amycolamicin and kibdelomycin

amycolamicin has been researched along with kibdelomycin* in 1 studies

Other Studies

1 other study(ies) available for amycolamicin and kibdelomycin

ArticleYear
Total Synthesis of the Potent and Broad-Spectrum Antibiotics Amycolamicin and Kibdelomycin.
    Journal of the American Chemical Society, 2021, 12-22, Volume: 143, Issue:50

    The complex and intriguing structures of the antibiotics amycolamicin and kibdelomycin are herein confirmed through total synthesis. Careful titration of the synthetic products reveals that kibdelomycin is the salt form of amycolamicin. This synthesis employs a highly convergent strategy, which provides a modular approach for further SAR studies of this class of antibiotics.

    Topics: Anti-Bacterial Agents; Biological Products; Crystallography, X-Ray; Drug Resistance, Bacterial; Glucosides; Gram-Positive Bacteria; Molecular Conformation; Pyrroles; Pyrrolidinones

2021