Page last updated: 2024-08-17

androstenedione and atamestane

androstenedione has been researched along with atamestane in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199012 (32.43)18.7374
1990's19 (51.35)18.2507
2000's6 (16.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henderson, D1
di Salle, E; Giudici, D; Ornati, G; Panzeri, A; Zaccheo, T1
Khan, SA; Nieschlag, E; Simoni, M1
Briatico, G; di Salle, E; Giudici, D; Ornati, G1
el Etreby, MF; Habenicht, UF; Henderson, D; Kerb, U; Nishino, Y1
el Etreby, MF; Habenicht, UF4
Aumüller, G; el Etreby, MF; Habenicht, UF1
el Etreby, MF; Habenicht, UF; Neumann, F; Schwarz, K1
el Etreby, MF; Ghoniem, G; Habenicht, UF; Lewis, R; Roberts, J1
Briatico, G; di Salle, E; Giudici, D; Ornati, G; Zaccheo, T1
el Etreby, MF; Michna, H; Nishino, Y; Schneider, MR1
Habenicht, UF; Hochstrate, H; Krieg, M; Tunn, S1
el Etreby, MF; Schröder, H; Ziegler, M1
Henderson, D; Kerb, U; Norbisrath, G1
Goldschmidt, AJ; Tunn, UW1
Andriole, GL; Keetch, DW1
el Etreby, MF; Gormley, GJ; Imperato-McGinley, JL; Oesterling, JE; Roehrborn, CG; Schröder, FH; Tunn, UW1
Gingell, JC; Knönagel, H; Kurth, KH; Tunn, UW1
Ekman, P1
Bartsch, G; el Etreby, MF; Habenicht, UF; Schröder, FH; Schweikert, HU; Senge, T; Tunn, UW1
el Etreby, MF1
Arnold, J; Blom, JH; Ennemoser, O; Habenicht, UF; Horniger, W; Schröder, FH; Schulze, H; Schweikert, HU; Senge, T; Tunn, UW1
Hakky, SI; Hudson, PB; Lombardo, ME1
Höffken, K1
Bono, AV; Eickenberg, HU; Fletcher, MS; Fourcade, RO; Radlmaier, A; Reis Santos, JM; van Aubel, OG1
Andreani, CL; Caruso, A; Cento, R; Lanzone, A; Lazzarin, N; Mancuso, S; Pierro, E1
Harada, N; Hatano, O1
Bidlingmaier, F; Hans, VH; Heidrich, DD; Klingmüller, D; Schramm, J; Steckelbroeck, S; Stoffel-Wagner, B1
Grobbee, DE; Lamberts, SW; Muller, M; van den Beld, AW; van der Schouw, YT1
Cheung, AM; Goss, PE; Hu, H; Qi, S1
Blanchett, D; Demers, L; Goss, PE; Langecker, P; Ohorodnik, S; Santen, RJ; Settlage, J; Wang, S1
Brodie, A; Goloubeva, O; Macedo, L; Sabnis, GJ; Schayowitz, A; Zhu, Y1
Blanchett, D; Bondarenko, IN; Goss, P; Langecker, P; Manikhas, GN; Miller, WH; Pendergrass, KB1
Goss, PE; Hu, H; Qi, S1

Reviews

5 review(s) available for androstenedione and atamestane

ArticleYear
The function and the role of aromatase inhibitors in the treatment of BPH.
    Progress in clinical and biological research, 1994, Volume: 386

    Topics: Androgens; Androstenedione; Animals; Aromatase Inhibitors; Clinical Trials as Topic; Disease Models, Animal; Estrogens; Flutamide; Humans; Macaca fascicularis; Male; Prostate; Prostatic Hyperplasia

1994
Endocrine therapies for BPH: scientific rationale, clinical results, and patient selection.
    Progress in clinical and biological research, 1994, Volume: 386

    Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Androgens; Androstenedione; Animals; Aromatase Inhibitors; Clinical Trials as Topic; Gonadotropin-Releasing Hormone; Hormones; Humans; Male; Models, Biological; Patient Selection; Prostate; Prostatic Hyperplasia

1994
Management of benign prostatic hyperplasia with particular emphasis on aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Estradiol; Humans; Male; Prostatic Hyperplasia; Tamoxifen

1993
Atamestane: an aromatase inhibitor for the treatment of benign prostatic hyperplasia. A short review.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Androgens; Androstenedione; Animals; Aromatase Inhibitors; Dogs; Estrogens; Female; Humans; Male; Ovary; Prostatic Hyperplasia; Receptors, Androgen; Receptors, Estrogen

1993
Experience with aromatase inhibitors in the treatment of advanced breast cancer.
    Cancer treatment reviews, 1993, Volume: 19 Suppl B

    Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Forecasting; Humans

1993

Trials

6 trial(s) available for androstenedione and atamestane

ArticleYear
Placebo controlled double-blind study to test the efficacy of the aromatase inhibitor atamestane in patients with benign prostatic hyperplasia not requiring operation. The Schering 90.062 Study Group.
    The Journal of urology, 1995, Volume: 154, Issue:2 Pt 1

    Topics: Aged; Androstenedione; Aromatase Inhibitors; Double-Blind Method; Humans; Male; Prospective Studies; Prostatic Hyperplasia

1995
Endocrine therapy for benign prostatic hyperplasia in the 90's.
    Journal d'urologie, 1995, Volume: 101, Issue:1

    Topics: Androstenedione; Aromatase Inhibitors; Controlled Clinical Trials as Topic; Double-Blind Method; Enzyme Inhibitors; Finasteride; Humans; Male; Placebos; Prostatic Hyperplasia; Testolactone

1995
Estrogen reduction by aromatase inhibition for benign prostatic hyperplasia: results of a double-blind, placebo-controlled, randomized clinical trial using two doses of the aromatase-inhibitor atamestane. Atamestane Study Group.
    The Prostate, 1996, Volume: 29, Issue:4

    Topics: Aged; Androgens; Androstenedione; Aromatase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrone; Humans; Male; Middle Aged; Placebos; Prostatic Hyperplasia

1996
Effects of dehydroepiandrosterone and atamestane supplementation on frailty in elderly men.
    The Journal of clinical endocrinology and metabolism, 2006, Volume: 91, Issue:10

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Androstenedione; Bone Density; Dehydroepiandrosterone; Double-Blind Method; Frail Elderly; Hormone Replacement Therapy; Humans; Male; Testosterone

2006
Superiority of gas chromatography/tandem mass spectrometry assay (GC/MS/MS) for estradiol for monitoring of aromatase inhibitor therapy.
    Steroids, 2007, Volume: 72, Issue:8

    Topics: Androstenedione; Aromatase Inhibitors; Biological Assay; Breast Neoplasms; Estradiol; Female; Gas Chromatography-Mass Spectrometry; Humans; Letrozole; Nitriles; Placebos; Postmenopause; Radioimmunoassay; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazoles

2007
Phase III, double-blind, controlled trial of atamestane plus toremifene compared with letrozole in postmenopausal women with advanced receptor-positive breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Nov-01, Volume: 25, Issue:31

    Topics: Aged; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Disease Progression; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Steroid; Toremifene; Triazoles

2007

Other Studies

26 other study(ies) available for androstenedione and atamestane

ArticleYear
Estrogens and benign prostatic hyperplasia: rationale for therapy with aromatase inhibitors.
    Annals of medicine, 1991, Volume: 23, Issue:3

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Estrogens; Humans; Male; Prostatic Hyperplasia

1991
Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Cell Division; Dose-Response Relationship, Drug; Endocrine Glands; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Organ Size; Ovariectomy; Pargyline; Prolactin; Rats

1991
Serum bioactive follicle-stimulating hormone-like activity in human pregnancy is a methodological artifact.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 73, Issue:5

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Artifacts; Biological Assay; Cells, Cultured; Estradiol; Female; Follicle Stimulating Hormone; Humans; Kinetics; Male; Pregnancy; Rats; Rats, Inbred Strains; Sertoli Cells

1991
Novel irreversible aromatase inhibitors.
    Annals of the New York Academy of Sciences, 1990, Volume: 595

    Topics: Aminoglutethimide; Androstadienes; Androstenedione; Animals; Aromatase Inhibitors; Female; Gonadotropins, Equine; Humans; In Vitro Techniques; Kinetics; Microsomes; Ovary; Pargyline; Placenta; Rats; Rats, Inbred Strains

1990
Aromatase inhibitors and benign prostatic hyperplasia.
    Journal of steroid biochemistry, 1986, Volume: 25, Issue:5B

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Gonadotropins, Equine; Humans; Kinetics; Male; Prostatic Hyperplasia; Species Specificity

1986
Synergic inhibitory effects of the aromatase inhibitor 1-methyl-androsta-1, 4-diene-3, 17-dione and the antiandrogen cyproterone acetate on androstenedione-induced hyperplastic effects in the prostates of castrated dogs.
    The Prostate, 1987, Volume: 11, Issue:2

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Castration; Cyproterone; Cyproterone Acetate; Dogs; Drug Synergism; Drug Therapy, Combination; Male; Prostate; Prostatic Hyperplasia; Time Factors

1987
Pharmacologically induced ultrastructural and immunohistochemical changes in the prostate of the castrated dog.
    The Prostate, 1987, Volume: 11, Issue:3

    Topics: Acid Phosphatase; Androstenedione; Animals; Aromatase Inhibitors; Castration; Cyproterone; Dogs; Immunohistochemistry; Keratins; Male; Prostate; Vimentin

1987
Induction of estrogen-related hyperplastic changes in the prostate of the cynomolgus monkey (Macaca fascicularis) by androstenedione and its antagonization by the aromatase inhibitor 1-methyl-androsta-1,4-diene-3,17-dione.
    The Prostate, 1987, Volume: 11, Issue:4

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Disease Models, Animal; Estradiol; Macaca fascicularis; Male; Organ Size; Prostate; Prostatic Hyperplasia

1987
Selective inhibition of androstenedione-induced prostate growth in intact beagle dogs by a combined treatment with the antiandrogen cyproterone acetate and the aromatase inhibitor 1-methyl-androsta-1,4-diene-3,17-dione (1-methyl-ADD).
    The Prostate, 1989, Volume: 14, Issue:4

    Topics: Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Cyproterone; Cyproterone Acetate; Dogs; Epididymis; Luteinizing Hormone; Male; Organ Size; Prostate; Prostatic Hyperplasia; Radioimmunoassay; Testis

1989
Induction of metachromasia in experimentally induced hyperplastic/hypertrophic changes in the prostate of the cynomolgus monkey (Macaca fascicularis).
    The Journal of urology, 1989, Volume: 142, Issue:6

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Macaca fascicularis; Male; Prostate; Prostatic Hyperplasia; Staining and Labeling

1989
Aromatase inhibition and experimental antitumor activity of FCE 24304, MDL 18962 and SH 489.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstadienes; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Female; Humans; Luteinizing Hormone; Male; Mammary Neoplasms, Experimental; Microsomes; Orchiectomy; Ovary; Pargyline; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Reference Values

1989
Antitumor effect of a specific aromatase inhibitor, 1-methyl-androsta-1,4-diene-3,17-dione (atamestane), in female rats bearing DMBA-induced mammary tumors.
    Journal of steroid biochemistry, 1989, Volume: 34, Issue:1-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenedione; Animals; Antineoplastic Agents; Aromatase Inhibitors; Fadrozole; Female; Imidazoles; Mammary Neoplasms, Experimental; Nitriles; Rats; Rats, Inbred Strains

1989
5 alpha-reductase activity in epithelium and stroma of prostates from intact and castrated dogs treated with androstenedione, the aromatase inhibitor 1-methyl-1,4-androstadiene-3,17-dione, and cyproterone acetate.
    The Prostate, 1988, Volume: 12, Issue:3

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Aromatase Inhibitors; Cyproterone; Cyproterone Acetate; Drug Interactions; Epithelium; Kinetics; Male; Orchiectomy; Prostate

1988
Aromatase-inhibitors of the androstenedione-type activate the 17 beta-hydroxysteroid-dehydrogenase in the rat testis tissue suspension model.
    Journal of steroid biochemistry, 1988, Volume: 31, Issue:4B

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstenedione; Animals; Aromatase Inhibitors; Culture Techniques; Dihydrotestosterone; Enzyme Activation; Male; Rats; Structure-Activity Relationship; Testis; Testosterone

1988
Effect of aromatase inhibitors on the functional morphology of the pituitary gland of dogs and monkeys.
    Pathology, research and practice, 1988, Volume: 183, Issue:5

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Cyproterone; Dogs; Macaca fascicularis; Male; Organ Size; Pituitary Gland; Pituitary Hormones; Rats; Reference Values; Species Specificity; Testis

1988
1-Methyl-1,4-androstadiene-3,17-dione (SH 489): characterization of an irreversible inhibitor of estrogen biosynthesis.
    Journal of steroid biochemistry, 1986, Volume: 24, Issue:1

    Topics: Androstenedione; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; Oxidation-Reduction; Placenta; Pregnancy; Structure-Activity Relationship

1986
[Aromatase inhibitors in the medical treatment of benign prostatic hypertrophy].
    Journal d'urologie, 1993, Volume: 99, Issue:6

    Topics: Androstenedione; Aromatase Inhibitors; Humans; Male; Prostatic Hyperplasia

1993
Medical therapy for benign prostatic hyperplasia.
    AJR. American journal of roentgenology, 1995, Volume: 164, Issue:1

    Topics: Adrenergic alpha-Antagonists; Androstenedione; Aromatase Inhibitors; Finasteride; Gonadotropin-Releasing Hormone; Humans; Male; Prostatic Hyperplasia

1995
Effects of estrogen deprivation on human benign prostatic hyperplasia.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Aged; Aged, 80 and over; Androstenedione; Aromatase Inhibitors; Estradiol; Estrone; Humans; Male; Middle Aged; Prostate; Prostatic Hyperplasia

1993
In vitro studies on the inhibition of testosterone synthesis in the human testis by atamestane.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Aged; Androstenedione; Binding, Competitive; Humans; In Vitro Techniques; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testis; Testosterone

1993
Further evidence of increased aromatase activity in granulosa luteal cells from polycystic ovary.
    Human reproduction (Oxford, England), 1997, Volume: 12, Issue:9

    Topics: Adult; Androstenedione; Aromatase; Aromatase Inhibitors; Cell Count; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Granulosa Cells; Humans; Insulin; Kinetics; Luteal Cells; Polycystic Ovary Syndrome; Progesterone

1997
Inhibitors of aromatase prevent degradation of the enzyme in cultured human tumour cells.
    British journal of cancer, 1998, Volume: 77, Issue:4

    Topics: Androstenedione; Aromatase; Aromatase Inhibitors; Carcinoma, Hepatocellular; Choriocarcinoma; Colforsin; Cycloheximide; Enzyme-Linked Immunosorbent Assay; Fadrozole; Humans; Liver Neoplasms; Neoplasm Proteins; Protein Synthesis Inhibitors; RNA, Messenger; Triazoles; Tumor Cells, Cultured

1998
Characterization of aromatase cytochrome P450 activity in the human temporal lobe.
    The Journal of clinical endocrinology and metabolism, 1999, Volume: 84, Issue:8

    Topics: Adolescent; Adult; Age Factors; Androstenedione; Aromatase; Azasteroids; Child; Dose-Response Relationship, Drug; Female; Finasteride; Humans; Kinetics; Male; Middle Aged; Organ Specificity; Placenta; Sex Factors; Temporal Lobe

1999
The effects of atamestane and toremifene alone and in combination compared with letrozole on bone, serum lipids and the uterus in an ovariectomized rat model.
    Breast cancer research and treatment, 2007, Volume: 103, Issue:3

    Topics: Androstenedione; Animals; Antineoplastic Combined Chemotherapy Protocols; Disease Models, Animal; Female; Humans; Letrozole; Lipids; Models, Chemical; Nitriles; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Toremifene; Triazoles; Uterus

2007
Toremifene-atamestane; alone or in combination: predictions from the preclinical intratumoral aromatase model.
    The Journal of steroid biochemistry and molecular biology, 2008, Volume: 108, Issue:1-2

    Topics: Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Breast Neoplasms; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, SCID; Prognosis; Toremifene; Transfection; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2008
Comparing the effects of atamestane, toremifene and tamoxifen alone and in combination, on bone, serum lipids and uterus in ovariectomized rats.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 113, Issue:3-5

    Topics: Androstenedione; Animals; Aromatase Inhibitors; Body Weight; Bone Density; Bone Density Conservation Agents; Clinical Trials as Topic; Compressive Strength; Epithelial Cells; Estrogen Antagonists; Female; Femur; Humans; Lipids; Lumbar Vertebrae; Ovariectomy; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Tamoxifen; Toremifene; Uterus

2009