Page last updated: 2024-08-17

androstenedione and plomestane

androstenedione has been researched along with plomestane in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (53.85)	18.7374
1990's	12 (46.15)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bednarski, PJ; Nelson, SD	1
di Salle, E; Giudici, D; Ornati, G; Panzeri, A; Zaccheo, T	1
Johnston, JO; Leeson, GA; Wright, CL	1
Gomez-Sanchez, CE; Gomez-Sanchez, EP	1
Doody, KM; Mason, JI; Murry, BA	1
Griffing, GT; Holbrook, M; Johnston, ON; Melby, JC	1
Brandt, ME; Brodie, AM; Melner, MH; Puett, D; Zimniski, SJ	1
Benson, HD; Holbert, GW; Johnston, JO; Wright, CL	1
Brandt, ME; Covey, DF; Zimniski, SJ	1
Briatico, G; di Salle, E; Giudici, D; Ornati, G	1
Briatico, G; di Salle, E; Giudici, D; Ornati, G; Zaccheo, T	1
Alberta, J; Griffing, GT; Holbrook, M; Melby, JC; Orme-Johnson, NR	1
Johnston, JO; Shumaker, RC; Wright, CL	1
Brandt, ME; Covey, DF; Fendl, K; Garola, R; Puett, D; Zimniski, SJ	1
Femino, A; Johnston, JO; Longcope, C	1
Brandt, ME; Covey, DF; Puett, D; Zimniski, SJ	2
Berkovitz, GD; Brown, TR; Kruter, RH; Migeon, CJ	1
Griffing, GT; Holbrook, M; Johnston, JO; Melby, JC	1
Brandt, ME; Covey, DF; Melner, MH; Puett, D; Zimniski, SJ	1
Johnston, JO; Metcalf, BW; Wright, CL	2
Covey, DF; Etre, LA; MacIndoe, JH; Woods, GR	1
Covey, DF; Davis, SP; Killinger, DW; Perel, E	1
Holbert, GW; Johnston, JO; Wright, CL	1
Brodie, AM	1

Reviews

2 review(s) available for androstenedione and plomestane

Article	Year
Aromatase and aromatase inhibitors: from enzymology to selective chemotherapy. Progress in clinical and biological research, 1988, Volume: 262 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Pargyline; Rats	1988
Aromatase, its inhibitors and their use in breast cancer treatment. Pharmacology & therapeutics, 1993, Volume: 60, Issue:3 Topics: Aminoglutethimide; Androstenedione; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Half-Life; Humans; Neoplasms, Hormone-Dependent; Pargyline	1993

Trials

1 trial(s) available for androstenedione and plomestane

Article	Year
Enzyme-activated inhibitors of steroidal hydroxylases. The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:1 Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Aromatase Inhibitors; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Drug Tolerance; Estrogens; Humans; Male; Mineralocorticoids; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Zona Glomerulosa	1995

Article

Year

Enzyme-activated inhibitors of steroidal hydroxylases.

The Journal of steroid biochemistry and molecular biology, 1995, Volume: 52, Issue:1

Topics: Adrenal Cortex Hormones; Androstenedione; Animals; Aromatase Inhibitors; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Drug Tolerance; Estrogens; Humans; Male; Mineralocorticoids; Pargyline; Rats; Rats, Sprague-Dawley; Receptors, Steroid; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Zona Glomerulosa

1995

Other Studies

23 other study(ies) available for androstenedione and plomestane

Article	Year
Interactions of thiol-containing androgens with human placental aromatase. Journal of medicinal chemistry, 1989, Volume: 32, Issue:1 Topics: Androstenedione; Aromatase Inhibitors; Chemical Phenomena; Chemistry; Drug Interactions; Female; Humans; In Vitro Techniques; Microsomes; Paraoxon; Placenta; Pregnancy; Structure-Activity Relationship; Sulfhydryl Compounds; Testosterone Congeners	1989
Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:9 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Dose-Response Relationship, Drug; Endocrine Glands; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Pargyline; Prolactin; Rats	1991
Regioselectivity of metabolic activation of acetylenic steroids by hepatic cytochrome P450 isozymes. Steroids, 1991, Volume: 56, Issue:4 Topics: Androstenedione; Animals; Aromatase Inhibitors; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Isoenzymes; Liver; Male; Norethindrone; Pargyline; Pentobarbital; Rats; Rats, Inbred Strains; Sleep	1991
The effect of gonadectomy and aromatase inhibition on the excretion of 19-nordeoxycorticosterone in rats. The Journal of steroid biochemistry and molecular biology, 1991, Volume: 39, Issue:2 Topics: Androstenedione; Animals; Aromatase Inhibitors; Castration; Desoxycorticosterone; Estrogens; Female; Gonads; Male; Pargyline; Rats; Testosterone	1991
The use of rat Leydig tumor (R2C) and human hepatoma (HEPG2) cells to evaluate potential inhibitors of rat and human steroid aromatase. Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma, Hepatocellular; Cell Line; Drug Screening Assays, Antitumor; Humans; Kinetics; Leydig Cell Tumor; Liver Neoplasms; Male; Pargyline; Rats; Testicular Neoplasms	1990
Antihypertensive effects of an aromatase inhibitor in inbred salt-sensitive rats. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 1 Topics: Aldosterone; Androstenedione; Animals; Antihypertensive Agents; Aromatase Inhibitors; Cortisone; Desoxycorticosterone; Female; Hypertension; Male; Pargyline; Rats; Rats, Inbred Strains; Sodium Chloride	1991
Effect of 4-hydroxyandrostenedione on murine Leydig tumor cell steroidogenesis. Cancer research, 1991, Jul-15, Volume: 51, Issue:14 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Pargyline; Pregnenolone; Progesterone; Testosterone	1991
Enzyme inactivation by potential metabolites of an aromatase-activated inhibitor (MDL 18,962). Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Biotransformation; Female; Humans; Indicators and Reagents; Kinetics; Microsomes; Pargyline; Placenta; Structure-Activity Relationship	1990
The effects of in vivo administration of 10-propargylestr-4-ene-3,17-dione on rat ovarian aromatase and estrogen levels. Journal of enzyme inhibition, 1990, Volume: 4, Issue:2 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Estradiol; Estrogens; Estrus; Female; Injections, Subcutaneous; Kinetics; Ovary; Pargyline; Proestrus; Rats; Reference Values	1990
Novel irreversible aromatase inhibitors. Annals of the New York Academy of Sciences, 1990, Volume: 595 Topics: Aminoglutethimide; Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; In Vitro Techniques; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Rats; Rats, Inbred Strains	1990
Aromatase inhibition and experimental antitumor activity of FCE 24304, MDL 18962 and SH 489. Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Female; Humans; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Microsomes; Orchiectomy; Ovary; Pargyline; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Reference Values	1989
19-Hydroxylase inhibition of adrenal mitochondrial P450 11 beta/18/19-hydroxylase by a suicide inhibitor. The American journal of the medical sciences, 1989, Volume: 298, Issue:2 Topics: Adrenal Glands; Adrenodoxin; Androstenedione; Animals; Cattle; Cytochrome P-450 CYP11B2; Cytochrome P-450 Enzyme Inhibitors; Desoxycorticosterone; Ferredoxin-NADP Reductase; Hydroxylation; In Vitro Techniques; Mitochondria; Pargyline; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases	1989
Human trophoblast xenografts in athymic mice: a model for peripheral aromatization. Journal of steroid biochemistry, 1989, Volume: 33, Issue:4A Topics: Androstenedione; Animals; Aromatase Inhibitors; Choriocarcinoma; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Ovary; Pargyline; Pregnancy; Tissue Distribution; Tumor Cells, Cultured	1989
Inhibition of peripheral aromatization in baboons by an enzyme-activated aromatase inhibitor (MDL 18,962). Endocrinology, 1988, Volume: 122, Issue:5 Topics: Androstenedione; Animals; Aromatase Inhibitors; Carbon Radioisotopes; Estradiol; Estrone; Female; Kinetics; Metabolic Clearance Rate; Papio; Pargyline; Reference Values; Testosterone; Tritium	1988
Characterization of pregnant mare's serum gonadotropin-stimulated rat ovarian aromatase and its inhibition by 10-propargylestr-4-ene-3,17-dione. Journal of steroid biochemistry, 1988, Volume: 31, Issue:3 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Pregnancy; Rats; Reference Values	1988
Effects of 10-(2-propynyl)-estr-4-ene-3,17-dione (MDL 18,962)--a mechanism-based irreversible inhibitor of aromatase--in cultured human foreskin fibroblasts. Journal of steroid biochemistry, 1987, Volume: 28, Issue:2 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Adult; Androstenedione; Aromatase Inhibitors; Cells, Cultured; Dihydrotestosterone; Fibroblasts; Humans; Infant, Newborn; Male; Pargyline; Penis; Receptors, Androgen; Skin	1987
Antihypertensive effects of an aromatase inhibitor in the spontaneously hypertensive rat. Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:5 Topics: Aging; Androstenedione; Animals; Blood Pressure; Desoxycorticosterone; Hypertension; Male; Pargyline; Rats; Rats, Inbred SHR	1987
Inhibition of Leydig tumor cell steroidogenesis by 10-propargylestr-4-ene-3,17-dione, an irreversible aromatase inhibitor. Cancer research, 1985, Volume: 45, Issue:10 Topics: Androstenedione; Animals; Aromatase Inhibitors; Leydig Cell Tumor; Male; Mice; Mice, Inbred C57BL; Oxidoreductases; Pargyline; Pregnenolone; Progesterone; Testicular Neoplasms; Testosterone	1985
Time-dependent inhibition of aromatase in trophoblastic tumor cells in tissue culture. Journal of steroid biochemistry, 1984, Volume: 20, Issue:6A Topics: Androstenedione; Aromatase Inhibitors; Cell Line; Choriocarcinoma; Estrogens; Female; Humans; Kinetics; Oxidoreductases; Pargyline; Pregnancy; Uterine Neoplasms	1984
Biochemical and endocrine properties of a mechanism-based inhibitor of aromatase. Endocrinology, 1984, Volume: 115, Issue:2 Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Biomechanical Phenomena; Chemical Phenomena; Chemistry; Endocrine Glands; Enzyme Inhibitors; Female; Humans; Male; Mice; Mice, Inbred Strains; Ovary; Oxidoreductases; Pargyline; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1984
Comparative studies of aromatase inhibitors in cultured human breast cancer cells. Cancer research, 1982, Volume: 42, Issue:8 Suppl Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Cell Line; Dihydrotestosterone; Estradiol; Female; Humans; Oxidoreductases; Pargyline; Receptors, Estrogen; Receptors, Progesterone; Testolactone; Testosterone	1982
Effects of 4-hydroxy-4-androstene-3, 17-dione and 10-propargylestr-4-ene-3, 17-dione on the metabolism of androstenedione in human breast carcinoma and breast adipose tissues. Steroids, 1981, Volume: 38, Issue:4 Topics: Adipose Tissue; Androstenedione; Breast; Breast Neoplasms; Female; Humans; Kinetics; Pargyline	1981
Inhibition of growth and appearance of estrogen-dependent rat mammary tumors by 10-propargylestr-4-ene-3,17-dione, an aromatase inhibitor. Breast cancer research and treatment, 1993, Volume: 26, Issue:1 Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogens; Estrus; Female; Mammary Neoplasms, Experimental; Neoplasms, Hormone-Dependent; Pargyline; Rats; Rats, Sprague-Dawley	1993