angiotensin ii, sar(1)-me-tyr(4)- and angiotensin ii

angiotensin ii, sar(1)-me-tyr(4)- has been researched along with angiotensin ii in 21 studies

Compound Research Comparison

Studies (angiotensin ii, sar(1)-me-tyr(4)-)	Trials (angiotensin ii, sar(1)-me-tyr(4)-)	Recent Studies (post-2010) (angiotensin ii, sar(1)-me-tyr(4)-)	Studies (angiotensin ii)	Trials (angiotensin ii)	Recent Studies (post-2010) (angiotensin ii)
25	0	0	38,152	1,089	7,413
6	0	0	38,152	1,089	7,413

Protein Interaction Comparison

Protein	Taxonomy	angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.002
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.002
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0018
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0055
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.004
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0011

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (33.33)	18.7374
1990's	9 (42.86)	18.2507
2000's	5 (23.81)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Entzeroth, M; Mauz, AB; Van Meel, JC; Wienen, W	1
Moore, GJ; Sharma, RK; Smith, JR	1
Cordopatis, P; Franklin, KJ; Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, GJ	1
Criscione, L; de Gasparo, M; Kamber, B; Thomann, H; Whitebread, S	1
Belte, U; Cordopatis, P; Franklin, KJ; Ganter, RC; Goghari, MH; Matsoukas, J; Moore, GJ	1
Koziarz, P; Moore, GJ	1
Bovy, PR; McMahon, EG; Palomo, M; Trapani, AJ	1
Moore, GJ; Scanlon, MN	1
Franklin, KJ; Goghari, MH; Moore, GJ	1
Franklin, KJ; Moore, GJ; Nystrom, DM	1
Franklin, KJ; Matsoukas, JM; Moore, GJ; Scanlon, MN	1
Agelis, G; Ganter, R; Hondrelis, J; Matsoukas, JM; Moore, D; Moore, GJ; Smith, JR; Wu, Q; Yamdagni, R	1
Georgiev, VP; Tchekalarova, JD	1
Georgiev, V; Tchekalarova, J	1
Georgiev, V; Georgieva, D	1
Kolocouris, A; Matsoukas, J; Mavromoustakos, T; Roumelioti, P; Weisemann, R; Zervou, M	1
Alexopoulos, K; Kolocouris, A; Matsoukas, JM; Mavromoustakos, T; Moore, GJ; Roumelioti, P; Tselios, T	1
Alova, L; Georgiev, V; Stancheva, S	1
Georgiev, V; Kambourova, T; Matsoukas, J; Pechlivanova, D; Tchekalarova, J	1
Alova, L; Georgiev, V; Stancheva, S; Velkova, M	1
Benetis, NP; Giatas, N; Grdadolnik, SG; Kolocouris, A; Kyrikou, I; Matsoukas, J; Mavromoustakos, T; Minakakis, PM; Polevaya, L; Roumelioti, P; Vlahakos, D; Zervou, M; Zoga, A; Zoumpoulakis, P	1

Reviews

1 review(s) available for angiotensin ii, sar(1)-me-tyr(4)- and angiotensin ii

Article	Year
Conformation and bioactivity. Design and discovery of novel antihypertensive drugs. Current topics in medicinal chemistry, 2004, Volume: 4, Issue:4 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Design; Humans; Hypertension; Losartan; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Mimicry; Peptides; Structure-Activity Relationship	2004

Article

Year

Conformation and bioactivity. Design and discovery of novel antihypertensive drugs.

Current topics in medicinal chemistry, 2004, Volume: 4, Issue:4

Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Design; Humans; Hypertension; Losartan; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Mimicry; Peptides; Structure-Activity Relationship

2004

Other Studies

20 other study(ies) available for angiotensin ii, sar(1)-me-tyr(4)- and angiotensin ii

Article	Year
Different types of receptor interaction of peptide and nonpeptide angiotensin II antagonists revealed by receptor binding and functional studies. Molecular pharmacology, 1992, Volume: 41, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Binding Sites; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Kinetics; Losartan; Male; Muscle Contraction; Peptides; Rabbits; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles	1992
Inhibition of bovine brain calmodulin-dependent cGMP phosphodiesterase by peptide and non-peptide angiotensin receptor ligands. Biochemical and biophysical research communications, 1991, Aug-30, Volume: 179, Issue:1 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Brain; Cattle; Cell Membrane; Cyclic Nucleotide Phosphodiesterases, Type 1; Female; Kinetics; Molecular Structure; Phosphoric Diester Hydrolases; Rats; Receptors, Angiotensin; Uterus	1991
Synthesis and biological activities of angiotensin II and Sarmesin analogues containing cyclohexylalanine. International journal of peptide and protein research, 1991, Volume: 37, Issue:1 Topics: Angiotensin II; Animals; Female; In Vitro Techniques; Phenylalanine; Rats; Structure-Activity Relationship; Uterine Contraction	1991
Sarmesin is a partial agonist of angiotensin-II receptors in rabbit, but not in rat, aortic rings. Biochemical and biophysical research communications, 1990, Jun-15, Volume: 169, Issue:2 Topics: Angiotensin II; Animals; Aorta; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Rabbits; Rats; Receptors, Angiotensin; Species Specificity	1990
Importance of the N-terminal domain of the type II angiotensin antagonist sarmesin for receptor blockade. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Biological Assay; Chemical Phenomena; Chemistry; Female; Isoleucine; Methylation; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Sarcosine; Structure-Activity Relationship; Uterus	1988
On the mechanism of action of sarmesin and sarilesin at angiotensin receptors in smooth muscle. Proceedings of the Western Pharmacology Society, 1989, Volume: 32 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Female; In Vitro Techniques; Muscle, Smooth; Rats; Rats, Inbred Strains; Receptors, Angiotensin	1989
A carboxy-terminus truncated analogue of angiotensin II, [Sar1]angiotensin II-(1-7)-amide, provides an entry to a new class of angiotensin II antagonists. Journal of medicinal chemistry, 1989, Volume: 32, Issue:3 Topics: Angiotensin II; Animals; Blood Pressure; In Vitro Techniques; Peptide Fragments; Rabbits; Rats; Saralasin; Structure-Activity Relationship; Vasoconstriction	1989
Classification of angiotensin receptors in rat isolated uterus, portal vein, and aorta with the novel competitive antagonist sarmesin. Pharmacology, 1988, Volume: 37, Issue:3 Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Female; Heart Rate; In Vitro Techniques; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Portal Vein; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Uterus	1988
Structure-activity relationships for the competitive angiotensin antagonist [sarcosine,O-methyltyrosine4]angiotensin II (sarmesin). Journal of medicinal chemistry, 1986, Volume: 29, Issue:6 Topics: Angiotensin II; Animals; Female; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1986
Structure dependence of angiotensin tachyphylaxis and the mechanisms of saralasin like and sarmesin like antagonism. Proceedings of the Western Pharmacology Society, 1985, Volume: 28 Topics: Angiotensin II; Animals; Female; Rats; Saralasin; Structure-Activity Relationship; Tachyphylaxis	1985
A new approach to angiotensin antagonists: methylation of the tyrosine hydroxyl in angiotensin II. Life sciences, 1984, Jan-23, Volume: 34, Issue:4 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Blood Pressure; Female; In Vitro Techniques; Rats; Rats, Inbred Strains; Uterine Contraction	1984
Synthesis and biological activities of angiotensin II, Sarilesin, and Sarmesin analogues containing Aze or Pip at position 7. Journal of medicinal chemistry, 1993, Apr-02, Volume: 36, Issue:7 Topics: Angiotensin II; Animals; Azetidinecarboxylic Acid; Chromatography, High Pressure Liquid; Female; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Structure-Activity Relationship; Uterus	1993
Interaction of angiotensin II and adenosine receptors in pentylenetetrazol-induced kindling in mice. Brain research, 1998, Jan-01, Volume: 779, Issue:1-2 Topics: Analysis of Variance; Angiotensin II; Animals; Convulsants; Epilepsy, Tonic-Clonic; Kindling, Neurologic; Male; Mice; Mice, Inbred ICR; Pentylenetetrazole; Reaction Time; Receptors, Purinergic P1	1998
Further evidence for interaction between angiotensin II and dopamine receptors (experiments on apomorphine stereotypy). Methods and findings in experimental and clinical pharmacology, 1998, Volume: 20, Issue:5 Topics: Angiotensin II; Animals; Apomorphine; Losartan; Male; Rats; Rats, Wistar; Receptors, Dopamine; Stereotyped Behavior	1998
The role of angiotensin II and of its receptor subtypes in the acetic acid-induced abdominal constriction test. Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:2 Topics: Acetic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Colic; Imidazoles; Losartan; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Pyridines; Receptors, Angiotensin; Saralasin	1999
An effort to understand the molecular basis of hypertension through the study of conformational analysis of losartan and sarmesin using a combination of nuclear magnetic resonance spectroscopy and theoretical calculations. Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Hypertension; Losartan; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Monte Carlo Method; Protein Conformation	1999
Structural comparison between type I and type II antagonists: possible implications in the drug design of AT1 antagonists. Bioorganic & medicinal chemistry letters, 2000, Apr-17, Volume: 10, Issue:8 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Drug Design; Female; Magnetic Resonance Spectroscopy; Models, Molecular; Rats; Receptors, Angiotensin; Structure-Activity Relationship; Uterus	2000
The effects of peptide and nonpeptide angiotensin II-receptor ligands on the activity of brain monoamine oxidase in water-repleted rats. Acta physiologica et pharmacologica Bulgarica, 2000, Volume: 25, Issue:2 Topics: Angiotensin II; Animals; Body Water; Brain; Drinking; Imidazoles; Isoenzymes; Ligands; Losartan; Male; Monoamine Oxidase; Peptides; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles	2000
The effects of sarmesin, an Angiotensin II analogue on seizure susceptibility, memory retention and nociception. Regulatory peptides, 2003, Mar-28, Volume: 111, Issue:1-3 Topics: Angiotensin II; Animals; Avoidance Learning; Disease Models, Animal; Drug Combinations; Imidazoles; Injections, Intraventricular; Kindling, Neurologic; Losartan; Male; Memory; Mice; Pain Measurement; Pentylenetetrazole; Pyridines; Seizures; Tail	2003
The effects of peptide and nonpeptide antagonists of angiotensin II receptors on the noradrenaline uptake of different brain structures in rats with angiotensin II-induced increase of water intake. Acta physiologica et pharmacologica Bulgarica, 2003, Volume: 27, Issue:2-3 Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Brain; Drinking Behavior; Imidazoles; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Saralasin; Tetrazoles	2003