anastrozole has been researched along with triazoles in 1246 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (0.48) | 18.7374 |
| 1990's | 63 (5.06) | 18.2507 |
| 2000's | 644 (51.69) | 29.6817 |
| 2010's | 526 (42.22) | 24.3611 |
| 2020's | 7 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Demers, L; Dowsett, M; Dyroff, M; Plourde, PV; Webster, A; Yates, R | 1 |
| Dukes, M; Dyroff, M; Plourde, PV | 1 |
| Dowsett, M; Fisher, GV; Selen, A; Wyld, PJ; Yates, RA | 1 |
| Azab, M; Blomqvist, C; Buzdar, A; Eiermann, W; Howell, A; Jonat, W; Jones, SE; Plourde, PV; Vogel, CL; Webster, A; Wolter, JM | 1 |
| Castiglione-Gertsch, M | 1 |
| Azab, M; Blomqvist, C; Eiermann, W; Hellmund, R; Howell, A; Jonat, W; Lundgren, S; Mauriac, L; Roche, H; Tyrrell, C; Winblad, G | 1 |
| Buzdar, AU; Hortobagyi, GN; Plourde, PV | 1 |
| Dowsett, M; Geisler, J; King, N; Kormeset, PO; Lundgren, S; Lønning, PE; Ottestad, L; Walton, P | 1 |
| Boyle, T; Dukes, M; Edwards, PN; Large, M; Smith, IK | 1 |
| Buzdar, AU; Jones, SE; Plourde, P; Vogel, CL; Webster, A; Wolter, J | 1 |
| Hannaford, M | 1 |
| Dyroff, MC; Grimm, SW | 1 |
| Cala, KM; Landrum, DP; Mahendroo, MS; Russell, DW | 1 |
| Dowsett, M | 3 |
| Spencer, CM; Wiseman, LR | 1 |
| Durgam, VR; Tekmal, RR | 1 |
| Buzdar, AU; Howell, A; Jonat, W; Plourde, PV | 1 |
| Buzdar, AU; Roseman, BJ; Singletary, SE | 1 |
| Blamey, RW; Cheung, KL; Ellis, IO; Elston, CW; Nicholson, RI; Pinder, SE; Robertson, JF; Willsher, PC | 1 |
| Bara, I; Bock, MJ; Dyroff, M; LeDonne, N; Martz, A | 1 |
| Goss, PE; Tye, LM | 1 |
| Dukes, M | 1 |
| Dowsett, M; Lønning, PE | 1 |
| Jonat, W | 1 |
| Aparicio, LA; Carrion, RP; Dodwell, DJ; Dowsett, M; Kleeberg, UR; Robertson, JF; Vorobiof, DA | 1 |
| Ashby, J; Lefevre, PA | 1 |
| Flanagan, AM; Lea, CK | 1 |
| alKhouri, N; Higa, GM | 1 |
| Buzdar, AU | 15 |
| Bulun, SE; Carr, BR; Gunby, RT; Sasano, H; Takayama, K; Zeitoun, K | 1 |
| Harvey, HA | 1 |
| Brodie, A; Liu, Y; Long, B; Lu, Q; Wang, JP; Yue, W | 1 |
| Buzdar, AU; Hortobagyi, GN | 1 |
| Blomqvist, CP; Buzdar, AU; Eiermann, W; Howell, A; Jonat, W; Jones, SE; Lee, D; Steinberg, M; Vogel, CL; Webster, A; Wolter, JM | 1 |
| Lønning, PE | 3 |
| Kurokawa, K; Mamiya, Y; Okazaki, H; Ono, Y; Onuma, E; Suzuki, K; Suzuki, T; Takanashi, H; Yamanaka, H | 1 |
| Dowsett, M; Geisler, J; Lønning, PE | 1 |
| Brodie, A; Liu, Y; Long, B; Lu, Q; Wang, J; Yue, W | 1 |
| Adkins, JC; Wiseman, LR | 1 |
| Brodie, AM; Grigoryev, DN; Long, BJ; Thiantanawat, A; Tilghman, SL; Yue, W | 1 |
| Flanagan, AM; Lea, CK; Sarma, U | 1 |
| Baum, M; Blackman, GM; Dowsett, M; Howell, A; King, N; Ponzone, R; Tobias, JS; von Euler, M; Welch, H | 1 |
| Hamilton, A; Piccart, M | 1 |
| Lund, SA; Murdoch, J; Murdoch, WJ; Van Kirk, EA | 1 |
| Blijham, GH; de Jong, PC | 1 |
| Benson, S; Cella, D; Fallowfield, LJ; Howell, A; Leaity, SK | 1 |
| Coombes, RC; Harper-Wynne, C | 1 |
| Colciago, A; Motta, M; Negri-Cesi, P; Poletti, A | 1 |
| Bonneterre, J; Feutrie, ML | 1 |
| Calvo, L; Clack, G; Dodwell, DJ; Dowsett, M; Kleeberg, UR; Perez-Carrion, R; Robertson, JF; Vorobiof, DA | 1 |
| Brodie, A; Gimbel, M; Grigoryev, D; Liu, Y; Long, BJ; Lu, Q | 1 |
| Bland, KI; Buzdar, AU | 1 |
| Bland, KI | 1 |
| Atanassova, N; Morley, M; Sharpe, RM; Swanston, ID; Turner, KJ | 1 |
| Buzdar, A; Howell, A; Lee, D; Robertson, JF; von Euler, M | 1 |
| Bellamy, C; Cameron, DA; Dixon, JM; Leonard, RC; Love, CD; Miller, WR; Renshaw, L | 1 |
| Smith, IE | 2 |
| Harvey, HA; Santen, RJ | 1 |
| Bajetta, E; Bichisao, E; Pozzi, P; Toffolatti, L; Zilembo, N | 1 |
| Berntsen, H; Geisler, J; Lonning, PE | 1 |
| Bellamy, C; Dixon, JM; Hoctin-Boes, G; Miller, WR; Renshaw, L; Stuart, M | 1 |
| Hayes, V; Klein, KO; Mauras, N; O'Brien, KO | 1 |
| Donaldson, K; Dowsett, M; Tsuboi, M; Wong, J; Yates, R | 1 |
| Bulun, SE; Sasano, H; Takayama, K; Zeitoun, KM | 1 |
| Bell, J; Brunetto, VL; Lee, RB; Rose, PG; VanLe, L; Walker, JL | 1 |
| Fujiwara, K; Hohjoh, T; Ikeda, T; Kawaguchi, M; Kitajima, M; Masamura, S; Matsui, A; Mitsui, Y; Takayama, S; Tokura, H | 1 |
| Boepple, PA; Crowley, WF; Decruz, S; Hayes, FJ; Seminara, SB | 2 |
| Perey, L | 1 |
| Sonoo, H | 1 |
| Attolico, M; Crucitta, E; De Lena, M; Lorusso, V; Mazzei, A; Sambiasi, D | 1 |
| Dranitsaris, G; Leung, P; Mather, J; Oza, A | 1 |
| Buzdar, A | 2 |
| Bonneterre, J; Koralewski, L; Krzakowski, M; Mauriac, L; Robertson, J; Steinberg, M; Thürlimann, B; Vergote, I; von Euler, M; Webster, A | 1 |
| Bonneterre, J; Koralewski, P; Krzakowski, M; Mauriac, L; Robertson, JF; Steinberg, M; Thürlimann, B; Vergote, I; von Euler, M; Webster, A | 1 |
| Burton, G; Buzdar, A; Harwin, W; Mangalik, A; Nabholtz, JM; Pollak, M; Steinberg, M; von Euler, M; Webster, A | 1 |
| Fujita, T; Kaiho, S; Kuwabara, K; Ogata, E; Oizumi, I; Okazaki, T; Tanaka, Y | 1 |
| Sonoo, H; Watanabe, T | 1 |
| Howell, A | 4 |
| Cattel, F; Messori, A; Trippoli, S; Vaiani, M | 1 |
| Ashby, J; Joiner, R; Odum, J; Tinwell, H; Van Miller, J | 1 |
| Baum, M; Thornton, H; Tobias, JS | 1 |
| Cohen, MH; Flamm Honig, S; Hirschfeld, S; Ibrahim, A; Johnson, JR; O'Leary, JJ; Pazdur, R; White, RM; Williams, GA | 1 |
| Arosio, M; Faglia, G; Porretti, S | 1 |
| Bulun, SE; Takayama, K | 1 |
| Murdoch, WJ; Van Kirk, EA | 1 |
| Auvray, P; Bichat, F; Genne, P | 1 |
| de Crémoux, P | 1 |
| Kerbrat, P; Lefeuvre, C | 1 |
| Mokbel, K | 3 |
| Tsukagoshi, S | 1 |
| Panasci, LC | 1 |
| Bagley, CM; Rowbotham, RK | 1 |
| Bolton, M; Copur, MS; Ledakis, P; Muhvic, J; Norvell, M | 1 |
| Tonkin, K | 1 |
| Costa, SD; Kaufmann, M | 1 |
| Berntsen, H; Detre, S; Dowsett, M; Einstein Lønning, P; Geisler, J; Lindtjørn, B; Ottestad, L | 1 |
| Cameron, DA; Donnellan, PP; Douglas, SL; Leonard, RC | 1 |
| Bray, MJ; Schnorr, JA; Veldhuis, JD | 1 |
| Clive, JM; Fall, PM; Kennedy, DG; Raisz, LG; Taxel, P; Willard, AK | 1 |
| Bergmann, L | 1 |
| März, W; Merz, M; Nauck, M; Seiberling, M; Wong, J; Yates, RA | 1 |
| Tominaga, T | 1 |
| Cuzick, J; Dowsett, M; Howell, A; Jackson, I | 1 |
| Hamilton, A; Volm, M | 1 |
| Buzdar, A; Howell, A | 1 |
| Cohen, RB; Fisch, MJ; Myers, CE; Petroni, GR; Santen, RJ; Theodorescu, D | 1 |
| Burstein, HJ; Winer, EP | 1 |
| Murray, R | 1 |
| Boeddinghaus, I; Dixon, M; Dowsett, M; Ebbs, S; Gui, G; Harper-Wynne, C; Hills, M; Sacks, N; Salter, J; Smith, I | 1 |
| Bonneterre, J; Buzdar, A; Nabholtz, JM; Robertson, JF; Sahmoud, T; Steinberg, M; Thürlimann, B; von Euler, M; Webster, A | 1 |
| An, FR; Chen, J; Ge, SR; Liang, JY; Shi, AG; Wang, PQ; Yuan, J | 1 |
| Feng, F; Jiang, Z; Xu, B | 1 |
| Nabholtz, JM; Reese, DM | 1 |
| Bando, H; Saji, S; Toi, M | 1 |
| Raman, JD; Schlegel, PN | 1 |
| Anker, G; Dowsett, M; Geisler, J; Haynes, B; Lønning, PE | 1 |
| Carlini, P; Casali, A; Cognetti, F; De Marco, S; Fabi, A; Frassoldati, A; Nardi, M; Paoloni, F; Papaldo, P; Ruggeri, EM | 1 |
| Dixon, JM; Miller, WR | 1 |
| Anderson, TJ; Cameron, DA; Dixon, JM; Miller, WR | 1 |
| Junker, A; Possinger, K; Wiedemann, GJ | 1 |
| Cortvrindt, R; Hu, Y; Smitz, J | 1 |
| Sledge, GW | 1 |
| Baum, M | 4 |
| Chaudhuri, G; Dinh, H; Mukherjee, TK; Nathan, L | 1 |
| Cohen, Y; Geffen, DB; Lavrenkov, K; Man, S | 1 |
| Buzdar, A; Johnson, PE | 1 |
| Goss, PE | 1 |
| Nicholls, H | 1 |
| Soudon, J | 1 |
| Bajetta, E; Bombardieri, E; Buzzoni, R; Catena, L; Celio, L; Ferrari, L; Gattinoni, L; La Torre, I; Martinetti, A; Pozzi, P; Seregni, E; Vitali, M; Zilembo, N | 1 |
| Jones, SE | 1 |
| Casper, RF; Mitwally, MF | 1 |
| Benedetto, C; De Nicola, B; Ferraris, F; Genta, F; Piccinno, R; Porpiglia, M; Vicelli, R | 1 |
| Buzdar, AU; Giordano, SH; Hortobagyi, GN; Valero, V | 1 |
| Alba, E; Colla, F; Farina, C; Mazzoleni, A; Ragonesi, G | 1 |
| Lynn, J | 1 |
| Bajetta, E; Bichisao, E; Zilembo, N | 1 |
| Ravdin, P | 1 |
| Baum, M; Budzar, AU; Cuzick, J; Forbes, J; Houghton, JH; Klijn, JG; Sahmoud, T | 1 |
| Ingle, JN | 6 |
| Köberle, D; Thürlimann, B | 2 |
| Goss, PE; Smith, RE | 1 |
| Cummings, FJ | 1 |
| Assikis, VJ; Buzdar, A | 1 |
| Braun, S; Browman, GP; Burstein, HJ; Chlebowski, RT; Cobleigh, MA; Edge, SB; Goldstein, LJ; Gralow, J; Hudis, C; Ingle, JN; Langer, AS; Mamounas, EP; Perotti, J; Powles, TJ; Pritchard, KI; Whelan, TJ; Winer, EP | 1 |
| Bajetta, E; Bombardieri, E; Ferrari, L; La Torre, I; Longarini, R; Martinetti, A; Pozzi, P; Salvucci, G; Seregni, E; Zilembo, N | 1 |
| Burton, G; Buzdar, A; Come, S; Dimery, I; Elledge, R; Ellis, M; Gertler, SZ; Jones, SE; May, JT; Morris, C; Osborne, CK; Parker, LM; Pippen, J; Webster, A | 1 |
| Aschermannova, A; Erikstein, B; Howell, A; Kleeberg, UR; Mauriac, L; Morris, C; Quaresma Albano, J; Robertson, JF; Vergote, I; Webster, A | 1 |
| Anderson, TJ; Dixon, JM; Miller, WR; Sahmoud, T; Stuart, M | 1 |
| Nabholtz, JM; Reese, D | 1 |
| Albers, N; Freiberg, C; Roth, C; Zappel, H | 1 |
| Ashby, J; Deghenghi, R; Odum, J; Owens, W | 1 |
| Bramwell, V; Vandenberg, T; Winquist, E | 1 |
| Duan, G; Liang, J; Zuo, M | 1 |
| Enomoto, K; Kinoshita, T; Nishimura, M; Okamura, Y; Oura, S; Sakurai, T; Yokochi, H | 1 |
| Freed, DJ; Gillam, MP; Middler, S; Molitch, ME | 1 |
| Bruntsch, U | 1 |
| Buzdar, AU; Eiermann, W; Nabholtz, JM; Robertson, JF | 1 |
| Beat, T | 1 |
| Vergote, I | 1 |
| McClellan, MB | 1 |
| Faulds, DM; Wellington, K | 1 |
| Basu, S; Last, A; Shinkfield, M | 1 |
| Dixon, JM; Miller, WR; Sahmoud, T; Stuart, M | 1 |
| Gluck, S | 2 |
| Mokbel, K; Singh-Ranger, G | 2 |
| Hakamata, Y; Hozumi, Y; Nagai, H; Ogura, S; Sasanuma, H | 1 |
| Robertson, JF | 1 |
| Jordan, VC | 2 |
| Stasi, R; Terzoli, E | 1 |
| Thornton, H | 3 |
| Chiba, N; Mori, K; Yamamoto, Y; Yonekawa, H | 1 |
| Eastell, R; Finkelstein, JS; LeBlanc, KM; Leder, BZ; Schoenfeld, DA | 1 |
| Coleman, RE | 1 |
| Aumiller, J | 3 |
| Davidson, NE; Visvanathan, K | 1 |
| Martín de Vidales, C; Pérez-Torrubia, A; Zapatero, A | 1 |
| Bryant, M; Bulun, SE; Hsu, WT; Neely, K; Schultz, RA; Sebastian, S; Shozu, M; Takayama, K | 1 |
| Miyoshi, Y; Noguchi, S; Taguchi, T; Tamaki, Y | 1 |
| Okamura, Y; Sakurai, T; Shimizu, Y; Suzuma, T; Umemura, T; Yang, QF; Yoshimura, G | 1 |
| Campos, SM; Winer, EP | 1 |
| Gertler, SZ; Mauriac, L; Osborne, CK; Pippen, JE; Quaresma Albano, J | 1 |
| Brown, P; Wu, K | 1 |
| Dranitsaris, G; Trudeau, M; Verma, S | 1 |
| Casanovas, J; Milla, L; Milla-Santos, A; Pons, M; Portella, J; Puig-Gali, M; Rallo, L; Rodes, E | 1 |
| Dimmer, C; Goodare, H; Page, K | 1 |
| Burton, G; Kleeberg, U; Mauriac, L; Osborne, CK; Robertson, JF; Vergote, I | 1 |
| Höffken, K; Sayer, HG | 1 |
| Buzdar, A; Come, SE; Ellis, M; Gertler, S; Howell, A; Jones, SE; Kleeberg, UR; Mauriac, L; Morris, C; Osborne, CK; Robertson, JF; Vergote, I; Webster, A | 1 |
| Baum, M; Buzdar, A | 1 |
| Rocchi, A; Verma, S | 2 |
| Bonneterre, J; Buzdar, A; Nabholtz, JM; Robertson, JF; Thürlimann, B | 2 |
| Rose, C | 2 |
| Brodie, AH; Mouridsen, HT | 1 |
| Thomas, R | 1 |
| Cuzick, J | 5 |
| Dixon, JM; Jackson, J; Miller, WR | 1 |
| Cohen, PG; Holbrook, JM | 1 |
| Carlini, P; Cognetti, F; Colella, E; Di Cosimo, S; Fabi, A; Ferretti, G; Frassoldati, A; Papaldo, P; Romiti, A; Ruggeri, EM; Tomao, S; Tonachella, R | 1 |
| Eckhardt, S | 1 |
| BEVERLEY-BURTON, M | 1 |
| MOLTZ, H; ROSENBLUM, LA | 1 |
| Cuzick, J; Forbes, J; Howell, T; O'Neill, C | 1 |
| AKESTER, AR | 1 |
| GOMOT, L; LUTZ-OSTERTAG, Y | 1 |
| BUTLER, DG; HOLMES, WN; PHILLIPS, JG | 1 |
| Hazini, A; Pietropaolo, M; Repetto, L; Rosso, R; Sestini, A; Vannozzi, O | 1 |
| Lønning, P; Martoni, A; Pfister, C; Zamagni, C | 1 |
| Gershanovich, M; Mouridsen, H | 1 |
| Kmietowicz, Z | 1 |
| Aapro, MS; Forbes, JF | 1 |
| Carlson, RW; Henderson, IC | 1 |
| Hortobagyi, GN | 1 |
| Baird, A; Bross, PF; Chen, G; Jee, JM; Lostritto, RT; Morse, DE; Pazdur, R; Rahman, A; Rosario, LA; Williams, G; Williams, GM; Yang, P | 1 |
| Ben Ayed, F; Burdette-Radoux, S; Caicedo, JJ; Chaudri-Ross, HA; Davidson, N; Gershanovich, M; Gervasio, H; Johnson, S; Lang, R; Manikhas, G; Pluzanska, A; Rose, C; Thomas, R; Vtoraya, O | 1 |
| Gerber, B | 1 |
| Fleming, GF | 1 |
| Baum, M; Buzdar, A; Cuzick, J; Forbes, J; Houghton, J; Howell, A; Sahmoud, T | 1 |
| Dawood, T; Komesaroff, P; Lew, R; Sudhir, K; Williams, M | 1 |
| Baum, M; Buzdar, A; Howell, A | 1 |
| Geisler, J | 2 |
| Dixon, JM; Jackson, J; Miller, WR; Renshaw, L | 1 |
| Nabholtz, JM | 2 |
| Fallowfield, L; Howell, T; Jenkins, V; Shilling, V | 1 |
| Davidson, NE; Emens, L; Visvanathan, K | 1 |
| Pritchard, KI | 1 |
| Brodie, AH; Mouridsen, HT; Rose, C; Smith, IE | 1 |
| Bianco, AR; Clack, G; Coibion, M; Cuzick, J; Duffy, S; Jackson, TL; Lansdown, M; Philips, K; Pollard, S; Wells, M | 1 |
| Campos, S; del Carmen, MG; Duska, LR; Fuller, AF; Goodman, A; Horick, NK; Matulonis, U; Penson, R; Roche, M; Seiden, MV | 1 |
| Gezgin, T; Gul, N; Ozer, S; Soysal, ME; Soysal, S | 1 |
| Buzdar, A; Jones, D; Simons, WR | 1 |
| Howell, A; Robertson, JF; Vergote, I | 1 |
| Howell, A; Mauriac, L; Osborne, CK | 1 |
| Goss, PE; Strasser-Weippl, K | 1 |
| Fallowfield, L; Howell, A; Hutton, S; Jenkins, V; Shilling, V | 1 |
| Aihara, T; Morino, H; Munakata, S; Takatsuka, Y | 1 |
| Cheung, KL; Forward, DP; Jackson, L; Robertson, JF | 1 |
| KOMIYA, Y; KONDO, S | 1 |
| Morgentaler, A; Rhoden, EL | 1 |
| Kammerer, S | 1 |
| Eiermann, W | 1 |
| Domont, J; Khayat, D; Namer, M; Spano, JP | 1 |
| Wilkinson, K | 1 |
| Kawakami, M; Saji, S; Toi, M | 1 |
| Gallo, J; Leder, BZ; Longcope, C; Rohrer, JL; Rubin, SD | 1 |
| Curran, MP; McKeage, K; Plosker, GL | 1 |
| Baron, M; d'Anjou, J; Dessogne, P | 1 |
| Campos, SM | 1 |
| Arora, A; Potter, JF | 1 |
| Baum, M; Bianco, R; Buzdar, A; Coleman, R; Constenla, M; Cuzick, J; Distler, W; Dowsett, M; Forbes, J; Guastalla, JP; Houghton, J; Howell, A; Locker, G; MacKey, J; Sainsbury, R; Tobias, J; Williams, N | 1 |
| Chaudri-Ross, HA; Mouridsen, HT | 1 |
| Guo, KJ; Guo, Y; Huang, L; Li, X; Tong, XG | 1 |
| Aebi, S; Ballabeni, P; Goldhirsch, A; Hess, D; Köberle, D; Pagani, O; Perey, L; Rochlitz, C; Senn, I; Thürlimann, B | 1 |
| Shippen, ER; West, WJ | 1 |
| Al-Hadithi, N; Al-Omari, WR; Sulaiman, WR | 1 |
| Clemons, M; Coleman, RE; Verma, S | 1 |
| Sainsbury, R | 1 |
| Aglietta, M; Cirillo, S; Gatti, M; Martincich, L; Montemurro, F; Regge, D; Russo, F | 1 |
| Christopoulos, S; Rivera, JA; Small, D; Trifiro, M | 1 |
| Aebi, S; Baumann, ChK | 1 |
| Baus, I; Krone, N; Partsch, CJ; Riepe, FG; Sippell, WG; Wiest, S | 1 |
| Howell, A; Tobias, JS | 1 |
| Blanchard, R; Hamid, AM; Leiser, AL | 1 |
| Cuzick, J; Locker, GY; Sainsbury, JR | 1 |
| Tobias, JS | 2 |
| Boccardo, F | 2 |
| Amezcua, C; Bahador, A; Burnett, AF | 1 |
| Megahed, M; Reifenberger, J; Schulte, KW; Sonntag, M | 1 |
| Backeljauw, PF; Bercu, BB; Desrochers, PE; Diamond, FB; Jou, HC; Plourde, PV; Reiter, EO; Rubin, SD | 1 |
| Hillner, BE | 1 |
| Altundag, K; Buzdar, AU; Hortobagyi, G; Morandi, P; Rouzier, R; Theriault, RL | 1 |
| Abou-Jawde, RM; Alemany, CA; Budd, GT; Choueiri, TK | 1 |
| Bloomfield, D; Godward, S; Makris, A; Moody, AM; Thomas, R; Williams, M | 1 |
| Ameye, L; Carbonez, A; Christiaens, MR; Morales, L; Neven, P; Paridaens, R; Timmerman, D; Van Huffel, S; Van Limbergen, E; Vergote, I | 1 |
| Hirono, M; Ikeda, M; Kurebayashi, J; Nakashima, K; Nomura, T; Okubo, S; Sonoo, H; Tanaka, K; Udagawa, K | 1 |
| Fuchimoto, S; Inagaki, M; Miyoshi, K; Nakagawa, T; Ohsaki, T; Ohtsuka, S; Yumura, M | 1 |
| Bianco, AR; Clack, G; Coibion, M; Duffy, S; Jackson, TL; Lansdown, M; Philips, K; Pollard, S; Wells, M | 2 |
| Cella, D; Cuzick, J; Fallowfield, L; Francis, S; Howell, A; Locker, G | 1 |
| Caruggi, M; Colombo, G; Marchetti, M | 1 |
| Hiura, M; Nogawa, T; Oshita, T; Yokoyama, T | 1 |
| Johnston, S; Stebbing, J | 1 |
| Bessho, T; Hirai, I; Kinoshita, T; Kokawa, Y; Nishida, M; Nishimura, O; Okamura, Y; Oura, S; Sakurai, T; Sasaki, R; Tanino, H; Yokochi, H; Yoshimas, T | 1 |
| Anderson, TJ; Cameron, DA; Dixon, JM; Dowsett, M; Hills, M; Jackson, J; Miller, WR; Renshaw, L | 1 |
| Cheng, CW; Cheung, MN; Chow, LW; Loo, WT; Tse, EY | 1 |
| Casper, RF; Diamond, MP; Mitwally, MF | 1 |
| Buraglio, M; Denton, G; Hemsey, G; Tredway, DR | 1 |
| Duffy, SR; Taylor, L | 1 |
| Bajetta, E; Bombardieri, E; Del Vecchio, M; Ferrari, L; La Torre, I; Longarini, R; Martinetti, A; Paleari, D; Seregni, E; Toffolatti, L; Zilembo, N | 1 |
| Buzdar, A; Macahilig, C | 1 |
| de Cremoux, P; Diéras, V; Fourquet, A; Magdelénat, H; Pierga, JY; Poupon, MF; Sigal-Zafrani, B | 1 |
| Harwood, KV | 1 |
| Klein, KO; Mauras, N; Rini, A; Welch, S | 1 |
| Fentiman, IS | 1 |
| Agorastos, T; Bontis, JN; Efstathiadis, E; Pantazis, K; Vaitsi, V; Vavilis, D | 1 |
| Travis, K | 1 |
| Barlow, DH; Kennedy, S | 1 |
| Ahmed, S; Amory, JK; Bremner, W; Cherrier, MM; Craft, S; Johnson, M; Matsumoto, AM; Peskind, ER; Raskind, MA | 1 |
| Dougherty, RH; Hayden, D; Leder, BZ; Rohrer, JL; Rubin, SD | 1 |
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| Ashworth, A; Dexter, T; Dixon, JM; Dowsett, M; Drury, S; Evans, DB; Fenwick, K; Larionov, A; Mackay, A; Miller, WR; Urruticoechea, A; White, S; Young, O | 1 |
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| Brodie, A; Goloubeva, OG; Macedo, LF; Sabnis, GJ | 1 |
| A'hern, R; Banerjee, S; Dowsett, M; Ghazoui, Z; Martin, LA; Pancholi, S; Smith, IE | 1 |
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| Fields, MM; Mellington, TE | 1 |
| Gligorov, J; Nabholtz, JM | 1 |
| Andersen, AN; Andersen, CY; Bangsbøll, S; Freiesleben, NL; Loft, A; Lossl, K | 1 |
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| Brown, JE; Coleman, RE; Dodwell, D; Ellis, SP; Gutcher, SA; Hannon, RA; Horsman, JM; Lester, JE; Purohit, OP; Thorpe, R | 1 |
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| Brodie, A; Macedo, LF; Sabnis, G | 1 |
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| Al-Sukhun, S; Chollet, P; Durando, X; Ferriere, JP; Mouret-Reynier, MA; Nabholtz, JM; Van Praagh, I | 1 |
| Chen, Y; Gonzalez-Angulo, A; Guggisberg, N; Hennessy, B; Jorda, M; Mills, GB; Slingerland, JM; Tan, CK | 1 |
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| Ando, M; Baba, S; Dokiya, F; Douchi, T; Kosha, S; Matsuyama, Y; Ohi, Y; Rai, Y; Sagara, Y; Tamada, S | 1 |
| Fischgräbe, J; Götte, M; Kiesel, L; Radke, I; Smollich, M; Wülfing, P | 1 |
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| Bachleitner-Hofmann, T; Blaha, P; Dubsky, P; Fitzal, F; Gnant, M; Jakesz, R; Steger, G | 1 |
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| A'hern, R; Anderson, H; Crowder, RJ; Dowsett, M; Dunbier, AK; Ellis, MJ; Folkerd, EJ; Ghazoui, Z; Hoog, J; Nerurkar, A; Osin, P; Parker, JS; Perou, CM; Smith, IE | 1 |
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| Anderson, E; Arena, FP; Bacus, S; Cora, EM; Cristofanilli, M; Curcio, E; Kroener, JF; Magill, PJ; Mangalik, A; Rabinowitz, I; Royce, M; Valero, V; Watkins, C | 1 |
| Bowers, CY; Iranmanesh, A; Veldhuis, JD | 1 |
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| Ikeda, Y; Kawana, K; Kozuma, S; Nakagawa, S; Oda, K; Shoji, K; Takazawa, Y; Taketani, Y; Yasugi, T | 1 |
| Fadeeva, EP; Fedosenko, KV; Lisianskaia, AS; Manikhas, GM; Tapil'skaia, NI | 1 |
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| Beckmann, MW; Benedict, A; Buchholz, S; Distler, W; Hadji, P; Harbeck, N; Jonat, W; Kaufmann, M; Kreienberg, R; Kreif, N; Lux, MP; Possinger, K; Raab, G; Schneeweiss, A; Tesch, H; Weyers, G; Wöckel, A | 1 |
| Abe, H; Aihara, T; Aogi, K; Hisamatsu, K; Hozumi, Y; Imoto, S; Ito, T; Iwata, H; Masuda, N; Mitsuyama, S; Mukai, H; Nakagami, K; Ogino, N; Ohashi, Y; Ohsumi, S; Shimizu, C; Takatsuka, Y; Tamura, M; Tanaka, S; Watanabe, T; Yamaguchi, T | 1 |
| Antonopoulou, Z; Dafni, U; Gogas, H; Kalogerakos, K; Koukouras, D; Lazarou, S; Markopoulos, C; Misitzis, J; Papadiamantis, J; Polychronis, A; Sarantopoulou, A; Siasos, N; Tzoracoleftherakis, E; Venizelos, B; Xepapadakis, G; Zobolas, V | 1 |
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| Beckmann, MW; Gnant, M; Jonat, W; Kreienberg, R; Lux, MP; Reichelt, C; Thiel, FC; Wallwiener, D | 1 |
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| Bender, C; Blair-Belansky, H; Moore, PJ; Terhorst, L | 1 |
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| Batzler, A; Chapman, JA; Ellis, MJ; Flockhart, DA; Goetz, MP; Goss, PE; Ingle, JN; Jenkins, GD; Kubo, M; Liu, M; Mushiroda, T; Nakamura, Y; Pater, J; Pritchard, KI; Rohrer, DC; Schaid, DJ; Shepherd, L; Stearns, V; Wang, L; Weinshilboum, RM | 1 |
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| Kawachi, H; Kubota, K; Kuwayama, T; Nakagawa, T; Oda, G; Sato, T; Sugihara, K; Yamamoto, K | 1 |
| Christiaens, MR; De Smet, L; Dieudonné, AS; Henry, NL; Leunen, K; Lintermans, A; Morales, L; Neven, P; Pans, S; Paridaens, R; Timmerman, D; Van Calster, B; Van Hoydonck, M; Vergote, I; Verhaeghe, J; Verschueren, K; Westhovens, R; Wildiers, H | 1 |
| Inaji, H; Ishitobi, M; Komoike, Y; Koyama, H; Motomura, K; Nakahara, S | 1 |
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| Cuzick, J; Dowsett, M; Forbes, JF; Harvie, M; Howell, A; Sestak, I | 1 |
| Dowsett, M; Dunbier, A; Ghazoui, Z; Martin, LA; Pancholi, S; Weigel, MT | 1 |
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| Cunningham, DE; Dacic, S; Keohavong, P; Land, SR; Rothstein, ME; Siegfried, JM; Stabile, LP | 1 |
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| Hayashi, N; Iwase, H; Iwata, H; Kamigaki, S; Kinoshita, T; Masuda, N; Nakamura, S; Nishimura, R; Noguchi, S; Sagara, Y; Takei, H; Tsuda, H; Yanagita, Y | 1 |
| Chen, Z; Li, Z; Liao, M; Lu, S; Niu, X; Shen, L; Shen, S; Yu, Y | 1 |
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| Dean, A; Dewar, J; Ellis, MJ; Emerson, L; Feltl, D; Lindemann, JP; Llombart-Cussac, A; Robertson, JF; Rolski, J | 1 |
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| Channon, E; Dixon, JM; Ellis, IO; Gee, JM; Hyman-Taylor, P; Jahan, A; Nicholson, RI; Robertson, JF; Sibbering, DM | 1 |
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| Hashigaki, S; Hiraoka, M; Iwata, H; Masuda, N; Morimoto, T; Nishizawa, Y; Noguchi, S; Ohno, S; Ohsumi, S; Rai, Y; Saeki, T; Sasano, H; Sato, Y | 1 |
| Hamilton, J; Kamiya-Matsuoka, C; Kumar, VA; Kurzrock, R; Langford, LA; Moulder, S; Munoz, J; Pasche, LJ; Taggart, MW; Tummala, S | 1 |
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| Cowens, JW; Cuzick, J; Dowsett, M; Dunbier, AK; Ferree, S; Lopez-Knowles, E; Schaper, C; Sestak, I; Sidhu, K; Storhoff, J | 1 |
| Bolyakov, A; Mehta, A; Paduch, DA; Roosma, J; Schlegel, PN | 1 |
| Afentakis, M; Buzdar, A; Cuzick, J; Dowsett, M; Forbes, J; Howell, T; Salter, J; Sestak, I | 1 |
| Cataldo, C; D'Andrea, F; De Francesco, F; del Giudice, EM; Di Grezia, G; Ferraro, GA; Gatta, G; Grandone, A; Nicoletti, G; Perrone, L; Romano, T | 1 |
| Balic, M; Dubsky, P; Fesl, C; Fitzal, F; Gnant, M; Greil, R; Jakesz, R; Kwasny, W; Mlineritsch, B; Pfeiler, G; Samonigg, H; Seifert, M; Steger, G; Stierer, M; Stöger, H | 1 |
| Kumar, A; Sawant, KK | 1 |
| Bliss, JM; Braybrooke, JP; Brunt, AM; Cameron, D; Cheung, KL; Coombes, G; Dodwell, D; Dowsett, M; Ellis, P; Folkerd, E; Hayward, L; Howell, A; Im, YH; Johnston, SR; Jyothirmayi, R; Kilburn, LS; Robinson, A; Sergenson, N; Sin, HJ; Wardley, AM; Wheatley, D | 1 |
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| Dowsett, M; Gao, Q; Garcia-Murillas, I; López-Knowles, E; Martin, LA; Segal, CV; Smith, I; Turner, NC | 1 |
| Coonahan, E; Giangregorio, R; Kaplan, DL; Lovett, ML; Yucel, T | 1 |
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| Budd, GT; Chapman, JA; Ellis, MJ; Goss, PE; Ingle, JN; Kundapur, J; Le Maitre, A; Liedke, PE; Ma, CX; Pritchard, KI; Rabaglio, M; Shepherd, LE; Sledge, GW; Stearns, V | 1 |
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| Ahrendt, GM; Bender, CM; Berga, SL; Brufsky, AM; Casillo, FE; Dailey, MM; Erickson, KI; Gentry, AL; Kratofil, FM; McAuliffe, PF; Merriman, JD; Rosenzweig, MQ; Ryan, CM; Sereika, SM | 1 |
| Balic, M; Cowens, JW; Cuzick, J; Dowsett, M; Dubsky, P; Ferree, S; Fesl, C; Filipits, M; Gnant, M; Greil, R; Jakesz, R; Lopez-Knowles, E; Nielsen, T; Rudas, M; Schaper, C; Sestak, I; Stoeger, H | 1 |
| Biggers, A; Charlson, JA; Kamaraju, S; Laud, PW; Neuner, JM; Pezzin, LE; Smallwood, AJ; Smith, EC; Wozniak, EM | 1 |
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| Deshpande, PB; Kumar, AR; Maliyakkal, N; Nayak, UY; Raghavendra, R; Reddya, MS; Shavi, GV; Shrawan, B; Udupa, N | 1 |
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| Dermitzaki, E; Papadimitriou, A; Papadimitriou, DT; Papaevangelou, V; Papagianni, M; Papaioannou, G | 1 |
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| Albain, KS; Brufsky, AM; Cecchini, RS; Cianfrocca, ME; Costantino, JP; Fehrenbacher, L; Ganz, PA; Gross, HM; Hopkins, JO; Julian, TB; Mamounas, EP; Margolese, RG; Seay, TE; Soori, GS; Sturtz, K; Vallow, LA; Whitworth, PW; Wolmark, N; Wozniak, TF | 2 |
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| Alran, S; Balleyguier, C; Becette, V; Bourgier, C; Boussion, V; Cherel, P; Kerbrat, P; Lavau-Denes, S; Lemonnier, J; Lerebours, F; Martin, AL; Mathieu, MC; Mouret-Fourme, E; Mouret-Reynier, MA; Nabholz, JM; Rivera, S; Salmon, R; Sigal, B; Thibault, F; Trassard, M; Venat-Bouvet, L | 1 |
| Gilarranz, YJ; Lopez-Tarruella, S; Martin, M | 1 |
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| Bondarenko, IM; Cardona-Huerta, S; Cheung, KL; Dvorkin, M; Ellis, MJ; Fazal, M; Grinsted, LM; Manikhas, A; Noguchi, S; Panasci, L; Philco-Salas, MJ; Robertson, JFR; Rowbottom, J; Ruiz-Borrego, M; Shao, Z; Shparyk, Y; Stuart, M; Trishkina, E | 1 |
| Nave, R; Ploeger, BA; Reinecke, I; Schmitz, H; Schultze-Mosgau, MH | 1 |
| Guo, W; Huang, XH; Liang, RH; Su, L; Wang, CJ | 1 |
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| Allred, DC; Babiera, G; Barnes, M; Brink, A; Budd, GT; Carey, L; Creighton, CJ; Crouch, E; Dayao, Z; DeSchryver, K; Dowsett, M; Ellis, MJ; Esserman, L; Goncalves, R; Guenther, JM; Hoog, J; Hunt, K; Leitch, M; Luo, J; Ma, CX; Olson, JA; Ota, D; Pluard, T; Sanati, S; Silverman, P; Suman, VJ; Tao, Y; Unzeitig, G; Watson, M; Whitworth, P; Winer, E | 1 |
| Bender, CM; Brufsky, AM; Clark, BZ; Conley, YP; Ghotkar, P; Jankowitz, RC; Koleck, TA; McAuliffe, PF; Ryan, CM; Sereika, SM | 1 |
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| Dattani, M; Hawton, K; Raine, J; Rumsby, G; Walton-Betancourth, S | 1 |
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| Alencar, AP; Andrade, DB; Barros-Oliveira, MDC; Borges, RS; Borges, US; Costa-Silva, DR; da Silva, BB; Lopes-Costa, PV; Silva, VC | 1 |
| Alvarez, CA; Balasubramian, BA; Jean, GW; Murphy, CC; Tiro, JA | 1 |
| Beer, B; Czech, T; Daniaux, M; Holzner, B; Hubalek, M; Kemmler, G; Meraner, V; Oberacher, H; Oberguggenberger, A; Sperner-Unterweger, B; Sztankay, M; Weigel, G; Wildt, L | 1 |
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| Abd-Allateef, M; El-Hiti, GA; Hassan, F; Yousif, E | 1 |
| Averineni, RK; Danilenkoff, C; Deshpande, PB; Ginjupalli, K; Nayak, UY; Raghavendra, R; Reddy, MS; Sadhu, SS; Shavi, GV; Udupa, N | 1 |
| Pan, W; Sun, X; Tang, X; Wu, S; Yang, Y | 1 |
| Ali, SM; Budd, GT; Chapman, JW; Elliott, CR; Ellis, MJ; Garg, A; Goss, PE; Han, L; Ingle, JN; Leitzel, K; Lipton, A; Pritchard, KI; Rabaglio, M; Shepherd, LE; Sledge, GW | 1 |
| Ahmed, I; Bartlett, JMS; Brookes, CL; Cuzick, J; Dell'Orto, P; Dowsett, M; Forbes, JF; Mallon, EA; Putter, H; Rea, DW; Regan, MM; Sestak, I; Seynaeve, C; Thürlimann, B; Van de Velde, CJH; Viale, G | 1 |
| Beale, PJ; Bonaventura, A; DeFazio, A; Friedlander, ML; Goh, JCH; Grant, PT; Hadley, AM; Mapagu, C; Martyn, J; McNally, OM; Mileshkin, LR; OʼConnell, RL; Scurry, J; Sjoquist, KM | 1 |
| Hambly, R; Lally, A | 1 |
| Baj, F; Baravalle, R; Ciaramella, A; Di Nardo, G; Gilardi, G | 1 |
| Andrade, DB; Barros-Oliveira, MDC; Borges, RS; Borges, US; Costa-Silva, DR; Silva, BBD; Silva, JM; Tavares, CB | 1 |
| Hong, N; Kim, SI; Park, S; Rhee, Y; Seo, DH; Sohn, JH; Yoon, HG | 1 |
| Ding, H; Fang, L; Huang, P; Tong, Y; Xin, W; Zhou, Q | 1 |
| Chen, T; Chu, F; Gong, Y; Lei, H; Liu, X; Lu, F; Xing, Y; Xu, B; Yan, M | 1 |
| Eswaran, S; Ghoulam, E; Jakate, S; Klapko, O; Usha, L | 1 |
| Armstrong, DK; Bergstrom, J; DeBernardo, R; Fader, AN; Gaillard, S; Jernigan, A; Levinson, KL; Michener, C; Ricci, S; Roche, KL; Rose, PG; Shih, IM; Stone, RL; Tanner, EJ; Wang, TL; Wethingon, S; Yang, B; Zhang, G | 1 |
| Austin, ED; Brittain, EL; Chen, X; Farber-Eger, EH; Fessel, JP; Hemnes, AR; Loyd, JE; Talati, M; West, J | 1 |
| Chang, X; Höchel, J; Klein, S; Müller, A; Nave, R | 1 |
| He, Y; Huang, Y; Wang, C; Wu, K; Zhang, J; Zheng, S | 1 |
| Cuzick, J; Dowsett, M; Heindl, A; Naidoo, K; Sestak, I; Yuan, Y | 1 |
| Chen, X; Gu, L; Guo, P; Lv, M; Sun, X; Wang, B; Wang, S; Zhao, S | 1 |
| Baravalle, R; Catucci, G; Ciaramella, A; Cimicata, G; Dell'Angelo, V; Di Nardo, G; Gilardi, G; Ugliengo, P | 1 |
| Barriga, S; Bourayou, N; Campone, M; Chen, SC; Di Leo, A; Forrester, T; Freedman, OC; Frenzel, M; Garnica Jaliffe, G; Goetz, MP; Huober, J; Manso, L; Paluch-Shimon, S; Park, IH; Smith, IC; Sohn, J; Toi, M; Trédan, O | 1 |
| Brasil, OFM; Correa de Mello, P | 1 |
| de Boer, M; De Graaf, H; de Roos, WK; Erdkamp, FLG; Honkoop, AH; Imholz, ALT; Kroep, JR; Linn, SC; Peer, PGM; Seynaeve, CM; Smorenburg, CH; Swinkels, ACP; Tjan-Heijnen, VCG; van den Berkmortel, FWPJ; van der Sangen, MJC; van Hellemond, IEG | 1 |
| Vohora, D; Zameer, S | 1 |
| Fujii, H; Hojo, T; Hosoya, T; Inano, A; Ishii, A; Kataoka, M; Kusuhara, H; Sugiyama, Y; Takahashi, K; Takashima, T; Tanaka, M; Tazawa, S; Tokai, H; Watanabe, Y; Yamashita, S; Yano, T; Yoshida, S | 1 |
| Barnes, KM; Bryant, JC; Cutler, GB; Flor, AC; Jones, JV; Leschek, EW | 1 |
| Chen, BE; Goss, PE; Liedke, PER; O'Shaughnessy, J; Parulekar, WR; Ramjeesingh, R; Shepherd, LE; Strasser-Weippl, K; Sudan, G | 1 |
| Alaamery, M; Alghamdi, B; Almutairi, MS; Alomran, N; Alyafee, YA; Bawazeer, S; Daghestani, M; Massadeh, S; Sheereen, A | 1 |
| Asano, Y; Goto, W; Hatano, T; Hirakawa, K; Kashiwagi, S; Motomura, H; Noda, S; Ohira, M; Onoda, N; Takada, K; Takashima, T; Tsujio, G | 1 |
| Akami, T; Hatakeyama, T; Matsumura, A; Mugitani, T; Ogino, S; Okano, S; Sakai, T | 1 |
| Ellis, MJ; Fazal, M; Noguchi, S; Robertson, JFR; Shao, Z; Thirlwell, J | 1 |
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| Chen, XY; Cheng, DX; Dai, XJ; Li, J; Ma, XF; Shi, CT; Wu, YQ; Zhang, YF; Zhong, DF | 1 |
| Akiyoshi, T; Kuwamura, T; Murakami, S; Ogasa, Y; Suematsu, F; Tanaka, H; Umeda, S | 1 |
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| Chen, Y; Ding, S; Liu, S; Peng, Y; Zheng, J | 1 |
| Abadie-Lacourtoisie, S; Bazan, F; Chabaud, S; Colombe-Vermorel, A; Coquan, E; Dalban, C; Diaz, JJ; Fabbro, M; Frenel, JS; Garin, G; Heudel, PE; Marcel, V; Martinez, S; Mourksi, NE; Odeyer, L; Pérol, D; Ray-Coquard, I; Simioni, V; Tabone-Eglinger, S; Treilleux, I | 1 |
| Egawa, C; Hasegawa, Y; Higaki, K; Hozumi, Y; Iijima, K; Iwase, T; Komoike, Y; Masuoka, H; Mukai, H; Nakamura, T; Ohtani, S; Ohtsu, H; Saji, S; Sato, Y; Takei, H; Tanabe, M; Tanaka, M; Yanagita, Y | 1 |
| Albain, KS; Barlow, WE; Dakhil, SR; Gersch, CL; Gralow, JR; Hayes, DF; Henderson, NC; Henry, NL; Hertz, DL; Hortobagyi, GN; Kidwell, KM; Medley, S; Mehta, RS; Pusztai, L; Rae, JM; Rutherford, DV; Tirumali, NR; Vandenberg, TA | 1 |
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269 review(s) available for anastrozole and triazoles
| Article | Year |
|---|---|
ARIMIDEX: a new oral, once-a-day aromatase inhibitor.
Topics: Administration, Oral; Aldosterone; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estradiol; Female; Humans; Hydrocortisone; Nitriles; Triazoles | 1995 |
New aromatase inhibitors for breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 1997 |
Vorozole.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 1997 |
ARIMIDEX: a potent and selective aromatase inhibitor for the treatment of advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Triazoles | 1997 |
Use of aromatase inhibitors in postmenopausal women with advanced breast cancer.
Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles | 1997 |
Anastrozole: a new selective nonsteroidal aromatase inhibitor.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Nitriles; Postmenopause; Safety; Survival Rate; Treatment Outcome; Triazoles; United States | 1997 |
The relevance of preclinical models to the treatment of postmenopausal breast cancer.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Mammary Neoplasms, Experimental; Nitriles; Postmenopause; Rats; Triazoles | 1997 |
Anastrozole--a new generation in aromatase inhibition: clinical pharmacology.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Nitriles; Triazoles | 1997 |
Clinical overview of anastrozole--a new selective oral aromatase inhibitor.
Topics: Administration, Oral; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Megestrol Acetate; Nitriles; Postmenopause; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 1997 |
Anastrozole: a selective aromatase inhibitor for the treatment of breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Nitriles; Triazoles | 1998 |
Anastrozole: a new addition to the armamentarium against advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Tamoxifen; Triazoles | 1998 |
Emerging role of aromatase inhibitors in the treatment of breast cancer.
Topics: Aged; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 1998 |
Anastrozole (Arimidex), a new aromatase inhibitor for advanced breast cancer: mechanism of action and role in management.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Nitriles; Triazoles | 1998 |
Theoretical considerations for the ideal aromatase inhibitor.
Topics: Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 1998 |
Pharmacological and clinical profile of anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Humans; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 1998 |
Anastrozole. A review of its use in the management of postmenopausal women with advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Neoplasm Staging; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 1998 |
The third-generation non-steroidal aromatase inhibitors: a review of their clinical benefits in the second-line hormonal treatment of advanced breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Belgium; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Severity of Illness Index; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 1999 |
New aromatase inhibitors for the treatment of advanced breast cancer in postmenopausal women.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Triazoles | 1999 |
[Aromatase inhibitors].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrone; Female; Humans; Letrozole; Nitriles; Triazoles | 1999 |
Lessons from the use of aromatase inhibitors in the neoadjuvant setting.
Topics: Aged; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 1999 |
Aromatase inhibitors: a dose-response effect?
Topics: Aminoglutethimide; Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrogens; Fadrozole; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 1999 |
Use of aromatase inhibitors in breast carcinoma.
Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Drug Design; Drug Interactions; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Middle Aged; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Premenopause; Tamoxifen; Triazoles | 1999 |
Steroidal aromatase inhibitors in elderly patients.
Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2000 |
Estrogen biosynthesis in endometriosis: molecular basis and clinical relevance.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrogens; Estrone; Female; Humans; Middle Aged; Mullerian Ducts; Nitriles; Pregnancy; Triazoles | 2000 |
[Chemo/endocrine therapy for breast cancer patients].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Gonadotropin-Releasing Hormone; Humans; Nitriles; Tamoxifen; Triazoles | 2000 |
[Aromatase inhibitors for treatment of advanced breast cancers].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Fadrozole; Female; Humans; Letrozole; Nitriles; Treatment Outcome; Triazoles | 2000 |
New aromatase inhibitors in the treatment of advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Multicenter Studies as Topic; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 2000 |
Survival in patients with metastatic breast cancer: analysis of randomized studies comparing oral aromatase inhibitors versus megestrol.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol; Neoplasm Metastasis; Nitriles; Proportional Hazards Models; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles | 2000 |
[Endometriosis and aromatase inhibitor].
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Dinoprostone; Endometriosis; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Fadrozole; Female; Humans; Middle Aged; Nitriles; Triazoles | 2001 |
[Preclinical evaluation of aromatase inhibitors antitumor activity].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Models, Animal; Nitriles; Rats; Structure-Activity Relationship; Triazoles | 2000 |
[Aromatase inhibitors: pharmacological aspects].
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Fadrozole; Female; Humans; Letrozole; Nitriles; Triazoles | 2000 |
[Aromatase inhibitors: a review of clinical trials].
Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 2000 |
[Development of a novel aromatase inhibitor, anastrozole (Arimidex)--its basic and clinical studies].
Topics: Anastrozole; Animals; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase I as Topic; Dogs; Enzyme Inhibitors; Female; Humans; Mice; Middle Aged; Nitriles; Postmenopause; Rats; Triazoles | 2001 |
[Developments of hormonal agents for breast cancer].
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Nitriles; Tamoxifen; Triazoles | 2001 |
Nonsteroidal and steroidal aromatase inhibitors in breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2001 |
Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.
Topics: Anastrozole; Androstadienes; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Fadrozole; Female; Headache; Humans; Letrozole; Nausea; Nitriles; Treatment Outcome; Triazoles; Vomiting | 2001 |
New combinations with Herceptin in metastatic breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclophosphamide; Deoxycytidine; Doxorubicin; Drug Interactions; Drug Synergism; Epirubicin; Female; Fluorouracil; Gemcitabine; Heart Diseases; Hematologic Diseases; Humans; Methotrexate; Neoplasm Metastasis; Nitriles; Organoplatinum Compounds; Paclitaxel; Tamoxifen; Thiotepa; Trastuzumab; Treatment Outcome; Triazoles; Vinblastine; Vinorelbine | 2001 |
Role of anti-aromatase agents in postmenopausal advanced breast cancer.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2001 |
Third-generation aromatase inhibitors in the treatment of advanced breast cancer.
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2001 |
Aromatase and aromatase inhibitors.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Letrozole; Nitriles; Survival Analysis; Treatment Outcome; Triazoles | 2001 |
A summary of second-line randomized studies of aromatase inhibitors.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Enzyme Inhibitors; Estrogen Receptor Modulators; Fadrozole; Female; Humans; Letrozole; Megestrol Acetate; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2001 |
A vision for the future?
Topics: Anastrozole; Breast Neoplasms; Estradiol; Female; Fulvestrant; Goserelin; Humans; Menopause; Nitriles; Tamoxifen; Triazoles | 2001 |
Anastrozole (Arimidex)--an aromatase inhibitor for the adjuvant setting?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Triazoles | 2001 |
Are differences in the available aromatase inhibitors and inactivators significant?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2001 |
Preliminary data from ongoing adjuvant aromatase inhibitor trials.
Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Triazoles | 2001 |
Aromatase inhibitors continue their ATAC on tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2002 |
Antiaromatase agents: evolving role in adjuvant therapy.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2002 |
Aromatase inhibition for ovarian stimulation: future avenues for infertility management.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Drug Administration Schedule; Enzyme Inhibitors; Female; Follicular Phase; Humans; Infertility, Female; Mice; Nitriles; Ovulation Induction; Pregnancy; Triazoles | 2002 |
[The role of aromatase inhibitors in the treatment of breast neoplasms. An evaluation of clinical efficacy and the tolerability profile].
Topics: Adult; Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Follow-Up Studies; Forecasting; Humans; Letrozole; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Triazoles | 2002 |
[Antiestrogen therapy in the treatment of breast neoplasms].
Topics: Adult; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Estrogen Antagonists; Female; Forecasting; Humans; Indoles; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Osteoporosis; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Toremifene; Triazoles | 2002 |
Anastrozole: pharmacological and clinical profile in postmenopausal women with breast cancer.
Topics: Adjuvants, Pharmaceutic; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Female; Follow-Up Studies; Humans; Neoadjuvant Therapy; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Letrozole for the management of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Drug Tolerance; Estrogen Receptor Modulators; Estrogens; Female; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Postmenopause; Progestins; Receptors, Estrogen; Treatment Outcome; Triazoles | 2002 |
Evolving uses of hormonal agents for breast cancer therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Nitriles; Tamoxifen; Toremifene; Triazoles | 2002 |
Recent advances in aromatase inhibitor therapy for breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Premenopause; Triazoles | 2002 |
American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for women with hormone receptor-positive breast cancer: status report 2002.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Enzyme Inhibitors; Evidence-Based Medicine; Expert Testimony; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen; Triazoles | 2002 |
Anastrozole in the management of breast cancer.
Topics: Anastrozole; Animals; Breast Neoplasms; Disease Management; Drug Evaluation; Female; Humans; Nitriles; Survival Analysis; Triazoles | 2002 |
New generation aromatase inhibitors--from the advanced to the adjuvant setting.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2002 |
The evolving role of aromatase inhibitors in breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Humans; Letrozole; Nitriles; Triazoles | 2002 |
An overview of the pharmacology and pharmacokinetics of the newer generation aromatase inhibitors anastrozole, letrozole, and exemestane.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2002 |
Anastrozole: in early breast cancer.
Topics: Administration, Oral; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Therapy, Combination; Enzyme Inhibitors; Female; Half-Life; Humans; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2002 |
Breast cancer chemoprevention--an update.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Forecasting; Genes, BRCA2; Humans; Incidence; Middle Aged; Nitriles; Odds Ratio; Receptors, Estrogen; Tamoxifen; Triazoles | 2002 |
Anastrozole (Arimidex) in clinical practice versus the old 'gold standard', tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Approval; Female; Humans; Nitriles; Tamoxifen; Triazoles; United States | 2002 |
Pharmacology and pharmacokinetics of the newer generation aromatase inhibitors.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Female; Humans; Letrozole; Lipids; Nitriles; Postmenopause; Triazoles | 2003 |
Adjuvant endocrine therapy in postmenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2003 |
Current and future status of adjuvant therapy for breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Clodronic Acid; Female; Forecasting; Humans; Nitriles; Osteoporosis; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Is tamoxifen the Rosetta stone for breast cancer?
Topics: Acetyltransferases; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Controlled Clinical Trials as Topic; Disease-Free Survival; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Histone Acetyltransferases; Humans; Metaphor; Nitriles; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivator 3; Oncogene Proteins; Phosphorylation; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Signal Transduction; Tamoxifen; Trans-Activators; Transcription Factors; Treatment Failure; Treatment Outcome; Triazoles | 2003 |
Aromatase inhibitors as adjuvant therapy in breast cancer.
Topics: Aminoglutethimide; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Nitriles; Triazoles | 2003 |
[Present and future of adjuvant hormone therapy in breast cancer: clinical evidence and clinical trials].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2003 |
Current status of endocrine therapy for breast cancer.
Topics: Algorithms; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemoprevention; Chemotherapy, Adjuvant; Climacteric; Female; Goserelin; Humans; Neoplasm Metastasis; Nitriles; Tamoxifen; Triazoles | 2003 |
Anastrozole as adjuvant therapy for early-stage breast cancer: implications of the ATAC trial.
Topics: Age Factors; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Humans; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors; Treatment Outcome; Triazoles; United States | 2003 |
Hormonal therapy in postmenopausal women with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Humans; Neoadjuvant Therapy; Nitriles; Postmenopause; Progestins; Triazoles | 2003 |
Is low-dose tamoxifen useful for the treatment and prevention of breast cancer?
Topics: Anastrozole; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Estrogen Receptor Modulators; Estrogens; Female; Humans; Ki-67 Antigen; Nitriles; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2003 |
The current status of aromatase inhibitors in the management of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2003 |
A comparison of the efficacy of aromatase inhibitors in second-line treatment of metastatic breast cancer.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Applicability of the intratumor aromatase preclinical model to predict clinical trial results with endocrine therapy.
Topics: Anastrozole; Androstadienes; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Estrogen Antagonists; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Tamoxifen; Triazoles; Xenograft Model Antitumor Assays | 2003 |
Aromatase inhibitors in prevention--data from the ATAC (arimidex, tamoxifen alone or in combination) trial and the design of IBIS-II (the second International Breast Cancer Intervention Study).
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Prognosis; Tamoxifen; Triazoles | 2003 |
Safety issues surrounding the use of aromatase inhibitors in breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Metabolism; Nitriles; Patient Satisfaction; Quality of Life; Safety; Tamoxifen; Triazoles | 2003 |
Should aromatase inhibitors replace tamoxifen?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2003 |
[Perspectives for the hormonal therapy of breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Letrozole; Nitriles; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Toremifene; Triazoles | 2003 |
Pharmacokinetics of third-generation aromatase inhibitors.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Enzyme Inhibitors; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2003 |
The role of aromatase inhibitors in the treatment of metastatic breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2003 |
Three years' follow-up from the ATAC trial is sufficient to change clinical practice: a debate.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Evidence-Based Medicine; Female; Follow-Up Studies; Humans; Middle Aged; Nitriles; Postmenopause; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors; Triazoles | 2003 |
Sequential hormonal therapy for metastatic breast cancer after adjuvant tamoxifen or anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Endocrine System; Female; Humans; Menopause; Neoplasm Metastasis; Nitriles; Patient Selection; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Fulvestrant in postmenopausal women with advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Drug Approval; Estradiol; Female; Fulvestrant; Humans; Nitriles; Postmenopause; Survival Rate; Treatment Outcome; Triazoles; United States; United States Food and Drug Administration | 2003 |
Efficacy of tamoxifen following anastrozole ('Arimidex') compared with anastrozole following tamoxifen as first-line treatment for advanced breast cancer in postmenopausal women.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cross-Over Studies; Double-Blind Method; Female; Humans; Middle Aged; Multicenter Studies as Topic; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Retrospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
[Adjuvant endocrine treatment of breast cancer beyond St. Gallen 2003].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2003 |
Role of anastrozole in adjuvant therapy for postmenopausal patients.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2003 |
Breast cancer tissue estrogens and their manipulation with aromatase inhibitors and inactivators.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Humans; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2003 |
Neoadjuvant tamoxifen and aromatase inhibitors: comparisons and clinical outcomes.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Nitriles; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2003 |
New findings about endocrine therapy for breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2003 |
The best use of adjuvant endocrine treatments.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Female; Gonadotropin-Releasing Hormone; Humans; Middle Aged; Nitriles; Ovary; Receptors, Estrogen; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
Challenges in the endocrine management of breast cancer.
Topics: Adult; Aged; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Letrozole; Mastectomy, Segmental; Mice; Middle Aged; Nitriles; Prognosis; Randomized Controlled Trials as Topic; Receptors, Estrogen; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles; United Kingdom | 2003 |
Aromatase inhibitors in breast cancer therapy.
Topics: Anastrozole; Androstadienes; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Triazoles | 2003 |
Focus on anastrozole and breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Therapy, Combination; Enzyme Inhibitors; Estrogens; Female; Goserelin; Humans; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Triazoles | 2003 |
A review of the efficacy of anastrozole in postmenopausal women with advanced breast cancer with visceral metastases.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Liver Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2003 |
[Neoadjuvant endocrine therapy for breast cancer: an overview].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Tamoxifen; Triazoles | 2004 |
Anastrozole (Arimidex).
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Half-Life; Humans; Metabolic Clearance Rate; Nitriles; Nurse's Role; Oncology Nursing; Patient Education as Topic; Triazoles | 2004 |
[Controversies in endocrine therapy for breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogen Replacement Therapy; Female; Humans; Letrozole; Mastectomy, Segmental; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen; Triazoles | 2004 |
Fulvestrant: a review of its use in hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2004 |
Aromatase inhibitors for breast cancer in postmenopausal women.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2004 |
Aromatase inhibitors: current indications and future prospects for treatment of postmenopausal breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Approval; Drug Interactions; Economics, Pharmaceutical; Female; Forecasting; Geriatrics; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Patient Selection; Postmenopause; Practice Patterns, Physicians'; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles; United States; United States Food and Drug Administration | 2004 |
Aromatase inhibitors in the adjuvant setting: bringing the gold to a standard?
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Aromatase inhibition in the treatment of advanced breast cancer: is there a relationship between potency and clinical efficacy?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2004 |
Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Brachial Plexus Neuropathies; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Gonadotropin-Releasing Hormone; Humans; Leiomyoma; Lung Neoplasms; Magnetic Resonance Imaging; Middle Aged; Neoplasm Invasiveness; Neoplasms; Nitriles; Radiography, Thoracic; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Triazoles; Uterine Neoplasms | 2004 |
[Aromatase inhibitors in the adjuvant therapy of breast carcinomas].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Patient Care Management; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Endocrine approaches for the treatment of early and advanced breast cancer in postmenopausal women.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2004 |
Current developments in hormonal therapy of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2004 |
The ATAC (Arimidex, Tamoxifen, Alone or in Combination) trial: an update.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2004 |
Switching trial of adjuvant tamoxifen with an aromatase inhibitor in postmenopausal patients with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Enzyme Inhibitors; Evidence-Based Medicine; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Triazoles | 2004 |
Role of aromatase inhibitors in the treatment of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2004 |
[Postoperative hormone (endocrine) therapy in endometrial carcinoma].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chemotherapy, Adjuvant; Drug Therapy, Combination; Endometrial Neoplasms; Estrogens; Female; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Medroxyprogesterone Acetate; Nitriles; Postoperative Care; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Recent advances in endocrine therapy for postmenopausal women with early breast cancer: implications for treatment and prevention.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2004 |
Breast cancer (metastatic).
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2003 |
[Tamoxifen and aromatase inhibitors in the treatment of breast cancer in menopausal women: pharmacological and clinical aspects].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Female; Humans; Letrozole; Menopause; Neoplasms, Hormone-Dependent; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2004 |
Advances in endocrine therapy for breast cancer: considering efficacy, safety, and quality of life.
Topics: Algorithms; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Decision Trees; Drug Administration Schedule; Drug Monitoring; Estradiol; Female; Fulvestrant; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Nurse's Role; Oncology Nursing; Patient Education as Topic; Patient Selection; Postmenopause; Quality of Life; Safety; Selective Estrogen Receptor Modulators; Social Support; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Aromatase inhibitors and breast cancer: time for a change?
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Letrozole; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Risk Factors; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Endometriosis: new genetic approaches and therapy.
Topics: Anastrozole; Aromatase Inhibitors; Drug Therapy, Combination; Endometriosis; Endometrium; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Techniques; Gonadotropin-Releasing Hormone; Humans; Long-Term Care; Nitriles; Oligonucleotide Array Sequence Analysis; Triazoles | 2005 |
Endocrine treatment options for advanced breast cancer--the role of fulvestrant.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gefitinib; Humans; Nitriles; Postmenopause; Quinazolines; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Using aromatase inhibitors in the neoadjuvant setting: evolution or revolution?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Evidence-Based Medicine; Female; Humans; Letrozole; Mastectomy, Segmental; Neoadjuvant Therapy; Nitriles; Randomized Controlled Trials as Topic; Receptors, Estrogen; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Clinical applications of hormonal therapy in ovarian cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Clinical Trials, Phase II as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leuprolide; Medroxyprogesterone; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Ovarian Neoplasms; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Adjuvant use of aromatase inhibitors in postmenopausal women with breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2005 |
Aromatase inhibitors in advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 2004 |
Innovations in antineoplastic therapy.
Topics: Adjuvants, Immunologic; Alemtuzumab; Aminoglycosides; Anastrozole; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Benzamides; Bile; Boronic Acids; Bortezomib; Capecitabine; Cetuximab; Decanoic Acids; Deoxycytidine; Docetaxel; Drug Approval; Estradiol; Fluorouracil; Fulvestrant; Gefitinib; Gemtuzumab; Humans; Imatinib Mesylate; Letrozole; Leuprolide; Nitriles; Oligopeptides; Organoplatinum Compounds; Oxaliplatin; Oxides; Piperazines; Polyesters; Pyrazines; Pyrimidines; Quinazolines; Taxoids; Thionucleotides; Tissue Extracts; Triazoles; United States; United States Food and Drug Administration; Vidarabine Phosphate | 2005 |
Preclinical and clinical experience with fulvestrant (Faslodex) in postmenopausal women with hormone receptor-positive advanced breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Dose-Response Relationship, Drug; Estradiol; Female; Fulvestrant; Humans; Immunohistochemistry; Injections, Intramuscular; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2005 |
Aromatase inhibition: translation into a successful therapeutic approach.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogens; Female; Humans; Letrozole; Molecular Structure; Nitriles; Triazoles | 2005 |
Aromatase inhibitors in the treatment of early and advanced breast cancer.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Biopsy, Needle; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Immunohistochemistry; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Survival Rate; Treatment Outcome; Triazoles | 2005 |
Effectiveness and tolerability of fulvestrant in postmenopausal women with hormone receptor-positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Estradiol; Female; Fulvestrant; Humans; Injections, Intramuscular; Neoplasm Staging; Nitriles; Postmenopause; Quality of Life; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Aromatase inhibitors for the treatment and prevention of breast cancer.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Nitriles; Randomized Controlled Trials as Topic; Risk Assessment; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
[Aromatase inhibitors in adjuvant setting in breast cancer].
Topics: Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Menopause; Nitriles; Triazoles | 2004 |
A comparison of fulvestrant and the third-generation aromatase inhibitors in the second-line treatment of postmenopausal women with advanced breast cancer.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2005 |
Aromatase inhibitors for therapy of advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Drug Evaluation; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
The aromatase inhibitors in early breast cancer: who, when, and why?
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Letrozole; Nitriles; Patient Selection; Selective Estrogen Receptor Modulators; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Recurrence; Survival Rate; Tamoxifen; Triazoles | 2005 |
Adjuvant endocrine therapy in postmenopausal women with early breast cancer: where are we now?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2005 |
Safety considerations of adjuvant therapy in early breast cancer in postmenopausal women.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Controlled Clinical Trials as Topic; Estrogen Receptor Modulators; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials.
Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Clinical Trials, Phase III as Topic; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Probability; Prognosis; Remission Induction; Risk Assessment; Survival Analysis; Triazoles | 2005 |
Breast adenocarcinoma metastatic to epidural cervical spine meningioma: case report and review of the literature.
Topics: Adenocarcinoma; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carrier Proteins; Cervical Vertebrae; Female; Fractures, Compression; Glycoproteins; Humans; Immunohistochemistry; Lumbar Vertebrae; Magnetic Resonance Imaging; Membrane Transport Proteins; Meningioma; Middle Aged; Nitriles; Radiography; Spinal Cord Neoplasms; Treatment Outcome; Triazoles | 2005 |
Breast cancer (metastatic).
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Bridged-Ring Compounds; Female; Humans; Nitriles; Progestins; Tamoxifen; Taxoids; Trastuzumab; Triazoles | 2005 |
Recent advances in the use of aromatase inhibitors for women with postmenopausal breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles | 2005 |
Adjuvant endocrine therapy in postmenopausal breast cancer patients.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2005 |
The biology of steroid hormones and endocrine treatment of breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Goserelin; Humans; Nitriles; Postmenopause; Triazoles | 2005 |
New developments in the treatment of postmenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2005 |
Comparative assessment of lipid effects of endocrine therapy for breast cancer: implications for cardiovascular disease prevention in postmenopausal women.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Estradiol; Female; Fulvestrant; Hormone Replacement Therapy; Humans; Lipids; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Risk Factors; Tamoxifen; Triazoles; Triglycerides | 2006 |
Life following aromatase inhibitors--where now for endocrine sequencing?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Nitriles; Triazoles | 2005 |
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Joint Diseases; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2006 |
Defining the roles of aromatase inhibitors in the adjuvant treatment of early-stage breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Neoplasm Staging; Nitriles; Research Design; Tamoxifen; Triazoles | 2005 |
Testotoxicosis: current viewpoint.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Body Height; Child; Clinical Trials, Phase II as Topic; Humans; Male; Nitriles; Point Mutation; Puberty, Precocious; Receptors, LH; Tosyl Compounds; Triazoles | 2005 |
Benefit with aromatase inhibitors in the adjuvant setting for postmenopausal women with breast cancer.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles | 2005 |
Role of anastrozole across the breast cancer continuum: from advanced to early disease and prevention.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Estrogen Receptor Modulators; Female; Humans; Neoadjuvant Therapy; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Triazoles | 2006 |
Adjuvant endocrine therapy for postmenopausal women with early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2006 |
[Precocious puberty].
Topics: Anastrozole; Aromatase Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Gonadotropins, Pituitary; Humans; Leuprolide; Male; Nitriles; Prognosis; Puberty, Precocious; Surgical Procedures, Operative; Triazoles | 2006 |
[Clinical application of the gonadotropin--ovulation induction].
Topics: Anastrozole; Anovulation; Aromatase Inhibitors; Drug Therapy, Combination; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Outcome; Pulse Therapy, Drug; Triazoles | 2006 |
Adjuvant aromatase inhibitor therapy for early breast cancer: A review of the most recent data.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2006 |
Acute bilateral pulmonary emboli occurring while on adjuvant aromatase inhibitor therapy with anastrozole: Case report and review of the literature.
Topics: Acute Disease; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Incidence; Nitriles; Pulmonary Embolism; Triazoles; Venous Thrombosis | 2006 |
Pre-menopausal breast cancer and aromatase inhibitors: Treating a new generation of women.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Therapy; Estrogens; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2006 |
Anastrozole for breast cancer: recent advances and ongoing challenges.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2006 |
The adjuvant endocrine treatment revolution: focus on anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Molecular Structure; Nitriles; Treatment Outcome; Triazoles | 2006 |
Time to response: comparison of fulvestrant and oral endocrine agents.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Injections, Intramuscular; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2006 |
Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.
Topics: Adult; Aged; Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles | 2006 |
Bone safety of aromatase inhibitors versus tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Female; Fractures, Bone; Humans; Letrozole; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2006 |
Update on the use of aromatase inhibitors in breast cancer.
Topics: Anastrozole; Androstadienes; Animals; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 2006 |
Refining the postmenopausal breast cancer treatment paradigm: the FACE trial.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Multicenter Studies as Topic; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 2006 |
Aromatase inhibitors and bone health in women with breast cancer.
Topics: Absorptiometry, Photon; Algorithms; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Remodeling; Breast Neoplasms; Diphosphonates; Female; Fractures, Bone; Humans; Life Style; Neoplasms, Hormone-Dependent; Nitriles; Osteoporosis, Postmenopausal; Population Surveillance; Risk Factors; Triazoles | 2006 |
Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Disease-Free Survival; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles | 2006 |
Adjuvant therapy for patients who have node-positive breast cancer.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Lymphatic Metastasis; Middle Aged; Nitriles; Postmenopause; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
Do endocrine treatments for breast cancer have a negative impact on lipid profiles and cardiovascular risk in postmenopausal women?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Cholesterol; Estrogens; Female; Humans; Nitriles; Postmenopause; Risk Factors; Tamoxifen; Thromboembolism; Triazoles; Triglycerides | 2007 |
Economic evaluation of the prevention and treatment of breast cancer--present status and open issues.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Tamoxifen; Triazoles | 2007 |
Initial versus sequential adjuvant aromatase inhibitor therapy: a review of the current data.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2006 |
Optimizing endocrine therapy for premenopausal and postmenopausal women with breast cancer.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Ovariectomy; Ovary; Postmenopause; Premenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles | 2007 |
[Optimal adjuvant hormone therapy in postmenopausal women with hormone-sensitive mammary carcinoma: tamoxifen and the aromatase inhibitors anastrozole, exemestane and letrozole].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
[Advancement in endocrine therapy for breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2007 |
New advances in ovulation induction.
Topics: Anastrozole; Aromatase Inhibitors; Clomiphene; Estrogen Antagonists; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female; Letrozole; Nitriles; Ovary; Ovulation Induction; Pregnancy; Pregnancy Rate; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Hormonal therapies for early breast cancer: systematic review and economic evaluation.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Drug Administration Schedule; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Survival Analysis; Tamoxifen; Time Factors; Triazoles | 2007 |
Aromatase inhibitors and musculoskeletal pain in patients with breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Monitoring; Female; Humans; Musculoskeletal Diseases; Nitriles; Nurse's Role; Nursing Assessment; Nursing Research; Oncology Nursing; Pain; Pain Management; Pain Measurement; Patient Care Planning; Patient Education as Topic; Patient Selection; Postmenopause; Quality of Life; Receptors, Estrogen; Treatment Outcome; Triazoles | 2007 |
[Antiestrogen treatment in postmenopausal patients with metastatic breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Nitriles; Postmenopause; Prognosis; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Reducing the risk of late recurrence in hormone-responsive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Tamoxifen; Triazoles | 2007 |
The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Chemotherapy, Adjuvant; Drug Resistance; Female; Humans; Letrozole; Musculoskeletal Diseases; Nitriles; Postmenopause; Premenopause; Tamoxifen; Thromboembolism; Triazoles | 2007 |
Safety of aromatase inhibitors in the adjuvant setting.
Topics: Anastrozole; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Causality; Chemotherapy, Adjuvant; Comorbidity; Estrogen Receptor Modulators; Female; Hot Flashes; Humans; Incidence; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Nitriles; Osteoporosis; Rats; Survival Analysis; Tamoxifen; Triazoles | 2007 |
Remission of porphyria cutanea tarda after anastrozole treatment of breast cancer.
Topics: Adenocarcinoma; Adult; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Contraceptives, Oral; Female; Ferritins; Hemochromatosis Protein; Histocompatibility Antigens Class I; Humans; Membrane Proteins; Mutation; Nitriles; Phlebotomy; Porphyria Cutanea Tarda; Triazoles | 2007 |
Reducing the risk for breast cancer recurrence after completion of tamoxifen treatment in postmenopausal women.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Letrozole; Nitriles; Postmenopause; Practice Guidelines as Topic; Quality of Life; Risk Assessment; Secondary Prevention; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Effects of hormonal therapy on cognitive functioning in breast cancer patients: a review of the literature.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cognition; Female; Gonadotropin-Releasing Hormone; Humans; Neuropsychological Tests; Nitriles; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2007 |
Anastrozole for malignant and benign conditions: present applications and future therapeutic integrations.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Nitriles; Triazoles | 2007 |
Effectively nursing patients receiving aromatase inhibitor therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Arthralgia; Atrophy; Breast Neoplasms; Cardiovascular Diseases; Comorbidity; Female; Hot Flashes; Humans; Lubricants; Neoplasm Recurrence, Local; Nitriles; Patient Education as Topic; Quality of Life; Tamoxifen; Triazoles; Vagina; Weight Gain | 2008 |
Aromatase inhibitors in adjuvant therapy for hormone receptor positive breast cancer: a systematic review.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2008 |
The impact of adjuvant endocrine therapy on reducing the risk of distant metastases in hormone-responsive breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Evidence-Based Medicine; Letrozole; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Choosing early adjuvant therapy for postmenopausal women with hormone-sensitive breast cancer: aromatase inhibitors versus tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2008 |
Aromatase inhibitors in early breast-cancer treatment: The story so far.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Triazoles | 2008 |
The role of endocrine therapies in reducing risk of recurrence in postmenopausal women with hormone receptor-positive breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Nurse Clinicians; Nurse Practitioners; Nurse's Role; Oncology Nursing; Patient Education as Topic; Patient Selection; Postmenopause; Receptors, Estrogen; Risk Factors; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2008 |
Neoadjuvant endocrine therapy for breast cancer: past, present and future.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Forecasting; Humans; Letrozole; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Patient Selection; Postmenopause; Tamoxifen; Triazoles | 2008 |
Targeting breast cancer with hormonal treatment options.
Topics: Aftercare; Ambulatory Care; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor Modulators; Humans; Information Services; Internet; Letrozole; Nitriles; Nurse Practitioners; Patient Selection; Postmenopause; Practice Guidelines as Topic; Receptors, Estrogen; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
The emerging role of aromatase inhibitors in the adjuvant management of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Therapy, Combination; Humans; Letrozole; Neoplasm Recurrence, Local; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
Aromatase inhibitors for breast cancer: proven efficacy across the spectrum of disease.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Anastrozole: a review of its use in postmenopausal women with early-stage breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2008 |
[Adjuvant endocrine therapy in postmenopausal hormone-sensitive breast cancer: to start, to switch or to extend?].
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Female; Humans; Letrozole; Lymphatic Metastasis; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Skeletal effects of drugs to treat cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Bone Density; Bone Diseases, Metabolic; Fractures, Bone; Humans; Neoplasms; Nitriles; Triazoles | 2008 |
Review of the ATAC study: tamoxifen versus anastrozole in early-stage breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Breast Neoplasms; Early Diagnosis; Humans; Nitriles; Tamoxifen; Triazoles | 2008 |
Aromatase inhibitors and breast cancer.
Topics: Anastrozole; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Humans; Letrozole; Nitriles; Receptor Cross-Talk; Transplantation, Heterologous; Trastuzumab; Triazoles | 2009 |
Future targets in endometriosis treatment: targeting the endometriotic implant.
Topics: Anastrozole; Angiogenesis Inhibitors; Animals; Aromatase Inhibitors; Clinical Trials as Topic; Endometriosis; Female; Humans; Letrozole; Molecular Structure; Nitriles; Triazoles | 2009 |
[Adjuvant breast cancer treatment with hormono-radiotherapy].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2009 |
Comparative review of anastrozole, letrozole and exemestane in the management of early breast cancer.
Topics: Anastrozole; Androstadienes; Animals; Breast Neoplasms; Disease Management; Early Detection of Cancer; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 2009 |
Medical treatment for rectovaginal endometriosis: what is the evidence?
Topics: Anastrozole; Aromatase Inhibitors; Cohort Studies; Danazol; Endometriosis; Female; Gonadotropin-Releasing Hormone; Humans; Intrauterine Devices; Levonorgestrel; Nitriles; Pain; Patient Preference; Randomized Controlled Trials as Topic; Rectal Diseases; Treatment Outcome; Triazoles; Vaginal Diseases | 2009 |
Breast cancer chemoprevention - a vision not yet realized.
Topics: Anastrozole; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Quality of Life; Raloxifene Hydrochloride; Risk Factors; Tamoxifen; Triazoles | 2009 |
Clinical perspectives on the utility of aromatase inhibitors for the adjuvant treatment of breast cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Secondary Prevention; Survival Analysis; Tamoxifen; Triazoles; Women's Health | 2009 |
Exemestane as first-line therapy in postmenopausal women with recurrent or metastatic breast cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Celecoxib; Estrogens; Female; Humans; Letrozole; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Pyrazoles; Randomized Controlled Trials as Topic; Recurrence; Salvage Therapy; Sulfonamides; Tamoxifen; Triazoles | 2010 |
A case of ectopic breast cancer with a literature review.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Choristoma; Female; Humans; Japan; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Staging; Nitriles; Survival Analysis; Treatment Outcome; Triazoles | 2011 |
Aromatase inhibitors for female infertility: a systematic review of the literature.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Female; Fertilization in Vitro; Gonadotropins; Humans; Infant, Newborn; Infertility, Female; Letrozole; Nitriles; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Randomized Controlled Trials as Topic; Triazoles | 2009 |
Clinical use of selective estrogen receptor modulators and down regulators with the main focus on breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Cytochrome P-450 CYP2D6; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Genotype; Humans; Neoadjuvant Therapy; Nitriles; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2009 |
[A negative first-line work-up of Raynaud's phenomenon: And what if it were cancer?].
Topics: Adenocarcinoma, Mucinous; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Combined Modality Therapy; Estrogens; Female; Galantamine; Humans; Mammography; Mastectomy; Neoplasms, Hormone-Dependent; Nitriles; Paraneoplastic Syndromes; Pravastatin; Progesterone; Radiotherapy, Adjuvant; Raynaud Disease; Seasons; Triazoles; Verapamil | 2010 |
[Management of metastatic HER2-positive breast cancer: present and future].
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzoquinones; Bevacizumab; Brain Neoplasms; Breast Neoplasms; Disease Progression; Female; Heart; Humans; Lactams, Macrocyclic; Lapatinib; Letrozole; Neoplasm Proteins; Nitriles; Quinazolines; Quinolines; Receptor, ErbB-2; Trastuzumab; Triazoles | 2010 |
Endometriosis: in search of optimal treatment.
Topics: Adalimumab; Anastrozole; Angiogenesis Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Aromatase Inhibitors; Endometriosis; Estrogen Receptor Modulators; Etanercept; Female; Gonadotropin-Releasing Hormone; Hormone Antagonists; Humans; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Letrozole; Nitriles; Pentoxifylline; Progesterone; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Triazoles; Tumor Necrosis Factor Decoy Receptors; Tumor Necrosis Factor-alpha | 2010 |
Adjuvant endocrine therapy for early breast cancer: the story so far.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles | 2010 |
Question 2. Which medications effectively reduce pubertal gynaecomastia?
Topics: Anastrozole; Aromatase Inhibitors; Child; Estrogen Antagonists; Evidence-Based Medicine; Gynecomastia; Humans; Male; Nitriles; Puberty; Tamoxifen; Treatment Outcome; Triazoles | 2010 |
Systematic review of aromatase inhibitors in the first-line treatment for hormone sensitive advanced or metastatic breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles | 2010 |
Anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Antagonists; Female; Humans; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors; Triazoles | 2010 |
Women and bone health: maximizing the benefits of aromatase inhibitor therapy.
Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Breast Neoplasms; Colorectal Neoplasms; Denosumab; Diphosphonates; Female; Humans; Imidazoles; Letrozole; Nitriles; Osteoporosis; Osteoporosis, Postmenopausal; Randomized Controlled Trials as Topic; RANK Ligand; Secondary Prevention; Tamoxifen; Triazoles; Zoledronic Acid | 2010 |
The efficacy of HER2-targeted agents in metastatic breast cancer: a meta-analysis.
Topics: Anastrozole; Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Female; Fluorouracil; Humans; Lapatinib; Letrozole; Neoplasm Metastasis; Nitriles; Quinazolines; Receptor, ErbB-2; Taxoids; Trastuzumab; Treatment Outcome; Triazoles | 2011 |
When to start an aromatase inhibitor: now or later?
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Drug Administration Schedule; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2011 |
Differences between the non-steroidal aromatase inhibitors anastrozole and letrozole--of clinical importance?
Topics: Anastrozole; Animals; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Cytochrome P-450 CYP2D6; Female; Letrozole; Mice; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2011 |
Overview of adjuvant trials of aromatase inhibitors in early breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles | 2011 |
Preventive therapy for breast cancer: a consensus statement.
Topics: Anastrozole; Androstadienes; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Consensus Development Conferences as Topic; Diphosphonates; Estrogen Receptor Modulators; Expert Testimony; Female; Fenretinide; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metformin; Nitriles; Norpregnenes; Piperidines; Premenopause; Pyrrolidines; Raloxifene Hydrochloride; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen; Tetrahydronaphthalenes; Thiophenes; Triazoles | 2011 |
[Neoadjuvant endocrine therapy for postmenopausal estrogen receptor-positive patients with breast cancer].
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Triazoles | 2011 |
[Aromatase inhibitors and arthralgia].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Letrozole; Medication Adherence; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Risk Factors; Triazoles | 2011 |
The emerging use of aromatase inhibitors for endometriosis treatment.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Endometriosis; Endometrium; Estrogens; Female; Fertility; Humans; Letrozole; Mice; Nitriles; Ovary; Pelvic Pain; Rats; Triazoles | 2011 |
Use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review.
Topics: Anastrozole; Aromatase Inhibitors; Clinical Trials as Topic; Endometriosis; Female; Humans; Letrozole; Nitriles; Pain, Postoperative; Pelvic Pain; Triazoles | 2011 |
Clinical and economic benefits of aromatase inhibitor therapy in early-stage breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Female; Humans; Letrozole; Nitriles; Postmenopause; Survival Analysis; Triazoles | 2011 |
Update on adjuvant hormonal treatment of early breast cancer.
Topics: Administration, Oral; Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2011 |
Management of patients with metastatic breast cancer.
Topics: Adult; Age Factors; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease Management; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Delivery Systems; Estradiol; Female; Fulvestrant; Humans; Letrozole; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Nitriles; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome; Triazoles | 2011 |
Initialization of adjuvant hormonal treatment for breast cancer.
Topics: Adult; Age Factors; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Early Detection of Cancer; Female; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Premenopause; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Lapatinib and trastuzumab in combination with an aromatase inhibitor for the first-line treatment of metastatic hormone receptor-positive breast cancer which over-expresses human epidermal growth factor 2 (HER2): a systematic review and economic analysis.
Topics: Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Lapatinib; Letrozole; Nitriles; Quinazolines; Receptor, ErbB-2; Trastuzumab; Triazoles | 2011 |
Reviewing the cost-effectiveness of endocrine early breast cancer therapies: influence of differences in modeling methods on outcomes.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cost-Benefit Analysis; Female; Humans; Models, Economic; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Tamoxifen; Time Factors; Triazoles | 2012 |
Uterine sarcoma and aromatase inhibitors: Tom Baker Cancer Centre experience and review of the literature.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Female; Humans; Hysterectomy; Leiomyosarcoma; Middle Aged; Nitriles; Retrospective Studies; Sarcoma, Endometrial Stromal; Triazoles; Uterine Neoplasms | 2012 |
Aromatase inhibitors--a viable option for recurrent granulosa cell tumour of ovary: overview and case report.
Topics: Anastrozole; Aromatase Inhibitors; Female; Granulosa Cell Tumor; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Ovarian Neoplasms; Tomography, X-Ray Computed; Triazoles | 2012 |
Soy products in the management of breast cancer.
Topics: Anastrozole; Animals; Aryl Hydrocarbon Hydroxylases; Asian People; Breast Neoplasms; Cytochrome P-450 CYP1B1; Diet; Drug Interactions; Female; Humans; Incidence; Isoflavones; Meta-Analysis as Topic; Nitriles; Polymorphism, Genetic; Prognosis; Proto-Oncogene Proteins c-mdm2; Receptor, ErbB-2; Recurrence; Risk Factors; Soy Foods; Tamoxifen; Triazoles | 2012 |
Aromatase inhibitors in the treatment of elderly women with metastatic breast cancer.
Topics: Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Comorbidity; Disease Management; Disease Progression; Drug Therapy, Combination; Female; Geriatric Assessment; Health Status; Humans; Letrozole; Life Expectancy; Nitriles; Prognosis; Quality of Life; Treatment Outcome; Triazoles | 2013 |
A meta-analysis of anastrozole in combination with fulvestrant in the first line treatment of hormone receptor positive advanced breast cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Treatment Outcome; Triazoles | 2013 |
Pharmacogenomics of endocrine therapy in breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Genome-Wide Association Study; Humans; Japan; Letrozole; Musculoskeletal Physiological Phenomena; Nitriles; Pharmacogenetics; Phenotype; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2013 |
Targeting receptor tyrosine kinases in HER2-negative breast cancer.
Topics: Anastrozole; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Clinical Trials, Phase II as Topic; Disease-Free Survival; Drug Administration Schedule; ErbB Receptors; Female; Gefitinib; Gene Expression Regulation, Neoplastic; Humans; Molecular Targeted Therapy; Nitriles; Prospective Studies; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; Treatment Outcome; Triazoles; Up-Regulation | 2013 |
Co-targeting estrogen receptor and HER2 pathways in breast cancer.
Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Everolimus; Female; Fulvestrant; Gefitinib; Humans; Lapatinib; Letrozole; Molecular Targeted Therapy; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Signal Transduction; Sirolimus; Tamoxifen; Trastuzumab; Triazoles | 2014 |
Aromatase inhibitors for subfertile women with polycystic ovary syndrome.
Topics: Anastrozole; Aromatase Inhibitors; Birth Rate; Clomiphene; Coitus; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Ovary; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Outcome; Randomized Controlled Trials as Topic; Triazoles | 2014 |
Cutaneous adverse effects of hormonal adjuvant therapy for breast cancer: a case of localised urticarial vasculitis following anastrozole therapy and a review of the literature.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Lobular; Chemotherapy, Adjuvant; Drug Eruptions; Female; Humans; Nitriles; Triazoles; Urticaria; Vasculitis | 2014 |
Current concepts in breast cancer chemoprevention.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Estrogen Antagonists; Estrogens; Female; Humans; Incidence; Nitriles; Postmenopause; Premenopause; Prospective Studies; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2014 |
Fulvestrant 250 mg versus anastrozole 1 mg in the treatment of advanced breast cancer: a meta-analysis of randomized controlled trials.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Triazoles; Women | 2014 |
[A case of local recurrence developing thirty-nine years after mastectomy for breast cancer].
Topics: Adenocarcinoma; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy, Needle; Breast Neoplasms; Female; Humans; Mastectomy; Neoplasm Recurrence, Local; Nitriles; Time Factors; Triazoles | 2014 |
Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: American Society of Clinical Oncology clinical practice guideline.
Topics: Ado-Trastuzumab Emtansine; Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Comorbidity; Docetaxel; Drug Administration Schedule; Evidence-Based Medicine; Female; Health Status Disparities; Healthcare Disparities; Humans; Lapatinib; Letrozole; Maytansine; Molecular Targeted Therapy; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Societies, Medical; Taxoids; Trastuzumab; Treatment Outcome; Triazoles; United States | 2014 |
Predictive and prognostic value of the 21-gene recurrence score in hormone receptor-positive, node-positive breast cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease-Free Survival; Female; Genetic Markers; Humans; Nitriles; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Reproducibility of Results; Tamoxifen; Treatment Outcome; Triazoles; Validation Studies as Topic | 2014 |
Aromatase inhibitors in breast cancer prevention.
Topics: Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Neoplasm Invasiveness; Nitriles; Postmenopause; Risk; Triazoles | 2014 |
Is there a role for estrogen activity assays? Recombinant cell bioassay for estrogen: Development and applications.
Topics: Anastrozole; Aromatase Inhibitors; Biological Assay; Breast Neoplasms; Child; Estradiol; Female; Humans; Leuprolide; Male; Nitriles; Puberty, Precocious; Radioimmunoassay; Recombinant Proteins; Reference Values; Saccharomyces cerevisiae; Sensitivity and Specificity; Triazoles; Turner Syndrome | 2015 |
The influence of genetic polymorphisms on the efficacy and side effects of anastrozole in postmenopausal breast cancer patients.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase; Breast Neoplasms; Cytochrome P-450 CYP3A; Female; Glucuronosyltransferase; Humans; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Precision Medicine; Triazoles | 2014 |
Current status of hormone therapy in patients with hormone receptor positive (HR+) advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Neoplasm Metastasis; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2014 |
A new era of improving progression-free survival with dual blockade in postmenopausal HR(+), HER2(-) advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bevacizumab; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Estradiol; Everolimus; Female; Fulvestrant; Humans; Molecular Targeted Therapy; Nitriles; Patient Selection; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Sirolimus; Treatment Failure; Treatment Outcome; Triazoles | 2015 |
Targeting HER2 for the treatment of breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Female; Humans; Lapatinib; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Trastuzumab; Triazoles | 2015 |
Testosterone and breast cancer prevention.
Topics: Anastrozole; Androgens; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Drug Implants; Estrogens; Female; Humans; Nitriles; Testosterone; Triazoles | 2015 |
Ductal Carcinoma In Situ: Treatment Update and Current Trends.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Combined Modality Therapy; Female; Humans; Mammography; Mastectomy, Segmental; Neoplasm Recurrence, Local; Nitriles; Practice Guidelines as Topic; Precision Medicine; Prognosis; Radiotherapy, Adjuvant; Tamoxifen; Triazoles | 2015 |
Effectiveness of aromatase inhibitors in the treatment of advanced endometrial adenocarcinoma.
Topics: Adenocarcinoma; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Treatment Outcome; Triazoles | 2016 |
[Hormonotherapy for breast cancer prevention: What about women with genetic predisposition to breast cancer?].
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Endometrial Neoplasms; Female; Genes, BRCA1; Genes, BRCA2; Genetic Predisposition to Disease; Humans; Mastectomy; Mutation; Nitriles; Prophylactic Surgical Procedures; Raloxifene Hydrochloride; Tamoxifen; Triazoles | 2016 |
Network Meta-Analysis Comparing Overall Survival for Fulvestrant 500 mg Versus Alternative Therapies for Treatment of Postmenopausal, Estrogen Receptor-Positive Advanced Breast Cancer Following Failure on Prior Endocrine Therapy.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Network Meta-Analysis; Nitriles; Postmenopause; Receptors, Estrogen; Treatment Outcome; Triazoles | 2016 |
Unravelling exemestane: From biology to clinical prospects.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Apoptosis; Aromatase Inhibitors; Autophagy; Biotransformation; Breast Neoplasms; Cell Cycle Checkpoints; Cell Line, Tumor; Clinical Trials as Topic; Drug Resistance, Neoplasm; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2016 |
Endocrine therapy for hormone treatment-naïve advanced breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Pyridines; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2016 |
Mechanism of drug resistance in relation to site of metastasis: Meta-analyses of randomized controlled trials in advanced breast cancer according to anticancer strategy.
Topics: Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Disease-Free Survival; Drug Resistance, Neoplasm; Estradiol; Everolimus; Female; Fulvestrant; Humans; Letrozole; Nitriles; Piperazines; Pyridines; Randomized Controlled Trials as Topic; Trastuzumab; Triazoles | 2016 |
Fulvestrant for hormone-sensitive metastatic breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 2017 |
Extended Adjuvant Endocrine Therapy in Breast Cancer: Evidence and Update - A Review.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Drug Administration Schedule; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Triazoles | 2017 |
ADJUVANT (HORMONAL) THERAPY AS A CAUSE OF BONE LOSS IN PATIENTS WITH BREAST CANCER (REVIEW OF LITERATURE).
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Letrozole; Nitriles; Osteoporosis; Postmenopause; Premenopause; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2017 |
A meta-analysis of randomized controlled trials comparing the efficacy and safety of anastrozole versus tamoxifen for breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Randomized Controlled Trials as Topic; Recurrence; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2017 |
HER2 status predicts for upfront AI benefit: A TRANS-AIOG meta-analysis of 12,129 patients from ATAC, BIG 1-98 and TEAM with centrally determined HER2.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Drug Substitution; Female; Humans; Mastectomy; Middle Aged; Multicenter Studies as Topic; Nitriles; Prospective Studies; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome; Triazoles | 2017 |
Use of anastrozole in the chemoprevention and treatment of breast cancer: A literature review.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Postmenopause; Reproducibility of Results; Tamoxifen; Treatment Outcome; Triazoles | 2017 |
Efficacy and safety of endocrine monotherapy as first-line treatment for hormone-sensitive advanced breast cancer: A network meta-analysis.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Letrozole; Neoplasms, Hormone-Dependent; Network Meta-Analysis; Nitriles; Receptor, ErbB-2; Tamoxifen; Triazoles | 2017 |
Personalized prevention in high risk individuals: Managing hormones and beyond.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemoprevention; Early Detection of Cancer; Female; Genes, BRCA1; Genes, BRCA2; Humans; Mammography; Middle Aged; Nitriles; Precision Medicine; Raloxifene Hydrochloride; Risk Assessment; Risk Factors; Tamoxifen; Triazoles | 2018 |
Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome.
Topics: Abortion, Spontaneous; Anastrozole; Aromatase Inhibitors; Birth Rate; Clomiphene; Coitus; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Live Birth; Nitriles; Ovarian Hyperstimulation Syndrome; Ovary; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Outcome; Pregnancy, Multiple; Randomized Controlled Trials as Topic; Triazoles | 2018 |
302 trial(s) available for anastrozole and triazoles
| Article | Year |
|---|---|
ARIMIDEX: a new oral, once-a-day aromatase inhibitor.
Topics: Administration, Oral; Aldosterone; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estradiol; Female; Humans; Hydrocortisone; Nitriles; Triazoles | 1995 |
Arimidex (ZD1033): a selective, potent inhibitor of aromatase in postmenopausal female volunteers.
Topics: Adrenocorticotropic Hormone; Anastrozole; Aromatase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrone; Female; Follicle Stimulating Hormone; Hormones; Humans; Hydrocortisone; Luteinizing Hormone; Nitriles; Postmenopause; Steroids; Triazoles | 1996 |
Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: results of overview analysis of two phase III trials. Arimidex Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Female; Humans; Megestrol; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Prognosis; Survival Rate; Tamoxifen; Triazoles | 1996 |
A randomised trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Megestrol; Middle Aged; Nitriles; Postmenopause; Prospective Studies; Quality of Life; Remission Induction; Survival Rate; Triazoles | 1996 |
Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatisation and plasma oestrogen levels in postmenopausal women with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 1996 |
A phase III trial comparing anastrozole (1 and 10 milligrams), a potent and selective aromatase inhibitor, with megestrol acetate in postmenopausal women with advanced breast carcinoma. Arimidex Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Pregnanes; Triazoles | 1997 |
Validated assay for the quantification of anastrozole in human plasma by capillary gas chromatography-63Ni electron capture detection.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Chromatography, Gas; Drug Stability; Female; Humans; Nitriles; Reproducibility of Results; Sensitivity and Specificity; Triazoles | 1997 |
A randomised comparison of oestrogen suppression with anastrozole and formestane in postmenopausal patients with advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Female; Humans; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 1997 |
Anastrozole versus megestrol acetate in the treatment of postmenopausal women with advanced breast carcinoma: results of a survival update based on a combined analysis of data from two mature phase III trials. Arimidex Study Group.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Megestrol; Nitriles; Postmenopause; Proportional Hazards Models; Survival Rate; Triazoles | 1998 |
The effect of anastrozole on the pharmacokinetics of tamoxifen in post-menopausal women with early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Estrogens; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 1999 |
Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy.
Topics: Anastrozole; Androstenedione; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Female; Humans; Nitriles; Postmenopause; Prospective Studies; Receptors, Estrogen; Treatment Outcome; Triazoles | 1999 |
A randomized, open, parallel-group trial to compare the endocrine effects of oral anastrozole (Arimidex) with intramuscular formestane in postmenopausal women with advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents; Breast Neoplasms; Estrogens; Female; Humans; Injections, Intramuscular; Middle Aged; Nitriles; Triazoles | 1999 |
Critique of survival update analysis from two phase III anastrozole clinical trials.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Survival Rate; Triazoles | 1999 |
Static disease on anastrozole provides similar benefit as objective response in patients with advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Europe; Female; Humans; Megestrol Acetate; Nitriles; Postmenopause; Prospective Studies; Survival Analysis; Triazoles; United States | 1999 |
The effects of neoadjuvant anastrozole (Arimidex) on tumor volume in postmenopausal women with breast cancer: a randomized, double-blind, single-center study.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lymphatic Metastasis; Mammography; Middle Aged; Neoadjuvant Therapy; Nitriles; Postmenopause; Receptors, Estrogen; Treatment Outcome; Triazoles; Ultrasonography | 2000 |
Estrogen suppression in males: metabolic effects.
Topics: Adolescent; Adult; Anastrozole; Antineoplastic Agents, Hormonal; Body Composition; Bone and Bones; Calcium; Estradiol; Estrogen Antagonists; Growth Substances; Hormones; Human Growth Hormone; Humans; Keto Acids; Kinetics; Leuprolide; Male; Muscle, Skeletal; Nitriles; Proteins; Triazoles | 2000 |
A phase II trial of anastrozole in advanced recurrent or persistent endometrial carcinoma: a Gynecologic Oncology Group study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Carcinoma; Drug Administration Schedule; Endometrial Neoplasms; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Triazoles | 2000 |
Aromatase inhibition in the human male reveals a hypothalamic site of estrogen feedback.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Dipeptides; Enzyme Inhibitors; Estradiol; Estrogens; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Hypothalamus; Luteinizing Hormone; Male; Middle Aged; Nitriles; Testosterone; Triazoles | 2000 |
Randomised study of anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2000 |
Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer in 668 postmenopausal women: results of the Tamoxifen or Arimidex Randomized Group Efficacy and Tolerability study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2000 |
Anastrozole is superior to tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: results of a North American multicenter randomized trial. Arimidex Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2000 |
Influence of neoadjuvant anastrozole (Arimidex) on intratumoral estrogen levels and proliferation markers in patients with locally advanced breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Apoptosis; Breast Neoplasms; Estrogens; Female; Hormones; Humans; Ki-67 Antigen; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Proteins; Receptors, Growth Factor; Trefoil Factor-1; Triazoles; Tumor Suppressor Proteins | 2001 |
Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men.
Topics: Administration, Cutaneous; Adult; Anastrozole; Aromatase Inhibitors; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Estradiol; Feedback; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Ketoconazole; Luteinizing Hormone; Male; Nitriles; Prospective Studies; Testosterone; Triazoles | 2001 |
[Aromatase inhibitors: anastrozole versus tamoxifen as first-ine therapy for advanced postmenopausal breast cancer].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers.
Topics: Adult; Anastrozole; Anticoagulants; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Humans; Male; Middle Aged; Nitriles; Triazoles; Warfarin | 2001 |
Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Middle Aged; Nitriles; Postmenopause; Safety; Tamoxifen; Treatment Outcome; Triazoles | 2001 |
Use of the aromatase inhibitor anastrozole in the treatment of patients with advanced prostate carcinoma.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Humans; Male; Middle Aged; Nitriles; Pain Measurement; Prostate-Specific Antigen; Prostatic Neoplasms; Triazoles | 2001 |
Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor positive advanced breast carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Female; Hemorrhage; Humans; Middle Aged; Nitriles; Postmenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Tamoxifen; Thromboembolism; Treatment Outcome; Triazoles | 2001 |
Pharmacokinetics of anastrozole in Chinese male volunteers.
Topics: Adult; Anastrozole; Area Under Curve; Biological Availability; Cross-Over Studies; Humans; Male; Nitriles; Tissue Distribution; Triazoles | 2001 |
Influence of letrozole and anastrozole on total body aromatization and plasma estrogen levels in postmenopausal breast cancer patients evaluated in a randomized, cross-over study.
Topics: Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Cross-Over Studies; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2002 |
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trial.
Topics: Aged; Anastrozole; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Endpoint Determination; Enzyme Inhibitors; Female; Humans; Middle Aged; Nitriles; Postmenopause; Prognosis; Tamoxifen; Triazoles | 2002 |
Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; North America; Postmenopause; Quality of Life; Survival Rate; Triazoles | 2002 |
Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Logistic Models; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Quality of Life; Survival Rate; Triazoles | 2002 |
Effect of neoadjuvant treatment with anastrozole on tumour histology in postmenopausal women with large operable breast cancer.
Topics: Aged; Anastrozole; Antigens, Nuclear; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Middle Aged; Neoadjuvant Therapy; Nitriles; Nuclear Proteins; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2002 |
The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal patients: factors influencing the success of patient recruitment.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Nitriles; Patient Selection; Postmenopause; Surveys and Questionnaires; Tamoxifen; Triazoles | 2002 |
Fulvestrant versus anastrozole as second-line treatment of advanced breast cancer in postmenopausal women.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Dose-Response Relationship, Drug; Estradiol; Female; Follow-Up Studies; Fulvestrant; Humans; Nitriles; Postmenopause; Retrospective Studies; Treatment Outcome; Triazoles | 2002 |
Anastrozole ('Arimidex') blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer.
Topics: Aged; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Estrone; Female; Humans; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Radioimmunoassay; Receptors, Estrogen; Triazoles | 2002 |
Differential effects of androgens and estrogens on bone turnover in normal men.
Topics: Administration, Cutaneous; Adult; Anastrozole; Androgens; Aromatase Inhibitors; Biomarkers; Bone Remodeling; Bone Resorption; Drug Synergism; Enzyme Inhibitors; Estrogens; Gonadotropin-Releasing Hormone; Goserelin; Hormones; Humans; Injections, Subcutaneous; Male; Nitriles; Osteogenesis; Testosterone; Triazoles | 2003 |
Anastrozole as adjuvant therapy for early-stage breast cancer: implications of the ATAC trial.
Topics: Age Factors; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Humans; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Tamoxifen; Time Factors; Treatment Outcome; Triazoles; United States | 2003 |
Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of advanced breast cancer in subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Liver Neoplasms; Lung Neoplasms; Nitriles; Postmenopause; Retrospective Studies; Treatment Outcome; Triazoles | 2003 |
Anastrozole versus tamoxifen as first-line therapy in postmenopausal patients with hormone-dependent advanced breast cancer: a prospective, randomized, phase III study.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Remission Induction; Survival Analysis; Tamoxifen; Triazoles | 2003 |
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Double-Blind Method; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Female; Follow-Up Studies; Fulvestrant; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Salvage Therapy; Treatment Outcome; Triazoles | 2003 |
Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women: a prospective combined analysis of two multicenter trials.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Double-Blind Method; Estradiol; Estrogen Antagonists; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Postmenopause; Prospective Studies; Treatment Outcome; Triazoles | 2003 |
Anastrozole (Arimidex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Female; Follow-Up Studies; Humans; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
Aromatase inhibition for the treatment of idiopathic hypogonadotropic hypogonadism in men with premature ejaculation.
Topics: Adult; Anastrozole; Aromatase; Aromatase Inhibitors; Body Mass Index; Ejaculation; Enzyme Inhibitors; Estradiol; Follow-Up Studies; Gonadal Steroid Hormones; Gonadotropins; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Nitriles; Outcome Assessment, Health Care; Testosterone; Time Factors; Triazoles | 2003 |
Is there a benefit by the sequence anastrozole-formestane for postmenopausal metastatic breast cancer women?
Topics: Adult; Aged; Anastrozole; Androstenedione; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Anastrozole and quinapril can be safely coadministered to elderly women with breast cancer and hypertension: a pharmacokinetic study.
Topics: Age Factors; Aged; Aged, 80 and over; Anastrozole; Antihypertensive Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Interactions; Female; Humans; Hypertension; Nitriles; Quinapril; Tetrahydroisoquinolines; Triazoles | 2003 |
An open randomised trial of second-line endocrine therapy in advanced breast cancer. comparison of the aromatase inhibitors letrozole and anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Triazoles | 2003 |
Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update ana
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
Endogenous estrogens influence endothelial function in young men.
Topics: Adolescent; Adult; Anastrozole; Aorta; Aromatase Inhibitors; Blood Flow Velocity; Blood Pressure; Brachial Artery; C-Reactive Protein; Carotid Arteries; Compliance; Double-Blind Method; Enzyme Inhibitors; Estrogens; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Homocysteine; Humans; Lipoproteins; Male; Nitriles; Nitroglycerin; Prospective Studies; Reference Values; Risk Factors; Triazoles; Ultrasonography; Vasodilation | 2003 |
Advanced breast cancer updates on anastrozole versus tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
'Arimidex' (anastrozole) versus tamoxifen as adjuvant therapy in postmenopausal women with early breast cancer--efficacy overview.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2003 |
The ATAC adjuvant breast cancer trial in postmenopausal women: baseline endometrial subprotocol data.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Protocols; Double-Blind Method; Female; Humans; Hysteroscopy; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2003 |
Phase II trial of anastrozole in women with asymptomatic müllerian cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Fallopian Tube Neoplasms; Female; Humans; Middle Aged; Mixed Tumor, Mullerian; Nitriles; Ovarian Neoplasms; Peritoneal Neoplasms; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2003 |
The effects of post-surgical administration of goserelin plus anastrozole compared to goserelin alone in patients with severe endometriosis: a prospective randomized trial.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Bone Density; Drug Administration Schedule; Drug Therapy, Combination; Endometriosis; Enzyme Inhibitors; Estradiol; Female; Goserelin; Humans; Menopause; Nitriles; Palliative Care; Patient Selection; Postoperative Care; Quality of Life; Secondary Prevention; Severity of Illness Index; Survival Analysis; Treatment Outcome; Triazoles | 2004 |
Does hormone therapy for the treatment of breast cancer have a detrimental effect on memory and cognition? A pilot study.
Topics: Affect; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Breast Neoplasms; Cognition Disorders; Depression; England; Estrogens; Female; Humans; Memory Disorders; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Nitriles; Personality Inventory; Pilot Projects; Reaction Time; Self-Assessment; Tamoxifen; Triazoles; Verbal Learning | 2004 |
Clinical and endocrine data for goserelin plus anastrozole as second-line endocrine therapy for premenopausal advanced breast cancer.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease Progression; Disease-Free Survival; Estradiol; Female; Goserelin; Humans; Injections, Subcutaneous; Middle Aged; Nitriles; Premenopause; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Effects of aromatase inhibition in elderly men with low or borderline-low serum testosterone levels.
Topics: Aged; Aging; Anastrozole; Aromatase Inhibitors; Enzyme Inhibitors; Estrogens; Humans; Hypogonadism; Male; Middle Aged; Nitriles; Quality of Life; Testosterone; Treatment Outcome; Triazoles | 2004 |
Anastrozole ('Arimidex') versus tamoxifen as first-line therapy in postmenopausal women with advanced breast cancer: results of the double-blind cross-over SAKK trial 21/95--a sub-study of the TARGET (Tamoxifen or 'Arimidex' Randomized Group Efficacy and
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Over Studies; Disease-Free Survival; Double-Blind Method; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Survival Rate; Switzerland; Tamoxifen; Triazoles | 2004 |
Treatment of pubertal gynecomastia with the specific aromatase inhibitor anastrozole.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Dehydroepiandrosterone Sulfate; Estrogens; Gynecomastia; Humans; Male; Nitriles; Pilot Projects; Puberty; Treatment Outcome; Triazoles | 2004 |
Breast surgery in the 'Arimidex, Tamoxifen Alone or in Combination' (ATAC) trial: American women are more likely than women from the United Kingdom to undergo mastectomy.
Topics: Age Factors; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Breast Neoplasms; Chemotherapy, Adjuvant; Decision Making; Female; Humans; Mastectomy; Middle Aged; Neoplasm Staging; Nitriles; Odds Ratio; Postmenopause; Risk Factors; Tamoxifen; Triazoles; United Kingdom; United States | 2004 |
Safety and efficacy of anastrozole for the treatment of pubertal gynecomastia: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Anastrozole; Child; Double-Blind Method; Enzyme Inhibitors; Estradiol; Gynecomastia; Humans; Male; Nitriles; Testosterone; Triazoles | 2004 |
The role of aromatase inhibitors in the adjuvant treatment of breast carcinoma: the M. D. Anderson Cancer Center evidence-based approach.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Enzyme Inhibitors; Evidence-Based Medicine; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Triazoles | 2004 |
Giving patients a choice improves quality of life: a multi-centre, investigator-blind, randomised, crossover study comparing letrozole with anastrozole.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Decision Making; Female; Humans; Letrozole; Middle Aged; Nitriles; Patient Participation; Postmenopause; Quality of Life; Single-Blind Method; Treatment Outcome; Triazoles | 2004 |
Acute effects of tamoxifen and third-generation aromatase inhibitors on menopausal symptoms of breast cancer patients.
Topics: Anastrozole; Aromatase Inhibitors; Belgium; Body Mass Index; Breast Neoplasms; Data Interpretation, Statistical; Demography; Dyspareunia; Female; Hot Flashes; Humans; Letrozole; Logistic Models; Memory Disorders; Menopause; Middle Aged; Musculoskeletal Diseases; Nitriles; Pain; Patient Selection; Prospective Studies; Randomized Controlled Trials as Topic; Surveys and Questionnaires; Tamoxifen; Time Factors; Triazoles; Urination Disorders; Vaginal Diseases; Withholding Treatment | 2004 |
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: baseline endometrial sub-protocol data on the effectiveness of transvaginal ultrasonography and diagnostic hysteroscopy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Protocols; Double-Blind Method; Endometrium; Female; Humans; Hysteroscopy; Nitriles; Sensitivity and Specificity; Tamoxifen; Triazoles; Ultrasonography | 2005 |
Anastrozole demonstrates clinical and biological effectiveness in oestrogen receptor-positive breast cancers, irrespective of the erbB2 status.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Proliferation; Double-Blind Method; Female; Genes, erbB-2; Humans; Lymphatic Metastasis; Nitriles; Postmenopause; Receptor, ErbB-2; Receptors, Progesterone; Triazoles | 2004 |
A phase I study of the pharmacokinetics, pharmacodynamics, and safety of single- and multiple-dose anastrozole in healthy, premenopausal female volunteers.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Endometrium; Estradiol; Estrogen Antagonists; Female; Follicle Stimulating Hormone; Gastrointestinal Diseases; Headache; Humans; Menstruation Disturbances; Nitriles; Ovarian Follicle; Premenopause; Reference Values; Time Factors; Triazoles; Ultrasonography | 2004 |
Molecular markers in the endometrium at baseline of postmenopausal patients with early breast cancer in the ATAC (Arimidex, tamoxifen, alone, or in combination) trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Biopsy, Needle; Breast Neoplasms; Combined Modality Therapy; Endometrium; Female; Humans; Immunohistochemistry; Mastectomy; Middle Aged; Nitriles; Postmenopause; Prognosis; Proto-Oncogene Proteins c-bcl-2; Receptors, Estrogen; Receptors, Progesterone; Risk Assessment; Sensitivity and Specificity; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Biomarker investigations from the ATAC trial: the role of TA01.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Humans; Neoplasm Recurrence, Local; Nitriles; Oligonucleotide Array Sequence Analysis; Patient Care Planning; Prognosis; Tamoxifen; Triazoles | 2004 |
Aromatase inhibitor anastrozole for treating endometrial hyperplasia in obese postmenopausal women.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Body Mass Index; Endometrial Hyperplasia; Endometrium; Female; Humans; Middle Aged; Nitriles; Obesity; Postmenopause; Triazoles; Ultrasonography | 2005 |
The role of aromatization in testosterone supplementation: effects on cognition in older men.
Topics: Aged; Aged, 80 and over; Aging; Anastrozole; Aromatase; Aromatase Inhibitors; Double-Blind Method; Estradiol; Humans; Male; Memory; Memory Disorders; Middle Aged; Neuropsychological Tests; Nitriles; Prostate-Specific Antigen; Spatial Behavior; Testosterone; Triazoles; Verbal Learning | 2005 |
Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly men with low testosterone levels.
Topics: Aged; Analysis of Variance; Anastrozole; Aromatase Inhibitors; Biomarkers; C-Reactive Protein; Cardiovascular Diseases; Chi-Square Distribution; Homeostasis; Humans; Hypogonadism; Intercellular Adhesion Molecule-1; Interleukin-6; Lipids; Male; Middle Aged; Nitriles; Risk Factors; Testosterone; Triazoles; Vascular Cell Adhesion Molecule-1 | 2005 |
Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Anilides; Breast Diseases; Double-Blind Method; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Prostate-Specific Antigen; Prostatic Neoplasms; Quality of Life; Tamoxifen; Testosterone; Tosyl Compounds; Triazoles | 2005 |
Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole.
Topics: Aged; Aged, 80 and over; Anastrozole; Anilides; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Diseases; Double-Blind Method; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Placebos; Prostatic Neoplasms; Tamoxifen; Testosterone; Tosyl Compounds; Treatment Outcome; Triazoles | 2005 |
Short-term changes in Ki-67 during neoadjuvant treatment of primary breast cancer with anastrozole or tamoxifen alone or combined correlate with recurrence-free survival.
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Follow-Up Studies; Humans; Ki-67 Antigen; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: influence of hormonal status and HER-2 in breast cancer--a study from the IMPACT trialists.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Double-Blind Method; Female; Humans; Ki-67 Antigen; Middle Aged; Neoadjuvant Therapy; Nitriles; Postmenopause; Predictive Value of Tests; Receptor, ErbB-2; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Effect of anastrozole and tamoxifen on lipid metabolism in Japanese postmenopausal women with early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estradiol; Female; Humans; Japan; Lipids; Lipoprotein Lipase; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
[Survival of breast cancer patients treated with inhibitors of the aromatase vs tamoxifen].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Nitriles; Prospective Studies; Survival Rate; Tamoxifen; Triazoles | 2004 |
Zoledronic acid prevents cancer treatment-induced bone loss.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Resorption; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Female; Goserelin; Humans; Imidazoles; Nitriles; Premenopause; Tamoxifen; Triazoles; Zoledronic Acid | 2005 |
Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Interactions; Gynecomastia; Humans; Male; Middle Aged; Nitriles; Pain; Prostatic Neoplasms; Tamoxifen; Tosyl Compounds; Triazoles | 2005 |
Phase II study of sequential hormonal therapy with anastrozole/exemestane in advanced and metastatic breast cancer.
Topics: Administration, Oral; Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2005 |
Effect of aromatase inhibition on bone metabolism in elderly hypogonadal men.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Resorption; Estradiol; Glycoproteins; Humans; Hypogonadism; Male; Nitriles; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Testosterone; Triazoles | 2005 |
Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; England; ErbB Receptors; Female; Gefitinib; Humans; Ki-67 Antigen; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Protein Kinase Inhibitors; Quinazolines; Receptors, Estrogen; Treatment Outcome; Triazoles; Ultrasonography | 2005 |
Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Nitriles; Postmenopause; Survival Analysis; Survival Rate; Triazoles | 2005 |
Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Female; Humans; Middle Aged; Neoadjuvant Therapy; Nitriles; Odds Ratio; Placebos; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: preliminary results of the Italian Tamoxifen Anastrozole Trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Nitriles; Postmenopause; Prospective Studies; Survival Analysis; Tamoxifen; Triazoles | 2005 |
Comparative effects of anastrozole, tamoxifen alone and in combination on plasma lipids and bone-derived resorption during neoadjuvant therapy in the impact trial.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers; Bone Resorption; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Humans; Lipids; Middle Aged; Neoadjuvant Therapy; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
Anastrazole and oral contraceptives: a novel treatment for endometriosis.
Topics: Adult; Anastrozole; Contraceptives, Oral; Drug Therapy, Combination; Endometriosis; Female; Humans; Middle Aged; Nitriles; Pain Measurement; Pelvic Pain; Prospective Studies; Triazoles | 2005 |
Do biomarker changes during neoadjuvant endocrine therapy reflect breast tumor receptor status?
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Ki-67 Antigen; Mastectomy, Segmental; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Receptor, ErbB-2; Reference Values; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2005 |
The ATAC ('Arimidex', Tamoxifen, Alone or in Combination) adjuvant breast cancer trial: first results of the endometrial sub-protocol following 2 years of treatment.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrial Neoplasms; Endometrium; Female; Humans; Middle Aged; Nitriles; Polyps; Risk Factors; Tamoxifen; Triazoles | 2006 |
Retrospective analysis of time to recurrence in the ATAC trial according to hormone receptor status: an hypothesis-generating study.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2005 |
Proliferation and apoptosis as markers of benefit in neoadjuvant endocrine therapy of breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Female; Humans; In Situ Nick-End Labeling; Ki-67 Antigen; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Prognosis; Tamoxifen; Triazoles | 2006 |
Anastrozole as an adjuvant endocrine treatment for postmenopausal patients with breast cancer: emerging data.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2006 |
Anastrozole versus tamoxifen treatment in postmenopausal women with endocrine-responsive breast cancer and tamoxifen-induced endometrial pathology.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Dilatation and Curettage; Endometrium; Female; Humans; Hysteroscopy; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles; Ultrasonography; Uterine Hemorrhage | 2006 |
The effects of the aromatase inhibitor anastrozole on bone metabolism and cardiovascular risk indices in ovariectomized, androgen-treated female-to-male transsexuals.
Topics: Anastrozole; Androgens; Aromatase Inhibitors; Bone and Bones; C-Reactive Protein; Cardiovascular Diseases; Double-Blind Method; Estradiol; Follicle Stimulating Hormone; Humans; Lipids; Luteinizing Hormone; Nitriles; Ovariectomy; Placebos; Risk Factors; Transsexualism; Triazoles | 2006 |
Comparison of anastrozole versus tamoxifen as preoperative therapy in postmenopausal women with hormone receptor-positive breast cancer: the Pre-Operative "Arimidex" Compared to Tamoxifen (PROACT) trial.
Topics: Aged; Anastrozole; Breast Neoplasms; Confidence Intervals; Cross-Sectional Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Logistic Models; Mastectomy; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Postmenopause; Preoperative Care; Receptors, Estrogen; Reference Values; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
A double-blind randomised trial to evaluate the effect of anastrozole for the treatment of non-toxic multinodular goitre.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Double-Blind Method; Female; Goiter, Nodular; Humans; Middle Aged; Nitriles; Triazoles | 2006 |
Switching to anastrozole versus continued tamoxifen treatment of early breast cancer. Updated results of the Italian tamoxifen anastrozole (ITA) trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Nitriles; Postmenopause; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2006 |
Effect of an aromatase inhibitor on bmd and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial (18233230).
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers; Bone Density; Bone Remodeling; Breast Neoplasms; Female; Fractures, Bone; Hip; Humans; Lumbar Vertebrae; Middle Aged; Nitriles; Postmenopause; Radiography; Risk; Tamoxifen; Triazoles | 2006 |
Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Therapy, Combination; Drug Tolerance; Female; Follow-Up Studies; Humans; Middle Aged; Nitriles; Postmenopause; Risk Assessment; Tamoxifen; Triazoles | 2006 |
Estrogen receptors evolution in neoadjuvant aromatase inhibitor (AI) therapy for breast cancer in elderly women: stability of hormonal receptor expression during treatment.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Neoadjuvant Therapy; Nitriles; Receptors, Estrogen; Triazoles | 2006 |
Quality of life of postmenopausal women in the ATAC ("Arimidex", tamoxifen, alone or in combination) trial after completion of 5 years' adjuvant treatment for early breast cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Follow-Up Studies; Health Status; Humans; Nitriles; Odds Ratio; Patient Dropouts; Postmenopause; Quality of Life; Risk Assessment; Surveys and Questionnaires; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2006 |
A prospective randomized trial comparing anastrozole and clomiphene citrate in an ovulation induction protocol using gonadotropins.
Topics: Administration, Oral; Adult; Anastrozole; Clomiphene; Drug Combinations; Female; Fertility Agents, Female; Gonadotropins; Humans; Infertility, Female; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Outcome; Prospective Studies; Triazoles | 2006 |
Zoledronic acid prevents cancer treatment-induced bone loss in premenopausal women receiving adjuvant endocrine therapy for hormone-responsive breast cancer: a report from the Austrian Breast and Colorectal Cancer Study Group.
Topics: Adult; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Diphosphonates; Female; Goserelin; Humans; Imidazoles; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Tamoxifen; Triazoles; Zoledronic Acid | 2007 |
Relative potencies of anastrozole and letrozole to suppress estradiol in breast cancer patients undergoing ovarian stimulation before in vitro fertilization.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cryopreservation; Estradiol; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Humans; Letrozole; Luteinizing Hormone; Nitriles; Oocytes; Ovulation Induction; Prospective Studies; Triazoles | 2007 |
Lumpectomy plus tamoxifen or anastrozole with or without whole breast irradiation in women with favorable early breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Prospective Studies; Radiotherapy Dosage; Survival Rate; Tamoxifen; Triazoles | 2007 |
The FACE trial: letrozole or anastrozole as initial adjuvant therapy?
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Lymphatic Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Research Design; Triazoles | 2007 |
Favorable outcome in patients with breast cancer in the presence of pathological response after neoadjuvant endocrine therapy.
Topics: Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Disease-Free Survival; Female; Humans; Japan; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Prospective Studies; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Efficacy of letrozole extended adjuvant therapy according to estrogen receptor and progesterone receptor status of the primary tumor: National Cancer Institute of Canada Clinical Trials Group MA.17.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Placebos; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
A randomized comparison of ovulation induction and hormone profile between the aromatase inhibitor anastrozole and clomiphene citrate in women with infertility.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Endometrium; Estradiol; Female; Fertility Agents, Female; Humans; Infertility, Female; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Rate; Triazoles | 2007 |
Phase 2 randomized trial of primary endocrine therapy versus chemotherapy in postmenopausal patients with estrogen receptor-positive breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Female; Humans; Middle Aged; Nitriles; Paclitaxel; Postmenopause; Receptors, Estrogen; Triazoles | 2007 |
Molecular response to aromatase inhibitor treatment in primary breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Female; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Nitriles; Polymerase Chain Reaction; Postmenopause; Receptors, Estrogen; Triazoles; Up-Regulation | 2007 |
Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxifen: the ARNO 95 Study.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Nitriles; Postmenopause; Prospective Studies; Secondary Prevention; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2007 |
Estrogen-dependent increase in bone turnover and bone loss in postmenopausal women with breast cancer treated with anastrozole. Prevention with bisphosphonates.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Breast Neoplasms; Collagen Type I; Diphosphonates; Estradiol; Female; Fractures, Bone; Humans; Middle Aged; Nitriles; Osteocalcin; Osteoporosis, Postmenopausal; Postmenopause; Triazoles | 2007 |
Cost-effectiveness analysis of anastrozole vs tamoxifen in adjuvant therapy for early stage breast cancer in the United Kingdom: the 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen alone or in combination) trial.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles; United Kingdom | 2007 |
A phase II placebo-controlled trial of neoadjuvant anastrozole alone or with gefitinib in early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; ErbB Receptors; Estradiol; Female; Gefitinib; Humans; Ki-67 Antigen; Mastectomy; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Progesterone; Triazoles | 2007 |
RETRACTED: Anastrozole or letrozole for ovulation induction in clomiphene-resistant women with polycystic ovarian syndrome: a prospective randomized trial.
Topics: Abortion, Spontaneous; Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Drug Resistance; Endometrium; Estradiol; Female; Fertility Agents, Female; Humans; Infertility, Female; Letrozole; Nitriles; Ovarian Follicle; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Progesterone; Prospective Studies; Triazoles | 2008 |
Effects of steroidal and nonsteroidal aromatase inhibitors on markers of bone turnover in healthy postmenopausal women.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Lipids; Menopause; Middle Aged; Nitriles; Peptide Fragments; Placebos; Procollagen; Single-Blind Method; Tamoxifen; Triazoles | 2007 |
The effect of anastrazole on symptomatic uterine leiomyomata.
Topics: Adult; Age Factors; Anastrozole; Antineoplastic Agents, Hormonal; Endometrium; Estradiol; Female; Gonadotropins; Hematocrit; Humans; Leiomyomatosis; Middle Aged; Nitriles; Organ Size; Prospective Studies; Severity of Illness Index; Treatment Outcome; Triazoles; Uterine Neoplasms | 2007 |
A decade of letrozole: FACE.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials, Phase III as Topic; Disease-Free Survival; Estrogen Receptor Modulators; Female; Humans; Letrozole; Lymphatic Metastasis; Middle Aged; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles | 2007 |
[Phase II clinical trial of neoadjuvant hormone therapy in comparison with chemotherapy of patients with breast cancer].
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Doxorubicin; Female; Humans; Mammography; Middle Aged; Neoadjuvant Therapy; Nitriles; Paclitaxel; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome; Triazoles | 2007 |
Switching to anastrozole after tamoxifen improves survival in postmenopausal women with breast cancer.
Topics: Aged; Anastrozole; Breast Neoplasms; Female; Humans; Nitriles; Postmenopause; Prospective Studies; Survivors; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
The ATAC trial: the vanguard trial for use of aromatase inhibitors in early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Effects of third generation aromatase inhibitors on bone health and other safety parameters: results of an open, randomised, multi-centre study of letrozole, exemestane and anastrozole in healthy postmenopausal women.
Topics: Adrenal Glands; Alkaline Phosphatase; Anastrozole; Androstadienes; Aromatase Inhibitors; Biomarkers; Body Mass Index; Bone and Bones; Bone Remodeling; Bone Resorption; Female; Humans; Letrozole; Lipids; Middle Aged; Nitriles; Postmenopause; Triazoles | 2007 |
Extended adjuvant therapy with anastrozole among postmenopausal breast cancer patients: results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a.
Topics: Aged; Aged, 80 and over; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Austria; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Logistic Models; Lymphatic Metastasis; Male; Middle Aged; Nitriles; Odds Ratio; Postmenopause; Proportional Hazards Models; Prospective Studies; Receptors, Estrogen; Receptors, Progesterone; Research Design; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Histopathological assessment of anastrozole and tamoxifen as preoperative (neoadjuvant) treatment in postmenopausal Japanese women with hormone receptor-positive breast cancer in the PROACT trial.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Female; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2008 |
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Alkylating; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; Fractures, Bone; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Tamoxifen; Time Factors; Triazoles | 2008 |
Anastrozole increases predicted adult height of short adolescent males treated with growth hormone: a randomized, placebo-controlled, multicenter trial for one to three years.
Topics: Adolescent; Adult; Age Determination by Skeleton; Anastrozole; Aromatase Inhibitors; Blood Glucose; Body Composition; Body Height; Bone Density; Follow-Up Studies; Growth Disorders; Growth Hormone; Humans; Lipids; Male; Nitriles; Puberty; Testosterone; Triazoles | 2008 |
Clomiphene citrate or anastrozole for ovulation induction in women with polycystic ovary syndrome? A prospective controlled trial.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Dose-Response Relationship, Drug; Endometrium; Female; Fertility Agents, Female; Humans; Nitriles; Ovarian Follicle; Ovulation; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Rate; Prospective Studies; Treatment Outcome; Triazoles | 2009 |
ERBB2 status and outcome of endocrine treatment.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; ErbB Receptors; Female; Humans; Nitriles; Postmenopause; Prognosis; Tamoxifen; Triazoles | 2008 |
Relationship between quantitative estrogen and progesterone receptor expression and human epidermal growth factor receptor 2 (HER-2) status with recurrence in the Arimidex, Tamoxifen, Alone or in Combination trial.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Survival Rate; Tamoxifen; Time Factors; Tissue Array Analysis; Treatment Outcome; Triazoles | 2008 |
Action of aromatase inhibitor for treatment of uterine leiomyoma in perimenopausal patients.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Estradiol; Female; Follicle Stimulating Hormone; Humans; Leiomyoma; Menstruation; Middle Aged; Nitriles; Perimenopause; Triazoles; Uterine Neoplasms | 2009 |
Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Female; Humans; Neoplasm Invasiveness; Nitriles; Postmenopause; Prospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Letrozole suppresses plasma estradiol and estrone sulphate more completely than anastrozole in postmenopausal women with breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cross-Over Studies; Estradiol; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Follicular and endocrine response to anastrozole versus clomiphene citrate administered in follicular phase to normoovulatory women: a randomized comparison.
Topics: Adolescent; Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Estradiol; Female; Follicle Stimulating Hormone; Follicular Phase; Humans; Luteinizing Hormone; Nitriles; Ovarian Follicle; Ovulation Induction; Sex Hormone-Binding Globulin; Triazoles | 2009 |
A randomised study of the effects of letrozole and anastrozole on oestrogen receptor positive breast cancers in postmenopausal women.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Progesterone; Treatment Outcome; Triazoles | 2009 |
The effects of neoadjuvant anastrozole and tamoxifen on circulating vascular endothelial growth factor and soluble vascular endothelial growth factor receptor 1 in breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Double-Blind Method; Estrogen Antagonists; Female; Humans; Middle Aged; Neoadjuvant Therapy; Nitriles; Tamoxifen; Triazoles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2008 |
Short-term androgen priming by use of aromatase inhibitor and hCG before controlled ovarian stimulation for IVF. A randomized controlled trial.
Topics: Adult; Anastrozole; Androgens; Aromatase Inhibitors; Chorionic Gonadotropin; Estradiol; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicle Stimulating Hormone, Human; Follicular Fluid; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Rate; Progesterone; Recombinant Proteins; Sperm Injections, Intracytoplasmic; Testosterone; Triazoles | 2008 |
Evaluation of endometrial thickness in hormone receptor positive early stage breast cancer postmenopausal women switching from adjuvant tamoxifen treatment to anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Endometrium; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles; Ultrasonography | 2008 |
Effects of aromatase inhibition in hypogonadal older men: a randomized, double-blind, placebo-controlled trial.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Biological Availability; Body Composition; Dinoprostone; Double-Blind Method; Humans; Hypogonadism; Male; Middle Aged; Nitriles; Outcome Assessment, Health Care; Testosterone; Triazoles | 2009 |
Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Female; Goserelin; Humans; Imidazoles; Linear Models; Nitriles; Osteoporosis; Premenopause; Prospective Studies; Tamoxifen; Triazoles; Zoledronic Acid | 2008 |
Effects of anastrozole on cognitive performance in postmenopausal women: a randomised, double-blind chemoprevention trial (IBIS II).
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Attention; Breast Neoplasms; Cognition; Double-Blind Method; Female; Humans; Memory; Middle Aged; Neuropsychological Tests; Nitriles; Postmenopause; Triazoles | 2008 |
Improving informed consent: pilot of a decision aid for women invited to participate in a breast cancer prevention trial (IBIS-II DCIS).
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Australia; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Decision Support Techniques; Feedback; Female; Health Knowledge, Attitudes, Practice; Humans; Informed Consent; Middle Aged; Nitriles; Patient Education as Topic; Patient Selection; Pilot Projects; Risk Assessment; Selective Estrogen Receptor Modulators; Tamoxifen; Teaching Materials; Triazoles | 2008 |
Estrogen, testosterone, and sequential movement in men.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Anastrozole; Androgens; Aromatase Inhibitors; Estrogens; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Middle Aged; Movement; Nitriles; Radioimmunoassay; Reaction Time; Regression Analysis; Testosterone; Time Factors; Triazoles | 2008 |
Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radioimmunoassay; Triazoles | 2008 |
Prevention of anastrozole-induced bone loss with monthly oral ibandronate during adjuvant aromatase inhibitor therapy for breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Diseases; Breast Neoplasms; Diphosphonates; Double-Blind Method; Female; Fractures, Bone; Humans; Ibandronic Acid; Lumbar Vertebrae; Middle Aged; Nitriles; Placebos; Triazoles | 2008 |
Incidence of joint symptoms and bone fractures in Japanese postmenopausal breast cancer patients treated with adjuvant anastrozole.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Asian People; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fractures, Bone; Humans; Incidence; Japan; Joint Diseases; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles; White People | 2009 |
Pregnancy outcome after ovulation induction with aromatase inhibitors or clomiphene citrate in unexplained infertility.
Topics: Abortion, Spontaneous; Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Female; Fertility Agents, Female; Humans; Infant, Newborn; Infertility, Female; Letrozole; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Outcome; Triazoles | 2009 |
Comparing the cost of adjuvant anastrozole with the benefits of managing less patients with relapsed breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Female; Health Care Costs; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Triazoles; United Kingdom | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Disease-Free Survival; Drug Therapy, Combination; Estrogen Antagonists; Female; Follow-Up Studies; Goserelin; Humans; Imidazoles; Middle Aged; Nitriles; Premenopause; Receptors, Estrogen; Tamoxifen; Triazoles; Zoledronic Acid | 2009 |
Combined down-regulation by aromatase inhibitor and GnRH-agonist in IVF patients with endometriomas-A pilot study.
Topics: Adult; Anastrozole; Aromatase Inhibitors; CA-125 Antigen; Down-Regulation; Drug Therapy, Combination; Endometriosis; Estrogens; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; Goserelin; Humans; Nitriles; Pilot Projects; Pregnancy; Pregnancy Outcome; Prospective Studies; Triazoles; Uterine Diseases | 2009 |
A comparative study of exemestane versus anastrozole in patients with postmenopausal breast cancer with visceral metastases.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Brain Neoplasms; Breast Neoplasms; Female; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Nitriles; Pilot Projects; Postmenopause; Prognosis; Retrospective Studies; Survival Rate; Treatment Outcome; Triazoles | 2009 |
21-Gene expression profile assay on core needle biopsies predicts responses to neoadjuvant endocrine therapy in breast cancer patients.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biopsy, Needle; Breast Neoplasms; Disease-Free Survival; Female; Gene Expression Profiling; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Predictive Value of Tests; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2009 |
Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 2009 |
A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Drug Administration Schedule; Estradiol; Female; Humans; Ki-67 Antigen; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2010 |
Aromatase inhibitor-induced carpal tunnel syndrome: results from the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Middle Aged; Nitriles; Postmenopause; Risk Factors; Tamoxifen; Triazoles | 2009 |
Comparison of the effect of the aromatase inhibitor, anastrazole, to the antioestrogen, tamoxifen citrate, on canine prostate and semen.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Dog Diseases; Dogs; Estrogen Antagonists; Male; Nitriles; Prostate; Prostatic Hyperplasia; Semen; Tamoxifen; Triazoles | 2009 |
[Safety and compliance with UFT (tegafur and uracil) alone and in combination with hormone therapy in patients with breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Patient Compliance; Postmenopause; Tamoxifen; Tegafur; Triazoles; Uracil | 2009 |
Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM study.
Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Confidence Intervals; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Statistics, Nonparametric; Survival Analysis; Trastuzumab; Treatment Outcome; Triazoles | 2009 |
Effects of aromatase inhibition on bone mineral density and bone turnover in older men with low testosterone levels.
Topics: Aged; Aging; Anastrozole; Aromatase Inhibitors; Biomarkers; Bone and Bones; Bone Density; Double-Blind Method; Endpoint Determination; Enzyme-Linked Immunosorbent Assay; Hormones; Humans; Male; Middle Aged; Nitriles; Patient Compliance; Steroids; Testis; Testosterone; Triazoles | 2009 |
Randomized biomarker trial of anastrozole or low-dose tamoxifen or their combination in subjects with breast intraepithelial neoplasia.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast; Breast Neoplasms; Cytochrome P-450 CYP2D6; Disease-Free Survival; Female; Genotype; Humans; Nitriles; Pharmacogenetics; Precancerous Conditions; Risk; Tamoxifen; Treatment Outcome; Triazoles | 2009 |
A study of the effects of the aromatase inhibitors anastrozole and letrozole on bone metabolism in postmenopausal women with estrogen receptor-positive breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Bone and Bones; Bone Resorption; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2010 |
Effect of a switch of aromatase inhibitors on musculoskeletal symptoms in postmenopausal women with hormone-receptor-positive breast cancer: the ATOLL (articular tolerance of letrozole) study.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Musculoskeletal Diseases; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2010 |
Prevention of aromatase inhibitor-induced bone loss using risedronate: the SABRE trial.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Double-Blind Method; Etidronic Acid; Female; Fractures, Bone; Hormone Replacement Therapy; Humans; Middle Aged; Neoplasm Staging; Nitriles; Osteoporosis, Postmenopausal; Postmenopause; Prognosis; Risedronic Acid; Survival Rate; Treatment Outcome; Triazoles | 2010 |
A comparison of anastrozole and testosterone versus placebo and testosterone for treatment of sexual dysfunction in men with epilepsy and hypogonadism.
Topics: Adolescent; Adult; Anastrozole; Aromatase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Humans; Hypogonadism; Injections, Intramuscular; Male; Middle Aged; Nitriles; Prospective Studies; Sexual Dysfunction, Physiological; Testosterone; Triazoles; Young Adult | 2010 |
Prediction of risk of distant recurrence using the 21-gene recurrence score in node-negative and node-positive postmenopausal patients with breast cancer treated with anastrozole or tamoxifen: a TransATAC study.
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Genetic Testing; Humans; Lymph Nodes; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Risk Factors; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2010 |
Phase II, randomized trial to compare anastrozole combined with gefitinib or placebo in postmenopausal women with hormone receptor-positive metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; ErbB Receptors; Female; Gefitinib; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Prospective Studies; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tissue Distribution; Treatment Outcome; Triazoles | 2010 |
Secretagogue type, sex-steroid milieu, and abdominal visceral adiposity individually determine secretagogue-stimulated cortisol secretion.
Topics: Abdominal Fat; Age Factors; Analysis of Variance; Anastrozole; Arginine; Dihydrotestosterone; Double-Blind Method; Estradiol; Growth Hormone-Releasing Hormone; Humans; Hydrocortisone; Male; Nitriles; Oligopeptides; Prospective Studies; Somatostatin; Testosterone; Triazoles | 2010 |
Cost-effectiveness analysis of anastrozole versus tamoxifen in adjuvant therapy for early-stage breast cancer - a health-economic analysis based on the 100-month analysis of the ATAC trial and the German health system.
Topics: Anastrozole; Antineoplastic Agents; Breast Neoplasms; Computer Simulation; Cost-Benefit Analysis; Female; Germany; Health Care Costs; Humans; Incidence; Middle Aged; Models, Economic; Nitriles; Tamoxifen; Triazoles | 2010 |
Phase III randomized adjuvant study of tamoxifen alone versus sequential tamoxifen and anastrozole in Japanese postmenopausal women with hormone-responsive breast cancer: N-SAS BC03 study.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Japan; Kaplan-Meier Estimate; Neoplasm Staging; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2010 |
Management of anastrozole-induced bone loss in breast cancer patients with oral risedronate: results from the ARBI prospective clinical trial.
Topics: Administration, Oral; Aged; Anastrozole; Aromatase Inhibitors; Arthralgia; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Drug Therapy, Combination; Dyspepsia; Etidronic Acid; Female; Humans; Middle Aged; Nausea; Nitriles; Osteoporosis, Postmenopausal; Patient Dropouts; Prospective Studies; Risedronic Acid; Risk Factors; Time Factors; Treatment Outcome; Triazoles | 2010 |
Adding zoledronic acid to endocrine therapy in the adjuvant treatment of hormone-sensitive breast cancer in premenopausal women: a new care standard or a provocative idea?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Drug Therapy, Combination; Female; Humans; Imidazoles; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Prognosis; Survival Rate; Tamoxifen; Triazoles; Zoledronic Acid | 2010 |
Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Double-Blind Method; Estrogen Antagonists; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Triazoles | 2010 |
Phase II trial of anastrozole plus goserelin in the treatment of hormone receptor-positive, metastatic carcinoma of the breast in premenopausal women.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Goserelin; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Triazoles | 2010 |
The ATAC adjuvant breast-cancer trial: six-year results of the endometrial subprotocol.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrium; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2010 |
Anastrozole and letrozole: an investigation and comparison of quality of life and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cross-Over Studies; Endocrine System; Humans; Letrozole; Middle Aged; Nitriles; Quality of Life; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Uterine and quality of life changes in postmenopausal women with an asymptomatic tamoxifen-thickened endometrium randomized to continuation of tamoxifen or switching to anastrozole.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Humans; Middle Aged; Nitriles; Postmenopause; Quality of Life; Sexual Dysfunction, Physiological; Tamoxifen; Treatment Outcome; Triazoles; Uterus | 2011 |
Short-term anastrozole therapy reduces Ki-67 and progesterone receptor expression in invasive breast cancer: a prospective, placebo-controlled, double-blind trial.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Double-Blind Method; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Nitriles; Prospective Studies; Receptors, Progesterone; Tamoxifen; Triazoles | 2011 |
Long-term effects of anastrozole on bone mineral density: 7-year results from the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Density; Bone Resorption; Breast Neoplasms; Female; Hip; Humans; Lumbar Vertebrae; Nitriles; Tamoxifen; Time; Triazoles | 2011 |
Fulvestrant 250 mg versus anastrozole for Chinese patients with advanced breast cancer: results of a multicentre, double-blind, randomised phase III trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; China; Disease Progression; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Time Factors; Treatment Outcome; Triazoles | 2011 |
Phase I/II study of sorafenib with anastrozole in patients with hormone receptor positive aromatase inhibitor resistant metastatic breast cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzenesulfonates; Breast Neoplasms; Disease-Free Survival; Drug Resistance, Neoplasm; Endothelial Cells; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Niacinamide; Nitriles; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Receptors, Estrogen; Receptors, Progesterone; Sorafenib; Stem Cells; Time Factors; Treatment Outcome; Triazoles; United States | 2011 |
Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial.
Topics: Administration, Oral; Anastrozole; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Neoplasm Staging; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2010 |
Bicalutamide plus anastrozole for the treatment of gonadotropin-independent precocious puberty in boys with testotoxicosis: a phase II, open-label pilot study (BATT).
Topics: Anastrozole; Anilides; Bone Development; Child; Child, Preschool; Drug Therapy, Combination; Gonadotropins; Growth; Humans; Male; Nitriles; Pilot Projects; Puberty, Precocious; Tosyl Compounds; Triazoles | 2010 |
Genome-wide case-control study of musculoskeletal adverse events and functional genomics in women receiving aromatase inhibitors: going beyond associations.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Female; Gene Expression; Genome-Wide Association Study; Humans; Interleukin-17; Linkage Disequilibrium; Musculoskeletal Diseases; Nitriles; Pharmacogenetics; Polymorphism, Single Nucleotide; Triazoles | 2010 |
The effect of exemestane, anastrozole, and tamoxifen on lipid profiles in Japanese postmenopausal early breast cancer patients: final results of National Surgical Adjuvant Study BC 04, the TEAM Japan sub-study.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Humans; Japan; Lipids; Middle Aged; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles; Triglycerides | 2011 |
Anastrozole vs. clomiphene citrate in infertile women with ovulatory dysfunction: a phase II, randomized, dose-finding study.
Topics: Adolescent; Adult; Anastrozole; Clomiphene; Dose-Response Relationship, Drug; Double-Blind Method; Female; Fertility Agents, Female; Humans; Infertility, Female; Nitriles; Ovarian Hyperstimulation Syndrome; Ovulation; Ovulation Induction; Pregnancy; Pregnancy Rate; Triazoles; Young Adult | 2011 |
Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose-response study.
Topics: Adolescent; Adult; Anastrozole; Anovulation; Clomiphene; Dose-Response Relationship, Drug; Female; Fertility Agents, Female; Humans; Infertility, Female; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Rate; Single-Blind Method; Triazoles; Young Adult | 2011 |
Health-related quality of life and psychological distress of breast cancer patients after surgery during a phase III randomized trial comparing continuation of tamoxifen with switching to anastrozole after adjuvant tamoxifen for 1-4 years: N-SAS BC 03.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Quality of Life; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Effects of exemestane, anastrozole and tamoxifen on bone mineral density and bone turnover markers in postmenopausal early breast cancer patients: results of N-SAS BC 04, the TEAM Japan substudy.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Bone and Bones; Bone Density; Bone Resorption; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2010 |
Impact of body mass index on the efficacy of endocrine therapy in premenopausal patients with breast cancer: an analysis of the prospective ABCSG-12 trial.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Female; Goserelin; Humans; Middle Aged; Nitriles; Premenopause; Prospective Studies; Recurrence; Retrospective Studies; Risk; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based int
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptors, Estrogen; Triazoles | 2011 |
Effects of toremifene and anastrozole on serum lipids and bone metabolism in postmenopausal females with estrogen receptor-positive breast cancer: the results of a 2-year multicenter open randomized study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Bone and Bones; Breast Neoplasms; Female; Humans; Lipid Metabolism; Lipids; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Toremifene; Triazoles | 2011 |
Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG-12 randomised trial.
Topics: Adult; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Disease-Free Survival; Female; Follow-Up Studies; Humans; Imidazoles; Middle Aged; Neoplasm Staging; Nitriles; Premenopause; Tamoxifen; Treatment Outcome; Triazoles; Zoledronic Acid | 2011 |
Androgens and musculoskeletal symptoms among breast cancer patients on aromatase inhibitor therapy.
Topics: Aged; Anastrozole; Androstadienes; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Female; Humans; Letrozole; Middle Aged; Musculoskeletal Pain; Nitriles; Testosterone; Triazoles | 2011 |
Hormonal therapy plus bevacizumab in postmenopausal patients who have hormone receptor-positive metastatic breast cancer: a phase II Trial of the Sarah Cannon Oncology Research Consortium.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Disease-Free Survival; Estradiol; Female; Fulvestrant; Hormone Replacement Therapy; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2011 |
Vitamin D and aromatase inhibitor-induced musculoskeletal symptoms (AIMSS): a phase II, double-blind, placebo-controlled, randomized trial.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Calcium; Ergocalciferols; Female; Humans; Middle Aged; Musculoskeletal Diseases; Nitriles; Pain; Parathyroid Hormone; Triazoles; Vitamin D | 2011 |
Exemestane versus anastrozole as front-line endocrine therapy in postmenopausal patients with hormone receptor-positive, advanced breast cancer: final results from the Spanish Breast Cancer Group 2001-03 phase 2 randomized trial.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Disease-Free Survival; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2012 |
Differentially expressed genes in window trials are influenced by the wound-healing process: lessons learned from a pilot study with anastrozole.
Topics: Aged; Aged, 80 and over; Anastrozole; Antigens, CD34; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Middle Aged; Nitriles; Oligonucleotide Array Sequence Analysis; Paraffin Embedding; Pilot Projects; Preoperative Period; Triazoles; Wound Healing | 2012 |
A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Cell Cycle; Cyclin D1; Estradiol; Female; Fulvestrant; Gefitinib; Humans; Ki-67 Antigen; Male; Mitogen-Activated Protein Kinases; Neoadjuvant Therapy; Nitriles; Oncogene Protein v-akt; Proto-Oncogene Proteins; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2011 |
Influence of comorbidities and age on risk of death without recurrence: a retrospective analysis of the Arimidex, Tamoxifen Alone or in Combination trial.
Topics: Adult; Age Factors; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Comorbidity; Double-Blind Method; Female; Humans; Middle Aged; Nitriles; Retrospective Studies; Risk; Tamoxifen; Triazoles | 2011 |
Outcomes of Japanese breast cancer patients treated with pre-operative and post-operative anastrozole or tamoxifen.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Asian People; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoadjuvant Therapy; Nitriles; Postoperative Period; Tamoxifen; Triazoles | 2012 |
Using the gene ontology to scan multilevel gene sets for associations in genome wide association studies.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Data Mining; Female; Genome-Wide Association Study; Genome, Human; Humans; Linkage Disequilibrium; Models, Genetic; Nitriles; Polymorphism, Single Nucleotide; Raloxifene Hydrochloride; Software; Tamoxifen; Triazoles | 2012 |
Effect of baseline serum vitamin D levels on aromatase inhibitors induced musculoskeletal symptoms: results from the IBIS-II, chemoprevention study using anastrozole.
Topics: Adult; Aged; Anastrozole; Anticarcinogenic Agents; Aromatase Inhibitors; Arthralgia; Biomarkers; Breast Neoplasms; Double-Blind Method; Female; Humans; Logistic Models; Middle Aged; Nitriles; Odds Ratio; Placebos; Postmenopause; Risk Assessment; Risk Factors; Treatment Outcome; Triazoles; United Kingdom; Vitamin D; Vitamin D Deficiency | 2012 |
Health-related quality of life, psychological distress, and adverse events in postmenopausal women with breast cancer who receive tamoxifen, exemestane, or anastrozole as adjuvant endocrine therapy: National Surgical Adjuvant Study of Breast Cancer 04 (N-
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Depression; Female; Humans; Maintenance Chemotherapy; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Stress, Psychological; Surveys and Questionnaires; Tamoxifen; Treatment Outcome; Triazoles | 2012 |
Neoadjuvant anastrozole versus tamoxifen in patients receiving goserelin for premenopausal breast cancer (STAGE): a double-blind, randomised phase 3 trial.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Goserelin; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Receptor, ErbB-2; Tamoxifen; Triazoles | 2012 |
Acute sex steroid withdrawal increases cholesterol efflux capacity and HDL-associated clusterin in men.
Topics: Adolescent; Adult; Anastrozole; Androgens; Apolipoproteins B; Aromatase Inhibitors; Cholesterol; Cholesterol, HDL; Clusterin; Drug Administration Schedule; Fasting; Gonadotropin-Releasing Hormone; Humans; Lipids; Lipoproteins, HDL; Male; Middle Aged; Nitriles; Oligopeptides; Testosterone; Time Factors; Triazoles; Young Adult | 2012 |
Tamoxifen and anastrozole as a sequencing strategy: a randomized controlled trial in postmenopausal patients with endocrine-responsive early breast cancer from the Austrian Breast and Colorectal Cancer Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Austria; Breast Neoplasms; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Prospective Studies; Survival Rate; Tamoxifen; Triazoles | 2012 |
Pharmacokinetic comparison of 2 formulations of anastrozole (1 mg) in healthy Korean male volunteers: a randomized, single-dose, 2-period, 2-sequence, crossover study.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Chemistry, Pharmaceutical; Cross-Over Studies; Double-Blind Method; Humans; Male; Middle Aged; Nitriles; Triazoles | 2012 |
Aromatase inhibitors and calcium absorption in early stage breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Calcium; Diet; Female; Humans; Intestinal Absorption; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles; Vitamin D | 2012 |
FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Recurrence; Triazoles | 2012 |
A randomized trial of combination anastrozole plus gefitinib and of combination fulvestrant plus gefitinib in the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Fulvestrant; Gefitinib; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Survival Analysis; Treatment Outcome; Triazoles | 2012 |
Effects of cyclin D1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclin D1; Female; Follow-Up Studies; Gene Amplification; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Predictive Value of Tests; Prognosis; Receptors, Estrogen; Tamoxifen; Treatment Outcome; Triazoles | 2012 |
A prospective, multicenter, controlled, observational study to evaluate the efficacy of a patient support program in improving patients' persistence to adjuvant aromatase inhibitor medication for postmenopausal, early stage breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Patient Compliance; Physician-Patient Relations; Postmenopause; Practice Patterns, Physicians'; Prospective Studies; Surveys and Questionnaires; Triazoles | 2012 |
Changes in hormonal profile and seminal parameters with use of aromatase inhibitors in management of infertile men with low testosterone to estradiol ratios.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Estradiol; Hormones; Humans; Infertility, Male; Letrozole; Male; Nitriles; Organ Size; Semen Analysis; Testis; Testosterone; Triazoles | 2012 |
Short-term and low-dose prednisolone administration reduces aromatase inhibitor-induced arthralgia in patients with breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Anti-Inflammatory Agents; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Prednisolone; Triazoles | 2012 |
Lipid profiles within the SABRE trial of anastrozole with and without risedronate.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Breast Neoplasms; Cholesterol, HDL; Cholesterol, LDL; Etidronic Acid; Female; Humans; Lipids; Middle Aged; Nitriles; Risedronic Acid; Treatment Outcome; Triazoles; Triglycerides | 2012 |
Combination anastrozole and fulvestrant in metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Disease-Free Survival; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Metastasis; Nitriles; Postmenopause; Triazoles | 2012 |
Analysis of Ki-67 expression with neoadjuvant anastrozole or tamoxifen in patients receiving goserelin for premenopausal breast cancer.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; Female; Goserelin; Humans; Ki-67 Antigen; Middle Aged; Neoadjuvant Therapy; Nitriles; Predictive Value of Tests; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
Fulvestrant 500 mg versus anastrozole 1 mg for the first-line treatment of advanced breast cancer: follow-up analysis from the randomized 'FIRST' study.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Follow-Up Studies; Fulvestrant; Humans; Neoplasm Staging; Nitriles; Treatment Outcome; Triazoles | 2012 |
Phase II study of neoadjuvant anastrozole and concurrent radiotherapy for postmenopausal breast cancer patients.
Topics: Aged; Aged, 80 and over; Anastrozole; Breast Neoplasms; Chemoradiotherapy; Female; Humans; Middle Aged; Neoadjuvant Therapy; Nitriles; Postmenopause; Prospective Studies; Receptors, Estrogen; Treatment Outcome; Triazoles | 2014 |
Use of a urine anastrozole assay to determine treatment discontinuation among women with hormone-sensitive breast cancer: a pilot study.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Medication Adherence; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Pilot Projects; Postmenopause; Surveys and Questionnaires; Treatment Outcome; Triazoles | 2012 |
Exemestane versus anastrozole in postmenopausal women with early breast cancer: NCIC CTG MA.27--a randomized controlled phase III trial.
Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; History, 18th Century; Hot Flashes; Humans; Hypercholesterolemia; Kaplan-Meier Estimate; Middle Aged; Nitriles; Osteoporosis; Postmenopause; Time Factors; Treatment Outcome; Triazoles | 2013 |
The Patient's Anastrozole Compliance to Therapy (PACT) Program: a randomized, in-practice study on the impact of a standardized information program on persistence and compliance to adjuvant endocrine therapy in postmenopausal women with early breast cance
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Early Detection of Cancer; Female; Follow-Up Studies; Humans; Medication Adherence; Middle Aged; Nitriles; Patient Compliance; Postmenopause; Prospective Studies; Triazoles | 2013 |
Switching to anastrozole versus continued tamoxifen treatment of early breast cancer: long term results of the Italian Tamoxifen Anastrozole trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Endometrial Neoplasms; Female; Follow-Up Studies; Fractures, Bone; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Risk Factors; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2013 |
Influence of compliance on bone mineral density changes in postmenopausal women with early breast cancer on Anastrozole.
Topics: Absorptiometry, Photon; Aged; Anastrozole; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Femur; Humans; Lumbar Vertebrae; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Patient Compliance; Postmenopause; Receptors, Steroid; Time Factors; Treatment Outcome; Triazoles | 2013 |
Efficacy of goserelin plus anastrozole in premenopausal women with advanced or recurrent breast cancer refractory to an LH-RH analogue with tamoxifen: results of the JMTO BC08-01 phase II trial.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; ErbB Receptors; Female; Gonadotropin-Releasing Hormone; Goserelin; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2013 |
A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Estradiol; Female; Follow-Up Studies; Fulvestrant; Humans; Middle Aged; Neoplasm Grading; Nitriles; Postmenopause; Preoperative Care; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2013 |
Predictors of recovery of ovarian function during aromatase inhibitor therapy.
Topics: Adult; Amenorrhea; Anastrozole; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Estradiol; Female; Humans; Middle Aged; Nitriles; Ovary; Primary Ovarian Insufficiency; Prospective Studies; Receptors, Estrogen; Tamoxifen; Triazoles; Uterine Hemorrhage | 2013 |
A randomized, double-blind, controlled study of exemestane versus anastrozole for the first-line treatment of postmenopausal Japanese women with hormone-receptor-positive advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Bone and Bones; Breast Neoplasms; Female; Humans; Japan; Lipids; Middle Aged; Neoplasm Grading; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2013 |
Prevalence of menopausal symptoms and their influence on adherence in women with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Anxiety; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Hot Flashes; Humans; Letrozole; Medication Adherence; Middle Aged; Musculoskeletal Pain; Nitriles; Sleep Wake Disorders; Time Factors; Triazoles; Urinary Bladder Diseases; Vaginal Diseases | 2014 |
The predictive impact of body mass index on the efficacy of extended adjuvant endocrine treatment with anastrozole in postmenopausal patients with breast cancer: an analysis of the randomised ABCSG-6a trial.
Topics: Adolescent; Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Obesity; Overweight; Postmenopause; Retrospective Studies; Triazoles; Young Adult | 2013 |
Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentr
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease Progression; Disease-Free Survival; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Metastasis; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2013 |
Prediction of late distant recurrence in patients with oestrogen-receptor-positive breast cancer: a prospective comparison of the breast-cancer index (BCI) assay, 21-gene recurrence score, and IHC4 in the TransATAC study population.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Follow-Up Studies; Gene Expression Profiling; Humans; Immunoenzyme Techniques; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Prognosis; Prospective Studies; Receptors, Estrogen; Tamoxifen; Triazoles | 2013 |
Estrogen receptor alpha/beta ratio and estrogen receptor beta as predictors of endocrine therapy responsiveness-a randomized neoadjuvant trial comparison between anastrozole and tamoxifen for the treatment of postmenopausal breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
Neoadjuvant treatment of endometrial cancer using anastrozole: a randomised pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Cell Growth Processes; Endometrial Neoplasms; Estrogen Receptor alpha; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Neoadjuvant Therapy; Nitriles; Pilot Projects; Placebos; Proto-Oncogene Proteins c-bcl-2; Receptors, Progesterone; Triazoles | 2013 |
Anastrozole for prevention of breast cancer in high-risk postmenopausal women (IBIS-II): an international, double-blind, randomised placebo-controlled trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Double-Blind Method; Female; Humans; Longitudinal Studies; Middle Aged; Nitriles; Postmenopause; Proportional Hazards Models; Risk Factors; Treatment Outcome; Triazoles | 2014 |
Testosterone with dutasteride, but not anastrazole, improves insulin sensitivity in young obese men: a randomized controlled trial.
Topics: 5-alpha Reductase Inhibitors; Absorptiometry, Photon; Adult; Anastrozole; Azasteroids; Body Composition; Body Mass Index; Dihydrotestosterone; Double-Blind Method; Drug Therapy, Combination; Dutasteride; Estradiol; Humans; Insulin Resistance; Male; Middle Aged; Nitriles; Obesity; Testosterone; Triazoles; Young Adult | 2014 |
COMPliance and Arthralgia in Clinical Therapy: the COMPACT trial, assessing the incidence of arthralgia, and compliance within the first year of adjuvant anastrozole therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Substitution; Female; Humans; Incidence; Medication Adherence; Middle Aged; Nitriles; Prospective Studies; Treatment Outcome; Triazoles | 2014 |
Effects of adjuvant exemestane versus anastrozole on bone mineral density for women with early breast cancer (MA.27B): a companion analysis of a randomised controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bones of Lower Extremity; Breast Neoplasms; Calcium; Canada; Chemotherapy, Adjuvant; Dietary Supplements; Diphosphonates; Female; Fractures, Bone; Humans; Lumbar Vertebrae; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Radiography; Time Factors; Treatment Outcome; Triazoles; United States; Vitamin D | 2014 |
A pilot study comparing the effect of flaxseed, aromatase inhibitor, and the combination on breast tumor biomarkers.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Estrogen Receptor beta; Female; Flax; Gonadal Steroid Hormones; Humans; Lignans; Linear Models; Middle Aged; Nitriles; Pilot Projects; Treatment Outcome; Triazoles; Young Adult | 2014 |
The impact of educational materials on compliance and persistence rates with adjuvant aromatase inhibitor treatment: first-year results from the compliance of aromatase inhibitors assessment in daily practice through educational approach (CARIATIDE) study
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Lymph Node Excision; Mastectomy; Medication Adherence; Middle Aged; Nitriles; Patient Education as Topic; Postmenopause; Triazoles | 2014 |
Pilot randomised study of early intervention based on tumour markers in the follow-up of patients with primary breast cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoembryonic Antigen; Early Detection of Cancer; Female; Follow-Up Studies; Goserelin; Humans; Liver Neoplasms; Lung Neoplasms; Middle Aged; Mucin-1; Nitriles; Pilot Projects; Single-Blind Method; Tamoxifen; Treatment Outcome; Triazoles | 2014 |
Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Everolimus; Female; Genital Neoplasms, Female; Humans; Kaplan-Meier Estimate; Middle Aged; Nitriles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Treatment Outcome; Triazoles; Young Adult | 2014 |
A prospective, randomized study on hepatotoxicity of anastrozole compared with tamoxifen in women with breast cancer.
Topics: Aged; Anastrozole; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Fatty Liver; Female; Humans; Liver; Middle Aged; Nitriles; Prospective Studies; Tamoxifen; Treatment Failure; Triazoles | 2014 |
Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; ErbB Receptors; Female; Gefitinib; Humans; Ki-67 Antigen; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Nitriles; Phosphatidylinositol 3-Kinases; Prognosis; Protein Kinase Inhibitors; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; TOR Serine-Threonine Kinases; Triazoles | 2014 |
Electroacupuncture for fatigue, sleep, and psychological distress in breast cancer patients with aromatase inhibitor-related arthralgia: a randomized trial.
Topics: Aged; Anastrozole; Androstadienes; Anxiety; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Depression; Electroacupuncture; Fatigue; Female; Humans; Letrozole; Middle Aged; Nitriles; Quality of Life; Sleep Wake Disorders; Stress, Psychological; Treatment Outcome; Triazoles | 2014 |
Effect of calcitonin on anastrozole-induced bone pain during aromatase inhibitor therapy for breast cancer.
Topics: Absorptiometry, Photon; Aged; Alkaline Phosphatase; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Calcitonin; Calcium; Female; Femur; Humans; Middle Aged; Nitriles; Osteocalcin; Osteoporosis; Pain; Phosphorus; Spine; Triazoles | 2014 |
Letrozole vs anastrozole for height augmentation in short pubertal males: first year data.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Body Height; Child; Estradiol; Growth Disorders; Humans; Letrozole; Luteinizing Hormone; Male; Nitriles; Puberty; Testosterone; Treatment Outcome; Triazoles | 2014 |
Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density; Female; Gene-Environment Interaction; Genome-Wide Association Study; Genotype; Humans; Middle Aged; Nitriles; Osteoporosis; Osteoporotic Fractures; Polymorphism, Single Nucleotide; Triazoles | 2014 |
Estrogens and their precursors in postmenopausal women with early breast cancer receiving anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Middle Aged; Nitriles; Postmenopause; Testosterone; Triazoles | 2015 |
Anastrozole versus tamoxifen as adjuvant therapy for Japanese postmenopausal patients with hormone-responsive breast cancer: efficacy results of long-term follow-up data from the N-SAS BC 03 trial.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Female; Follow-Up Studies; Humans; Immunoenzyme Techniques; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Tamoxifen; Triazoles | 2014 |
Prediction of late distant recurrence after 5 years of endocrine treatment: a combined analysis of patients from the Austrian breast and colorectal cancer study group 8 and arimidex, tamoxifen alone or in combination randomized trials using the PAM50 risk
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Austria; Breast Neoplasms; Data Interpretation, Statistical; Female; Follow-Up Studies; Hormones; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Prognosis; Proportional Hazards Models; Regression Analysis; Risk; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2015 |
Zoledronic acid combined with adjuvant endocrine therapy of tamoxifen versus anastrozol plus ovarian function suppression in premenopausal early breast cancer: final analysis of the Austrian Breast and Colorectal Cancer Study Group Trial 12.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Disease-Free Survival; Female; Follow-Up Studies; Goserelin; Humans; Imidazoles; Kaplan-Meier Estimate; Middle Aged; Nitriles; Premenopause; Tamoxifen; Triazoles; Zoledronic Acid | 2015 |
Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial.
Topics: Adult; Aged; Anastrozole; Bone Density; Bone Density Conservation Agents; Double-Blind Method; Etidronic Acid; Female; Follow-Up Studies; Humans; International Agencies; Middle Aged; Nitriles; Osteoporosis; Postmenopause; Prognosis; Risedronic Acid; Triazoles | 2014 |
Treatment-associated musculoskeletal and vasomotor symptoms and relapse-free survival in the NCIC CTG MA.27 adjuvant breast cancer aromatase inhibitor trial.
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Hot Flashes; Humans; Kaplan-Meier Estimate; Middle Aged; Musculoskeletal System; Nitriles; Triazoles; Vasomotor System | 2015 |
Does patient education work in breast cancer? Final results from the global CARIATIDE study.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Patient Compliance; Patient Education as Topic; Tamoxifen; Triazoles | 2015 |
Electroretinographic and optical coherence tomography findings in breast cancer patients using aromatase inhibitors.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Electroretinography; Evoked Potentials, Visual; Female; Humans; Letrozole; Middle Aged; Nerve Fibers; Nitriles; Optic Nerve; Retina; Tomography, Optical Coherence; Triazoles; Visual Acuity | 2016 |
Evaluating the feasibility of performing window of opportunity trials in breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Drug Administration Schedule; Feasibility Studies; Female; Humans; Mastectomy; Middle Aged; Neoadjuvant Therapy; Nitriles; Pilot Projects; Prospective Studies; Triazoles | 2015 |
Joint symptoms and health-related quality of life in postmenopausal women with breast cancer who completed 5 years of anastrozole.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Joint Diseases; Middle Aged; Nitriles; Postmenopause; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Triazoles | 2016 |
A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cognition Disorders; Female; Humans; Letrozole; Memory; Middle Aged; Nitriles; Postmenopause; Psychomotor Performance; Quality of Life; Tamoxifen; Triazoles | 2015 |
Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 2015 |
A Randomized Prospective Double-Blind Comparison Trial of Clomiphene Citrate and Anastrozole in Raising Testosterone in Hypogonadal Infertile Men.
Topics: Anastrozole; Clomiphene; Double-Blind Method; Fertility Agents, Male; Follicle Stimulating Hormone; Hormones; Humans; Hypogonadism; Infertility, Male; Luteinizing Hormone; Male; Nitriles; Prospective Studies; Testosterone; Treatment Outcome; Triazoles | 2015 |
[BREAST-CONSERVING SURGERY AFTER NEOADJUVANT THERAPY FOR BREAST CANCER].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Doxorubicin; Everolimus; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoadjuvant Therapy; Nitriles; Paclitaxel; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Sirolimus; TOR Serine-Threonine Kinases; Trastuzumab; Treatment Outcome; Triazoles | 2015 |
Fulvestrant 500 mg Versus Anastrozole 1 mg for the First-Line Treatment of Advanced Breast Cancer: Overall Survival Analysis From the Phase II FIRST Study.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Drug Administration Schedule; Estradiol; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Kaplan-Meier Estimate; Middle Aged; Nitriles; Treatment Outcome; Triazoles | 2015 |
Anastrozole plus leuprorelin in early maturing girls with compromised growth: the "GAIL" study.
Topics: Anastrozole; Aromatase Inhibitors; Body Height; Bone Density; Case-Control Studies; Child; Female; Follow-Up Studies; Gonadotropin-Releasing Hormone; Greece; Growth Disorders; Humans; Leuprolide; Nitriles; Prognosis; Prospective Studies; Puberty, Precocious; Sexual Maturation; Triazoles | 2016 |
Effects of aromatase inhibition vs. testosterone in older men with low testosterone: randomized-controlled trial.
Topics: Aged; Aged, 80 and over; Aging; Anastrozole; Aromatase; Aromatase Inhibitors; Body Composition; Bone and Bones; Bone Density; Double-Blind Method; Estradiol; Humans; Male; Nitriles; Placebos; Testosterone; Triazoles | 2016 |
Anastrozole-Induced Carpal Tunnel Syndrome: Results From the International Breast Cancer Intervention Study II Prevention Trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carpal Tunnel Syndrome; Double-Blind Method; Female; Humans; Incidence; International Cooperation; Middle Aged; Nitriles; Odds Ratio; Risk Factors; Severity of Illness Index; Triazoles | 2016 |
Anastrozole versus tamoxifen for the prevention of locoregional and contralateral breast cancer in postmenopausal women with locally excised ductal carcinoma in situ (IBIS-II DCIS): a double-blind, randomised controlled trial.
Topics: Administration, Oral; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Double-Blind Method; Female; Humans; Intention to Treat Analysis; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2016 |
Anastrozole versus tamoxifen in postmenopausal women with ductal carcinoma in situ undergoing lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial.
Topics: Administration, Oral; Age Factors; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Double-Blind Method; Embolism; Female; Humans; Mastectomy, Segmental; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Thrombosis; Triazoles | 2016 |
Patient-reported outcomes with anastrozole versus tamoxifen for postmenopausal patients with ductal carcinoma in situ treated with lumpectomy plus radiotherapy (NSABP B-35): a randomised, double-blind, phase 3 clinical trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Double-Blind Method; Female; Follow-Up Studies; Humans; Mastectomy, Segmental; Middle Aged; Nitriles; Postmenopause; Quality of Life; Tamoxifen; Triazoles | 2016 |
A European Organisation for Research and Treatment of Cancer randomized, double-blind, placebo-controlled, multicentre phase II trial of anastrozole in combination with gefitinib or placebo in hormone receptor-positive advanced breast cancer (NCT00066378)
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Double-Blind Method; Early Termination of Clinical Trials; Female; Gefitinib; Humans; Middle Aged; Nitriles; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome; Triazoles | 2016 |
A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor-Positive Metastatic Breast Cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Drug Synergism; Estradiol; Female; Fulvestrant; Heterocyclic Compounds, 3-Ring; Humans; Hyperglycemia; Hypoglycemic Agents; Maximum Tolerated Dose; Middle Aged; Nitriles; Proto-Oncogene Proteins c-akt; Receptors, Estrogen; Treatment Outcome; Triazoles | 2016 |
Fulvestrant decreases anastrozole drug concentrations when taken concurrently by patients with metastatic breast cancer treated on SWOG study S0226.
Topics: Anastrozole; Breast Neoplasms; Drug Interactions; Estradiol; Female; Fulvestrant; Humans; Nitriles; Triazoles | 2016 |
Randomized, blinded trial of vitamin D3 for treating aromatase inhibitor-associated musculoskeletal symptoms (AIMSS).
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Bone Density; Breast Neoplasms; Cholecalciferol; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Letrozole; Middle Aged; Musculoskeletal Diseases; Nitriles; Triazoles; Vitamin D | 2016 |
Effects of Transdermal Testosterone Gel or an Aromatase Inhibitor on Prostate Volume in Older Men.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Double-Blind Method; Humans; Male; Nitriles; Organ Size; Prostate; Testosterone; Treatment Outcome; Triazoles; Ultrasonography | 2016 |
Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men.
Topics: Adolescent; Adult; Anastrozole; Aromatase Inhibitors; Cross-Over Studies; Double-Blind Method; Estradiol; Glucose; Glucose Clamp Technique; Healthy Volunteers; Humans; Insulin Resistance; Lipolysis; Liver; Male; Middle Aged; Muscle, Skeletal; Nitriles; Testosterone; Triazoles; Young Adult | 2016 |
Phase II Randomized Preoperative Window-of-Opportunity Study of the PI3K Inhibitor Pictilisib Plus Anastrozole Compared With Anastrozole Alone in Patients With Estrogen Receptor-Positive Breast Cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Combined Modality Therapy; Drug Synergism; Female; Humans; Indazoles; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Postmenopause; Preoperative Care; Protein Kinase Inhibitors; Receptor, ErbB-2; Receptors, Estrogen; Sulfonamides; Triazoles | 2016 |
Competing risks of death in women treated with adjuvant aromatase inhibitors for early breast cancer on NCIC CTG MA.27.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cardiovascular Diseases; Cause of Death; Chemotherapy, Adjuvant; Comorbidity; Female; Humans; Middle Aged; Nitriles; Postmenopause; Survival Analysis; Treatment Outcome; Triazoles | 2016 |
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disease-Free Survival; DNA, Neoplasm; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Piperazines; Prospective Studies; Pyridines; Retrospective Studies; Triazoles | 2016 |
Randomized phase 2 neoadjuvant trial evaluating anastrozole and fulvestrant efficacy for postmenopausal, estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer patients: Results of the UNICANCER CARMINA 02 French trial
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Estradiol; Female; Follow-Up Studies; France; Fulvestrant; Humans; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Survival Rate; Triazoles | 2016 |
Pharmacokinetics, pharmacodynamics, safety and tolerability of an intravaginal ring releasing anastrozole and levonorgestrel in healthy premenopausal women: a Phase 1 randomized controlled trial.
Topics: Administration, Intravaginal; Adult; Anastrozole; Aromatase Inhibitors; Endometriosis; Estradiol; Female; Healthy Volunteers; Humans; Levonorgestrel; Nitriles; Ovarian Follicle; Premenopause; Triazoles; Women's Health; Young Adult | 2016 |
Endogenous Estrogen Regulates Somatostatin-Induced Rebound GH Secretion in Postmenopausal Women.
Topics: Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Double-Blind Method; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Fulvestrant; Human Growth Hormone; Humans; Middle Aged; Nitriles; Postmenopause; Somatostatin; Triazoles | 2016 |
Anastrozole in Pulmonary Arterial Hypertension. A Randomized, Double-Blind, Placebo-controlled Trial.
Topics: Anastrozole; Aromatase Inhibitors; Biomarkers; Double-Blind Method; Estradiol; Estrone; Female; Gonadal Steroid Hormones; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nitriles; Progesterone; Steroids; Triazoles | 2017 |
Inhibition of EGFR, HER2, and HER3 signaling with AZD8931 in combination with anastrozole as an anticancer approach: Phase II randomized study in women with endocrine-therapy-naïve advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; ErbB Receptors; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Nitriles; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Retreatment; Signal Transduction; Treatment Outcome; Triazoles | 2016 |
Randomized Trial of Aromatase Inhibitors, Growth Hormone, or Combination in Pubertal Boys with Idiopathic, Short Stature.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Body Composition; Body Height; Drug Therapy, Combination; Dwarfism; Growth Hormone; Humans; Letrozole; Male; Nitriles; Outcome Assessment, Health Care; Puberty; Triazoles | 2016 |
Chemosensitivity and Endocrine Sensitivity in Clinical Luminal Breast Cancer Patients in the Prospective Neoadjuvant Breast Registry Symphony Trial (NBRST) Predicted by Molecular Subtyping.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Bridged-Ring Compounds; Chemotherapy, Adjuvant; Clinical Decision-Making; Cyclophosphamide; Docetaxel; Doxorubicin; Female; Gene Expression Profiling; Humans; Immunohistochemistry; In Situ Hybridization, Fluorescence; Letrozole; Mastectomy, Segmental; Middle Aged; Molecular Typing; Neoadjuvant Therapy; Nitriles; Prospective Studies; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Registries; Tamoxifen; Taxoids; Treatment Outcome; Triazoles; Young Adult | 2017 |
Fulvestrant 500 mg versus anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON): an international, randomised, double-blind, phase 3 trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast; Breast Neoplasms; Disease-Free Survival; Double-Blind Method; Estradiol; Female; Fulvestrant; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2016 |
Model-Based Dose Selection for Intravaginal Ring Formulations Releasing Anastrozole and Levonorgestrel Intended for the Treatment of Endometriosis Symptoms.
Topics: Administration, Intravaginal; Adult; Anastrozole; Computer Simulation; Contraceptive Agents, Female; Drug Combinations; Drug Interactions; Endometriosis; Estradiol; Female; Humans; Levonorgestrel; Models, Biological; Nitriles; Ovarian Follicle; Sex Hormone-Binding Globulin; Triazoles; Young Adult | 2017 |
Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Decision-Making; Female; Follow-Up Studies; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Mitotic Index; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Transcriptome; Triazoles | 2017 |
Comparative Efficacy and Safety of Adjuvant Letrozole Versus Anastrozole in Postmenopausal Patients With Hormone Receptor-Positive, Node-Positive Early Breast Cancer: Final Results of the Randomized Phase III Femara Versus Anastrozole Clinical Evaluation
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Depression; Disease-Free Survival; Dyspnea; Female; Hot Flashes; Humans; Hypertension; Letrozole; Lymphatic Metastasis; Mastectomy; Middle Aged; Myalgia; Neoplasm Staging; Nitriles; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; Triazoles | 2017 |
Osteoporosis therapy and outcomes for postmenopausal patients with hormone receptor-positive breast cancer: NCIC CTG MA.27.
Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Disease-Free Survival; Female; Humans; Male; Mastectomy; Middle Aged; Multivariate Analysis; Nitriles; Osteoporosis, Postmenopausal; Proportional Hazards Models; Radiotherapy, Adjuvant; Receptors, Estrogen; Treatment Outcome; Triazoles | 2017 |
Paragon (ANZGOG-0903): Phase 2 Study of Anastrozole in Women With Estrogen or Progesterone Receptor-Positive Platinum-Resistant or -Refractory Recurrent Ovarian Cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Carcinoma, Ovarian Epithelial; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Nitriles; Organoplatinum Compounds; Ovarian Neoplasms; Prospective Studies; Quality of Life; Receptors, Estrogen; Receptors, Progesterone; Tissue Array Analysis; Triazoles | 2017 |
Impact of nonsteroidal aromatase inhibitors on steroid profile in a Chinese population.
Topics: Aminoglutethimide; Anastrozole; Aromatase Inhibitors; Biomarkers, Pharmacological; Doping in Sports; Female; Hormones; Humans; Letrozole; Male; Models, Biological; Nitriles; Single-Blind Method; Steroids; Substance-Related Disorders; Triazoles; Young Adult | 2017 |
Absence of Effect of Intravaginal Miconazole, Clindamycin, Nonoxynol-9, and Tampons on the Pharmacokinetics of an Anastrozole/Levonorgestrel Intravaginal Ring.
Topics: Administration, Intravaginal; Adult; Anastrozole; Anti-Bacterial Agents; Antifungal Agents; Clindamycin; Contraceptives, Oral, Combined; Endometriosis; Female; Humans; Levonorgestrel; Menstrual Hygiene Products; Miconazole; Nitriles; Nonoxynol; Triazoles | 2018 |
MONARCH 3: Abemaciclib As Initial Therapy for Advanced Breast Cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminopyridines; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzimidazoles; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptor, ErbB-2; Survival Rate; Treatment Outcome; Triazoles | 2017 |
Extended adjuvant aromatase inhibition after sequential endocrine therapy (DATA): a randomised, phase 3 trial.
Topics: Administration, Oral; Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Kaplan-Meier Estimate; Mastectomy; Maximum Tolerated Dose; Middle Aged; Netherlands; Nitriles; Postmenopause; Prognosis; Prospective Studies; Receptor, ErbB-2; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2017 |
Comparison of pharmacokinetics of newly discovered aromatase inhibitors by a cassette microdosing approach in healthy Japanese subjects.
Topics: Administration, Intravenous; Administration, Oral; Aged; Anastrozole; Aniline Compounds; Animals; Aromatase; Aromatase Inhibitors; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Discovery; Healthy Volunteers; Humans; Japan; Male; Molecular Structure; Nitriles; Rats; Structure-Activity Relationship; Triazoles | 2017 |
Effect of Antiandrogen, Aromatase Inhibitor, and Gonadotropin-releasing Hormone Analog on Adult Height in Familial Male Precocious Puberty.
Topics: Adult; Anastrozole; Androgen Antagonists; Aromatase Inhibitors; Body Height; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Gonadotropin-Releasing Hormone; Humans; Leuprolide; Male; Nitriles; Puberty, Precocious; Spironolactone; Testolactone; Treatment Outcome; Triazoles; Triptorelin Pamoate | 2017 |
Outcomes in women with invasive ductal or invasive lobular early stage breast cancer treated with anastrozole or exemestane in CCTG (NCIC CTG) MA.27.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Disease-Free Survival; Female; Humans; Middle Aged; Nitriles; Treatment Outcome; Triazoles | 2018 |
Progression-free survival results in postmenopausal Asian women: subgroup analysis from a phase III randomized trial of fulvestrant 500 mg vs anastrozole 1 mg for hormone receptor-positive advanced breast cancer (FALCON).
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast; Breast Neoplasms; China; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Japan; Middle Aged; Nitriles; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Response Evaluation Criteria in Solid Tumors; Taiwan; Triazoles | 2018 |
Postoperative Adjuvant Anastrozole for 10 or 5 Years in Patients With Hormone Receptor-Positive Breast Cancer: AERAS, a Randomized Multicenter Open-Label Phase III Trial.
Topics: Adjuvants, Immunologic; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Neoplasm Recurrence, Local; Neoplasms, Second Primary; Nitriles; Prospective Studies; Tamoxifen; Triazoles | 2023 |
678 other study(ies) available for anastrozole and triazoles
| Article | Year |
|---|---|
Arimidex: a potent and selective fourth-generation aromatase inhibitor.
Topics: Administration, Oral; Anastrozole; Animals; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Dogs; Estrogens; Female; Hormones; In Vitro Techniques; Macaca nemestrina; Male; Nitriles; Postmenopause; Rats; Triazoles | 1994 |
Anastrozole for metastatic breast cancer.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Neoplasm Metastasis; Nitriles; Triazoles | 1996 |
New aromatase inhibitors: more selectivity, less toxicity, unfortunately, the same activity.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Nitriles; Triazoles | 1996 |
Aromatase inhibitors in metastatic breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Fadrozole; Female; Humans; Megestrol Acetate; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Triazoles | 1996 |
The preclinical pharmacology of "Arimidex" (anastrozole; ZD1033)--a potent, selective aromatase inhibitor.
Topics: Adrenal Glands; Aminoglutethimide; Anastrozole; Androstenedione; Animals; Aromatase Inhibitors; Cortodoxone; Enzyme Inhibitors; Fadrozole; Female; Hormones; Humans; Macaca nemestrina; Male; Metyrapone; Nitriles; Organ Size; Potassium; Prostate; Rats; Rats, Wistar; Seminal Vesicles; Sodium; Triazoles; Uterus | 1996 |
Role of new selective aromatase inhibitor in therapy for metastatic breast cancer in postmenopausal women.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 1997 |
Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromatase.
Topics: Anastrozole; Aromatase Inhibitors; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Nifedipine; Nitriles; Oxidoreductases, N-Demethylating; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Substrate Specificity; Triazoles | 1997 |
Fetal death in mice lacking 5alpha-reductase type 1 caused by estrogen excess.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anastrozole; Androstenedione; Animals; Biological Assay; Decidua; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Estrogen Antagonists; Estrogens; Female; Fetal Death; Gene Expression Regulation, Enzymologic; In Situ Hybridization; Litter Size; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitriles; Placenta; RNA, Messenger; Steroids; Tamoxifen; Triazoles; Uterus | 1997 |
Aromatase inhibitors come of age.
Topics: Aminoglutethimide; Anastrozole; Androstenedione; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Female; Humans; Letrozole; Nitriles; Triazoles | 1997 |
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured | 1997 |
Predictors of response to second-line endocrine therapy for breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Gonanes; Goserelin; Humans; Megestrol Acetate; Middle Aged; Nitriles; Ovariectomy; Predictive Value of Tests; Remission Induction; Tamoxifen; Triazoles | 1997 |
The weanling male rat as an assay for endocrine disruption: preliminary observations.
Topics: Anastrozole; Androgen Antagonists; Animals; Body Weight; Cyproterone Acetate; Drug Evaluation, Preclinical; Endocrine System Diseases; Female; Lactose; Male; Methylcellulose; Nitriles; Organ Size; Oxazines; Oxazoles; Rats; Rats, Inbred Strains; Toxicology; Triazoles; Uterus; Weaning | 1997 |
Physiological plasma levels of androgens reduce bone loss in the ovariectomized rat.
Topics: Aging; Anastrozole; Androgen Antagonists; Androstenedione; Anilides; Animals; Body Weight; Bone Resorption; Enzyme Inhibitors; Estradiol; Female; Nitriles; Ovariectomy; Rats; Rats, Sprague-Dawley; Testosterone; Tosyl Compounds; Triazoles | 1998 |
[Two new therapeutic principles in the management of breast cancer and colorectal cancer: selective oral aromatase inhibition and thymidilate synthase inhibition].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Colorectal Neoplasms; Enzyme Inhibitors; Female; Humans; Male; Nitriles; Palliative Care; Triazoles | 1997 |
Treatment of severe postmenopausal endometriosis with an aromatase inhibitor.
Topics: Administration, Oral; Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Biopsy; Endometriosis; Enzyme Inhibitors; Female; Humans; Middle Aged; Nitriles; Polymerase Chain Reaction; Postmenopause; Rats; Recurrence; RNA, Messenger; Time Factors; Triazoles | 1998 |
Preclinical studies using the intratumoral aromatase model for postmenopausal breast cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Drug Screening Assays, Antitumor; Endometrial Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Hormone-Dependent; Nitriles; Organ Size; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles; Tumor Cells, Cultured; Uterus | 1998 |
Aromatase inhibitors and their future role in post-menopausal women with early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogens; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 1998 |
Effect of dual inhibition of 5-alpha-reductase and aromatase on spontaneously developed canine prostatic hypertrophy.
Topics: Anastrozole; Animals; Aromatase; Cholestenone 5 alpha-Reductase; Dihydrotestosterone; Dogs; Enzyme Inhibitors; Finasteride; Male; Nitriles; Oxidoreductases; Prostate; Prostatic Hyperplasia; Testosterone; Triazoles | 1998 |
The effects of aromatase inhibitors and antiestrogens in the nude mouse model.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Nitriles; Tamoxifen; Triazoles; Tumor Cells, Cultured | 1998 |
The steroidal antiestrogen ICI 182,780 is an inhibitor of cellular aromatase activity.
Topics: Anastrozole; Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Breast Neoplasms; Cell Division; Cells, Cultured; Choriocarcinoma; DNA Primers; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fibroblasts; Fulvestrant; Humans; Letrozole; Microsomes; Nitriles; Placenta; RNA, Messenger; Triazoles; Tumor Cells, Cultured | 1998 |
Macrophage colony stimulating-factor transcripts are differentially regulated in rat bone-marrow by gender hormones.
Topics: Anastrozole; Androgen Antagonists; Androstenedione; Anilides; Animals; Bone Marrow; Enzyme Inhibitors; Estradiol; Estrogens; Female; Gene Expression Regulation; Macrophage Colony-Stimulating Factor; Molecular Weight; Nitriles; Ovariectomy; Polymerase Chain Reaction; Radioimmunoassay; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sex Characteristics; Tosyl Compounds; Transcription, Genetic; Triazoles | 1999 |
Mitogenic and antioxidant mechanisms of estradiol action in preovulatory ovine follicles: relevance to luteal function.
Topics: Anastrozole; Animals; Antioxidants; Apoptosis; Aromatase Inhibitors; Corpus Luteum; DNA Fragmentation; Enzyme Inhibitors; Estradiol; Female; Mitosis; Nitriles; Ovarian Follicle; Oxidative Stress; Progesterone; Proliferating Cell Nuclear Antigen; Sheep; Triazoles | 1999 |
Assessment of quality of life in women undergoing hormonal therapy for breast cancer: validation of an endocrine symptom subscale for the FACT-B.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Evaluation Studies as Topic; Female; Hormone Replacement Therapy; Humans; Megestrol Acetate; Menopause; Middle Aged; Nitriles; Pilot Projects; Quality of Life; Surveys and Questionnaires; Tamoxifen; Time Factors; Triazoles | 1999 |
5alpha-reductase isozymes and aromatase are differentially expressed and active in the androgen-independent human prostate cancer cell lines DU145 and PC3.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Anastrozole; Androgens; Androstenedione; Aromatase; Aromatase Inhibitors; Blotting, Southern; Dihydrotestosterone; Enzyme Inhibitors; Etiocholanolone; Humans; Hydrogen-Ion Concentration; Isoenzymes; Male; Microsomes; Nitriles; Prostatic Hyperplasia; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Testosterone; Triazoles; Tumor Cells, Cultured | 1999 |
The effect of combining aromatase inhibitors with antiestrogens on tumor growth in a nude mouse model for breast cancer.
Topics: Analysis of Variance; Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Disease Models, Animal; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Tamoxifen; Time Factors; Triazoles; Tumor Cells, Cultured | 1999 |
Safety and tolerability of endocrine therapies used in the treatment of advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Tolerance; Female; Humans; Megestrol Acetate; Nitriles; Safety; Tamoxifen; Triazoles | 1999 |
Future directions in endocrine treatment of advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Megestrol Acetate; Nitriles; Tamoxifen; Triazoles | 1999 |
Effect of chronic administration of an aromatase inhibitor to adult male rats on pituitary and testicular function and fertility.
Topics: Anastrozole; Animals; Copulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fertility; Follicle Stimulating Hormone; Male; Nitriles; Organ Size; Rats; Rats, Wistar; Spermatogenesis; Testis; Testosterone; Triazoles | 2000 |
A novel HPLC-RIA method for the simultaneous detection of estrone, estradiol and estrone sulphate levels in breast cancer tissue.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrone; Female; Humans; Nitriles; Postmenopause; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Triazoles | 2000 |
Effects of the aromatase inhibitor anastrozole on serum oestrogens in Japanese and Caucasian women.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Asian People; Breast Neoplasms; Enzyme Inhibitors; Estradiol; Estrogens; Estrone; Female; Humans; Japan; Middle Aged; Nitriles; Triazoles; White People | 2000 |
[Aromatase inhibitors in the treatment of breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2000 |
Cost-utility analysis of second-line hormonal therapy in advanced breast cancer: a comparison of two aromatase inhibitors to megestrol acetate.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Costs and Cost Analysis; Decision Support Techniques; Female; Humans; Letrozole; Megestrol Acetate; Nitriles; Quality of Life; Randomized Controlled Trials as Topic; Triazoles | 2000 |
An overview of the use of non-steroidal aromatase inhibitors in the treatment of breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Triazoles | 2000 |
Gonadotropins stimulate growth of MCF-7 human breast cancer cells by promoting intracellular conversion of adrenal androgens to estrogens.
Topics: Anastrozole; Androgens; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Chorionic Gonadotropin, beta Subunit, Human; Dehydroepiandrosterone; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Fulvestrant; Humans; Nitriles; Triazoles; Tumor Cells, Cultured | 2000 |
Endocrine options for breast cancer treatment: looking beyond tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Goserelin; Humans; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2000 |
Clarification of anastrozole/megestrol acetate trial program design.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Female; Humans; Megestrol Acetate; Nitriles; Prospective Studies; Research Design; Triazoles | 2000 |
The uterotrophic activity of nonylphenol in the rat is not mediated by aromatase enzyme induction.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Enzyme Induction; Enzyme Inhibitors; Female; Nitriles; Organ Size; Phenols; Rats; Rats, Wistar; Receptors, Estrogen; Tetrahydronaphthalenes; Triazoles; Uterus | 2001 |
Clinical trials in cancer: what makes for a successful study?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Drug Industry; Female; Humans; Interinstitutional Relations; Mastectomy; Medical Audit; Motivation; Multicenter Studies as Topic; Nitriles; Patient Selection; Patients; Physician-Patient Relations; Prospective Studies; Randomized Controlled Trials as Topic; Research Design; Tamoxifen; Triazoles | 2000 |
Drug approval summaries: arsenic trioxide, tamoxifen citrate, anastrazole, paclitaxel, bexarotene.
Topics: Anastrozole; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Arsenic Trioxide; Arsenicals; Bexarotene; Breast Neoplasms; Drug Approval; Female; Humans; Leukemia, Promyelocytic, Acute; Lymphoma, T-Cell, Cutaneous; Nitriles; Oxides; Paclitaxel; Tamoxifen; Tetrahydronaphthalenes; Triazoles; United States; United States Food and Drug Administration | 2001 |
Delayed closure of epiphyseal cartilages induced by the aromatase inhibitor anastrozole. Would it help short children grow up?
Topics: Anastrozole; Aromatase Inhibitors; Body Height; Bone Development; Child, Preschool; Enzyme Inhibitors; Growth Disorders; Growth Plate; Human Growth Hormone; Humans; Male; Nitriles; Puberty, Precocious; Triazoles | 2000 |
Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Dexamethasone; Enzyme Inhibitors; Estrogen Antagonists; Feedback; Follicle Stimulating Hormone; Glucocorticoids; Gonadal Steroid Hormones; Gonadotropins; Humans; Ketoconazole; Luteinizing Hormone; Male; Nitriles; Testosterone; Triazoles | 2001 |
Estrogenic upregulation of DNA polymerase beta in oocytes of preovulatory ovine follicles.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Blastocyst; Corpus Luteum; Dactinomycin; Dinoprost; DNA Polymerase beta; DNA Repair; Drug Administration Schedule; Enzyme Induction; Enzyme Inhibitors; Estradiol; Estrus; Female; Follicular Phase; Gonadotropins; Meiosis; Nitriles; Nucleic Acid Synthesis Inhibitors; Oocytes; Ovarian Follicle; Ovulation Induction; Sheep; Triazoles | 2001 |
The Twenty-third Annual San Antonio Breast Cancer Symposium.
Topics: Anastrozole; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Capecitabine; Combined Modality Therapy; Deoxycytidine; Estradiol; Estrogen Antagonists; Female; Fluorouracil; Fulvestrant; Humans; Letrozole; Male; Mastectomy; Nitriles; Prognosis; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2001 |
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Is anastrozole superior to tamoxifen as first-line therapy for advanced breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2001 |
Aromatase inhibitors and arthralgia.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 2001 |
The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Biomarkers; Bone Density; Bone Remodeling; Enzyme Inhibitors; Gonadal Steroid Hormones; Gonadotropins; Humans; Lipids; Male; Nitriles; Triazoles | 2001 |
Aromatase inhibitors and inactivators in breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2001 |
HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Female; Gene Amplification; Humans; Immunohistochemistry; Ki-67 Antigen; Multicenter Studies as Topic; Nitriles; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Tamoxifen; Triazoles | 2001 |
[Clinical study of anastrozole in the treatment of postmenopausal women with advanced breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 1999 |
Aromatase inhibitors for male infertility.
Topics: Anastrozole; Aromatase Inhibitors; Enzyme Inhibitors; Estradiol; Humans; Infertility, Male; Klinefelter Syndrome; Liver Function Tests; Male; Nitriles; Sperm Motility; Testolactone; Testosterone; Triazoles | 2002 |
Formestane, a steroidal aromatase inhibitor after failure of non-steroidal aromatase inhibitors (anastrozole and letrozole): is a clinical benefit still achievable?
Topics: Adult; Aged; Anastrozole; Androstenedione; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Enzyme Inhibitors; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Retrospective Studies; Treatment Failure; Triazoles | 2001 |
World's largest breast cancer treatment trial supports anastrozole use.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Multicenter Studies as Topic; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2002 |
Local endocrine effects of aromatase inhibitors within the breast.
Topics: Anastrozole; Androstadienes; Aromatase; Aromatase Inhibitors; Breast; Breast Neoplasms; Cells, Cultured; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogens; Estrone; Female; Fibroblasts; Humans; In Vitro Techniques; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2001 |
Biological and clinical effects of aromatase inhibitors in neoadjuvant therapy.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Letrozole; Menopause; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2001 |
[Aromatase inhibitors of the 3rd generation. What can the "pill against breast cancer" really do?].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Humans; Letrozole; Nitriles; Triazoles | 2002 |
Effects of aromatase inhibition on in vitro follicle and oocyte development analyzed by early preantral mouse follicle culture.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Cells, Cultured; Enzyme Inhibitors; Estradiol; Female; Meiosis; Metaphase; Mice; Mice, Inbred C57BL; Nitriles; Oocytes; Ovarian Follicle; Progesterone; Spindle Apparatus; Testosterone; Triazoles | 2002 |
Hormones 'R' us.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Antagonists; Female; Humans; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2002 |
Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Arteriosclerosis; Cell Adhesion; Dihydrotestosterone; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Fulvestrant; Gene Expression Regulation; Humans; Male; Mice; Nitriles; Receptors, Estrogen; RNA, Messenger; Testosterone; Triazoles; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2002 |
Experience of hormonal therapy with anastrozole for previously treated metastatic breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Retrospective Studies; Survival Analysis; Triazoles | 2002 |
New breast cancer drugs expand treatment options.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2002 |
Comparison of in vitro exemestane activity versus other antiaromatase agents.
Topics: Aminoglutethimide; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Choriocarcinoma; Female; Humans; Nitriles; Triazoles; Tumor Cells, Cultured | 2000 |
Short-term effects of anastrozole treatment on insulin-like growth factor system in postmenopausal advanced breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Letrozole; Middle Aged; Nitriles; Postmenopause; Time Factors; Triazoles | 2002 |
A better medication for treating breast cancer?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2002 |
Efficacy of anastrozole in male breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms, Male; Combined Modality Therapy; Enzyme Inhibitors; Humans; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nitriles; Treatment Failure; Triazoles | 2002 |
The oncology nurse's role in educating patients on endocrine therapy for metastatic breast cancer--focus on fulvestrant.
Topics: Administration, Oral; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estrogen Receptor Modulators; Female; Humans; Injections, Intramuscular; Nitriles; Nurse's Role; Oncology Nursing; Patient Education as Topic; Triazoles | 2002 |
Endocrine effects of nonsteroidal aromatase inhibitors and their clinical impact.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cross-Over Studies; Enzyme Inhibitors; Estrogens; Female; Humans; Letrozole; Nitriles; Postmenopause; Research Design; Triazoles | 2002 |
Aromatase inhibitors for the endocrine adjuvant treatment of breast cancer.
Topics: Anastrozole; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Enzyme Inhibitors; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2002 |
Estrogen as therapy for breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase II as Topic; Diethylstilbestrol; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Estrogens; Female; Humans; Letrozole; Megestrol Acetate; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Salvage Therapy; Tamoxifen; Treatment Outcome; Triazoles | 2002 |
Promising results for Arimidex and Femara.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials, Phase III as Topic; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2001 |
Stick with tried-and-true breast cancer treatment.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2002 |
New alternative to tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Nitriles; Triazoles | 2002 |
Biological activity of anastrozole in postmenopausal patients with advanced breast cancer: effects on estrogens and bone metabolism.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androgens; Biological Availability; Biomarkers; Biopsy, Needle; Breast Neoplasms; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Estrogens; Female; Humans; Middle Aged; Neoplasm Staging; Nitriles; Osteocalcin; Postmenopause; Prognosis; Prospective Studies; Sensitivity and Specificity; Sex Hormone-Binding Globulin; Treatment Outcome; Triazoles | 2002 |
Effective aromatase inhibition by anastrozole in a patient with gonadotropin-independent precocious puberty in McCune-Albright syndrome.
Topics: Anastrozole; Aromatase Inhibitors; Child; Enzyme Inhibitors; Estrogen Antagonists; Female; Fibrous Dysplasia, Polyostotic; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Menarche; Nitriles; Puberty, Precocious; Tamoxifen; Triazoles | 2002 |
Concept evaluation: an assay for receptor-mediated and biochemical antiestrogens using pubertal rats.
Topics: Administration, Oral; Anastrozole; Animals; Biological Assay; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Injections, Subcutaneous; Nitriles; Oligopeptides; Organ Size; Rats; Rats, Wistar; Sexual Maturation; Tetrahydronaphthalenes; Triazoles; Uterus; Vagina | 2002 |
Anastrozole versus tamoxifen as first-line therapy for advanced breast cancer: methodologic issues.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Randomized Controlled Trials as Topic; Research Design; Tamoxifen; Triazoles | 2002 |
Rapid determination of anastrozole in plasma by gas chromatography with electron capture detection and its application to an oral pharmacokinetic study in healthy volunteers.
Topics: Administration, Oral; Adult; Anastrozole; Area Under Curve; Aromatase Inhibitors; Chromatography, Gas; Cross-Over Studies; Enzyme Inhibitors; Half-Life; Humans; Male; Nitriles; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Triazoles | 2002 |
[Advanced breast cancer with lung and pleural metastases responsive to anastrozole--a case report].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Lung Neoplasms; Middle Aged; Nitriles; Pleural Effusion, Malignant; Pleural Neoplasms; Postmenopause; Receptors, Estrogen; Triazoles | 2002 |
The novel use of very high doses of cabergoline and a combination of testosterone and an aromatase inhibitor in the treatment of a giant prolactinoma.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Bromocriptine; Cabergoline; Dopamine Agonists; Enzyme Inhibitors; Ergolines; Hormone Replacement Therapy; Humans; Magnetic Resonance Imaging; Male; Nitriles; Pituitary Neoplasms; Prolactin; Prolactinoma; Sexual Dysfunction, Physiological; Testosterone; Treatment Outcome; Triazoles | 2002 |
[Campaign against breast cancer. Are aromatase inhibitors the better choice? (interview by Dr. Dorothea Dlugosch)].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Female; Humans; Nitriles; Tamoxifen; Treatment Outcome; Triazoles | 2002 |
Anastrozole versus progestins/tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Forecasting; Humans; Multicenter Studies as Topic; Nitriles; Progestins; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis; Tamoxifen; Triazoles | 2002 |
Selective oestrogen receptor downregulator.
Topics: Anastrozole; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Down-Regulation; Estradiol; Female; Fulvestrant; Humans; Nitriles; Receptors, Estrogen; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2002 |
From the Food and Drug Administration.
Topics: Adenine; Anastrozole; Antineoplastic Agents, Hormonal; Antiviral Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Hepatitis B, Chronic; Humans; Nitriles; Organophosphonates; Triazoles; United States; United States Food and Drug Administration | 2002 |
Invasive lobular carcinoma of the breast presenting successively with colonic and gastric metastases.
Topics: Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Colonic Neoplasms; Doxorubicin; Endoscopy; Female; Humans; Nitriles; Stomach Neoplasms; Tomography, X-Ray Computed; Treatment Outcome; Triazoles | 2002 |
Anastrozole is superior to tamoxifen as first-line therapy in hormone receptor-positive advanced breast carcinoma.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Multicenter Studies as Topic; Nitriles; Reproducibility of Results; Research Design; Retrospective Studies; Survival; Tamoxifen; Triazoles | 2002 |
Effects of anastrozole on lipid metabolism compared with tamoxifen in rats.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Cholesterol; Drug Combinations; Enzyme Inhibitors; Female; Lipoprotein Lipase; Nitriles; Rats; Tamoxifen; Triazoles; Triglycerides | 2002 |
Current role of endocrine therapy in the management of breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogen Receptor Modulators; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2002 |
Has tamoxifen had its day?
Topics: Anastrozole; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2002 |
A new day dawns: women without oestrogen or is a balance best?
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Estrogen Antagonists; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2002 |
Questions about anastrozole for early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Nitriles; Triazoles | 2002 |
Questions about anastrozole for early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Disease Progression; Female; Humans; Nitriles; Triazoles | 2002 |
Advances in breast oncology: the 2002 ASCO meeting.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclooxygenase Inhibitors; Docetaxel; Evidence-Based Medicine; Female; Humans; Nitriles; Paclitaxel; Sentinel Lymph Node Biopsy; Tamoxifen; Taxoids; Technology Assessment, Biomedical; Triazoles | 2002 |
New treatment option for postmenopausal women with early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Approval; Enzyme Inhibitors; Female; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2002 |
[A case of recurrent breast cancer with carcinomatous pleurisy successfully treated with combined chemoendocrine-therapy of CTF (CPA, THP and 5-FU) and anastrozole following instillation therapy 12 years after radical mastectomy].
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Medullary; Cyclophosphamide; Doxorubicin; Drainage; Drug Administration Schedule; Female; Fluorouracil; Humans; Lymphatic Metastasis; Mastectomy, Radical; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Pleural Effusion, Malignant; Pleurisy; Triazoles | 2002 |
[Summit meeting of breast cancer experts--many new ideas and practical progress. When the breast becomes malignant].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Mammography; Mass Screening; Nitriles; Quality Assurance, Health Care; Tamoxifen; Triazoles | 2003 |
Update on ATAC.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2003 |
Anastrozole (Arimidex) vs. tamoxifen for treatment of early breast cancer.
Topics: Anastrozole; Asthenia; Breast Neoplasms; Chemotherapy, Adjuvant; Dose-Response Relationship, Drug; Estrogen Antagonists; Fees, Pharmaceutical; Female; Headache; Humans; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2003 |
Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene.
Topics: Adipose Tissue; Adolescent; Adult; Anastrozole; Androstenedione; Aromatase; Aromatase Inhibitors; Base Sequence; Child; Chromosome Mapping; Chromosomes, Human, Pair 15; Dexamethasone; Enzyme Inhibitors; Estradiol; Estrone; Fibroblasts; Glucocorticoids; Gynecomastia; Humans; Male; Molecular Sequence Data; Mutation; Nitriles; Promoter Regions, Genetic; RNA, Messenger; Transcription, Genetic; Triazoles | 2003 |
Anastrozole-induced remission of diaphragmatic paralysis from metastatic breast cancer treated with multiple prior therapies.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Humans; Mediastinal Neoplasms; Middle Aged; Nitriles; Remission Induction; Respiratory Paralysis; Triazoles | 2003 |
Anastrozole as a preventive agent in breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Humans; Informed Consent; Nitriles; Postmenopause; Triazoles | 2003 |
Cost utility analysis of first-line hormonal therapy in advanced breast cancer: comparison of two aromatase inhibitors to tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Canada; Cost-Benefit Analysis; Decision Support Techniques; Enzyme Inhibitors; Humans; Letrozole; Meta-Analysis as Topic; Nitriles; Quality of Life; Tamoxifen; Triazoles | 2003 |
ATAC trial: reporting interim results is not helpful.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2003 |
Breast cancer prevention.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Utilization; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2003 |
[Hormone therapy, chemotherapy and immunotherapy in breast carcinoma. The best strategy for your patient].
Topics: Adult; Age Factors; Aged; Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Immunotherapy; Letrozole; Meta-Analysis as Topic; Middle Aged; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Nitriles; Premenopause; Prognosis; Quality of Health Care; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Toremifene; Trastuzumab; Triazoles | 2003 |
Economic evaluation of antiaromatase agents in the second-line treatment of metastatic breast cancer.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Canada; Clinical Trials, Phase III as Topic; Cost-Benefit Analysis; Enzyme Inhibitors; Female; Humans; Letrozole; Megestrol; Middle Aged; Nitriles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Survival Analysis; Triazoles | 2003 |
Examining quality of life issues in relation to endocrine therapy for breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Decision Making; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; Letrozole; Nitriles; Quality of Life; Tamoxifen; Triazoles | 2003 |
A new notocotylid trematode, Uniserialis gippyensis gen. et sp. nov., from the mallard, Anas platyrhyncha platyrhyncha L.
Topics: Anastrozole; Animals; Birds; Nitriles; Poultry; Trematoda; Triazoles | 1958 |
Imprinting and associative learning: the stability of the following response in Peking ducks (Anas platyrhynchus).
Topics: Anastrozole; Animals; Conditioning, Classical; Ducks; Humans; Learning; Nitriles; Triazoles | 1958 |
Anastrozole for ductal carcinoma in situ.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Attitude to Health; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Ductal, Breast; Female; Humans; Mass Screening; Nitriles; Triazoles | 2003 |
The comparative anatomy of the respiratory pathways in the domestic fowl (Gallus domesticus), pigeon (Columbia livia) and domestic duck (Anas platyrhyncha).
Topics: Anastrozole; Anatomy, Comparative; Animals; Chickens; Columbidae; Ducks; Nitriles; Poultry; Respiratory System; Triazoles | 1960 |
[On the female hybrid issuing from the crossbreeding of Cairina moschata L. (male) and Anas platvrhvnchos L. (female)].
Topics: Anastrozole; Animals; Ducks; Female; Hybridization, Genetic; Male; Nitriles; Triazoles | 1960 |
The effect of total and subtotal adrenalectomy on the renal and extra-renal response of the domestic duct (Anas platyrhynchus) to saline loading.
Topics: Adrenalectomy; Anastrozole; Kidney; Nitriles; Sodium Chloride; Triazoles | 1961 |
Doctors test drug to prevent cancer in high risk women.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Risk Factors; Triazoles | 2003 |
Future directions in the endocrine therapy of breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Endocrine System; Estradiol; Female; Fulvestrant; Humans; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles | 2003 |
Adjuvant aromatase inhibitors: are we there yet?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Triazoles | 2003 |
ATAC trial did not report interim results.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2003 |
The effects of hormone therapy on cognition in breast cancer.
Topics: Affect; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cognition; Cognition Disorders; Enzyme Inhibitors; Female; Humans; Memory; Middle Aged; Nitriles; Pilot Projects; Psychometrics; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2003 |
Hormonal therapy: introduction.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Letrozole; Nitriles; Prognosis; Risk Assessment; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles; United Kingdom | 2003 |
Cost-effectiveness of anastrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Health Care Costs; Health Services; Humans; Nitriles; Postmenopause; Quality-Adjusted Life Years; Tamoxifen; Triazoles | 2003 |
Spreading the word, but not too thinly.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Editorial Policies; Estradiol; Female; Fulvestrant; Humans; Nitriles; Patient Selection; Randomized Controlled Trials as Topic; Research Design; Retrospective Studies; Treatment Outcome; Triazoles | 2004 |
Data from the Arimidex, tamoxifen, alone or in combination (ATAC) trial: implications for use of aromatase inhibitors in 2003.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Time Factors; Triazoles | 2004 |
Prevention strategies with aromatase inhibitors.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Membrane Proteins; Models, Biological; Neoplasms; Nitriles; Placebos; Postmenopause; Prostaglandin-Endoperoxide Synthases; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles | 2004 |
Feasibility of sentinel node biopsy for breast cancer after neoadjuvant endocrine therapy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Anthracyclines; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Axilla; Breast Neoplasms; Bridged-Ring Compounds; Feasibility Studies; Female; Goserelin; Humans; Lymph Nodes; Middle Aged; Neoadjuvant Therapy; Nitriles; Pilot Projects; Sentinel Lymph Node Biopsy; Tamoxifen; Taxoids; Triazoles | 2004 |
Anas domestica as a definitive host and Ophicephalus argus as a second intermediate host of Clonorchis sinensis.
Topics: Anastrozole; Animals; Clonorchis sinensis; Ducks; Nitriles; Trematoda; Triazoles | 1951 |
Treatment of testosterone-induced gynecomastia with the aromatase inhibitor, anastrozole.
Topics: Adult; Anastrozole; Androgens; Aromatase Inhibitors; Enzyme Inhibitors; Gynecomastia; Humans; Hypogonadism; Male; Middle Aged; Nitriles; Testosterone; Triazoles | 2004 |
[New prevention strategies against breast cancer and cervical carcinoma. What can you advice to your patients].
Topics: Adolescent; Adult; Age Factors; Anastrozole; Anticarcinogenic Agents; Breast Neoplasms; Celecoxib; Child; Double-Blind Method; Estrogen Antagonists; Female; Germany; Hormone Replacement Therapy; Humans; Hysterectomy; Life Style; Mammography; Menarche; Menopause; Middle Aged; Nitriles; Ovariectomy; Pregnancy; Pyrazoles; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Smoking; Sulfonamides; Tamoxifen; Triazoles; Uterine Cervical Neoplasms | 2003 |
[Interview with Prof. Dr. Wolfgang Eiermann. Which women need a medicamentous breast cancer prophylaxis?].
Topics: Age Factors; Anastrozole; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Enzyme Inhibitors; Female; Humans; Life Style; Mammography; Middle Aged; Nitriles; Quality of Life; Risk Assessment; Risk Factors; Tamoxifen; Triazoles | 2003 |
[The uterine sarcoma, a new risk identified for tamoxifen].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinosarcoma; Enzyme Inhibitors; Estrogen Receptor Modulators; Female; Humans; Metrorrhagia; Middle Aged; Neoplasms, Second Primary; Nitriles; Risk; Tamoxifen; Triazoles; Uterine Neoplasms | 2004 |
Adjuvant use of anastrozole in breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Triazoles | 2004 |
Comment on "Anastrozole (Arimidex) versus tamoxifen as first-line therapy for advanced breast cancer in postmenopausal women: survival analysis and updated safety results" by J.-M. Nabholtz et al.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Letrozole; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Triazoles | 2004 |
Effect of estrogen deprivation on follicle/oocyte maturation and embryo development in mice.
Topics: Anastrozole; Animals; Chorionic Gonadotropin; Embryonic and Fetal Development; Estrogens; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nitriles; Oocytes; Ovarian Follicle; Pregnancy; Triazoles | 2004 |
Successful treatment of severe endometriosis in two premenopausal women with an aromatase inhibitor.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Drug Therapy, Combination; Endometriosis; Enzyme Inhibitors; Female; Humans; Nitriles; Progesterone; Triazoles | 2004 |
Comparison of two aromatase inhibitors in women with clomiphene-resistant polycystic ovary syndrome.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Clomiphene; Estrogen Antagonists; Female; Humans; Letrozole; Nitriles; Ovulation; Ovulation Induction; Polycystic Ovary Syndrome; Pregnancy; Triazoles | 2004 |
Dynamic contrast enhanced magnetic resonance imaging in monitoring bone metastases in breast cancer patients receiving bisphosphonates and endocrine therapy.
Topics: Adult; Aged; Anastrozole; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Female; Goserelin; Humans; Imidazoles; Letrozole; Magnetic Resonance Imaging; Middle Aged; Nitriles; Pamidronate; Pilot Projects; Prospective Studies; Tamoxifen; Triazoles; Zoledronic Acid | 2004 |
An open randomised trial of second-line endocrine therapy in advanced breast cancer: comparison of the Aromatase inhibitors letrozole and anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 2004 |
Recurrence of prolactin-producing endometrial stromal sarcoma with sex-cord stromal component treated with progestin and aromatase inhibitor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Endometrial Neoplasms; Enzyme Inhibitors; Female; Humans; Megestrol Acetate; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Progestins; Prolactin; Sarcoma, Endometrial Stromal; Triazoles | 2004 |
Anastrozole, an aromatase inhibitor, and medroxyprogesterone acetate therapy in premenopausal obese women with endometrial cancer: a report of two cases successfully treated without hysterectomy.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Medroxyprogesterone Acetate; Nitriles; Obesity; Triazoles | 2004 |
[Ulcus terebrans. Therapy options and their limits].
Topics: Aged; Anastrozole; Breast Neoplasms; Carcinoma, Basal Cell; Carcinoma, Ductal, Breast; Combined Modality Therapy; Debridement; Female; Humans; Incidental Findings; Neoplasm Staging; Neoplasms, Multiple Primary; Nitriles; Palliative Care; Radioisotope Teletherapy; Scalp; Skin Neoplasms; Skin Ulcer; Triazoles | 2004 |
Benefit and projected cost-effectiveness of anastrozole versus tamoxifen as initial adjuvant therapy for patients with early-stage estrogen receptor-positive breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Middle Aged; Models, Theoretical; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
[Therapeutic effects of Anastrozole in patients with advanced and recurrent breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cholesterol; Drug Administration Schedule; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Salvage Therapy; Survival Rate; Triazoles | 2004 |
[Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer].
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Administration Schedule; Female; Floxuridine; Humans; Lymphatic Metastasis; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Survival Rate; Triazoles | 2004 |
Quality of life of postmenopausal women in the Arimidex, Tamoxifen, Alone or in Combination (ATAC) Adjuvant Breast Cancer Trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Odds Ratio; Postmenopause; Quality of Life; Surveys and Questionnaires; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2004 |
Cost utility and budget impact of third-generation aromatase inhibitors for advanced breast cancer: a literature-based model analysis of costs in the Italian National Health Service.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Budgets; Cost-Benefit Analysis; Decision Support Techniques; Drug Costs; Female; Humans; Italy; Letrozole; Markov Chains; Megestrol; Models, Economic; National Health Programs; Nitriles; Postmenopause; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2004 |
[Anastrozole-resistant breast cancer responsive to exemestane--a case report].
Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Resistance, Neoplasm; Female; Humans; Nitriles; Postmenopause; Triazoles | 2004 |
The responsiveness of a tumour to any kind of therapy is reflected by the objective response rate.
Topics: Anastrozole; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Triazoles | 2004 |
Arimidex inhibition on proliferation of human breast solid tumors measured by ATP bioluminescence.
Topics: Adenosine Triphosphatases; Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Proliferation; Female; Humans; Luminescent Measurements; Luminescent Proteins; Middle Aged; Nitriles; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Triazoles; Tumor Cells, Cultured | 2004 |
Oestrogen-selective modulation of FSH and LH secretion by pituitary gland.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estrogens; Female; Follicle Stimulating Hormone; Goserelin; Humans; Luteinizing Hormone; Nitriles; Pituitary Gland; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2005 |
Osteoprotegerin and osteopontin serum values in postmenopausal advanced breast cancer patients treated with anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Female; Glycoproteins; Humans; Middle Aged; Nitriles; Osteopontin; Osteoprotegerin; Postmenopause; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Sialoglycoproteins; Survival Analysis; Triazoles | 2004 |
How rapidly do oncologists respond to clinical trial data?
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Evidence-Based Medicine; Female; Health Care Surveys; Humans; Medical Oncology; Middle Aged; Nitriles; Postmenopause; Practice Patterns, Physicians'; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2005 |
An open label 12-month pilot trial on the effects of the aromatase inhibitor anastrozole in growth hormone (GH)-treated GH deficient adolescent boys.
Topics: Absorptiometry, Photon; Adolescent; Anastrozole; Aromatase Inhibitors; Blood Glucose; Body Composition; Bone Density; Growth Hormone; Humans; Insulin; Male; Nitriles; Pilot Projects; Triazoles | 2004 |
Anastrozole data show continued delay in relapse, but no clear survival advantage.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cost-Benefit Analysis; Disease-Free Survival; Drug Costs; Female; Humans; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles; United Kingdom | 2005 |
Expression of estrogen receptors-alpha and -beta in primary breast neoplasms and tumors exposed to neoadjuvant hormonal therapy.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Gene Expression Regulation, Neoplastic; Humans; Nitriles; Receptors, Progesterone; RNA, Messenger; Tamoxifen; Triazoles | 2004 |
[Weekly paclitaxel administration and intraabdominal CBDCA injection possibly beneficial treatment for recurrent breast cancer associated with metastatic ovarian cancer and peritoneal dissemination after operation--a case report].
Topics: Adenocarcinoma, Scirrhous; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Drug Administration Schedule; Female; Floxuridine; Humans; Hysterotomy; Infusions, Intravenous; Injections, Intraperitoneal; Middle Aged; Nitriles; Ovarian Neoplasms; Paclitaxel; Peritoneal Neoplasms; Triazoles | 2005 |
[Breast carcinoma: new, much promising trends. The cancer anxiety of women -- will be taken better care soon?].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Austria; Breast Neoplasms; Clinical Trials as Topic; Female; Fractures, Bone; Germany; Humans; Mammography; Middle Aged; Multicenter Studies as Topic; Nitriles; Osteoporosis; Randomized Controlled Trials as Topic; Risk; Risk Factors; Tamoxifen; Time Factors; Triazoles | 2005 |
[New strategies against breast carcinoma. To outwit the resistance tendency of tumor cells].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Time Factors; Triazoles | 2005 |
Letrozole-, anastrozole-, and tamoxifen-responsive genes in MCF-7aro cells: a microarray approach.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Cell Line, Tumor; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Nitriles; Oligonucleotide Array Sequence Analysis; Tamoxifen; Triazoles; Up-Regulation | 2005 |
Remission of macroglobulinemia during anastrozole treatment for breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Nitriles; Remission Induction; Triazoles; Waldenstrom Macroglobulinemia | 2005 |
[Three cases of advanced breast cancer successfully treated with a weekly dose of paclitaxel].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Mastectomy, Modified Radical; Middle Aged; Neoplasm Invasiveness; Nitriles; Paclitaxel; Skin Neoplasms; Sternum; Triazoles | 2005 |
Novel males' capacity to disrupt early pregnancy in mice (Mus musculus) is attenuated via a chronic reduction of males' urinary 17beta-estradiol.
Topics: Anastrozole; Animals; Aromatase; Diet; Embryo Implantation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Fertility; Insemination; Male; Mice; Nitriles; Phytoestrogens; Pregnancy; Pregnancy, Animal; Social Isolation; Testosterone; Triazoles | 2005 |
Current and future perspectives on fulvestrant.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Estradiol; Female; Fulvestrant; Humans; Nitriles; Receptors, Estrogen; Triazoles | 2005 |
Alternative to tamoxifen effective for preventing breast cancer recurrence.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Triazoles | 2005 |
Regression of choroidal metastases from breast carcinoma using aromatase inhibitors.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Choroid Neoplasms; Female; Humans; Nitriles; Triazoles | 2005 |
The aromatase inhibitor anastrozole is associated with favorable embryo development and implantation markers in mice ovarian stimulation cycles.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Biomarkers; Embryonic Development; Estrous Cycle; Female; Male; Mice; Nitriles; Ovulation Induction; Triazoles | 2005 |
Selected highlights from the 27th San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 8-11 December 2004.
Topics: Anastrozole; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Delivery Systems; Drug Therapy, Combination; Estradiol; Female; Fulvestrant; Gonadal Steroid Hormones; Humans; Neoadjuvant Therapy; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Tamoxifen; Taxoids; Trastuzumab; Triazoles | 2005 |
Aromatase inhibitors: cellular and molecular effects.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Female; Gene Expression; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Nitriles; Oligonucleotide Array Sequence Analysis; Receptors, Progesterone; Tamoxifen; Triazoles | 2005 |
Sperm analysis in growth hormone-deficient adolescents previously treated with an aromatase inhibitor: comparison with normal controls.
Topics: Adolescent; Adult; Anastrozole; Aromatase Inhibitors; Cohort Studies; Human Growth Hormone; Humans; Male; Nitriles; Reference Standards; Reference Values; Sperm Count; Spermatozoa; Triazoles | 2005 |
Effects of anastrozole on the intratumoral gene expression in locally advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression; Humans; Nitriles; Oligonucleotide Array Sequence Analysis; Triazoles | 2005 |
Case records of the Massachusetts General Hospital. Case 24-2005. A 58-year-old woman with early-stage estrogen-receptor-positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Diagnosis, Differential; Female; Humans; Mammography; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Nitriles; Radiotherapy, Adjuvant; Receptors, Estrogen; Sentinel Lymph Node Biopsy; Tamoxifen; Triazoles | 2005 |
Radiotherapeutic prophylaxis of gynecomastia.
Topics: Anastrozole; Androgen Antagonists; Anilides; Antineoplastic Agents, Hormonal; Gynecomastia; Humans; Male; Nitriles; Pain; Prostatic Neoplasms; Quality of Life; Tamoxifen; Tosyl Compounds; Triazoles | 2005 |
Promising switch to anastrozole for breast-cancer treatment.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Nitriles; Triazoles | 2005 |
[Neoadjuvant endocrine therapy with anastrozole significantly downstaged an elderly breast cancer woman with locally-advanced breast cancer which became operable].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Neoadjuvant Therapy; Nitriles; Postmenopause; Preoperative Care; Sternum; Triazoles | 2005 |
[Aromatase inhibitors in the treatment of breast cancer: current status and some problems].
Topics: Adult; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Triazoles | 2005 |
A step too far?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Approval; Female; Humans; Nitriles; Scotland; Triazoles; United Kingdom | 2005 |
Role of the vaginally administered aromatase inhibitor anastrozole in women with rectovaginal endometriosis: a pilot study.
Topics: Administration, Intravaginal; Adult; Anastrozole; Aromatase Inhibitors; Chi-Square Distribution; Endometriosis; Female; Humans; Nitriles; Pilot Projects; Rectal Diseases; Triazoles; Vaginal Diseases | 2005 |
Regression of tamoxifen-stimulated massive uterine fibroid after conversion to anastrozole.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Female; Humans; Leiomyoma; Nitriles; Remission Induction; Retreatment; Tamoxifen; Triazoles; Ultrasonography; Uterine Neoplasms | 2005 |
Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Endometrial Neoplasms; Estradiol; Female; Fulvestrant; Humans; Lung Neoplasms; Nitriles; Progestins; Triazoles | 2006 |
Growth inhibition of estrogen receptor-positive and aromatase-positive human breast cancer cells in monolayer and spheroid cultures by letrozole, anastrozole, and tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Estrogen Antagonists; Humans; Inhibitory Concentration 50; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles | 2005 |
Case 24-2005: a woman with estrogen-receptor-positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Diseases, Metabolic; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fractures, Bone; Humans; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles | 2005 |
Lobular carcinoma of the breast metastatic to the uterus in a patient under adjuvant anastrozole therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Endometrial Neoplasms; Female; Humans; Hysterectomy; Immunohistochemistry; Keratins; Mastectomy, Modified Radical; Middle Aged; Mucin-1; Nitriles; Ovariectomy; Triazoles; Ultrasonography; Vagina | 2006 |
Anal localization as first manifestation of metastatic ductal breast carcinoma.
Topics: Aged; Anastrozole; Anus Neoplasms; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Colectomy; Female; Follow-Up Studies; Humans; Immunohistochemistry; Neoplasm Staging; Nitriles; Rare Diseases; Risk Assessment; Treatment Outcome; Triazoles | 2005 |
Aromatase inhibitors in human lung cancer therapy.
Topics: Anastrozole; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Carcinoma, Non-Small-Cell Lung; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoblotting; Immunoenzyme Techniques; Lung Neoplasms; Male; Mice; Mice, Nude; Nitriles; Ovariectomy; Reverse Transcriptase Polymerase Chain Reaction; Transplantation, Heterologous; Triazoles | 2005 |
Treatment guidelines for adjuvant breast cancer are moving toward double standards: one for the rich and one for the poor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Decision Making; Developing Countries; Disease-Free Survival; Drug Costs; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2005 |
Regulation of sexual behaviour in male macaques by sex steroid modulation of the serotonergic system.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Autonomic Nervous System; Estradiol; Female; Gonadal Steroid Hormones; Macaca; Male; Nitriles; Oligopeptides; Reaction Time; Serotonin; Sexual Behavior, Animal; Triazoles; Tryptophan | 2006 |
Influence of adjuvant anastrozole on bone mineral density in Japanese postmenopausal breast cancer patients: is there a racial difference?
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Asian People; Biomarkers; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Japan; Middle Aged; Nitriles; Postmenopause; Triazoles; White People | 2006 |
Sequential treatment with exemestane and non-steroidal aromatase inhibitors in advanced breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Confidence Intervals; Disease Progression; Drug Administration Schedule; Female; Humans; Letrozole; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2005 |
Improvement in dermatomyositis rash associated with the use of antiestrogen medication.
Topics: Adult; Anastrozole; Biopsy; Breast Neoplasms; Dermatomyositis; Diagnosis, Differential; Estrogen Antagonists; Exanthema; Female; Follow-Up Studies; Glucocorticoids; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Skin; Tamoxifen; Triazoles | 2006 |
Anastrozole called breast cancer "lifesaver". Recipients showed a 40 percent decrease in relapse risk when switched to anastrazole after tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Triazoles | 2005 |
Latest studies hint at survival advantage with aromatase inhibitors in early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Europe; Female; Humans; Letrozole; Meta-Analysis as Topic; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Survival Analysis; Survival Rate; Treatment Outcome; Triazoles | 2006 |
Effects of decreased estradiol-17beta on the serum and anterior pituitary IGF-I system in pigs.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Blotting, Western; Estradiol; Female; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor I; Male; Nitriles; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Swine; Testosterone; Triazoles | 2005 |
Prepubertal gynecomastia in Peutz-Jeghers syndrome: incomplete penetrance in a familial case and management with an aromatase inhibitor.
Topics: Anastrozole; Anti-Mullerian Hormone; Aromatase Inhibitors; Child; DNA; Female; Glycoproteins; Gynecomastia; Humans; Inhibins; Longitudinal Studies; Male; Nitriles; Pedigree; Penetrance; Peutz-Jeghers Syndrome; Sequence Analysis, DNA; Sertoli Cell Tumor; Testicular Hormones; Triazoles | 2006 |
Photodynamic therapy for solitary retinal metastasis from breast carcinoma.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Middle Aged; Nitriles; Photochemotherapy; Retinal Neoplasms; Triazoles | 2006 |
[Advance and current status of exemestane and androstadienes in the treatment of breast cancer].
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Female; Humans; Nitriles; Postmenopause; Triazoles | 2005 |
Changing the gold standard in adjuvant therapy for breast cancer:from tamoxifen to aromatase inhibition.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Enzyme Inhibitors; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2005 |
Does survival increase in metastatic breast cancer with recently available anticancer drugs?
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Retrospective Studies; Survival Analysis; Tamoxifen; Triazoles | 2006 |
Anastrozole is cost-effective vs tamoxifen as initial adjuvant therapy in early breast cancer: Canadian perspectives on the ATAC completed-treatment analysis.
Topics: Analysis of Variance; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Risk Reduction Behavior; Sensitivity and Specificity; Survival Rate; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2006 |
[Advances in the treatment of breast carcinoma. New therapy schedules with astonishing success quotas].
Topics: Age Factors; Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Aromatase Inhibitors; Breast Neoplasms; Docetaxel; Female; Humans; Mammography; Meta-Analysis as Topic; Middle Aged; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Risk; Tamoxifen; Taxoids; Time Factors; Trastuzumab; Triazoles | 2006 |
Plasma levels of tamoxifen, N-desmethyl tamoxifen and anastrozole in a patient with metastatic breast cancer and chronic hemodialysis.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Renal Dialysis; Tamoxifen; Triazoles | 2006 |
Identification of the aromatase inhibitors anastrozole and exemestane in human urine using liquid chromatography/tandem mass spectrometry.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chromatography, High Pressure Liquid; Female; Humans; Male; Nitriles; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Substance Abuse Detection; Tandem Mass Spectrometry; Triazoles | 2006 |
Adjuvant aromatase inhibitors for early breast cancer after chemotherapy-induced amenorrhoea: caution and suggested guidelines.
Topics: Adult; Amenorrhea; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Receptor Modulators; Female; Follicle Stimulating Hormone; Humans; Letrozole; Luteinizing Hormone; Middle Aged; Neoplasm Staging; Nitriles; Ovariectomy; Practice Guidelines as Topic; Tamoxifen; Triazoles | 2006 |
Pharmacoeconomic analysis of adjuvant therapy with exemestane, anastrozole, letrozole or tamoxifen in postmenopausal women with operable and estrogen receptor-positive breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cohort Studies; Computer Simulation; Cost-Benefit Analysis; Estrogen Antagonists; Estrogens; Fees, Pharmaceutical; Female; Follow-Up Studies; Humans; Letrozole; Markov Chains; Middle Aged; Models, Theoretical; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Receptors, Estrogen; Tamoxifen; Triazoles | 2006 |
Primary hormone treatment in postmenopausal women with breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Contraindications; Estrogens; Female; Humans; Letrozole; Mastectomy; Neoadjuvant Therapy; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Radiography; Receptors, Estrogen; Triazoles | 2006 |
Estrogen receptors: role in breast cancer.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Gene Expression Regulation, Neoplastic; Gonadotropin-Releasing Hormone; Hormone Replacement Therapy; Humans; Letrozole; Models, Biological; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2006 |
Management of choroidal metastases from breast carcinomas using aromatase inhibitors.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Choroid Neoplasms; Combined Modality Therapy; Female; Humans; Letrozole; Mastectomy, Radical; Mastectomy, Segmental; Mastectomy, Simple; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
Impact of chemotherapy regimens prior to endocrine therapy: Results from the ATAC (Anastrozole and Tamoxifen, Alone or in Combination) trial.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Recurrence; Retrospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
Leuprolide acetate plus aromatase inhibition for male breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms, Male; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Humans; Letrozole; Leuprolide; Lung Neoplasms; Lymphatic Metastasis; Male; Mastectomy, Modified Radical; Middle Aged; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Treatment Outcome; Triazoles | 2006 |
Anastrozole therapy in recurrent ovarian adult granulosa cell tumors: a report of 2 cases.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Female; Granulosa Cell Tumor; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Ovarian Neoplasms; Triazoles | 2006 |
Cost-utility of adjuvant hormone therapies for breast cancer in post-menopausal women: sequential tamoxifen-exemestane and upfront anastrozole.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Drug Administration Schedule; Drug Costs; Female; Humans; Markov Chains; Middle Aged; Models, Economic; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Quality-Adjusted Life Years; Tamoxifen; Treatment Outcome; Triazoles; United States | 2007 |
Pharmacoeconomic aspects of adjuvant anastrozole or tamoxifen in breast cancer: a Slovenian perspective.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Cost-Benefit Analysis; Decision Trees; Disease-Free Survival; Economics, Pharmaceutical; Humans; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Slovenia; Tamoxifen; Treatment Outcome; Triazoles | 2006 |
Joint symptoms: a practical problem of anastrozole.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Interviews as Topic; Joint Diseases; Middle Aged; Nitriles; Postmenopause; Triazoles | 2006 |
[Unclear about anastrozole and cancer treatment].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Drug Prescriptions; Humans; Nitriles; Norway; Reimbursement Mechanisms; Triazoles | 2006 |
Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Child; Child, Preschool; Humans; Male; Mutation; Nitriles; Puberty, Precocious; Receptors, LH; Tosyl Compounds; Triazoles | 2006 |
Combined ovarian ablation and aromatase inhibition as first-line therapy for hormone receptor-positive metastatic breast cancer in premenopausal women: report of three cases.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoplasm Metastasis; Neoplasms, Hormone-Dependent; Nitriles; Ovariectomy; Ovary; Premenopause; Receptors, Steroid; Triazoles | 2006 |
Cost-effectiveness of anastrozole compared to tamoxifen in hormone receptor-positive early breast cancer. Analysis based on the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Disease-Free Survival; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Quality-Adjusted Life Years; Receptors, Estrogen; Receptors, Progesterone; Sensitivity and Specificity; Survival Rate; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2006 |
Anastrozole improved testosterone-induced impairment acquisition of spatial learning and memory in the hippocampal CA1 region in adult male rats.
Topics: Analysis of Variance; Anastrozole; Animals; Aromatase Inhibitors; Discrimination Learning; Escape Reaction; Estradiol; Hippocampus; Male; Maze Learning; Memory Disorders; Microinjections; Nitriles; Rats; Rats, Wistar; Reaction Time; Spatial Behavior; Statistics, Nonparametric; Testosterone; Triazoles | 2006 |
Formulation of anastrozole microparticles as biodegradable anticancer drug carriers.
Topics: Anastrozole; Antineoplastic Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Lactic Acid; Nitriles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Triazoles | 2006 |
Anastrozole-induced hepatotoxicity.
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Lobular; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Diseases; Liver Function Tests; Nausea; Nitriles; Triazoles | 2006 |
Aromatase inhibitors and bipolar mood disorder: a case report.
Topics: Aggression; Anastrozole; Aromatase Inhibitors; Bipolar Disorder; Breast Neoplasms; Carcinoma, Lobular; Chemotherapy, Adjuvant; Combined Modality Therapy; Depressive Disorder, Major; Female; Humans; Irritable Mood; Letrozole; Middle Aged; Nitriles; Substance Withdrawal Syndrome; Triazoles | 2006 |
Henoch-Schönlein purpura (HSP) during treatment with anastrozole.
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; IgA Vasculitis; Nitriles; Triazoles | 2007 |
Modeling for cost-effective-adjuvant aromatase inhibitor strategies for postmenopausal women with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cost of Illness; Cost-Benefit Analysis; Drug Costs; Female; Humans; Markov Chains; Middle Aged; Models, Economic; Nitriles; Postmenopause; Quality of Life; Quality-Adjusted Life Years; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Clinically occult cutaneous metastases.
Topics: Aged; Aged, 80 and over; Anastrozole; Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Capecitabine; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Lobular; Carcinoma, Signet Ring Cell; Deoxycytidine; Estradiol; Facial Neoplasms; Female; Fluorouracil; Fulvestrant; Humans; Incidental Findings; Letrozole; Mastectomy, Radical; Megestrol Acetate; Melanoma; Neoplasms, Second Primary; Neoplastic Cells, Circulating; Nitriles; Selective Estrogen Receptor Modulators; Skin Neoplasms; Tamoxifen; Triazoles; Wound Healing | 2006 |
Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Cell Survival; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Drug Resistance; Estrogens; Female; Male; Nerve Degeneration; Neural Pathways; Neuronal Plasticity; Neurotoxins; Nitriles; Oxidopamine; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Sex Characteristics; Substantia Nigra; Triazoles | 2007 |
Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Gefitinib; Humans; Isoenzymes; Lymphatic Metastasis; Middle Aged; Nitriles; Quinazolines; Triazoles | 2006 |
Impact of aromatase inhibitors on adhesion formation in a rat model.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Cytokines; Disease Models, Animal; Female; Medroxyprogesterone Acetate; Nitriles; Postoperative Complications; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Tissue Adhesions; Triazoles; Uterine Diseases; Uterus | 2007 |
Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Belgium; Breast Neoplasms; Canada; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Drug Costs; Female; Humans; Letrozole; Markov Chains; Middle Aged; Nitriles; Postmenopause; Proportional Hazards Models; Quality-Adjusted Life Years; Tamoxifen; Triazoles | 2007 |
Severe acute hepatitis in a patient treated with anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Chemical and Drug Induced Liver Injury; Fatal Outcome; Female; Humans; Middle Aged; Nitriles; Triazoles | 2007 |
[Two patients having recurrent breast cancer with brain metastases well controlled with a gamma knife radio-surgery].
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Female; Hepatectomy; Humans; Infusions, Intra-Arterial; Liver Neoplasms; Mastectomy; Middle Aged; Nitriles; Paclitaxel; Pleurisy; Pleurodesis; Radiosurgery; Triazoles | 2006 |
[Locally advanced breast cancer with a good response to sequential endocrine monotherapy--a case report].
Topics: Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Drug Administration Schedule; Female; Humans; Nitriles; Remission Induction; Tamoxifen; Triazoles | 2007 |
Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer.
Topics: Adult; Aged; Analysis of Variance; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Follow-Up Studies; Humans; Ki-67 Antigen; Middle Aged; Multivariate Analysis; Neoadjuvant Therapy; Neoplasms, Hormone-Dependent; Nitriles; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Receptors, Estrogen; Sample Size; Tamoxifen; Triazoles | 2007 |
Anastrozole quantification in human plasma by high-performance liquid chromatography coupled to photospray tandem mass spectrometry applied to pharmacokinetic studies.
Topics: Anastrozole; Aromatase Inhibitors; Calibration; Chromatography, High Pressure Liquid; Humans; Nitriles; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazoles | 2007 |
Cost-effectiveness analysis of anastrozole versus tamoxifen as primary adjuvant therapy for postmenopausal women with early breast cancer: a US healthcare system perspective. The 5-year completed treatment analysis of the ATAC ('Arimidex', Tamoxifen Alone
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Drug Costs; Female; Health Services Research; Humans; Markov Chains; Middle Aged; Nitriles; Postmenopause; Quality-Adjusted Life Years; Tamoxifen; Triazoles; United Kingdom; United States | 2007 |
Differential effects of tamoxifen and anastrozole on optic cup size in breast cancer survivors.
Topics: Adult; Aged; Amenorrhea; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Female; Humans; Lasers; Middle Aged; Nitriles; Ophthalmoscopy; Optic Disk; Selective Estrogen Receptor Modulators; Survival Rate; Survivors; Tamoxifen; Triazoles; Visual Acuity | 2007 |
Potential benefit of maintenance trastuzumab and anastrozole therapy in male advanced breast cancer.
Topics: Adult; Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms, Male; Humans; Male; Nitriles; Receptor, ErbB-2; Receptors, Estrogen; Trastuzumab; Triazoles | 2007 |
t(8;16) AML developed subsequent to breast cancer therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Doxorubicin; Estrogens; Fatal Outcome; Female; Fluorouracil; Humans; Idarubicin; Leukemia, Myelomonocytic, Acute; Mastectomy, Modified Radical; Middle Aged; Neoplasms, Hormone-Dependent; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Nitriles; Radiotherapy, Adjuvant; Translocation, Genetic; Triazoles | 2006 |
Unusual macular degeneration following breast cancer.
Topics: Adenocarcinoma; Anastrozole; Aromatase Inhibitors; Bone Neoplasms; Breast Neoplasms; Choroid Neoplasms; Female; Humans; Lymphatic Metastasis; Macular Degeneration; Mastectomy, Radical; Middle Aged; Nitriles; Technetium; Tomography, X-Ray Computed; Triazoles | 2007 |
[A case of advanced breast cancer with multiple liver metastases resistant to chemotherapy responding to high-dose toremifene].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Liver Neoplasms; Middle Aged; Nitriles; Quality of Life; Remission Induction; Toremifene; Triazoles | 2007 |
A case of porphyria cutanea tarda resulting in digital amputation and improved by anastrazole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Fingers; Hand Dermatoses; Humans; Lymphoma, B-Cell; Middle Aged; Nitriles; Porphyria Cutanea Tarda; Treatment Outcome; Triazoles | 2007 |
[Clinical study of aromatase inhibitors in advanced breast cancer].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2007 |
Patients' knowledge and experience of adjuvant endocrine therapy for early breast cancer: a European study.
Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Communication Barriers; Decision Making; Europe; Female; Health Knowledge, Attitudes, Practice; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Selective Estrogen Receptor Modulators; Surveys and Questionnaires; Tamoxifen; Triazoles | 2007 |
Clinical evaluation of the use of exemestane as further hormonal therapy after nonsteroidal aromatase inhibitors in postmenopausal metastatic breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2007 |
Parotid gland metastasis of a breast cancer.
Topics: Anastrozole; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Capecitabine; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Deoxycytidine; Doxorubicin; Female; Fluorouracil; Humans; Immunohistochemistry; Mastectomy, Radical; Middle Aged; Nitriles; Parotid Gland; Parotid Neoplasms; Receptors, Estrogen; Time Factors; Treatment Outcome; Triazoles | 2007 |
Assessing the risk of bone fracture among postmenopausal women who are receiving adjuvant hormonal therapy for breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colles' Fracture; Female; Fractures, Bone; Humans; Middle Aged; Nitriles; Postmenopause; Risk Assessment; Tamoxifen; Triazoles; Wrist Injuries | 2007 |
Optimal use of aromatase inhibitors: to lead or to follow?
Topics: Aged; Alleles; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Recurrence; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Bone density in breast cancer: when to intervene?
Topics: Absorptiometry, Photon; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Diphosphonates; Female; Fractures, Bone; Goserelin; Humans; Imidazoles; Nitriles; Osteoporosis; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles; Zoledronic Acid | 2007 |
Cost utility analysis of early adjuvant letrozole or anastrozole versus tamoxifen in postmenopausal women with early invasive breast cancer: the UK perspective.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cost-Benefit Analysis; Female; Humans; Letrozole; Markov Chains; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Quality of Life; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles; United Kingdom | 2008 |
Nanomolar concentrations of anabolic-androgenic steroids amplify excitotoxic neuronal death in mixed mouse cortical cultures.
Topics: Anastrozole; Androgen Antagonists; Androgens; Animals; Aromatase Inhibitors; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Agonists; Female; Flutamide; L-Lactate Dehydrogenase; Mice; N-Methylaspartate; Neuroglia; Neurons; Nitriles; Pregnancy; Testosterone; Triazoles | 2007 |
Metastatic uterine leiomyosarcoma regression using an aromatase inhibitor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Combined Modality Therapy; Female; Humans; Hysterectomy; Immunohistochemistry; Leiomyosarcoma; Lung Neoplasms; Middle Aged; Nitriles; Remission Induction; Treatment Outcome; Triazoles; Uterine Neoplasms | 2007 |
Enhancement of the antitumor activity of tamoxifen and anastrozole by the farnesyltransferase inhibitor lonafarnib (SCH66336).
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Apoptosis; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Drug Synergism; Enzyme Inhibitors; Farnesyltranstransferase; Female; G1 Phase; Humans; In Situ Nick-End Labeling; Mice; Mice, Nude; Neoplasm Transplantation; Nitriles; Ovariectomy; Piperidines; Pyridines; S Phase; Tamoxifen; Triazoles | 2007 |
Severe disabling tendinopathy caused by anastrazole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Female; Humans; Middle Aged; Nitriles; Tendinopathy; Triazoles; Wrist Joint | 2007 |
Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
Topics: Anastrozole; Aromatase Inhibitors; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Nitriles; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Sulfatases; Triazoles | 2007 |
Aromatase inhibitor-induced bone mineral loss and its prevention by bisphosphonate administration in postmenopausal breast cancer patients.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Drug Interactions; Etidronic Acid; Female; Humans; Middle Aged; Nitriles; Osteoporosis; Postmenopause; Risedronic Acid; Triazoles | 2007 |
Aromatase inhibitor-associated arthralgias: Pathogenesis, frequency and management.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 2007 |
Joint pain with aromatase inhibitors: abnormal frequency of Sjögren's syndrome.
Topics: Aged; Anastrozole; Antibodies, Antinuclear; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Nitriles; Sjogren's Syndrome; Tamoxifen; Triazoles | 2007 |
Effects of aromatase inhibitors letrozole and anastrazole on bone metabolism and steroid hormone levels in intact female rats.
Topics: Amino Acids; Anastrozole; Animals; Aromatase Inhibitors; Bone Density; Dehydroepiandrosterone Sulfate; Dose-Response Relationship, Drug; Female; Letrozole; Nitriles; Osteocalcin; Rats; Testosterone; Triazoles | 2007 |
Responses to concurrent radiotherapy and hormone-therapy and outcome for large breast cancers in post-menopausal women.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Combined Modality Therapy; Estrogen Antagonists; Female; Humans; Middle Aged; Nitriles; Postmenopause; Radiotherapy Dosage; Retrospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Dual aromatase-sulfatase inhibitors based on the anastrozole template: synthesis, in vitro SAR, molecular modelling and in vivo activity.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Molecular Conformation; Nitriles; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfatases; Triazoles | 2007 |
Resolution of endometrial hyperplasia with adjuvant anastrozole treatment in postmenopausal breast cancer: a case report.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Endometrial Hyperplasia; Female; Humans; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles; Uterine Hemorrhage | 2007 |
Efficacy of anastrozole on local recurrence in patients with favorable early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Mastectomy, Segmental; Neoplasm Recurrence, Local; Nitriles; Tamoxifen; Triazoles | 2007 |
New 7,8-benzoflavanones as potent aromatase inhibitors: synthesis and biological evaluation.
Topics: Anastrozole; Aromatase Inhibitors; Benzene; Cyclization; Flavanones; Humans; Hydrogen Bonding; Letrozole; Microsomes; Molecular Structure; Nitriles; Structure-Activity Relationship; Triazoles | 2008 |
[Solitary oesophageal metastasis of breast cancer after 17 years latency].
Topics: Adenocarcinoma; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Chemotherapy, Adjuvant; Deglutition; Esophageal Neoplasms; Esophagus; Fatal Outcome; Female; Humans; Intubation; Middle Aged; Minimally Invasive Surgical Procedures; Nitriles; Palliative Care; Radiotherapy, Adjuvant; Thoracotomy; Tomography, X-Ray Computed; Treatment Outcome; Triazoles | 2007 |
Anastrozole-induced subacute cutaneous lupus erythematosus.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Female; Humans; Lupus Erythematosus, Cutaneous; Nitriles; Treatment Outcome; Triazoles | 2008 |
Endocrine and targeted manipulation of breast cancer: summary statement for the Sixth Cambridge Conference.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Triazoles | 2008 |
Extended adjuvant therapy for breast cancer--how much is enough?
Topics: Aminoglutethimide; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Austria; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Tamoxifen; Treatment Outcome; Triazoles | 2007 |
Long-term outcomes of aromatase inhibition for breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Female; Follow-Up Studies; Fractures, Bone; Humans; Nitriles; Postmenopause; Survival Analysis; Tamoxifen; Time Factors; Triazoles | 2008 |
The effects of anastrozole on neonatal rat skin.
Topics: Anastrozole; Animals; Animals, Newborn; Aromatase Inhibitors; Female; Nitriles; Rats; Rats, Sprague-Dawley; Skin; Triazoles | 2007 |
Adherence to initial adjuvant anastrozole therapy among women with early-stage breast cancer.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Prescriptions; Female; Humans; Longitudinal Studies; Middle Aged; Neoplasm Staging; Nitriles; Patient Compliance; Triazoles | 2008 |
Erythema multiforme after radiotherapy with aromatase inhibitor administration in breast-conservation treatment for breast cancer.
Topics: Administration, Oral; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Erythema Multiforme; Female; Humans; Middle Aged; Nitriles; Radiotherapy; Triazoles | 2008 |
[Efficacy of sequential treatment with anastrozole following exemestane compared with exemestane following anastrozole in patients with metastatic breast cancer].
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Metastasis; Nitriles; Retrospective Studies; Survival Rate; Triazoles | 2008 |
Anticancer therapy in patients with porphyrias: evidence today.
Topics: Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Docetaxel; Epoetin Alfa; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Hematinics; Humans; Letrozole; Middle Aged; Nitriles; Porphyria, Acute Intermittent; Porphyria, Variegate; Recombinant Proteins; Risk Assessment; Taxoids; Triazoles; Uterine Neoplasms | 2008 |
Controversies in endocrine treatment: effective utilization of steroidal and nonsteroidal aromatase inhibitors: now and in the future. Forward.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2008 |
Inappropriate ATAC on tamoxifen.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Risk Assessment; Survival Analysis; Tamoxifen; Time Factors; Triazoles | 2008 |
Inappropriate ATAC on tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Diseases; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Long-term disease-free survival after hormonal therapy of a patient with recurrent low grade endometrial stromal sarcoma: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Combined Modality Therapy; Disease-Free Survival; Endometrial Neoplasms; Female; Goserelin; Humans; Lung Neoplasms; Neoplasm Recurrence, Local; Nitriles; Sarcoma, Endometrial Stromal; Triazoles | 2009 |
Process analytical technology: non-destructive assessment of anastrozole entrapment within PLGA microparticles by near infrared spectroscopy and chemical imaging.
Topics: Algorithms; Anastrozole; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Models, Chemical; Models, Statistical; Multivariate Analysis; Nitriles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectroscopy, Near-Infrared; Technology, Pharmaceutical; Triazoles | 2008 |
The aromatase inhibitor anastrozole is ineffective in the treatment of precocious puberty in girls with McCune-Albright syndrome.
Topics: Anastrozole; Aromatase Inhibitors; Child; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Humans; Nitriles; Prospective Studies; Puberty, Precocious; Triazoles; Uterine Hemorrhage | 2008 |
[A case of elderly breast cancer achieving partial response by letrozole with stable disease to anastrozole as neoadjuvant endocrine therapy].
Topics: Aged, 80 and over; Anastrozole; Breast Neoplasms; Endocrine System; Female; Humans; Letrozole; Neoadjuvant Therapy; Nitriles; Postmenopause; Tomography, X-Ray Computed; Triazoles; Ultrasonography | 2008 |
Combination of anastrozole with fulvestrant in the intratumoral aromatase xenograft model.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Estradiol; Female; Fulvestrant; Humans; Mice; Mice, Nude; Nitriles; Organ Size; Ovariectomy; Receptors, Growth Factor; Signal Transduction; Triazoles; Tumor Burden; Tumor Cells, Cultured; Uterus; Xenograft Model Antitumor Assays | 2008 |
Retinal hemorrhages in anastrozole users.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Fluorescein Angiography; Humans; Middle Aged; Nitriles; Patient Selection; Retinal Hemorrhage; Retrospective Studies; Tamoxifen; Tomography, Optical Coherence; Triazoles | 2008 |
Anastrozole-associated sclerosing glomerulonephritis in a patient with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Atrophy; Breast Neoplasms; Fatal Outcome; Female; Glomerulosclerosis, Focal Segmental; Humans; Inflammation; Nitriles; Triazoles | 2007 |
Is long-term adjuvant treatment of breast cancer with anastrozole indicated?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Nitriles; Time Factors; Triazoles | 2008 |
Treatment of male infertility secondary to morbid obesity.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Follicle Stimulating Hormone; Humans; Hypogonadism; Infertility, Male; Luteinizing Hormone; Male; Nitriles; Obesity, Morbid; Spermatogenesis; Testosterone; Triazoles | 2008 |
A case of benign metastasizing leiomyoma treated by surgical castration followed by an aromatase inhibitor, anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Fallopian Tubes; Female; Humans; Hysterectomy; Leiomyoma; Lung Neoplasms; Middle Aged; Nitriles; Ovariectomy; Triazoles; Uterine Neoplasms | 2009 |
[Intensification of a diffuse chronic pain syndrome by the introduction of an aromatase inhibitor].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progression; Female; Fibromyalgia; Humans; Mastectomy; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2008 |
Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole.
Topics: Adenocarcinoma; Anastrozole; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Immunohistochemistry; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Receptors, Estrogen; Tomography, X-Ray Computed; Triazoles | 2008 |
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands.
Topics: Anastrozole; Aromatase Inhibitors; Biological Assay; Cell Line, Tumor; Coumarins; ERRalpha Estrogen-Related Receptor; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Fulvestrant; Genes, Reporter; Genistein; Humans; Letrozole; Ligands; Luciferases; Nitriles; Receptors, Estrogen; Response Elements; Tamoxifen; Thiazoles; Transfection; Triazoles | 2008 |
Persistent bilateral ureteral obstruction secondary to endometriosis despite treatment with an aromatase inhibitor.
Topics: Anastrozole; Aromatase Inhibitors; Disease Progression; Endometriosis; Female; Humans; Kidney Function Tests; Middle Aged; Nitriles; Severity of Illness Index; Stents; Treatment Failure; Triazoles; Ureteral Diseases; Ureteral Obstruction; Urologic Surgical Procedures | 2008 |
Cutaneous vasculitis in breast cancer treated with chemotherapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; ErbB Receptors; Female; Humans; Middle Aged; Nitriles; Paraneoplastic Syndromes; Skin Diseases, Vascular; Tamoxifen; Triazoles; Vasculitis | 2008 |
[Extended adjuvant hormone therapy (in breast cancer): Why? To whom? What? How long?].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Administration Schedule; Estrogen Receptor Modulators; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Tamoxifen; Time Factors; Triazoles | 2008 |
Development and validation of an improved high-throughput method for the determination of anastrozole in human plasma by LC-MS/MS and atmospheric pressure chemical ionization.
Topics: Acetonitriles; Anastrozole; Area Under Curve; Aromatase Inhibitors; Atmospheric Pressure; Chromatography, Liquid; Half-Life; Humans; Male; Methyl Ethers; Nitriles; Omeprazole; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrometry, Mass, Electrospray Ionization; Tablets; Tandem Mass Spectrometry; Therapeutic Equivalency; Time Factors; Triazoles | 2008 |
Successful management of a leiomyomatosis peritonealis disseminata with an aromatase inhibitor.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Female; Humans; Leiomyomatosis; Nitriles; Peritoneal Cavity; Postmenopause; Triazoles | 2008 |
Characterization of the weak estrogen receptor alpha agonistic activity of exemestane.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Female; Gene Expression Profiling; Humans; Microarray Analysis; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles; Tumor Cells, Cultured | 2009 |
Risk factors for joint symptoms in patients enrolled in the ATAC trial: a retrospective, exploratory analysis.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Arthralgia; Arthritis; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Drug Interactions; Female; Humans; Joint Diseases; Likelihood Functions; Logistic Models; Middle Aged; Multivariate Analysis; Nitriles; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tamoxifen; Triazoles | 2008 |
Vitreo-retinal traction and anastrozole use.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fovea Centralis; Humans; Middle Aged; Nitriles; Tamoxifen; Tomography, Optical Coherence; Triazoles | 2009 |
Screening and management of osteoporosis in breast cancer patients on aromatase inhibitors.
Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Female; Humans; Letrozole; Middle Aged; Nitriles; Osteoporosis; Retrospective Studies; Triazoles | 2008 |
Clinical trial presentations, agency guidelines, and oncology practice: findings from the arimidex, tamoxifen, alone or in combination trial.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Nitriles; Practice Guidelines as Topic; Tamoxifen; Triazoles | 2008 |
IBIS II: a breast cancer prevention trial in postmenopausal women using the aromatase inhibitor anastrozole.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chemotherapy, Adjuvant; Double-Blind Method; Etidronic Acid; Female; Humans; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Nitriles; Osteoporosis, Postmenopausal; Postmenopause; Randomized Controlled Trials as Topic; Risedronic Acid; Triazoles | 2008 |
Encapsulation and extended release of anti-cancer anastrozole by stealth nanoparticles.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Delayed-Action Preparations; Dendrimers; Drug Carriers; Nanoparticles; Nitriles; Particle Size; Polyamines; Polyethylene Glycols; Solubility; Surface Properties; Triazoles | 2008 |
Re: Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Chemotherapy, Adjuvant; Cytochrome P-450 CYP2D6; Estrogen Receptor Modulators; Female; Humans; Markov Chains; Middle Aged; Nitriles; Postmenopause; Tamoxifen; Triazoles | 2008 |
Re: Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Asian People; Breast Neoplasms; Chemotherapy, Adjuvant; Cytochrome P-450 CYP2D6; Decision Making; Disease-Free Survival; Estrogen Receptor Modulators; Female; Genotype; Humans; Markov Chains; Middle Aged; Nitriles; Patient Participation; Postmenopause; Tamoxifen; Triazoles | 2008 |
Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics.
Topics: Aged; Analysis of Variance; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Letrozole; Lymphatic Metastasis; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Receptors, Estrogen; Reproducibility of Results; Risk Assessment; Risk Factors; Tamoxifen; Treatment Outcome; Triazoles | 2008 |
Primary uterine rhabdomyosarcoma in a patient with a history of breast cancer and gastrointestinal stromal tumor.
Topics: Aged; Anastrozole; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Gastrointestinal Stromal Tumors; Humans; Neoplasms, Second Primary; Nitriles; Rhabdomyosarcoma, Embryonal; Stomach; Triazoles; Uterine Neoplasms; Uterus | 2008 |
[A case of recurrent breast cancer with multiple lung metastases responding to anastrozole monotherapy].
Topics: Anastrozole; Biomarkers, Tumor; Breast Neoplasms; Female; Humans; Lung Neoplasms; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Radiography; Triazoles | 2008 |
Treatment-emergent endocrine symptoms and the risk of breast cancer recurrence: a retrospective analysis of the ATAC trial.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Biomarkers, Tumor; Breast Neoplasms; Female; Hot Flashes; Humans; Joints; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Odds Ratio; Postmenopause; Predictive Value of Tests; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Tamoxifen; Treatment Outcome; Triazoles; Vasomotor System | 2008 |
A lower incidence of gynecologic adverse events and interventions with anastrozole than with tamoxifen in the ATAC trial.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Genital Diseases, Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Retrospective Studies; Tamoxifen; Triazoles | 2009 |
Effects of 17beta-estradiol on rat urinary bladder: gender differences in anoxia-glucopenia and reperfusion damage.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Glucose; Hypoxia; In Vitro Techniques; Injections, Subcutaneous; Male; Muscle Contraction; Neuroprotective Agents; Nitriles; Rats; Rats, Wistar; Reperfusion Injury; Sex Factors; Testosterone; Time Factors; Triazoles; Urinary Bladder; Urinary Bladder Diseases | 2009 |
Anastrozole: brain draining or sparing?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Attention; Breast Neoplasms; Cognition; Humans; Memory; Nitriles; Postmenopause; Triazoles | 2008 |
Cognitive effects of hormonal therapy in early stage breast cancer patients: a prospective study.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Cognition Disorders; Female; Follow-Up Studies; Humans; Mental Recall; Middle Aged; Neoplasms, Hormone-Dependent; Neuropsychological Tests; Nitriles; Prospective Studies; Psychometrics; Reaction Time; Receptors, Estrogen; Tamoxifen; Triazoles | 2009 |
A paraneoplastic manifestation of metastatic breast cancer responding to endocrine therapy: a case report.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Creatine Kinase; Female; Humans; Immunoglobulin G; Middle Aged; Neoplasm Metastasis; Nitriles; Paraneoplastic Syndromes; Triazoles | 2008 |
Adherence to adjuvant endocrine therapy in postmenopausal women with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Patient Compliance; Postmenopause; Tamoxifen; Triazoles | 2009 |
Effectiveness of anastrozole and cyproterone acetate in two brothers with familial male precocious puberty.
Topics: Anastrozole; Androgen Antagonists; Aromatase Inhibitors; Body Height; Child, Preschool; Cyproterone Acetate; Humans; Infant; Male; Mutation; Nitriles; Puberty, Precocious; Receptors, LH; Treatment Outcome; Triazoles | 2008 |
Successful treatment of refractory endometriosis-related chronic pelvic pain with aromatase inhibitors in premenopausal patients.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Chronic Disease; Dose-Response Relationship, Drug; Endometriosis; Estradiol; Female; Follicle Stimulating Hormone; Humans; Letrozole; Luteinizing Hormone; Nitriles; Pelvic Pain; Premenopause; Treatment Outcome; Triazoles; Uterine Diseases | 2009 |
Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Nitriles; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vagina | 2009 |
Mean platelet volume increase after tamoxifen, but not after anastrazole in adjuvant therapy of breast cancer.
Topics: Adult; Aged; Anastrozole; Blood Platelets; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Nitriles; Platelet Count; Retrospective Studies; Tamoxifen; Triazoles | 2010 |
Collaborative work on evaluation of ovarian toxicity. 8) Two- or four-week repeated-dose studies and fertility study of Anastrozole in female rats.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Corpus Luteum; Drug Administration Schedule; Estrous Cycle; Female; Fertility; Japan; Male; Nitriles; Organ Size; Ovarian Follicle; Ovary; Pregnancy; Public-Private Sector Partnerships; Rats; Rats, Inbred F344; Societies, Scientific; Specific Pathogen-Free Organisms; Toxicity Tests; Triazoles; Uterus | 2009 |
Sustained effect of the aromatase inhibitors anastrozole and letrozole on endometrial thickness in patients with endometrial hyperplasia and endometrial carcinoma.
Topics: Aged; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Carcinoma; Disease Progression; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Humans; Letrozole; Middle Aged; Neoplasm Metastasis; Nitriles; Organ Size; Retrospective Studies; Time Factors; Triazoles | 2009 |
Initial treatment and changes in adjuvant endocrine therapy for early stage breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Neoplasm Staging; Nitriles; Retrospective Studies; Tamoxifen; Treatment Outcome; Triazoles | 2009 |
[A case of metastatic breast cancer resistant to anastrozole treatment responding to high-dose toremifene].
Topics: Anastrozole; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Lymph Node Excision; Lymphatic Metastasis; Mastectomy; Middle Aged; Nitriles; Tomography, X-Ray Computed; Toremifene; Triazoles | 2009 |
Combined Src and aromatase inhibition impairs human breast cancer growth in vivo and bypass pathways are activated in AZD0530-resistant tumors.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzodioxoles; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; CSK Tyrosine-Protein Kinase; Cyclin-Dependent Kinase Inhibitor p27; Drug Resistance, Neoplasm; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinases; Nitriles; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinazolines; Signal Transduction; src-Family Kinases; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2009 |
[Nineteen years postoperatively, anastrozole, UFT and cyclophosphamide combination therapy remained effective against recurrent hormone responsive breast cancer with intraabdominal lymphnode, pleural, skin and bone metastases in old age following sixteen-
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Neoplasms; Breast Neoplasms; Cyclophosphamide; Female; Hormone Replacement Therapy; Humans; Lymphatic Metastasis; Nitriles; Pleural Neoplasms; Radiography; Recurrence; Skin Neoplasms; Tamoxifen; Tegafur; Time Factors; Triazoles; Uracil | 2009 |
Pharmacokinetics and pharmacodynamics of anastrozole in pubertal boys with recent-onset gynecomastia.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Breast; Child; Gynecomastia; Humans; Male; Nitriles; Puberty; Triazoles | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Data Interpretation, Statistical; Diphosphonates; Disease-Free Survival; Drug Therapy, Combination; Female; Goserelin; Humans; Imidazoles; Nitriles; Premenopause; Tamoxifen; Triazoles; Zoledronic Acid | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Disease-Free Survival; Drug Therapy, Combination; Female; Goserelin; Humans; Imidazoles; Nitriles; Premenopause; Tamoxifen; Triazoles; Zoledronic Acid | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Therapy, Combination; Female; Goserelin; Humans; Nitriles; Premenopause; Tamoxifen; Triazoles | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Confidence Intervals; Diphosphonates; Disease-Free Survival; Drug Therapy, Combination; Female; Humans; Imidazoles; Nitriles; Premenopause; Tamoxifen; Triazoles; Zoledronic Acid | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density Conservation Agents; Breast Neoplasms; Diphosphonates; Drug Therapy, Combination; Humans; Imidazoles; Nitriles; Premenopause; Triazoles; Vitamin D; Vitamins; Zoledronic Acid | 2009 |
Endocrine therapy plus zoledronic acid in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Diphosphonates; Disease-Free Survival; Drug Therapy, Combination; Female; Goserelin; Humans; Imidazoles; Nitriles; Premenopause; Receptor, ErbB-2; Tamoxifen; Triazoles; Zoledronic Acid | 2009 |
Effects of morphine on testosterone levels in rat C6 glioma cells: modulation by anastrozole.
Topics: Anastrozole; Animals; Cell Line, Tumor; Glioma; Morphine; Nitriles; Rats; Testosterone; Triazoles | 2009 |
Biological profile of oestrogen receptor positive primary breast cancers in the elderly and response to primary endocrine therapy.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles | 2009 |
Adverse events and bone health during anastrozole therapy in postmenopausal Japanese breast cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Arthralgia; Bone Density; Breast Neoplasms; Cerebral Infarction; Female; Follow-Up Studies; Fractures, Bone; Humans; Incidence; Japan; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Survival Rate; Treatment Outcome; Triazoles | 2010 |
Differential effects of aromatase inhibitors and antiestrogens on estrogen receptor expression in breast cancer cells.
Topics: Anastrozole; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Fulvestrant; Humans; Letrozole; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Triazoles; Tumor Cells, Cultured | 2009 |
LC and LC-MS/MS study of forced decomposition behavior of anastrozole and establishment of validated stability-indicating analytical method for impurities estimation in low dose anastrozole tablets.
Topics: Anastrozole; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Stability; Humidity; Hydrolysis; Nitriles; Oxidation-Reduction; Photolysis; Quality Control; Tandem Mass Spectrometry; Temperature; Triazoles | 2009 |
Hemicentral retinal artery occlusion in a breast cancer patient using anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Retinal Artery Occlusion; Triazoles | 2009 |
Metastasis of lobular breast carcinoma to the uterus in a patient under anastrozole therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Lobular; Diagnosis, Differential; Female; Humans; Middle Aged; Nitriles; Triazoles; Uterine Neoplasms | 2009 |
Promising effect of aromatase inhibitors on recurrent granulosa cell tumors.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Female; Granulosa Cell Tumor; Humans; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Ovarian Neoplasms; Ovariectomy; Prognosis; Treatment Outcome; Triazoles | 2009 |
[Criteria for evaluating the effectiveness of aromatase inhibitors in the neoadjuvant treatment of patients with endometrial carcinoma].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Chemotherapy, Adjuvant; Endometrial Neoplasms; Estradiol; Female; Humans; Ki-67 Antigen; Letrozole; Middle Aged; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Receptors, Progesterone; Time Factors; Treatment Outcome; Triazoles | 2009 |
Concurrent administration of chemo-endocrine therapy for postmenopausal breast cancer patients.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cyclophosphamide; Epirubicin; Female; Fluorouracil; Humans; Middle Aged; Nitriles; Paclitaxel; Postmenopause; Treatment Outcome; Triazoles; Tumor Burden | 2010 |
A case of uterine tumour resembling ovarian sex cord tumour responding to second-line, single agent anastrazole.
Topics: Anastrozole; Diagnosis, Differential; Female; Humans; Middle Aged; Nitriles; Ovarian Neoplasms; Triazoles; Uterine Neoplasms | 2009 |
How to treat hormone receptor-positive, human epidermal growth factor receptor 2-amplified breast cancer.
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Lapatinib; Nitriles; Prognosis; Quinazolines; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Risk Assessment; Survival Analysis; Time Factors; Trastuzumab; Triazoles | 2009 |
NCCN Guideline update: Breast Cancer Version 1.2004.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Therapy; Female; Humans; Letrozole; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Neoplasms, Hormone-Dependent; Nitriles; Receptors, Estrogen; Tamoxifen; Triazoles | 2004 |
Evaluation of plasma and tissue estrogen suppression with third-generation aromatase inhibitors: of relevance to clinical understanding?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Nitriles; Postmenopause; Triazoles | 2010 |
Effect of aromatase inhibitors on ectopic endometrial growth and peritoneal environment in a mouse model of endometriosis.
Topics: Anastrozole; Animals; Apoptosis; Aromatase; Aromatase Inhibitors; Ascitic Fluid; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Female; Letrozole; Mice; Nitriles; Prostaglandins E; Triazoles; Vascular Endothelial Growth Factor A | 2010 |
Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Letrozole; Nitriles; Pharmacogenetics; Receptors, Estrogen; Tamoxifen; Triazoles | 2010 |
Impact of aromatase inhibitors on bone health in breast cancer patients.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Breast Neoplasms; Calcium; Diphosphonates; Female; Humans; Letrozole; Nitriles; Triazoles; Vitamin D | 2010 |
Aromatase inhibition in male breast cancer patients: biological and clinical implications.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms, Male; Carcinoma; Estradiol; Humans; Letrozole; Male; Middle Aged; Neoplasm Metastasis; Nitriles; Retrospective Studies; Survival Analysis; Testosterone; Treatment Outcome; Triazoles | 2010 |
Molecular characterization of aromatase inhibitor-resistant, tamoxifen-resistant and LTEDaro cell lines.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2010 |
Musculoskeletal manifestations in patients with malignant disease.
Topics: Adult; Aged; Analysis of Variance; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Female; Humans; Joint Diseases; Letrozole; Male; Middle Aged; Muscular Diseases; Neoplasms; Nitriles; Osteoporosis; Statistics, Nonparametric; Triazoles | 2010 |
A remarkable case of cutaneous metastatic breast carcinoma.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Docetaxel; Epirubicin; Female; Humans; Mammaplasty; Mastectomy, Modified Radical; Middle Aged; Neoadjuvant Therapy; Nitriles; Radiography; Skin Neoplasms; Taxoids; Triazoles | 2009 |
Drug-induced pruritic micropapular eruption: anastrozole, a commonly used aromatase inhibitor.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Combined Modality Therapy; Diagnostic Errors; Drug Eruptions; Female; Humans; Mastectomy, Segmental; Nitriles; Postoperative Complications; Pruritus; Radiotherapy, Adjuvant; Scabies; Triazoles | 2009 |
Treatment of autonomous ovarian follicular cyst with long-term anastrozole therapy.
Topics: Anastrozole; Aromatase Inhibitors; Child; Female; Humans; Nitriles; Ovarian Cysts; Puberty, Precocious; Recurrence; Triazoles | 2009 |
A simple, selective and rapid validated method for estimation of anastrazole in human plasma by liquid chromatography-tandem mass spectrometry and its application to bioequivalence study.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Chromatography, Liquid; Humans; Nitriles; Tandem Mass Spectrometry; Therapeutic Equivalency; Triazoles | 2010 |
Serum estradiol should be monitored not only during the peri-menopausal period but also the post-menopausal period at the time of aromatase inhibitor administration.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Estradiol; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Nitriles; Perimenopause; Postmenopause; Triazoles | 2009 |
ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin-1; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Nitriles; Pyrrolidines; Receptor, Endothelin A; Tamoxifen; Time Factors; Triazoles; Tumor Burden; Xenograft Model Antitumor Assays | 2010 |
Testosterone: more is not always better.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Bone and Bones; Bone Density; Estrogens; Humans; Male; Middle Aged; Nitriles; Randomized Controlled Trials as Topic; Receptors, Androgen; Testosterone; Triazoles | 2009 |
Role of testosterone/estradiol ratio in predicting the efficacy of tamoxifen citrate treatment in idiopathic oligoasthenoteratozoospermic men.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Estradiol; Humans; Male; Nitriles; Oligospermia; Predictive Value of Tests; Sperm Motility; Spermatozoa; Tamoxifen; Testosterone; Triazoles | 2009 |
Retrospective analysis of concurrent vs. sequential administration of radiotherapy and hormone therapy using aromatase inhibitor for hormone receptor-positive postmenopausal breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Radiotherapy, Adjuvant; Retrospective Studies; Triazoles | 2009 |
[A case of inflammatory breast cancer responding to anastrozole].
Topics: Adenocarcinoma, Scirrhous; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Inflammation; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2009 |
[A successful case of advanced breast cancer of the elderly treated with the only breast-hormone therapy as PST].
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aortic Aneurysm, Thoracic; Aortic Dissection; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Hypertension; Nitriles; Receptors, Estrogen; Triazoles | 2009 |
Antiproliferative effects of anastrozole, methotrexate, and 5-fluorouracil on endometriosis in vitro and in vivo.
Topics: Adult; Anastrozole; Animals; Antineoplastic Agents; Biopsy; Case-Control Studies; Cell Proliferation; Cell Survival; Cells, Cultured; Endometriosis; Endometrium; Female; Fluorouracil; Humans; Methotrexate; Mice; Mice, Nude; Nitriles; Progesterone; Transplantation, Heterologous; Triazoles; Uterine Diseases | 2010 |
Relationship between plasma estradiol levels and estrogen-responsive gene expression in estrogen receptor-positive breast cancer in postmenopausal women.
Topics: Aged; Anastrozole; Breast Neoplasms; Estradiol; Estrogens; Female; Gene Expression Profiling; Humans; Ki-67 Antigen; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2010 |
Transdermal patches for site-specific delivery of anastrozole: In vitro and local tissue disposition evaluation.
Topics: Adhesives; Administration, Cutaneous; Administration, Oral; Anastrozole; Animals; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Female; Mice; Mice, Inbred Strains; Nitriles; Permeability; Rats; Rats, Wistar; Skin; Skin Absorption; Tissue Distribution; Triazoles | 2010 |
Concordance between semiquantitative immunohistochemical assay and oncotype DX RT-PCR assay for estrogen and progesterone receptors.
Topics: Anastrozole; Anesthetics, Combined; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Early Detection of Cancer; Female; Gonadal Steroid Hormones; Humans; Immunohistochemistry; Neoplasm Recurrence, Local; Nitriles; Practice Guidelines as Topic; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Reverse Transcriptase Polymerase Chain Reaction; Tamoxifen; Triazoles | 2010 |
Comparison of the effects of raloxifene and anastrozole on experimental endometriosis.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Endometriosis; Female; Nitriles; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Single-Blind Method; Triazoles | 2010 |
Breast cancer risk assessment in a mammography screening program and participation in the IBIS-II chemoprevention trial.
Topics: Age Factors; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemoprevention; Double-Blind Method; Female; Health Knowledge, Attitudes, Practice; Humans; Mammography; Mass Screening; Middle Aged; Nitriles; Patient Selection; Randomized Controlled Trials as Topic; Risk Factors; Socioeconomic Factors; Surveys and Questionnaires; Triazoles | 2010 |
Treatment of familial male-limited precocious puberty (testotoxicosis) with anastrozole and bicalutamide in a boy with a novel mutation in the luteinizing hormone receptor.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Body Height; Body Weight; Child Development; Child, Preschool; Drug Therapy, Combination; Humans; Male; Nitriles; Point Mutation; Puberty, Precocious; Receptors, LH; Tosyl Compounds; Triazoles | 2009 |
Endocrine therapy is associated with low performance on some estrogen-sensitive cognitive tasks in postmenopausal women with breast cancer.
Topics: Aged; Anastrozole; Breast Neoplasms; Case-Control Studies; Cognition Disorders; Estrogen Antagonists; Fatigue; Female; Humans; Memory Disorders; Middle Aged; Mood Disorders; Neuropsychological Tests; Nitriles; Postmenopause; Statistics, Nonparametric; Surveys and Questionnaires; Tamoxifen; Triazoles | 2010 |
Variation in anastrozole metabolism and pharmacodynamics in women with early breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Breast Neoplasms; Cohort Studies; Dose-Response Relationship, Drug; Estrogens; Estrone; Female; Humans; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Testosterone; Triazoles | 2010 |
Aromatase inhibitor anastrozole as a second-line hormonal treatment to a recurrent low-grade endometrial stromal sarcoma: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometrial Neoplasms; Endometrial Stromal Tumors; Female; Humans; Medroxyprogesterone Acetate; Neoplasm Grading; Neoplasm Recurrence, Local; Nitriles; Triazoles | 2011 |
[Endometrial stromal sarcoma: complete response to therapy with aromatase-inhibitor, anastrozole].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Endometrial Neoplasms; Female; Humans; Nitriles; Remission Induction; Sarcoma, Endometrial Stromal; Tomography, X-Ray Computed; Treatment Outcome; Triazoles | 2010 |
[Goserelin plus anastrozole in the treatment of premenopausal patients with metastatic breast cancer].
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Goserelin; Humans; Middle Aged; Nitriles; Premenopause; Prognosis; Survival Rate; Treatment Outcome; Triazoles | 2010 |
Gene expression profiling and prediction of response to hormonal neoadjuvant treatment with anastrozole in surgically resectable breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Gene Expression; Gene Expression Profiling; Humans; Neoadjuvant Therapy; Nitriles; Reverse Transcriptase Polymerase Chain Reaction; Triazoles | 2010 |
Predictors of non-adherence to aromatase inhibitors among commercially insured women with breast cancer.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Databases as Topic; Delivery of Health Care; Drug Costs; Female; Health Knowledge, Attitudes, Practice; Humans; Insurance, Health; Letrozole; Logistic Models; Medication Adherence; Middle Aged; Nitriles; Odds Ratio; Postmenopause; Retrospective Studies; Risk Assessment; Risk Factors; Treatment Outcome; Triazoles; United States | 2011 |
Obesity and hormone therapy in breast cancer: an unfinished puzzle.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Estrogen Antagonists; Female; Humans; Menopause; Nitriles; Obesity; Tamoxifen; Triazoles | 2010 |
Impact of the estrus cycle and reduction in estrogen levels with aromatase inhibition, on renal function and nitric oxide activity in female rats.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Estradiol; Estrogens; Estrous Cycle; Female; Hemodynamics; Kidney; Nitric Oxide; Nitric Oxide Synthase; Nitriles; Rats; Rats, Sprague-Dawley; Sexual Abstinence; Triazoles | 2010 |
Rheumatoid arthritis and aromatase inhibitors.
Topics: Adenocarcinoma; Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthritis, Rheumatoid; Breast Neoplasms; Carcinoma, Ductal; Combined Modality Therapy; Female; Humans; Letrozole; Middle Aged; Nitriles; Triazoles | 2011 |
Influence of concurrent anastrozole on acute and late side effects of whole breast radiotherapy.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Administration Schedule; Female; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Pennsylvania; Radiation Injuries; Radiotherapy, Adjuvant; Retrospective Studies; Time Factors; Triazoles | 2011 |
An ultraperformance liquid chromatography-tandem mass spectrometry method for determination of anastrozole in human plasma and its application to a pharmacokinetic study.
Topics: Administration, Oral; Anastrozole; Chromatography, High Pressure Liquid; Humans; Least-Squares Analysis; Male; Nitriles; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Triazoles | 2011 |
Results of the Zometa cost-utility model for the german healthcare system based on the results of the ABCSG-12 study.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Breast Neoplasms; Cost-Benefit Analysis; Diphosphonates; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Costs; Female; Germany; Goserelin; Humans; Imidazoles; Markov Chains; Monte Carlo Method; Multicenter Studies as Topic; National Health Programs; Neoplasms, Multiple Primary; Nitriles; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles; Zoledronic Acid | 2010 |
A rare case of breast cancer metastasis.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Female; Humans; Kidney Neoplasms; Mastectomy, Modified Radical; Middle Aged; Nephrectomy; Nitriles; Triazoles | 2010 |
The differences in outcome between ATAC and BIG 1-98 suggest efficacy differences between these two nonsteroidal AIs.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Letrozole; Nitriles; Research Design; Tamoxifen; Treatment Outcome; Triazoles | 2010 |
[Clinical significance and pathological evaluation of neoadjuvant chemotherapy in breast cancer].
Topics: Anastrozole; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Female; Humans; Neoadjuvant Therapy; Nitriles; Taxoids; Trastuzumab; Treatment Outcome; Triazoles | 2010 |
Evaluation of the psychometric properties of the BCPT Symptom Checklist with a sample of breast cancer patients before and after adjuvant therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Checklist; Chemotherapy, Adjuvant; Cognition; Dyspareunia; Female; Hot Flashes; Humans; Middle Aged; Nausea; Nitriles; Pain; Psychometrics; Reproducibility of Results; Self Report; Triazoles; Urinary Incontinence; Weight Loss | 2011 |
[Inhibitory effect of Jiawei Sanleng pill medicated serum on estrogen production and its influence on apoptosis of human endometrial cells of endometriosis].
Topics: Anastrozole; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endometriosis; Endometrium; Estradiol; Estrogens; Female; Flow Cytometry; Humans; Nitriles; Plants, Medicinal; Rats; Rats, Wistar; Serum; Time Factors; Triazoles | 2010 |
Cognitive changes associated with endocrine therapy for breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Female; Humans; Letrozole; Memory; Neoplasms, Hormone-Dependent; Nitriles; Prospective Studies; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles; United States; Women's Health | 2010 |
Rectal metastasis from lobular carcinoma of the breast: a case report.
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Lobular; Female; Humans; Nitriles; Rectal Neoplasms; Treatment Outcome; Triazoles | 2010 |
Bicalutamide and third-generation aromatase inhibitors in testotoxicosis.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Child, Preschool; Humans; Letrozole; Male; Nitriles; Puberty, Precocious; Testosterone; Tosyl Compounds; Triazoles | 2010 |
[An elderly advanced breast cancer with a good response to anastrozole].
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Neoplasm Staging; Nitriles; Tomography, X-Ray Computed; Triazoles; Ultrasonography | 2010 |
Managing bone health in women with breast cancer under adjuvant treatment with aromatase inhibitors: pretreatment bone mineral density is important.
Topics: Anastrozole; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Chemotherapy, Adjuvant; Diphosphonates; Drug Therapy, Combination; Female; Humans; Nitriles; Osteoporosis; Triazoles | 2010 |
Development and validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of tamoxifen, anastrozole, and letrozole in human plasma and its application to a clinical study.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Breast Neoplasms; Chromatography, Liquid; Female; Humans; Letrozole; Middle Aged; Nitriles; Selective Estrogen Receptor Modulators; Tamoxifen; Tandem Mass Spectrometry; Triazoles | 2010 |
Cost effectiveness of letrozole versus anastrozole in postmenopausal women with HR+ early-stage breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Ductal, Breast; Cost-Benefit Analysis; Drug Substitution; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles; United Kingdom; United States | 2010 |
Oral fluoropyrimidine may augment the efficacy of aromatase inhibitor via the down-regulation of estrogen receptor in estrogen-responsive breast cancer xenografts.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Blotting, Western; Breast Neoplasms; Cell Proliferation; Doxorubicin; Drug Combinations; Estrogen Receptor alpha; Estrogens; Female; Fluorouracil; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Oxonic Acid; Paclitaxel; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tegafur; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured; Uracil | 2011 |
In vivo treatments with fulvestrant and anastrozole differentially affect gene expression in the rat efferent ductules.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Ejaculatory Ducts; Estradiol; Fulvestrant; Gene Expression Regulation; Male; Nitriles; Rats; Rats, Wistar; Sp1 Transcription Factor; Testosterone; Transcription Factor AP-1; Triazoles | 2011 |
Suppression of ovarian function in combination with an aromatase inhibitor as treatment for advanced breast cancer in pre-menopausal women.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Gonadotropin-Releasing Hormone; Goserelin; Hormones; Humans; Middle Aged; Nitriles; Ovary; Premenopause; Tamoxifen; Triazoles | 2010 |
Cortical and trabecular bone at the radius and tibia in postmenopausal breast cancer patients: a Peripheral Quantitative Computed Tomography (pQCT) study.
Topics: Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Radiography; Radius; Tibia; Triazoles | 2011 |
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Chromosome Mapping; Chromosomes, Human, Pair 14; Clinical Trials, Phase III as Topic; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Genotype; Humans; Logistic Models; Middle Aged; Musculoskeletal System; Neoplasm Staging; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Proto-Oncogene Proteins; Randomized Controlled Trials as Topic; Receptors, Interleukin-17; Retrospective Studies; Severity of Illness Index; Triazoles | 2010 |
What is the value of the 21 gene recurrence score in HER2-negative patients?
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Kaplan-Meier Estimate; Nitriles; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; RNA, Neoplasm; Tamoxifen; Triazoles | 2010 |
Combining luteinising hormone releasing hormone agonists and aromatase inhibitors in breast cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Goserelin; Humans; Luteinizing Hormone; Nitriles; Triazoles | 2010 |
Expression of estrogen receptor beta and phosphorylation of estrogen receptor alpha serine 167 correlate with progression-free survival in patients with metastatic breast cancer treated with aromatase inhibitors.
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Estrogen Receptor alpha; Estrogen Receptor beta; Fadrozole; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Nitriles; Phosphorylation; Predictive Value of Tests; Prognosis; Retrospective Studies; Serine; Tamoxifen; Triazoles | 2010 |
10 years of ATAC: one question answered, many others unresolved.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Nitriles; Tamoxifen; Triazoles | 2010 |
[Advanced breast cancer in a patient achieving long-term SD after letrozole administration for liver metastasis developing during anastrozole therapy].
Topics: Aged; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Letrozole; Liver Neoplasms; Nitriles; Triazoles | 2010 |
A novel approach for long-term oral drug administration in animal research.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Protein Precursor; Anastrozole; Animal Experimentation; Animals; Antipsychotic Agents; Body Weight; Chromatography, Liquid; Disease Models, Animal; Female; Gels; Humans; Mass Spectrometry; Mice; Mice, Transgenic; Nitriles; Presenilin-1; Reproducibility of Results; tau Proteins; Triazoles | 2011 |
Does anastrozole affect bone resorption similarly in early and late postmenopausal women?
Topics: Age Factors; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Bone Density; Bone Resorption; Breast Neoplasms; Carcinoma; Case-Control Studies; Collagen Type I; Cross-Sectional Studies; Female; Humans; Middle Aged; Nitriles; Osteoporosis, Postmenopausal; Peptides; Postmenopause; Risk Factors; Triazoles | 2011 |
In vitro and in vivo oxidative metabolism and glucuronidation of anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chromatography, Liquid; Cytochrome P-450 CYP3A; Female; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Metabolic Networks and Pathways; Microsomes, Liver; Nitriles; Oxidation-Reduction; Tandem Mass Spectrometry; Triazoles | 2010 |
[A case of stage IV breast cancer with bone metastases that responded well for long-term to hormonal therapy].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Diphosphonates; Female; Gonadotropin-Releasing Hormone; Humans; Middle Aged; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Triazoles | 2010 |
Aromatase inhibitor-induced loss of grip strength is body mass index dependent: hypothesis-generating findings for its pathogenesis.
Topics: Aged; Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Body Mass Index; Breast Neoplasms; Cohort Studies; Female; Hand Strength; Humans; Letrozole; Middle Aged; Musculoskeletal Diseases; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Syndrome; Tamoxifen; Triazoles | 2011 |
Risk of Ipsilateral breast tumor recurrence in patients treated with Tamoxifen or Anastrozole following breast-conserving surgery with or without radiotherapy.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Radiotherapy Dosage; Retrospective Studies; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Anastrozole can cause severe hypercalcaemia mimicking primary hyperparathyroidism.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Calcium; Female; Humans; Hypercalcemia; Hyperparathyroidism, Primary; Nitriles; Parathyroid Hormone; Triazoles | 2014 |
Close and stable relationship between proliferation and a hypoxia metagene in aromatase inhibitor-treated ER-positive breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Cell Hypoxia; Cell Proliferation; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genes, Neoplasm; Humans; Nitriles; Predictive Value of Tests; Receptors, Estrogen; Sensitivity and Specificity; Triazoles | 2011 |
Prepubertal gynecomastia in two monozygotic twins with Peutz-Jeghers syndrome: two years' treatment with anastrozole and genetic study.
Topics: Anastrozole; Aromatase Inhibitors; Child; Diseases in Twins; Genetics; Gynecomastia; Humans; Male; Nitriles; Peutz-Jeghers Syndrome; Puberty; Sequence Analysis, DNA; Time Factors; Triazoles; Twins, Monozygotic | 2011 |
A gene expression signature from human breast cancer cells with acquired hormone independence identifies MYC as a mediator of antiestrogen resistance.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemotherapy, Adjuvant; Disease-Free Survival; Drug Resistance, Neoplasm; Estrogen Receptor Modulators; Female; Gene Expression Profiling; Genetic Association Studies; Humans; Kaplan-Meier Estimate; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Neoplasm Recurrence, Local; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Proportional Hazards Models; Proto-Oncogene Proteins c-myc; RNA Interference; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Anastrozole versus clomiphene citrate: which is better for ovulation induction?
Topics: Anastrozole; Aromatase Inhibitors; Clinical Trials, Phase II as Topic; Clomiphene; Female; Fertility Agents, Female; Humans; Infertility, Female; Nitriles; Ovulation Induction; Pregnancy; Pregnancy Rate; Randomized Controlled Trials as Topic; Treatment Outcome; Triazoles | 2011 |
10-year analysis of the ATAC trial: wrong conclusion?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Nitriles; Postmenopause; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Premenopausal hormone-responsive breast cancer with extensive axillary nodes involvement: total estrogen blockade and chemotherapy.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carboplatin; Combined Modality Therapy; Docetaxel; Epirubicin; Estriol; Estrogen Antagonists; Female; Humans; Ifosfamide; Leuprolide; Lymphatic Metastasis; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Taxoids; Triazoles; Tumor Necrosis Factor Ligand Superfamily Member 15 | 2011 |
Sustained release optimized formulation of anastrozole-loaded chitosan microspheres: in vitro and in vivo evaluation.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Area Under Curve; Breast Neoplasms; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Diffusion; Glutaral; Humans; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Microspheres; Nitriles; Particle Size; Polymers; Spectroscopy, Fourier Transform Infrared; Triazoles | 2011 |
Association between breast cancer subtypes and response to neoadjuvant anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Neoadjuvant Therapy; Neoplasm Staging; Neoplasms, Hormone-Dependent; Nitriles; Oligonucleotide Array Sequence Analysis; Postmenopause; Receptor, ErbB-2; Receptors, Estrogen; Recurrence; Treatment Outcome; Triazoles | 2011 |
Anastrozole-related acute hepatitis with autoimmune features: a case report.
Topics: Acute Disease; Aged; Anastrozole; Antibodies, Antinuclear; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma; Female; Hepatitis, Autoimmune; Humans; Nitriles; Treatment Outcome; Triazoles | 2011 |
Predictive algorithms for adjuvant therapy: TransATAC.
Topics: Algorithms; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Ki-67 Antigen; Neoplasm Recurrence, Local; Nitriles; Prognosis; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Synthesis of α-aryl nitriles through palladium-catalyzed decarboxylative coupling of cyanoacetate salts with aryl halides and triflates.
Topics: Acetates; Anastrozole; Catalysis; Flurbiprofen; Halogens; Mesylates; Nitriles; Palladium; Salts; Triazoles | 2011 |
An in vitro model showing adaptation to long-term oestrogen deprivation highlights the clinical potential for targeting kinase pathways in combination with aromatase inhibition.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Estradiol; Estrogens; Female; Fulvestrant; Gene Expression Profiling; Humans; Insulin-Like Growth Factor I; Models, Biological; Nitriles; Postmenopause; Receptors, Estrogen; Recurrence; Triazoles | 2011 |
Ovarian hyperstimulation syndrome in a patient treated with tamoxifen for breast cancer.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Substitution; Female; Humans; Middle Aged; Nitriles; Ovarian Hyperstimulation Syndrome; Ovariectomy; Selective Estrogen Receptor Modulators; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Effect of tamoxifen or anastrozole on steroid sulfatase activity and serum androgen concentrations in postmenopausal women with breast cancer.
Topics: Anastrozole; Androgens; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Humans; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Steryl-Sulfatase; Tamoxifen; Triazoles | 2011 |
Development and validation of a sensitive liquid chromatography/tandem mass spectrometry method for the determination of exemestane in human plasma.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Chromatography, Liquid; Humans; Linear Models; Nitriles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles | 2011 |
Inhibition of estradiol synthesis attenuates renal injury in male streptozotocin-induced diabetic rats.
Topics: Acute Kidney Injury; Albuminuria; Anastrozole; Animals; Aromatase Inhibitors; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Estradiol; Interleukin-6; Male; Nitriles; Rats; Rats, Sprague-Dawley; Streptozocin; Testosterone; Transforming Growth Factor beta; Triazoles | 2011 |
Hydrophilic interaction chromatography-electrospray ionization tandem mass spectrometric analysis of anastrozole in human plasma and its application to a pharmacokinetic study.
Topics: Anastrozole; Chromatography, Liquid; Humans; Hydrophobic and Hydrophilic Interactions; Linear Models; Male; Nitriles; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazoles | 2012 |
Five-day anastrozole group in infertility needs supplemental human chorionic gonadotropin.
Topics: Anastrozole; Aromatase Inhibitors; Chorionic Gonadotropin; Clomiphene; Drug Administration Schedule; Drug Therapy, Combination; Female; Fertility Agents, Female; Humans; Infertility, Female; Nitriles; Ovulation; Ovulation Induction; Time Factors; Treatment Outcome; Triazoles | 2011 |
Inhibitory effects of calcitriol on the growth of MCF-7 breast cancer xenografts in nude mice: selective modulation of aromatase expression in vivo.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Calcitriol; Cell Line, Tumor; Cell Proliferation; Estrogens; Female; Humans; Immunohistochemistry; Letrozole; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Nitriles; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Triazoles; Vitamins; Xenograft Model Antitumor Assays | 2011 |
Does trauma or an intercurrent surgical intervention lead to a short-term increase in breast cancer recurrence rates?
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Proportional Hazards Models; Randomized Controlled Trials as Topic; Risk Factors; Surgical Procedures, Operative; Tamoxifen; Triazoles; Wounds and Injuries | 2012 |
Direct spectroscopic evidence for binding of anastrozole to the iron heme of human aromatase. Peering into the mechanism of aromatase inhibition.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Binding Sites; Computer Simulation; Electron Spin Resonance Spectroscopy; Heme; Humans; Iron; Nitriles; Quantum Theory; Triazoles | 2011 |
Changes in breast density and circulating estrogens in postmenopausal women receiving adjuvant anastrozole.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Mammography; Middle Aged; Nitriles; Postmenopause; Prognosis; Prospective Studies; Triazoles | 2011 |
Determination and characterization of degradation products of anastrozole by LC-MS/MS and NMR spectroscopy.
Topics: Anastrozole; Aromatase Inhibitors; Chromatography, Liquid; Magnetic Resonance Spectroscopy; Nitriles; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles | 2011 |
Is primary endocrine therapy effective in treating the elderly, unfit patient with breast cancer?
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Female; Humans; Letrozole; Middle Aged; Nitriles; Receptors, Estrogen; Retrospective Studies; Survival Analysis; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Effects of aromatase inhibition versus gonadectomy on hippocampal complex amyloid pathology in triple transgenic mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anastrozole; Animals; Aromatase Inhibitors; Disease Models, Animal; Female; Hippocampus; Male; Mice; Mice, Transgenic; Neurons; Nitriles; Orchiectomy; Ovariectomy; Plaque, Amyloid; Triazoles | 2012 |
[The effect of diet induced obesity on testicular tissue and serum oxidative stress parameters].
Topics: Anastrozole; Animals; Aromatase Inhibitors; Biomarkers; Body Weight; Catalase; Diet, High-Fat; Glutathione; Gonadal Steroid Hormones; Infertility, Male; Lipid Peroxidation; Lipids; Male; Nitric Oxide; Nitriles; Obesity; Oxidative Stress; Pituitary Hormones, Anterior; Random Allocation; Rats; Rats, Wistar; Spermatogenesis; Superoxide Dismutase; Superoxide Dismutase-1; Testis; Triazoles | 2012 |
The time since last menstrual period is important as a clinical predictor for non-steroidal aromatase inhibitor-related arthralgia.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Female; Humans; Incidence; Menopause; Middle Aged; Nitriles; Prospective Studies; Time Factors; Triazoles | 2011 |
Embracing the complexity of comorbidity.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Nitriles; Tamoxifen; Triazoles | 2011 |
Adjuvant sequencing of tamoxifen and anastrozole is superior to tamoxifen alone in postmenopausal women with low proliferating breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Proliferation; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Middle Aged; Nitriles; Outcome Assessment, Health Care; Postmenopause; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Tamoxifen; Triazoles | 2011 |
The breast cancer chemoprevention debate.
Topics: Anastrozole; Androstadienes; Anticarcinogenic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemoprevention; Clinical Trials as Topic; Female; Humans; Models, Statistical; Nitriles; Raloxifene Hydrochloride; Risk Assessment; Risk Factors; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2011 |
Hormone treatment without surgery for patients aged 75 years or older with operable breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Disease Progression; Female; Follow-Up Studies; Humans; Letrozole; Nitriles; Receptor, ErbB-2; Survival Rate; Tamoxifen; Treatment Outcome; Triazoles | 2012 |
Endocrine therapy, new biologicals, and new study designs for presurgical studies in breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Erlotinib Hydrochloride; Female; Gefitinib; Humans; Ki-67 Antigen; Lapatinib; Molecular Targeted Therapy; Multicenter Studies as Topic; Neoadjuvant Therapy; Nitriles; Predictive Value of Tests; Preoperative Period; Quinazolines; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Treatment Outcome; Triazoles | 2011 |
Combined treatment with bicalutamide and anastrozole in a young boy with peripheral precocious puberty due to McCune-Albright Syndrome.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Child Development; Child, Preschool; Drug Therapy, Combination; Fibrous Dysplasia, Polyostotic; Humans; Male; Nitriles; Puberty, Precocious; Tosyl Compounds; Treatment Outcome; Triazoles | 2012 |
A case of aromatase inhibitor (anastrozole)-induced side-effects successfully treated with Kampo medicines.
Topics: Aconitine; Aconitum; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Drugs, Chinese Herbal; Female; Hemorrhage; Humans; Medicine, Kampo; Middle Aged; Mucous Membrane; Nitriles; Phytotherapy; Qi; Triazoles; Vagina | 2011 |
Effect of simvastatin on the pharmacokinetics of anastrozole.
Topics: Aged; Anastrozole; Anticholesteremic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Drug Interactions; Estradiol; Estrone; Female; Humans; Middle Aged; Nitriles; Pilot Projects; Simvastatin; Triazoles | 2012 |
[Effects of anastrozole on lipid metabolism in Chinese postmenopausal women with breast cancer].
Topics: Age Factors; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Follow-Up Studies; Humans; Hyperlipidemias; Lipid Metabolism; Lipids; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Triazoles; Triglycerides | 2011 |
Effect of the aromatase inhibitor anastrozole on uterine and leiomyoma Doppler blood flow in patients scheduled for hysterectomy: a pilot study.
Topics: Adult; Anastrozole; Aromatase Inhibitors; Female; Humans; Hysterectomy; Leiomyoma; Menorrhagia; Middle Aged; Nitriles; Pilot Projects; Regional Blood Flow; Treatment Outcome; Triazoles; Ultrasonography, Doppler; Uterine Neoplasms | 2012 |
Short-term biomarker modulation prevention study of anastrozole in women at increased risk for second primary breast cancer.
Topics: Aged; Anastrozole; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Biopsy, Fine-Needle; Breast Neoplasms; DNA; Female; Genotype; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Middle Aged; Neoplasms, Second Primary; Nitriles; Polymerase Chain Reaction; Prognosis; Triazoles | 2012 |
Grover disease (transient acantholytic dermatosis) induced by anastrozole.
Topics: Acantholysis; Aged; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Ichthyosis; Nitriles; Triazoles | 2011 |
Effects of aromatase inhibitor on menopausal hyperplasia in a case of obesity.
Topics: Administration, Oral; Aged; Anastrozole; Aromatase Inhibitors; Atrophy; Endometrial Hyperplasia; Endometrium; Estradiol; Female; Humans; Menopause; Nitriles; Obesity; Time; Treatment Outcome; Triazoles; Ultrasonography; Uterine Hemorrhage | 2012 |
Prioritizing pharmacogenetic research: a value of information analysis of CYP2D6 testing to guide breast cancer treatment.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Computer Simulation; Cost-Benefit Analysis; Cytochrome P-450 CYP2D6; Decision Support Techniques; Economics, Pharmaceutical; Female; Genotype; Humans; Markov Chains; Nitriles; Pharmacogenetics; Randomized Controlled Trials as Topic; Research Design; Tamoxifen; Triazoles; United Kingdom | 2011 |
Preventive effect of risedronate on bone loss and frailty fractures in elderly women treated with anastrozole for early breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Bone Resorption; Breast Neoplasms; Calcium Carbonate; Cohort Studies; Combined Modality Therapy; Dietary Supplements; Etidronic Acid; Female; Follow-Up Studies; Humans; Neoplasm Staging; Nitriles; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Risedronic Acid; Severity of Illness Index; Triazoles; Vitamin D | 2012 |
Aromatase inhibitors in premenopausal breast cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Goserelin; Humans; Neoadjuvant Therapy; Nitriles; Tamoxifen; Triazoles | 2012 |
Deep time: the long and the short of adjuvant endocrine therapy for breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Tamoxifen; Triazoles | 2012 |
Incidence and management of arthralgias in breast cancer patients treated with aromatase inhibitors in an outpatient oncology clinic.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Female; Humans; Incidence; Neoplasms, Hormone-Dependent; Nitriles; Outpatients; Retrospective Studies; Triazoles | 2012 |
Combined inhibition of aromatase activity and dihydrotestosterone supplementation attenuates renal injury in male streptozotocin (STZ)-induced diabetic rats.
Topics: Albuminuria; Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Collagen Type IV; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Dihydrotestosterone; Disease Models, Animal; Estrogen Receptor alpha; Incidence; Male; Nitriles; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Streptozocin; Triazoles; Tumor Necrosis Factor-alpha | 2012 |
Genesis and outcome of a breast cancer trial to develop the aromatase inhibitor anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Nitriles; Randomized Controlled Trials as Topic; Triazoles | 2012 |
CYP2D6 and UGT2B7 genotype and risk of recurrence in tamoxifen-treated breast cancer patients.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Cytochrome P-450 CYP2D6; Female; Genotype; Germ-Line Mutation; Glucuronosyltransferase; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Odds Ratio; Postmenopause; Randomized Controlled Trials as Topic; Receptors, Estrogen; Receptors, Progesterone; Risk Assessment; Risk Factors; Tamoxifen; Triazoles; United Kingdom | 2012 |
Spectral characterization of the binding and conformational changes of serum albumins upon interaction with an anticancer drug, anastrozole.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Cattle; Circular Dichroism; Fluorescence Resonance Energy Transfer; Humans; Nitriles; Protein Binding; Protein Conformation; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Triazoles | 2012 |
[Effectiveness of aromatase inhibitors in comparison with metformin for neoadjuvant treatment in patients with endometrial cancer].
Topics: Adult; Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Endometrial Neoplasms; Female; Glucose; Humans; Hypoglycemic Agents; Ki-67 Antigen; Letrozole; Metformin; Middle Aged; Neoadjuvant Therapy; Neoplasm Grading; Nitriles; Treatment Outcome; Triazoles | 2011 |
[A case of recurrent breast cancer with brain metastases successfully treated with vinorelbine and anastrozole after multiple chemo-endocrine therapies].
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Receptors, Estrogen; Recurrence; Triazoles; Vinblastine; Vinorelbine | 2012 |
Combined treatment with GH and anastrozole in a pubertal boy with Cushing's disease and postsurgical GH deficiency.
Topics: Adolescent; Anastrozole; Aromatase Inhibitors; Body Height; Drug Therapy, Combination; Growth Disorders; Hormone Replacement Therapy; Human Growth Hormone; Humans; Male; Nitriles; Pituitary ACTH Hypersecretion; Triazoles | 2012 |
A priming role of local estrogen on exogenous estrogen-mediated synaptic plasticity and neuroprotection.
Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Cell Line; Cell Survival; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Hippocampus; Hydrogen Peroxide; Nervous System; Neuronal Plasticity; Neuroprotective Agents; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Triazoles; Wortmannin | 2012 |
Polyendocrine treatment in estrogen receptor-positive breast cancer: a "FACT" yet to be proven.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Nitriles; Triazoles | 2012 |
Age effect on bone mineral density changes in breast cancer patients receiving anastrozole: results from the ARBI prospective clinical trial.
Topics: Absorptiometry, Photon; Age Factors; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Breast Neoplasms; Drug Therapy, Combination; Etidronic Acid; Female; Humans; Middle Aged; Nitriles; Osteoporosis; Osteoporosis, Postmenopausal; Outcome and Process Assessment, Health Care; Prospective Studies; Randomized Controlled Trials as Topic; Risedronic Acid; Risk Assessment; Risk Factors; Time Factors; Triazoles | 2012 |
Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Double-Blind Method; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tamoxifen; Triazoles; Weight Gain | 2012 |
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Neoadjuvant Therapy; Neoplasm Proteins; Nitriles; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; Receptors, Estrogen; RNA Interference; RNA, Small Interfering; Signal Transduction; Triazoles | 2012 |
Impact of Aromatase protein variants and drug interactions in breast cancer: a molecular docking approach.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Catalytic Domain; Drug Interactions; Female; Humans; Ligands; Models, Molecular; Mutant Proteins; Nitriles; Triazoles | 2012 |
Whole-genome analysis informs breast cancer response to aromatase inhibition.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Breast Neoplasms; DNA Repair; Exome; Exons; Female; Genetic Variation; Genome, Human; Humans; Letrozole; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mutation; Nitriles; Receptors, Estrogen; Treatment Outcome; Triazoles | 2012 |
Cellular actions of testosterone in vascular cells: mechanism independent of aromatization to estradiol.
Topics: 5-alpha Reductase Inhibitors; Anastrozole; Androgen Antagonists; Animals; Aorta; Aromatase Inhibitors; Cell Adhesion; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Estradiol; Estrogen Antagonists; Female; Finasteride; Flutamide; Fulvestrant; Monocytes; Myocytes, Smooth Muscle; Nitric Oxide; Nitriles; Rats; Rats, Wistar; Testosterone; Triazoles | 2012 |
Effect of aromatase inhibitors on background parenchymal enhancement and amount of fibroglandular tissue at breast MR imaging.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Contrast Media; Female; Gadolinium DTPA; Humans; Image Enhancement; Image Interpretation, Computer-Assisted; Letrozole; Magnetic Resonance Imaging; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Retrospective Studies; Subtraction Technique; Triazoles | 2012 |
Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome.
Topics: Age Determination by Skeleton; Anastrozole; Aromatase Inhibitors; Cafe-au-Lait Spots; Child, Preschool; Female; Fibrous Dysplasia, Polyostotic; Humans; Nitriles; Prognosis; Puberty, Precocious; Triazoles; Uterine Hemorrhage | 2012 |
Inflammatory osteoarthritis which was precipitated by Arimidex and resolved with tamoxifen.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Female; Humans; Middle Aged; Nitriles; Osteoarthritis; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2010 |
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Postmenopause; Triazoles | 2012 |
Aromatase inhibition in obese women: how much is enough?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estrogens; Female; Humans; Letrozole; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2012 |
Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Carcinogens; Cell Proliferation; Estradiol; Estrogen Receptor Modulators; Female; Fulvestrant; Immunoenzyme Techniques; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nicotiana; Nitriles; Nitrosamines; Receptors, Estrogen; Triazoles | 2012 |
Comparison of the effects of aromatase inhibitors and tamoxifen on radiation-induced lung toxicity: results of an experimental study.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Combined Modality Therapy; Female; Letrozole; Nitriles; Pulmonary Fibrosis; Radiation Injuries, Experimental; Rats; Rats, Wistar; Statistics, Nonparametric; Tamoxifen; Triazoles | 2013 |
Breast cancer: Anastrozole and fulvestrant--combination to unlock efficacy.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Nitriles; Prognosis; Triazoles | 2012 |
Lichen sclerosus in a breast cancer survivor on an aromatase inhibitor: a case report.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clobetasol; Drug Eruptions; Female; Glucocorticoids; Humans; Middle Aged; Nitriles; Triazoles; Vulvar Lichen Sclerosus | 2013 |
Dry eye syndrome in aromatase inhibitor users.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Blepharitis; Breast Neoplasms; Conjunctival Diseases; Dry Eye Syndromes; Female; Humans; Keratitis; Letrozole; Middle Aged; Nitriles; Ovarian Neoplasms; Retrospective Studies; Triazoles; Vision Disorders | 2013 |
The synergistic effect of EGFR tyrosine kinase inhibitor gefitinib in combination with aromatase inhibitor anastrozole in non-small cell lung cancer cell lines.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Synergism; ErbB Receptors; Estrogen Receptor alpha; Estrogen Receptor beta; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Expression; Humans; Inhibitory Concentration 50; Lung Neoplasms; MAP Kinase Signaling System; Nitriles; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Quinazolines; Triazoles | 2012 |
EndoPredict improves the prognostic classification derived from common clinical guidelines in ER-positive, HER2-negative early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Nitriles; Practice Guidelines as Topic; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Retrospective Studies; Risk Assessment; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
Adherence evaluation of endocrine treatment in breast cancer: methodological aspects.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Data Collection; Female; Humans; Medication Adherence; Middle Aged; Nitriles; Reproducibility of Results; Surveys and Questionnaires; Time Factors; Triazoles | 2012 |
Efficacy of adjuvant aromatase inhibitor in hormone receptor-positive postmenopausal breast cancer patients according to the body mass index.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Disease-Free Survival; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Triazoles | 2012 |
Influence of ovarian and non-ovarian estrogens on weight gain in response to disruption of sweet taste--calorie relations in female rats.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Body Weight; Energy Intake; Energy Metabolism; Female; Nitriles; Ovariectomy; Rats; Rats, Sprague-Dawley; Saccharin; Sweetening Agents; Taste; Triazoles; Weight Gain | 2013 |
Anastrozole and celecoxib for endometriosis treatment, good to keep them apart?
Topics: Anastrozole; Animals; Aromatase Inhibitors; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Combinations; Drug Evaluation, Preclinical; Drug Incompatibility; Endometriosis; Female; Mesentery; Mice; Mice, Inbred BALB C; Nitriles; Peritoneal Diseases; Pyrazoles; Sulfonamides; Triazoles; Uterine Diseases | 2013 |
Aromatase inhibitors associated with knee subchondral bone expansion without cartilage loss.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Case-Control Studies; Female; Humans; Letrozole; Magnetic Resonance Imaging; Menisci, Tibial; Middle Aged; Nitriles; Postmenopause; Prospective Studies; Tibia; Triazoles | 2013 |
Budget impact analysis of everolimus for the treatment of hormone receptor positive, human epidermal growth factor receptor-2 negative (HER2-) advanced breast cancer in the United States.
Topics: Anastrozole; Antineoplastic Agents; Breast Neoplasms; Budgets; Cost-Benefit Analysis; Drug Costs; ErbB Receptors; Everolimus; Female; Health Care Costs; Humans; Letrozole; Middle Aged; Nitriles; Receptor, ErbB-2; Severity of Illness Index; Sirolimus; Treatment Failure; Triazoles; United States | 2013 |
Development and validation of a simple and sensitive high performance liquid chromatographic method for the simultaneous determination of anastrozole, bicalutamide, tamoxifen, and their synthetic impurities.
Topics: Analysis of Variance; Anastrozole; Anilides; Calibration; Chromatography, High Pressure Liquid; Limit of Detection; Nitriles; Reproducibility of Results; Tamoxifen; Tosyl Compounds; Triazoles | 2012 |
In vivo response of melatonin, gonadal activity and biochemical changes during CYP19 inhibited sex reversal in common carp Cyprinus carpio (L).
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Carps; Fadrozole; Female; Gonads; Male; Melatonin; Nitriles; Sex Differentiation; Testosterone; Triazoles | 2013 |
[Quality of life analysis of postmenopausal, early breast cancer patients treated with anastrozole (RADAR-II)].
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Health Status; Humans; Hungary; Middle Aged; Neoplasm Staging; Nitriles; Patient Satisfaction; Postmenopause; Prospective Studies; Quality of Life; Surveys and Questionnaires; Triazoles | 2012 |
Fast disintegrating films containing anastrozole as a dosage form for dysphagia patients.
Topics: Anastrozole; Animals; Deglutition Disorders; Dosage Forms; Drug Carriers; Male; Nitriles; Rats; Rats, Wistar; Solubility; Time Factors; Triazoles; X-Ray Diffraction | 2012 |
[A successful case of a super-elderly breast cancer patient treated with hormone therapy].
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy, Large-Core Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Female; Humans; Neoplasm Staging; Nitriles; Quality of Life; Triazoles; Ultrasonography | 2012 |
A multicenter prospective study to evaluate bone fracture related to adjuvant anastrozole in Japanese postmenopausal women with breast cancer: two-year interim analysis of Saitama Breast Cancer Clinical Study Group (SBCCSG-06).
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Bone Density; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Fractures, Bone; Humans; Japan; Middle Aged; Nitriles; Postmenopause; Treatment Outcome; Triazoles | 2014 |
What is the optimal endocrine therapy for postmenopausal women with hormone receptor-positive early breast cancer?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Practice Guidelines as Topic; Receptors, Estrogen; Tamoxifen; Time Factors; Triazoles | 2013 |
Potential role of UGT1A4 promoter SNPs in anastrozole pharmacogenomics.
Topics: Anastrozole; Anticonvulsants; Aromatase Inhibitors; Gene Expression Regulation, Enzymologic; Genotype; Glucuronosyltransferase; Humans; In Vitro Techniques; Inactivation, Metabolic; Lamotrigine; Microsomes, Liver; Nitriles; Polymorphism, Single Nucleotide; Sapogenins; Triazines; Triazoles | 2013 |
Acupuncture for the treatment of hot flashes in patients with breast cancer receiving antiestrogen therapy: a pilot study in Korean women.
Topics: Acupuncture Therapy; Analysis of Variance; Anastrozole; Breast Neoplasms; Estrogen Antagonists; Female; Hot Flashes; Humans; Middle Aged; Nitriles; Prospective Studies; Republic of Korea; Severity of Illness Index; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
[A case of crescentic glomerulonephritis developed under oral anastrozole treatment].
Topics: Administration, Oral; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Female; Glomerulonephritis; Humans; Nitriles; Triazoles | 2013 |
Alleviating anastrozole induced bone toxicity by selenium nanoparticles in SD rats.
Topics: Alkaline Phosphatase; Anastrozole; Animals; Aromatase Inhibitors; Bone and Bones; Cells, Cultured; Female; Humans; Nanoparticles; Nitriles; Osteoblasts; Osteoporosis; Rats; Rats, Sprague-Dawley; Selenium; Triazoles | 2013 |
Anastrozole-associated joint pain and other symptoms in patients with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Arthralgia; Breast Neoplasms; Cohort Studies; Female; Humans; Incidence; Middle Aged; Models, Statistical; Nitriles; Pain Measurement; Triazoles | 2013 |
Should all postmenopausal patients with hormone receptor-positive breast cancer receive initial therapy with aromatase inhibitors?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Disease-Free Survival; Female; Humans; Letrozole; Nitriles; Postmenopause; Receptors, Estrogen; Tamoxifen; Time Factors; Treatment Outcome; Triazoles | 2013 |
Molecular profiling of aromatase inhibitor-treated postmenopausal breast tumors identifies immune-related correlates of resistance.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Biopsy; Breast; Breast Neoplasms; Cluster Analysis; Drug Resistance, Neoplasm; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunity; Ki-67 Antigen; Middle Aged; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2013 |
[Three patients with local recurrence of ER-positive breast cancer for whom anastrozole was clinically effective].
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2013 |
Effect of selumetinib on the growth of anastrozole-resistant tumors.
Topics: Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; MAP Kinase Kinase 1; Mice; Mice, Nude; Nitriles; Ovariectomy; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases; Triazoles; Xenograft Model Antitumor Assays | 2013 |
Protective role of testosterone in ischemia-reperfusion-induced acute kidney injury.
Topics: Acute Kidney Injury; Anastrozole; Animals; Aromatase Inhibitors; Cell Adhesion Molecules; Creatinine; Male; Nitriles; Orchiectomy; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Testosterone; Triazoles; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2013 |
Molecular characterization of anastrozole resistance in breast cancer: pivotal role of the Akt/mTOR pathway in the emergence of de novo or acquired resistance and importance of combining the allosteric Akt inhibitor MK-2206 with an aromatase inhibitor.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Estrogen Receptor alpha; Female; Heterocyclic Compounds, 3-Ring; Humans; MCF-7 Cells; Neoplasm Recurrence, Local; Nitriles; Proto-Oncogene Proteins c-akt; Receptor, ErbB-2; Receptor, ErbB-3; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Triazoles | 2013 |
[Therapy concept: herceptin in combination with arimidex].
Topics: Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Germany; Humans; Neoplasm Staging; Nitriles; Prognosis; Receptor, ErbB-2; Trastuzumab; Triazoles | 2002 |
Effect of aromatase inhibitors on bone mineral density in a Japanese breast cancer population.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Asian People; Bone Density; Breast Neoplasms; Diphosphonates; Female; Humans; Letrozole; Middle Aged; Nitriles; Postmenopause; Retrospective Studies; Triazoles | 2013 |
Two-step activation prodrugs: transplatin mediated binding of chemotherapeutic agents to vitamin B12.
Topics: Anastrozole; Antineoplastic Agents; Binding Sites; Cell Proliferation; Cell Survival; Cisplatin; Cytarabine; Dacarbazine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; K562 Cells; Molecular Structure; Nitriles; Prodrugs; Structure-Activity Relationship; Triazoles; Vitamin B 12 | 2013 |
Anastrozole and RU486: Effects on estrogen receptor α and Mucin 1 expression and correlation in the MCF-7 breast cancer cell line.
Topics: Anastrozole; Estrogen Receptor alpha; Humans; Immunohistochemistry; MCF-7 Cells; Mifepristone; Mucin-1; Nitriles; Software; Triazoles | 2013 |
Investigation of the effect of active efflux at the blood-brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system.
Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; ATP Binding Cassette Transporter, Subfamily B; Blood-Brain Barrier; Brain; Cell Line; Humans; Letrozole; Male; Mice; Nitriles; Triazoles | 2013 |
Posterior reversible encephalopathy syndrome: more than meets the eye.
Topics: Anastrozole; Biopsy, Needle; Breast Neoplasms; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Progression; Electroencephalography; Fatal Outcome; Female; Humans; Immunohistochemistry; Magnetic Resonance Imaging; Mastectomy; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Neoplasms, Multiple Primary; Nitriles; Posterior Leukoencephalopathy Syndrome; Risk Assessment; Triazoles | 2013 |
Eradication of breast cancer with bone metastasis by autologous formalin-fixed tumor vaccine (AFTV) combined with palliative radiation therapy and adjuvant chemotherapy: a case report.
Topics: Anastrozole; Androstadienes; Antineoplastic Combined Chemotherapy Protocols; Autoantigens; Bone Neoplasms; Breast Neoplasms; Cancer Vaccines; Chemotherapy, Adjuvant; Combined Modality Therapy; Cyclophosphamide; Diphosphonates; Epirubicin; Female; Fixatives; Fluorouracil; Formaldehyde; Humans; Imidazoles; Magnetic Resonance Imaging; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Prognosis; Radiotherapy Dosage; Tomography, Emission-Computed, Single-Photon; Triazoles; Zoledronic Acid | 2013 |
Comparison of PAM50 risk of recurrence score with oncotype DX and IHC4 for predicting risk of distant recurrence after endocrine therapy.
Topics: Anastrozole; Breast Neoplasms; Female; Gene Expression Profiling; Humans; Neoplasm Recurrence, Local; Nitriles; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Risk; Tamoxifen; Triazoles | 2013 |
Successful testicular sperm retrieval in adolescents with Klinefelter syndrome treated with at least 1 year of topical testosterone and aromatase inhibitor.
Topics: Academic Medical Centers; Administration, Cutaneous; Adolescent; Anastrozole; Aromatase Inhibitors; Cryopreservation; Drug Therapy, Combination; Hormone Replacement Therapy; Humans; Klinefelter Syndrome; Male; Nitriles; Retrospective Studies; Semen Preservation; Sperm Retrieval; Spermatogenesis; Testosterone; Time Factors; Treatment Outcome; Triazoles | 2013 |
Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: a TransATAC study.
Topics: Anastrozole; Biomarkers, Tumor; Breast Neoplasms; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Ki-67 Antigen; Lymph Nodes; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Tamoxifen; Transcription Factors; Treatment Outcome; Triazoles | 2013 |
Management of prepubertal gynecomastia in two monozygotic twins with Peutz-Jeghers syndrome: from aromatase inhibitors to subcutaneous mastectomy.
Topics: Adrenal Glands; Anastrozole; Aromatase Inhibitors; Child; Combined Modality Therapy; Comorbidity; Diseases in Twins; Gynecomastia; Humans; Lithiasis; Male; Mastectomy, Subcutaneous; Nitriles; Peutz-Jeghers Syndrome; Recurrence; Testicular Diseases; Testis; Triazoles; Ultrasonography, Mammary | 2013 |
Application of multiple regression analysis in optimization of anastrozole-loaded PLGA nanoparticles.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Delayed-Action Preparations; Lactic Acid; Models, Chemical; Nanoparticles; Nitriles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Regression Analysis; Triazoles | 2014 |
Combination endocrine treatments unproven in breast cancer.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Nitriles; Triazoles | 2013 |
Sperm retrieval in adolescents with Klinefelter syndrome.
Topics: Anastrozole; Aromatase Inhibitors; Hormone Replacement Therapy; Humans; Klinefelter Syndrome; Male; Nitriles; Sperm Retrieval; Spermatogenesis; Testosterone; Triazoles | 2013 |
Prepubertal gynecomastia in two monozygotic twins with Peutz-Jeghers syndrome: clinical and surgical management.
Topics: Anastrozole; Aromatase Inhibitors; Breast; Child; Combined Modality Therapy; Disease Progression; Diseases in Twins; Gynecomastia; Humans; Male; Mastectomy; Nitriles; Organ Size; Peutz-Jeghers Syndrome; Testis; Triazoles; Twins, Monozygotic | 2013 |
Successful testicular sperm retrieval in adolescents with Klinefelter syndrome treated with at least 1 year of topical testosterone and aromatase inhibitor.
Topics: Anastrozole; Aromatase Inhibitors; Hormone Replacement Therapy; Humans; Klinefelter Syndrome; Male; Nitriles; Sperm Retrieval; Spermatogenesis; Testosterone; Triazoles | 2013 |
Impact of body mass index on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estradiol; Female; Humans; Letrozole; Middle Aged; Nitriles; Obesity; Postmenopause; Prospective Studies; Receptors, Estrogen; Survival Analysis; Triazoles | 2013 |
Endometrial Intracrinology--generation of an estrogen-dominated microenvironment in the secretory phase of women.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Cellular Microenvironment; Decidua; Endometrium; Estradiol; Estrone; Female; Gene Expression Regulation, Enzymologic; Humans; Menstrual Cycle; Multienzyme Complexes; Nitriles; Ovary; Pregnancy; Pregnancy Trimester, First; Primary Cell Culture; Progesterone Reductase; RNA, Messenger; Steroid Isomerases; Stromal Cells; Triazoles | 2013 |
Tardive dyskinesia associated with anastrozole.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Female; Humans; Middle Aged; Movement Disorders; Nitriles; Triazoles | 2013 |
Reduced breast cancer incidence in women treated with subcutaneous testosterone, or testosterone with anastrozole: a prospective, observational study.
Topics: Adult; Aged; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Estrogen Replacement Therapy; Female; Hormone Replacement Therapy; Humans; Incidence; Menopause; Middle Aged; Nitriles; Patient Compliance; Prospective Studies; Qualitative Research; Testosterone; Triazoles | 2013 |
Psychometric analysis of the Patient Assessment of Own Functioning Inventory in women with breast cancer.
Topics: Activities of Daily Living; Adult; Aged; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Chi-Square Distribution; Factor Analysis, Statistical; Female; Humans; Middle Aged; Neuropsychological Tests; Nitriles; Postmenopause; Prospective Studies; Psychometrics; Quality of Life; Reproducibility of Results; Triazoles | 2013 |
A polymorphism at the 3'-UTR region of the aromatase gene is associated with the efficacy of the aromatase inhibitor, anastrozole, in metastatic breast carcinoma.
Topics: 17-Hydroxysteroid Dehydrogenases; 3' Untranslated Regions; Adult; Aged; Aged, 80 and over; Alleles; Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Anastrozole; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Female; Gene Frequency; Genotype; Humans; Middle Aged; Nitriles; Polymorphism, Single Nucleotide; Proteins; Retrospective Studies; Survival Analysis; Triazoles | 2013 |
Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunoenzyme Techniques; Mammary Neoplasms, Experimental; Nitriles; Oligonucleotide Array Sequence Analysis; Rats; Real-Time Polymerase Chain Reaction; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Triazoles | 2013 |
Coadministration of anastrozole sustains therapeutic testosterone levels in hypogonadal men undergoing testosterone pellet insertion.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Drug Implants; Drug Therapy, Combination; Follicle Stimulating Hormone; Gonadotropins; Humans; Hypogonadism; Luteinizing Hormone; Male; Middle Aged; Nitriles; Off-Label Use; Retrospective Studies; Sex Hormone-Binding Globulin; Testosterone; Triazoles; United States | 2014 |
Rapid response of breast cancer to neoadjuvant intramammary testosterone-anastrozole therapy: neoadjuvant hormone therapy in breast cancer.
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Implants; Female; Humans; Mammary Glands, Human; Neoadjuvant Therapy; Nitriles; Testosterone; Triazoles; Ultrasonography | 2014 |
The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2- breast cancer patients.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Differentiation; Cell Growth Processes; Clinical Trials, Phase III as Topic; Female; Gene Expression Profiling; Humans; Neoplasm Metastasis; Neoplasm Recurrence, Local; Nitriles; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Receptors, Estrogen; Retrospective Studies; Signal Transduction; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
Extra virgin olive oil potentiates the effects of aromatase inhibitors via glutathione depletion in estrogen receptor-positive human breast cancer (MCF-7) cells.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aromatase Inhibitors; Cytochromes c; Female; Glutathione; Humans; Letrozole; MCF-7 Cells; Nitriles; Oleic Acid; Olive Oil; Plant Oils; Reactive Oxygen Species; Receptors, Estrogen; Triazoles | 2013 |
Bone mineral density and response to treatment in men younger than 50 years with testosterone deficiency and sexual dysfunction or infertility.
Topics: Age Factors; Anastrozole; Androgens; Aromatase Inhibitors; Bone Density; Clomiphene; Deficiency Diseases; Estrogen Antagonists; Humans; Infertility, Male; Male; Middle Aged; Nitriles; Retrospective Studies; Sexual Dysfunction, Physiological; Testosterone; Triazoles | 2014 |
Physiological testosterone levels enhance chondrogenic extracellular matrix synthesis by male intervertebral disc cells in vitro, but not by mesenchymal stem cells.
Topics: Adult; Aggrecans; Anastrozole; Aromatase Inhibitors; Cell Differentiation; Cell Survival; Cells, Cultured; Chondrogenesis; Collagen Type II; Extracellular Matrix; Female; Humans; In Vitro Techniques; Intervertebral Disc; Male; Mesenchymal Stem Cells; Middle Aged; Nitriles; Sex Factors; Testosterone; Transforming Growth Factor beta; Triazoles | 2014 |
Expression of estrogen-related gene markers in breast cancer tissue predicts aromatase inhibitor responsiveness.
Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; BRCA1 Protein; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Estrogens; Female; Gene Expression Regulation, Neoplastic; Genetic Markers; Humans; Hydroxyprostaglandin Dehydrogenases; Letrozole; Middle Aged; Nitriles; Receptors, Progesterone; ROC Curve; Tamoxifen; Treatment Outcome; Triazoles | 2013 |
The impact of structural uncertainty on cost-effectiveness models for adjuvant endocrine breast cancer treatments: the need for disease-specific model standardization and improved guidance.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Cost-Benefit Analysis; Female; Humans; Models, Economic; Models, Structural; Nitriles; Quality-Adjusted Life Years; Survival Analysis; Tamoxifen; Triazoles; Uncertainty | 2014 |
Impact of BMI on serum estradiol and bone turnover markers in postmenopausal women with hormone-sensitive early breast cancer treated with anastrozole.
Topics: Anastrozole; Aromatase Inhibitors; Body Mass Index; Bone and Bones; Breast Neoplasms; Collagen Type I; Estradiol; Female; Humans; Middle Aged; Neoplasms, Hormone-Dependent; Nitriles; Obesity; Overweight; Peptide Fragments; Peptides; Postmenopause; Procollagen; Receptors, Estrogen; Triazoles | 2014 |
Computational studies on the anastrozole and letrozole, effective chemotherapy drugs against breast cancer.
Topics: Anastrozole; Antineoplastic Agents; Breast Neoplasms; Carbon-13 Magnetic Resonance Spectroscopy; Computer Simulation; Female; Humans; Letrozole; Models, Molecular; Molecular Conformation; Nitriles; Proton Magnetic Resonance Spectroscopy; Static Electricity; Triazoles; Vibration | 2014 |
Breast cancer chemoprevention: little progress in practice?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Female; Humans; Nitriles; Triazoles | 2014 |
Predicting distant recurrence in receptor-positive breast cancer patients with limited clinicopathological risk: using the PAM50 Risk of Recurrence score in 1478 postmenopausal patients of the ABCSG-8 trial treated with adjuvant endocrine therapy alone.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Clinical Trials as Topic; Disease-Free Survival; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Postmenopause; Prognosis; Proportional Hazards Models; Receptor, ErbB-2; Retrospective Studies; Risk; Risk Assessment; Tamoxifen; Transcriptome; Treatment Outcome; Triazoles | 2014 |
Women commencing anastrozole, letrozole or tamoxifen for early breast cancer: the impact of comorbidity and demographics on initial choice.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Australia; Breast Neoplasms; Cohort Studies; Comorbidity; Female; Humans; Letrozole; Middle Aged; Neoplasm Staging; Nitriles; Postmenopause; Practice Guidelines as Topic; Premenopause; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles; Tumor Burden | 2014 |
Tumour grade on core biopsy and evidence of axillary involvement on ultrasound predicts response in elderly co-morbid patients treated with primary hormone therapy for oestrogen receptor positive breast carcinoma.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Axilla; Biopsy, Large-Core Needle; Breast Neoplasms; Female; Humans; Letrozole; Lymph Nodes; Lymphatic Metastasis; Middle Aged; Nitriles; Receptors, Estrogen; Retrospective Studies; Tamoxifen; Triazoles | 2015 |
Treatment of ovarian anaplastic ependymoma by an aromatase inhibitor.
Topics: Anastrozole; Aromatase Inhibitors; Ependymoma; Female; Humans; Middle Aged; Nitriles; Ovarian Neoplasms; Triazoles | 2014 |
Efficacy and safety of Trastuzumab added to standard treatments for HER2-positive metastatic breast cancer patients.
Topics: Anastrozole; Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Female; Humans; Letrozole; Meta-Analysis as Topic; Nitriles; Paclitaxel; Prognosis; Randomized Controlled Trials as Topic; Receptor, ErbB-2; Taxoids; Trastuzumab; Triazoles | 2013 |
Does obesity interfere with anastrozole treatment? Positive association between body mass index and anastrozole plasma levels.
Topics: Aged; Aged, 80 and over; Anastrozole; Androgens; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Chromatography, Liquid; Cross-Sectional Studies; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Follow-Up Studies; Humans; Middle Aged; Nitriles; Obesity; Postmenopause; Prognosis; Tandem Mass Spectrometry; Tissue Distribution; Triazoles | 2014 |
New trials highlight breast cancer therapy and prevention.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Nitriles; Postmenopause; Randomized Controlled Trials as Topic; Risk; Triazoles | 2014 |
Anastrozole may aid breast cancer prevention.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Nitriles; Triazoles | 2014 |
Relationship of body mass index with aromatisation and plasma and tissue oestrogen levels in postmenopausal breast cancer patients treated with aromatase inhibitors.
Topics: Aged; Anastrozole; Androgens; Aromatase; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Estradiol; Estrogens; Estrone; Female; Humans; Letrozole; Middle Aged; Nitriles; Outcome Assessment, Health Care; Postmenopause; Triazoles | 2014 |
Long-term outcome of neoadjuvant endocrine therapy with aromatase inhibitors in elderly women with hormone receptor-positive breast cancer.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Letrozole; Neoadjuvant Therapy; Neoplasm Grading; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Retrospective Studies; Survival Rate; Tamoxifen; Time Factors; Triazoles | 2014 |
Biomarker changes associated with the development of resistance to aromatase inhibitors (AIs) in estrogen receptor-positive breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Androstadienes; Aromatase Inhibitors; Biomarkers, Tumor; Breast Neoplasms; Drug Resistance, Neoplasm; Female; Humans; Insulin Receptor Substrate Proteins; Ki-67 Antigen; Letrozole; Middle Aged; Neoplasm Recurrence, Local; Nitriles; PTEN Phosphohydrolase; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Stathmin; Tamoxifen; Triazoles | 2014 |
Prevention: targeted therapy-anastrozole prevents breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Molecular Targeted Therapy; Nitriles; Postmenopause; Triazoles | 2014 |
Graphene oxide based magnetic nanocomposites for efficient treatment of breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Survival; Drug Carriers; Female; Graphite; Humans; Magnetite Nanoparticles; MCF-7 Cells; Nitriles; Oxides; Particle Size; Triazoles | 2014 |
The bone substudy of MA.27: does bone make a difference?
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Bone Density; Breast Neoplasms; Female; Humans; Neoplasms, Hormone-Dependent; Nitriles; Triazoles | 2014 |
Testosterone, anastrozole, factor V Leiden heterozygosity and osteonecrosis of the jaws.
Topics: Anastrozole; Bisphosphonate-Associated Osteonecrosis of the Jaw; Factor V; Humans; Male; Middle Aged; Nitriles; Osteonecrosis; Testosterone; Triazoles | 2014 |
[A case of postmenopausal breast cancer becoming HER2 positive after neoadjuvant hormone therapy].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Female; Humans; Mammography; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Postmenopause; Receptor, ErbB-2; Triazoles | 2014 |
Outcome analysis of aromatase inhibitor therapy to increase adult height in males with predicted short adult stature and/or rapid pubertal progress: a retrospective chart review.
Topics: Adolescent; Adult; Age Determination by Skeleton; Anastrozole; Aromatase Inhibitors; Body Height; Bone Development; Dwarfism; Growth Disorders; Humans; Male; Nitriles; Puberty; Retrospective Studies; Sexual Maturation; Treatment Outcome; Triazoles | 2014 |
Influence of aromatase inhibition on the bone-protective effects of testosterone.
Topics: Anabolic Agents; Anastrozole; Androgens; Animals; Aromatase; Aromatase Inhibitors; Heptanoates; Male; Muscle, Skeletal; Nitriles; Orchiectomy; Osteoporosis; Rats; Rats, Inbred F344; Testosterone; Trenbolone Acetate; Triazoles | 2014 |
[Effect of genistein combined with anastrozole on mammary tumors in ovariectomized rats].
Topics: 17-Hydroxysteroid Dehydrogenases; Anastrozole; Animals; Cell Line, Tumor; Cell Proliferation; Estradiol; Female; Genistein; Mammary Neoplasms, Experimental; Nitriles; Ovariectomy; Postmenopause; Rats; Rats, Sprague-Dawley; Triazoles | 2014 |
The effects of hormonotherapy administered concurrent radiotherapy and trastuzumab on cardiac toxicity in rats.
Topics: Anastrozole; Androstadienes; Animals; Antibodies, Monoclonal; Aromatase Inhibitors; Combined Modality Therapy; Drug Administration Schedule; Female; Heart; Humans; Letrozole; Nitriles; Radiotherapy; Rats; Rats, Wistar; Trastuzumab; Triazoles; Tumor Protein, Translationally-Controlled 1 | 2014 |
Effect of anastrozole on hormone levels in postmenopausal women with early breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Bone Density; Bone Remodeling; Breast Neoplasms; Dehydroepiandrosterone Sulfate; Estradiol; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Longitudinal Studies; Luteinizing Hormone; Middle Aged; Nitriles; Postmenopause; Sex Hormone-Binding Globulin; Single-Blind Method; Testosterone; Triazoles | 2015 |
Aromatase inhibition in relapsing low malignant potential serous tumours of the ovary.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Carcinoma, Ovarian Epithelial; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Glandular and Epithelial; Nitriles; Ovarian Neoplasms; Peritoneal Neoplasms; Receptors, Estrogen; Receptors, Progesterone; Remission Induction; Splenectomy; Splenic Neoplasms; Triazoles | 2014 |
A hard pill to swallow: a qualitative study of women's experiences of adjuvant endocrine therapy for breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Attitude to Health; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Letrozole; Medication Adherence; Middle Aged; Nitriles; Qualitative Research; Quality of Life; Tamoxifen; Triazoles | 2014 |
Another pill for breast cancer prevention.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles | 2014 |
Drug cuts breast cancer risk by more than half.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Health Promotion; Humans; Middle Aged; Nitriles; Postmenopause; Triazoles; Women's Health | 2014 |
Remission of metastatic primary mucinous carcinoma of the skin with anastrozole.
Topics: Adenocarcinoma, Mucinous; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Female; Head and Neck Neoplasms; Humans; Mohs Surgery; Neoplasm Recurrence, Local; Nitriles; Remission Induction; Scalp; Skin Neoplasms; Treatment Failure; Triazoles | 2014 |
Sex-dependent influence of endogenous estrogen in pulmonary hypertension.
Topics: Anastrozole; Animals; Aromatase Inhibitors; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Estrogens; Female; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Inbred C57BL; Nitriles; Polymerase Chain Reaction; Rats; Rats, Wistar; Sex Factors; Triazoles | 2014 |
Silk fibroin rods for sustained delivery of breast cancer therapeutics.
Topics: Anastrozole; Animals; Antineoplastic Agents; Biodegradation, Environmental; Breast Neoplasms; Drug Delivery Systems; Female; Fibroins; Kinetics; Microscopy, Electron, Scanning; Nitriles; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Time Factors; Triazoles | 2014 |
Gonadotrophin-independent precocious puberty associated with later diagnosis of testicular embryonal carcinoma.
Topics: Adolescent; Anastrozole; Androgens; Antineoplastic Agents, Hormonal; Carcinoma, Embryonal; Child; Chorionic Gonadotropin, beta Subunit, Human; Growth; Humans; Male; Nitriles; Orchiectomy; Puberty, Precocious; Testicular Neoplasms; Testis; Treatment Outcome; Triazoles | 2014 |
[Pulmonary metastasis from breast cancer 38 years after mastectomy; report of a case].
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Lung Neoplasms; Mastectomy; Nitriles; Time Factors; Tomography, X-Ray Computed; Triazoles | 2014 |
Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats.
Topics: Anastrozole; Androgen Antagonists; Androstenedione; Animals; Aromatase Inhibitors; Brain; Cognition Disorders; Estrone; Female; Flutamide; Maze Learning; Menopause; Nitriles; Ovariectomy; Rats, Inbred F344; Receptors, Androgen; Triazoles; Uterus | 2015 |
AR collaborates with ERα in aromatase inhibitor-resistant breast cancer.
Topics: Anastrozole; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; MCF-7 Cells; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Receptors, Androgen; Tamoxifen; Triazoles | 2014 |
Use of aromatase inhibitors in large cell calcifying sertoli cell tumors: effects on gynecomastia, growth velocity, and bone age.
Topics: AMP-Activated Protein Kinase Kinases; Anastrozole; Antineoplastic Agents; Aromatase Inhibitors; Bone Development; Calcinosis; Carney Complex; Child; Child, Preschool; Growth; Gynecomastia; Humans; Infant; Letrozole; Male; Nitriles; Peutz-Jeghers Syndrome; Protein Serine-Threonine Kinases; Sertoli Cell Tumor; Treatment Outcome; Triazoles | 2014 |
Case report: anti-hormonal therapy in the treatment of ductal carcinoma of the parotid gland.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Carcinoma, Ductal; Disease-Free Survival; Female; Humans; Neoplasm Metastasis; Nitriles; Parotid Neoplasms; Tamoxifen; Treatment Outcome; Triazoles | 2014 |
Arthralgia induced by endocrine treatment for breast cancer: A prospective study of serum levels of insulin like growth factor-I, its binding protein and oestrogens.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Arthralgia; Breast Neoplasms; Chemotherapy, Adjuvant; Estrogens; Female; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Letrozole; Middle Aged; Musculoskeletal Pain; Nitriles; Prospective Studies; Tamoxifen; Triazoles | 2014 |
Longitudinal trends in utilization of endocrine therapies for breast cancer: an international comparison.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Australia; Breast Neoplasms; Developed Countries; Drug Utilization Review; England; Female; France; Humans; Internationality; Letrozole; Longitudinal Studies; Netherlands; Nitriles; Scandinavian and Nordic Countries; Tamoxifen; Triazoles | 2015 |
Primary Hormonal Therapy for Elderly Breast Cancer Patients: Single Institution Experience.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Estradiol; Female; Fulvestrant; Humans; Letrozole; Nitriles; Receptors, Estrogen; Retrospective Studies; Spain; Tamoxifen; Treatment Outcome; Triazoles | 2015 |
Effects of modified Shu-Gan-Liang-Xue decoction combined with anastrozole on osteoblastic proliferation and differentiation of MC3T3-E1 cells.
Topics: Alkaline Phosphatase; Anastrozole; Animals; Calcification, Physiologic; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression; Humans; Mice; Nitriles; Osteoblasts; Osteocalcin; RNA, Messenger; Triazoles | 2015 |
Budget impact analysis of everolimus for the treatment of hormone receptor positive, human epidermal growth factor receptor-2 negative (HER2-) advanced breast cancer in Kazakhstan.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cost-Benefit Analysis; Disease Progression; Everolimus; Female; Humans; Kazakhstan; Letrozole; Nitriles; Postmenopause; Receptor, ErbB-2; Triazoles | 2015 |
Characterization of anastrozole effects, delivered by an intravaginal ring in cynomolgus monkeys.
Topics: Administration, Intravaginal; Anastrozole; Animals; Aromatase Inhibitors; Delayed-Action Preparations; Dose-Response Relationship, Drug; Down-Regulation; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Implants; Estradiol; Feasibility Studies; Female; Follicle Stimulating Hormone; Half-Life; Infusions, Intravenous; Macaca fascicularis; Menstrual Cycle; Metabolic Clearance Rate; Nitriles; Solubility; Triazoles | 2015 |
Steroidal and non-steroidal third-generation aromatase inhibitors induce pain-like symptoms via TRPA1.
Topics: Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Behavior, Animal; Calcium; Calcium Channels; Cysteine; HEK293 Cells; Humans; Inflammation; Letrozole; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Neuropeptides; Nitriles; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Steroids; Transient Receptor Potential Channels; Triazoles; TRPA1 Cation Channel; TRPC Cation Channels | 2014 |
No pain, no gain: a fallacy so far.
Topics: Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Musculoskeletal System; Nitriles; Triazoles; Vasomotor System | 2015 |
An unusual cause of jaundice in a patient with breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Fatty Liver; Female; Humans; Jaundice; Liver; Liver Function Tests; Middle Aged; Nitriles; Triazoles | 2014 |
Case records of the Massachusetts General Hospital. Case 1-2015. A 66-year-old woman with metastatic breast cancer after endocrine therapy.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Class I Phosphatidylinositol 3-Kinases; Diagnosis, Differential; Female; Humans; Lung Neoplasms; Lymph Nodes; Magnetic Resonance Imaging; Mastectomy, Segmental; Mutation; Nitriles; Phosphatidylinositol 3-Kinases; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Triazoles | 2015 |
[A case of hyoid bone metastasis from breast cancer].
Topics: Aged; Anastrozole; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Denosumab; Female; Humans; Lymphatic Metastasis; Nitriles; Triazoles | 2014 |
Antiproliferative effects of anastrozole on MCF-7 human breast cancer cells in vitro are significantly enhanced by combined treatment with testosterone undecanoate.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Breast Neoplasms; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Nitriles; Receptors, Androgen; Signal Transduction; Testosterone; Triazoles | 2015 |
Management of Premenopausal Women with Neoadjuvant Endocrine Therapy: A Single-Institution Experience.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Gonadotropin-Releasing Hormone; Humans; Letrozole; Middle Aged; Neoadjuvant Therapy; Nitriles; Premenopause; Receptors, Estrogen; Response Evaluation Criteria in Solid Tumors; Tamoxifen; Triazoles | 2015 |
Aromatase inhibitor (anastrozole) affects growth of endometrioma cells in culture.
Topics: Anastrozole; Aromatase Inhibitors; Cell Proliferation; Cells, Cultured; Endometriosis; Estradiol; Female; Humans; Nitriles; Testosterone; Triazoles | 2015 |
PEGylated liposomes of anastrozole for long-term treatment of breast cancer: in vitro and in vivo evaluation.
Topics: Anastrozole; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Liposomes; MCF-7 Cells; Nitriles; Particle Size; Polyethylene Glycols; Rats; Rats, Wistar; Structure-Activity Relationship; Surface Properties; Triazoles | 2016 |
The effect of estrogen synthesis inhibition on hippocampal memory.
Topics: Aged; Anastrozole; Estradiol; Female; Gyrus Cinguli; Hippocampus; Humans; Letrozole; Long-Term Potentiation; Longitudinal Studies; Magnetic Resonance Imaging; Memory; Memory, Short-Term; Middle Aged; Nitriles; Postmenopause; Prefrontal Cortex; Psychomotor Performance; Steroid Synthesis Inhibitors; Surveys and Questionnaires; Triazoles; Verbal Learning; Word Association Tests | 2015 |
Breast cancer risk reduction therapy: the low-hanging fruit.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Hyperplasia; Nitriles; Practice Patterns, Physicians'; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles | 2015 |
Solitary uterine metastasis of invasive lobular carcinoma after adjuvant endocrine therapy: a case report.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Lobular; Carrier Proteins; Combined Modality Therapy; Female; Glycoproteins; Humans; Leiomyoma; Membrane Transport Proteins; Middle Aged; Nitriles; Triazoles; Uterine Neoplasms | 2015 |
Patterns of change in cognitive function with anastrozole therapy.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Case-Control Studies; Chemotherapy, Adjuvant; Cognition; Cognition Disorders; Educational Status; Female; Humans; Longitudinal Studies; Memory; Middle Aged; Nitriles; Postmenopause; Triazoles | 2015 |
Identifying clinically relevant prognostic subgroups of postmenopausal women with node-positive hormone receptor-positive early-stage breast cancer treated with endocrine therapy: a combined analysis of ABCSG-8 and ATAC using the PAM50 risk of recurrence
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Humans; Lymph Nodes; Neoplasm Recurrence, Local; Neoplasm Staging; Nitriles; Postmenopause; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Risk Assessment; Tamoxifen; Triazoles | 2015 |
The introduction of generic aromatase inhibitors and treatment adherence among Medicare D enrollees.
Topics: Aged; Aged, 80 and over; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cohort Studies; Drug Costs; Drugs, Generic; Evaluation Studies as Topic; Female; Humans; Letrozole; Medicare; Medication Adherence; Nitriles; Non-Randomized Controlled Trials as Topic; Poverty; Triazoles; United States | 2015 |
Anastrozole is a dose-specific superovulator and favors implantation in rats: a prospective study.
Topics: Anastrozole; Animals; Dose-Response Relationship, Drug; Embryo Implantation; Female; Nitriles; Ovulation; Pregnancy; Rats; Rats, Wistar; Triazoles | 2016 |
Adjuvant treatments of breast cancer increase the risk of depressive disorders: A population-based study.
Topics: Adult; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Chemotherapy, Adjuvant; Depressive Disorder; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Letrozole; Middle Aged; Nitriles; Population Surveillance; Proportional Hazards Models; Retrospective Studies; Risk; Taiwan; Tamoxifen; Trastuzumab; Triazoles | 2015 |
Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer.
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Kelch-Like ECH-Associated Protein 1; Letrozole; MCF-7 Cells; Molecular Structure; NF-E2-Related Factor 2; Nitriles; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Triazoles; Ubiquitination | 2015 |
Multiple gene aberrations and breast cancer: lessons from super-responders.
Topics: Adult; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Disease-Free Survival; Everolimus; Female; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Middle Aged; Mutation; Neoplasm Proteins; Nitriles; Phosphatidylinositol 3-Kinases; TOR Serine-Threonine Kinases; Treatment Outcome; Triazoles | 2015 |
Marketed Drugs Can Inhibit Cytochrome P450 27A1, a Potential New Target for Breast Cancer Adjuvant Therapy.
Topics: Adjuvants, Pharmaceutic; Anastrozole; Anilides; Animals; Antifungal Agents; Antineoplastic Agents; Breast Neoplasms; Cholestanetriol 26-Monooxygenase; Dexmedetomidine; Enzyme Inhibitors; Fadrozole; Female; Hypnotics and Sedatives; Mice; Mice, Inbred C57BL; Nitriles; Protein Binding; Thiazoles; Tosyl Compounds; Triazoles | 2015 |
Healthcare professionals' preferences for surgery or primary endocrine therapy to treat older women with operable breast cancer.
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Attitude of Health Personnel; Breast Neoplasms; Female; Geriatrics; Humans; Letrozole; Mastectomy; Nitriles; Oncology Nursing; Patient Preference; Receptors, Estrogen; Surgeons; Surveys and Questionnaires; Tamoxifen; Triazoles; United Kingdom | 2015 |
A case of anastrazole-related drug-induced autoimmune hepatitis.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Chemical and Drug Induced Liver Injury; Female; Hepatitis, Autoimmune; Humans; Nitriles; Triazoles | 2014 |
Evaluation of response to hormone therapy in patients with measurable adult granulosa cell tumors of the ovary.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chemotherapy, Adjuvant; Disease Progression; Disease-Free Survival; Female; Goserelin; Granulosa Cell Tumor; Humans; Letrozole; Megestrol Acetate; Middle Aged; Nitriles; Ovarian Neoplasms; Ovariectomy; Radiotherapy, Adjuvant; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Salpingectomy; Tamoxifen; Triazoles | 2015 |
Picking the optimal endocrine adjuvant treatment for pre-menopausal women.
Topics: Age Factors; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Goserelin; Humans; Letrozole; Nitriles; Ovary; Premenopause; Tamoxifen; Triazoles | 2015 |
Neoadjuvant endocrine therapy: Patient selection, treatment duration and surrogate endpoints.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Humans; Ki-67 Antigen; Letrozole; Neoadjuvant Therapy; Neoplasm Staging; Nitriles; Patient Selection; Prognosis; Tamoxifen; Time Factors; Triazoles | 2015 |
Development and validation of a rapid LC-MS/MS method to quantify letrozole in human plasma and its application to therapeutic drug monitoring.
Topics: Anastrozole; Antineoplastic Agents; Chromatography, Liquid; Drug Monitoring; Humans; Letrozole; Limit of Detection; Nitriles; Tandem Mass Spectrometry; Triazoles | 2016 |
Insights into biology of luminal HER2 vs. enriched HER2 subtypes: Therapeutic implications.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Drug Resistance, Neoplasm; Female; Humans; Lapatinib; Letrozole; Molecular Imaging; Neoadjuvant Therapy; Nitriles; Precision Medicine; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Trastuzumab; Triazoles | 2015 |
Risk factors for joint symptoms in postmenopausal Japanese breast cancer patients treated with anastrozole: a prospective multicenter cohort study of patient-reported outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chemotherapy, Adjuvant; Female; Humans; Joint Diseases; Middle Aged; Neoplasm Staging; Nitriles; Patient Outcome Assessment; Postmenopause; Prognosis; Prospective Studies; Quality of Life; Risk Factors; Surveys and Questionnaires; Triazoles | 2016 |
Nanomedicine of anastrozole for breast cancer: Physicochemical evaluation, in vitro cytotoxicity on BT-549 and MCF-7 cell lines and preclinical study on rat model.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Drug Evaluation, Preclinical; Drug Stability; Female; Humans; MCF-7 Cells; Nanomedicine; Nanoparticles; Nitriles; Particle Size; Rats; Triazoles | 2015 |
Aromatase Inhibition and Capecitabine Combination as 1st or 2nd Line Treatment for Metastatic Breast Cancer - a Retrospective Analysis.
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Breast Neoplasms; Capecitabine; Diarrhea; Disease Progression; Disease-Free Survival; Fatigue; Female; Follow-Up Studies; Hand-Foot Syndrome; Humans; Letrozole; Middle Aged; Nitriles; Receptors, Estrogen; Receptors, Progesterone; Retreatment; Retrospective Studies; Survival Rate; Triazoles | 2015 |
Hypervitaminosis B12 As an Additional Prognostic Indicator in Elderly Adults with a Neoplastic Disease: Report of a Case and Review of the Literature.
Topics: Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Geriatric Assessment; Humans; Life Expectancy; Mammography; Neoplasm Staging; Nitriles; Predictive Value of Tests; Prognosis; Triazoles; Vitamin B 12 | 2015 |
Long-term survival in low-grade endometrial stromal sarcoma with childbirth and multidisciplinary treatment: a case report.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Biopsy; Endometrial Neoplasms; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Sarcoma, Endometrial Stromal; Survivors; Tomography, X-Ray Computed; Triazoles; Young Adult | 2015 |
The Effects of Adjuvant Endocrine Treatment on Serum Leptin, Serum Adiponectin and Body Composition in Patients with Breast Cancer: The Izmir Oncology Group (IZOG) Study.
Topics: Adiponectin; Adult; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Composition; Body Mass Index; Breast Neoplasms; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Leptin; Letrozole; Middle Aged; Nitriles; Tamoxifen; Triazoles | 2016 |
The impact of Anastrazole and Letrozole on the metabolic profile in an experimental animal model.
Topics: Anastrozole; Animals; Female; Letrozole; Lipid Metabolism; Liver; Nitriles; Rats; Rats, Wistar; Triazoles | 2015 |
Adjuvant Ovarian Suppression, High-dose Chemotherapy and Immunotherapy for Premenopausal Patients with High-risk Breast Cancer.
Topics: Adult; Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Aromatase Inhibitors; Bone Marrow Transplantation; Breast Neoplasms; Carboplatin; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease-Free Survival; Endpoint Determination; Etoposide; Female; Humans; Ifosfamide; Immunotherapy; Interleukin-2; Isotretinoin; Leuprolide; Nitriles; Premenopause; Receptors, Estrogen; Receptors, Progesterone; Triazoles; Triple Negative Breast Neoplasms | 2015 |
[Efficacies of aromatase inhibitors in the treatment of hormone dependent metastatic breast cancer in postmenopausal women: a report of 148 cases].
Topics: Anastrozole; Androstadienes; Aromatase Inhibitors; Breast Neoplasms; Disease-Free Survival; Female; Hormones; Humans; Letrozole; Neoplasm Metastasis; Nitriles; Postmenopause; Triazoles | 2015 |
Ginkgo biloba extract EGb 761-mediated inhibition of aromatase for the treatment of hormone-dependent breast cancer.
Topics: Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Agents, Phytogenic; Aromatase; Breast Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Ginkgo biloba; Humans; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Neoplasms, Experimental; Nitriles; Plant Extracts; RNA, Messenger; Triazoles | 2016 |
Effect of imatinib on growth of experimental endometriosis in rats.
Topics: Anastrozole; Angiogenesis Inhibitors; Animals; Aromatase Inhibitors; bcl-2-Associated X Protein; Cell Proliferation; Disease Models, Animal; Endometriosis; Endometrium; Female; Imatinib Mesylate; Nitriles; Ovarian Follicle; Peritoneal Diseases; Peritoneum; Proto-Oncogene Proteins c-kit; Rats; Transplantation, Autologous; Triazoles; Vascular Endothelial Growth Factor A | 2016 |
miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors.
Topics: Anastrozole; Animals; Antineoplastic Agents; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Estrogens; Female; Glycolysis; Hexokinase; Humans; Letrozole; MCF-7 Cells; Mice; Mice, Nude; MicroRNAs; Neoadjuvant Therapy; Nitriles; Phosphorylation; Receptors, Estrogen; Triazoles | 2016 |
[A Case of Locally Advanced Breast Cancer Treated with Modified Radical Mastectomy with Immediate Reconstruction Using a Tissue Expander after Endocrine Therapy].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Biopsy, Large-Core Needle; Breast Implants; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Humans; Mastectomy, Modified Radical; Middle Aged; Nitriles; Tissue Expansion Devices; Triazoles | 2015 |
Exemestane-induced radiation recall dermatitis and morbilliform rash.
Topics: Aged; Anastrozole; Androstadienes; Antineoplastic Agents; Aromatase Inhibitors; Arthralgia; Carcinoma, Ductal, Breast; Chemotherapy, Adjuvant; Drug Eruptions; Eosinophilia; Epidermis; Exanthema; Female; Humans; Nitriles; Radiodermatitis; Radiotherapy, Adjuvant; Triazoles; Withholding Treatment | 2016 |
Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene.
Topics: Anastrozole; Androgen Antagonists; Anilides; Aromatase Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Genetic Predisposition to Disease; Humans; Infant; Ketoconazole; Male; Mutation; Nitriles; Puberty, Precocious; Receptors, LH; Sequence Analysis, DNA; Testosterone; Tosyl Compounds; Triazoles | 2015 |
A global economic model to assess the cost-effectiveness of new treatments for advanced breast cancer in Canada.
Topics: Anastrozole; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Canada; Cost-Benefit Analysis; Disease Progression; Female; Health Services; Humans; Lapatinib; Letrozole; Markov Chains; Models, Econometric; Neoplasm Metastasis; Nitriles; Quality-Adjusted Life Years; Quinazolines; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Terminal Care; Trastuzumab; Triazoles | 2016 |
Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer.
Topics: AC133 Antigen; Anastrozole; Androstadienes; Animals; Antigens, CD; Antineoplastic Agents, Hormonal; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Cell Line, Tumor; Cell Self Renewal; Drug Resistance, Neoplasm; Estradiol; Female; Flow Cytometry; Fulvestrant; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; In Vitro Techniques; Interleukin-6; Letrozole; Leuprolide; MCF-7 Cells; Mice, Inbred NOD; Mice, SCID; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Nitriles; Oxidative Phosphorylation; Peptides; Real-Time Polymerase Chain Reaction; Receptor, Notch3; Receptors, Estrogen; Receptors, Notch; Signal Transduction; Tamoxifen; Triazoles | 2016 |
Long-Term Disease-Free Survival in a Young Patient With Hormone Receptor-Positive Breast Cancer and Oligometastatic Disease in the Brain.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Carmustine; Chemoradiotherapy; Craniotomy; Cyclophosphamide; Decanoic Acids; Disease-Free Survival; Doxorubicin; Female; Humans; Leuprolide; Nitriles; Paclitaxel; Polyesters; Radiosurgery; Receptors, Estrogen; Triazoles; Young Adult | 2016 |
The association between pre-treatment occupational skill level and mood and symptom burden in early-stage, postmenopausal breast cancer survivors during the first year of anastrozole therapy.
Topics: Affect; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cognition; Employment; Female; Humans; Middle Aged; Nitriles; Postmenopause; Self Report; Surveys and Questionnaires; Survivors; Triazoles | 2016 |
Analysis of 17β-estradiol (E2) role in the regulation of corpus luteum function in pregnant rats: Involvement of IGFBP5 in the E2-mediated actions.
Topics: Anastrozole; Androgen Antagonists; Animals; Aromatase Inhibitors; Cell Proliferation; Corpus Luteum; Estradiol; Female; Flutamide; Gene Expression; Gene Expression Profiling; Insulin-Like Growth Factor Binding Protein 5; Nitriles; Oligonucleotide Array Sequence Analysis; Pregnancy; Rats; Triazoles | 2016 |
A microsomal based method to detect aromatase activity in different brain regions of the rat using ultra performance liquid chromatography-mass spectrometry.
Topics: Amygdala; Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Brain Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Estradiol; Female; Hippocampus; Kinetics; Limit of Detection; Male; Microsomes; Nitriles; Ovary; Preoptic Area; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Testosterone; Triazoles | 2016 |
Cross-Stratification and Differential Risk by Breast Cancer Index and Recurrence Score in Women with Hormone Receptor-Positive Lymph Node-Negative Early-Stage Breast Cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Gene Expression Profiling; Health Status Indicators; Humans; Lymph Nodes; Neoplasm Recurrence, Local; Nitriles; Prognosis; Receptors, Estrogen; Receptors, Progesterone; Retrospective Studies; Risk Factors; Tamoxifen; Triazoles | 2016 |
Aromatase inhibitors decrease radiation-induced lung fibrosis: Results of an experimental study.
Topics: Anastrozole; Androstadienes; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Chemotherapy, Adjuvant; Female; Letrozole; Nitriles; Pulmonary Fibrosis; Radiation Injuries, Experimental; Radiotherapy; Rats; Rats, Wistar; Tamoxifen; Triazoles | 2016 |
Treatment with aromatase inhibitors stimulates the expression of epidermal growth factor receptor-1 and neuregulin 1 in ER positive/HER-2/neu non-amplified primary breast cancers.
Topics: Anastrozole; Aromatase Inhibitors; Breast Neoplasms; DNA Mutational Analysis; Drug Administration Schedule; ErbB Receptors; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Letrozole; Mutation; Neuregulin-1; Nitriles; Receptor, ErbB-2; RNA, Messenger; Treatment Outcome; Triazoles | 2017 |
Hypercalcemic crisis associated with anastrozole use in a patient with breast cancer and primary hyperparathyroidism.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Carcinoma In Situ; Breast Neoplasms; Calcium; Female; Humans; Hypercalcemia; Hyperparathyroidism; Middle Aged; Nitriles; Parathyroid Hormone; Parathyroidectomy; Treatment Outcome; Triazoles | 2016 |
Comparison of EndoPredict and EPclin With Oncotype DX Recurrence Score for Prediction of Risk of Distant Recurrence After Endocrine Therapy.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease-Free Survival; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Likelihood Functions; Lymph Nodes; Lymphatic Metastasis; Nitriles; Predictive Value of Tests; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Risk Assessment; Tamoxifen; Triazoles; Tumor Burden | 2016 |
Multiparametric Genomic Assays for Breast Cancer: Time for the Next Generation?
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Biological Assay; Breast Neoplasms; Disease-Free Survival; Female; Homeodomain Proteins; Humans; Nitriles; Postmenopause; Prognosis; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Interleukin-17; Receptors, Progesterone; Tamoxifen; Triazoles | 2016 |
Anastrozole-induced subacute cutaneous lupus erythematosus.
Topics: Aged; Anastrozole; Antibodies, Antinuclear; Arm; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Lupus Erythematosus, Cutaneous; Nitriles; Thorax; Triazoles | 2016 |
Fractional microablative CO2 laser for vulvovaginal atrophy in women treated with chemotherapy and/or hormonal therapy for breast cancer: a retrospective study.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Breast Neoplasms; Female; Humans; Lasers, Gas; Middle Aged; Nitriles; Retrospective Studies; Surveys and Questionnaires; Tamoxifen; Treatment Outcome; Triazoles; Vagina; Vaginal Diseases; Vulva | 2016 |
Polymorphisms in ABCB1 and CYP19A1 genes affect anastrozole plasma concentrations and clinical outcomes in postmenopausal breast cancer patients.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Arthralgia; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Nitriles; Polymorphism, Single Nucleotide; Postmenopause; Protective Factors; Proto-Oncogene Proteins; Risk Factors; Treatment Outcome; Triazoles | 2017 |
Enhancing Endocrine Therapy Combination Strategies for the Treatment of Postmenopausal HR+/HER2- Advanced Breast Cancer.
Topics: Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Circulating Tumor DNA; Disease-Free Survival; Estradiol; Female; Fulvestrant; Humans; Letrozole; Mutation; Neoplastic Cells, Circulating; Nitriles; Nuclear Proteins; Piperazines; Postmenopause; Pyridines; Receptor, ErbB-2; Receptors, Estrogen; Transcription Factors; Triazoles | 2017 |
Response to Anastrozole Treatment in a Case with Peutz-Jeghers Syndrome and a Large Cell Calcifying Sertoli Cell Tumor.
Topics: Anastrozole; Aromatase Inhibitors; Child; Gynecomastia; Humans; Male; Nitriles; Peutz-Jeghers Syndrome; Sertoli Cell Tumor; Testicular Neoplasms; Treatment Outcome; Triazoles | 2017 |
Mechanism of Bushen Jianpi decoction in preventing and treating osteoporosis caused by aromatase inhibitors in breast cancer treatment.
Topics: Alendronate; Alkaline Phosphatase; Anastrozole; Animals; Aromatase Inhibitors; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Disease Models, Animal; Drugs, Chinese Herbal; Female; Mice, Inbred BALB C; Nitriles; Osteoporosis; Ovariectomy; Triazoles | 2017 |
Abemaciclib Shows Promise for Early Breast Cancer.
Topics: Aminopyridines; Anastrozole; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Breast Neoplasms; Clinical Trials, Phase II as Topic; Disease-Free Survival; Female; Humans; Ki-67 Antigen; Nitriles; Receptor, ErbB-2; Survival Analysis; Treatment Outcome; Triazoles | 2017 |
Associations between pathologic tumor features and preadjuvant therapy cognitive performance in women diagnosed with breast cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Cognitive Dysfunction; Female; Humans; Middle Aged; Neuropsychological Tests; Nitriles; Prognosis; Receptor, ErbB-2; Triazoles | 2017 |
Growth Hormone With Aromatase Inhibitor May Improve Height in CYP11B1 Congenital Adrenal Hyperplasia.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Anastrozole; Aromatase Inhibitors; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Male; Nitriles; Triazoles | 2017 |
Letrozole not superior to anastrozole for early breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Female; Humans; Letrozole; Nitriles; Prognosis; Triazoles | 2017 |
Estrone and Estradiol Levels in Breast Cancer Patients Using Anastrozole Are Not Related to Body Mass Index.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Body Mass Index; Breast Neoplasms; Cohort Studies; Estradiol; Estrone; Female; Humans; Middle Aged; Nitriles; Triazoles | 2017 |
Hormonal Maintenance Therapy for Women With Low-Grade Serous Cancer of the Ovary or Peritoneum.
Topics: Adult; Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Cytoreduction Surgical Procedures; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Letrozole; Leuprolide; Maintenance Chemotherapy; Medroxyprogesterone Acetate; Middle Aged; Neoplasm Grading; Neoplasm Staging; Neoplasms, Cystic, Mucinous, and Serous; Nitriles; Ovarian Neoplasms; Peritoneal Neoplasms; Platinum Compounds; Survival Rate; Tamoxifen; Triazoles; Watchful Waiting; Young Adult | 2017 |
Ki-67 antigen expression in the mammary epithelium of female rats in persistent estrus treated with anastrozole.
Topics: Anastrozole; Animals; Cell Proliferation; Epithelium; Estrus; Female; Ki-67 Antigen; Mammary Glands, Animal; Nitriles; Rats; Rats, Wistar; Testosterone; Triazoles | 2017 |
High Initiation of Adjuvant Hormonal Therapy Among Uninsured Stages I-III Breast Cancer Patients Treated in a Safety-Net Healthcare System.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Chemotherapy, Adjuvant; Ethnicity; Female; Humans; Insurance, Health; Medicaid; Medically Uninsured; Neoplasm Staging; Nitriles; Safety-net Providers; Tamoxifen; Treatment Outcome; Triazoles; United States | 2017 |
Can we use gonadotropin plasma concentration as surrogate marker for BMI-related incomplete estrogen suppression in breast cancer patients receiving anastrozole?
Topics: Aged; Aged, 80 and over; Anastrozole; Aromatase Inhibitors; Biomarkers; Body Mass Index; Breast Neoplasms; Estrogens; Female; Gonadotropins; Humans; Middle Aged; Neoplasm Staging; Nitriles; Obesity; Postmenopause; Prognosis; Triazoles | 2017 |
Melasma treatment: A novel approach using a topical agent that contains an anti-estrogen and a vascular endothelial growth factor inhibitor.
Topics: Administration, Topical; Anastrozole; Androstadienes; Aromatase Inhibitors; Estrogens; Female; Genetic Predisposition to Disease; Humans; Hyperpigmentation; Letrozole; Male; Melanosis; Neovascularization, Pathologic; Nitriles; Pregnancy; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Triazoles; Ultraviolet Rays; Vascular Endothelial Growth Factor A | 2017 |
MAMMARY GLAND ADENOCARCINOMA IN A MALE BORNEAN ORANGUTAN (PONGO PYGMAEUS).
Topics: Adenocarcinoma; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Ape Diseases; Male; Mammary Neoplasms, Animal; Neoplasms, Hormone-Dependent; Nitriles; Pongo pygmaeus; Tamoxifen; Triazoles | 2017 |
Cytotoxicity anticancer activities of anastrozole against breast, liver hepatocellular, and prostate cancer cells.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Apoptosis; Aromatase; Aromatase Inhibitors; Cell Membrane Permeability; Cell Survival; Cytochromes c; Doxorubicin; Hep G2 Cells; Humans; MCF-7 Cells; Mitochondrial Membranes; Nitriles; Triazoles | 2017 |
A novel long-acting biodegradable depot formulation of anastrozole for breast cancer therapy.
Topics: Absorbable Implants; Anastrozole; Animals; Breast Neoplasms; Drug Implants; Female; Humans; Lactic Acid; Nitriles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Triazoles | 2017 |
Hydroxychloroquine toxicity and aromatase inhibitors.
Topics: Anastrozole; Aromatase Inhibitors; Dermatologic Agents; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Middle Aged; Nitriles; Retinal Diseases; Triazoles | 2017 |
Identification of endocrine disrupting chemicals acting on human aromatase.
Topics: Anastrozole; Aromatase; Aromatase Inhibitors; Benzhydryl Compounds; Biological Assay; Endocrine Disruptors; Enzyme-Linked Immunosorbent Assay; Estrone; Gene Expression; Humans; Ketoconazole; Ligands; NADP; Nicotine; Nitriles; Phenols; Protein Binding; Recombinant Proteins; Resveratrol; Sildenafil Citrate; Small Molecule Libraries; Stilbenes; Triazoles | 2018 |
Different patterns in the risk of newly developed fatty liver and lipid changes with tamoxifen versus aromatase inhibitors in postmenopausal women with early breast cancer: A propensity score-matched cohort study.
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Chemotherapy, Adjuvant; Fatty Liver; Female; Humans; Incidence; Letrozole; Lipids; Middle Aged; Nitriles; Propensity Score; Retrospective Studies; Tamoxifen; Triazoles | 2017 |
Cost-effectiveness analysis of fulvestrant versus anastrozole as first-line treatment for hormone receptor-positive advanced breast cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; China; Cost-Benefit Analysis; Drug Costs; Estradiol; Female; Fulvestrant; Humans; Markov Chains; Nitriles; Quality-Adjusted Life Years; Receptors, Estrogen; Receptors, Progesterone; Triazoles | 2017 |
Anastrozole-induced Autoimmune Hepatitis: A Rare Complication of Breast Cancer Therapy.
Topics: Aged; Anastrozole; Aromatase Inhibitors; Biopsy; Breast Neoplasms; Female; Hepatitis, Autoimmune; Humans; Liver; Neoplasm Staging; Nitriles; Triazoles | 2017 |
Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without compromising survival?
Topics: Adult; Aged; Anastrozole; Antineoplastic Agents; Chemotherapy, Adjuvant; Combined Modality Therapy; Cystadenocarcinoma, Serous; Cytoreduction Surgical Procedures; Female; Humans; Letrozole; Medical Overuse; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Ovarian Neoplasms; Retrospective Studies; Survival Analysis; Tamoxifen; Triazoles | 2017 |
Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects.
Topics: Anastrozole; Animals; Bone Morphogenetic Protein Receptors, Type II; Disease Models, Animal; Echocardiography; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Hemodynamics; Humans; Hypertension, Pulmonary; Insulin Resistance; Lung; Mice; Mice, Knockout; Mutation; Nitriles; Signal Transduction; Tamoxifen; Triazoles | 2017 |
Relevance of Spatial Heterogeneity of Immune Infiltration for Predicting Risk of Recurrence After Endocrine Therapy of ER+ Breast Cancer.
Topics: Aged; Anastrozole; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Disease-Free Survival; Female; Humans; Lymphocyte Count; Lymphocytes, Tumor-Infiltrating; Middle Aged; Neoplasm Recurrence, Local; Nitriles; Receptors, Estrogen; Risk Factors; Tamoxifen; Triazoles | 2018 |
Comparative pharmacokinetics study of anastrozole after single administration and combination with celecoxib.
Topics: Anastrozole; Animals; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Chromatography, Liquid; Cyclooxygenase 2 Inhibitors; Female; Limit of Detection; Nitriles; Rats, Sprague-Dawley; Reproducibility of Results; Tandem Mass Spectrometry; Triazoles | 2018 |
Working at the membrane interface: Ligand-induced changes in dynamic conformation and oligomeric structure in human aromatase.
Topics: Anastrozole; Aromatase; Humans; Ligands; Molecular Dynamics Simulation; Nitriles; Protein Structure, Quaternary; Triazoles | 2018 |
Isolated Retinal Metastasis From Breast Cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma, Ductal, Breast; Combined Modality Therapy; Female; Humans; Middle Aged; Nitriles; Radiosurgery; Receptors, Estrogen; Receptors, Progesterone; Retinal Neoplasms; Triazoles | 2017 |
Effect of aromatase inhibitors on learning and memory and modulation of hippocampal dickkopf-1 and sclerostin in female mice.
Topics: Adaptor Proteins, Signal Transducing; Anastrozole; Androstadienes; Animals; Aromatase Inhibitors; Cognition; Female; Glycoproteins; Hippocampus; Intercellular Signaling Peptides and Proteins; Letrozole; Maze Learning; Memory; Mice; Nitriles; Triazoles; Wnt Signaling Pathway | 2017 |
Preparation of anastrozole loaded PEG-PLA nanoparticles: evaluation of apoptotic response of breast cancer cell lines.
Topics: Anastrozole; Apoptosis; Aromatase Inhibitors; Breast Neoplasms; Cell Survival; Drug Delivery Systems; Female; Gene Expression Regulation, Neoplastic; Half-Life; Humans; MCF-7 Cells; Mitogen-Activated Protein Kinase 3; Myeloid Cell Leukemia Sequence 1 Protein; Nanoparticles; Nitriles; Particle Size; Polyesters; Polyethylene Glycols; Proto-Oncogene Proteins c-myc; Solubility; Triazoles | 2018 |
[A Case of Breast Cancer with Local Recurrence in the Reconstructed Breast Tissue].
Topics: Adult; Anastrozole; Breast Neoplasms; Female; Gonadotropin-Releasing Hormone; Hormone Replacement Therapy; Humans; Mammaplasty; Mastectomy; Multimodal Imaging; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Nitriles; Treatment Outcome; Triazoles | 2017 |
[A Case of Stage IV Breast Cancer with Extensive Metastasis Successfully Treated with S-1 plus Anastrozole Therapy].
Topics: Aged; Anastrozole; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Breast Neoplasms; Drug Combinations; Female; Humans; Lymphatic Metastasis; Nitriles; Oxonic Acid; Tegafur; Triazoles | 2017 |
Correlation of Serum Estradiol and Duration of Anastrazole Therapy with Treatment Related Adverse Effects Among Postmenopausal Breast Cancer Women: A Cross-sectional Study.
Topics: Aged; Anastrozole; Breast Neoplasms; Cross-Sectional Studies; Estradiol; Female; Hot Flashes; Humans; Middle Aged; Nitriles; Postmenopause; Quality of Life; Triazoles | 2017 |
Beneficial role of biochanin A on cutaneous and renal tissues of ovariectomized rats treated with anastrozole.
Topics: Acute Kidney Injury; Anastrozole; Animals; Antineoplastic Agents, Hormonal; Antioxidants; Cytokines; Female; Genistein; Kidney; Nitriles; Ovariectomy; Rats; Rats, Wistar; Skin; Triazoles | 2018 |
RE: "Cost-effectiveness analysis of fulvestrant versus anastrozole as first-line treatment for hormone receptor-positive advanced breast cancer," by Ding H., et al.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cost-Benefit Analysis; Estradiol; Fulvestrant; Humans; Nitriles; Postmenopause; Receptors, Estrogen; Triazoles | 2018 |
A Case of Psoriasis Complicated by Breast Cancer after Systemic Treatments Including Biologics.
Topics: Aged; Anastrozole; Antineoplastic Agents, Hormonal; Biological Products; Breast Neoplasms; Female; Humans; Immunosuppressive Agents; Nitriles; Psoriasis; Triazoles | 2018 |
[Determination of anaprazole in human plasma by LC-MS/MS in pharmacokinetic study].
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Area Under Curve; Chromatography, Liquid; Diet, High-Fat; Humans; Nitriles; Plasma; Reproducibility of Results; Tablets, Enteric-Coated; Tandem Mass Spectrometry; Triazoles | 2016 |
[Evaluation of Patient Adherence to Anastrozole Therapy for Breast Cancer].
Topics: Aged; Aged, 80 and over; Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Disease Progression; Humans; Middle Aged; Nitriles; Patient Compliance; Retrospective Studies; Triazoles | 2018 |
Palliative treatment of endometrial cancer: what is the role of anastrozole in elderly women?
Topics: Aged; Aged, 80 and over; Anastrozole; Endometrial Neoplasms; Female; Humans; Nitriles; Palliative Care; Pilot Projects; Quality of Life; Tamoxifen; Triazoles | 2021 |
Combination Vistusertib and Anastrozole Shows Benefit in Endometrial Cancer.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Benzamides; Breast Neoplasms; Endometrial Neoplasms; Female; Humans; Morpholines; Nitriles; Pyrimidines; Triazoles | 2022 |
Anastrozole and related glucuronic acid conjugate are electrophilic species.
Topics: Anastrozole; Animals; Breast Neoplasms; Chemical and Drug Induced Liver Injury; Female; Glucuronic Acid; Humans; Nitriles; Rats; Triazoles | 2022 |
Ribosome biogenesis-based predictive biomarkers in endocrine therapy (Anastrozole) combined with mTOR inhibitor (Vistusertib) in endometrial cancer: translational study from the VICTORIA trial in collaboration with the GINECO group.
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers; Breast Neoplasms; Endometrial Neoplasms; Female; Humans; Nitriles; Ribosomes; TOR Serine-Threonine Kinases; Triazoles | 2023 |
Effects of
Topics: Anastrozole; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Estradiol; Female; Fulvestrant; Genotype; Humans; Nitriles; Triazoles | 2023 |
Breast Tumor Cells Evade the Cytotoxic Action of Anastrozole, Aspirin, and Clopidogrel Cocktail.
Topics: Anastrozole; Animals; Antineoplastic Agents; Aspirin; Breast Neoplasms; Clopidogrel; Female; Humans; Mammary Neoplasms, Animal; Nitriles; Tamoxifen; Triazoles | 2023 |