amsacrine has been researched along with podophyllotoxin in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (85.19) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gupta, R | 1 |
| Beck, WT; Danks, MK; Fernandes, DJ | 1 |
| Ehrsson, H; Eksborg, S | 1 |
| Blazka, ME; Henner, WD | 1 |
| Beerman, TA; Sigmund, RD; Woynarowski, JM | 2 |
| Denyer, SP; Dewick, PM; Figgitt, DP; Jackson, DE; Williams, P | 1 |
| Beerman, TA; Cullinan, EB | 1 |
| Beck, WT; Danks, MK; Deneka, DA; Schmidt, CA | 1 |
| Boyce, RA; Hertzberg, RP; Mattern, MR; Schein, PS; Tan, KB | 1 |
| Charcosset, JY; Jacquemin-Sablon, A; Saucier, JM | 1 |
| Ishida, R; Nishimoto, T; Nishizawa, M; Takahashi, T | 1 |
| Jacobson-Kram, D; Lim, M; Liu, LF; Williams, JR | 1 |
| Zwelling, LA | 1 |
| Charcosset, JY; Jacquemin-Sablon, A; Kerrigan, D; Kohn, KW; Mattern, MR; Pommier, Y; Schwartz, RE; Zwelling, LA | 1 |
| Glisson, B; Gupta, R; Ross, W; Smallwood-Kentro, S | 1 |
| Glisson, B; Gupta, R; Hodges, P; Ross, W | 1 |
| Glisson, BS; Hodges, PK; Ross, WE; Smallwood-Kentro, S; Sullivan, DM | 1 |
| Andersson, BS; Beran, M; Estey, EH; Silberman, L; Zwelling, LA | 1 |
| Bezwoda, WR; Derman, DP; Kew, M; Weaving, A | 1 |
| Brattain, MG; Long, BH; Musial, ST | 1 |
| Apostol, JV; Kucuk, O | 1 |
| Crom, WR; Evans, WE; Hutson, PR; Sinkule, JA; Stewart, CF; Yee, GC | 1 |
| Eagan, RT | 1 |
| Klastersky, J; Sculier, JP | 1 |
| Kreuzer, KN; O'Reilly, EK | 1 |
3 review(s) available for amsacrine and podophyllotoxin
| Article | Year |
|---|---|
Drug level monitoring: cytostatics.
Topics: Alkylating Agents; Aminoacridines; Amsacrine; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Busulfan; Chlorambucil; Chromatography, Gas; Chromatography, Liquid; Cisplatin; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Mass Spectrometry; Melphalan; Methotrexate; Mitomycins; Monitoring, Physiologic; Nitrosourea Compounds; Podophyllotoxin; Purines; Thiotepa; Vinca Alkaloids | 1985 |
DNA topoisomerase II as a target of antineoplastic drug therapy.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Chemical Phenomena; Chemistry; Chromatin; Cross-Linking Reagents; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Intercalating Agents; Leukemia, Experimental; Mammals; Mice; Phenotype; Podophyllotoxin; Topoisomerase II Inhibitors | 1985 |
Pharmacokinetics of anticancer drugs in children.
Topics: Aminoacridines; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cyclophosphamide; Etoposide; Humans; Kinetics; Mercaptopurine; Methotrexate; Naphthacenes; Podophyllotoxin; Teniposide; Vinca Alkaloids | 1983 |
1 trial(s) available for amsacrine and podophyllotoxin
| Article | Year |
|---|---|
Combination chemotherapy of hepatocellular cancer. Comparison of adriamycin + VM 26 + 5-fluorouracil with mAMSA + VM 26 + 5-fluorouracil.
Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Podophyllotoxin; Random Allocation; Teniposide; Time Factors | 1987 |
23 other study(ies) available for amsacrine and podophyllotoxin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Tests for the genotoxicity of m-AMSA, etoposide, teniposide and ellipticine in Neurospora crassa.
Topics: Alkaloids; Amsacrine; Ellipticines; Etoposide; Molecular Structure; Mutagenicity Tests; Mutagens; Neurospora crassa; Podophyllotoxin; Teniposide | 1990 |
Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Nucleus; Crithidia; DNA; DNA Topoisomerases, Type II; Drug Resistance; Humans; Leukemia; Podophyllotoxin; Teniposide; Tumor Cells, Cultured | 1990 |
Hypersensitivity of cultured ataxia-telangiectasia cells to etoposide.
Topics: Aminoacridines; Amsacrine; Ataxia Telangiectasia; Bleomycin; Cell Survival; Cells, Cultured; DNA; Etoposide; Fibroblasts; Humans; Podophyllotoxin | 1986 |
DNA minor groove binding agents interfere with topoisomerase II mediated lesions induced by epipodophyllotoxin derivative VM-26 and acridine derivative m-AMSA in nuclei from L1210 cells.
Topics: Amsacrine; Animals; Bisbenzimidazole; Cell Nucleus; Deoxyribonucleoproteins; Distamycins; DNA Damage; DNA, Neoplasm; Indoles; Kinetics; Leukemia L1210; Mice; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1989 |
Topoisomerase II: a potential target for novel antifungal agents.
Topics: Amiloride; Amsacrine; Antifungal Agents; DNA, Superhelical; Etoposide; Molecular Structure; Novobiocin; Plasmids; Podophyllotoxin; Saccharomyces cerevisiae; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1989 |
A study of drug-induced topoisomerase II-mediated DNA lesions on episomal chromatin.
Topics: Amsacrine; Blotting, Southern; Cell Line; Chromatin; Dexamethasone; DNA Damage; DNA Topoisomerases, Type II; Genes; Kinetics; Plasmids; Podophyllotoxin; Teniposide | 1989 |
Increased ATP requirement for activity of and complex formation by DNA topoisomerase II from human leukemic CCRF-CEM cells selected for resistance to teniposide.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Amsacrine; Cell Line; Cell Nucleus; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Resistance; Humans; Kinetics; Podophyllotoxin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Binding; Teniposide; Tumor Cells, Cultured | 1989 |
Elevated topoisomerase II activity and altered chromatin in nitrogen mustard-resistant human cells.
Topics: Amsacrine; Burkitt Lymphoma; Cell Line; Cell Survival; Chromatin; DNA Topoisomerases, Type II; Drug Resistance; Humans; Kinetics; Mechlorethamine; Novobiocin; Podophyllotoxin; Teniposide; Tumor Stem Cell Assay | 1987 |
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1988 |
Reduced DNA topoisomerase II activity and drug-stimulated DNA cleavage in 9-hydroxyellipticine resistant cells.
Topics: Alkaloids; Amsacrine; Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; Cricetulus; DNA; Drug Resistance; Ellipticines; Podophyllotoxin; Topoisomerase II Inhibitors | 1988 |
Cross-resistance of novobiocin-resistant BHK cell line to topoisomerase II inhibitors.
Topics: Amsacrine; Animals; Cell Line; Colchicine; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Novobiocin; Podophyllotoxin; Vinblastine | 1988 |
Induction of sister chromatid exchanges by inhibitors of topoisomerases.
Topics: Amsacrine; Animals; Camptothecin; Cells, Cultured; Cricetinae; DNA Topoisomerases, Type I; Enzyme Inhibitors; Fibroblasts; Podophyllotoxin; Sister Chromatid Exchange; Teniposide | 1986 |
Reduced formation of protein-associated DNA strand breaks in Chinese hamster cells resistant to topoisomerase II inhibitors.
Topics: Alkaloids; Aminoacridines; Amsacrine; Animals; Biological Transport; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Repair; Drug Resistance; Ellipticines; Lung; Podophyllotoxin; Proteins; Topoisomerase II Inhibitors | 1986 |
Characterization of acquired epipodophyllotoxin resistance in a Chinese hamster ovary cell line: loss of drug-stimulated DNA cleavage activity.
Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cricetinae; Cricetulus; DNA; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Female; Ovary; Podophyllotoxin | 1986 |
Cross-resistance to intercalating agents in an epipodophyllotoxin-resistant Chinese hamster ovary cell line: evidence for a common intracellular target.
Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Line; Cricetinae; Cricetulus; DNA; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Intercalating Agents; Mitoxantrone; Ovary; Podophyllotoxin | 1986 |
Proliferation dependence of topoisomerase II mediated drug action.
Topics: Aminoacridines; Amsacrine; Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; DNA Topoisomerases, Type II; Etoposide; Female; HeLa Cells; Humans; Intercalating Agents; Kinetics; Leukemia L1210; Mice; Ovary; Plasmids; Podophyllotoxin | 1986 |
The interaction between nuclear topoisomerase II activity from human leukemia cells, exogenous DNA, and 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) or 4-(4,6-O-ethylidene-beta-D-glucopyranoside) (VP-16) indicates the sensitivity of the cells t
Topics: Amsacrine; Animals; Cell Line; Cell Nucleus; Crithidia; DNA; DNA Topoisomerases, Type II; Humans; Kinetics; Leukemia, Myeloid, Acute; Podophyllotoxin | 1987 |
Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.
Topics: Adenocarcinoma; Aminoacridines; Amsacrine; Cells, Cultured; DNA; DNA Repair; Etoposide; Humans; Lung Neoplasms; Podophyllotoxin; Teniposide | 1985 |
Amsacrine and etoposide induced paralytic ileus in a patient with acute myelomonocytic leukemia.
Topics: Aged; Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Etoposide; Humans; Leukemia, Myeloid, Acute; Male; Podophyllotoxin | 1985 |
Pilot studies of various combinations of dibromodulcitol, VP-16, and AMSA.
Topics: Aged; Aminoacridines; Amsacrine; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Middle Aged; Mitolactol; Neoplasms; Pilot Projects; Podophyllotoxin | 1982 |
[Prospects of new chemotherapies].
Topics: Aminoacridines; Amsacrine; Antineoplastic Agents; Cisplatin; Drug Evaluation; Drug Therapy, Combination; Etoposide; Female; Humans; Male; Neoplasms; Podophyllotoxin; Vinblastine; Vindesine | 1982 |
A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Antineoplastic Agents; Bacteriophage T4; Binding Sites; DNA Damage; DNA Topoisomerases, Type II; DNA, Superhelical; Ellipticines; Enzyme Inhibitors; Filtration; Glycine; Mitoxantrone; Molecular Sequence Data; Oxolinic Acid; Podophyllotoxin; Point Mutation; Topoisomerase II Inhibitors; Valine | 2002 |