Page last updated: 2024-08-22

anabaseine and anabasine

anabaseine has been researched along with anabasine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (14.81)18.2507
2000's10 (37.04)29.6817
2010's11 (40.74)24.3611
2020's2 (7.41)2.80

Authors

AuthorsStudies
Curtis, MA; Lin, SX; Sperry, J1
Buxton, ST; Crooks, PA; Deo, N; Dwoskin, LP; Ravard, A; Teng, L1
de Fiebre, CM; Henry, JC; Kem, WR; Meyer, EM; Muraskin, SI; Papke, RL1
Giacobini, E; Kem, WR; Summers, KL1
Kem, WR; Lingle, CJ; Mahnir, VM; Papke, RL1
Frye, TF; Hamilton, ME; Harris, MC; Kem, WR; Machu, TK; Shanklin, CL; Soti, FS; Sun, H; Tenner, TE1
Ikeda, I; Ozoe, Y; Sultana, I1
Horenstein, NA; Kem, WR; McCormack, TJ; Papke, JK; Papke, RL; Stokes, C1
Kem, WR; Machu, TK; Soti, FS; White, NA; Zhang, R1
Ho, KY; Kem, WR; Soti, FS; Talley, TT; Taylor, P; Tor, Y; Yalda, S1
Castedo, L; De la Fuente, J; Quezada, E; Sobarzo-Sánchez, E1
Bai, A; Guo, Y; Lu, N1
Horenstein, NA; Kem, WR; López-Hernández, GY; Papke, RL; Soti, F1
Arias, HR; Blanton, MP; Kem, WR; Macdougall, K; Soti, F; Xing, H1
Bourne, Y; Conrod, S; Hibbs, RE; Kem, WR; Marchot, P; Shi, J; Sulzenbacher, G; Talley, TT; Taylor, P1
Katritzky, AR; Kem, WR; LeFrancois, S; Radzvilovits, M; Slavov, SH; Soti, F; Stoyanova-Slavova, IB1
Bruyneel, B; de Esch, IJ; de Kloe, GE; de Vlieger, JS; Irth, H; Kool, J; Leurs, R; Lingeman, H; Retra, K; Smit, AB; van Elk, R; Wijtmans, M1
Caldwell, WS; Chewning, J; Hammond, PS; Hauser, TA; Kombo, DC; Mazurov, A; Tallapragada, K; Talley, TT; Taylor, P; Vasquez-Valdivieso, M; Yohannes, D1
Caldwell, WS; Chewning, J; Hammond, PS; Hauser, TA; Kombo, DC; Mazurov, AA; Speake, J; Tallapragada, K; Yohannes, D1
Horenstein, NA; Papke, RL; Stokes, C; Wang, J1
Horenstein, NA; Isaacson, MD; Kem, WR; Papke, RL; Stokes, C1
Dallanoce, C; De Amici, M; Fasoli, F; Fucile, S; Gotti, C; Grazioso, G; Matera, C; Pomè, DY; Quadri, M; Sciaccaluga, M1
Cook, D; Green, BT; Kem, WR; Lee, ST; Welch, KD1
Jiang, T; Ma, Q; Tabassum, N; Wu, G; Yu, R1
Cook, D; Green, BT; Keele, JW; Kem, WR; Lee, ST; Pfister, JA; Welch, KD1
Andrud, K; Bloom, L; Gabrielsen, B; Green, BT; Kem, W; Lee, S; Lindstrom, J; Mahnir, V; Xing, H1
Johnson, JV; Junoy, J; Kem, WR; Rocca, JR1

Reviews

1 review(s) available for anabaseine and anabasine

ArticleYear
Pyridine alkaloids with activity in the central nervous system.
    Bioorganic & medicinal chemistry, 2020, 12-15, Volume: 28, Issue:24

    Topics: Alkaloids; Amphibians; Animals; Bacteria; Central Nervous System Diseases; Fungi; Nicotine; Plants; Pyridines; Receptors, Nicotinic

2020

Other Studies

26 other study(ies) available for anabaseine and anabasine

ArticleYear
Minor alkaloids of tobacco release [3H]dopamine from superfused rat striatal slices.
    European journal of pharmacology, 1995, Mar-24, Volume: 276, Issue:1-2

    Topics: Anabasine; Animals; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Nicotine; Rats; Rats, Sprague-Dawley

1995
Characterization of a series of anabaseine-derived compounds reveals that the 3-(4)-dimethylaminocinnamylidine derivative is a selective agonist at neuronal nicotinic alpha 7/125I-alpha-bungarotoxin receptor subtypes.
    Molecular pharmacology, 1995, Volume: 47, Issue:1

    Topics: Alkaloids; Anabasine; Animals; Azocines; Bungarotoxins; Iodine Radioisotopes; Neurons; Nicotinic Agonists; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; Xenopus

1995
Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex.
    Japanese journal of pharmacology, 1997, Volume: 74, Issue:2

    Topics: Acetylcholine; Anabasine; Animals; Benzylidene Compounds; Cerebral Cortex; Dopamine; Male; Mecamylamine; Microdialysis; Neurotransmitter Agents; Nicotinic Agonists; Nicotinic Antagonists; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin

1997
Anabaseine is a potent agonist on muscle and neuronal alpha-bungarotoxin-sensitive nicotinic receptors.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:3

    Topics: Anabasine; Animals; Brain; Bungarotoxins; Injections, Intraventricular; Mice; Muscles; Neuromuscular Junction; Nicotinic Agonists; Radioligand Assay; Rana pipiens; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Torpedo; Xenopus

1997
Benzylidene analogs of anabaseine display partial agonist and antagonist properties at the mouse 5-hydroxytryptamine(3A) receptor.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3

    Topics: Anabasine; Animals; Benzylidene Compounds; Binding Sites; Electrophysiology; Nicotinic Agonists; Oocytes; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Xenopus laevis

2001
Structure-activity relationships of benzylidene anabaseines in nicotinic acetylcholine receptors of cockroach nerve cords.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:9

    Topics: Anabasine; Animals; Benzylidene Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cockroaches; Dose-Response Relationship, Drug; Insecticides; Mortality; Nervous System; Nicotinic Agonists; Plants; Pyridines; Quantitative Structure-Activity Relationship; Radioligand Assay; Receptors, Nicotinic; Regression Analysis

2002
The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors.
    Molecular pharmacology, 2004, Volume: 66, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Benzylidene Compounds; Binding Sites; Humans; Models, Molecular; Nicotinic Agonists; Protein Conformation; Pyridines; Rats; Receptors, Nicotinic; Species Specificity; Structure-Activity Relationship

2004
N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:3

    Topics: Anabasine; Animals; Benzylidene Compounds; Cloning, Molecular; Humans; Mice; Molecular Structure; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Xenopus laevis

2006
Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions.
    Biochemistry, 2006, Jul-25, Volume: 45, Issue:29

    Topics: Anabasine; Animals; Aplysia; Benzylidene Compounds; Bulinus; Carrier Proteins; Hydrogen-Ion Concentration; Ligands; Lymnaea; Receptors, Nicotinic; Spectrometry, Fluorescence

2006
Complete assignments 1H and 13C NMR spectral data of four anabaseine derivatives.
    Magnetic resonance in chemistry : MRC, 2006, Volume: 44, Issue:12

    Topics: Anabasine; Carbon Isotopes; Hydrogen; Isoquinolines; Magnetic Resonance Spectroscopy; Molecular Structure; Pyridines

2006
The effect of the cholinergic anti-inflammatory pathway on experimental colitis.
    Scandinavian journal of immunology, 2007, Volume: 66, Issue:5

    Topics: Anabasine; Animals; Blotting, Western; Chlorisondamine; Cholinergic Agonists; Colitis; Disease Models, Animal; Inflammation; Male; Mice; NF-kappa B; Nicotinic Antagonists; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2007
Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:2

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Benzylidene Compounds; Dose-Response Relationship, Drug; Female; Humans; Nicotine; Nicotinic Agonists; Oocytes; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Transfection; Xenopus laevis

2009
Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors.
    British journal of pharmacology, 2009, Volume: 157, Issue:2

    Topics: Allosteric Site; Anabasine; Animals; Benzylidene Compounds; Cells, Cultured; Humans; Muscles; Nicotinic Agonists; Radioligand Assay; Receptors, Nicotinic; Torpedo

2009
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor.
    The EMBO journal, 2009, Oct-07, Volume: 28, Issue:19

    Topics: Acetylcholine; Anabasine; Animals; Aplysia; Benzylidene Compounds; Carrier Proteins; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Indoles; Models, Molecular; Nicotinic Agonists; Protein Binding; Protein Conformation; Pyridines; Tropisetron

2009
A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Aplysia; Brain; Carrier Proteins; Computer Simulation; Models, Molecular; Molecular Conformation; Nicotinic Antagonists; Protein Binding; Quantitative Structure-Activity Relationship; Rats; Receptors, Nicotinic

2010
Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification.
    Journal of medicinal chemistry, 2010, Jun-24, Volume: 53, Issue:12

    Topics: Anabasine; Binding Sites; Carrier Proteins; Chromatography, Liquid; Drug Discovery; Flow Injection Analysis; Fluorometry; Ligands; Mass Spectrometry; Protein Binding; Radioligand Assay; Reproducibility of Results

2010
Docking studies of benzylidene anabaseine interactions with α7 nicotinic acetylcholine receptor (nAChR) and acetylcholine binding proteins (AChBPs): application to the design of related α7 selective ligands.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Benzylidene Compounds; Carrier Proteins; Drug Design; Hydrogen Bonding; Ligands; Models, Molecular; Protein Conformation; Rats; Receptors, Nicotinic; Substrate Specificity

2011
Discovery of novel α7 nicotinic acetylcholine receptor ligands via pharmacophoric and docking studies of benzylidene anabaseine analogs.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Benzylidene Compounds; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Structure; Receptors, Nicotinic; Stereoisomerism; Structure-Activity Relationship

2012
Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor.
    The Journal of biological chemistry, 2012, Jun-22, Volume: 287, Issue:26

    Topics: Allosteric Site; alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Cloning, Molecular; Cysteine; Dose-Response Relationship, Drug; Electrophysiology; Humans; Hydrogen Bonding; Isoxazoles; Ligands; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Phenylurea Compounds; Protein Conformation; Receptors, Nicotinic

2012
Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines.
    Biochemical pharmacology, 2013, Mar-15, Volume: 85, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Animals; Benzylidene Compounds; DNA, Complementary; Humans; Ligands; Models, Molecular; Protein Binding; Protein Conformation; Receptors, Nicotinic; Xenopus laevis

2013
Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Anabasine; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Pyridines; Receptors, Nicotinic; Structure-Activity Relationship

2016
Activation and Desensitization of Peripheral Muscle and Neuronal Nicotinic Acetylcholine Receptors by Selected, Naturally-Occurring Pyridine Alkaloids.
    Toxins, 2016, 07-04, Volume: 8, Issue:7

    Topics: Anabasine; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Membrane Potentials; Muscle Cells; Neurons; Nicotine; Nicotinic Agonists; Pyridines; Receptors, Nicotinic; Risk Assessment; Teratogens; Time Factors

2016
Exploring the binding energy profiles of full agonists, partial agonists, and antagonists of the α7 nicotinic acetylcholine receptor.
    Journal of molecular modeling, 2017, Volume: 23, Issue:9

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Anabasine; Benzylidene Compounds; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Humans; Indoles; Ligands; Lobeline; Molecular Docking Simulation; Nicotinic Agonists; Nicotinic Antagonists; Protein Binding; Pyridines; Strychnine; Tropisetron; Tubocurarine

2017
Complete inhibition of fetal movement in the day 40 pregnant goat model by the piperidine alkaloid anabasine but not related alkaloids.
    Toxicon : official journal of the International Society on Toxinology, 2018, Mar-15, Volume: 144

    Topics: Alkaloids; Anabasine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Female; Fetal Movement; Goats; Models, Animal; Pregnancy; Pyridines

2018
Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine.
    Marine drugs, 2019, Oct-29, Volume: 17, Issue:11

    Topics: Anabasine; Animals; Binding Sites; Brain; Cell Line; Humans; Nicotinic Agonists; Rats; Receptors, GABA; Receptors, Nicotinic; Structure-Activity Relationship

2019
Discovery of the Nicotinic Receptor Toxin Anabaseine in a
    Toxins, 2023, 01-05, Volume: 15, Issue:1

    Topics: Anabasine; Animals; Nicotinic Agonists; Receptors, Nicotinic; Toxins, Biological

2023