Compounds > amsacrine

amsacrine and suramin

amsacrine has been researched along with suramin in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bojanowski, K; Couprie, J; Jacquemin-Sablon, A; Larsen, AK; Lelievre, S; Markovits, J1
Benchokroun, Y; Larsen, AK; Lelièvre, S1
Dilworth, A; Myers, CE; Sinha, BK; Yamazaki, H1
Bernardi, R; Donzelli, M; Negri, C; Scovassi, AI1
Emanuele, S; Giuliano, M; Lauricella, M; Tesoriere, G; Vento, R1

Other Studies

7 other study(ies) available for amsacrine and suramin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Suramin is an inhibitor of DNA topoisomerase II in vitro and in Chinese hamster fibrosarcoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-01, Volume: 89, Issue:7

    Topics: Amsacrine; Animals; Cell Compartmentation; Cell Division; Cricetinae; Cricetulus; DNA Damage; Fibrosarcoma; In Vitro Techniques; Nucleic Acid Denaturation; Saccharomyces cerevisiae; Suramin; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1992
Altered topoisomerase I and II activities in suramin-resistant lung fibrosarcoma cells.
    Molecular pharmacology, 1995, Volume: 47, Issue:5

    Topics: Amsacrine; Animals; Camptothecin; Cell Nucleus; Cricetinae; Cricetulus; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Doxorubicin; Drug Resistance; Etoposide; Fibrosarcoma; Lung Neoplasms; Neoplasm Proteins; Suramin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1995
Suramin inhibits DNA damage in human prostate cancer cells treated with topoisomerase inhibitors in vitro.
    The Prostate, 1993, Volume: 23, Issue:1

    Topics: Amsacrine; Camptothecin; Cell Survival; Chemical Precipitation; DNA Damage; Dose-Response Relationship, Drug; Drug Interactions; Etoposide; Humans; Male; Prostatic Neoplasms; Suramin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1993
Induction of apoptotic cell death by DNA topoisomerase II inhibitors.
    Biochimie, 1995, Volume: 77, Issue:11

    Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carmustine; Cell Survival; Cyclophosphamide; DNA Damage; DNA Topoisomerases, Type II; Etoposide; HeLa Cells; Humans; Intercalating Agents; Suramin; Topoisomerase II Inhibitors

1995
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1998, Volume: 19, Issue:5

    Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Butyrates; Butyric Acid; Camptothecin; Carboplatin; Cisplatin; DNA Damage; Drug Screening Assays, Antitumor; Etoposide; Humans; Paclitaxel; Retinoblastoma; Suramin; Tumor Cells, Cultured

1998