Page last updated: 2024-09-05

anemodeanin a and beta-escin

anemodeanin a has been researched along with beta-escin in 22 studies

Compound Research Comparison

Studies
(anemodeanin a)
Trials
(anemodeanin a)
Recent Studies (post-2010)
(anemodeanin a)
Studies
(beta-escin)
Trials
(beta-escin)
Recent Studies (post-2010) (beta-escin)
2902714,1372116,278

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (63.64)24.3611
2020's8 (36.36)2.80

Authors

AuthorsStudies
Sun, W; Wang, RP; Wu, J; Xu, JL; Xue, G; Zhou, JY; Zou, X1
Chen, QL; Guan, JL; Qian, S; Wang, ZY; Wu, Y1
Chen, HZ; Fang, C; Gao, YG; Guan, YY; Liu, HJ; Liu, YR; Lu, Q; Luan, X; Xu, JR; Zhao, M1
Cai, GZ; Gong, JY; Li, JN; Li, ZM; Yu, Y; Zhang, YF1
Peng, Z; Wu, C; Zhang, C; Zhang, Y; Zhou, W1
Cheng, Y; Guan, YD; Jiang, SL; Wen, M; Xiao, SS; Xu, XJ; Yu, P; Zhang, Y1
Chen, S; Fan, S; Feng, M; He, W; Huang, K; Ma, J; Mo, J; Wang, J; Wang, Q; Xie, Z; Zhao, C1
Hou, X; Liu, Y; Ouyang, Z; Peng, F; Shen, C; Shu, M; Wang, L; Wang, X; Yang, M; Zhang, LW; Zhao, B; Zhao, S1
Ma, B; Wang, Y; Zhang, H; Zhang, J; Zhang, L; Zhang, Q; Zhao, A; Zhu, J1
Bao, X; Ma, B; Wang, Y; Zhang, J; Zhang, M; Zhang, Q; Zhao, A1
Cai, Z; Hua, Y; Mao, M; Sun, W; Wang, C; Wang, G; Wang, H; Wang, Z; Xu, J; Yin, F; Zhang, T; Zhou, Z; Zuo, D1
Bai, S; Dong, Y; Hu, C; Lyu, J; Xia, H; Yu, X; Zhan, Y; Zhang, BY; Zhao, L1
Cai, Z; Hua, Y; Mao, M; Shen, J; Sun, W; Wang, G; Wang, H; Wang, Z; Xu, J; Yin, F; Zhang, T; Zhou, Z; Zuo, D1
Fan, QX; Guo, SS; Wang, Y1
Ahn, KS; Khan, MR; Naz, I; Ramchandani, S; Yang, MH1
Jin, W; Lu, S; Shi, H; Shu, Y; Wang, X1
He, Y; Li, L; Lv, X; Ma, J; Shen, X1
Cheng, H; Dai, X; Wang, B; Wang, W; Wu, B; Ye, L; Zhu, J1
Cai, GZ; Gong, JY; Jiang, CF; Li, JN; Liu, X; Wang, YY1
Cai, R; Chen, M; Li, G; Li, L1
Cao, XW; Kang, JY; Wang, FJ; Zhao, J1
Hei, B; Liu, RE; Miao, Z; Ouyang, J; Wang, D; Zhou, J1

Reviews

1 review(s) available for anemodeanin a and beta-escin

ArticleYear
Anticancer Potential of Raddeanin A, a Natural Triterpenoid Isolated from
    Molecules (Basel, Switzerland), 2020, Feb-25, Volume: 25, Issue:5

    Topics: Anemone; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Humans; Saponins; Triterpenes; Wnt Signaling Pathway

2020

Other Studies

21 other study(ies) available for anemodeanin a and beta-escin

ArticleYear
Raddeanin A induces human gastric cancer cells apoptosis and inhibits their invasion in vitro.
    Biochemical and biophysical research communications, 2013, Sep-20, Volume: 439, Issue:2

    Topics: Anemone; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Invasiveness; RNA, Messenger; Saponins; Stomach; Stomach Neoplasms

2013
Synthesis and biological evaluation of Raddeanin A, a triterpene saponin isolated from Anemone raddeana.
    Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:8

    Topics: Anemone; Antineoplastic Agents; HeLa Cells; Histone Deacetylase Inhibitors; Humans; Saponins

2014
Raddeanin A, a triterpenoid saponin isolated from Anemone raddeana, suppresses the angiogenesis and growth of human colorectal tumor by inhibiting VEGFR2 signaling.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2015, Jan-15, Volume: 22, Issue:1

    Topics: Anemone; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chick Embryo; Colorectal Neoplasms; Female; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Molecular Docking Simulation; Neovascularization, Pathologic; Saponins; Signal Transduction; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays; Zebrafish

2015
Synergy of Raddeanin A and cisplatin induced therapeutic effect enhancement in human hepatocellular carcinoma.
    Biochemical and biophysical research communications, 2017, 04-01, Volume: 485, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Liver; Liver Neoplasms; Reactive Oxygen Species; Saponins

2017
The STAT3/NFIL3 signaling axis-mediated chemotherapy resistance is reversed by Raddeanin A via inducing apoptosis in choriocarcinoma cells.
    Journal of cellular physiology, 2018, Volume: 233, Issue:7

    Topics: Apoptosis; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Cell Survival; Choriocarcinoma; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Saponins; Signal Transduction; STAT3 Transcription Factor

2018
Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of raddeanin A against human breast cancer cells in vitro.
    Acta pharmacologica Sinica, 2018, Volume: 39, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Breast Neoplasms; Cell Line, Tumor; Chloroquine; Down-Regulation; Elongation Factor 2 Kinase; Female; Heterocyclic Compounds, 3-Ring; Humans; Proto-Oncogene Proteins c-akt; Saponins; Signal Transduction; TOR Serine-Threonine Kinases

2018
Raddeanin A suppresses breast cancer-associated osteolysis through inhibiting osteoclasts and breast cancer cells.
    Cell death & disease, 2018, 03-07, Volume: 9, Issue:3

    Topics: Animals; Blotting, Western; Bone Resorption; Breast Neoplasms; Cell Survival; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Saponins

2018
Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:3

    Topics: Apoptosis; Cell Line, Tumor; Enzyme Activation; Glioblastoma; Humans; MAP Kinase Kinase 4; Neoplasm Proteins; Reactive Oxygen Species; Saponins

2018
Raddeanin A, a natural triterpenoid saponin compound, exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway.
    Toxicology and applied pharmacology, 2018, 08-15, Volume: 353

    Topics: Anemone; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Humans; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Neoplasm Invasiveness; NF-kappa B; Osteosarcoma; Reactive Oxygen Species; Saponins; Signal Transduction; Xenograft Model Antitumor Assays

2018
Raddeanin A inhibits growth and induces apoptosis in human colorectal cancer through downregulating the Wnt/β-catenin and NF-κB signaling pathway.
    Life sciences, 2018, Aug-15, Volume: 207

    Topics: Animals; Antineoplastic Agents; Apoptosis; beta Catenin; Caco-2 Cells; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Down-Regulation; Humans; Male; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; NF-kappa B p50 Subunit; Phosphorylation; RNA, Small Interfering; Saponins; Triterpenes; Wnt Proteins; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2018
Attenuation of STAT3 Phosphorylation Promotes Apoptosis and Chemosensitivity in Human Osteosarcoma Induced by Raddeanin A.
    International journal of biological sciences, 2019, Volume: 15, Issue:3

    Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cell Survival; Female; Flow Cytometry; Humans; In Situ Nick-End Labeling; Interleukin-6; Mice; Mice, Inbred BALB C; Osteosarcoma; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Saponins; STAT3 Transcription Factor

2019
Raddeanin A down-regulates androgen receptor and its splice variants in prostate cancer.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Docetaxel; Down-Regulation; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; PC-3 Cells; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Protein Isoforms; Receptors, Androgen; RNA Splicing; Saponins

2019
Antitumor activity of Raddeanin A is mediated by Jun amino-terminal kinase activation and signal transducer and activator of transcription 3 inhibition in human osteosarcoma.
    Cancer science, 2019, Volume: 110, Issue:5

    Topics: Animals; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Signaling System; Mice; Osteosarcoma; Reactive Oxygen Species; Saponins; STAT3 Transcription Factor; Time Factors; Xenograft Model Antitumor Assays

2019
Raddeanin A promotes apoptosis and ameliorates 5-fluorouracil resistance in cholangiocarcinoma cells.
    World journal of gastroenterology, 2019, Jul-14, Volume: 25, Issue:26

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Cholangiocarcinoma; Drug Resistance, Neoplasm; Fluorouracil; Humans; Saponins

2019
Raddeanin A suppresses lung cancer cell proliferation via induction of apoptosis and increased production of ROS.
    Cellular and molecular biology (Noisy-le-Grand, France), 2020, Oct-31, Volume: 66, Issue:7

    Topics: Acetylcysteine; Apoptosis; bcl-2-Associated X Protein; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species; Saponins

2020
Raddeanin A inhibits proliferation, invasion, migration and promotes apoptosis of cervical cancer cells via regulating miR-224-3p/Slit2/Robo1 signaling pathway.
    Aging, 2021, 02-17, Volume: 13, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Movement; Cell Proliferation; Female; Humans; Intercellular Signaling Peptides and Proteins; MicroRNAs; Neoplasm Invasiveness; Nerve Tissue Proteins; Receptors, Immunologic; Roundabout Proteins; Saponins; Signal Transduction; Tumor Cells, Cultured; Up-Regulation; Uterine Cervical Neoplasms

2021
Raddeanin A inhibited epithelial-mesenchymal transition (EMT) and angiogenesis in glioblastoma by downregulating β-catenin expression.
    International journal of medical sciences, 2021, Volume: 18, Issue:7

    Topics: Animals; beta Catenin; Brain Neoplasms; Cell Proliferation; Down-Regulation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Mice; Neovascularization, Pathologic; Saponins; Vascular Endothelial Growth Factor A; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2021
The study of Raddeanin A cerebrovascular endothelial cell trafficking through P-glycoprotein.
    Biochemical and biophysical research communications, 2021, 06-25, Volume: 559

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Drug Resistance; Endothelial Cells; Humans; Intracellular Space; Microvessels; Saponins

2021
Raddeanin A induced apoptosis of non-small cell lung cancer cells by promoting ROS-mediated STAT3 inactivation.
    Tissue & cell, 2021, Volume: 71

    Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Neoplasm Proteins; Reactive Oxygen Species; Saponins; STAT3 Transcription Factor

2021
Raddeanin A synergistically enhances the anti-tumor effect of MAP30 in multiple ways, more than promoting endosomal escape.
    Toxicology and applied pharmacology, 2022, 08-15, Volume: 449

    Topics: Endosomes; Humans; Neoplasms; Ribosome Inactivating Proteins, Type 2; Saponins; Triterpenes

2022
Raddeanin A (RA) reduced acute inflammatory injury in mouse experimental cerebral hemorrhage by suppression of TLR4.
    International journal of medical sciences, 2022, Volume: 19, Issue:8

    Topics: Animals; Brain Edema; Cerebral Hemorrhage; Mice; Microglia; Saponins; Toll-Like Receptor 4

2022