice; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Resuscitation; Shock, Hemorrhagic | 2017 |
Angiotensin (1-7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; Arrestins; beta-Arrestins; Cell Line; CHO Cells; Cricetulus; Endothelial Cells; GTP-Binding Proteins; HEK293 Cells; Humans; Mitogen-Activated Protein Kinases; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Lipoxin A
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line, Tumor; Disease Models, Animal; Humans; Imidazoles; Leucine; Lipopolysaccharides; Lipoxins; Male; Mice; NF-kappa B; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drugs, Chinese Herbal; Escherichia coli; Escherichia coli Infections; Gene Expression Regulation; Male; Mice; Mice, Inbred ICR; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2018 |
Perindopril ameliorates lipopolysaccharide-induced brain injury through modulation of angiotensin-II/angiotensin-1-7 and related signaling pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Brain; Brain Injuries; Glutathione; Lipopolysaccharides; Male; Malondialdehyde; Peptide Fragments; Perindopril; Rats; Rats, Wistar; Signal Transduction; Transcription Factor RelA | 2018 |
Dynamics of Renin, Angiotensin II, and Angiotensin (1-7) during Pregnancy and Predisposition to Hypertension-Associated Complications.
Topics: Adult; Angiotensin I; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Middle Aged; Peptide Fragments; Pregnancy; Renin; Vasoconstrictor Agents | 2018 |
[Role of ACE2-Ang (1-7)-Mas receptor axis in heart failure with preserved ejection fraction with hypertension].
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Atrial Remodeling; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Heart Failure; Humans; Hypertension; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition.
Topics: Adrenocortical Carcinoma; Aldosterone; Angiotensin I; Angiotensin II; Cardiovascular Diseases; Cell Line, Tumor; Culture Media, Conditioned; Cytochrome P-450 CYP11B2; Humans; Janus Kinases; Peptide Fragments; Phosphorylation; Signal Transduction; STAT Transcription Factors | 2019 |
Effects of the selective chymase inhibitor TEI-F00806 on the intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Chymases; Hypertension; Kidney; Male; Mice; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2018 |
Effects of angiotensin-(1-7) and angiotensin II on vascular tone in human cirrhotic splanchnic vessels.
Topics: Angiotensin I; Angiotensin II; Female; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Omentum; Peptide Fragments; Renin-Angiotensin System; Vasodilation | 2018 |
Involvement of angiotensin-(1-7) in the neuroprotection of captopril against focal cerebral ischemia.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Brain; Brain Ischemia; Captopril; Male; Neuroprotection; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2018 |
Increased expression of miR-33a in monocytes from Mexican hypertensive patients in elevated carotid intima-media thickness.
Topics: Aged; Angiotensin I; Angiotensin II; Carotid Intima-Media Thickness; Case-Control Studies; Female; Humans; Hypertension; Male; MicroRNAs; Middle Aged; Monocytes; Peptide Fragments; Sterol Regulatory Element Binding Proteins | 2018 |
Obesity is Associated with Higher Blood Pressure and Higher Levels of Angiotensin II but Lower Angiotensin-(1-7) in Adolescents Born Preterm.
Topics: Adolescent; Angiotensin I; Angiotensin II; Body Mass Index; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Male; Pediatric Obesity; Peptide Fragments; Pregnancy; Premature Birth; Prospective Studies | 2019 |
BML-111, a lipoxin receptor agonist, protects against acute injury via regulating the renin angiotensin-aldosterone system.
Topics: Angiotensin I; Angiotensin II; Animals; Cytoprotection; Down-Regulation; Heptanoic Acids; Liver; Lung Injury; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Lipoxin; Renin-Angiotensin System; Up-Regulation | 2019 |
Anti-hypersensitive effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperesthesia; Male; Mice; Neuralgia; p38 Mitogen-Activated Protein Kinases; Pain Perception; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord; Vasodilator Agents | 2019 |
Effects of Resveratrol on the Renin-Angiotensin System in the Aging Kidney.
Topics: Albuminuria; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Collagen Type IV; Fibronectins; Fibrosis; Kidney; Male; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Peptide Fragments; Plant Extracts; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Renal Insufficiency, Chronic; Renin-Angiotensin System; Resveratrol; Superoxide Dismutase | 2018 |
Anti-inflammatory effects of Ang-(1-7) via TLR4-mediated inhibition of the JNK/FoxO1 pathway in lipopolysaccharide-stimulated RAW264.7 cells.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Forkhead Box Protein O1; Interleukin-6; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 4; Mice; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; RAW 264.7 Cells; Receptors, G-Protein-Coupled; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2019 |
Sacubitril/valsartan (LCZ696) significantly reduces aldosterone and increases cGMP circulating levels in a canine model of RAAS activation.
Topics: Aldosterone; Aminobutyrates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cross-Over Studies; Cyclic GMP; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Female; Heart Failure; Humans; Male; Natriuretic Peptides; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles; Valsartan | 2019 |
[Aliskiren inhibits angiotensin II/angiotensin 1-7(Ang II/Ang1-7) signal pathway in rats with diabetic nephropathy].
Topics: Amides; Angiotensin I; Angiotensin II; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fumarates; Male; Peptide Fragments; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Unique mechanistic insights into the beneficial effects of angiotensin-(1-7) on the prevention of cardiac fibrosis: A metabolomic analysis of primary cardiac fibroblasts.
Topics: Angiotensin I; Angiotensin II; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Differentiation; Cell Proliferation; Cells, Cultured; Fibroblasts; Fibrosis; Gas Chromatography-Mass Spectrometry; Glutathione; Heart Diseases; Male; Metabolome; Oxidative Stress; Peptide Fragments; Rats, Sprague-Dawley; Reactive Oxygen Species | 2019 |
Angiotensin-(1-7) induced vascular relaxation in spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Arterial Pressure; Coronary Vessels; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Nitric Oxide; Peptide Fragments; Pulmonary Artery; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, G-Protein-Coupled; Signal Transduction; Vasodilation | 2019 |
Egg White-Derived Antihypertensive Peptide IRW (Ile-Arg-Trp) Reduces Blood Pressure in Spontaneously Hypertensive Rats via the ACE2/Ang (1-7)/Mas Receptor Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Egg Proteins; Endothelium, Vascular; Male; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptors, G-Protein-Coupled; Vasodilation | 2019 |
Chronic Angiotensin 1-7 Infusion Prevents Angiotensin-II-Induced Cognitive Dysfunction and Skeletal Muscle Injury in a Mouse Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Body Weight; Cerebrovascular Circulation; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Maze Learning; Mice; Muscle, Skeletal; Peptide Fragments; Rotarod Performance Test | 2019 |
Cardioprotection Conferred by Sitagliptin Is Associated with Reduced Cardiac Angiotensin II/Angiotensin-(1-7) Balance in Experimental Chronic Kidney Disease.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Blood Pressure; Body Weight; Cardiotonic Agents; Diastole; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Kidney; Kidney Function Tests; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Renal Insufficiency, Chronic; Renin-Angiotensin System; Sitagliptin Phosphate; Up-Regulation; Ventricular Remodeling | 2019 |
Aerobic exercise training prevents obesity and insulin resistance independent of the renin angiotensin system modulation in the subcutaneous white adipose tissue.
Topics: Adipose Tissue, White; Adiposity; Angiotensin I; Angiotensin II; Animals; Biomarkers; Body Weight; Feeding Behavior; Glucose; Insulin Resistance; Male; Mice, Inbred C57BL; Obesity; Peptide Fragments; Peptides; Physical Conditioning, Animal; Renin-Angiotensin System; RNA, Messenger; Subcutaneous Fat; Thermogenesis; Uncoupling Protein 1 | 2019 |
Cardiac hypertrophy in mice submitted to a swimming protocol: influence of training volume and intensity on myocardial renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Hypertrophy, Left Ventricular; Male; Mice, Inbred BALB C; Myocardium; Peptide Fragments; Physical Conditioning, Animal; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Swimming; Ventricular Remodeling | 2019 |
Modulation of renin angiotensin system components by high glucose levels in the culture of collecting duct cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cell Line; Glucose; Kidney Tubules, Collecting; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System | 2019 |
Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracosis; Captopril; Cell Differentiation; Cell Line; Collagen; Disease Models, Animal; Female; Hedgehog Proteins; Humans; Lung; Male; Middle Aged; Myofibroblasts; Oligopeptides; Peptide Fragments; Pulmonary Fibrosis; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Silicosis | 2019 |
Protective Effect of Angiotensin (1-7) on Silicotic Fibrosis in Rats.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Cell Differentiation; Cells, Cultured; Collagen Type I; Disease Models, Animal; Lung; Myofibroblasts; Peptide Fragments; Peptidyl-Dipeptidase A; Rats, Wistar; Silicosis | 2019 |
Prehypertension exercise training attenuates hypertension and cardiac hypertrophy accompanied by temporal changes in the levels of angiotensin II and angiotensin (1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiomegaly; Diastole; Male; Myocardium; Peptide Fragments; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Prehypertension; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling | 2019 |
Intrarenal Renin-Angiotensin-System Dysregulation after Kidney Transplantation.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Enzyme Activation; Female; Gene Expression Regulation, Enzymologic; Humans; Kidney; Kidney Transplantation; Male; Middle Aged; Models, Biological; Peptide Fragments; Postoperative Complications; Renin; Renin-Angiotensin System | 2019 |
Ang-(1-7) treatment attenuates lipopolysaccharide-induced early pulmonary fibrosis.
Topics: Angiotensin I; Angiotensin II; Animals; Bronchoalveolar Lavage Fluid; Cadherins; Drug Evaluation, Preclinical; Imidazoles; Lipopolysaccharides; Lung; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Random Allocation; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Transforming Growth Factor beta; Vasodilator Agents; Vimentin | 2019 |
Interaction of N-acetyl-seryl-aspartyl-lysyl-proline with the angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cell Differentiation; Cells, Cultured; Collagen; Collagen Type I; Fibroblasts; Humans; Male; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Silicosis | 2019 |
Sex-related differences in the intratubular renin-angiotensin system in two-kidney, one-clip hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Constriction; Disease Models, Animal; Estrogens; Female; Hypertension; Hypertrophy, Left Ventricular; Kidney Tubules; Macrophages; Male; Ovariectomy; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renal Artery; Renin-Angiotensin System; Sex Factors; Signal Transduction | 2019 |
Age-related changes in the local intestinal renin-angiotensin system in normotensive and spontaneously hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Hypertension; Intestines; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System | 2019 |
AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Heat Stroke; Hepatocytes; Humans; Imidazoles; Inflammasomes; Inflammation; Interleukin-1beta; Liver; Liver Cirrhosis; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Prospective Studies; Pyroptosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
Therapeutic Delivery of Ang(1-7) via Genetically Modified Probiotic: A Dosing Study.
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Drug Administration Schedule; Lacticaseibacillus paracasei; Male; Models, Animal; Peptide Fragments; Pharmaceutical Vehicles; Probiotics; Proof of Concept Study; Rats; Rats, Inbred BN; Rats, Inbred F344; Recombinant Proteins | 2020 |
Angiotensin-(1-7) mitigated angiotensin II-induced abdominal aortic aneurysms in apolipoprotein E-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments | 2020 |
Assessment of Pregabalin-Induced Cardiotoxicity in Rats: Mechanistic Role of Angiotensin 1-7.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Cardiotoxicity; Cyclic AMP-Dependent Protein Kinases; Heart Diseases; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinase; Pregabalin; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Stroke Volume; Ventricular Function, Left | 2020 |
Significance of the angiotensin I/angiotensin II/angiotensin-(1-7) axis in the pathogenesis of systemic sclerosis.
Topics: Adult; Aged; Angiotensin I; Angiotensin II; Female; Humans; Male; Middle Aged; Peptide Fragments; Scleroderma, Systemic; Young Adult | 2020 |
Renin-Angiotensin-Aldosterone System Triple-A Analysis for the Screening of Primary Aldosteronism.
Topics: Adult; Aldosterone; Angiotensin I; Angiotensin II; Essential Hypertension; Female; Humans; Hyperaldosteronism; Male; Middle Aged; Renin-Angiotensin System; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2020 |
Effects of Angiotensin-(1-7) and Angiotensin II on Acetylcholine-Induced Vascular Relaxation in Spontaneously Hypertensive Rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Hypertension; Male; Nitric Oxide; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vasodilation | 2019 |
Tsantan Sumtang attenuated chronic hypoxia-induced right ventricular structure remodeling and fibrosis by equilibrating local ACE-AngII-AT1R/ACE2-Ang1-7-Mas axis in rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Male; Medicine, Tibetan Traditional; Peptide Fragments; Peptidyl-Dipeptidase A; Plant Preparations; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ventricular Remodeling | 2020 |
Role of Angiotensin-(1-7) via MAS receptor in human sperm motility and acrosome reaction.
Topics: Acrosome Reaction; Adult; Angiotensin I; Angiotensin II; Asthenozoospermia; Humans; Male; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Sperm Motility; Spermatozoa | 2020 |
Severe food restriction activates the central renin angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Arterial Pressure; Autoradiography; Caloric Restriction; Female; Heart Rate; Hypothalamus; Injections, Intraventricular; Losartan; Organum Vasculosum; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Preoptic Area; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Starvation; Subfornical Organ | 2020 |
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Formaldehyde; Humans; Injections, Spinal; Male; Mice; Microglia; Neurons; Nociception; p38 Mitogen-Activated Protein Kinases; Pain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord | 2020 |
High hydrostatic pressure induces atrial electrical remodeling through angiotensin upregulation mediating FAK/Src pathway activation.
Topics: Angiotensin I; Angiotensin II; Animals; Anti-Arrhythmia Agents; Atrial Appendage; Atrial Fibrillation; Atrial Remodeling; Cell Line, Tumor; Focal Adhesion Kinase 1; Humans; Hydrostatic Pressure; Mice; Myocytes, Cardiac; Peptide Fragments; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; src-Family Kinases; Up-Regulation; Valsartan | 2020 |
Angiotensin I and angiotensin II concentrations and their ratio in catecholamine-resistant vasodilatory shock.
Topics: Angiotensin I; Angiotensin II; Catecholamines; Female; Humans; Male; Shock | 2020 |
AVE0991, a nonpeptide angiotensin-(1-7) mimic, inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Disease Models, Animal; Humans; Imidazoles; Immunohistochemistry; Lipids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Molecular Mimicry; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments | 2020 |
Electroacupuncture Improved Chronic Cerebral Hypoperfusion-Induced Anxiety-Like Behavior and Memory Impairments in Spontaneously Hypertensive Rats by Downregulating the ACE/Ang II/AT1R Axis and Upregulating the ACE2/Ang-(1-7)/MasR Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anxiety; Cerebrovascular Disorders; Down-Regulation; Electroacupuncture; Hippocampus; Male; Memory Disorders; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Up-Regulation | 2020 |
Effect of sample delivery conditions on Renin-Angiotensin-Aldosterone System (RAAS) assay.
Topics: Adult; Aged; Aldosterone; Angiotensin I; Angiotensin II; Female; Healthy Volunteers; Humans; Male; Middle Aged; Radioimmunoassay; Refrigeration; Renin; Renin-Angiotensin System; Specimen Handling | 2020 |
The Role of the Renin-Angiotensin System in Severe Acute Respiratory Syndrome-CoV-2 Infection.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; COVID-19; Down-Regulation; Enzyme Induction; Female; Host-Pathogen Interactions; Humans; Hypertension; Lung; Male; Organ Specificity; Receptors, Coronavirus; Renin-Angiotensin System; Respiratory Distress Syndrome; SARS-CoV-2; Virus Internalization | 2021 |
Association of circulating uric acid and angiotensin-(1-7) in relation to higher blood pressure in adolescents and the influence of preterm birth.
Topics: Adolescent; Angiotensin I; Angiotensin II; Blood Pressure; Cross-Sectional Studies; Female; Humans; Hypertension; Infant, Newborn; Peptide Fragments; Pregnancy; Premature Birth; Renin; Renin-Angiotensin System; Uric Acid | 2020 |
Diminazene aceturate extenuate the renal deleterious consequences of angiotensin-II induced by γ-irradiation through boosting ACE2 signaling cascade.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Gamma Rays; Glutathione; Male; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Superoxide Dismutase | 2020 |
Critical Role of Neprilysin in Kidney Angiotensin Metabolism.
Topics: Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Case-Control Studies; Chymases; Enzyme Inhibitors; Female; Humans; Kidney; Male; Mice, Inbred C57BL; Middle Aged; Neprilysin; Peptide Fragments; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2020 |
Angiotensin-(1-7) receptor Mas antagonist (A779) influenced gliosis and reduced synaptic density in the spinal cord after peripheral axotomy.
Topics: Angiotensin I; Angiotensin II; Animals; Astrocytes; Axotomy; Fluorescent Antibody Technique; Gliosis; Male; Mice, Inbred C57BL; Microglia; Peptide Fragments; Receptors, G-Protein-Coupled; Spinal Cord; Synapses | 2020 |
Physiological cyclic stretch up-regulates angiotensin-converting enzyme 2 expression to reduce proliferation and migration of vascular smooth muscle cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cell Movement; Cell Proliferation; Cells, Cultured; Enzyme Induction; Humans; JNK Mitogen-Activated Protein Kinases; Mechanotransduction, Cellular; Muscle Spindles; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Peptide Fragments; Protein Kinase C beta; Transcription Factor AP-1 | 2020 |
Vascular Endothelial Growth Factor (VEGF) as a Vital Target for Brain Inflammation during the COVID-19 Outbreak.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Blood-Brain Barrier; Brain; Coronavirus Infections; COVID-19; Cytokines; Humans; Inflammation; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; SARS-CoV-2; Vascular Endothelial Growth Factor A | 2020 |
Effect of angiotensin II and angiotensin-(1-7) on proliferation of stem cells from human dental apical papilla.
Topics: Adolescent; Angiotensin I; Angiotensin II; Cell Proliferation; Cells, Cultured; Dental Papilla; Female; Humans; Imidazoles; Male; MAP Kinase Signaling System; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Stem Cells | 2021 |
Apelin-potential therapy for COVID-19?
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Apelin; Apelin Receptors; Betacoronavirus; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Drug Repositioning; Humans; Mice; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; SARS-CoV-2 | 2020 |
Alterations of the renin angiotensin system in human end-stage heart failure before and after mechanical cardiac unloading by LVAD support.
Topics: Angiotensin I; Angiotensin II; beta-Arrestins; Female; Heart Failure; Heart-Assist Devices; Humans; Male; Middle Aged; Proto-Oncogene Mas; ras Proteins; Renin-Angiotensin System; Signal Transduction | 2020 |
SARS-CoV-2 Pathogenesis: Imbalance in the Renin-Angiotensin System Favors Lung Fibrosis.
Topics: Alveolar Epithelial Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Betacoronavirus; Coronavirus Infections; COVID-19; Host Microbial Interactions; Humans; Lung; Pandemics; Peptide Fragments; Peptidyl-Dipeptidase A; Pneumonia, Viral; Pulmonary Fibrosis; Receptors, Coronavirus; Receptors, Virus; Renin-Angiotensin System; SARS-CoV-2; Transforming Growth Factor beta | 2020 |
Angiotensin-Ⅱ and angiotensin-(1-7) imbalance affects comorbidity of depression and coronary heart disease.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Case-Control Studies; China; Comorbidity; Coronary Disease; Depression; Female; Gene Expression Regulation; Genotype; Humans; Linear Models; Male; Middle Aged; Peptide Fragments; Polymorphism, Single Nucleotide; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; ROC Curve; Signal Transduction; Surveys and Questionnaires | 2020 |
Cardioprotection Generated by Aerobic Exercise Training is Not Related to the Proliferation of Cardiomyocytes and Angiotensin-(1-7) Levels in the Hearts of Rats with Supravalvar Aortic Stenosis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Stenosis, Supravalvular; Aurora Kinase B; Cell Cycle; Cell Proliferation; Chromatography, High Pressure Liquid; Cyclin D2; Echocardiography; Exercise Test; Male; Myeloid Ecotropic Viral Integration Site 1 Protein; Myocardium; Myocytes, Cardiac; Peptide Fragments; Physical Conditioning, Animal; Rats; Rats, Wistar; Renin-Angiotensin System | 2020 |
Alteration and association between serum ACE2/ angiotensin(1-7)/Mas axis and oxidative stress in chronic kidney disease: A pilot study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Angiotensin I; Angiotensin II; Case-Control Studies; Female; Humans; Male; Middle Aged; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Pilot Projects; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2020 |
Aqueous humor renin, angiotensin I, and angiotensin II activity in primary open-angle glaucoma.
Topics: Angiotensin I; Angiotensin II; Aqueous Humor; Cataract; Glaucoma, Open-Angle; Humans; Renin | 2020 |
COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Anticoagulants; Cardiovascular Diseases; COVID-19; Humans; Hypertension; Models, Theoretical; Peptide Fragments; Renin-Angiotensin System; Respiration; Risk Factors; Venous Thromboembolism; Virus Internalization | 2020 |
The possible role of a bacterial aspartate β-decarboxylase in the biosynthesis of alamandine.
Topics: Angiotensin I; Angiotensin II; Animals; Carboxy-Lyases; Humans; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2020 |
Angiotensin-converting enzyme 2 activator, DIZE in the basolateral amygdala attenuates the tachycardic response to acute stress by modulating glutamatergic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Basolateral Nuclear Complex; Diminazene; Glutamic Acid; Heart Rate; Neurons; Peptide Fragments; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tachycardia | 2020 |
The Actin Bundling Protein Fascin-1 as an ACE2-Accessory Protein.
Topics: Actins; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carrier Proteins; HEK293 Cells; Humans; Mice; Microfilament Proteins; Peptide Fragments; Proteomics | 2022 |
Localization of angiotensin-(1-7) and Mas receptor in the rat ovary throughout the estrous cycle.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Enzyme Activation; Estrous Cycle; Female; Granulosa Cells; Immunohistochemistry; Ovarian Follicle; Ovary; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; RNA, Messenger | 2020 |
Altered Serum Levels of Renin-Angiotensin System Markers in Migraine.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Biomarkers; Cross-Sectional Studies; Female; Humans; Male; Migraine Disorders; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Severity of Illness Index; Young Adult | 2020 |
Characterization of the Renin-Angiotensin System in Aged Cavernosal Tissue and its Role in Penile Fibrosis.
Topics: Aged; Angiotensin I; Angiotensin II; Animals; Fibrosis; Humans; Male; Mice; Penile Erection; Penile Induration; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System | 2020 |
Different reactive species modulate the hypotensive effect triggered by angiotensins at CVLM of 2K1C hypertensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Male; Medulla Oblongata; Peptide Fragments; Rats; Reactive Oxygen Species; Renin-Angiotensin System; Vasoconstrictor Agents | 2020 |
Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diminazene; Imidazoles; Ischemia; Kidney; Liver; Male; Myocardium; Oxidative Stress; Peptide Fragments; Peroxidase; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2020 |
N-Acetyl-Seryl-Asparyl-Lysyl-Proline regulates lung renin angiotensin system to inhibit epithelial-mesenchymal transition in silicotic mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Losartan; Lung; Male; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Silicosis | 2020 |
Angiotensinergic receptors in the medial amygdaloid nucleus differently modulate behavioral responses in the elevated plus-maze and forced swimming test in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Corticomedial Nuclear Complex; Imidazoles; Losartan; Male; Maze Learning; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Swimming | 2021 |
Activation of angiotensin II type-2 receptor protects against cigarette smoke-induced COPD.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Inflammatory Agents; Antioxidants; Cytokines; Disease Models, Animal; Female; Imidazoles; Inflammation Mediators; Lung; Macrophages, Alveolar; Mice, Inbred BALB C; Neutrophils; Oxidative Stress; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Smoke; Sulfonamides; Thiophenes; Tobacco Products | 2020 |
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2020 |
Stable Plasma Sample Storage in Acetonitrile for Angiotensin and Aldosterone Analysis.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Humans | 2021 |
Mica Can Alleviate TNBS-Induced Colitis in Mice by Reducing Angiotensin II and IL-17A and Increasing Angiotensin-Converting Enzyme 2, Angiotensin 1-7, and IL-10.
Topics: Aluminum Silicates; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Colitis; Eating; Enzyme-Linked Immunosorbent Assay; Interleukin-10; Interleukin-17; Male; Mice; Peptide Fragments; Trinitrobenzenesulfonic Acid | 2020 |
Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose.
Topics: 3T3 Cells; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Development; Glucose; Male; Mice; Osteoblasts; Osteoclasts; Osteoporosis; Peptide Fragments; Phosphorylation; Rats; Rats, Inbred SHR; RAW 264.7 Cells | 2021 |
Extended Cleavage Specificity of the Rat Vascular Chymase, a Potential Blood Pressure Regulating Enzyme Expressed by Rat Vascular Smooth Muscle Cells.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Cell Lineage; Chemokine CCL2; Chymases; HEK293 Cells; Humans; Mast Cells; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptide Library; Phylogeny; Rats; Recombinant Proteins | 2020 |
Human Angiotensin-Converting Enzyme may be under malaria selection pressure: a need to explore.
Topics: Angiotensin I; Angiotensin II; Humans; INDEL Mutation; Malaria; Molecular Epidemiology; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Renin-Angiotensin System | 2021 |
Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1-7) and Angiotensin II in Human Plasma.
Topics: Angiotensin I; Angiotensin II; Chromatography, Agarose; COVID-19; Enzyme-Linked Immunosorbent Assay; Humans; Peptide Fragments; Radioimmunoassay; Reference Standards; Renin-Angiotensin System; SARS-CoV-2; Sensitivity and Specificity; Specimen Handling | 2021 |
Metabolism of angiotensin peptides by angiotensin converting enzyme 2 (ACE2) and analysis of the effect of excess zinc on ACE2 enzymatic activity.
Topics: Aminopeptidases; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Humans; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Recombinant Proteins; Renin-Angiotensin System; Zinc | 2021 |
ACE2 abrogates tumor resistance to VEGFR inhibitors suggesting angiotensin-(1-7) as a therapy for clear cell renal cell carcinoma.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Vascular Endothelial Growth Factor A | 2021 |
Renin-angiotensin-aldosterone system peptide profiles in patients with COVID-19.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Case-Control Studies; COVID-19; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptidyl-Dipeptidase A; Prospective Studies; Renin; Renin-Angiotensin System; SARS-CoV-2 | 2021 |
Localization of angiotensin II type 1 receptor gene expression in rodent and human kidneys.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Gene Expression; Humans; Kidney; Mice; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin-Angiotensin System; Rodentia | 2021 |
Renin-angiotensin system dysregulation in critically ill patients with acute respiratory distress syndrome due to COVID-19: a preliminary report.
Topics: Aged; Aged, 80 and over; Angiotensin I; Angiotensin II; COVID-19; Critical Illness; Female; Humans; Male; Middle Aged; Renin; Renin-Angiotensin System; Respiratory Distress Syndrome | 2021 |
Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex.
Topics: Adrenal Cortex; Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Cytochrome P-450 CYP11B2; Humans; Hydrocortisone; Peptide Fragments; Proto-Oncogene Mas | 2021 |
Strengthening CoViD-19 therapy via combinations of RAS modulators.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19 Drug Treatment; Humans; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2021 |
Revisiting the renin-angiotensin system.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensinogen; Animals; Blood Pressure; Chymases; Diabetic Nephropathies; Gene Expression Regulation; Humans; Hypertension; Kidney; Peptide Fragments; Renin-Angiotensin System; Signal Transduction; Water-Electrolyte Balance | 2021 |
Myocardial Angiotensin Metabolism in End-Stage Heart Failure.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Disease Progression; Female; Heart Failure; Heart Transplantation; Humans; Male; Mass Spectrometry; Middle Aged; Myocardium; Peptide Fragments; Renin-Angiotensin System; Stroke Volume | 2021 |
His345 mutant of angiotensin-converting enzyme 2 (ACE2) remains enzymatically active against angiotensin II.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Peptide Hormones; Peptidyl-Dipeptidase A | 2021 |
Expression of ACE2, Soluble ACE2, Angiotensin I, Angiotensin II and Angiotensin-(1-7) Is Modulated in COVID-19 Patients.
Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Female; Gene Expression Profiling; HLA-DR Antigens; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes; Peptide Fragments; Pilot Projects; Prospective Studies; RNA, Messenger; Virus Shedding | 2021 |
Another controller system for arterial pressure. AngII-vasopressin neural network of the parvocellular paraventricular nucleus may regulate arterial pressure during hypotension.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Hemorrhage; Hypotension; Hypovolemia; Male; Nerve Net; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Vasopressins | 2021 |
Scorpion bradykinin potentiating factor mitigates lung damage induced by γ-irradiation in rats: Insights on AngII/ACE/Ang(1-7) axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Gamma Rays; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Scorpions | 2021 |
Local Renin-Angiotensin System Signaling Mediates Cellular Function of Aortic Valves.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve; Cells, Cultured; Fluorescent Antibody Technique; Losartan; Myofibroblasts; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Swine; Tetrahydroisoquinolines | 2021 |
Sex differences in the lung ACE/ACE2 balance in hypertensive rats.
Topics: ADAM17 Protein; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Down-Regulation; Female; Lung; Male; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Wistar; RNA, Messenger; Sex Characteristics | 2021 |
Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries.
Topics: ADAM17 Protein; Aged; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; COVID-19; Enzyme Activation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peptide Fragments; Prognosis; Prospective Studies; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Renin-Angiotensin System; Respiration, Artificial; Risk; SARS-CoV-2; Treatment Outcome | 2022 |
Angiotensin (ang) 1-7 inhibits ang II-induced atrial fibrosis through regulating the interaction of proto-oncogene tyrosine-protein kinase Src (c-Src) and Src homology region 2 domain-containing phosphatase-1 (SHP-1)).
Topics: Angiotensin I; Angiotensin II; Animals; Fibrosis; Matrix Metalloproteinase 2; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fyn; Rats; Rats, Sprague-Dawley; Signal Transduction; src Homology Domains; Transforming Growth Factor beta | 2021 |
Immunoneutralization of human angiotensin-(1-12) with a monoclonal antibody in a humanized model of hypertension.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Antibodies, Monoclonal; Blood Pressure; Female; Humans; Hypertension; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley | 2022 |
The Effects of Angiotensin II or Angiotensin 1-7 on Rat Pial Microcirculation during Hypoperfusion and Reperfusion Injury: Role of Redox Stress.
Topics: Angiotensin I; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Female; Male; Microcirculation; Microscopy, Fluorescence; Peptide Fragments; Pia Mater; Proto-Oncogene Mas; Rats; Reactive Oxygen Species; Reperfusion Injury; Tetrazoles | 2021 |
Angiotensin Type 2 and Mas Receptor Activation Prevents Myocardial Fibrosis and Hypertrophy through the Reduction of Inflammatory Cell Infiltration and Local Sympathetic Activity in Angiotensin II-Dependent Hypertension.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Disease Models, Animal; Fibrosis; Hypertension; Imidazoles; Injections, Intraperitoneal; Losartan; Male; Peptide Fragments; Proto-Oncogene Mas; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiophenes; Tyrosine 3-Monooxygenase | 2021 |
Renin-angiotensin system blockade on angiotensin-converting enzyme 2 and TMPRSS2 in human type II pneumocytes.
Topics: Adult; Age Factors; Aged; Alveolar Epithelial Cells; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Lung; Male; Middle Aged; Peptide Fragments; Renin-Angiotensin System; Retrospective Studies; Serine Endopeptidases; Smoking | 2022 |
Angiotensin-(1-7), a protective peptide against vascular aging.
Topics: Aged; Aging; Angiotensin I; Angiotensin II; Frailty; Humans; Peptide Fragments; Renin-Angiotensin System | 2022 |
Exercise training improves cardiovascular control in sinoaortic denervated SHR by reducing the elevated angiotensin II and augmenting angiotensin-(1-7) availability within autonomic and neuroendocrine PVN nuclei.
Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Hypertension; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred SHR | 2022 |
Angiotensin-(1-7) promotes mitochondrial translocation of human telomerase reverse transcriptase in HUVECs through the TOM20 complex.
Topics: Angiotensin I; Angiotensin II; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Mitochondrial Precursor Protein Import Complex Proteins; Mitochondrial Proteins; Peptide Fragments; Telomerase | 2022 |
Chicken Muscle-Derived ACE2 Upregulating Peptide VVHPKESF Inhibits Angiotensin II-Stimulated Inflammation in Vascular Smooth Muscle Cells
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Chickens; Inflammation; Muscle, Smooth, Vascular; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Receptors, G-Protein-Coupled | 2022 |
Angiotensin 1-7 mitigates rhabdomyolysis induced renal injury in rats via modulation of TLR-4/NF-kB/iNOS and Nrf-2/heme‑oxygenase-1 signaling pathways.
Topics: Angiotensin I; Angiotensin II; Animals; Heme; Kidney; Male; NF-kappa B; Nitric Oxide Synthase Type II; Peptide Fragments; Rats; Receptors, G-Protein-Coupled; Rhabdomyolysis; Signal Transduction; Toll-Like Receptor 4 | 2022 |
Renin-Angiotensin System in Huntington's Disease: Evidence from Animal Models and Human Patients.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Disease Models, Animal; Humans; Huntington Disease; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2022 |
Angiotensin (1-7) Delivered Orally via Probiotic in Combination With Exercise: Sex-Dependent Influence on Health Span.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Peptide Fragments; Quality of Life; Rats; Renin-Angiotensin System | 2023 |
Functional Significance of Angiotensin Receptor Type 2 in the Neuroplasticity of Autonomic Ganglia in (mRen2)27 Transgenic Hypertensive Rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Ganglia, Autonomic; Humans; Hypertension; NADPH Oxidase 4; Neuronal Plasticity; Rats; Rats, Transgenic; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin; RNA, Messenger | 2023 |
Activation of Angiotensin-converting Enzyme 2 Protects Against Lipopolysaccharide-induced Glial Activation by Modulating Angiotensin-converting Enzyme 2/Angiotensin (1-7)/Mas Receptor Axis.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents; Lipopolysaccharides; Male; Neuroglia; Neuroinflammatory Diseases; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled | 2023 |
Changes of ACE2 in different glucose metabolites and its relationship with COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; C-Reactive Protein; COVID-19; Diabetes Mellitus, Type 2; Glucose; Humans; Interleukin-6; Peptide Fragments; Prediabetic State | 2022 |
Influence of sex on renin-angiotensin-aldosterone system metabolites and enzymes in Doberman Pinschers.
Topics: Aldosterone; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; Female; Male; Renin-Angiotensin System | 2023 |
The systemic renin-angiotensin system in COVID-19.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antihypertensive Agents; COVID-19; Humans; Peptide Hormones; Renin; Renin-Angiotensin System; SARS-CoV-2 | 2022 |
Attenuation of Smooth Muscle Cell Phenotypic Switching by Angiotensin 1-7 Protects against Thoracic Aortic Aneurysm.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Thoracic; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myocytes, Smooth Muscle; Phenotype | 2022 |
ACE2/ANG-(1-7)/Mas receptor axis activation prevents inflammation and improves cognitive functions in streptozotocin induced rat model of Alzheimer's disease-like phenotypes.
Topics: Acetylcholine; Alzheimer Disease; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cognition; Inflammation; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Rats; Reactive Oxygen Species; Receptors, G-Protein-Coupled; Streptozocin | 2023 |
Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7).
Topics: Aging; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Claudin-1; Dysbiosis; Gastrointestinal Microbiome; Male; Mice; Occludin; Peptide Fragments; Peptidyl-Dipeptidase A | 2023 |
Angiotensin-Converting Enzyme 2 Activation Is Not a Common Feature of Angiotensin-Converting Enzyme Inhibitory Peptides.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Molecular Docking Simulation; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR | 2023 |
Identification and Screening of Potential ACE2 Activating Peptides from Soybean Protein Isolate Hydrolysate against Ang II-Induced Endothelial Dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Glycine max; Human Umbilical Vein Endothelial Cells; Humans; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Soybean Proteins; Vascular Diseases | 2023 |
Effects of Angiotensin 1-7 and Mas Receptor Agonist on Renal System in a Rat Model of Heart Failure.
Topics: Angiotensin I; Angiotensin II; Animals; Cardiomegaly; Heart Failure; Kidney; Peptide Fragments; Rats; Renin-Angiotensin System | 2023 |
Targeting the renin angiotensin system for respiratory diseases.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Fibrosis; Humans; Peptide Fragments; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Respiratory Tract Diseases; Signal Transduction | 2023 |
G-protein-coupled receptor MAS deletion produces a preeclampsia-like phenotype in FVB/N mice.
Topics: Angiotensin I; Angiotensin II; Animals; Female; Humans; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Phenotype; Placenta; Pre-Eclampsia; Pregnancy; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System | 2023 |
Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Female; Humans; Hypertension; Lacticaseibacillus paracasei; Male; Peptidyl-Dipeptidase A; Rats | 2023 |