anatoxin a has been researched along with mecamylamine in 6 studies
| Studies (anatoxin a) | Trials (anatoxin a) | Recent Studies (post-2010) (anatoxin a) | Studies (mecamylamine) | Trials (mecamylamine) | Recent Studies (post-2010) (mecamylamine) |
|---|---|---|---|---|---|
| 522 | 0 | 126 | 1,997 | 68 | 376 |
| Protein | Taxonomy | anatoxin a (IC50) | mecamylamine (IC50) |
|---|---|---|---|
| Neuronal acetylcholine receptor subunit beta-2 | Homo sapiens (human) | 0.44 | |
| Neuronal acetylcholine receptor subunit beta-4 | Homo sapiens (human) | 2.0833 | |
| Neuronal acetylcholine receptor subunit alpha-3 | Homo sapiens (human) | 1.6133 | |
| Neuronal acetylcholine receptor subunit alpha-7 | Homo sapiens (human) | 1.8 | |
| Neuronal acetylcholine receptor subunit alpha-4 | Homo sapiens (human) | 0.6 | |
| Neuronal acetylcholine receptor subunit alpha-2 | Homo sapiens (human) | 3.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dart, MJ; Holladay, MW; Lynch, JK | 1 |
| Albuquerque, EX; Garcha, HS; Stolerman, IP | 1 |
| Brough, PA; Gallagher, T; Livett, BG; Molloy, L; Wonnacott, S | 1 |
| Akaike, N; Katsurabayashi, S; Kiyosawa, A; Pang, ZP | 1 |
| Jones, IW; Pullar, IA; Rousseau, SJ; Wonnacott, S | 1 |
| Alfonso, M; Campos, F; Durán, R; Faro, LR; Vidal, L | 1 |
1 review(s) available for anatoxin a and mecamylamine
| Article | Year |
|---|---|
Neuronal nicotinic acetylcholine receptors as targets for drug discovery.
Topics: Acetylcholine; Animals; Binding Sites; Dopamine; Drug Design; Humans; Molecular Structure; Nervous System; Neurons; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Receptors, Nicotinic; Structure-Activity Relationship | 1997 |
5 other study(ies) available for anatoxin a and mecamylamine
| Article | Year |
|---|---|
Behavioural effects of anatoxin, a potent nicotinic agonist, in rats.
Topics: Animals; Bacterial Toxins; Behavior, Animal; Cyanobacteria Toxins; Discrimination, Psychological; Ganglionic Stimulants; Male; Marine Toxins; Mecamylamine; Microcystins; Motor Activity; Nicotine; Rats; Tropanes | 1992 |
Anatoxin-a is a potent agonist of the nicotinic acetylcholine receptor of bovine adrenal chromaffin cells.
Topics: Animals; Bacterial Toxins; Cattle; Cells, Cultured; Chromaffin System; Cyanobacteria Toxins; Epinephrine; Marine Toxins; Mecamylamine; Microcystins; Neurotoxins; Nicotine; Nicotinic Agonists; Norepinephrine; Potassium; Tropanes | 1995 |
Nicotine facilitates glycine release in the rat spinal dorsal horn.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha7 Nicotinic Acetylcholine Receptor; Anesthetics, Local; Animals; Bacterial Toxins; Bicuculline; Bungarotoxins; Calcium; Calcium Channels; Choline; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Marine Toxins; Mecamylamine; Microcystins; Nerve Endings; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nootropic Agents; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Nicotinic; Substantia Gelatinosa; Tetrodotoxin; Tropanes; Valine | 2001 |
Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Aspartic Acid; Azetidines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Calcium; Choline; Cyanobacteria Toxins; Dicarboxylic Acids; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Frontal Lobe; Immunohistochemistry; In Vitro Techniques; Male; Marine Toxins; Mecamylamine; Microcystins; Microscopy, Confocal; Neurotransmitter Uptake Inhibitors; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphopyruvate Hydratase; Potassium Chloride; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Presynaptic; Synaptosomes; Time Factors; Tritium; Tropanes | 2005 |
In vivo effects of the anatoxin-a on striatal dopamine release.
Topics: Aconitine; Animals; Bungarotoxins; Corpus Striatum; Cyanobacteria Toxins; Dopamine; Dose-Response Relationship, Drug; Female; Mecamylamine; Microdialysis; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tropanes | 2006 |