amyloid-beta-peptides and tris(2-pyridylmethyl)amine

amyloid-beta-peptides has been researched along with tris(2-pyridylmethyl)amine* in 1 studies

Other Studies

1 other study(ies) available for amyloid-beta-peptides and tris(2-pyridylmethyl)amine

Article	Year
A Novel Tetradentate Ruthenium(II) Complex Containing Tris(2- Pyridylmethyl)amine (tpa) As An Inhibitor Of Beta-amyloid Fibrillation. Current Alzheimer research, 2015, Volume: 12, Issue:5 We report herein the synthesis and application of a novel tetradentate ruthenium(II) complex 1 containing a tris(2-pyridylmethyl)amine (tpa) ligand as an inhibitor of β-amyloid fibrillogenesis. [Ru(tpa)(bt)]ClO(4) 1 (bt =2-acetylbenzo[b]thiophene-3-olate) showed significant inhibition of Aβ(1-40) peptide aggregation in vitro, which was confirmed by a Thioflavin T assay and transmission electron microscopy imaging. Topics: Amyloid beta-Peptides; Microscopy, Electron, Transmission; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Pyridines; Ruthenium; Spectrum Analysis	2015

Article

Year

A Novel Tetradentate Ruthenium(II) Complex Containing Tris(2- Pyridylmethyl)amine (tpa) As An Inhibitor Of Beta-amyloid Fibrillation.

Current Alzheimer research, 2015, Volume: 12, Issue:5

We report herein the synthesis and application of a novel tetradentate ruthenium(II) complex 1 containing a tris(2-pyridylmethyl)amine (tpa) ligand as an inhibitor of β-amyloid fibrillogenesis. [Ru(tpa)(bt)]ClO(4) 1 (bt =2-acetylbenzo[b]thiophene-3-olate) showed significant inhibition of Aβ(1-40) peptide aggregation in vitro, which was confirmed by a Thioflavin T assay and transmission electron microscopy imaging.

Topics: Amyloid beta-Peptides; Microscopy, Electron, Transmission; Molecular Structure; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Pyridines; Ruthenium; Spectrum Analysis

2015