amsacrine has been researched along with merbarone in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartus, JO; Drake, FH; Hertzberg, RP; Hofmann, GA; Johnson, RK; Mattern, MR; Mirabelli, CK; Mong, SM | 1 |
| Berney, JJ; Chresta, CM; Delgado, C; Francis, GE; Patel, P; Tejedor, MC | 1 |
| Falck, J; Jensen, LH; Jensen, PB; Nitiss, JL; Roerth, M; Rose, A; Sehested, M; Wessel, I | 1 |
3 other study(ies) available for amsacrine and merbarone
| Article | Year |
|---|---|
In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone.
Topics: Amsacrine; Animals; Antineoplastic Agents; Camptothecin; DNA; DNA Damage; Leukemia, Experimental; Mice; Teniposide; Thiobarbiturates; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1989 |
Effects of DNA topoisomerase II inhibitors on human bone marrow progenitor cells.
Topics: Adult; Alkenes; Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Drug Screening Assays, Antitumor; Etoposide; Hematopoietic Stem Cells; Humans; Polyenes; Pyrones; Thiobarbiturates; Topoisomerase II Inhibitors | 1994 |
Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Small Cell; Catalysis; CHO Cells; Consensus Sequence; Cricetinae; Cricetulus; DNA Damage; DNA Mutational Analysis; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Lung Neoplasms; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Isoforms; Razoxane; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiobarbiturates; Topoisomerase II Inhibitors; Tumor Stem Cell Assay | 1999 |