Page last updated: 2024-09-04

androst-4-ene-3,6,17-trione and androstenedione

androst-4-ene-3,6,17-trione has been researched along with androstenedione in 5 studies

Compound Research Comparison

Studies
(androst-4-ene-3,6,17-trione)
Trials
(androst-4-ene-3,6,17-trione)
Recent Studies (post-2010)
(androst-4-ene-3,6,17-trione)
Studies
(androstenedione)
Trials
(androstenedione)
Recent Studies (post-2010) (androstenedione)
17027,175377960

Protein Interaction Comparison

ProteinTaxonomyandrost-4-ene-3,6,17-trione (IC50)androstenedione (IC50)
CholinesteraseHomo sapiens (human)1.55
AromataseHomo sapiens (human)0.3
Androgen receptorRattus norvegicus (Norway rat)0.6761
Testosterone 17-beta-dehydrogenase 3Homo sapiens (human)0.6826

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Booth, JE1
Covey, DF; Hood, WF1
Mutsumi, A; Numazawa, M; Tachibana, M1
Numazawa, M1
Cheng, KD; Feng, WH; He, HX; Liu, Y; Ma, XJ; Meng, C; Zhu, HX; Zhu, P1

Reviews

1 review(s) available for androst-4-ene-3,6,17-trione and androstenedione

ArticleYear
[Development of aromatase inhibitors and analysis of their inhibitory activities].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1998, Volume: 118, Issue:12

    Topics: Androstenedione; Androstenes; Aromatase; Aromatase Inhibitors; Binding Sites; Binding, Competitive; Catalysis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Isomerism; Structure-Activity Relationship; Time Factors

1998

Other Studies

4 other study(ies) available for androst-4-ene-3,6,17-trione and androstenedione

ArticleYear
Effects of the aromatization inhibitor androst-4-ene-3,6,17-trione on sexual differentiation induced by testosterone in the neonatally castrated rat.
    The Journal of endocrinology, 1978, Volume: 79, Issue:1

    Topics: Androstenedione; Androstenes; Animals; Castration; Female; Male; Organ Size; Ovary; Rats; Sex Differentiation; Sexual Behavior, Animal; Testosterone; Transplantation, Isogeneic

1978
A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Cancer research, 1982, Volume: 42, Issue:8 Suppl

    Topics: Androstadienes; Androstatrienes; Androstenedione; Androstenes; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Kinetics; Microsomes; Oxidoreductases; Placenta; Pregnancy; Structure-Activity Relationship; Testolactone

1982
Mechanism for aromatase inactivation by a suicide substrate, androst-4-ene-3,6,17-trione. The 4 beta, 5 beta-epoxy-19-oxo derivative as a reactive electrophile irreversibly binding to the active site.
    Biochemical pharmacology, 1996, Oct-25, Volume: 52, Issue:8

    Topics: Androstenedione; Androstenes; Aromatase; Aromatase Inhibitors; Binding Sites; Electrochemistry; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; Models, Chemical; Placenta; Pregnancy; Substrate Specificity

1996
[Biotransformation of dehydroepiandrosterone by hairy root cultures of Anisodus tanguticus].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:6

    Topics: Androstenedione; Androstenes; Biotransformation; Culture Media; Dehydroepiandrosterone; Molecular Structure; Plant Roots; Plants, Medicinal; Solanaceae; Tissue Culture Techniques

2004