androstenedione has been researched along with ketoconazole in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (38.89) | 18.7374 |
| 1990's | 12 (33.33) | 18.2507 |
| 2000's | 4 (11.11) | 29.6817 |
| 2010's | 6 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cole, PA; Robinson, CH | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Agard, H; Amato, E; Bankemper, T; Bonfield, K; Keeler, JM; Ma, L; McCallum, A; Paula, S; Roy, D; Steller, J | 1 |
| Akaike, M; Hirai, M; Kumai, T; Masubuchi, Y; Tanaka, M; Watanabe, M | 1 |
| Adelmann, B; Engelhardt, D; Weber, MM; Will, A | 1 |
| Biason, A; Boscaro, M; Mantero, F; Scaroni, C; Sonino, N | 1 |
| Conget, JI; Ferrer, J; González-Clemente, JM; Halperin, I; Martinez-Osaba, MJ; Vilardell, E | 1 |
| Ayub, M; Levell, MJ | 2 |
| Bhansali, A; Dash, RJ; Khandekar, S; Lata, V | 2 |
| Cummings, KB; Havlin, KH; Jordan, VC; Lange, PH; Messing, EM; Trump, DL | 1 |
| Armstrong, DT; Glasier, MA; Khalil, MW; Lang, T; Morley, P | 1 |
| Al-Sarraf, M; Decker, DA; Kresge, C; Subramanian, MG; Tapazoglou, E | 1 |
| Amery, W; Beerens, D; Caers, I; Coene, MC; De Coster, R; Haelterman, C | 1 |
| Trachtenberg, J; Zadra, J | 1 |
| Aste, N; Lecca, U; Marcello, C; Medda, F; Parodo, G; Pascalis, P; Pia, G; Puligheddu, P | 1 |
| Cantwell, BM; Dowsett, M; Harris, AL | 1 |
| Estabrook, RW; Mason, JI; Sheets, JJ; Wise, CA | 1 |
| Allen, J; Bloom, SR; Doble, A; Dunlop, H; Kerle, DJ; Smith, C; Ware, H; Williams, G; Yeo, T | 1 |
| Chaban, M; Denis, L; Mahler, C | 1 |
| Bochra, C; Feldman, D; Loose, DS; Pont, A; Reitz, RE; Stevens, DA; Williams, PL | 1 |
| Brugmans, J; DeCoster, R; Santen, RJ; Symoens, J; Van den Bossche, H | 1 |
| Trachtenberg, J | 1 |
| Coon, MJ; Ding, X | 1 |
| Bhatnagar, AS; King, EJ; Purba, HS; Richert, P | 1 |
| Moslemi, S; Seralini, GE | 1 |
| Akaza, H; Fujikura, T; Ideyama, Y; Ishikawa, H; Kudoh, M; Nakahara, T; Nanya, T; Shikama, H; Susaki, Y; Tanimoto, K | 1 |
| Iranmanesh, A; Mulligan, T; Veldhuis, JD; Zwart, A | 1 |
| Blázquez, M; Dimastrogiovanni, G; Fernandes, D; Porte, C | 1 |
| Amory, JK; Anawalt, BD; Bremner, WJ; Lin, K; Marck, BT; Matsumoto, AM; Nya-Ngatchou, JJ; Page, ST; Roth, MY | 1 |
| Panter, GH; Thorpe, KL; Weltje, L; Wheeler, JR | 1 |
| Aceves-Ramos, A; Gaona, B; Romano, MC; Valdez, RA; Willms, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
2 review(s) available for androstenedione and ketoconazole
| Article | Year |
|---|---|
Mechanism and inhibition of cytochrome P-450 aromatase.
Topics: Affinity Labels; Aromatase; Aromatase Inhibitors; Binding, Competitive; Humans; Molecular Structure; Photochemistry | 1990 |
Test concentration setting for fish in vivo endocrine screening assays.
Topics: Androstenedione; Animals; Endocrine Disruptors; Ethylene Glycols; Fishes; Flutamide; Imidazoles; Ketoconazole; Maximum Tolerated Dose; Octanols; Phenols; Potassium Permanganate; Sodium Dodecyl Sulfate | 2013 |
2 trial(s) available for androstenedione and ketoconazole
| Article | Year |
|---|---|
Site of action of low dose ketoconazole on androgen biosynthesis in men.
Topics: Adult; Aldehyde-Lyases; Androgens; Androstenedione; Cytochrome P-450 Enzyme System; Humans; Hydroxyprogesterones; Imidazoles; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Piperazines; Steroid 17-alpha-Hydroxylase; Testosterone | 1983 |
Androgen synthesis in the gonadotropin-suppressed human testes can be markedly suppressed by ketoconazole.
Topics: 14-alpha Demethylase Inhibitors; 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androgens; Androstenedione; Contraception; Dehydroepiandrosterone; Drug Design; Drug Synergism; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Male; Middle Aged; Oligopeptides; Placebos; Spermatogenesis; Testis; Testosterone; Young Adult | 2013 |
32 other study(ies) available for androstenedione and ketoconazole
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Development of a new class of aromatase inhibitors: design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives.
Topics: Aromatase; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Isoflavones; Molecular Structure; Structure-Activity Relationship | 2012 |
Disturbance or relatively important actions of antihypertensives, antifungal agent and opiate antagonist to the testicular steroidogenesis in rat.
Topics: Androstenedione; Animals; Antifungal Agents; Antihypertensive Agents; Clonidine; Estradiol; Ketoconazole; Male; Naloxone; Narcotic Antagonists; Prazosin; Rats; Testis; Testosterone; Verapamil | 1992 |
Effect of ketoconazole on human ovarian C17,20-desmolase and aromatase.
Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androstenedione; Aromatase; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Female; Granulosa Cells; Humans; Hydroxyprogesterones; Ketoconazole; Ovary; Steroid 17-alpha-Hydroxylase | 1991 |
Low-dose ketoconazole treatment in hirsute women.
Topics: Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Drug Evaluation; Estradiol; Female; Follicle Stimulating Hormone; Hair; Hirsutism; Humans; Ketoconazole; Luteinizing Hormone; Prolactin; Testosterone | 1990 |
Evaluation of clinical and hormonal effects in hirsute women treated with ketoconazole.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Hirsutism; Humans; Hydroxyprogesterones; Ketoconazole; Testosterone | 1990 |
The inhibition of human prostatic aromatase activity by imidazole drugs including ketoconazole and 4-hydroxyandrostenedione.
Topics: Androstenedione; Aromatase Inhibitors; Estradiol; Estrone; Humans; Imidazoles; Ketoconazole; Male; Prostate; Structure-Activity Relationship | 1990 |
Ketoconazole in the treatment of Cushing's disease.
Topics: 17-alpha-Hydroxyprogesterone; Adolescent; Adult; Androstenedione; Cushing Syndrome; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Middle Aged; Testosterone; Time Factors | 1990 |
Circulating cortisol & related steroids following ketoconazole challenge in Cushing's disease.
Topics: 17-alpha-Hydroxyprogesterone; Aldehyde-Lyases; Androstenedione; Cushing Syndrome; Cytochrome P-450 Enzyme Inhibitors; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase | 1990 |
High-dose ketoconazole in advanced hormone-refractory prostate cancer: endocrinologic and clinical effects.
Topics: Acid Phosphatase; Aged; Aged, 80 and over; Androstenedione; Antigens, Neoplasm; Biomarkers, Tumor; Diethylstilbestrol; Drug Evaluation; Humans; Hydrocortisone; Ketoconazole; Male; Middle Aged; Orchiectomy; Pituitary Hormone-Releasing Hormones; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Testicular Hormones; Testosterone | 1989 |
Formation of 4-oestrene-3,17-dione (19-norandrostenedione) by porcine granulosa cells in vitro is inhibited by the aromatase inhibitor 4-hydroxyandrostenedione and the cytochrome P-450 inhibitors aminoglutethimide phosphate and ketoconazole.
Topics: Aminoglutethimide; Androstenedione; Animals; Cells, Cultured; Female; Granulosa Cells; Ketoconazole; Swine | 1989 |
High-dose ketoconazole therapy in patients with metastatic prostate cancer.
Topics: Adenocarcinoma; Aged; Androstenedione; Combined Modality Therapy; Dehydroepiandrosterone; Dexamethasone; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Humans; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Neoplasm Metastasis; Orchiectomy; Prostatic Neoplasms; Testosterone | 1986 |
Effects of high dose ketoconazole therapy on the main plasma testicular and adrenal steroids in previously untreated prostatic cancer patients.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex Hormones; Aged; Androgens; Androstenedione; Corticosterone; Cortodoxone; Dehydroepiandrosterone; Desoxycorticosterone; Humans; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Testosterone | 1986 |
Steroid synthesis inhibition by ketoconazole: sites of action.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aldehyde-Lyases; Androgens; Androstenedione; Chorionic Gonadotropin; Cosyntropin; Cytochrome P-450 Enzyme Inhibitors; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Male; Progesterone; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Testosterone | 1988 |
Short term treatment with ketoconazole: effects on gonadal and adrenal steroidogenesis in women.
Topics: 17-alpha-Hydroxyprogesterone; Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Hydroxyprogesterones; Ketoconazole; Luteinizing Hormone; Radioimmunoassay; Testosterone | 1987 |
High dose ketoconazole: endocrine and therapeutic effects in postmenopausal breast cancer.
Topics: 17-alpha-Hydroxyprogesterone; Aged; Aged, 80 and over; Androstenedione; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Ketoconazole; Menopause; Middle Aged; Sex Hormone-Binding Globulin; Testosterone | 1988 |
Structure-activity relationships of the inhibition of human placental aromatase by imidazole drugs including ketoconazole.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Humans; Imidazoles; Ketoconazole; Microsomes; Placenta; Structure-Activity Relationship | 1988 |
Inhibition of rat liver microsomal cytochrome P-450 steroid hydroxylase reactions by imidazole antimycotic agents.
Topics: Androstenedione; Animals; Antifungal Agents; Chromatography, High Pressure Liquid; Clotrimazole; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Imidazoles; Ketoconazole; Male; Miconazole; Microsomes, Liver; Rats; Steroid Hydroxylases | 1986 |
Objective responses to ketoconazole therapy in patients with relapsed progressive prostatic cancer.
Topics: Acid Phosphatase; Aged; Androstenedione; Humans; Ketoconazole; Male; Middle Aged; Prostatic Neoplasms; Testosterone; Time Factors | 1986 |
Clinical applications of ketoconazole in prostatic cancer.
Topics: Androstenedione; Humans; Ketoconazole; Male; Prostatic Neoplasms; Testosterone | 1985 |
Ketoconazole blocks adrenal steroid synthesis.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androstenedione; Animals; Antifungal Agents; Dehydroepiandrosterone; Dose-Response Relationship, Drug; Humans; Hydrocortisone; Imidazoles; Ketoconazole; Male; Piperazines; Rats | 1982 |
Ketoconazole therapy in advanced prostatic cancer.
Topics: Acid Phosphatase; Aged; Androstenedione; Dehydroepiandrosterone; Follow-Up Studies; Humans; Ketoconazole; Male; Prostatic Neoplasms; Testosterone; Time Factors | 1984 |
Steroid metabolism by rabbit olfactory-specific P450 2G1.
Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Dihydrotestosterone; Estradiol; Female; Ketoconazole; Kinetics; Male; NADP; Olfactory Mucosa; Progesterone; Rabbits; Steroids; Substrate Specificity; Testosterone | 1994 |
Effect of aromatase inhibitors on estrogen 2-hydroxylase in rat liver.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Fadrozole; Female; Ketoconazole; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases; Substrate Specificity | 1994 |
Inhibition and inactivation of equine aromatase by steroidal and non-steroidal compounds. A comparison with human aromatase inhibition.
Topics: Androstenedione; Animals; Aromatase Inhibitors; Enzyme Activation; Fadrozole; Horses; Humans; Imidazoles; Ketoconazole; Male; Miconazole; Substrate Specificity | 1997 |
YM116, 2-(1H-imidazol-4-ylmethyl)-9H-carbazole, decreases adrenal androgen synthesis by inhibiting C17-20 lyase activity in NCI-H295 human adrenocortical carcinoma cells.
Topics: Adrenal Cortex Hormones; Adrenocortical Carcinoma; Androgens; Androstenedione; Carbazoles; Dehydroepiandrosterone; Enzyme Inhibitors; Humans; Imidazoles; Ketoconazole; Male; Microsomes; Steroid 17-alpha-Hydroxylase; Testis; Tumor Cells, Cultured | 1999 |
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men.
Topics: Adolescent; Adult; Aged; Aging; Androgens; Androstenedione; Dehydroepiandrosterone; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Ketoconazole; Luteinizing Hormone; Male; Middle Aged; Prolactin; Radioimmunoassay; Reference Values; Sensitivity and Specificity; Testosterone; Thyrotropin; Time Factors | 2001 |
Metabolism of the polycyclic musk galaxolide and its interference with endogenous and xenobiotic metabolizing enzymes in the European sea bass (Dicentrarchus labrax).
Topics: 17-alpha-Hydroxyprogesterone; Androstenedione; Animals; Bass; Benzopyrans; Bile; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP3A; Endocrine Disruptors; Fatty Acids, Monounsaturated; Female; Glucuronosyltransferase; Gonads; Inactivation, Metabolic; Ketoconazole; Liver; Male; Water Pollutants, Chemical | 2013 |
Steroid synthesis by Taenia crassiceps WFU cysticerci is regulated by enzyme inhibitors.
Topics: Androstenedione; Animals; Chromatography, Thin Layer; Danazol; Desoxycorticosterone; Enzyme Inhibitors; Estradiol; Ketoconazole; Steroids; Taenia | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |