androstenedione has been researched along with nadp in 117 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 83 (70.94) | 18.7374 |
1990's | 22 (18.80) | 18.2507 |
2000's | 11 (9.40) | 29.6817 |
2010's | 1 (0.85) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ackerman, RJ; Hamilton, DW | 1 |
Andersen, RN; Givens, JR; Pittaway, DE | 2 |
Juchau, MR; Mirkin, DL; Zachariah, PK | 1 |
Bedrak, E; Slonim, A | 1 |
Bedrak, E; Chap, Z | 1 |
Bedrak, E; Chap, Z; Slonim, A | 1 |
Hoyer, PE; Moller, M | 1 |
Oshima, H; Paraska, L; Troen, P; Yoshida, KI | 1 |
Meigs, RA; Moorthy, KB | 1 |
Goebelsmann, U; Nakamura, RM; Stanczyk, FZ | 1 |
Altman, K; Gordon, GG; Hagedorn, J; Rappaport, SC; Southren, AL; Vittek, J | 1 |
Geiss, M; Pirke, KM; Vogt, HJ | 1 |
Fan, DF; Hartsock, RJ; VanCura, S | 1 |
Dvorchik, BH; Hartman, RD; Marietta, MP; Vesell, ES; Weisz, J | 1 |
Atrat, P; Deppmeyer, V; Groh, H; Hörhold, C; Komel, R | 1 |
Matsumoto, K; Mizutani, S; Tsujimura, T | 1 |
Nimrod, A; Ryan, KJ | 1 |
Fan, DF; Oshima, H; Troen, P | 1 |
Inano, H; Tamaoki, B | 1 |
Cameron, EH; Collins, W | 1 |
Juchau, MR; Zachariah, PK | 1 |
Ernster, L; Gustafsson, JA; Hrycay, EG; Ingelman-Sundberg, M | 1 |
Lübbert, H; Pollow, B; Pollow, K | 1 |
Burkhart, JP; Johnston, JO; Peet, NP; Wright, CL | 1 |
Hudson, RW; Wherrett, D | 1 |
López-Solache, I; Mendoza-Hernández, G; Rendón, JL | 1 |
Brueggemeier, RW; Li, PK | 1 |
Horsfield, BP; Murray, M | 1 |
Sugimoto, Y; Tamaoki, B; Yoshida, M | 1 |
Davenport, JD; Hirsch, KS; Holden, HE; Jones, CD; Krumkalns, EV; Stamm, N; Suhr, RG; Taylor, HM; Winter, MA | 1 |
Cole, PA; Robinson, CH | 1 |
Katagiri, M; Suhara, K; Yamamoto, M | 1 |
Galbraith, RA; Jellinck, PH | 1 |
Boussioux, AM; Chikhaoui, Y; Chitour, F; Crastes de Paulet, A; Descomps, B; Nicolas, JC | 1 |
Attisano, C; Guengerich, FP; Lapenson, DP; Waxman, DJ | 1 |
Itagaki, E | 1 |
Bezwoda, WR; Dansey, R; Esser, JD; Mansoor, N | 1 |
Coon, MJ; Osawa, Y | 1 |
Katagiri, M; Suhara, K; Takeda, K | 1 |
Muto, N; Tan, L | 1 |
Lundmo, PI; Sunde, A; Tveter, KJ | 1 |
Petit, A; Tan, L | 1 |
Aw, TY; Jones, DP; O'Shannessy, DJ; Priest, JH; Priest, RE | 1 |
Lloyd, JW; Mawhinney, MG; Schwartz, FL; Thomas, JA | 1 |
Chakraborty, J; Hopkins, R; Parke, DV | 1 |
Einarsson, K; Gustafsson, BE; Gustafsson, JA | 2 |
Ghraf, R; Hoff, HG; Lax, ER; Schriefers, H | 1 |
Lerner, N; Lunenfeld, B; Sulimovici, S | 1 |
Moore, RJ; Wilson, JD | 1 |
Oliver, JF; Renwick, AG | 1 |
Cameron, EH; Maynard, PV | 1 |
Engelhardt, D; Karl, HJ | 1 |
Karl, HJ; Raith, L | 1 |
Bedrak, E; Samoiloff, V; Sod-Moriah, UA | 1 |
Coffey, JC | 1 |
O, R; Tamaoki, BI | 1 |
Oh, R; Tamaoki, B | 1 |
Fouchet, C; Ozon, R | 1 |
Deshpande, N; Yates, J | 1 |
Jaffe, RB; Kawano, A; Payne, AH | 1 |
Nozu, K; Tamaoki, B | 1 |
Bellino, FL; Osawa, Y | 2 |
Ochiai, K; Oshima, H; Sarada, T; Tamaoki, B | 1 |
Inano, H | 1 |
Siiteri, PK; Thompson, EA | 2 |
O'Brien, PJ; Rahimtula, AD | 1 |
Aronin, PA; Coffey, JC; French, FS; Nayfeh, SN | 1 |
Pérez Lloret, A; Weisz, J | 1 |
Hoff, HG; Schriefers, H | 1 |
Pollow, B; Pollow, K; Schmalbeck, J; Sokolowski, G | 1 |
Braselton, WE; Engel, LL; Orr, JC | 1 |
Katukawa, H; Nakamura, T; Tanabe, Y | 1 |
Donnelly, JB; Hay, JB; Hodgins, MB | 1 |
Andersen, RN; Coleman, SA; Givens, JR; Pittaway, DE; Wiser, WL | 1 |
Brent, RL; Koszalka, TR; Sheth, K | 1 |
Beusen, DD; Carrell, HL; Covey, DF; Hood, WF | 1 |
Gévry, G; Navennec, P; Tan, L | 1 |
Hamana, K; Inano, H; Nakagawa, H; Tamaoki, B | 1 |
Leinonen, P | 1 |
Inano, H; Ohba, H; Tamaoki, B | 1 |
Kochakian, CD | 2 |
Sholl, SA | 1 |
Jayle, MF; Le Guern, A; Longchampt, J | 1 |
Chen, GT; MacDonald, PC; Milewich, L; Peterson, JA | 1 |
Golf, SW; Graef, V; Tüschen, M | 1 |
Meigs, RA; Sheean, LA | 1 |
Frenkel, RA; Hendricks, TS; MacDonald, PC; Masters, BS; Milewich, L | 1 |
Kominami, S; Tagashira, H; Takemori, S | 1 |
Coon, MJ; Ding, X | 1 |
Fjösne, HE; Haug, E; Sunde, A | 1 |
Butler, AM; Murray, M | 2 |
Numazawa, M; Oshibe, M; Tachibana, M; Yamaguchi, S | 1 |
Achstetter, T; Cauet, G; Degryse, E; Dumas, B; Lacour, T; Laruelle, L; Ledoux, C; Spagnoli, R | 1 |
Bates, JN; Holmes, RW; Snyder, GD; Van Voorhis, BJ | 1 |
Düerkop, J; Hartmann, RW; Njar, VC | 1 |
Bos-Zuur, I; de la Rivière, GB; Dikkeschei, LD; Nagel, GT; van der Kolk, DA; Willemse, PH; Wolthers, BG | 1 |
Numazawa, M; Tachibana, M | 2 |
Kühn-Velten, WN; Pippirs, U | 1 |
Numazawa, M; Yamada, K | 1 |
Bidlingmaier, F; Clusmann, H; Elger, CE; Hans, VH; Klingmüller, D; Redel, L; Steckelbroeck, S; Stoffel-Wagner, B; Watzka, M | 1 |
Adamski, J; Rizner, TL; Stojan, J | 1 |
Heidrich, DD; Klingmuller, D; Steckelbroeck, S | 1 |
Ishikawa, M; Numazawa, M; Shelangouski, M; Tachibana, M; Yoshimura, A | 1 |
James, MO; Johnson, JV; Lou, Z | 1 |
Atkinson, MJ; Atkinson, S; Blomquist, CH; Lima, PH; Tarrant, AM | 1 |
Labrie, F; Lin, SX; Qiu, W; Zhou, M | 1 |
Matthews, J; Novak, D; Quiggle, F | 1 |
Donova, MV; Dovbnya, DV; Egorova, OV; Nikolayeva, VM | 1 |
Clark, DT; Soory, M | 1 |
Ge, RS; Hardy, MP; Latif, SA; Morris, DJ; Shen, M; Sottas, CM | 1 |
117 other study(ies) available for androstenedione and nadp
Article | Year |
---|---|
Testosterone metabolism in male rat epiphysis.
Topics: Androstane-3,17-diol; Androstenedione; Animals; Cytosol; Dihydrotestosterone; Epiphyses; Male; NADP; Nucleoproteins; Protein Binding; Rats; Subcellular Fractions; Testosterone | 1976 |
Deficient 17 beta-hydroxysteroid oxidoreductase activity in testes from a male pseudohermaphrodite.
Topics: Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Hydroxysteroid Dehydrogenases; Luteinizing Hormone; Male; Microsomes; NAD; NADP; Testis | 1976 |
Interactions of various 19-nor steroids with human placental microsomal cytochrome P-450 (P-450hpm).
Topics: Androstenedione; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Microsomes; NADP; Norsteroids; Placenta; Pregnancy; Protein Binding; Testosterone | 1976 |
Activity of enzymes associated with the biosynthesis of testosterone by gonads of the old mouse.
Topics: Aging; Algestone; Androstenedione; Animals; Body Weight; Desoxycorticosterone; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Male; Mice; Mice, Inbred C57BL; NAD; NADP; Organ Size; Progesterone; Steroid Hydroxylases; Testis; Testosterone | 1977 |
In vitro testosterone synthesis by testicular tissue of old mouse: the metabolism of 3beta-hydroxy-5-ene steroids.
Topics: 17-alpha-Hydroxypregnenolone; Aging; Androgens; Androstenediols; Androstenedione; Animals; Dehydroepiandrosterone; Hydroxyprogesterones; Male; Mice; Mice, Inbred C57BL; NADP; Pregnenolone; Progesterone; Testis; Testosterone | 1977 |
A biphasic response of testicular 17beta-hydroxysteroid oxidoreductase associated with advancing age in heat-acclimatized mouse.
Topics: Acclimatization; Aging; Androstenediols; Androstenedione; Animals; Body Weight; Dehydroepiandrosterone; Estrogens; Hot Temperature; Hydroxysteroid Dehydrogenases; Male; Mice; Mice, Inbred C57BL; NADP; Organ Size; Testis; Testosterone | 1977 |
Histochemistry of 11-beta-hydroxysteroid dehydrogenase in rat submandibular gland. Effect of cortisol stimulation.
Topics: Alcohol Oxidoreductases; Alkaline Phosphatase; Androstenedione; Animals; Dimethyl Sulfoxide; Female; Formamides; Formazans; Hydrocortisone; Hydroxysteroid Dehydrogenases; NAD; NADP; Nitroblue Tetrazolium; Oxidoreductases; Phenanthrolines; Rats; Submandibular Gland; Tetrazolium Salts | 1977 |
Studies of the human testis. VIII. Product activation of 17beta-hydroxysteroid oxidoreductase for testosterone.
Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Androstenedione; Enzyme Activation; Humans; In Vitro Techniques; Male; Microsomes; Middle Aged; NADP; Testis; Testosterone | 1977 |
Aromatization of steroids by mitochondrial preparations from human term placenta.
Topics: Androstenedione; Aromatase; Calcium; Cholesterol; Estrogens; Female; Humans; Microsomes; Mitochondria; Mixed Function Oxygenases; NADP; Oxidoreductases; Placenta; Pregnancy | 1978 |
Further in vitro steroid metabolic studies of testicular 17beta-reduction deficiency.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Androstenediol; Androstenedione; Dehydroepiandrosterone; Disorders of Sex Development; Estradiol; Estrone; Humans; Male; Middle Aged; NAD; NADP; Testis; Testosterone | 1978 |
Effect of progestins on androgen delta4-3-ketosteroid-5alpha-A-ring reductase system in rat oral mucosa.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Kinetics; Medroxyprogesterone; Microsomes; Mouth Mucosa; NAD; NADP; Oxidoreductases; Rats; Testosterone | 1978 |
In vitro and in vivo studies on Leydig cell function in old rats.
Topics: Age Factors; Androstenedione; Animals; Bucladesine; Cell Count; Chorionic Gonadotropin; Hydroxyprogesterones; Leydig Cells; Luteinizing Hormone; Male; NADP; Organ Size; Pregnenolone; Progesterone; Rats; Receptors, Cell Surface; Testis; Testosterone | 1978 |
Comparative studies on the steroid metabolism in mammals. I. Characterization of 17 beta-hydroxysteroid dehydrogenase from monkey liver.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Dehydroepiandrosterone; Estrone; Haplorhini; Hydrogen-Ion Concentration; Kinetics; Liver; Macaca; Macaca mulatta; Male; NAD; NADP; Protein Denaturation; Substrate Specificity | 1978 |
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation.
Topics: Aminopyrine N-Demethylase; Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Male; Meperidine; Microsomes; Microsomes, Liver; NAD; NADP; Proadifen; Proteins; Rats | 1979 |
[Steroid-transforming enzymes from microorganisms. XI. Reversibility of the dehydrogenation reaction of the steroid-1-dehydrogenase from Nocardia opaca].
Topics: Androstadienes; Androstenedione; NAD; NADP; Nocardia; Oxidoreductases | 1979 |
Pathway from progesterone to 5alpha-reduced c19 steroids not involving androstenedione and testosterone in immature mouse testes in vitro.
Topics: Age Factors; Androstanes; Androstenedione; Androsterone; Animals; Chromatography, Paper; Hydroxyprogesterones; Hydroxysteroids; In Vitro Techniques; Male; Mice; NADP; Oxidation-Reduction; Pregnanediones; Progesterone; Testis; Testosterone | 1975 |
Aromatization of androgens by human abdominal and breast fat tissue.
Topics: Abdomen; Adipose Tissue; Androgens; Androstenedione; Androstenols; Axilla; Breast; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; In Vitro Techniques; NADP; Testosterone | 1975 |
Studies of the human testis. V. Properties of delta-5-3beta and 17beta-hydroxysteroid dehydrogenases in the biosynthesis of testosterone from dehydroepiandrosterone.
Topics: Aged; Alcohol Oxidoreductases; Androstenediols; Androstenedione; Catalysis; Cell-Free System; Dehydroepiandrosterone; Enzyme Inhibitors; Estradiol; Humans; Hydrogen-Ion Concentration; Hydroxysteroids; Kinetics; Male; Middle Aged; NAD; NADP; Sulfates; Testis; Testosterone; Tritium | 1975 |
Relationship between steroids and pyridine nucleotides in the oxido-reduction catalyzed by the 17 beta-hydroxysteroid dehydrogenase purified from the porcine testicular microsomal fraction.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Estrone; Hydroxysteroid Dehydrogenases; Kinetics; Male; Microsomes; NAD; NADP; Oxidation-Reduction; Structure-Activity Relationship; Swine; Testis; Testosterone; Time Factors | 1975 |
Subcellular localization and properties of mouse adrenal C19-steroid 5beta-reductase.
Topics: Adrenal Glands; Androstanes; Androstenedione; Animals; Hydroxysteroid Dehydrogenases; Mice; Mice, Inbred BALB C; NAD; NADP; Steroid Hydroxylases; Subcellular Fractions; Testosterone | 1975 |
Displacement of carbon monoxide from placental cytochrome P-450 by steroids: antagonistic effects of androstenedione and 19-norandrostenedione.
Topics: Androstenedione; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Estrenes; Female; Humans; Kinetics; Microsomes; NADP; Nandrolone; Oxidation-Reduction; Placenta; Pregnancy; Time Factors | 1975 |
Sodium periodate, sodium chloride, organic hydroperoxides, and H2O2 as hydroxylating agents in steroid hydroxylation reactions catalyzed by partially purified cytochrome P-450.
Topics: Androstenedione; Animals; Chlorine; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Periodic Acid; Peroxides; Phenobarbital; Rats; Steroid Hydroxylases | 1975 |
Studies on 17 beta-hydroxysteroid dehydrogenase in human endometrium and endometrial carcinoma. III. Partial purification and characterization of the microsomal enzyme.
Topics: Androstenedione; Endometrium; Estradiol; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Microsomes; NAD; NADP; Testosterone; Uterine Neoplasms | 1975 |
Time-dependent inhibition of human placental aromatase with a 2,19-methyleneoxy-bridged androstenedione.
Topics: Androstenedione; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Female; Humans; Kinetics; Molecular Structure; NADP; Placenta; Pregnancy; Protein Conformation | 1992 |
Comparison of the nuclear 5 alpha-reduction of testosterone and androstenedione in human prostatic carcinoma and benign prostatic hyperplasia.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Cell Fractionation; Cell Nucleus; Humans; Kinetics; Male; NADP; Oxidation-Reduction; Prostatic Hyperplasia; Prostatic Neoplasms; Testosterone | 1990 |
Delta 5-3 beta-hydroxysteroid dehydrogenase-isomerase activity in canine pancreas.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cell Nucleus; Cytosol; Dehydroepiandrosterone; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pancreas; Pregnenolone; Progesterone | 1990 |
7-substituted 1,4,6-androstatriene-3,17-diones as enzyme-activated irreversible inhibitors of aromatase.
Topics: Androstatrienes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding, Competitive; Cysteine; Enzyme Activation; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta | 1990 |
17 Beta-hydroxysteroid oxidoreductase activity: age-dependent profile in rat liver and kinetic properties of the hepatic microsomal enzyme in relation to cytochrome P450-dependent steroid hydroxylation.
Topics: 17-Hydroxysteroid Dehydrogenases; Age Factors; Aging; Androstenedione; Animals; Estradiol; Female; Hydrogen-Ion Concentration; Hydroxysteroids; Kinetics; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Sex Factors; Steroid 17-alpha-Hydroxylase; Testosterone | 1990 |
Purification of 5 beta-reductase from hepatic cytosol fraction of chicken.
Topics: Ammonium Sulfate; Androstenedione; Animals; Chickens; Chromatography; Cytosol; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Molecular Weight; NADP; Oxidoreductases; Progesterone; Testosterone | 1990 |
Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups.
Topics: Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Chemical Phenomena; Chemistry; Female; Gonadotropins, Equine; Imidazoles; Microsomes; Molecular Structure; NADP; Ovary; Pyrazoles; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship; Thiazoles; Triazoles; X-Ray Diffraction | 1990 |
Conversion of 19-oxo[2 beta-2H]androgens into oestrogens by human placental aromatase. An unexpected stereochemical outcome.
Topics: Androstenedione; Aromatase; Chemical Phenomena; Chemistry; Estrogens; Female; Humans; Hydroxytestosterones; Magnetic Resonance Spectroscopy; Microsomes; NADP; Placenta; Pregnancy; Stereoisomerism; Testosterone | 1990 |
Hydroxylation of 19-norandrostenedione by adrenal cortex mitochondrial P-450(11)beta.
Topics: Adrenal Cortex; Adrenodoxin; Androstenedione; Animals; Cattle; Chromatography, High Pressure Liquid; Ferredoxin-NADP Reductase; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Hydroxylation; Magnetic Resonance Spectroscopy; Mitochondria; Molecular Structure; NADP; Steroid 11-beta-Hydroxylase; Steroid Hydroxylases; Substrate Specificity | 1990 |
Cobalt-protoporphyrin, a synthetic heme analogue, feminizes hepatic androgen metabolism in the rat.
Topics: 5-alpha Reductase Inhibitors; Androgens; Androstenedione; Animals; Azasteroids; Dihydrotestosterone; Female; Growth Hormone; Hypophysectomy; Kinetics; Male; Microsomes, Liver; NADP; Porphyrins; Protoporphyrins; Pyridines; Rats; Rats, Inbred Strains; Testosterone | 1989 |
Enzymatic androgen assay: some properties of human placental microsomal aromatase.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Aromatase; Dehydroepiandrosterone; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Microsomes; NADP; Octoxynol; Oxidoreductases; Placenta; Polyethylene Glycols; Pregnancy; Solubility; Testosterone | 1985 |
Human liver microsomal steroid metabolism: identification of the major microsomal steroid hormone 6 beta-hydroxylase cytochrome P-450 enzyme.
Topics: Androstenedione; Animals; Cross Reactions; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Male; Microsomes, Liver; NADP; Progesterone; Rats; Steroid Hydroxylases; Substrate Specificity; Testosterone; Troleandomycin | 1988 |
Studies on steroid monooxygenase from Cylindrocarpon radicicola ATCC 11011. Oxygenative lactonization of androstenedione to testololactone.
Topics: Androstenedione; Hydrogen-Ion Concentration; Kinetics; Mitosporic Fungi; NADP; Oxidation-Reduction; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testolactone | 1986 |
Aromatisation of androstenedione by human breast cancer tissue: correlation with hormone receptor activity and possible biologic significance.
Topics: Androstenedione; Aromatase; Breast Neoplasms; Estrone; Female; Humans; In Vitro Techniques; Menopause; NADP; Neoplasm Metastasis; Receptors, Estrogen; Receptors, Progesterone | 1987 |
Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Female; Humans; Kinetics; Male; Microsomes, Liver; Molecular Conformation; NADP; Placenta; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
P-45011 beta-dependent conversion of cortisol to cortisone, and 19-hydroxyandrostenedione to 19-oxoandrostenedione.
Topics: Adrenal Glands; Adrenodoxin; Androstenedione; Animals; Cattle; Cortisone; Cytochrome P-450 Enzyme System; Ferredoxin-NADP Reductase; Gas Chromatography-Mass Spectrometry; Hydrocortisone; Isoenzymes; NADP; Rabbits | 1986 |
Stereochemistry of estrogen biosynthesis by a reconstituted aromatase cytochrome P-450 preparation from human placenta.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Cytochrome P-450 Enzyme System; Estrogens; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Microsomes; Molecular Conformation; NADP; Placenta; Pregnancy; Tritium | 1986 |
Age dependent changes in androgen metabolism in the rat prostate.
Topics: 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Age Factors; Androgens; Androstenedione; Animals; Dihydrotestosterone; Male; NAD; NADP; Prostate; Rats; Rats, Inbred Strains | 1985 |
Inactivation of human placental aromatase by 6 alpha- and 6 beta-hydroperoxyandrostenedione.
Topics: Androstenedione; Aromatase Inhibitors; Dithiothreitol; Female; Humans; Microsomes; NADP; Oxidoreductases; Placenta; Pregnancy; Time Factors | 1985 |
Oxygen dependence of oestrogen production by human placental microsomes and cultured choriocarcinoma cells.
Topics: Androstenedione; Aromatase; Cell Line; Choriocarcinoma; Estradiol; Estrogens; Estrone; Female; Humans; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Placenta; Pregnancy; Testosterone; Uterine Neoplasms | 1985 |
Androgen assimilation by normal and hyperplastic dog prostate glands.
Topics: Androstenedione; Androstenols; Animals; Binding, Competitive; Cell Membrane; Chromatography, Thin Layer; Dihydrotestosterone; Dogs; Estradiol; Histocytochemistry; In Vitro Techniques; Male; NADP; Progesterone; Prostate; Prostatic Hyperplasia; Stimulation, Chemical; Testosterone; Time Factors; Tritium | 1974 |
Inhibition studies on the aromatization of androst-4-ene-3,17-dione by human placental microsomal preparations.
Topics: 17-Ketosteroids; Androstenedione; Androstenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Estrone; Female; Humans; In Vitro Techniques; Microsomes; NADP; Oxygen Consumption; Placenta; Tritium | 1972 |
Differences between germ-free and conventional rats in liver microsomal metabolism of steroids.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androstanes; Androstenedione; Androstenes; Animals; Carbon Isotopes; Cholestenes; Cholesterol; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Germ-Free Life; Hydroxylation; Hydroxysteroids; Ketosteroids; Lithocholic Acid; Male; Microsomes, Liver; NADP; Pregnanes; Progesterone; Rats; Time Factors; Tritium | 1973 |
Sex dependency of steroid retention in rat-liver slices incubated with testosterone.
Topics: Androstenedione; Animals; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Cortisone; Culture Media; Female; Hydrogenation; Hydroxylation; Liver; Male; NADP; Oxidoreductases; Rats; Sex Factors; Steroid Hydroxylases; Testosterone | 1973 |
Studies on 17 -hydroxysteroid dehydrogenase in immature mouse ovarian tissue.
Topics: Androstenedione; Animals; Chromatography, Gas; Chromatography, Thin Layer; Crystallization; Estradiol; Female; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; Kinetics; Mass Spectrometry; Mice; NAD; NADP; Ovary; Tritium | 1973 |
The effect of androgenic hormones on the reduced nicotinamide adenine dinucleotide phosphate:delta-4-3-ketosteroid 5 alpha-oxidoreductase of rat ventral prostate.
Topics: Adrenal Glands; Adrenalectomy; Androstanes; Androstenedione; Androsterone; Animals; Castration; Dihydrotestosterone; Estradiol; Hypophysectomy; Ketosteroids; Male; NADP; Organ Size; Oxidoreductases; Parathyroid Glands; Pituitary Gland; Pregnanes; Progesterone; Prostate; Rats; Testis; Testosterone; Thyroxine; Time Factors; Tritium | 1973 |
The aromatization of (7 -3H) androstenedione by human placental mitochondria.
Topics: 17-Ketosteroids; Acetylation; Androgens; Androstenedione; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Estradiol; Estrone; Female; Humans; Hydrogen-Ion Concentration; Hydroxysteroids; Microsomes; Mitochondria; NAD; NADP; Oxidoreductases; Placenta; Pregnancy; Tritium; Ultracentrifugation | 1973 |
Metabolism of androst-4-ene-3,17-dione by subcellular fractions of rat adrenal tissue with particular reference to microsomal C19-steroid 5alpha-reductase.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Androstenedione; Animals; Chromatography, Thin Layer; Corticosterone; Dihydrotestosterone; Kinetics; Malates; Male; Microsomes; NADP; Oxidoreductases; Rats; Steroid Hydroxylases; Subcellular Fractions; Testosterone; Time Factors; Tritium | 1973 |
Testosterone metabolism in slices and subcellular fractions of human liver.
Topics: 17-Ketosteroids; Androgens; Androstanes; Androstenedione; Androsterone; Chromatography, Gas; Female; Humans; Hydroxysteroids; In Vitro Techniques; Liver; NAD; NADP; Sterols; Subcellular Fractions; Testosterone; Tritium | 1973 |
Enzymes of androgen metabolism in human leucocytes.
Topics: 17-Ketosteroids; Androgens; Androstanes; Androstenedione; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Leukocytes; Lymphocytes; NADP; Oxidoreductases; Testosterone | 1973 |
Metabolism of 3-beta-hydroxy-5-ene steroids by testes of rats acclimatized to a hot environment.
Topics: 17-alpha-Hydroxypregnenolone; 17-Hydroxycorticosteroids; Acclimatization; Androstanes; Androstenedione; Androstenes; Animals; Carbon Isotopes; Chromatography, Thin Layer; Cryptorchidism; Dehydroepiandrosterone; Hot Temperature; Hydroxyprogesterones; In Vitro Techniques; Male; NADP; Pregnenolone; Rats; Testis; Testosterone; Time Factors; Tissue Extracts | 1973 |
Steroid metabolism by mouse submaxillary glands. I. In vitro metabolism of testosterone and 4-androstene-3,17-dione.
Topics: Androstanes; Androstenedione; Androsterone; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Crystallization; Hydroxysteroids; Male; Mice; NADP; Oxidation-Reduction; Submandibular Gland; Testosterone; Time Factors; Tritium | 1973 |
In vitro steroidogenesis in feline testes.
Topics: Androstenedione; Androstenols; Animals; Carbon Radioisotopes; Castration; Cats; Chromatography, Thin Layer; Cytosol; Dehydroepiandrosterone; Hydrocortisone; Hydroxyprogesterones; Male; Microsomes; NAD; NADP; Oxidation-Reduction; Pregnenolone; Progesterone; Testis; Testosterone; Time Factors | 1973 |
In vitro biosynthesis of androgens in canine testes.
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Carbon Radioisotopes; Cytosol; Dehydroepiandrosterone; Dogs; Hydroxyprogesterones; In Vitro Techniques; Male; Microsomes; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Stimulation, Chemical; Testis; Testosterone; Time Factors | 1973 |
In vitro on an HCG responsive, testosterone secreting adrenal cortical adenoma.
Topics: Acetates; Adenoma; Adenosine Triphosphate; Adrenal Gland Neoplasms; Androstenedione; Carbon Radioisotopes; Chorionic Gonadotropin; Coenzymes; Dehydroepiandrosterone; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Mitochondria; NAD; NADP; Pregnenolone; Progesterone; Radioimmunoassay; Subcellular Fractions; Testosterone; Tritium | 1973 |
[Partial characterization of a delta 4-3-ketosteroid-5-oxidoreductase in seminal vesicles of the anuran amphibian Discoglossus pictus].
Topics: Amphibians; Androstanes; Androstenedione; Animals; Cell Fractionation; Cell Nucleus; Chromatography, Paper; Chromatography, Thin Layer; Cytosol; Hydrogen-Ion Concentration; Hydroxysteroids; Ketosteroids; Kinetics; Male; Microsomes; Mitochondria; NADP; Oxidoreductases; Seminal Vesicles; Temperature; Testosterone | 1973 |
Kinetic studies on the enzymes catalysing the conversion of 17alpha-hydroxyprogesterone and dehydroepiandrosterone to androstenedione in the human adrenal gland in vitro.
Topics: 17-alpha-Hydroxypregnenolone; Adrenal Glands; Androstenedione; Dehydroepiandrosterone; Depression, Chemical; Estradiol; Estrone; Female; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; NAD; NADP; Oxidoreductases; Pregnenolone; Progesterone | 1974 |
Liver microsomal hydroxylation of steroid hormones after establishing an indigenous microflora in germfree rats.
Topics: Androstanes; Androstenedione; Animals; Autoradiography; Carbon Radioisotopes; Chromatography, Gas; Germ-Free Life; Hydroxylation; Intestines; Male; Mass Spectrometry; Microsomes, Liver; Mixed Function Oxygenases; NADP; Proteins; Rats | 1974 |
Formation of dihydrotestosterone and other 5 alpha-reduced metabolites by isolated seminiferous tubules and suspension of interstitial cells in a human testis.
Topics: Adolescent; Androstanes; Androstenedione; Carbon Isotopes; Chromatography, Paper; Dihydrotestosterone; Humans; In Vitro Techniques; Male; NADP; Pregnenolone; Sulfates; Testis; Tritium | 1973 |
Characteristics of the nuclear and microsomal steroid delta-4-5 alpha-hydrogenase of the rat prostate.
Topics: Androstenedione; Androstenes; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Thin Layer; Corticosterone; Dehydroepiandrosterone; Hydrogen-Ion Concentration; Hydroxyprogesterones; Male; Microsomes; Microsomes, Liver; NADP; Oxidoreductases; Pregnenolone; Progesterone; Prostate; Temperature; Testosterone; Tritium | 1974 |
Evidence of the direct aromatization of testosterone and different aromatization sites for testosterone and androstenedione in human placental microsomes.
Topics: 17-Hydroxycorticosteroids; Androstenedione; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Crystallization; Estradiol; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Kinetics; Microsomes; Models, Chemical; Multienzyme Complexes; NADP; Oxidoreductases; Placenta; Pregnancy; Sodium Chloride; Testosterone; Tritium | 1974 |
Effects of a synthetic estrogen upon steroid bioconversion in vitro in testes of patients with prostatic cancer.
Topics: 17-alpha-Hydroxypregnenolone; Administration, Oral; Aged; Androstenedione; Enzyme Repression; Hexestrol; Humans; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Isomerases; Lyases; Male; Middle Aged; Mixed Function Oxygenases; NADP; Progesterone; Prostatic Neoplasms; Spermatogenesis; Steroids; Testis; Testosterone | 1974 |
Studies on enzyme reactions related to steroid biosynthesis. 3. Distribution of the testicular enzymes related to androgen production between the seminiferous tubules and interstitial tissue.
Topics: Androstenedione; Androstenes; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hydroxysteroids; Lyases; Male; NADP; Oxidation-Reduction; Oxidoreductases; Pregnenes; Progesterone; Rats; Steroid Hydroxylases; Testis; Testosterone | 1974 |
Utilization of oxygen and reduced nicotinamide adenine dinucleotide phosphate by human placental microsomes during aromatization of androstenedione.
Topics: Androstenedione; Androstenols; Chromatography; Chromatography, Thin Layer; Cyanides; Estradiol; Estrone; Female; Humans; Hydroxylation; Kinetics; Microsomes; NADP; Oxidation-Reduction; Oxygen Consumption; Placenta; Pregnancy; Silicon Dioxide; Steroids; Time Factors; Tritium | 1974 |
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors | 1974 |
Testosterone formation in testis of the immature androgen insensitive pseudohermaphrodite male rat (Stanley-Gumbreck rat).
Topics: Androgens; Androstenedione; Androstenols; Androsterone; Animals; Carbon Radioisotopes; Chromatography; Crystallization; Disorders of Sex Development; Glucosephosphate Dehydrogenase; In Vitro Techniques; Male; NADP; Oxidation-Reduction; Pregnenolone; Progesterone; Rats; Rats, Inbred Strains; Testis; Testosterone; Time Factors; Tritium | 1974 |
Metabolism of testosterone and 5alpha-dihydrotestosterone in vitro by the seminiferous tubules of the mature rat.
Topics: Androstenediols; Androstenedione; Animals; Chromatography, Paper; Dihydrotestosterone; In Vitro Techniques; Male; NAD; NADP; Oxidation-Reduction; Radioisotope Dilution Technique; Rats; Testis; Testosterone; Time Factors; Tritium | 1974 |
[Sexually differentiated and sexually undifferentiated 3alpha- and 3beta-hydroxysteroid dehydrogenase activities and their intracellular localization in rat liver].
Topics: Androstanes; Androstenedione; Animals; Carbon Radioisotopes; Chromatography, Paper; Cytosol; Female; Hydroxysteroid Dehydrogenases; Liver; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats; Sex Factors; Subcellular Fractions | 1973 |
[Hydroxysteroid oxidoreductases and their function as catalysts of specific hydrogen transfer between steroid hormones in human placenta. II. Kinetic studies and hydrogen transfer between C-17 of estradiol-17 beta and C-20 or progesterone].
Topics: Androstenedione; Carbon Radioisotopes; Chromatography, Gel; Coenzymes; Cytochrome c Group; Estradiol; Female; Humans; Hydrogen; Hydrogen-Ion Concentration; Hydroxysteroid Dehydrogenases; In Vitro Techniques; Kinetics; Metals; Molecular Weight; NAD; NADP; Phospholipids; Placenta; Pregnancy; Progesterone; Proteins; Sulfhydryl Reagents; Temperature; Testosterone; Time Factors; Tritium | 1974 |
The flux of intermediates and products in aromatizaton of C19 steroids by human placental microsomes.
Topics: Androstenedione; Androstenols; Biotransformation; Carbon Radioisotopes; Deuterium; Estradiol; Estrone; Female; Humans; Hydroxysteroid Dehydrogenases; Microsomes; NADP; Placenta; Pregnancy; Temperature; Testosterone; Time Factors | 1974 |
Studies on the aromatization of C-19 androgens.
Topics: Androgens; Androstenedione; Cytochrome P-450 Enzyme System; Estrone; Female; Humans; Microsomes; NADP; Oxidation-Reduction; Oxygen Consumption; Placenta; Testosterone | 1973 |
Steroidogenesis in vitro by the ovarian tissue of the domestic fowl (Gallus domesticus).
Topics: 17-alpha-Hydroxypregnenolone; Androstenedione; Animals; Autoradiography; Carbon Radioisotopes; Chickens; Chromatography, Thin Layer; Dehydroepiandrosterone; Estradiol; Estrone; Female; Hydroxyprogesterones; In Vitro Techniques; NAD; NADP; Ovary; Pregnenolone; Progesterone; Steroids; Testosterone; Time Factors; Tritium | 1974 |
Human skin androgen metabolism and preliminary evidence for its control by two forms of 17 beta-hydroxysteroid oxidoreductase.
Topics: 17-Hydroxysteroid Dehydrogenases; Adult; Age Factors; Aged; Androstenedione; Axilla; Child; Female; Forehead; Humans; In Vitro Techniques; Male; Middle Aged; NAD; NADP; Skin; Testosterone | 1982 |
Human ovarian 17 beta-hydroxysteroid oxidoreductase activity: a comparison of normal and polycystic ovarian tissues.
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Androstenedione; Corpus Luteum; Female; Humans; Menstruation; NAD; NADP; Ovary; Polycystic Ovary Syndrome; Testosterone; Veins | 1983 |
Steroid metabolism in the rat visceral yolk sac during pregnancy.
Topics: Androstenedione; Animals; Dehydroepiandrosterone; Estradiol; Female; Gestational Age; Gonadal Steroid Hormones; NAD; NADP; Pregnancy; Pregnancy, Animal; Progesterone; Progestins; Rats; Testosterone; Yolk Sac | 1982 |
Hydroperoxides as inactivators of aromatase: 10 beta-hydroperoxy-4-estrene-3,17-dione, crystal structure and inactivation characteristics.
Topics: Androstenedione; Aromatase Inhibitors; Benzene Derivatives; Binding, Competitive; Chemical Phenomena; Chemistry; Estrenes; Female; Heme; Humans; Hydrogen Peroxide; Kinetics; Microsomes; NADP; Oxidoreductases; Placenta; Pregnancy; X-Ray Diffraction | 1984 |
De novo biosynthesis of 6 beta-hydroperoxyandrostenedione in human placental microsomes.
Topics: Androstenedione; Carbon Monoxide; Chromatography, High Pressure Liquid; Female; Humans; Hydroxymercuribenzoates; Kinetics; Microsomes; NADP; Oxygen; Placenta; Pregnancy | 1984 |
Estrogen synthetase. Effect of sulfhydryl reactive reagents on androgen aromatization by human term placental microsomes.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Microsomes; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases; Placenta; Pregnancy; Rabbits; Rats; Sulfhydryl Reagents | 1980 |
Amino acid composition and immunochemical properties of porcine testicular 17 beta-hydroxysteroid dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Amino Acids; Androstenedione; Animals; Binding Sites; Isoelectric Point; Male; Molecular Weight; NADP; Swine; Testis | 1980 |
17 beta-Oxidation of estradiol and testosterone in the human testis.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Estradiol; Estrone; Humans; In Vitro Techniques; Kinetics; Male; NADP; Oxidation-Reduction; Testis; Testosterone | 1982 |
Kinetic mechanism of porcine testicular 17 beta-hydroxysteroid dehydrogenase.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Kinetics; Male; NADP; Oxidation-Reduction; Spectrometry, Fluorescence; Swine; Testis; Testosterone | 1982 |
C19-steroid 5 beta-reductase and 3- and 17-oxidoreductases of adult male hamster kidney.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Cricetinae; Cytosol; Hydrogen-Ion Concentration; Kidney; Male; Mass Spectrometry; Microsomes; NADP; Oxidoreductases; Testosterone | 1982 |
17 alpha and 17 beta-oxidoreductases of adult female hamster liver and kidney.
Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstenedione; Animals; Cricetinae; Female; Hydrogen-Ion Concentration; Kidney; Liver; NADP; Testosterone | 1982 |
17-Hydroxyprogesterone metabolism in the monkey fetal adrenal: C17-20lyase and 21-hydroxylase activities.
Topics: Adrenal Glands; Aldehyde-Lyases; Androstenedione; Animals; Female; Hydroxyprogesterones; Kinetics; Macaca; Macaca mulatta; NADP; Pregnancy; Steroid 17-alpha-Hydroxylase; Steroid 21-Hydroxylase; Steroid Hydroxylases | 1981 |
[In vitro aromatization of androgens in the presence of testosterone binding proteins from human placenta or serum].
Topics: Androstenedione; Estradiol; Estrone; Female; Humans; Microsomes; NADP; Placenta; Pregnancy; Sex Hormone-Binding Globulin; Testosterone | 1980 |
Ascorbic acid inhibition of aromatase activity in human placenta tissue.
Topics: Androstenedione; Aromatase Inhibitors; Ascorbic Acid; Female; Humans; Hydrogen-Ion Concentration; Microsomes; NADP; Oxidoreductases; Oxygen Consumption; Placenta; Pregnancy | 1981 |
NADPH: 4-ene-3-oxosteroid-5 alpha-reductase and NADH: 4-ene-3-oxosteroid-5 alpha-reductase in liver microsomes of different species of animals.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Cattle; Chickens; Chinchilla; Cricetinae; Dogs; Female; Guinea Pigs; Hydrogen-Ion Concentration; Male; Mesocricetus; Mice; Microsomes, Liver; NAD; NADP; Oxidoreductases; Rabbits; Rats; Sex Factors; Species Specificity; Swine | 1981 |
Quantitative requirements for NADPH in the support of aromatization by human placental microsomes.
Topics: Androstenedione; Aromatase; Female; Glucosephosphate Dehydrogenase; Humans; Kinetics; Microsomes; NADP; Oxidoreductases; Placenta; Pregnancy | 1981 |
Cooperative interaction of reduced pyridine nucleotides with estrogen synthetase of human placental microsomes.
Topics: Androstenedione; Aromatase; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Estradiol; Estrone; Female; Humans; Kinetics; Microsomes; NAD; NADP; Oxidoreductases; Placenta; Pregnancy | 1981 |
Kinetic studies of cytochrome P-45017 alpha, lyase dependent androstenedione formation from progesterone.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Glands; Aldehyde-Lyases; Androstenedione; Animals; Cytochrome P-450 Enzyme System; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyprogesterones; Kinetics; Models, Chemical; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxidoreductases; Progesterone; Steroid 17-alpha-Hydroxylase | 1995 |
Steroid metabolism by rabbit olfactory-specific P450 2G1.
Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Dihydrotestosterone; Estradiol; Female; Ketoconazole; Kinetics; Male; NADP; Olfactory Mucosa; Progesterone; Rabbits; Steroids; Substrate Specificity; Testosterone | 1994 |
Androgen metabolism in the different lobes of the prostate gland of intact, gonadectomized or hypophysectomized rats with or without androgen substitution.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Androstenedione; Animals; Hypophysectomy; Male; NAD; NADP; Orchiectomy; Organ Size; Prostate; Rats; Rats, Wistar; Testosterone | 1994 |
Inhibition and inactivation of constitutive cytochromes P450 in rat liver by parathion.
Topics: Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Hydroxylation; Immunoblotting; Male; Microsomes, Liver; NADP; Parathion; Progesterone; Rats; Rats, Wistar; Steroid 16-alpha-Hydroxylase | 1993 |
Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group.
Topics: Alkylation; Androstadienes; Androstenedione; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Female; Humans; Kinetics; Microsomes; Models, Molecular; Molecular Conformation; Molecular Structure; NADP; Placenta; Structure-Activity Relationship; Tritium | 1996 |
11 beta-hydroxylase activity in recombinant yeast mitochondria. In vivo conversion of 11-deoxycortisol to hydrocortisone.
Topics: Adrenodoxin; Androstenedione; Base Sequence; Cloning, Molecular; Corticosterone; Cortodoxone; Desoxycorticosterone; DNA Primers; Electron Transport Complex IV; Escherichia coli; Ferredoxin-NADP Reductase; Gene Expression; Hydrocortisone; Hydroxylation; Mitochondria; Molecular Sequence Data; NADP; Recombinant Proteins; Saccharomyces cerevisiae; Steroid 11-beta-Hydroxylase | 1996 |
Nitric oxide inhibits aromatase activity: mechanisms of action.
Topics: Androstenedione; Aromatase Inhibitors; Carbon Monoxide; Cells, Cultured; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Female; Gene Expression Regulation, Enzymologic; Granulosa Cells; Humans; Luteal Cells; Mercaptoethanol; Microsomes; NADP; Nitric Oxide; Penicillamine; Placenta; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Reagents | 1996 |
Novel 19-(cyclopropylamino)-androst-4-en-3,17-dione: a mechanism-based inhibitor of aromatase.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Cyclopropanes; Enzyme Inhibitors; Enzyme Stability; Estradiol; Humans; Kinetics; Magnetic Resonance Spectroscopy; Microsomes; Molecular Structure; NADP; Placenta; Steroids; Testosterone | 1996 |
Optimization of a classical aromatase activity assay and application in normal, adenomatous and malignant breast parenchyma.
Topics: Adenoma; Androstenedione; Aromatase; Breast; Breast Neoplasms; Carcinoma; Estradiol; Estrone; Female; Humans; Kinetics; NADP; Placenta; Postmenopause; Premenopause; Sensitivity and Specificity; Testosterone | 1996 |
Aromatase inactivation by a suicide substrate, androst-5-ene-4,7,17-trione: the 5beta,6beta-epoxy-19-oxo derivative, as a possible reactive electrophile irreversibly binding to the active site.
Topics: Acetylcysteine; Androstanes; Androstenedione; Androstenes; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Cysteine; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta; Pregnancy | 1997 |
Studies directed toward a mechanistic evaluation of aromatase inhibition by androst-5-ene-7,17-dione. Time-dependent inactivation by the 19-nor and 5 beta, 6 beta-epoxy derivatives.
Topics: Androstanes; Androstenedione; Aromatase; Aromatase Inhibitors; Binding, Competitive; Enzyme Inhibitors; Female; Humans; Kinetics; NADP; Placenta; Pregnancy; Structure-Activity Relationship; Time Factors | 1997 |
Novel connections between NADPH-induced lipid peroxidation and cytochrome P450 inactivation, and antioxidant and enzyme protective properties of estradiol in gonadal membranes.
Topics: Androstenedione; Animals; Antioxidants; Chorionic Gonadotropin; Down-Regulation; Enzyme Inhibitors; Estradiol; Humans; Iron; Lipid Peroxides; Male; Malondialdehyde; Microsomes; NADP; Progesterone; Rats; Rats, Wistar; Steroid 17-alpha-Hydroxylase; Testis | 1997 |
Studies of the time-dependent inactivation of aromatase by 4beta,5beta-epoxy-6-one and 5beta,6beta-epoxy-4-one steroids under various conditions.
Topics: Androstenedione; Aromatase Inhibitors; Cysteine; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; NADP; Placenta; Pregnancy; Stereoisomerism; Steroids; Time Factors | 1999 |
Expression of the 17beta-hydroxysteroid dehydrogenase type 5 mRNA in the human brain.
Topics: 17-Hydroxysteroid Dehydrogenases; Adolescent; Adult; Aged; Androstenedione; Brain; Cerebral Cortex; Child; Child, Preschool; Female; Gene Expression; Humans; Infant; Isoenzymes; Male; Middle Aged; NADP; RNA, Messenger; Sex Characteristics; Temporal Lobe; Testosterone; Tissue Distribution | 2001 |
17Beta-hydroxysteroid dehydrogenase from Cochliobolus lunatus: model structure and substrate specificity.
Topics: 17-Hydroxysteroid Dehydrogenases; Amino Acid Sequence; Androgens; Androstenedione; Ascomycota; Binding Sites; Estrogens; Kinetics; Magnaporthe; Models, Molecular; Molecular Sequence Data; NADP; Protein Subunits; Sequence Homology, Amino Acid; Substrate Specificity | 2000 |
Inhibition of human cytochrome P450 aromatase activity by butyltins.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Microsomes; NADP; Organotin Compounds; Placenta; Pregnancy | 2001 |
Time-dependent aromatase inactivation by 4 beta,5 beta-epoxides of the natural substrate androstenedione and its 19-oxygenated analogs.
Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Binding, Competitive; Enzyme Inhibitors; Epoxy Compounds; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Microsomes; NADP; Placenta; Pregnancy; Substrate Specificity | 2002 |
Intestinal and hepatic microsomal metabolism of testosterone and progesterone by a 3 alpha-hydroxysteroid dehydrogenase to the 3 alpha-hydroxy derivatives in the channel catfish, Ictalurus punctatus.
Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cytosol; Dihydrotestosterone; Hydroxytestosterones; Ictaluridae; Intestinal Mucosa; Mass Spectrometry; Microsomes, Liver; NADP; Progesterone; Testosterone | 2002 |
Metabolism of estrogens and androgens by scleractinian corals.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androgens; Androstenedione; Animals; Anthozoa; Dinoflagellida; Estradiol; Estrogens; Estrone; Isotope Labeling; NADP; Testosterone | 2003 |
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Androgens; Androstenedione; Binding Sites; Crystallography, X-Ray; Humans; Hydroxyprostaglandin Dehydrogenases; Male; Models, Molecular; NADP; Phenylalanine; Prostate; Protein Conformation; Testosterone | 2004 |
Androgen secretion by Rcho-1 cells is independent of extracellular glutamate concentration.
Topics: Androstenedione; Animals; Cell Differentiation; Choriocarcinoma; Culture Media; Female; Glutamic Acid; Glutaminase; NADP; Placenta; Progesterone; Rats; Transaminases; Tumor Cells, Cultured | 2004 |
Extracellular 3beta-hydroxysteroid oxidase of Mycobacterium vaccae VKM Ac-1815D.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Cell Wall; Cell-Free System; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dehydroepiandrosterone; Electrophoresis, Polyacrylamide Gel; Glycerol; Hydrogen; Hydroxysteroid Dehydrogenases; Kinetics; Mass Spectrometry; Models, Chemical; Mycobacterium; NAD; NADP; Oxidoreductases; Sitosterols; Steroids; Testosterone | 2004 |
Comparative inhibition of inducible and constitutive CYPs in rat hepatic microsomes by parathion.
Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Insecticides; Kinetics; Male; Microsomes, Liver; NADP; Parathion; Rats; Rats, Wistar | 2004 |
Steroid 5alpha-reductase activity of Treponema denticola.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Buffers; Carbon Radioisotopes; Cholestanol; Cholesterol; Chromatography, Thin Layer; Coenzymes; Corticosterone; Enzyme Inhibitors; Ethanol; Humans; Hydrogen-Ion Concentration; NADP; Progesterone; Radiopharmaceuticals; Subcellular Fractions; Substrate Specificity; Testosterone; Time Factors; Treponema denticola | 2007 |
Role of 11β-OH-C(19) and C(21) steroids in the coupling of 11β-HSD1 and 17β-HSD3 in regulation of testosterone biosynthesis in rat Leydig cells.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Corticosterone; Leydig Cells; Male; NADP; Oxidation-Reduction; Protein Transport; Rats; Rats, Sprague-Dawley; Steroids; Testosterone | 2011 |