androstane-3-17-diol-glucuronide has been researched along with 11-hydroxytestosterone* in 1 studies
1 other study(ies) available for androstane-3-17-diol-glucuronide and 11-hydroxytestosterone
| Article | Year |
|---|---|
Synthesis of a precursor for the preparation of 9 alpha,11 alpha-tritiated 5 alpha-androstane-3 alpha,17 beta-diol 17-glucuronide.
Starting from 11 beta-hydroxytestosterone, we achieved the synthesis of a strategic precursor, C-9 (11) unsaturated 5 alpha-androstane-3 alpha, 17 beta-diol 17-glucuronide (9a), for the preparation of 9 alpha,11 alpha-tritiated 5 alpha-androstane-3 alpha, 17 beta-diol 17-glucuronide. We optimized the reaction conditions for catalytic reduction employing hydrogen and subsequent base hydrolysis followed by purification on Amberlite XAD-2 resin to obtain the saturated 5 alpha-androstane-3 alpha, 17 beta-diol 17-glucuronide. Topics: Androstane-3,17-diol; Androstanols; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Hydroxytestosterones; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mass Spectrometry; Testosterone; Tritium | 1984 |