Compounds > amsacrine

amsacrine and lysine

amsacrine has been researched along with lysine in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McMahon, J; Nitiss, JL; Vilalta, PM; Wu, H1
Jo, K; Topal, MD1
Austin, CA; Lakey, JH; Leontiou, C1

Other Studies

3 other study(ies) available for amsacrine and lysine

ArticleYear
Mutations in the gyrB domain of eukaryotic topoisomerase II can lead to partially dominant resistance to etoposide and amsacrine.
    Molecular pharmacology, 1994, Volume: 46, Issue:4

    Topics: Amino Acid Sequence; Amsacrine; Base Sequence; DNA Gyrase; DNA Topoisomerases, Type II; Drug Resistance; Etoposide; Glycine; Lysine; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Saccharomyces cerevisiae

1994
Changing a leucine to a lysine residue makes NaeI endonuclease hypersensitive to DNA intercalative drugs.
    Biochemistry, 1996, Aug-06, Volume: 35, Issue:31

    Topics: Amsacrine; Antineoplastic Agents; Binding Sites; Daunorubicin; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA Nucleotidyltransferases; DNA Topoisomerases, Type I; Ellipticines; Enzyme Inhibitors; Integrases; Intercalating Agents; Kinetics; Lysine; Nalidixic Acid; Novobiocin; Oxolinic Acid; Point Mutation; Recombinant Proteins; Recombinases; Topoisomerase I Inhibitors

1996
Mutation E522K in human DNA topoisomerase IIbeta confers resistance to methyl N-(4'-(9-acridinylamino)-phenyl)carbamate hydrochloride and methyl N-(4'-(9-acridinylamino)-3-methoxy-phenyl) methane sulfonamide but hypersensitivity to etoposide.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Amino Acid Sequence; Amsacrine; Antineoplastic Agents; DNA; DNA Topoisomerases, Type II; Enzyme Stability; Etoposide; Glutamic Acid; Humans; Lysine; Models, Molecular; Mutation; Topoisomerase II Inhibitors; Tranexamic Acid

2004