amsacrine has been researched along with novobiocin in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (41.18) | 18.7374 |
| 1990's | 16 (47.06) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, IH; Jun, KY; Kwon, Y; Lee, E; Lee, ES; Na, Y; Park, SE | 1 |
| Kulkarni, P; Meda, N; Medapi, B; Sriram, D; Yogeeswari, P | 1 |
| Bist, G; Jun, KY; Kadayat, TM; Kwon, Y; Lee, ES; Park, S; Shrestha, A; Thapa Magar, TB | 1 |
| Constantinou, A; Grdina, D; Huberman, E; Kiguchi, K | 1 |
| DeMarini, DM; Lawrence, BK | 2 |
| Lorico, A; Rappa, G; Sartorelli, AC | 1 |
| Adachi, K; Andrea, JE; Morgan, AR | 1 |
| Aller, P; Bernabeu, C; Cabañas, C; Mata, F; Rius, C; Zorrilla, AR | 1 |
| Buddenbaum, WE; Don, AL; Elkind, MM; Kosaka, T; Shibuya, ML; Suciu, D; Utsumi, H | 1 |
| Lyons, BW; Warters, RL | 1 |
| Buddenbaum, WE; Elkind, MM; Kosaka, T; Shibuya, ML; Utsumi, H | 1 |
| Elkind, MM; Shibuya, ML; Utsumi, H | 1 |
| Alnemri, ES; Litwack, G | 1 |
| Kort, L; Rowley, R | 1 |
| Constantinou, A; Henning-Chubb, C; Huberman, E | 1 |
| Kennedy, K; Li, TM; Lyons, BW; Warters, RL | 1 |
| Denyer, SP; Dewick, PM; Figgitt, DP; Jackson, DE; Williams, P | 1 |
| Boyce, RA; Hertzberg, RP; Mattern, MR; Schein, PS; Tan, KB | 1 |
| Beerman, TA; Sigmund, RD; Woynarowski, JM | 1 |
| Ishida, R; Nishimoto, T; Nishizawa, M; Takahashi, T | 1 |
| Besterman, J; Chang, KJ; Cuatrecasas, P; Hsieh, T; LeVine, H; Sahyoun, N; Sander, M; Wolf, M | 1 |
| Doida, Y; Fero, ML; Guo, XC; Morgan, WF; Shadley, JD | 1 |
| Mui, SC; Strauss, PR; Todt, JC; Zhang, LH | 1 |
| Denstman, SC; Dillehay, LE; Williams, JR | 1 |
| Darkin, S; Marshall, B; Ralph, RK | 1 |
| Kohn, KW; Mattern, MR; Pommier, Y; Schwartz, RE; Zwelling, LA | 1 |
| Sitailo, LA; Zagariya, AM | 1 |
| Corbett, AH; Osheroff, N; Robinson, MJ | 1 |
| Corbett, AH; Hong, D; Osheroff, N | 1 |
| Jo, K; Topal, MD | 1 |
| Falaschi, A; Ochem, A; Phan, TN; Tuteja, N; Tuteja, R | 1 |
| Phan, TN; Tuteja, N | 1 |
34 other study(ies) available for amsacrine and novobiocin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
3-(3-Butylamino-2-hydroxy-propoxy)-1-hydroxy-xanthen-9-one acts as a topoisomerase IIα catalytic inhibitor with low DNA damage.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Biocatalysis; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Structure-Activity Relationship; Topoisomerase II Inhibitors; Xanthones | 2013 |
Development of acridine derivatives as selective Mycobacterium tuberculosis DNA gyrase inhibitors.
Topics: Acridines; Animals; Antitubercular Agents; Bacterial Proteins; Cell Line; Cell Survival; Chlorobenzoates; DNA Gyrase; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Ether-A-Go-Go Potassium Channels; Gene Expression; Heart Rate; Macrophages; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Piperidines; Quinolines; Structure-Activity Relationship; Topoisomerase II Inhibitors; Zebrafish; Zebrafish Proteins | 2016 |
Novel 2-aryl-4-(4'-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors.
Topics: Antigens, Neoplasm; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA; DNA Topoisomerases, Type II; DNA-Binding Proteins; Humans; Molecular Docking Simulation; Pyridines; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2017 |
The effect of topoisomerase inhibitors on the expression of differentiation markers and cell cycle progression in human K-562 leukemia cells.
Topics: Amsacrine; Aphidicolin; Cell Cycle; Cell Differentiation; Cycloheximide; Deoxyadenosines; Dose-Response Relationship, Drug; Etoposide; G2 Phase; Hemoglobins; Humans; Kinetics; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Melanins; Mitosis; Novobiocin; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Prophage induction by DNA topoisomerase II poisons and reactive-oxygen species: role of DNA breaks.
Topics: Amsacrine; Azides; Bacteriophage lambda; Dactinomycin; DNA Damage; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Escherichia coli; Free Radicals; Hydrogen Peroxide; Lysogeny; Nalidixic Acid; Novobiocin; Oxolinic Acid; Oxygen; Paraquat; Sodium Azide; SOS Response, Genetics; Teniposide; Topoisomerase II Inhibitors; Virus Replication | 1992 |
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Fluorometric assays for DNA topoisomerases and topoisomerase-targeted drugs: quantitation of catalytic activity and DNA cleavage.
Topics: Amsacrine; Animals; Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Circular; DNA, Single-Stranded; DNA, Superhelical; Ethidium; Fluorescence; Fluorometry; Hydrogen-Ion Concentration; Kinetics; Novobiocin; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1991 |
Differentiation of human promonocytic leukemia U-937 cells with DNA topoisomerase II inhibitors: induction of vimentin gene expression.
Topics: Amsacrine; Antigens, Differentiation; Cell Differentiation; Cell Division; Etoposide; Gene Expression Regulation, Leukemic; Humans; Leukemia, Monocytic, Acute; Novobiocin; Oxygen; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Vimentin | 1991 |
Amsacrine-induced lesions in DNA and their modulation by novobiocin and 2,4-dinitrophenol.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Amsacrine; Animals; Cell Line; Cell Survival; Cricetinae; Cricetulus; Dinitrophenols; DNA; DNA Damage; DNA, Single-Stranded; Kinetics; Novobiocin | 1991 |
Inhibition of replicon cluster ligation into chromosomal DNA at elevated temperatures.
Topics: Amsacrine; Caffeine; Chromatin; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Replication; DNA, Single-Stranded; HeLa Cells; Histones; Hot Temperature; Humans; Hydrogen-Ion Concentration; Micrococcal Nuclease; Novobiocin; Replicon; Topoisomerase II Inhibitors | 1990 |
Abrogation by novobiocin of cytotoxicity due to the topoisomerase II inhibitor amsacrine in Chinese hamster cells.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Amsacrine; Animals; Cell Survival; Cells, Cultured; Cricetinae; Dinitrophenols; DNA; DNA Repair; Novobiocin; Proteins; Topoisomerase II Inhibitors | 1990 |
Novobiocin inhibits the repair of potentially lethal damage but not the repair of sublethal damage.
Topics: Amsacrine; Animals; Cell Line; Cricetinae; DNA Damage; DNA Repair; Etoposide; Novobiocin; Teniposide; Topoisomerase II Inhibitors | 1990 |
Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s).
Topics: Amsacrine; Calcium; Cell Division; Cell Line; Cell Survival; Chromatin; DNA; DNA, Neoplasm; Humans; Lymphocytes; Models, Biological; Novobiocin; Nucleosomes; Topoisomerase II Inhibitors; Triamcinolone Acetonide | 1990 |
Novobiocin, nalidixic acid, etoposide, and 4'-(9-acridinylamino)methanesulfon-m-anisidide effects on G2 and mitotic Chinese hamster ovary cell progression.
Topics: Amsacrine; Animals; Cell Line; Cell Survival; DNA Damage; Etoposide; Interphase; Metaphase; Mitosis; Nalidixic Acid; Novobiocin; RNA; Topoisomerase II Inhibitors | 1989 |
Novobiocin- and phorbol-12-myristate-13-acetate-induced differentiation of human leukemia cells associated with a reduction in topoisomerase II activity.
Topics: Amsacrine; Cell Differentiation; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Humans; Leukemia, Promyelocytic, Acute; Novobiocin; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate | 1989 |
Topoisomerase activity in irradiated mammalian cells.
Topics: Amsacrine; Caffeine; Cell Survival; DNA Damage; DNA Repair; DNA Topoisomerases, Type I; DNA, Mitochondrial; Dose-Response Relationship, Radiation; HeLa Cells; Humans; Intercalating Agents; Novobiocin; X-Rays | 1989 |
Topoisomerase II: a potential target for novel antifungal agents.
Topics: Amiloride; Amsacrine; Antifungal Agents; DNA, Superhelical; Etoposide; Molecular Structure; Novobiocin; Plasmids; Podophyllotoxin; Saccharomyces cerevisiae; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1989 |
Elevated topoisomerase II activity and altered chromatin in nitrogen mustard-resistant human cells.
Topics: Amsacrine; Burkitt Lymphoma; Cell Line; Cell Survival; Chromatin; DNA Topoisomerases, Type II; Drug Resistance; Humans; Kinetics; Mechlorethamine; Novobiocin; Podophyllotoxin; Teniposide; Tumor Stem Cell Assay | 1987 |
Topoisomerase-II-mediated lesions in nascent DNA: comparison of the effects of epipodophyllotoxin derivatives, VM-26 and VP-16, and 9-anilinoacridine derivatives, m-AMSA and o-AMSA.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Cross-Linking Reagents; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Etoposide; Leukemia L1210; Mice; Novobiocin; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors | 1988 |
Cross-resistance of novobiocin-resistant BHK cell line to topoisomerase II inhibitors.
Topics: Amsacrine; Animals; Cell Line; Colchicine; Cytarabine; DNA Damage; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Novobiocin; Podophyllotoxin; Vinblastine | 1988 |
Mutagenicity of topoisomerase-active agents in bacteriophage T4.
Topics: Amsacrine; Dactinomycin; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Ellipticines; Mutation; Nalidixic Acid; Novobiocin; Oxolinic Acid; T-Phages | 1988 |
Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells.
Topics: Aminoacridines; Amsacrine; Animals; Cell Differentiation; Cell Line; DNA Topoisomerases, Type II; Drosophila melanogaster; Enzyme Activation; Kinetics; Leukemia, Myeloid, Acute; Male; Novobiocin; Phorbol Esters; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Topoisomerase II Inhibitors | 1986 |
Potentiation of sister chromatid exchange by 3-aminobenzamide is not modulated by topoisomerases or proteases.
Topics: Aminoacridines; Amsacrine; Animals; Antipain; Benzamides; Cricetinae; Cricetulus; DNA Topoisomerases, Type I; Female; Methyl Methanesulfonate; Nalidixic Acid; Novobiocin; Peptide Hydrolases; Poly(ADP-ribose) Polymerases; Sister Chromatid Exchange | 1986 |
Role for topoisomerases in the release of DNA into the detergent-soluble fraction of eukaryotic cells.
Topics: Aminoacridines; Amsacrine; Animals; Camptothecin; Detergents; DNA; DNA Topoisomerases, Type I; Intercalating Agents; Kinetics; Mice; Novobiocin; Solubility; Spleen; Teniposide; Thymidine | 1986 |
Cell cycle dependence of sister chromatid exchange induction by DNA topoisomerase II inhibitors in Chinese hamster V79 cells.
Topics: Amsacrine; Cell Cycle; Cell Line; DNA; Flow Cytometry; Novobiocin; Sister Chromatid Exchange; Topoisomerase II Inhibitors | 1987 |
Evidence that mAMSA induces topoisomerase action.
Topics: Aminoacridines; Aminocoumarins; Amsacrine; Animals; Cell Line; Cell Nucleus; Coumarins; DNA Topoisomerases, Type I; DNA, Neoplasm; Intercalating Agents; Kinetics; Mast-Cell Sarcoma; Mice; Novobiocin; Sarcoma, Experimental | 1983 |
Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide.
Topics: Aminoacridines; Amsacrine; Animals; Benzamides; Cell Nucleus; Deoxyribonucleoproteins; DNA, Neoplasm; Ethidium; Intercalating Agents; Kinetics; Leukemia L1210; Mice; Novobiocin | 1984 |
The influence of antibiotics and antitumor agents on the relaxation activity of Pisum sativum leaf chloroplast topoisomerase I.
Topics: Amiloride; Amsacrine; Anti-Bacterial Agents; Antineoplastic Agents; Camptothecin; Chloroplasts; DNA Topoisomerases, Type I; DNA, Plant; Ethidium; Heparin; Indoles; Magnesium; Nalidixic Acid; Novobiocin; Pisum sativum; Polyamines; Topoisomerase I Inhibitors | 1995 |
Effects of topoisomerase II-targeted drugs on enzyme-mediated DNA cleavage and ATP hydrolysis: evidence for distinct drug interaction domains on topoisomerase II.
Topics: Adenosine Triphosphate; Amsacrine; Animals; Anti-Infective Agents; Antineoplastic Agents; Binding Sites; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Bacterial; Drosophila melanogaster; Escherichia coli; Etoposide; Fluoroquinolones; Genistein; Hydrolysis; Isoflavones; Novobiocin; Plasmids; Quercetin; Quinolones; Topoisomerase II Inhibitors | 1993 |
Exploiting mechanistic differences between drug classes to define functional drug interaction domains on topoisomerase II. Evidence that several diverse DNA cleavage-enhancing agents share a common site of action on the enzyme.
Topics: Amsacrine; Animals; Anti-Infective Agents; Binding Sites; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type II; DNA, Superhelical; Drosophila melanogaster; Drug Interactions; Etoposide; Fluoroquinolones; Genistein; Growth Inhibitors; Isoflavones; Kinetics; Novobiocin; Protein Binding; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1993 |
Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs.
Topics: Amsacrine; Antineoplastic Agents; Binding Sites; Daunorubicin; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA Nucleotidyltransferases; DNA Topoisomerases, Type I; Ellipticines; Enzyme Inhibitors; Integrases; Intercalating Agents; Kinetics; Lysine; Nalidixic Acid; Novobiocin; Oxolinic Acid; Point Mutation; Recombinant Proteins; Recombinases; Topoisomerase I Inhibitors | 1996 |
Inhibition of DNA unwinding and ATPase activities of human DNA helicase II by chemotherapeutic agents.
Topics: Adenosine Triphosphatases; Amsacrine; Antineoplastic Agents; Aphidicolin; Camptothecin; Dactinomycin; Daunorubicin; DNA; DNA Helicases; Ellipticines; Enzyme Inhibitors; Ethidium; Etoposide; Genistein; Humans; Isoflavones; Nogalamycin; Novobiocin; Topoisomerase I Inhibitors | 1997 |
Inhibition of pea chloroplast DNA helicase unwinding and ATPase activities by DNA-interacting ligands.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amsacrine; Camptothecin; Chloroplasts; Dactinomycin; Daunorubicin; DNA Helicases; Ellipticines; Ethidium; Etoposide; Genistein; Hydrolysis; Intercalating Agents; Ligands; Nogalamycin; Novobiocin; Pisum sativum | 1998 |