amyloid-beta-peptides and arginyl-glycyl-aspartic-acid

amyloid-beta-peptides has been researched along with arginyl-glycyl-aspartic-acid* in 1 studies

Other Studies

1 other study(ies) available for amyloid-beta-peptides and arginyl-glycyl-aspartic-acid

Article	Year
beta-Amyloid protein induces platelet aggregation and supports platelet adhesion. Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3 The amyloid precursor protein (APP) is found in many cells including neurons, endothelial cells and blood platelets. Beta-amyloid protein (beta AP) is derived from APP and is deposited in brain and in cerebral microvasculature of individuals with Alzheimer's disease. In this study we demonstrate that beta AP interacts with human blood platelets. We found that human beta AP peptide (1-40) fibrils aggregate platelets and support their adhesion, and these interactions are mediated through platelet membrane integrin receptors. Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Binding Sites; Fibrinogen; Humans; In Vitro Techniques; Macromolecular Substances; Membrane Glycoproteins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thrombosis; Thrombospondins	1994

Article

Year

beta-Amyloid protein induces platelet aggregation and supports platelet adhesion.

Biochemical and biophysical research communications, 1994, Dec-30, Volume: 205, Issue:3

The amyloid precursor protein (APP) is found in many cells including neurons, endothelial cells and blood platelets. Beta-amyloid protein (beta AP) is derived from APP and is deposited in brain and in cerebral microvasculature of individuals with Alzheimer's disease. In this study we demonstrate that beta AP interacts with human blood platelets. We found that human beta AP peptide (1-40) fibrils aggregate platelets and support their adhesion, and these interactions are mediated through platelet membrane integrin receptors.

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Binding Sites; Fibrinogen; Humans; In Vitro Techniques; Macromolecular Substances; Membrane Glycoproteins; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Platelet Adhesiveness; Platelet Aggregation; Platelet Membrane Glycoproteins; Protein Binding; Thrombosis; Thrombospondins

1994