Page last updated: 2024-08-21

androstenediol and androsterone

androstenediol has been researched along with androsterone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19909 (32.14)18.7374
1990's8 (28.57)18.2507
2000's9 (32.14)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chapman, D; Jain, AN; Koile, K1
Good, AC; Richards, WG; So, SS1
Platt, DE; Silverman, BD1
Crippen, GM1
Karplus, M; So, SS1
Hamprecht, FA; Kubinyi, H; Mietzner, T1
Strassburg, CP; Tukey, RH1
Clementi, S; Cruciani, G; McLay, I; Pastor, M; Pickett, S1
Baumann, K; Stiefl, N1
Higashiura, K; Kotani, T1
Ernst, B; Lill, MA; Vedani, A; Winiger, F1
Ban, F; Cherkasov, A; Fallahi, M; Hammond, GL; Santos-Filho, O; Thorsteinson, N1
Bellavance, E; Luu-The, V; Poirier, D1
Hay, JB; Hodgins, MB; Sharp, F1
MacDonald, PC; Milewich, L; Stephens, P; Winters, AJ1
Bird, CE; Boroomand, K; Clark, AF; Dressel, D; Finnis, W; Murphy, J1
Djøseland, O; Hastings, CD1
Bélanger, A; Brochu, M; Cliche, J1
Bélanger, A; Brochu, M; Cusan, L; Dupont, A; Labrie, F1
Faredin, I; Tóth, I1
Hendricks, TS; Johnson, AR; Milewich, L1
Bird, CE; Clark, AF; Masters, V; Tremblay, J1
Falany, CN; Falany, JL; Oh, TS; Wheeler, J1
Baulieu, EE; Brailly, S; Chanson, P; Couzinet, B; Nahoul, K; Schaison, G; Young, J1
Bélanger, A; Deshaies, Y; Després, JP; Labrie, F; Lacaille, M; Langin, D; Martel, C; Mauriège, P1
Jasso-Kamel, J; Montaño, LM; Navarrete, E; Perusquía, M1
Balser, J; Labrie, F; Martel, C1
Białońska, A; Kołek, T; Milecka, N; Panek, A; Świzdor, A1

Reviews

1 review(s) available for androstenediol and androsterone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Trials

1 trial(s) available for androstenediol and androsterone

ArticleYear
Panhypopituitarism as a model to study the metabolism of dehydroepiandrosterone (DHEA) in humans.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:8

    Topics: Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Female; Humans; Hypopituitarism; Male; Middle Aged; Models, Biological; Placebos; Testosterone

1997

Other Studies

26 other study(ies) available for androstenediol and androsterone

ArticleYear
Compass: predicting biological activities from molecular surface properties. Performance comparisons on a steroid benchmark.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Algorithms; Models, Molecular; Models, Statistical; Molecular Conformation; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Surface Properties; Transcortin

1994
Structure-activity relationships from molecular similarity matrices.
    Journal of medicinal chemistry, 1993, Feb-19, Volume: 36, Issue:4

    Topics: Computer Simulation; Electrochemistry; Models, Molecular; Molecular Structure; Neural Networks, Computer; Sex Hormone-Binding Globulin; Steroids; Structure-Activity Relationship; Transcortin

1993
Comparative molecular moment analysis (CoMMA): 3D-QSAR without molecular superposition.
    Journal of medicinal chemistry, 1996, May-24, Volume: 39, Issue:11

    Topics: Adrenal Cortex Hormones; Binding Sites; Mathematics; Models, Molecular; Molecular Conformation; Molecular Structure; Molecular Weight; Predictive Value of Tests; Steroids; Structure-Activity Relationship; Testosterone

1996
Validation of EGSITE2, a mixed integer program for deducing objective site models for experimental binding data.
    Journal of medicinal chemistry, 1997, Sep-26, Volume: 40, Issue:20

    Topics: Algorithms; Animals; Binding Sites; Computer Simulation; Folic Acid Antagonists; Models, Molecular; Peptidyl-Dipeptidase A; Protein Binding; Receptors, Cell Surface; Sex Hormone-Binding Globulin; Steroids; Testosterone; Tetrahydrofolate Dehydrogenase; Transcortin

1997
Three-dimensional quantitative structure-activity relationships from molecular similarity matrices and genetic neural networks. 1. Method and validations.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Algorithms; Models, Chemical; Molecular Structure; Neural Networks, Computer; Protein Binding; Static Electricity; Steroids; Structure-Activity Relationship; Transcortin

1997
Three-dimensional quantitative similarity-activity relationships (3D QSiAR) from SEAL similarity matrices.
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: Drug Design; Least-Squares Analysis; Molecular Conformation; Steroids; Structure-Activity Relationship; Transcortin

1998
GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors.
    Journal of medicinal chemistry, 2000, Aug-24, Volume: 43, Issue:17

    Topics: Butyrophenones; Enzyme Inhibitors; Glucose; Models, Molecular; Phosphorylases; Protein Binding; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Software; Steroids; Transcortin

2000
Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique.
    Journal of medicinal chemistry, 2003, Apr-10, Volume: 46, Issue:8

    Topics: Acetates; Alcohols; Algorithms; Cholinergic Agents; Hydrocarbons, Acyclic; Hydrocarbons, Aromatic; Ketones; Models, Molecular; Protein Binding; Quantitative Structure-Activity Relationship; Receptor, Muscarinic M2; Receptors, Muscarinic; Steroids; Transcortin

2003
Comparative molecular active site analysis (CoMASA). 1. An approach to rapid evaluation of 3D QSAR.
    Journal of medicinal chemistry, 2004, May-20, Volume: 47, Issue:11

    Topics: Binding Sites; Cluster Analysis; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Quantitative Structure-Activity Relationship; Steroids

2004
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
    Journal of medicinal chemistry, 2005, Sep-08, Volume: 48, Issue:18

    Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics

2005
An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Binding Sites; Binding, Competitive; Computer Simulation; Databases as Topic; Humans; Ligands; Linear Models; Models, Molecular; Predictive Value of Tests; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Sex Hormone-Binding Globulin; Steroids

2008
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone.
    Journal of medicinal chemistry, 2009, Dec-10, Volume: 52, Issue:23

    Topics: 17-Hydroxysteroid Dehydrogenases; Androstane-3,17-diol; Androstanes; Biocatalysis; Cell Line; Dihydrotestosterone; Enzyme Inhibitors; Estradiol; Estrone; Humans; Inhibitory Concentration 50; Oxidation-Reduction; Substrate Specificity

2009
Metabolism of androgens in vitro by human foetal skin.
    The Journal of endocrinology, 1976, Volume: 70, Issue:3

    Topics: 17-Ketosteroids; Androgens; Androstenediol; Androstenedione; Androsterone; Culture Techniques; Dehydroepiandrosterone; Dihydrotestosterone; Fetus; Gestational Age; Humans; Hydroxysteroid Dehydrogenases; Male; Sebaceous Glands; Skin; Testosterone

1976
Metabolism of dehydroisoandrosterone and androstenedione by the human lung in vitro.
    Journal of steroid biochemistry, 1977, Volume: 8, Issue:4

    Topics: Androstenediol; Androstenedione; Androsterone; Dehydroepiandrosterone; Female; Humans; In Vitro Techniques; Lung; Middle Aged; Testosterone

1977
Dehydroepiandrosterone: kinetics of metabolism in normal men and women.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: Adolescent; Adult; Androstenediol; Androstenedione; Androsterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Sex Factors

1978
Androgen metabolism by rat epididymis: metabolic conversion of 3H-dihydrotestosterone in vivo and in vitro.
    Archives of andrology, 1979, Volume: 2, Issue:3

    Topics: Androstanes; Androstenediol; Androsterone; Animals; Dihydrotestosterone; Epididymis; Ketosteroids; Male; Rats

1979
Levels of plasma steroid glucuronides in intact and castrated men with prostatic cancer.
    The Journal of clinical endocrinology and metabolism, 1986, Volume: 62, Issue:5

    Topics: Aged; Androgens; Androstane-3,17-diol; Androstenediol; Androsterone; Dehydroepiandrosterone; Dihydrotestosterone; Glucuronates; Humans; Male; Middle Aged; Orchiectomy; Prostatic Neoplasms; Testosterone

1986
Endocrine effects of combined treatment with an LHRH agonist in association with flutamide in metastatic prostatic carcinoma.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1988, Volume: 11, Issue:5

    Topics: Adenocarcinoma; Adrenal Cortex Hormones; Androgens; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Anilides; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Dehydroepiandrosterone; Flutamide; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Kinetics; Luteinizing Hormone; Male; Pregnenolone; Progesterone; Prolactin; Prostatic Neoplasms; Testosterone; Triptorelin Pamoate

1988
Steroids excreted by human skin. II. C19-steroid sulphates in human axillary sweat.
    Acta medica Hungarica, 1985, Volume: 42, Issue:1-2

    Topics: Adolescent; Adult; Androstenediol; Androstenediols; Androsterone; Axilla; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Humans; Male; Sex Factors; Sweat; Testosterone

1985
Metabolism of dehydroisoandrosterone and androstenedione in human pulmonary endothelial cells in culture.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 56, Issue:5

    Topics: Androstenediol; Androstenedione; Androsterone; Cells, Cultured; Dehydroepiandrosterone; Dihydrotestosterone; Endothelium; Etiocholanolone; Humans; Male; Pulmonary Artery; Pulmonary Veins; Testosterone

1983
Delta 5-androstenediol: kinetics of metabolism and binding to plasma proteins in normal post-menopausal women.
    Acta endocrinologica, 1982, Volume: 99, Issue:2

    Topics: Aged; Androstenediol; Androstenediols; Androstenedione; Androsterone; Blood Proteins; Dehydroepiandrosterone; Female; Humans; Kinetics; Menopause; Metabolic Clearance Rate; Middle Aged; Protein Binding; Testosterone

1982
Steroid sulfation by expressed human cytosolic sulfotransferases.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 48, Issue:4

    Topics: Amino Acid Sequence; Androstenediol; Androsterone; Arylsulfotransferase; Base Sequence; Cytosol; Escherichia coli; Estrogens; Gene Expression; Humans; Molecular Sequence Data; Recombinant Proteins; Steroids; Substrate Specificity; Sulfates; Sulfotransferases; Testosterone

1994
Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism.
    Metabolism: clinical and experimental, 2003, Volume: 52, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Androstenediol; Androstenedione; Androsterone; Animals; Dehydroepiandrosterone; Fasting; Female; Insulin; Lipoprotein Lipase; Organ Size; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Sterol Esterase; Testosterone; Triglycerides

2003
Androgens induce relaxation of contractile activity in pregnant human myometrium at term: a nongenomic action on L-type calcium channels.
    Biology of reproduction, 2005, Volume: 73, Issue:2

    Topics: Androgen Antagonists; Androgens; Androstenediol; Androsterone; Calcium Channels, L-Type; Dehydroepiandrosterone; Dihydrotestosterone; Dose-Response Relationship, Drug; Female; Flutamide; Humans; In Vitro Techniques; Isometric Contraction; Muscle Relaxation; Muscle, Smooth; Myometrium; Pregnancy; Protein Synthesis Inhibitors; Statistics, Nonparametric; Testosterone; Uterine Contraction

2005
Wide distribution of the serum dehydroepiandrosterone and sex steroid levels in postmenopausal women: role of the ovary?
    Menopause (New York, N.Y.), 2011, Volume: 18, Issue:1

    Topics: Adult; Aged; Androstane-3,17-diol; Androstenediol; Androstenedione; Androsterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Middle Aged; Ovariectomy; Ovary; Postmenopause; Statistics, Nonparametric; Testosterone

2011
Hydroxylation of DHEA, androstenediol and epiandrosterone by Mortierella isabellina AM212. Evidence indicating that both constitutive and inducible hydroxylases catalyze 7α- as well as 7β-hydroxylations of 5-ene substrates.
    Organic & biomolecular chemistry, 2011, Aug-07, Volume: 9, Issue:15

    Topics: Androstenediol; Androsterone; Binding Sites; Catalysis; Crystallography, X-Ray; Cycloheximide; Dehydroepiandrosterone; Hydroxylation; Ketoconazole; Mixed Function Oxygenases; Molecular Structure; Mortierella

2011