angiotensin ii has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 33 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (6.06) | 18.2507 |
2000's | 22 (66.67) | 29.6817 |
2010's | 8 (24.24) | 24.3611 |
2020's | 1 (3.03) | 2.80 |
Authors | Studies |
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Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
Saward, L; Zahradka, P | 1 |
Nakamura, M; Seki, T; Sperelakis, N; Sunagawa, M; Yokoshiki, H | 1 |
Govindarajan, G; Lucchesi, PA; Rocic, P; Sabri, A | 1 |
Brautigan, D; Everett, AD; Nairn, AC; Stoops, TD | 1 |
Kirima, K; Kyaw, M; Suzaki, Y; Tamaki, T; Tsuchiya, K; Yoshizumi, M | 1 |
Freeman, EJ; Silfani, TN | 1 |
Balla, T; Baukal, AJ; Bor, M; Catt, KJ; Gaborik, Z; Hunyady, L; Lodge, R; Olivares-Reyes, JA; Szaszak, M | 1 |
Griendling, KK; Rocic, P; Seshiah, PN; Taniyama, Y; Valppu, L; Weber, DS | 1 |
Li, N; Wang, HJ; Wang, XY; Wu, KG; Xie, LD; Xu, CS | 1 |
Chester, AH; Hafizi, S; Proud, CG; Wang, X; Yacoub, MH | 1 |
Kolachana, P; Lawsin, LM; Moore, J; Perlman, A; Ringel, MD; Saji, M | 1 |
Marsigliante, S; Muscella, A; Storelli, C | 1 |
Caruso-Neves, C; Guggino, WB; Kwon, SH | 1 |
Abdallah, Y; Helmig, S; Piper, HM; Schäfer, C; Schlüter, KD; Wenzel, S | 1 |
Marsigliante, S; Muscella, A; Romano, S; Storelli, C | 1 |
Ahmed, RA; Cao, WM; Imachi, H; Ishida, T; Kosaka, H; Li, J; Matsumoto, K; Murao, K; Nishiuchi, T; Unterman, TG; Wong, NC; Yu, X | 1 |
Bae, YS; Catt, KJ; Choi, H; Hunyady, L; Leto, TL; Rhee, SG | 1 |
Caporali, A; Cristofaro, B; Emanueli, C; Graiani, G; Madeddu, P; Meloni, M; Newby, AC; Pani, E; Sala-Newby, GB | 1 |
Baumgarten, CM; Browe, DM; Raucci, FJ; Ren, Z | 1 |
Albert, AP; Large, WA; Saleh, SN | 1 |
Catt, KJ; Chen, H; Li, B; Yin, X | 1 |
González, I; Jiménez, E; Montiel, M; Pérez de la Blanca, E; Salas, J; Urso, L | 1 |
Fujikake, T; Fujioka, K; Hanamoto, T; Ikeda, T; Ishizuka, T; Kajita, K; Mori, I; Morita, H; Nagano, I; Okada, H; Takahashi, Y; Uno, Y; Zhiliang, W | 1 |
Cai, L; Chen, X; Fu, S; Sui, G; Yang, Y; Zhao, Y | 1 |
Castillo, C; Castillo, EF; López, RM; Pérez, T | 1 |
Ge, J; Guo, L; Modgil, A; O'Rourke, ST; Pingili, A; Singh, N; Sun, C; Xuan, C; Yao, F; Zhang, Q | 1 |
Chou, CH; Chuang, LY; Guh, JY; Lu, CY | 1 |
Lin, YQ; Luo, NS; Mai, J; Qiu, Q; Wang, JF; Wen, ZZ; YangXin, C; Zhang, HF | 1 |
Agrawal, N; Gandhi, H; Naik, P; Yadav, M | 1 |
Ha, TS; Min, SY; Park, HY; Seong, SB | 1 |
Cao, J; Chen, L; Cui, X; Fan, Y; Fu, M; Ge, J; Han, X; Hu, K; Song, Y; Sun, A; Wang, J; Wang, Y; Zhou, J | 1 |
Chen, Y; Du, J; Jia, LX; Jia, MZ; Liu, X; Lu, WW; Ni, XQ; Ning, ZP; Qi, YF; Ren, JL; Tang, CS; Yu, YR; Zhang, LS; Zhang, YR; Zhu, Q | 1 |
33 other study(ies) available for angiotensin ii and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
Article | Year |
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Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Angiotensin II activates phosphatidylinositol 3-kinase in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Morpholines; Muscle, Smooth, Vascular; Phosphotransferases (Alcohol Group Acceptor); Plasminogen; Signal Transduction; Swine; Vasoconstrictor Agents | 1997 |
Angiotensin II stimulation of Ca2+-channel current in vascular smooth muscle cells is inhibited by lavendustin-A and LY-294002.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II; Animals; Aorta; Calcium Channels; Cell Line; Chromones; Electric Conductivity; Enzyme Inhibitors; Kinetics; Morpholines; Phenols; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats | 1999 |
A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Calcium; Cells, Cultured; Chromones; Crk-Associated Substrate Protein; Enzyme Inhibitors; Focal Adhesion Kinase 2; GRB2 Adaptor Protein; Hypertrophy; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Retinoblastoma-Like Protein p130; Ribosomal Protein S6 Kinases; Signal Transduction; src-Family Kinases | 2001 |
Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes.
Topics: Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Mitogen-Activated Protein Kinases; Morpholines; Myocardium; Peptide Elongation Factor 2; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sirolimus | 2001 |
Quercetin inhibits Shc- and phosphatidylinositol 3-kinase-mediated c-Jun N-terminal kinase activation by angiotensin II in cultured rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Chromones; Collagen; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Leucine; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quercetin; Rats; Rats, Sprague-Dawley; src Homology Domains; Time Factors; Tritium; Tyrosine | 2001 |
Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Blotting, Western; Cells, Cultured; Chromones; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Male; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Rats; Rats, Sprague-Dawley | 2002 |
Differential PI 3-kinase dependence of early and late phases of recycling of the internalized AT1 angiotensin receptor.
Topics: Androstadienes; Angiotensin II; Biomarkers; Cell Line; Cells, Cultured; Chromones; Clathrin-Coated Vesicles; Cytoplasmic Vesicles; Endocytosis; Endosomes; Humans; Morpholines; Phosphatidylinositol 3-Kinases; rab4 GTP-Binding Proteins; rab5 GTP-Binding Proteins; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Recombinant Fusion Proteins; Transferrin; Wortmannin | 2002 |
Angiotensin II stimulation of NAD(P)H oxidase activity: upstream mediators.
Topics: Androstadienes; Angiotensin II; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; ErbB Receptors; Flow Cytometry; Hydrogen Peroxide; Indoles; Male; Maleimides; Morpholines; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Pyrazoles; Pyrimidines; rac GTP-Binding Proteins; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; src-Family Kinases; Time Factors; Wortmannin | 2002 |
Angiotensin II stimulates phosphorylation of 4E-binding protein 1 and p70 S6 kinase in cultured vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Carrier Proteins; Cells, Cultured; Chromones; Intracellular Signaling Peptides and Proteins; Losartan; Morpholines; Muscle, Smooth, Vascular; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction | 2004 |
ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Angiotensin II; Carrier Proteins; Cell Cycle Proteins; Cells, Cultured; Chromones; Coronary Vessels; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Humans; Immunosuppressive Agents; Morpholines; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.
Topics: Angiotensin II; Animals; Butadienes; Cell Line; Chromones; Dose-Response Relationship, Drug; Drug Combinations; Enzyme Inhibitors; Epidermal Growth Factor; Glomerular Mesangium; Immunoblotting; Losartan; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Tyrphostins | 2004 |
Atypical PKC-zeta and PKC-iota mediate opposing effects on MCF-7 Na+/K+ATPase activity.
Topics: Androstadienes; Angiotensin II; Animals; Blotting, Western; Breast Neoplasms; Cattle; Cell Line, Tumor; Chromones; Culture Media, Serum-Free; Cytochalasin D; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Indoles; Isoenzymes; Kinetics; Maleimides; Morpholines; Oligodeoxyribonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Wortmannin | 2005 |
Albumin endocytosis in proximal tubule cells is modulated by angiotensin II through an AT2 receptor-mediated protein kinase B activation.
Topics: Albumins; Androstadienes; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Fractionation; Cell Line; Chromones; Endocytosis; Imidazoles; Kidney Tubules, Proximal; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 2; Staurosporine; Sus scrofa; Wortmannin | 2005 |
Contribution of PI 3-kinase isoforms to angiotensin II- and alpha-adrenoceptor-mediated signalling pathways in cardiomyocytes.
Topics: Angiotensin II; Animals; Cardiomegaly; Cells, Cultured; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Isoenzymes; Male; Microscopy, Fluorescence; Morpholines; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Receptors, Adrenergic, alpha; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases; Signal Transduction; Transforming Growth Factor beta | 2006 |
Angiotensin II does not stimulate proliferation of rat thyroid PC Cl3 cell line.
Topics: Angiotensin II; Animals; Cell Line; Cell Proliferation; Chromones; Cyclin-Dependent Kinase Inhibitor p27; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Indoles; Insulin; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-fos; Rats; RNA Interference; Signal Transduction; Thyroid Gland | 2006 |
Regulation of scavenger receptor class BI gene expression by angiotensin II in vascular endothelial cells.
Topics: Androstadienes; Angiotensin II; Cells, Cultured; Chromones; Down-Regulation; Endothelium, Vascular; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Imidazoles; Morpholines; Nitric Oxide Synthase; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Promoter Regions, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Scavenger Receptors, Class B; Tetrazoles; Wortmannin | 2007 |
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Androstadienes; Angiotensin II; Animals; Cell Line; CHO Cells; Chromones; Cricetinae; Cricetulus; Gene Expression; Humans; Indoles; Maleimides; Membrane Glycoproteins; Morpholines; Mutation; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Protein Kinase C; Pyrazoles; Pyrimidines; Quinazolines; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Superoxides; Tyrphostins; Wortmannin | 2008 |
Identification of the prosurvival activity of nerve growth factor on cardiac myocytes.
Topics: Angiotensin II; Animals; Apoptosis; Carbazoles; Cell Survival; Cells, Cultured; Chromones; Enzyme Inhibitors; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Indole Alkaloids; Morpholines; Myocytes, Cardiac; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; PC12 Cells; Phosphorylation; Rats; Receptor, trkA; Signal Transduction; Transfection | 2008 |
Regulation of swelling-activated Cl(-) current by angiotensin II signalling and NADPH oxidase in rabbit ventricle.
Topics: Angiotensin II; Animals; Cell Size; Chloride Channels; Chromones; ErbB Receptors; Heart Ventricles; Morpholines; Myocytes, Cardiac; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Protein Kinase C; Rabbits; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Signal Transduction; src-Family Kinases | 2008 |
Inhibition of native TRPC6 channel activity by phosphatidylinositol 4,5-bisphosphate in mesenteric artery myocytes.
Topics: Androstadienes; Angiotensin II; Animals; Antibodies; Cells, Cultured; Chromones; Diglycerides; Electrophysiology; Mesenteric Arteries; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 4,5-Diphosphate; Rabbits; TRPC Cation Channels; Vasoconstrictor Agents; Wortmannin | 2008 |
Differential signaling pathways in angiotensin II- and epidermal growth factor-stimulated hepatic C9 cells.
Topics: Androstadienes; Angiotensin II; Base Sequence; Calcium; Cell Line; Cholesterol; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epidermal Growth Factor; Filipin; Humans; Liver; Morpholines; Nystatin; Phosphorylation; RNA, Small Interfering; Signal Transduction; Wortmannin | 2008 |
Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells.
Topics: Androstadienes; Angiotensin II; Anthracenes; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Kinase 1; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Morpholines; Oligonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Umbilical Veins; Wortmannin | 2009 |
Effects of phorbol ester-sensitive PKC (c/nPKC) activation on the production of adiponectin in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Angiotensin II; Animals; Benzimidazoles; Biphenyl Compounds; Carbazoles; Chromones; Enzyme Activation; Gene Expression; Glucose; Insulin; Mice; Morpholines; NF-kappa B; PPAR gamma; Protein Kinase C; Tetradecanoylphorbol Acetate; Tetrazoles; Tumor Necrosis Factor-alpha | 2009 |
Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Imidazoles; Losartan; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction; Vasoconstrictor Agents | 2010 |
Effects induced by inhibitors of the phosphatidylinositol 3-kinase/Akt and nitric oxide synthase/guanylyl cyclase pathways on the isometric contraction in rat aorta: a comparative study.
Topics: Androstadienes; Angiotensin II; Animals; Aorta, Thoracic; Chromones; Endothelium, Vascular; Guanylate Cyclase; Isometric Contraction; Male; Morpholines; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxadiazoles; Phenylephrine; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Potassium; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Wortmannin | 2011 |
Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons.
Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Cells, Cultured; Chromones; Enzyme Inhibitors; Heart Rate; Hypothalamus; Male; Morpholines; Neurons; Peptide Fragments; PTEN Phosphohydrolase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vanadium Compounds | 2012 |
Interaction between TGF-β and ACE2-Ang-(1-7)-Mas pathway in high glucose-cultured NRK-52E cells.
Topics: Amino Acid Sequence; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Benzamides; Cells, Cultured; Chromones; Dioxoles; Fibronectins; Gene Expression Regulation; Glucose; Janus Kinase 2; LLC-PK1 Cells; Molecular Sequence Data; Morpholines; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptor, Transforming Growth Factor-beta Type I; Receptors, G-Protein-Coupled; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Swine; Transcription, Genetic; Transforming Growth Factor beta; Tyrphostins | 2013 |
Angiotensin II-derived reactive oxygen species promote angiogenesis in human late endothelial progenitor cells through heme oxygenase-1 via ERK1/2 and AKT/PI3K pathways.
Topics: Angiotensin II; Antioxidants; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Endothelial Progenitor Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Heme Oxygenase-1; Humans; Morpholines; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering | 2014 |
Protective effects of MCR-1329, a dual α1 and angII receptor antagonist, in mineralocorticoid-induced hypertension.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Chromones; Desoxycorticosterone Acetate; Endothelium, Vascular; Hypertension; Losartan; Male; Mineralocorticoids; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Prazosin; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptors, Angiotensin; Signal Transduction; Vasoconstriction | 2016 |
CD2-associated protein/phosphoinositide 3-kinase signaling has a preventive role in angiotensin II-induced podocyte apoptosis.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Apoptosis; Chromones; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Gene Knockdown Techniques; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Podocytes; Protein Transport; Receptor, Angiotensin, Type 1; Signal Transduction | 2016 |
Angiotensin II induces apoptosis of cardiac microvascular endothelial cells via regulating PTP1B/PI3K/Akt pathway.
Topics: Angiotensin II; Animals; Apoptosis; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Male; Morpholines; Myocardium; Phosphatidylinositol 3-Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction | 2019 |
Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway.
Topics: ADAM10 Protein; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Calcium Chloride; Cell Movement; Chromones; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; Mice, Transgenic; Morpholines; Neuropeptides; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Hormones; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Notch1; Transcription Factor HES-1 | 2021 |