angiotensin ii, des-phe(8)- has been researched along with ave 0991 in 24 studies
| Studies (angiotensin ii, des-phe(8)-) | Trials (angiotensin ii, des-phe(8)-) | Recent Studies (post-2010) (angiotensin ii, des-phe(8)-) | Studies (ave 0991) | Trials (ave 0991) | Recent Studies (post-2010) (ave 0991) |
|---|---|---|---|---|---|
| 1,533 | 21 | 995 | 48 | 0 | 33 |
| Protein | Taxonomy | angiotensin ii, des-phe(8)- (IC50) | ave 0991 (IC50) |
|---|---|---|---|
| Proto-oncogene Mas | Homo sapiens (human) | 0.021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 14 (58.33) | 24.3611 |
| 2020's | 3 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Dobrucki, LW; Heitsch, H; Louka, FR; Malinski, T; Wiemer, G | 1 |
| Derdau, V; Oekonomopulos, R; Schubert, G | 1 |
| Alenina, N; Bader, M; Bleich, M; Bontempo, ED; de Paula, RD; Mendes, EP; Pesquero, JB; Pinheiro, SV; Sampaio, WO; Santos, RA; Simões e Silva, AC; Walther, T | 1 |
| Duarte, FV; Faria-Silva, R; Santos, RA | 1 |
| Alenina, N; Bader, M; Lemos, VS; Santos, RA; Silva, DM; Walther, T | 1 |
| Heringer-Walther, S; Malberg, H; Schultheiss, HP; Walther, T; Wessel, N | 1 |
| Campagnole-Santos, MJ; Carvalho, MB; da Mata Machado, LT; de Paula, RD; Duarte, FV; Faria-Silva, R; Fauler, B; Santos, RA | 1 |
| Burns, WC; Burrell, LM; Dean, R; Thomas, MC; Velkoska, E | 1 |
| Gajda, M; Gebska, A; Guzik, TJ; Jawien, J; Korbut, R; Kus, K; Marcinkiewicz, J; Niepsuj, A; Nowak, B; Olszanecki, R; Pyka-Fosciak, G; Suski, M; Toton-Zuranska, J | 1 |
| Alzamora, AC; Campagnole-Santos, MJ; Cunha, TM; Lima, WG; Silva, ME; Souza Santos, RA | 1 |
| Almeida, JF; Alves, GM; Castro, CH; Colugnati, DB; Ferreira, AJ; Macedo, LM; Mendes, EP; Porto, JE; Santos, RA; Sobrinho, DB; Souza, ÁP; Vêncio, EF | 1 |
| Arantes, RM; Bader, M; Barroso, LC; Cisalpino, D; Dos Santos, RA; Lima, CX; Silveira, KD; Simões-E-Silva, AC; Teixeira, MM; Vieira, AT | 1 |
| Caliari, MV; Campagnole-Santos, MJ; Cara, DC; Cardoso, JA; Kangussu, LM; Lautner, RQ; Magalhães, GS; Marques, FD; Murari, A; Noviello, ML; Oliveira, ML; Pereira, JM; Rodrigues-Machado, MG; Santos, RA | 1 |
| Erfinanda, L; Gembardt, F; Kaestle, SM; Klein, N; Kuebler, WM; Lei, X; Mertens, M; Nickles, H; Supé, S; Szaszi, K; Walther, T; Wang, L; Yin, J | 1 |
| Bujak-Gizycka, B; Gebska, A; Jawien, J; Korbut, R; Kus, K; Madej, J; Olszanecki, R; Suski, M; Toton-Zuranska, J | 1 |
| Brzozowski, T; Konturek, SJ; Korbut, R; Kwiecien, S; Madej, J; Olszanecki, R; Pajdo, R; Pawlik, MW; Ptak-Belowska, A; Suski, M; Targosz, A | 1 |
| Lombard, JH; Raffai, G | 1 |
| Czesnikiewicz-Guzik, M; Guzik, TJ; Jawien, J; Korbut, R; Mikolajczyk, TP; Montezano, AC; Nosalski, R; Olszanecki, R; Rios, FJ; Siedlinski, M; Skiba, DS; Touyz, RM | 1 |
| Gao, Q; Jiang, T; Ou, Z; Shi, JQ; Wang, QG; Wu, L; Xue, LJ; Xue, X; Yang, Y; Zhang, YD | 1 |
| Cao, Y; Guo, Y; Li, Y; Liu, Y; Ping, F; Shang, J; Yao, S; Yuan, Z | 1 |
| Li, X; Li, Y; Lou, A; Su, L; Tong, H; Zhang, M; Zhu, X | 1 |
| Cao, XR; Dong, B; Hei, NH; Li, JL; Ma, H; Wang, YL; Yan, WJ | 1 |
| Balazova, L; Cacanyiova, S; Dobrocsyova, V; Krskova, K; Olszanecki, R; Slamkova, M; Suski, M; Zorad, S | 1 |
| Chen, M; Guo, Y; Hong, L; Jiang, S; Liu, S; Pan, R; Shi, J; Wang, Q; Yuan, X | 1 |
24 other study(ies) available for angiotensin ii, des-phe(8)- and ave 0991
| Article | Year |
|---|---|
AVE 0991, a nonpeptide mimic of the effects of angiotensin-(1-7) on the endothelium.
Topics: Angiotensin I; Animals; Binding, Competitive; Cattle; Cells, Cultured; Cricetinae; Electrochemistry; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Losartan; Molecular Mimicry; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptide Fragments; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Substrate Specificity; Superoxides; Tetrazoles | 2002 |
14C-labeled and large-scale synthesis of the angiotensin-(1-7)-receptor agonist AVE 0991 by cross-coupling reactions.
Topics: Angiotensin I; Carbon Radioisotopes; Catalysis; Combinatorial Chemistry Techniques; Imidazoles; Isotope Labeling; Molecular Structure; Peptide Fragments; Receptors, Angiotensin; Thiophenes | 2003 |
Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney.
Topics: Angiotensin I; Animals; Blood Pressure; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Diuresis; Imidazoles; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Transfection | 2004 |
Short-term angiotensin(1-7) receptor MAS stimulation improves endothelial function in normotensive rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reference Values; Vasodilator Agents | 2005 |
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
The angiotensin-(1-7) receptor agonist AVE0991 dominates the circadian rhythm and baroreflex in spontaneously hypertensive rats.
Topics: Angiotensin I; Animals; Baroreflex; Blood Pressure; Circadian Rhythm; Heart Rate; Imidazoles; Male; Peptide Fragments; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Renin-Angiotensin System | 2007 |
Evidence for Mas-mediated bradykinin potentiation by the angiotensin-(1-7) nonpeptide mimic AVE 0991 in normotensive rats.
Topics: Angiotensin I; Angiotensin II; Animals; Bradykinin; Dose-Response Relationship, Drug; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Hypotension; Imidazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rabbits; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Vasodilator Agents | 2007 |
Angiotensin II mediates epithelial-to-mesenchymal transformation in tubular cells by ANG 1-7/MAS-1-dependent pathways.
Topics: Actins; Angiotensin I; Angiotensin II; Animals; Cadherins; Cell Differentiation; Cell Line; Epithelial Cells; Imidazoles; Kidney Tubules; Mesoderm; Models, Animal; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Transforming Growth Factor beta1 | 2010 |
Angiotensin-(1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice.
Topics: Angiotensin I; Animals; Antigens, CD; Aorta; Apolipoproteins E; Atherosclerosis; CD4-Positive T-Lymphocytes; Dendritic Cells; Female; Imidazoles; Lipids; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptide Fragments; Perindopril; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, Angiotensin; Receptors, G-Protein-Coupled; Thiorphan | 2012 |
The nonpeptide ANG-(1-7) mimic AVE 0991 attenuates cardiac remodeling and improves baroreflex sensitivity in renovascular hypertensive rats.
Topics: Angiotensin I; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rate; Hypertension, Renovascular; Imidazoles; Kidney; Male; Myocardium; Peptide Fragments; Rats; Rats, Inbred F344; Ventricular Remodeling | 2013 |
Angiotensin II type 1 receptor blockade restores angiotensin-(1-7)-induced coronary vasodilation in hypertrophic rat hearts.
Topics: Angiotensin I; Animals; Cardiomegaly; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Rats; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Vasodilation | 2013 |
Beneficial effects of the activation of the angiotensin-(1-7) MAS receptor in a murine model of adriamycin-induced nephropathy.
Topics: Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Models, Animal; Doxorubicin; Gene Expression Regulation; Humans; Imidazoles; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Losartan; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; RNA, Messenger; Time Factors | 2013 |
AVE 0991, a non-peptide mimic of angiotensin-(1-7) effects, attenuates pulmonary remodelling in a model of chronic asthma.
Topics: Airway Remodeling; Angiotensin I; Angiotensin II; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chronic Disease; Cytokines; Disease Models, Animal; Hypertrophy, Right Ventricular; Imidazoles; Lung; Male; Mice; Mice, Inbred BALB C; Molecular Mimicry; Ovalbumin; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Artery; Pulmonary Veins; Receptors, G-Protein-Coupled; Time Factors | 2013 |
Angiotensin-(1-7) protects from experimental acute lung injury.
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electric Impedance; Endothelial Cells; Hemodynamics; Imidazoles; Irbesartan; Male; Mice; Mice, Inbred C57BL; Peptide Fragments; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Respiratory Mechanics; Tetrazoles | 2013 |
The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Benzopyrans; Down-Regulation; Drug Therapy, Combination; Ethanolamines; Female; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Nebivolol; Peptide Fragments; Renin-Angiotensin System; Vasodilator Agents | 2013 |
The renin-angiotensin system and its vasoactive metabolite angiotensin-(1-7) in the mechanism of the healing of preexisting gastric ulcers. The involvement of Mas receptors, nitric oxide, prostaglandins and proinflammatory cytokines.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cytokines; Enzyme Inhibitors; Gastric Mucosa; Imidazoles; Indomethacin; Interleukin-1beta; Lisinopril; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats.
Topics: Acetylcholine; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Nitric Oxide; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Chloride, Dietary; Vasodilation; Vasodilator Agents | 2016 |
Anti-atherosclerotic effect of the angiotensin 1-7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis.
Topics: Angiotensin I; Animals; Anti-Inflammatory Agents; Aorta; Atherosclerosis; Cell Line; Cell Line, Tumor; Cytokines; Female; Humans; Imidazoles; Leukocytes; Macrophages; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments; Plaque, Atherosclerotic; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2017 |
AVE0991, a nonpeptide analogue of Ang-(1-7), attenuates aging-related neuroinflammation.
Topics: Aging; Angiotensin I; Animals; Brain; Imidazoles; Inflammation; Mice; Microglia; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled | 2018 |
Ang-(1-7) treatment attenuates lipopolysaccharide-induced early pulmonary fibrosis.
Topics: Angiotensin I; Angiotensin II; Animals; Bronchoalveolar Lavage Fluid; Cadherins; Drug Evaluation, Preclinical; Imidazoles; Lipopolysaccharides; Lung; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pulmonary Fibrosis; Random Allocation; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Transforming Growth Factor beta; Vasodilator Agents; Vimentin | 2019 |
AVE 0991 Attenuates Pyroptosis and Liver Damage after Heatstroke by Inhibiting the ROS-NLRP3 Inflammatory Signalling Pathway.
Topics: Angiotensin I; Angiotensin II; Animals; Biomarkers; Heat Stroke; Hepatocytes; Humans; Imidazoles; Inflammasomes; Inflammation; Interleukin-1beta; Liver; Liver Cirrhosis; Male; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments; Prospective Studies; Pyroptosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction | 2019 |
AVE0991, a nonpeptide angiotensin-(1-7) mimic, inhibits angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aortic Aneurysm, Abdominal; Apolipoproteins E; Blood Pressure; Disease Models, Animal; Humans; Imidazoles; Immunohistochemistry; Lipids; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Knockout; Molecular Mimicry; Myocytes, Smooth Muscle; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptide Fragments | 2020 |
AVE0991, a Nonpeptide Angiotensin 1-7 Receptor Agonist, Improves Glucose Metabolism in the Skeletal Muscle of Obese Zucker Rats: Possible Involvement of Prooxidant/Antioxidant Mechanisms.
Topics: Angiotensin I; Animals; Antioxidants; Glucose; Imidazoles; Male; Peptide Fragments; Rats; Rats, Zucker | 2020 |
Mas receptor activation attenuates allergic airway inflammation via inhibiting JNK/CCL2-induced macrophage recruitment.
Topics: Acute Disease; Angiotensin I; Animals; Asthma; Chemokine CCL2; Cytokines; Imidazoles; Inflammation; Macrophage Activation; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Ovalbumin; Peptide Fragments; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Respiratory System | 2021 |